<?xml version="1.0"?>
<!DOCTYPE pathway SYSTEM "http://www.genome.jp/kegg/xml/KGML_v0.7.1_.dtd">
<!-- Creation date: May 16, 2011 18:56:01 +0900 (GMT+09:00) -->
<pathway name="path:hsa05014" org="hsa" number="05014"
         title="Amyotrophic lateral sclerosis (ALS)"
         image="http://www.genome.jp/kegg/pathway/hsa/hsa05014.png"
         link="http://www.genome.jp/kegg-bin/show_pathway?hsa05014">
    <entry id="1" name="hsa:6647" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:6647">
        <graphics name="SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="790" y="757" width="46" height="17"/>
    </entry>
    <entry id="2" name="hsa:6506" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:6506">
        <graphics name="SLC1A2, EAAT2, GLT-1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="188" y="306" width="46" height="17"/>
    </entry>
    <entry id="3" name="path:hsa05014" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa05014">
        <graphics name="TITLE:Amyotrophic lateral sclerosis (ALS)" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="204" y="58" width="327" height="25"/>
    </entry>
    <entry id="4" name="hsa:2890 hsa:2891 hsa:2902 hsa:2903 hsa:2904 hsa:2905 hsa:2906" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:2890+hsa:2891+hsa:2902+hsa:2903+hsa:2904+hsa:2905+hsa:2906">
        <graphics name="GRIA1, GLUH1, GLUR1, GLURA, GluA1, HBGR1..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="330" y="549" width="46" height="17"/>
    </entry>
    <entry id="5" name="hsa:10452 hsa:84134" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:10452+hsa:84134">
        <graphics name="TOMM40, C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="684" y="329" width="46" height="17"/>
    </entry>
    <entry id="6" name="hsa:6647" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:6647">
        <graphics name="SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="556" y="276" width="46" height="17"/>
    </entry>
    <entry id="7" name="hsa:54205" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:54205">
        <graphics name="CYCS, CYC, HCS, THC4" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="874" y="97" width="46" height="17"/>
    </entry>
    <entry id="8" name="cpd:C00025" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00025">
        <graphics name="C00025" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="256" y="517" width="8" height="8"/>
    </entry>
    <entry id="9" name="path:hsa04210" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa04210">
        <graphics name="Apoptosis" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="1020" y="109" width="109" height="25"/>
    </entry>
    <entry id="10" name="hsa:7124" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:7124">
        <graphics name="TNF, DIF, TNF-alpha, TNFA, TNFSF2" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="251" y="726" width="46" height="17"/>
    </entry>
    <entry id="11" name="cpd:C00533" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00533">
        <graphics name="C00533" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="256" y="782" width="8" height="8"/>
    </entry>
    <entry id="12" name="hsa:834" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:834">
        <graphics name="CASP1, ICE, IL1BC, P45" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="502" y="239" width="46" height="17"/>
    </entry>
    <entry id="13" name="hsa:836" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:836">
        <graphics name="CASP3, CPP32, CPP32B, SCA-1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="1068" y="77" width="46" height="17"/>
    </entry>
    <entry id="14" name="hsa:581" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:581">
        <graphics name="BAX, BCL2L4" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="930" y="198" width="46" height="17"/>
    </entry>
    <entry id="15" name="hsa:572" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:572">
        <graphics name="BAD, BBC2, BCL2L8" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="982" y="198" width="46" height="17"/>
    </entry>
    <entry id="16" name="hsa:596" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:596">
        <graphics name="BCL2, Bcl-2, PPP1R50" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="760" y="199" width="46" height="17"/>
    </entry>
    <entry id="17" name="hsa:598" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:598">
        <graphics name="BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="812" y="199" width="46" height="17"/>
    </entry>
    <entry id="18" name="path:hsa03050" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa03050">
        <graphics name="Proteasome" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="692" y="467" width="109" height="25"/>
    </entry>
    <entry id="19" name="hsa:317" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:317">
        <graphics name="APAF1, APAF-1, CED4" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="875" y="55" width="46" height="17"/>
    </entry>
    <entry id="20" name="hsa:842" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:842">
        <graphics name="CASP9, APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6, PPP1R56" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="982" y="76" width="46" height="17"/>
    </entry>
    <entry id="21" name="cpd:C00076" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00076">
        <graphics name="C00076" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="393" y="549" width="8" height="8"/>
    </entry>
    <entry id="22" name="hsa:637" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:637">
        <graphics name="BID, FP497" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="619" y="238" width="46" height="17"/>
    </entry>
    <entry id="23" name="cpd:C00533" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00533">
        <graphics name="C00533" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="248" y="211" width="8" height="8"/>
    </entry>
    <entry id="24" name="hsa:7132 hsa:7133" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:7132+hsa:7133">
        <graphics name="TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="331" y="726" width="46" height="17"/>
    </entry>
    <entry id="25" name="hsa:1616" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:1616">
        <graphics name="DAXX, BING2, DAP6, EAP1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="554" y="630" width="46" height="17"/>
    </entry>
    <entry id="26" name="hsa:4217" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4217">
        <graphics name="MAP3K5, ASK1, MAPKKK5, MEKK5" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="644" y="630" width="46" height="17"/>
    </entry>
    <entry id="27" name="hsa:5606" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:5606">
        <graphics name="MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="737" y="618" width="46" height="17"/>
    </entry>
    <entry id="28" name="hsa:5608" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:5608">
        <graphics name="MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="737" y="642" width="46" height="17"/>
    </entry>
    <entry id="29" name="hsa:1432 hsa:5600 hsa:5603 hsa:6300" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:1432+hsa:5600+hsa:5603+hsa:6300">
        <graphics name="MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="830" y="630" width="46" height="17"/>
    </entry>
    <entry id="30" name="path:hsa04010" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa04010">
        <graphics name="MAPK signaling pathway" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="939" y="605" width="109" height="34"/>
    </entry>
    <entry id="31" name="hsa:4747" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4747">
        <graphics name="NEFL, CMT1F, CMT2E, NF-L, NF68, NFL" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="902" y="776" width="46" height="17"/>
    </entry>
    <entry id="32" name="hsa:4741" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4741">
        <graphics name="NEFM, NEF3, NF-M, NFM" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="902" y="802" width="46" height="17"/>
    </entry>
    <entry id="33" name="hsa:4744" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4744">
        <graphics name="NEFH, NFH" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="902" y="827" width="46" height="17"/>
    </entry>
    <entry id="34" name="hsa:5630 hsa:5961" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:5630+hsa:5961">
        <graphics name="PRPH, NEF4, PRPH1..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="860" y="850" width="46" height="17"/>
    </entry>
    <entry id="35" name="hsa:6647" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:6647">
        <graphics name="SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="669" y="817" width="46" height="17"/>
    </entry>
    <entry id="36" name="hsa:6647" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:6647">
        <graphics name="SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="764" y="817" width="46" height="17"/>
    </entry>
    <entry id="37" name="hsa:2876" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:2876">
        <graphics name="GPX1, GPXD, GSHPX1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="759" y="849" width="46" height="17"/>
    </entry>
    <entry id="38" name="hsa:847" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:847">
        <graphics name="CAT" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="759" y="872" width="46" height="17"/>
    </entry>
    <entry id="39" name="hsa:4842" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4842">
        <graphics name="NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="591" y="708" width="46" height="17"/>
    </entry>
    <entry id="40" name="hsa:9973" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:9973">
        <graphics name="CCS" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="642" y="855" width="46" height="17"/>
    </entry>
    <entry id="42" name="cpd:C00062" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00062">
        <graphics name="C00062" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="557" y="724" width="8" height="8"/>
    </entry>
    <entry id="43" name="cpd:C00533" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00533">
        <graphics name="C00533" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="629" y="724" width="8" height="8"/>
    </entry>
    <entry id="44" name="cpd:C16845" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C16845">
        <graphics name="C16845" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="717" y="725" width="8" height="8"/>
    </entry>
    <entry id="45" name="cpd:C00704" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00704">
        <graphics name="C00704" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="628" y="801" width="8" height="8"/>
    </entry>
    <entry id="46" name="cpd:C00027" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00027">
        <graphics name="C00027" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="720" y="802" width="8" height="8"/>
    </entry>
    <entry id="47" name="cpd:C16844" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C16844">
        <graphics name="C16844" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="819" y="803" width="8" height="8"/>
    </entry>
    <entry id="48" name="cpd:C00070" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00070">
        <graphics name="C00070" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="617" y="877" width="8" height="8"/>
    </entry>
    <entry id="49" name="cpd:C00001" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00001">
        <graphics name="C00001" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="817" y="878" width="8" height="8"/>
    </entry>
    <entry id="50" name="hsa:57679" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:57679">
        <graphics name="ALS2, ALS2CR6, ALSJ, IAHSP, PLSJ" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="996" y="840" width="46" height="17"/>
    </entry>
    <entry id="51" name="hsa:79139" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:79139">
        <graphics name="DERL1, DER-1, DER1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="612" y="529" width="46" height="17"/>
    </entry>
    <entry id="52" name="hsa:5879" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:5879">
        <graphics name="RAC1, Rac-1, TC-25, p21-Rac1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="1020" y="874" width="46" height="17"/>
    </entry>
    <entry id="53" name="hsa:5868" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:5868">
        <graphics name="RAB5A, RAB5" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="1080" y="839" width="46" height="17"/>
    </entry>
    <entry id="54" name="hsa:11261 hsa:5530 hsa:5532 hsa:5533 hsa:5534 hsa:5535 hsa:63928" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:11261+hsa:5530+hsa:5532+hsa:5533+hsa:5534+hsa:5535+hsa:63928">
        <graphics name="CHP1, CHP, SLC9A1BP, Sid470p, p22, p24..." fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="642" y="183" width="46" height="17"/>
    </entry>
    <entry id="55" name="hsa:7157" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:7157">
        <graphics name="TP53, BCC7, LFS1, P53, TRP53" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="677" y="137" width="46" height="17"/>
    </entry>
    <entry id="56" name="path:hsa04115" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa04115">
        <graphics name="p53 signaling pathway" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="684" y="102" width="109" height="34"/>
    </entry>
    <entry id="57" name="cpd:C00076" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00076">
        <graphics name="C00076" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="740" y="357" width="8" height="8"/>
    </entry>
    <entry id="58" name="cpd:C00076" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00076">
        <graphics name="C00076" fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="785" y="558" width="8" height="8"/>
    </entry>
    <entry id="59" name="cpd:C00704 cpd:C00027 cpd:C16845 cpd:C16844" type="compound"
        link="http://www.kegg.jp/dbget-bin/www_bget?C00704+C00027+C16845+C16844">
        <graphics name="C00704..." fgcolor="#000000" bgcolor="#FFFFFF"
             type="circle" x="379" y="240" width="8" height="8"/>
    </entry>
    <entry id="60" name="hsa:100506742" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:100506742">
        <graphics name="CASP12, CASP-12, CASP12P1" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="941" y="516" width="46" height="17"/>
    </entry>
    <entry id="61" name="hsa:4217" type="gene"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa:4217">
        <graphics name="MAP3K5, ASK1, MAPKKK5, MEKK5" fgcolor="#000000" bgcolor="#BFFFBF"
             type="rectangle" x="941" y="551" width="46" height="17"/>
    </entry>
    <entry id="62" name="path:hsa04210" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa04210">
        <graphics name="Apoptosis" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="1036" y="496" width="109" height="25"/>
    </entry>
    <entry id="63" name="path:hsa04724" type="map"
        link="http://www.kegg.jp/dbget-bin/www_bget?hsa04724">
        <graphics name="Glutamatergic synapse" fgcolor="#000000" bgcolor="#FFFFFF"
             type="roundrectangle" x="258" y="607" width="92" height="34"/>
    </entry>
    <relation entry1="19" entry2="20" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="7" entry2="20" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="20" entry2="13" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="6" entry2="59" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="10" entry2="24" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="24" entry2="25" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="25" entry2="26" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="26" entry2="27" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="26" entry2="28" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="27" entry2="29" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="28" entry2="29" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="50" entry2="53" type="PPrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="50" entry2="52" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="59" entry2="2" type="PCrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="59" entry2="54" type="PCrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="6" entry2="16" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="6" entry2="5" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="6" entry2="51" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="6" entry2="54" type="PPrel">
        <subtype name="missing interaction" value="-/-"/>
    </relation>
    <relation entry1="16" entry2="7" type="PPrel">
        <subtype name="missing interaction" value="-/-"/>
    </relation>
    <relation entry1="17" entry2="7" type="PPrel">
        <subtype name="missing interaction" value="-/-"/>
    </relation>
    <relation entry1="14" entry2="7" type="PPrel">
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="15" entry2="7" type="PPrel">
        <subtype name="indirect effect" value="..&gt;"/>
    </relation>
    <relation entry1="8" entry2="4" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="48" entry2="35" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="39" entry2="43" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="35" entry2="46" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="36" entry2="47" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="37" entry2="49" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="38" entry2="49" type="PCrel">
        <subtype name="activation" value="--&gt;"/>
    </relation>
    <relation entry1="34" entry2="31" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="34" entry2="32" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="34" entry2="33" type="PPrel">
        <subtype name="binding/association" value="---"/>
    </relation>
    <relation entry1="1" entry2="31" type="PPrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="29" entry2="31" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="29" entry2="32" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="29" entry2="33" type="PPrel">
        <subtype name="phosphorylation" value="+p"/>
    </relation>
    <relation entry1="47" entry2="31" type="PCrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="47" entry2="32" type="PCrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
    <relation entry1="47" entry2="33" type="PCrel">
        <subtype name="inhibition" value="--|"/>
    </relation>
</pathway>
