| C06807 |
Acetophenazine |
(P) unclassified |
| C07521 |
Thiopental |
(P) unclassified |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00236 |
Atovaquone (JAN/USP/INN); Mepron (TN) |
(P) unclassified |
| D00241 |
Baclofen (JP18/USP/INN); Kemstro (TN); Lioresal (TN) |
(P) unclassified |
| D00270 |
Chlorpromazine (USP/INN); Thorazine (TN) |
(P) unclassified |
| D00276 |
Clarithromycin (JP18/USP/INN); Biaxin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00283 |
Clozapine (JAN/USP/INN); Clozaril (TN) |
(P) Enzyme: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00295 |
Cimetidine (JP18/USP/INN); Tagamet (TN) |
(P) CYP inhibition: CYP3A4 |
| D00320 |
Fentanyl (JAN/USP/INN); Duragesic (TN); Subsys (TN) |
(P) Enzyme: CYP3A4 |
| D00346 |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
(P) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00373 |
Thioridazine (USP/INN); Mellaril-S (TN) |
(P) unclassified |
| D00390 |
Triflupromazine (USP/INN); Vesprin (TN) |
(P) unclassified |
| D00403 |
Methotrimeprazine (USP); Levomepromazine (USAN/INN); Levoprome (TN) |
(P) unclassified |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00427 |
Ritonavir (JAN/USP/INN); Norvir (TN) |
(CI) CYP induction: CYP2C9 |
| D00430 |
Secobarbital (USP/INN); Seconal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 |
| D00454 |
Olanzapine (JAN/USP/INN); Zyprexa (TN) |
(P) unclassified |
| D00474 |
Primidone (JP18/USP/INN); Mysoline (TN) |
(P) unclassified |
| D00479 |
Prochlorperazine maleate (JP18/USP); Compazine (TN) |
(P) unclassified |
| D00493 |
Prochlorperazine (JAN/USP/INN); Compro (TN) |
(P) unclassified |
| D00498 |
Pentazocine (JP18/USP/INN); Fortral (TN) |
(P) unclassified |
| D00499 |
Pentobarbital (USP/INN); Nembutal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00500 |
Pentobarbital sodium (JAN/USP); Nembutal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00503 |
Perphenazine (JP18/USP/INN); Trilafon (TN) |
(P) unclassified |
| D00505 |
Phenelzine sulfate (USP); Nardil (TN) |
(P) unclassified |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ / CYP induction: CYP2C9 |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) Enzyme: CYP2C9 |
| D00528 |
Caffeine (USP); Anhydrous caffeine (JP18); Anhydrous caffeine (TN); Respia (TN) |
(P) unclassified |
| D00545 |
Isoflurane (JP18/USP/INN); Forane (TN) |
(P) unclassified |
| D00546 |
Desflurane (JAN/USP/INN); Suprane (TN) |
(P) unclassified |
| D00549 |
Propofol (JAN/USP/INN); Diprivan (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00555 |
Amobarbital (JP18/INN); Isomytal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00563 |
Mirtazapine (JAN/USP/INN); Remeron (TN); Reflex (TN) |
(P) Enzyme: CYP3A4 |
| D00606 |
Guanfacine hydrochloride (JAN/USP); Intuniv (TN); Tenex (TN) |
(P) Enzyme: CYP3A4 |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 |
| D00697 |
Flumazenil (JAN/USP/INN); Romazicon (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00698 |
Aprobarbital (INN); Alurate (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00699 |
Butabarbital sodium (USP); Secbutabarbital sodium (INN); Butabarb (TN); Butisol sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00700 |
Mephobarbital (JAN/USP); Methylphenobarbital (INN); Mebaral (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ / CYP induction: CYP2C9 |
| D00710 |
Valproate sodium (USAN); Sodium valproate (JP18); Depakene (TN); Selenica (TN) |
(P) unclassified |
| D00712 |
Methohexital sodium (USP); Brevital sodium (TN) |
(P) Target: GABRA1 |
| D00713 |
Thiamylal sodium (JP18); Surital (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00714 |
Thiopental sodium (JP18/USP/INN); Pentothal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D00754 |
Thalidomide (JAN/USP/INN); Thalomid (TN); Thaled (TN) |
(P) unclassified |
| D00783 |
Botulinum toxin type A (JAN); Botox (TN); Dysport (TN) |
(P) unclassified |
| D00785 |
Selegiline hydrochloride (JAN/USP); Eldepryl (TN) |
(P) Enzyme: CYP3A4 |
| D00788 |
Acetophenazine maleate (USAN); Tindal (TN) |
(P) unclassified |
| D00789 |
Chlorpromazine hydrochloride (JP18/USP); Sonazine (TN) |
(P) unclassified |
| D00791 |
Fluphenazine hydrochloride (JAN/USP); Prolixin (TN) |
(P) unclassified |
| D00792 |
Fluphenazine enanthate (JP18/USP); Prolixin enanthate (TN) |
(P) unclassified |
| D00793 |
Fluphenazine decanoate (JAN/USP); Prolixin decanoate (TN) |
(P) unclassified |
| D00795 |
Mesoridazine besylate (USP); Serentil (TN) |
(P) unclassified |
| D00797 |
Promazine hydrochloride (USP); Sparine (TN) |
(P) unclassified |
| D00798 |
Thioridazine hydrochloride (JP18/USP); Mellaril (TN) |
(P) unclassified |
| D00799 |
Trifluoperazine hydrochloride (JAN/USP); Stelazine (TN) |
(P) unclassified |
| D00800 |
Triflupromazine hydrochloride (JAN/USP); Vesprin (TN) |
(P) unclassified |
| D00818 |
Maprotiline hydrochloride (JP18/USP); Ludiomil (TN) |
(P) unclassified |
| D00824 |
Fluvoxamine maleate (JP18/USP); Luvox (TN) |
(P) CYP inhibition: CYP3A4 |
| D00826 |
Tranylcypromine sulfate (USP); Parnate (TN) |
(P) unclassified |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00836 |
Buprenorphine hydrochloride (JP18/USP); Buprenex (TN) |
(P) Enzyme: CYP3A4 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D01071 |
Hexobarbital (JAN/INN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01097 |
Lazabemide hydrochloride (JAN/USAN); Tempium (TN) |
(P) unclassified |
| D01130 |
Thiethylperazine maleate (JAN/USP); Norzine (TN) |
(P) unclassified |
| D01145 |
Azelnidipine (JP18/INN); Calblock (TN) |
(P) Enzyme: CYP3A4 |
| D01177 |
Remifentanil hydrochloride (JAN/USAN); Ultiva (TN) |
(P) unclassified |
| D01205 |
Dexmedetomidine hydrochloride (JAN/USP); Igalmi (TN); Precedex (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 / Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01280 |
Warfarin potassium (JP18); Athrombin-K (TN) |
(P) Enzyme: CYP2C9 |
| D01287 |
Levobupivacaine hydrochloride (JAN/USAN); Chirocaine (TN) |
(P) Enzyme: CYP3A4 |
| D01310 |
Secobarbital sodium (JAN/USP); Seconal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01355 |
Tramadol hydrochloride (JP18/USP); Ultram (TN) |
(P) Enzyme: CYP3A4 |
| D01382 |
Metharbital (JAN/INN); Gemonil (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01389 |
Chlophedianol hydrochloride (USAN); Clofedanol hydrochloride (JP18); Coldrin (TN) |
(P) unclassified |
| D01399 |
Fentanyl citrate (JP18/USP); Abstral (TN); Fentora (TN); Lazanda (TN); Oralet (TN) |
(P) Enzyme: CYP3A4 |
| D01412 |
Perazine maleate (JAN) |
(P) unclassified |
| D01447 |
Thioproperazine mesilate (JAN); Thioproperazine mesylate |
(P) unclassified |
| D01448 |
Trifluoperazine maleate (JAN); Trifluoperazine (TN) |
(P) unclassified |
| D01485 |
Propericiazine (JAN); Periciazine; Neuleptil (TN) |
(P) unclassified |
| D01501 |
Isoniazid calcium pyruvinate (JAN); Pyruvic acid calcium isoniazid |
(P) unclassified |
| D01520 |
Levomepromazine hydrochloride (JAN/USAN); Nozinan (TN) |
(P) unclassified |
| D01740 |
Barbital (JP18/INN); Barbital (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D01860 |
Perazine dimalonate (JAN) |
(P) unclassified |
| D01888 |
Safrazine hydrochloride (JAN) |
(P) unclassified |
| D01935 |
Vinorelbine tartrate (USP); Vinorelbine ditartrate (JAN); KW 2307; Navelbine (TN) |
(P) Enzyme: CYP3A4 |
| D02002 |
Isoniazid sodium methanesulfonate hydrate (JAN); Isoniazid sodium methanesulfonate monohydrate; Isoniazid sodium methanesulfonate; IHMS; Neoiscotin (TN) |
(P) unclassified |
| D02022 |
Prochlorperazine mesilate (JAN); Prochlorperazine dimethanesulfonate; Novamin (TN) |
(P) unclassified |
| D02037 |
Perphenazine maleate (JP18); PZC (TN) |
(P) unclassified |
| D02102 |
Methadone hydrochloride (JAN/USP); Dolophine hydrochloride (TN) |
(P) Enzyme: CYP2C9 CYP3A4 / CYP induction: CYP3A4 |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) Enzyme: CYP2C9 |
| D02163 |
Fluphenazine maleate (JAN); Flumezin (TN) |
(P) unclassified |
| D02227 |
Pentazocine hydrochloride (JAN/USP); Sosegon (TN); Talacen (TN) |
(P) unclassified |
| D02245 |
Trimeprazine tartrate (USP); Alimemazine tartrate (JP18); Alimezine (TN) |
(P) unclassified |
| D02248 |
Levomepromazine maleate (JP18/USAN); Hirnamin (TN) |
(P) unclassified |
| D02252 |
Amobarbital sodium (JAN/USP); Amytal sodium (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02253 |
Pentobarbital calcium (JP18); Ravona (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02274 |
Dantrolene sodium (USP); Dantrolene sodium hydrate (JP18); Dantrium (TN); Ryanodex (TN) |
(P) unclassified |
| D02283 |
Iomazenil (123I) (JAN/INN); Benzodine (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02354 |
Thiethylperazine (USAN/INN) |
(P) unclassified |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02559 |
Toloxatone (INN); Humoryl (TN) |
(P) unclassified |
| D02560 |
Brofaromine (INN); Consonar (TN) |
(P) unclassified |
| D02561 |
Moclobemide (USAN/INN); Aurorix (TN) |
(P) unclassified |
| D02562 |
Rasagiline mesylate (USAN); Rasagiline mesilate (JAN); Azilect (TN) |
(P) unclassified |
| D02563 |
Befloxatone (INN) |
(P) unclassified |
| D02564 |
Pargyline hydrochloride (USAN); Eutonyl (TN) |
(P) unclassified |
| D02579 |
Iproniazid (INN) |
(P) unclassified |
| D02580 |
Isocarboxazid (INN); Marplan (TN) |
(P) unclassified |
| D02581 |
Cimoxatone (INN) |
(P) unclassified |
| D02604 |
Acepromazine maleate (USP) |
(P) unclassified |
| D02605 |
Methoxypromazine maleate |
(P) unclassified |
| D02607 |
Mepazine acetate |
(P) unclassified |
| D02608 |
Perazine fendizoate (JAN) |
(P) unclassified |
| D02609 |
Prochlorperazine edisylate (USP); Compazine syrup (TN) |
(P) unclassified |
| D02610 |
Thiethylperazine malate (JAN); Torecan (TN) |
(P) unclassified |
| D02618 |
Butobarbital (BAN); Butethal; Neonal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D02642 |
Butaperazine (USAN) |
(P) unclassified |
| D02643 |
Butaperazine maleate (USAN) |
(P) unclassified |
| D02644 |
Carphenazine maleate (USAN); Proketazine (TN) |
(P) unclassified |
| D02653 |
Cyclophenazine hydrochloride (USAN) |
(P) unclassified |
| D02671 |
Mesoridazine (USAN/INN); Lidanar (TN) |
(P) unclassified |
| D02679 |
Piperacetazine (USAN/INN); Quide (TN) |
(P) unclassified |
| D02680 |
Pipotiazine palmitate (USAN); Piportil depot (TN) |
(P) unclassified |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02735 |
Rimabotulinumtoxin B (USAN); Botulinum toxin type B (JAN); Myobloc (TN) |
(P) unclassified |
| D02817 |
Allobarbital (USAN/INN) |
(P) unclassified |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03180 |
Butabarbital (USP); Secbutabarbital (BAN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D03182 |
Butalbital (USP/INN); Sandoptal (TN) |
(P) unclassified |
| D03239 |
Ladostigil tartrate (USAN) |
(P) unclassified |
| D03248 |
Clorgiline (INN); Clorgyline |
(P) unclassified |
| D03274 |
Chlorpromazine hibenzate (JAN); Contomin (TN) |
(P) unclassified |
| D03409 |
Caroxazone (USAN/INN) |
(P) unclassified |
| D03503 |
Cimetidine hydrochloride (USP); Cimetidine hydrochloride (TN) |
(P) CYP inhibition: CYP3A4 |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP induction: CYP3A4 |
| D03731 |
Selegiline (USAN/INN); Emsam (TN) |
(P) Enzyme: CYP3A4 |
| D03733 |
Mofegiline hydrochloride (USAN) |
(P) unclassified |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04034 |
Chlorpromazine phenolphthalinate (JAN); Wintermin (TN) |
(P) unclassified |
| D04038 |
Perphenazine fendizoate (JAN); PZC (TN) |
(P) unclassified |
| D04077 |
Eterobarb (USAN/INN); Antilon (TN) |
(P) unclassified |
| D04092 |
Etryptamine acetate (USAN) |
(P) unclassified |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04681 |
Lazabemide (USAN/INN) |
(P) unclassified |
| D04965 |
Perphenazine hydrochloride; Perphenazine dihydrochloride; PZC intramuscular injection (TN) |
(P) unclassified |
| D04985 |
Methohexital (USP/INN) |
(P) Target: GABRA1 |
| D05033 |
Milacemide hydrochloride (USAN) |
(P) unclassified |
| D05039 |
Minaprine (USAN/INN); Cantor (TN) |
(P) unclassified |
| D05040 |
Minaprine hydrochloride (USAN) |
(P) unclassified |
| D05177 |
Nitisinone (JAN/USAN/INN); Orfadin (TN) |
(P) CYP inhibition: CYP2C9 |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D05928 |
Stiripentol (JAN/USAN/INN); Diacomit (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 CYP2C9 |
| D06106 |
Thiamylal |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D06405 |
Nalfurafine hydrochloride (JAN/USAN) |
(P) Enzyme: CYP3A4 |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D06887 |
Talbutal (INN); Lotusate (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D07065 |
Acepromazine (INN); Concentrat vo34 (TN) |
(P) unclassified |
| D07132 |
Buprenorphine (JAN/INN); Temgesic (TN) |
(P) Enzyme: CYP3A4 |
| D07298 |
Barbexaclone (INN); Maliasin (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ |
| D07307 |
Cyamemazine (INN); Tercian (TN) |
(P) unclassified |
| D07308 |
Chlorproethazine (INN) |
(P) unclassified |
| D07321 |
Vinylbital (INN); Vinylbitone |
(P) unclassified |
| D07322 |
Vinbarbital (INN) |
(P) unclassified |
| D07323 |
Cyclobarbital (INN); Ciclobarbital (TN) |
(P) unclassified |
| D07324 |
Proxibarbal (INN); Centralgol (TN) |
(P) unclassified |
| D07337 |
Nialamide (INN); Niamid (TN) |
(P) unclassified |
| D07338 |
Iproclozide (INN); Iproclozide (TN) |
(P) unclassified |
| D07523 |
Betaine (JAN); Cystadane (TN) |
(P) unclassified |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) Enzyme: CYP2C9 |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP3A4 |
| D07685 |
Chlorproethazine hydrochloride; Neuriplege (TN) |
(P) unclassified |
| D07756 |
Cyamemazine tartrate; Tercian (TN) |
(P) unclassified |
| D07757 |
Cyclobarbital calcium (BAN); Phanodorn calcium (TN) |
(P) unclassified |
| D07865 |
Dixyrazine; Esucos (TN) |
(P) unclassified |
| D07977 |
Fluphenazine (INN); Moditen (TN) |
(P) unclassified |
| D08085 |
Iproniazid phosphate; Marsilid (TN) |
(P) unclassified |
| D08341 |
Perphenazine decanoate; Trilafon dekanoat (TN) |
(P) unclassified |
| D08342 |
Perphenazine enantate; Perphenazine enanthate; Trilafon (TN) |
(P) unclassified |
| D08349 |
Phenelzine (BAN) |
(P) unclassified |
| D08356 |
Phenobarbital diethylamine; Gratusminal (TN) |
(P) Target: GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ / CYP induction: CYP2C9 |
| D08385 |
Pipotiazine (INN); Piportil (TN) |
(P) unclassified |
| D08392 |
Pirlindole (INN); Pyrazidol (TN) |
(P) unclassified |
| D08393 |
Pirlindole hydrochloride; Implementor (TN) |
(P) unclassified |
| D08430 |
Promazine (INN); Combelen [veterinary] (TN) |
(P) unclassified |
| D08453 |
Pargyline (INN) |
(P) unclassified |
| D08469 |
Rasagiline (USAN/INN); Azilect (TN) |
(P) unclassified |
| D08585 |
Thioproperazine (INN) |
(P) unclassified |
| D08625 |
Tranylcypromine (INN); Parnate (TN) |
(P) unclassified |
| D08636 |
Trifluoperazine (INN); Apo-trifluoperazine (TN) |
(P) unclassified |
| D09216 |
Thiopropazate (INN) |
(P) unclassified |
| D09594 |
Olmesartan medoxomil and azelnidipine; Rezaltas (TN) |
(P) Enzyme: CYP3A4 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09773 |
Isoniazid glucuronate sodium (JAN) |
(P) unclassified |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09819 |
Chlorpromazine tannate (JAN) |
(P) unclassified |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP inhibition: CYP2C9 / CYP induction: CYP3A4 |
| D09999 |
Tramadol hydrochloride and acetaminophen; Tramcet (TN) |
(P) Enzyme: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10012 |
Incobotulinumtoxin A (JAN/USAN); Onaclostox; Xeomin (TN) |
(P) unclassified |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D10158 |
Safinamide (USAN/INN) |
(P) unclassified |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10191 |
Safinamide mesylate (USAN); Safinamide mesilate (JAN); Safinamide methanesulfonate; Xadago (TN); Equfina (TN) |
(P) unclassified |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP3A4 |
| D10519 |
Rabeprazole, amoxicillin and clarithromycin; Rabecure (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) CYP inhibition: CYP2C9 |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP3A4 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) CYP induction: CYP2C9 |
| D10829 |
Rasagiline tartrate; Rasagiline (TN) |
(P) unclassified |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11404 |
Asciminib hydrochloride (JAN/USAN); Scemblix (TN) |
(P) Enzyme: CYP3A4 |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) unclassified |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
