+E	Module
#<h2><a href="/kegg/kegg2.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; KEGG Modules</h2>
#<!---
#ENTRY       ko00002
#NAME        Module
#DEFINITION  KEGG modules
#--->
!
A<b>Pathway module</b>
B
B  <b>Energy metabolism</b>
C    Carbon fixation
D      M00165  Reductive pentose phosphate cycle (Calvin cycle) [PATH:map00710]
E        K01601  rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
E        K01602  rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
E        K00927  PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
E        K05298  GAPA; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) [EC:1.2.1.13]
E        K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
E        K01623  ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
E        K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
E        K02446  glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
E        K11532  glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
E        K04041  fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11]
E        K00615  E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]
E        K01100  E3.1.3.37; sedoheptulose-bisphosphatase [EC:3.1.3.37]
E        K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
E        K01808  rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
E        K00855  E2.7.1.19, prkB; phosphoribulokinase [EC:2.7.1.19]
D      M00166  Reductive pentose phosphate cycle, RuBP + CO2 => glyceraldehyde-3P [PATH:map00710]
E        K01601  rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
E        K01602  rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
E        K00927  PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
E        K05298  GAPA; glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) [EC:1.2.1.13]
E        K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
D      M00167  Reductive pentose phosphate cycle, glyceraldehyde-3P => RuBP [PATH:map00710]
E        K01623  ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
E        K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
E        K02446  glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
E        K11532  glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
E        K04041  fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11]
E        K00615  E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]
E        K01100  E3.1.3.37; sedoheptulose-bisphosphatase [EC:3.1.3.37]
E        K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
E        K01808  rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
E        K00855  E2.7.1.19, prkB; phosphoribulokinase [EC:2.7.1.19]
D      M00168  CAM (Crassulacean acid metabolism), dark [PATH:map00710]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
E        K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
D      M00169  CAM (Crassulacean acid metabolism), light [PATH:map00710]
E        K00029  E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
E        K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]
D      M00170  C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type [PATH:map00710]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K14454  GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
E        K01610  E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D      M00171  C4-dicarboxylic acid cycle, NAD+ -malic enzyme type [PATH:map00710]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K14454  GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
E        K14455  GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
E        K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
E        K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
E        K00028  E1.1.1.39; malate dehydrogenase (decarboxylating) [EC:1.1.1.39]
E        K00814  GPT, ALT; alanine transaminase [EC:2.6.1.2]
E        K14272  GGAT; glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44 2.6.1.-]
E        K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]
D      M00172  C4-dicarboxylic acid cycle, NADP+ -malic enzyme type [PATH:map00710]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K00051  E1.1.1.82; malate dehydrogenase (NADP+) [EC:1.1.1.82]
E        K00029  E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
E        K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]
D      M00173  Reductive citric acid cycle (Arnon-Buchanan cycle) [PATH:map00720]
E        K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
E        K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
E        K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
E        K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
E        K03737  nifJ; putative pyruvate-flavodoxin oxidoreductase [EC:1.2.7.-]
E        K01007  pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]
E        K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K01959  E6.4.1.1A, pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
E        K01960  E6.4.1.1B, pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
E        K01958  PC, pyc; pyruvate carboxylase [EC:6.4.1.1]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
E        K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
E        K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
E        K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
E        K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
E        K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
E        K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
E        K00174  korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3]
E        K00175  korB; 2-oxoglutarate ferredoxin oxidoreductase subunit beta [EC:1.2.7.3]
E        K00177  korG; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
E        K00176  korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
E        K00031  IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01682  acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
E        K15230  aclA; ATP-citrate lyase alpha-subunit [EC:2.3.3.8]
E        K15231  aclB; ATP-citrate lyase beta-subunit [EC:2.3.3.8]
E        K15232  ccsA; citryl-CoA synthetase large subunit [EC:6.2.1.18]
E        K15233  ccsB; citryl-CoA synthetase small subunit
E        K15234  ccl; citryl-CoA lyase [EC:4.1.3.34]
D      M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway) [PATH:map00720]
E        K00198  cooS, acsA; carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.99.2 1.2.7.4]
E        K05299  E1.2.1.43A, fdhA; formate dehydrogenase alpha subunit [EC:1.2.1.43]
E        K15022  fdhB; formate dehydrogenase beta subunit [EC:1.2.1.43]
E        K01938  fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
E        K01491  folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
E        K00297  metF, MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
E        K15023  acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
E        K14138  acsB; acetyl-CoA synthase [EC:2.3.1.169]
E        K00197  cdhE, acsC; acetyl-CoA decarbonylase/synthase complex subunit gamma [EC:2.1.1.245]
E        K00194  cdhD, acsD; acetyl-CoA decarbonylase/synthase complex subunit delta [EC:2.1.1.245]
D      M00376  3-Hydroxypropionate bicycle [PATH:map00720]
E        K02160  accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein
E        K01961  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
E        K01962  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
E        K01963  accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
E        K01964  K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
E        K15037  K15037; biotin carboxyl carrier protein
E        K15036  K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
E        K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.2.1.75 1.1.1.298]
E        K15017  K15017; succinyl-CoA reductase (NADPH) [EC:1.2.1.-]
E        K15039  K15039; 3-hydroxypropionate dehydrogenase (NADP+)
E        K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
E        K15018  K15018; 3-hydroxypropionyl-coenzyme A synthetase [EC:6.2.1.36]
E        K15019  K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116]
E        K15020  K15020; acryloyl-coenzyme A reductase [EC:1.3.1.84]
E        K01965  PCCA, pccA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
E        K01966  PCCB, pccB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3]
E        K15052  K15052; propionyl-CoA carboxylase [EC:6.4.1.3]
E        K05606  MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
E        K01847  MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
E        K01848  E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
E        K01849  E5.4.99.2B, mcmA2; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
E        K11942  E5.4.99.2; methylmalonyl-CoA mutase [EC:5.4.99.2]
E        K14471  K14471, smtA; succinyl-CoA:(S)- malate CoA transferase subunit A [EC:2.8.3.-]
E        K14472  smtB; succinyl-CoA:(S)- malate CoA transferase subunit B [EC:2.8.3.-]
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
E        K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
E        K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
E        K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
E        K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
E        K08691  mcl; malyl-CoA lyase [EC:4.1.3.24]
E        K14449  K14449, mch; mesaconyl-CoA hydratase
E        K14470  mct; mesaconyl-CoA C1-C4 CoA transferase
E        K09709  meh; mesaconyl-C4 CoA hydratase
D      M00375  Hydroxypropionate-hydroxybutylate cycle [PATH:map00720]
E        K02160  accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein
E        K01961  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
E        K01962  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
E        K01963  accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
E        K01964  K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
E        K15037  K15037; biotin carboxyl carrier protein
E        K15036  K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
E        K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.2.1.75 1.1.1.298]
E        K15017  K15017; succinyl-CoA reductase (NADPH) [EC:1.2.1.-]
E        K15039  K15039; 3-hydroxypropionate dehydrogenase (NADP+)
E        K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]
E        K15018  K15018; 3-hydroxypropionyl-coenzyme A synthetase [EC:6.2.1.36]
E        K15019  K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116]
E        K15020  K15020; acryloyl-coenzyme A reductase [EC:1.3.1.84]
E        K01965  PCCA, pccA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
E        K01966  PCCB, pccB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3]
E        K15052  K15052; propionyl-CoA carboxylase [EC:6.4.1.3]
E        K05606  MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
E        K01847  MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
E        K01848  E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
E        K01849  E5.4.99.2B, mcmA2; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
E        K11942  E5.4.99.2; methylmalonyl-CoA mutase [EC:5.4.99.2]
E        K15038  K15038; succinyl-coA reductase [EC:1.2.1.76]
E        K14465  K14465; succinate semialdehyde reductase (NADPH) [EC:1.1.1.-]
E        K14466  K14466; 4-hydroxybutyryl-CoA synthetase (4-hydroxybutyrate-CoA ligase, AMP-forming) [EC:6.2.1.-]
E        K14467  K14467; 4-hydroxybutyryl&#8211;CoA synthetase (4-hydroxybutyrate&#8211;CoA ligase, AMP-forming) [EC:6.2.1.-]
E        K14534  abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
E        K15016  K15016; 3-hydroxybutyryl-CoA dehydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.55 1.1.1.35]
E        K01715  crt; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
E        K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
E        K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
E        K07516  fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
E        K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      M00374  Dicarboxylate-hydroxybutyrate cycle [PATH:map00720]
E        K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
E        K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
E        K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
E        K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
E        K03737  nifJ; putative pyruvate-flavodoxin oxidoreductase [EC:1.2.7.-]
E        K01007  pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
E        K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
E        K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
E        K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
E        K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
E        K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
E        K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
E        K15038  K15038; succinyl-coA reductase [EC:1.2.1.76]
E        K14465  K14465; succinate semialdehyde reductase (NADPH) [EC:1.1.1.-]
E        K14466  K14466; 4-hydroxybutyryl-CoA synthetase (4-hydroxybutyrate-CoA ligase, AMP-forming) [EC:6.2.1.-]
E        K14467  K14467; 4-hydroxybutyryl&#8211;CoA synthetase (4-hydroxybutyrate&#8211;CoA ligase, AMP-forming) [EC:6.2.1.-]
E        K14534  abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
E        K15016  K15016; 3-hydroxybutyryl-CoA dehydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.55 1.1.1.35]
E        K01715  crt; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
E        K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
E        K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
E        K07516  fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
E        K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:map00720]
E        K00625  E2.3.1.8, pta; phosphate acetyltransferase [EC:2.3.1.8]
E        K13788  pta; phosphate acetyltransferase [EC:2.3.1.8]
E        K15024  K15024; propanediol utilization protein
E        K00925  ackA; acetate kinase [EC:2.7.2.1]
C    Nitrogen metabolism
D      M00175  Nitrogen fixation, nitrogen => ammonia [PATH:map00910]
E        K00531  anfG; nitrogenase [EC:1.18.6.1]
E        K02586  nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
E        K02591  nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
E        K02588  nifH; nitrogenase iron protein NifH [EC:1.18.6.1]
E        K02595  nifW; nitrogenase-stabilizing/protective protein
D      M00531  Assimilatory nitrate reduction, nitrate => ammonia [PATH:map00910]
E        K00367  narB; ferredoxin-nitrate reductase [EC:1.7.7.2]
E        K00360  E1.7.1.1; nitrate reductase (NADH) [EC:1.7.1.1]
E        K15875  NAR; nitrate reductase [NAD(P)H] [EC:1.7.1.2]
E        K10534  NIAD; nitrate reductase (NADPH) [EC:1.7.1.3]
E        K00372  E1.7.99.4C; nitrate reductase catalytic subunit [EC:1.7.99.4]
E        K00362  nirB; nitrite reductase (NAD(P)H) large subunit [EC:1.7.1.4]
E        K00363  nirD; nitrite reductase (NAD(P)H) small subunit [EC:1.7.1.4]
E        K00366  nirA; ferredoxin-nitrite reductase [EC:1.7.7.1]
D      M00530  Dissimilatory nitrate reduction, nitrate => ammonia [PATH:map00910]
E        K00370  narG; nitrate reductase 1, alpha subunit [EC:1.7.99.4]
E        K00371  narH; nitrate reductase 1, beta subunit [EC:1.7.99.4]
E        K00374  narI; nitrate reductase 1, gamma subunit [EC:1.7.99.4]
E        K00373  narJ; nitrate reductase 1, delta subunit
E        K15878  K15878, narB; rieske iron-sulphur protein
E        K15879  narC; cytochrome b-561
E        K08345  narZ; nitrate reductase 2, alpha subunit [EC:1.7.99.4]
E        K08346  narY; nitrate reductase 2, beta subunit [EC:1.7.99.4]
E        K08347  narV; nitrate reductase 2, gamma subunit [EC:1.7.99.4]
E        K08361  narW; nitrate reductase 2, delta subunit
E        K02567  napA; periplasmic nitrate reductase NapA [EC:1.7.99.4]
E        K02568  napB; cytochrome c-type protein NapB
E        K00362  nirB; nitrite reductase (NAD(P)H) large subunit [EC:1.7.1.4]
E        K00363  nirD; nitrite reductase (NAD(P)H) small subunit [EC:1.7.1.4]
E        K00366  nirA; ferredoxin-nitrite reductase [EC:1.7.7.1]
E        K03385  nrfA; cytochrome c-552 [EC:1.7.2.2]
E        K15876  nrfH; cytochrome c-type protein
D      M00529  Denitrification, nitrate => nitrogen [PATH:map00910]
E        K00370  narG; nitrate reductase 1, alpha subunit [EC:1.7.99.4]
E        K00371  narH; nitrate reductase 1, beta subunit [EC:1.7.99.4]
E        K00374  narI; nitrate reductase 1, gamma subunit [EC:1.7.99.4]
E        K00373  narJ; nitrate reductase 1, delta subunit
E        K15878  K15878, narB; rieske iron-sulphur protein
E        K15879  narC; cytochrome b-561
E        K08345  narZ; nitrate reductase 2, alpha subunit [EC:1.7.99.4]
E        K08346  narY; nitrate reductase 2, beta subunit [EC:1.7.99.4]
E        K08347  narV; nitrate reductase 2, gamma subunit [EC:1.7.99.4]
E        K08361  narW; nitrate reductase 2, delta subunit
E        K02567  napA; periplasmic nitrate reductase NapA [EC:1.7.99.4]
E        K02568  napB; cytochrome c-type protein NapB
E        K00368  E1.7.2.1; nitrite reductase (NO-forming) [EC:1.7.2.1]
E        K15864  nirS; nitrite reductase (NO-forming) / hydroxylamine reductase [EC:1.7.2.1 1.7.99.1]
E        K04561  norB; nitric oxide reductase subunit B [EC:1.7.2.5]
E        K02305  norC; nitric oxide reductase subunit C
E        K15877  CYP55; fungal nitric oxide reductase [EC:1.7.1.14]
E        K00376  nosZ; nitrous-oxide reductase [EC:1.7.2.4]
D      M00528  Nitrification, ammonia => nitrite [PATH:map00910]
E        K10944  amoA; ammonia monooxygenase subunit A [EC:1.14.99.39]
E        K10945  amoB; ammonia monooxygenase subunit B
E        K10946  amoC; ammonia monooxygenase subunit C
E        K10535  hao; hydroxylamine dehydrogenase [EC:1.7.2.6]
C    Methane metabolism
D      M00347  Methanogenesis, formate => methane [PATH:map00680]
E        K00123  E1.2.1.2A; formate dehydrogenase, alpha subunit [EC:1.2.1.2]
E        K00125  E1.2.1.2B2; formate dehydrogenase, beta subunit [EC:1.2.1.2]
E        K00124  E1.2.1.2B1; formate dehydrogenase, beta subunit
E        K00126  E1.2.1.2D, fdsD; formate dehydrogenase, delta subunit [EC:1.2.1.2]
E        K00127  E1.2.1.2G; formate dehydrogenase, gamma subunit
E        K00200  E1.2.99.5A, fwdA, fmdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.99.5]
E        K00201  E1.2.99.5B, fwdB, fmdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.99.5]
E        K00202  E1.2.99.5C, fwdC, fmdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.99.5]
E        K00203  E1.2.99.5D, fwdD, fmdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.99.5]
E        K00204  E1.2.99.5H, fwdH; formylmethanofuran dehydrogenase subunit H [EC:1.2.99.5]
E        K00205  E1.2.99.5F, fwdF, fmdF; formylmethanofuran dehydrogenase subunit F [EC:1.2.99.5]
E        K11261  E1.2.99.5E, fmdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.99.5]
E        K11260  E1.2.99.5G, fwdG; formylmethanofuran dehydrogenase subunit G [EC:1.2.99.5]
E        K00672  E2.3.1.101, ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
E        K01499  mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
E        K00319  mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.99.9]
E        K13942  hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2]
E        K00320  mer; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [EC:1.5.99.11]
E        K00440  frhA; coenzyme F420 hydrogenase alpha subunit [EC:1.12.98.1]
E        K00441  frhB; coenzyme F420 hydrogenase beta subunit [EC:1.12.98.1]
E        K00442  frhD; coenzyme F420 hydrogenase delta subunit
E        K00443  frhG; coenzyme F420 hydrogenase gamma subunit [EC:1.12.98.1]
E        K00577  E2.1.1.86A, mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:2.1.1.86]
E        K00578  E2.1.1.86B, mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:2.1.1.86]
E        K00579  mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:2.1.1.86]
E        K00580  mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:2.1.1.86]
E        K00581  mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:2.1.1.86]
E        K00582  mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:2.1.1.86]
E        K00583  mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:2.1.1.86]
E        K00584  mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:2.1.1.86]
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00567  Methanogenesis, CO2 => methane [PATH:map00680]
E        K00200  E1.2.99.5A, fwdA, fmdA; formylmethanofuran dehydrogenase subunit A [EC:1.2.99.5]
E        K00201  E1.2.99.5B, fwdB, fmdB; formylmethanofuran dehydrogenase subunit B [EC:1.2.99.5]
E        K00202  E1.2.99.5C, fwdC, fmdC; formylmethanofuran dehydrogenase subunit C [EC:1.2.99.5]
E        K00203  E1.2.99.5D, fwdD, fmdD; formylmethanofuran dehydrogenase subunit D [EC:1.2.99.5]
E        K00204  E1.2.99.5H, fwdH; formylmethanofuran dehydrogenase subunit H [EC:1.2.99.5]
E        K00205  E1.2.99.5F, fwdF, fmdF; formylmethanofuran dehydrogenase subunit F [EC:1.2.99.5]
E        K11261  E1.2.99.5E, fmdE; formylmethanofuran dehydrogenase subunit E [EC:1.2.99.5]
E        K11260  E1.2.99.5G, fwdG; formylmethanofuran dehydrogenase subunit G [EC:1.2.99.5]
E        K00672  E2.3.1.101, ftr; formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101]
E        K01499  mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
E        K00319  mtd; methylenetetrahydromethanopterin dehydrogenase [EC:1.5.99.9]
E        K13942  hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2]
E        K00320  mer; coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [EC:1.5.99.11]
E        K00440  frhA; coenzyme F420 hydrogenase alpha subunit [EC:1.12.98.1]
E        K00441  frhB; coenzyme F420 hydrogenase beta subunit [EC:1.12.98.1]
E        K00442  frhD; coenzyme F420 hydrogenase delta subunit
E        K00443  frhG; coenzyme F420 hydrogenase gamma subunit [EC:1.12.98.1]
E        K00577  E2.1.1.86A, mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:2.1.1.86]
E        K00578  E2.1.1.86B, mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:2.1.1.86]
E        K00579  mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:2.1.1.86]
E        K00580  mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:2.1.1.86]
E        K00581  mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:2.1.1.86]
E        K00582  mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:2.1.1.86]
E        K00583  mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:2.1.1.86]
E        K00584  mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:2.1.1.86]
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00356  Methanogenesis, methanol => methane [PATH:map00680]
E        K14080  mtaA; [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.246]
E        K04480  mtaB; methanol---5-hydroxybenzimidazolylcobamide Co-methyltransferase [EC:2.1.1.90]
E        K14081  mtaC; methanol corrinoid protein
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00357  Methanogenesis, acetate => methane [PATH:map00680]
E        K00925  ackA; acetate kinase [EC:2.7.2.1]
E        K00625  E2.3.1.8, pta; phosphate acetyltransferase [EC:2.3.1.8]
E        K13788  pta; phosphate acetyltransferase [EC:2.3.1.8]
E        K01895  ACSS, acs; acetyl-CoA synthetase [EC:6.2.1.1]
E        K00193  cdhC; acetyl-CoA decarbonylase/synthase complex subunit beta [EC:2.3.1.-]
E        K00197  cdhE, acsC; acetyl-CoA decarbonylase/synthase complex subunit gamma [EC:2.1.1.245]
E        K00194  cdhD, acsD; acetyl-CoA decarbonylase/synthase complex subunit delta [EC:2.1.1.245]
E        K00577  E2.1.1.86A, mtrA; tetrahydromethanopterin S-methyltransferase subunit A [EC:2.1.1.86]
E        K00578  E2.1.1.86B, mtrB; tetrahydromethanopterin S-methyltransferase subunit B [EC:2.1.1.86]
E        K00579  mtrC; tetrahydromethanopterin S-methyltransferase subunit C [EC:2.1.1.86]
E        K00580  mtrD; tetrahydromethanopterin S-methyltransferase subunit D [EC:2.1.1.86]
E        K00581  mtrE; tetrahydromethanopterin S-methyltransferase subunit E [EC:2.1.1.86]
E        K00582  mtrF; tetrahydromethanopterin S-methyltransferase subunit F [EC:2.1.1.86]
E        K00583  mtrG; tetrahydromethanopterin S-methyltransferase subunit G [EC:2.1.1.86]
E        K00584  mtrH; tetrahydromethanopterin S-methyltransferase subunit H [EC:2.1.1.86]
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00563  Methanogenesis, methylamine => methane [PATH:map00680]
E        K14082  mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
E        K16176  mtmB; methylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.248]
E        K16177  mtmC; monomethylamine corrinoid protein
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00562  Methanogenesis, dimethylamine => methane [PATH:map00680]
E        K14082  mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
E        K16178  mtbB; dimethylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.249]
E        K16179  mtbC; dimethylamine corrinoid protein
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00561  Methanogenesis, trimethylamine => methane [PATH:map00680]
E        K14082  mtbA; [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase [EC:2.1.1.247]
E        K14083  mttB; trimethylamine---corrinoid protein Co-methyltransferase [EC:2.1.1.250]
E        K14084  mttC; trimethylamine corrinoid protein
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
E        K03388  hdrA; heterodisulfide reductase subunit A [EC:1.8.98.1]
E        K03389  hdrB; heterodisulfide reductase subunit B [EC:1.8.98.1]
E        K03390  hdrC; heterodisulfide reductase subunit C [EC:1.8.98.1]
D      M00358  Coenzyme M biosynthesis [PATH:map00680]
E        K08097  E4.4.1.19, comA; phosphosulfolactate synthase [EC:4.4.1.19]
E        K05979  E3.1.3.71, comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71]
E        K05884  E1.1.1.272; (R)-2-hydroxyacid dehydrogenase [EC:1.1.1.272]
E        K13039  K13039, comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]
E        K06034  K06034, comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]
D      M00174  Methane oxidation, methylotroph, methane => CO2 [PATH:map00680]
E        K16154  pmoA; methane monooxygenase subunit A [EC:1.14.13.25]
E        K16155  pmoB; methane monooxygenase subunit B [EC:1.14.13.25]
E        K16156  pmoC; methane monooxygenase subunit C [EC:1.14.13.25]
E        K16157  mmoX; methane monooxygenase component A alpha chain [EC:1.14.13.25]
E        K16158  mmoY; methane monooxygenase component A beta chain [EC:1.14.13.25]
E        K16159  mmoZ; methane monooxygenase component A gamma chain [EC:1.14.13.25]
E        K16160  mmoB; methane monooxygenase regulatory protein B
E        K16161  mmoC; methane monooxygenase component C [EC:1.14.13.25]
E        K16162  mmoD; methane monooxygenase component D
E        K00093  E1.1.1.244; methanol dehydrogenase [EC:1.1.1.244]
E        K14028  mdh1, mxaF; methanol dehydrogenase (cytochrome c) subunit 1 [EC:1.1.2.7]
E        K14029  mdh2, mxaI; methanol dehydrogenase (cytochrome c) subunit 2 [EC:1.1.2.7]
E        K00148  fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
E        K00122  FDH; formate dehydrogenase [EC:1.2.1.2]
E        K00123  E1.2.1.2A; formate dehydrogenase, alpha subunit [EC:1.2.1.2]
E        K00124  E1.2.1.2B1; formate dehydrogenase, beta subunit
E        K00125  E1.2.1.2B2; formate dehydrogenase, beta subunit [EC:1.2.1.2]
E        K00126  E1.2.1.2D, fdsD; formate dehydrogenase, delta subunit [EC:1.2.1.2]
E        K00127  E1.2.1.2G; formate dehydrogenase, gamma subunit
E        K08348  fdnG; formate dehydrogenase-N, alpha subunit [EC:1.2.1.2]
E        K08349  fdnH; formate dehydrogenase-N, beta subunit
E        K08350  fdnI; formate dehydrogenase-N, gamma subunit
D      M00346  Formaldehyde assimilation, serine pathway [PATH:map00680]
E        K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
E        K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
E        K00018  hprA; glycerate dehydrogenase [EC:1.1.1.29]
E        K11529  gk; glycerate 2-kinase [EC:2.7.1.165]
E        K01689  ENO, eno; enolase [EC:4.2.1.11]
E        K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
E        K08692  mtkB; malate-CoA ligase subunit alpha [EC:6.2.1.9]
E        K14067  mtkA; malate-CoA ligase subunit beta [EC:6.2.1.9]
E        K08691  mcl; malyl-CoA lyase [EC:4.1.3.24]
D      M00345  Formaldehyde assimilation, ribulose monophosphate  pathway [PATH:map00680]
E        K08093  hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
E        K13812  fae-hps; bifunctional enzyme Fae/Hps [EC:4.3.-.- 4.1.2.43]
E        K08094  hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
E        K13831  hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
E        K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
E        K16370  pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D      M00344  Formaldehyde assimilation, xylulose monophosphate pathway [PATH:map00680]
E        K00863  E2.7.1.29, DAK1, DAK2; dihydroxyacetone kinase [EC:2.7.1.29]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
E        K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      M00378  F420 biosynthesis [PATH:map00680]
E        K11780  cofG; FO synthase subunit 1 [EC:2.5.1.77]
E        K11781  cofH; FO synthase subunit 2 [EC:2.5.1.77]
E        K14941  cofC; 2-phospho-L-lactate guanylyltransferase [EC:2.7.7.68]
E        K11212  cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
E        K12234  cofE, fbiB; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
E        K14940  cofF; gamma-F420-2:alpha-L-glutamate ligase [EC:6.3.2.32]
D      M00422  Acetyl-CoA pathway, CO2 => acetyl-CoA [PATH:map00680]
E        K00192  cdhA; acetyl-CoA decarbonylase/synthase complex subunit alpha [EC:1.2.7.4]
E        K00195  cdhB; acetyl-CoA decarbonylase/synthase complex subunit epsilon
E        K00193  cdhC; acetyl-CoA decarbonylase/synthase complex subunit beta [EC:2.3.1.-]
E        K00197  cdhE, acsC; acetyl-CoA decarbonylase/synthase complex subunit gamma [EC:2.1.1.245]
E        K00194  cdhD, acsD; acetyl-CoA decarbonylase/synthase complex subunit delta [EC:2.1.1.245]
C    Sulfur metabolism
D      M00176  Sulfur reduction, sulfate => H2S [PATH:map00920]
E        K13811  PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
E        K00958  E2.7.7.4C, met3; sulfate adenylyltransferase [EC:2.7.7.4]
E        K00860  cysC; adenylylsulfate kinase [EC:2.7.1.25]
E        K00955  cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
E        K00957  cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
E        K00956  cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
E        K00390  cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8]
E        K00380  cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
E        K00381  cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]
E        K00392  sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]
B
B  <b>Carbohydrate and lipid metabolism</b>
C    Central carbohydrate metabolism
D      M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:map00010]
E        K00844  HK; hexokinase [EC:2.7.1.1]
E        K12407  GCK; glucokinase [EC:2.7.1.2]
E        K00845  glk; glucokinase [EC:2.7.1.2]
E        K01810  GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]
E        K06859  pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
E        K13810  tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
E        K15916  pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
E        K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
E        K16370  pfkB; 6-phosphofructokinase 2 [EC:2.7.1.11]
E        K01623  ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
E        K01803  TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]
E        K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
E        K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
E        K00927  PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
E        K01834  PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.1]
E        K01689  ENO, eno; enolase [EC:4.2.1.11]
E        K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
E        K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
D      M00002  Glycolysis, core module involving three-carbon compounds [PATH:map00010]
E        K01803  TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]
E        K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
E        K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
E        K00927  PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
E        K01834  PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.1]
E        K15633  gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.1]
E        K15634  gpmB; probable phosphoglycerate mutase [EC:5.4.2.1]
E        K15635  apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.1]
E        K01689  ENO, eno; enolase [EC:4.2.1.11]
E        K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
E        K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
D      M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:map00010 map00020]
E        K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
E        K01610  E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
E        K01689  ENO, eno; enolase [EC:4.2.1.11]
E        K01834  PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.1]
E        K00927  PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
E        K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
E        K01803  TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]
E        K01623  ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
E        K01624  FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
E        K01622  K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
E        K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
E        K02446  glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
E        K11532  glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
E        K04041  fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11]
D      M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:map00010 map00020 map00620]
E        K00163  aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
E        K00161  PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
E        K00162  PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
E        K00627  DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
E        K00382  DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
E        K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
E        K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
E        K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
E        K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
E        K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
D      M00009  Citrate cycle (TCA cycle, Krebs cycle) [PATH:map00020]
E        K01647  CS, gltA; citrate synthase [EC:2.3.3.1]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01682  acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
E        K00031  IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
E        K00030  IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
E        K00164  OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
E        K00658  DLST, sucB; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
E        K00382  DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
E        K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
E        K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
E        K01899  LSC1; succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
E        K01900  LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
E        K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
E        K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
E        K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
E        K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
E        K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
E        K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
D      M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:map00020]
E        K01647  CS, gltA; citrate synthase [EC:2.3.3.1]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01682  acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
E        K00031  IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
E        K00030  IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
D      M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:map00020]
E        K00164  OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
E        K00658  DLST, sucB; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
E        K00382  DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
E        K00174  korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3]
E        K00175  korB; 2-oxoglutarate ferredoxin oxidoreductase subunit beta [EC:1.2.7.3]
E        K00177  korG; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
E        K00176  korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
E        K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
E        K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
E        K01899  LSC1; succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
E        K01900  LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
E        K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
E        K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
E        K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
E        K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
E        K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
E        K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
E        K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
E        K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
E        K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
E        K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
D      M00004  Pentose phosphate pathway (Pentose phosphate cycle) [PATH:map00030]
E        K13937  H6PD; hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]
E        K00036  G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49]
E        K01057  PGLS, pgl, devB; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K07404  pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K00033  E1.1.1.44, PGD, gnd; 6-phosphogluconate dehydrogenase [EC:1.1.1.44]
E        K01783  rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
E        K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
E        K01808  rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
E        K00615  E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]
E        K00616  E2.2.1.2, talA, talB; transaldolase [EC:2.2.1.2]
E        K01810  GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]
E        K06859  pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
E        K13810  tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
E        K15916  pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D      M00006  Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:map00030]
E        K13937  H6PD; hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]
E        K00036  G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49]
E        K01057  PGLS, pgl, devB; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K07404  pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K00033  E1.1.1.44, PGD, gnd; 6-phosphogluconate dehydrogenase [EC:1.1.1.44]
D      M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:map00030]
E        K00615  E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]
E        K00616  E2.2.1.2, talA, talB; transaldolase [EC:2.2.1.2]
E        K13810  tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
E        K01783  rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
E        K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
E        K01808  rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D      M00580  Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:map00030]
E        K08094  hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
E        K08093  hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
E        K13812  fae-hps; bifunctional enzyme Fae/Hps [EC:4.3.-.- 4.1.2.43]
E        K13831  hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
E        K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D      M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:map00030 map00230]
E        K00948  PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D      M00008  Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:map00030]
E        K13937  H6PD; hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]
E        K00036  G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49]
E        K01057  PGLS, pgl, devB; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K07404  pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
E        K01690  edd; phosphogluconate dehydratase [EC:4.2.1.12]
E        K01625  eda; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16]
D      M00308  Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glyceraldehyde-3P + pyruvate [PATH:map00030]
E        K05308  gnaD; gluconate dehydratase [EC:4.2.1.39]
E        K00874  kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
E        K01625  eda; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16]
D      M00309  Non-phosphorylative Entner-Doudoroff pathway, gluconate => glyceraldehyde + pyruvate [PATH:map00030]
E        K05308  gnaD; gluconate dehydratase [EC:4.2.1.39]
E        K11395  kdgA; 2-keto-3-deoxy-gluconate aldolase [EC:4.1.2.-]
C    Other carbohydrate metabolism
D      M00012  Glyoxylate cycle [PATH:map00630]
E        K01647  CS, gltA; citrate synthase [EC:2.3.3.1]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01682  acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
E        K01637  E4.1.3.1, aceA; isocitrate lyase [EC:4.1.3.1]
E        K01638  E2.3.3.9, aceB, glcB; malate synthase [EC:2.3.3.9]
E        K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
E        K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
E        K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
D      M00373  Ethylmalonyl pathway [PATH:map00630]
E        K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
E        K00023  E1.1.1.36, phbB; acetoacetyl-CoA reductase [EC:1.1.1.36]
E        K01715  crt; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
E        K14446  ccr; crotonyl-CoA carboxylase/reductase [EC:1.3.1.85]
E        K05606  MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
E        K14447  ecm; (2R)-ethylmalonyl-CoA mutase
E        K14448  mcd; (2S)-methylsuccinyl-CoA dehydrogenase
E        K14449  K14449, mch; mesaconyl-CoA hydratase
E        K14450  mcl1; L-malyl-CoA/beta-methylmalyl-CoA lyase
E        K01965  PCCA, pccA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
E        K01966  PCCB, pccB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3]
E        K01847  MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
E        K14451  mcl2; (3S)-malyl-CoA thioesterase
D      M00532  Photorespiration [PATH:map00630]
E        K01601  rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
E        K01602  rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
E        K01091  E3.1.3.18, gph; phosphoglycolate phosphatase [EC:3.1.3.18]
E        K11517  HAO; (S)-2-hydroxy-acid oxidase [EC:1.1.3.15]
E        K00104  glcD; glycolate oxidase [EC:1.1.3.15]
E        K11472  glcE; glycolate oxidase FAD binding subunit
E        K11473  glcF; glycolate oxidase iron-sulfur subunit
E        K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
E        K14272  GGAT; glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44 2.6.1.-]
E        K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
E        K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
E        K00018  hprA; glycerate dehydrogenase [EC:1.1.1.29]
E        K15893  HPR1; hydroxypyruvate reductase 1
E        K15919  HPR2; hydroxypyruvate reductase 2
E        K15788  GLYCTK; glycerate kinase [EC:2.7.1.31]
E        K00865  glxK; glycerate kinase [EC:2.7.1.31]
E        K15918  GLYK; D-glycerate 3-kinase [EC:2.7.1.31]
E        K02437  gcvH, GCSH; glycine cleavage system H protein
D      M00013  Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA [PATH:map00640]
E        K00249  ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
E        K01692  paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17]
E        K07511  ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
E        K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
E        K07515  HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
E        K05605  HIBCH; 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
E        K00140  mmsA, iolA, ALDH6A1; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
E        K01578  E4.1.1.9, MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
D      M00014  Glucuronate pathway (uronate pathway) [PATH:map00040]
E        K00012  UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
E        K12447  USP; UDP-sugar pyrophosphorylase [EC:2.7.7.64]
E        K16190  GLCAK; glucuronokinase [EC:2.7.1.43]
E        K13247  CRYL1; L-gulonate 3-dehydrogenase [EC:1.1.1.45]
E        K03331  DCXR; L-xylulose reductase [EC:1.1.1.10]
E        K05351  E1.1.1.9; D-xylulose reductase [EC:1.1.1.9]
E        K00854  xylB, XYLB; xylulokinase [EC:2.7.1.17]
D      M00061  Uronic acid metabolism [PATH:map00040]
E        K01812  uxaC; glucuronate isomerase [EC:5.3.1.12]
E        K00041  uxaB; tagaturonate reductase [EC:1.1.1.58]
E        K01685  uxaA; altronate hydrolase [EC:4.2.1.7]
E        K16849  uxaA1; altronate dehydratase small subunit [EC:4.2.1.7]
E        K16850  uxaA2; altronate dehydratase large subunit [EC:4.2.1.7]
E        K01686  uxuA; mannonate dehydratase [EC:4.2.1.8]
E        K00040  uxuB; fructuronate reductase [EC:1.1.1.57]
D      M00081  Pectin degradation [PATH:map00040]
E        K01051  E3.1.1.11; pectinesterase [EC:3.1.1.11]
E        K01184  E3.2.1.15; polygalacturonase [EC:3.2.1.15]
E        K01213  E3.2.1.67; galacturan 1,4-alpha-galacturonidase [EC:3.2.1.67]
C    Fatty acid metabolism
D      M00082  Fatty acid biosynthesis, initiation [PATH:map00061]
E        K01961  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
E        K01962  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
E        K01963  accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
E        K02160  accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein
E        K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
E        K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
E        K00645  fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
E        K00668  FAS1; fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]
E        K13935  mdcH; malonate decarboxylase epsilon subunit [EC:2.3.1.39]
E        K11533  fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
E        K00648  fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
E        K00667  FAS2; fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86]
E        K00647  fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
E        K09458  fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D      M00083  Fatty acid biosynthesis, elongation [PATH:map00061]
E        K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
E        K00667  FAS2; fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86]
E        K00668  FAS1; fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]
E        K11533  fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
E        K00647  fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
E        K09458  fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
E        K00648  fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
E        K00059  fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
E        K02372  fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
E        K01716  fabA; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
E        K16363  lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
E        K00208  fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
E        K02371  fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.-]
E        K10780  fabL; enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.-]
D      M00085  Fatty acid biosynthesis, elongation, mitochondria [PATH:map00062]
E        K07508  ACAA2; acetyl-CoA acyltransferase 2 [EC:2.3.1.16]
E        K07509  HADHB; acetyl-CoA acyltransferase [EC:2.3.1.16]
E        K00022  HADH; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
E        K07511  ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
E        K07515  HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
E        K07512  MECR, NRBF1; mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38]
D      M00415  Fatty acid biosynthesis, elongation, endoplasmic reticulum [PATH:map00062]
E        K10247  ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
E        K10205  ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
E        K10248  ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
E        K10249  ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
E        K10244  ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
E        K10203  ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
E        K10250  ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
E        K15397  KCS; 3-ketoacyl-CoA synthase [EC:2.3.1.199]
E        K10245  ELO2; fatty acid elongase 2 [EC:2.3.1.199]
E        K10246  ELO3; fatty acid elongase 3 [EC:2.3.1.199]
E        K10251  HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
E        K10703  PHS1, PAS2; very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase [EC:4.2.1.134]
E        K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
D      M00113  Jasmonic acid biosynthesis [PATH:map00592]
E        K00454  LOX2S; lipoxygenase [EC:1.13.11.12]
E        K01723  AOS; hydroperoxide dehydratase [EC:4.2.1.92]
E        K10525  E5.3.99.6, aoc; allene oxide cyclase [EC:5.3.99.6]
E        K05894  E1.3.1.42; 12-oxophytodienoic acid reductase [EC:1.3.1.42]
E        K10526  OPCL1; OPC-8:0 CoA ligase 1 [EC:6.2.1.-]
E        K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
E        K10527  MFP2; enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
E        K00632  E2.3.1.16, fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
E        K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
D      M00086  beta-Oxidation, acyl-CoA synthesis [PATH:map00071]
E        K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
E        K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
D      M00087  beta-Oxidation [PATH:map00071]
E        K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
E        K00249  ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
E        K00255  ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
E        K06445  fadE; acyl-CoA dehydrogenase [EC:1.3.99.-]
E        K09479  ACADVL; very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
E        K01692  paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17]
E        K07511  ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
E        K13767  ysiB, fadB; enoyl-CoA hydratase [EC:4.2.1.17]
E        K00022  HADH; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
E        K07516  fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
E        K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
E        K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
E        K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
E        K07515  HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
E        K10527  MFP2; enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211]
E        K00632  E2.3.1.16, fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
E        K07508  ACAA2; acetyl-CoA acyltransferase 2 [EC:2.3.1.16]
E        K07509  HADHB; acetyl-CoA acyltransferase [EC:2.3.1.16]
E        K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
D      M00088  Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH:map00072]
E        K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
E        K01641  E2.3.3.10; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
E        K01640  E4.1.3.4, HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
E        K00019  E1.1.1.30, bdh; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
E        K01574  E4.1.1.4, adc; acetoacetate decarboxylase [EC:4.1.1.4]
C    Lipid metabolism
D      M00089  Triacylglycerol biosynthesis [PATH:map00561]
E        K00629  GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
E        K13506  GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
E        K13507  GAT; glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase [EC:2.3.1.15 2.3.1.42]
E        K00630  ATS1; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
E        K13508  GPAT; glycerol-3-phosphate acyltransferase [EC:2.3.1.15]
E        K00631  plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
E        K03621  plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]
E        K08591  plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]
E        K00655  plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
E        K13509  LPAAT, AGPAT1, AGPAT2; lysophosphatidate acyltransferase [EC:2.3.1.51]
E        K13513  LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
E        K13517  MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
E        K13519  LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]
E        K13523  AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
E        K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
E        K01080  PPAP2; phosphatidate phosphatase [EC:3.1.3.4]
E        K00635  E2.3.1.20; diacylglycerol O-acyltransferase [EC:2.3.1.20]
E        K11155  DGAT1; diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76]
E        K11160  DGAT2; diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75]
D      M00098  Acylglycerol degradation [PATH:map00561]
E        K01046  E3.1.1.3; triacylglycerol lipase [EC:3.1.1.3]
E        K12298  CEL; bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
E        K16816  PNPLA2, ATGL; patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]
E        K13534  PNPLA3; patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-]
E        K14073  PNLIP, PL; pancreatic triacylglycerol lipase [EC:3.1.1.3]
E        K14074  PNLIPRP1, PLRP1; pancreatic lipase-related protein 1 [EC:3.1.1.3]
E        K14075  PNLIPRP2, PLRP2; pancreatic lipase-related protein 2 [EC:3.1.1.3]
E        K14076  PNLIPRP3, PLRP3; pancreatic lipase-related protein 3 [EC:3.1.1.3]
E        K14452  LIPF; gastric triacylglycerol lipase [EC:3.1.1.3]
E        K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
E        K14675  TGL3; TAG lipase / lysophosphatidylethanolamine acyltransferase [EC:3.1.1.3 2.3.1.-]
E        K01054  MGLL; acylglycerol lipase [EC:3.1.1.23]
D      M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:map00564]
E        K00866  CKI1; choline kinase [EC:2.7.1.32]
E        K14156  CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
E        K00968  PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]
E        K00994  CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
E        K13644  CEPT1; choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2]
D      M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:map00564]
E        K00551  PEMT; phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]
E        K16369  CHO2; phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]
E        K00550  OPI3; methylene-fatty-acyl-phospholipid synthase [EC:2.1.1.16]
E        K00570  pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
D      M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:map00564]
E        K00894  ETNK, EKI; ethanolamine kinase [EC:2.7.1.82]
E        K14156  CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
E        K00967  PCYT2; ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14]
E        K00993  EPT1; ethanolaminephosphotransferase [EC:2.7.8.1]
E        K13644  CEPT1; choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2]
D      M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:map00564]
E        K00981  E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]
E        K00998  pssA, CHO1; phosphatidylserine synthase [EC:2.7.8.8]
E        K01613  psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]
D      M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:map00562]
E        K00888  PI4K; phosphatidylinositol 4-kinase [EC:2.7.1.67]
E        K13711  PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
E        K00889  E2.7.1.68, PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
E        K13712  PIP5KL1; phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68]
E        K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
E        K05857  PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
E        K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
E        K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
E        K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
E        K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
E        K00911  E2.7.1.127, ITPK; 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
D      M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:map00562]
E        K01106  E3.1.3.56; inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56]
E        K01107  INPP1; inositol polyphosphate 1-phosphatase [EC:3.1.3.57]
E        K15422  SAL; 3'(2'), 5'-bisphosphate nucleotidase / inositol polyphosphate 1-phosphatase [EC:3.1.3.7 3.1.3.57]
E        K01109  INPP4; inositol polyphosphate-4-phosphatase [EC:3.1.3.66]
E        K01092  E3.1.3.25, IMPA, suhB; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
E        K15759  IMPAD1, IMPA3; inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7]
E        K10047  VTC4; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase [EC:3.1.3.25 3.1.3.-]
D      M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:map00562]
E        K00913  ITPK1; inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]
E        K00915  IPK2; 1D-myo-Inositol-tetrakisphosphate 5-kinase / inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]
E        K10572  IPPK; inositol-pentakisphosphate 2-kinase [EC:2.7.1.158]
D      M00094  Ceramide biosynthesis [PATH:map00600]
E        K00654  E2.3.1.50; serine palmitoyltransferase [EC:2.3.1.50]
E        K04708  E1.1.1.102; 3-dehydrosphinganine reductase [EC:1.1.1.102]
E        K04709  LAG1; Acyl-CoA-dependent ceramide synthase [EC:2.3.1.24]
E        K04710  CERS; ceramide synthetase [EC:2.3.1.24]
E        K04712  DEGS; sphingolipid delta-4 desaturase [EC:1.14.-.-]
D      M00066  Lactosylceramide biosynthesis [PATH:map00600]
E        K00720  UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
E        K07553  B4GALT6; beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]
D      M00067  Cerebroside and sulfatide biosynthesis [PATH:map00600]
E        K04628  CGT, UGT8; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase [EC:2.4.1.45]
E        K01019  GAL3ST1; galactosylceramide sulfotransferase [EC:2.8.2.11]
D      M00099  Sphingosine biosynthesis [PATH:map00600]
E        K00654  E2.3.1.50; serine palmitoyltransferase [EC:2.3.1.50]
E        K04708  E1.1.1.102; 3-dehydrosphinganine reductase [EC:1.1.1.102]
E        K04709  LAG1; Acyl-CoA-dependent ceramide synthase [EC:2.3.1.24]
E        K04710  CERS; ceramide synthetase [EC:2.3.1.24]
E        K04712  DEGS; sphingolipid delta-4 desaturase [EC:1.14.-.-]
E        K01441  ACER, ASAH3; alkaline ceramidase [EC:3.5.1.23]
E        K12348  ASAH1; acid ceramidase [EC:3.5.1.23]
E        K12349  ASAH2; neutral ceramidase [EC:3.5.1.23]
D      M00100  Sphingosine degradation [PATH:map00600]
E        K04718  E2.7.1.91; sphingosine kinase [EC:2.7.1.91]
E        K01634  E4.1.2.27; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
C    Lipopolysaccharide metabolism
D      M00060  Lipopolysaccharide biosynthesis, KDO2-lipid A [PATH:map00540]
E        K00677  lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
E        K02535  lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
E        K16363  lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]
E        K02536  lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
E        K03269  lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
E        K00748  lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
E        K00912  lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
E        K02527  kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
E        K02517  htrB; lipid A biosynthesis lauroyl acyltransferase [EC:2.3.1.-]
E        K02560  msbB; lipid A biosynthesis (KDO)2-(lauroyl)-lipid iva acyltransferase [EC:2.3.1.-]
D      M00063  CMP-KDO biosynthesis [PATH:map00540]
E        K01627  kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
E        K03270  kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]
E        K00979  kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D      M00064  ADP-L-glycero-D-manno-heptose biosynthesis [PATH:map00540]
E        K03271  gmhA, lpcA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
E        K03272  gmhC, hldE, waaE, rfaE; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]
E        K03273  gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]
E        K03274  gmhD, rfaD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]
D      M00080  Lipopolysaccharide biosynthesis, inner core => outer core => O-antigen [PATH:map00540]
E        K02527  kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
E        K02841  waaC, rfaC; heptosyltransferase I [EC:2.4.-.-]
E        K02843  waaF, rfaF; heptosyltransferase II [EC:2.4.-.-]
E        K02850  waaY, rfaY; heptose (II) phosphotransferase [EC:2.7.1.-]
E        K02848  waaP, rfaP; heptose (I) phosphotransferase [EC:2.7.1.-]
E        K02849  waaQ, rfaQ; heptosyltransferase III [EC:2.4.-.-]
E        K02844  waaG, rfaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]
E        K02840  waaB, rfaB; UDP-D-galactose:(glucosyl)LPS alpha-1,6-D-galactosyltransferase [EC:2.4.1.-]
E        K03278  waaI, rfaI; UDP-D-galactose:(glucosyl)LPS alpha-1,3-D-galactosyltransferase [EC:2.4.1.44]
E        K03279  waaJ, rfaJ; UDP-glucose:(galactosyl)LPS alpha-1,2-glucosyltransferase [EC:2.4.1.58]
E        K03280  waaK, rfaK; UDP-N-acetylglucosamine:(glucosyl)LPS alpha-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.56]
E        K02847  waaL, rfaL; O-antigen ligase [EC:6.-.-.-]
C    Sugar metabolism
D      M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:map00520]
E        K00844  HK; hexokinase [EC:2.7.1.1]
E        K00845  glk; glucokinase [EC:2.7.1.2]
E        K12407  GCK; glucokinase [EC:2.7.1.2]
E        K00886  ppgK; polyphosphate glucokinase [EC:2.7.1.63]
E        K01835  pgm; phosphoglucomutase [EC:5.4.2.2]
E        K00963  UGP2, galU, galF; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
E        K00965  galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D      M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:map00520 map00052]
E        K00849  galK; galactokinase [EC:2.7.1.6]
E        K00965  galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
D      M00565  Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:map00500]
E        K00975  glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]
E        K00703  E2.4.1.21, glgA; starch synthase [EC:2.4.1.21]
E        K16148  glgA; starch synthase [EC:2.4.1.21]
E        K00700  glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
E        K16149  K16149; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
E        K00688  E2.4.1.1, glgP, PYG; starch phosphorylase [EC:2.4.1.1]
E        K16153  K16153; phosphorylase / glycogen(starch) synthase [EC:2.4.1.1 2.4.1.11]
E        K02438  treX, glgX; glycogen operon protein [EC:3.2.1.-]
E        K06044  treY, glgY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15]
E        K01236  treZ, glgZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]
C    Glycan metabolism
D      M00055  N-glycan precursor biosynthesis [PATH:map00510]
E        K01001  ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]
E        K07432  ALG13; beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]
E        K07441  ALG14; beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]
E        K03842  ALG1; beta-1,4-mannosyltransferase [EC:2.4.1.142]
E        K03843  ALG2; alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]
E        K03844  ALG11; alpha-1,2-mannosyltransferase [EC:2.4.1.131]
E        K03845  ALG3; alpha-1,3-mannosyltransferase [EC:2.4.1.258]
E        K03846  ALG9; alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]
E        K03847  ALG12; alpha-1,6-mannosyltransferase [EC:2.4.1.260]
E        K00729  ALG5; dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117]
E        K03848  ALG6; alpha-1,3-glucosyltransferase [EC:2.4.1.267]
E        K03849  ALG8; alpha-1,3-glucosyltransferase [EC:2.4.1.265]
E        K03850  ALG10; alpha-1,2-glucosyltransferase [EC:2.4.1.256]
D      M00073  N-glycan precursor trimming [PATH:map00510]
E        K01228  GCS1; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]
E        K05546  GANAB; alpha 1,3-glucosidase [EC:3.2.1.84]
E        K01230  MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D      M00074  N-glycan biosynthesis, high-mannose type [PATH:map00510 map00513]
E        K05546  GANAB; alpha 1,3-glucosidase [EC:3.2.1.84]
E        K01230  MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
E        K05528  OCH1; alpha 1,6-mannosyltransferase [EC:2.4.1.232]
E        K05529  MNN9; mannan polymerase complexes MNN9 subunit [EC:2.4.1.-]
E        K05530  VAN1; mannan polymerase I complex VAN1 subunit [EC:2.4.1.-]
E        K05531  MNN10; mannan polymerase II complex MNN10 subunit [EC:2.4.1.-]
E        K05532  MNN11; mannan polymerase II complex MNN11 subunit [EC:2.4.1.-]
E        K05533  ANP1; mannan polymerase II complex ANP1 subunit [EC:2.4.1.-]
E        K05534  HOC1; mannan polymerase II complex HOC1 subunit [EC:2.4.1.-]
E        K05535  MNN2; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
D      M00075  N-glycan biosynthesis, complex type [PATH:map00510]
E        K01231  MAN2; alpha-mannosidase II [EC:3.2.1.114]
E        K00736  MGAT2; alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143]
E        K00737  MGAT3; beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.144]
E        K00738  MGAT4A_B; alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]
E        K00744  MGAT5; alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]
E        K09661  MGAT5B; mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-]
E        K13748  MGAT4C; alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C [EC:2.4.1.201 2.4.1.145]
E        K00717  FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
E        K07966  B4GALT1; beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
E        K07967  B4GALT2; beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
E        K07968  B4GALT3; beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-]
E        K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1]
E        K00779  SIAT2, ST6GAL2; beta-galactoside alpha2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.99.1]
D      M00056  O-glycan biosynthesis, mucin type core [PATH:map00512]
E        K00710  GALNT; polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]
E        K00731  C1GALT1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122]
E        K09653  C1GALT2, C1GALT1C1; C1GALT1-specific chaperone 1 [EC:2.4.1.-]
E        K00727  GCNT1; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102]
E        K09662  GCNT3; N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-]
E        K09663  GCNT4; beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-]
E        K00739  B3GNT6; acetylgalactosaminyl-0-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147]
D      M00070  Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:map00601]
E        K03766  B3GNT5; beta-1,3-N-acetylglucosaminyltransferase 5 [EC:2.4.1.206]
E        K07819  B3GALT1; beta-1,3-galactosyltransferase 1 [EC:2.4.1.-]
E        K07820  B3GALT2; beta-1,3-galactosyltransferase 2 [EC:2.4.1.-]
E        K03877  B3GALT5; beta-1,3-galactosyltransferase 5 [EC:2.4.1.-]
D      M00071  Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:map00601]
E        K03766  B3GNT5; beta-1,3-N-acetylglucosaminyltransferase 5 [EC:2.4.1.206]
E        K07966  B4GALT1; beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
E        K07967  B4GALT2; beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
E        K07968  B4GALT3; beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-]
E        K07969  B4GALT4; beta-1,4-galactosyltransferase 4 [EC:2.4.1.90 2.4.1.-]
D      M00068  Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:map00603]
E        K01988  A4GALT; lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]
E        K00719  B3GALNT1, B3GALT3; galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79]
D      M00069  Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:map00604]
E        K03370  SIAT9; lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.99.9]
E        K03371  SIAT8A; alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8]
E        K03369  SIAT8E; alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8E) [EC:2.4.99.-]
D      M00065  GPI-anchor biosynthesis, core oligosaccharide [PATH:map00563]
E        K03857  PIGA, GPI3; phosphatidylinositol glycan, class A [EC:2.4.1.198]
E        K03434  PIGL; N-acetylglucosaminylphosphatidylinositol deacetylase [EC:3.5.1.89]
E        K05283  PIGW; phosphatidylinositol glycan, class W [EC:2.3.-.-]
E        K05284  PIGM; phosphatidylinositol glycan, class M [EC:2.4.1.-]
E        K05285  PIGN; phosphatidylinositol glycan, class N [EC:2.7.-.-]
E        K07542  PIGV; phosphatidylinositol glycan, class V [EC:2.4.1.-]
E        K05286  PIGB; phosphatidylinositol glycan, class B [EC:2.4.1.-]
E        K05287  PIGF; phosphatidylinositol glycan, class F [EC:2.7.-.-]
C    Glycosaminoglycan metabolism
D      M00057  Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:map00532]
E        K00771  XYLT; protein xylosyltransferase [EC:2.4.2.26]
E        K00733  B4GALT7; xylosylprotein 4-beta-galactosyltransferase [EC:2.4.1.133]
E        K00734  B3GALT6; galactosylxylosylprotein 3-beta-galactosyltransferase [EC:2.4.1.134]
E        K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]
D      M00058  Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:map00532]
E        K00746  CSGALNACT1_2; chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175]
E        K13499  CHSY; chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226]
E        K00747  CHPF; chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226]
E        K03419  CHPF2; chondroitin polymerizing factor 2 [EC:2.4.1.226]
D      M00059  Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:map00534]
E        K02369  EXTL2; alpha-1,4-N-acetylglucosaminyltransferase EXTL2 [EC:2.4.1.223]
E        K02370  EXTL3; alpha-1,4-N-acetylglucosaminyltransferase EXTL3 [EC:2.4.1.223 2.4.1.224]
E        K02366  EXT1; glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225]
E        K02367  EXT2; glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225]
E        K02368  EXTL1; alpha-1,4-N-acetylglucosaminyltransferase EXTL1 [EC:2.4.1.224]
E        K02576  NDST1; heparan sulfate N-deacetylase/N-sulfotransferase NDST1 [EC:3.1.1.- 2.8.2.-]
E        K02577  NDST2; heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-]
E        K02578  NDST3; heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.1.1.- 2.8.2.-]
E        K02579  NDST4; heparan sulfate N-deacetylase/N-sulfotransferase NDST4 [EC:3.1.1.- 2.8.2.-]
E        K01793  GLCE; heparosan-N-sulfate-glucuronate 5-epimerase [EC:5.1.3.17]
D      M00076  Dermatan sulfate degradation [PATH:map00531]
E        K01136  IDS; iduronate 2-sulfatase [EC:3.1.6.13]
E        K01217  IDUA; L-iduronidase [EC:3.2.1.76]
E        K01135  ARSB; arylsulfatase B [EC:3.1.6.12]
E        K01197  hya; hyaluronoglucosaminidase [EC:3.2.1.35]
E        K01195  E3.2.1.31, GUSB, uidA; beta-glucuronidase [EC:3.2.1.31]
D      M00077  Chondroitin sulfate degradation [PATH:map00531]
E        K01135  ARSB; arylsulfatase B [EC:3.1.6.12]
E        K01197  hya; hyaluronoglucosaminidase [EC:3.2.1.35]
E        K01195  E3.2.1.31, GUSB, uidA; beta-glucuronidase [EC:3.2.1.31]
E        K01132  GALNS; N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]
D      M00078  Heparan sulfate degradation [PATH:map00531]
E        K07964  HPSE; heparanase 1 [EC:3.2.1.166]
E        K07965  HPSE2; heparanase 2 [EC:3.2.1.-]
E        K01136  IDS; iduronate 2-sulfatase [EC:3.1.6.13]
E        K01217  IDUA; L-iduronidase [EC:3.2.1.76]
E        K01565  SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
E        K10532  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78]
E        K01205  NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50]
E        K01195  E3.2.1.31, GUSB, uidA; beta-glucuronidase [EC:3.2.1.31]
E        K01137  GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]
D      M00079  Keratan sulfate degradation [PATH:map00531]
E        K01132  GALNS; N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]
E        K12309  GLB1, ELNR1; beta-galactosidase [EC:3.2.1.23]
E        K01137  GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]
E        K12373  HEXA_B; hexosaminidase [EC:3.2.1.52]
C    Terpenoid backbone biosynthesis
D      M00095  C5 isoprenoid biosynthesis, mevalonate pathway [PATH:map00900]
E        K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
E        K01641  E2.3.3.10; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
E        K00021  E1.1.1.34; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
E        K00869  E2.7.1.36, MVK, mvaK1; mevalonate kinase [EC:2.7.1.36]
E        K00938  E2.7.4.2, mvaK2; phosphomevalonate kinase [EC:2.7.4.2]
E        K13273  PMVK; phosphomevalonate kinase [EC:2.7.4.2]
E        K01597  MVD, mvaD; diphosphomevalonate decarboxylase [EC:4.1.1.33]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
D      M00096  C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:map00900]
E        K01662  dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
E        K00099  dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
E        K00991  ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
E        K12506  ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]
E        K00919  ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
E        K01770  ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
E        K03526  E1.17.7.1, gcpE, ispG; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1]
E        K03527  E1.17.1.2, lytB, ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [EC:1.17.1.2]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
D      M00364  C10-C20 isoprenoid biosynthesis, bacteria [PATH:map00900]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
E        K00795  ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
E        K13789  GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
E        K13787  idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      M00365  C10-C20 isoprenoid biosynthesis, archaea [PATH:map00900]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
E        K13787  idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      M00366  C10-C20 isoprenoid biosynthesis, plants [PATH:map00900]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
E        K14066  GPS; geranyl diphosphate synthase [EC:2.5.1.1]
E        K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
E        K13789  GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      M00367  C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:map00900]
E        K01823  idi, IDI; isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2]
E        K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
E        K00804  GGPS1; geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29]
C    Sterol biosynthesis
D      M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH:map00100]
E        K01852  E5.4.99.7, LSS, ERG7; lanosterol synthase [EC:5.4.99.7]
E        K05917  CYP51; cytochrome P450, family 51 (sterol 14-demethylase) [EC:1.14.13.70]
E        K00222  E1.3.1.70, TM7SF2, ERG24; delta14-sterol reductase [EC:1.3.1.70]
E        K07750  E1.14.13.72, SC4MOL, ERG25; methylsterol monooxygenase [EC:1.14.13.72]
E        K07748  E1.1.1.170, NSDHL, ERG26; sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170]
E        K09827  ERG27; 3-keto steroid reductase [EC:1.1.1.270]
E        K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
E        K09828  DHCR24; delta24-sterol reductase [EC:1.3.1.72]
E        K01824  EBP; cholestenol delta-isomerase [EC:5.3.3.5]
E        K00227  SC5DL, ERG3; lathosterol oxidase [EC:1.14.21.6]
E        K00213  DHCR7; 7-dehydrocholesterol reductase [EC:1.3.1.21]
D      M00102  Ergocalciferol biosynthesis [PATH:map00100]
E        K00559  E2.1.1.41, SMT1, ERG6; sterol 24-C-methyltransferase [EC:2.1.1.41]
E        K09829  ERG2; C-8 sterol isomerase [EC:5.-.-.-]
E        K00227  SC5DL, ERG3; lathosterol oxidase [EC:1.14.21.6]
E        K09831  ERG5; C-22 sterol desaturase [EC:1.14.14.-]
E        K00223  ERG4; delta24(24(1))-sterol reductase [EC:1.3.1.71]
D      M00103  Cholecalciferol biosynthesis [PATH:map00100]
E        K07419  CYP2R1; cytochrome P450, family 2, subfamily R, polypeptide 1 (vitamin D 25-hydroxylase) [EC:1.14.13.159]
E        K07438  CYP27B; cytochrome P450, family 27, subfamily B (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.13.13]
D      M00104  Bile acid biosynthesis, cholesterol => cholate [PATH:map00120]
E        K00489  CYP7A1; cytochrome P450, family 7, subfamily A (cholesterol 7alpha-monooxygenase) [EC:1.14.13.17]
E        K12408  HSD3B7; cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181]
E        K07431  CYP8B; cytochrome P450, family 8, subfamily B (sterol 12-alpha-hydroxylase) [EC:1.14.13.95]
E        K00251  AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
E        K00037  E1.1.1.50; 3-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.50]
E        K00488  CYP27A; cytochrome P450, family 27, subfamily A (cholestanetriol 26-monooxygenase) [EC:1.14.13.15]
E        K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
E        K01796  E5.1.99.4, AMACR, mcr; alpha-methylacyl-CoA racemase [EC:5.1.99.4]
E        K10214  ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
E        K12405  HSD17B4; 3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase [EC:1.1.1.35 4.2.1.107]
E        K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
E        K11992  ACOT8, PTE; acyl-CoA thioesterase 8 [EC:3.1.2.27]
D      M00106  Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH:map00120]
E        K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
E        K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
D      M00107  Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone [PATH:map00140]
E        K00498  CYP11A; cytochrome P450, family 11, subfamily A (cholesterol monooxygenase (side-chain-cleaving)) [EC:1.14.15.6]
E        K00070  HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
E        K01822  E5.3.3.1; steroid delta-isomerase [EC:5.3.3.1]
D      M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone [PATH:map00140]
E        K00513  CYP21; cytochrome P450, family 21, subfamily A (steroid 21-monooxygenase) [EC:1.14.99.10]
E        K00497  CYP11B1; cytochrome P450, family 11, subfamily B1 (steroid 11beta-monooxygenase) [EC:1.14.15.4]
E        K07433  CYP11B2; cytochrome P450, family 11, subfamily B2 (steroid 11beta-monooxygenase / corticosterone 18-monooxygenase) [EC:1.14.15.4 1.14.15.5]
D      M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:map00140]
E        K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase) [EC:1.14.99.9]
E        K00513  CYP21; cytochrome P450, family 21, subfamily A (steroid 21-monooxygenase) [EC:1.14.99.10]
E        K00497  CYP11B1; cytochrome P450, family 11, subfamily B1 (steroid 11beta-monooxygenase) [EC:1.14.15.4]
E        K07433  CYP11B2; cytochrome P450, family 11, subfamily B2 (steroid 11beta-monooxygenase / corticosterone 18-monooxygenase) [EC:1.14.15.4 1.14.15.5]
E        K15680  HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
E        K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
D      M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:map00140]
E        K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase) [EC:1.14.99.9]
E        K00070  HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
E        K01822  E5.3.3.1; steroid delta-isomerase [EC:5.3.3.1]
E        K07434  CYP19A; cytochrome P450, family 19, subfamily A [EC:1.14.14.1]
C    Other terpenoid biosynthesis
D      M00097  beta-Carotene biosynthesis, GGAP => beta-carotene [PATH:map00906]
E        K02291  crtB; phytoene synthase [EC:2.5.1.32]
E        K02293  PDS, crtP; 15-cis-phytoene desaturase [EC:1.3.5.5]
E        K15744  Z-ISO; zeta-carotene isomerase [EC:5.2.1.12]
E        K00514  ZDS, crtQ; zeta-carotene desaturase [EC:1.3.5.6]
E        K09835  crtISO, crtH; prolycopene isomerase [EC:5.2.1.13]
E        K06443  lcyB, crtL1, crtY; lycopene beta-cyclase [EC:5.5.1.19]
D      M00372  Abscisic acid biosynthesis, beta-carotene => abscisic acid [PATH:map00906]
E        K15746  crtZ; beta-carotene 3-hydroxylase [EC:1.14.13.129]
E        K15747  LUT5, CYP97A3; cytochrome P450, family 97, subfamily A (beta-ring hydroxylase) [EC:1.14.-.-]
E        K09838  ZEP, ABA1; zeaxanthin epoxidase [EC:1.14.13.90]
E        K14594  NSY; neoxanthin synthase [EC:5.3.99.9]
E        K09840  NCED; 9-cis-epoxycarotenoid dioxygenase [EC:1.13.11.51]
E        K09841  ABA2; xanthoxin dehydrogenase [EC:1.1.1.288]
E        K09842  AAO3; abscisic-aldehyde oxidase [EC:1.2.3.14]
D      M00371  Castasterone biosynthesis, campesterol => castasterone [PATH:map00905]
E        K09587  CYP90B1, DWF4; cytochrome P450, family 90, subfamily B, polypeptide 1 (steroid 22-alpha-hydroxylase) [EC:1.14.13.-]
E        K12639  CYP724B1, D11; cytochrome P450, family 724, subfamily B, polypeptide 1 [EC:1.14.13.-]
E        K09588  CYP90A1, CPD; cytochrome P450, family 90, subfamily A, polypeptide 1 [EC:1.14.-.-]
E        K09591  DET2; steroid 5-alpha-reductase [EC:1.3.1.22]
E        K12637  CYP90C1, ROT3; cytochrome P450, family 90, subfamily C, polypeptide 1 (3-epi-6-deoxocathasterone 23-monooxygenase) [EC:1.14.13.112]
E        K12638  CYP90D1; cytochrome P450, family 90, subfamily D, polypeptide 1 (3-epi-6-deoxocathasterone 23-monooxygenase) [EC:1.14.13.112]
E        K09590  CYP85A1, BR6OX1; cytochrome P450, family 85, subfamily A, polypeptide 1 (brassinosteroid-6-oxidase 1) [EC:1.14.-.-]
E        K12640  CYP85A2, BR6OX2; cytochrome P450, family 85, subfamily A, polypeptide 2 (brassinosteroid-6-oxidase 2) [EC:1.14.-.-]
B
B  <b>Nucleotide and amino acid metabolism</b>
C    Purine metabolism
D      M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:map00230]
E        K00764  purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
E        K01945  purD; phosphoribosylamine--glycine ligase [EC:6.3.4.13]
E        K11787  GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
E        K11788  ADE5; phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
E        K13713  purCD; fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
E        K00601  E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
E        K11175  purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
E        K08289  purT; phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2]
E        K01952  purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
E        K01933  purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
E        K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
E        K11808  ADE2; phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21]
E        K01589  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
E        K01588  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
E        K01923  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
E        K01756  purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]
E        K00602  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
E        K01492  E2.1.2.3; phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.3]
E        K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.-]
E        K11176  purO; IMP cyclohydrolase [EC:3.5.4.10]
D      M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:map00230]
E        K01939  E6.3.4.4, purA; adenylosuccinate synthase [EC:6.3.4.4]
E        K01756  purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]
E        K00939  E2.7.4.3, adk; adenylate kinase [EC:2.7.4.3]
E        K00940  E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
E        K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
E        K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
D      M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:map00230]
E        K00088  E1.1.1.205, guaB; IMP dehydrogenase [EC:1.1.1.205]
E        K01951  E6.3.5.2, guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
E        K00942  E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]
E        K00940  E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
E        K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
E        K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
D      M00546  Purine degradation, xanthine => urea [PATH:map00230]
E        K00106  XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
E        K00087  ygeS, xdhA; xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4]
E        K13479  ygeT, xdhB; xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4]
E        K13480  ygeU, xdhC; xanthine dehydrogenase iron-sulfur-binding subunit
E        K13481  xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]
E        K13482  xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]
E        K11177  yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
E        K11178  yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
E        K13483  yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
E        K00365  E1.7.3.3; urate oxidase [EC:1.7.3.3]
E        K16838  pucL; urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:1.7.3.3 4.1.1.-]
E        K16839  hpxO; FAD-dependent urate hydroxylase [EC:1.14.13.113]
E        K13484  TTHL; 5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.-]
E        K07127  uraH, pucM, hiuH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]
E        K13485  PRHOXNB, URAD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.-]
E        K16840  hpxQ; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.-]
E        K01466  allB; allantoinase [EC:3.5.2.5]
E        K16842  hpxB; allantoinase [EC:3.5.2.5]
E        K01477  alc, ALLC; allantoicase [EC:3.5.3.4]
C    Pyrimidine metabolism
D      M00051  Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:map00240]
E        K11540  CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
E        K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
E        K01465  URA4, pyrC; dihydroorotase [EC:3.5.2.3]
E        K01954  K01954; carbamoyl-phosphate synthase [EC:6.3.5.5]
E        K01955  carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
E        K01956  carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
E        K00609  pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
E        K00610  pyrI; aspartate carbamoyltransferase regulatory subunit
E        K00608  pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2]
E        K00226  pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
E        K00254  DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
E        K13421  UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
E        K00762  pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
E        K01591  pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D      M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:map00240]
E        K13800  CMPK1, UMPK; UMP-CMP kinase [EC:2.7.4.- 2.7.4.14]
E        K13809  CMPK2; UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]
E        K00945  cmk; cytidylate kinase [EC:2.7.4.14]
E        K13799  panC-cmk; pantoate ligase / cytidylate kinase [EC:6.3.2.1 2.7.4.14]
E        K00940  E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
E        K01937  E6.3.4.2, pyrG; CTP synthase [EC:6.3.4.2]
D      M00053  Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH:map00240]
E        K00524  nrdJ; ribonucleotide reductase, class II [EC:1.17.4.1]
E        K00525  E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
E        K00526  E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
E        K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
E        K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
E        K00940  E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
E        K00527  nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2]
E        K01494  E3.5.4.13, dcd; dCTP deaminase [EC:3.5.4.13]
E        K01520  dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]
E        K00560  thyA, TYMS; thymidylate synthase [EC:2.1.1.45]
E        K13998  DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
E        K00943  E2.7.4.9, tmk; dTMP kinase [EC:2.7.4.9]
D      M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:map00240]
E        K00207  E1.3.1.2, DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
E        K01464  E3.5.2.2, DPYS; dihydropyrimidinase [EC:3.5.2.2]
E        K01431  E3.5.1.6; beta-ureidopropionase [EC:3.5.1.6]
C    Serine and threonine metabolism
D      M00020  Serine biosynthesis, glycerate-3P => serine [PATH:map00260]
E        K00058  serA, PHGDH; D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]
E        K00831  serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]
E        K01079  serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]
D      M00018  Threonine biosynthesis, apartate => homoserine => threonine [PATH:map00260]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K12524  thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
E        K12525  metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
E        K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K00003  E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]
E        K00872  thrB1; homoserine kinase [EC:2.7.1.39]
E        K02204  thrB2; homoserine kinase type II [EC:2.7.1.39]
E        K02203  thrH; phosphoserine / homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]
E        K01733  thrC; threonine synthase [EC:4.2.3.1]
D      M00555  Betaine biosynthesis, choline => betaine [PATH:map00260]
E        K00108  E1.1.99.1, betA, CHDH; choline dehydrogenase [EC:1.1.99.1]
E        K11440  gbsB; choline dehydrogenase [EC:1.1.1.1]
E        K00130  betB, gbsA; betaine-aldehyde dehydrogenase [EC:1.2.1.8]
C    Cysteine and methionine metabolism
D      M00021  Cysteine biosynthesis, serine => cysteine [PATH:map00270]
E        K00640  cysE; serine O-acetyltransferase [EC:2.3.1.30]
E        K01738  cysK; cysteine synthase A [EC:2.5.1.47]
E        K12339  cysM; cysteine synthase B [EC:2.5.1.47]
E        K13034  ATCYSC1; L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9]
E        K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / spermine synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D      M00338  Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:map00270]
E        K01697  E4.2.1.22, CBS; cystathionine beta-synthase [EC:4.2.1.22]
E        K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / spermine synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
E        K01758  E4.4.1.1; cystathionine gamma-lyase [EC:4.4.1.1]
D      M00017  Methionine biosynthesis, apartate => homoserine => methionine [PATH:map00270]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K12524  thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
E        K12525  metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
E        K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K00003  E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]
E        K00651  metA; homoserine O-succinyltransferase [EC:2.3.1.46]
E        K01739  metB; cystathionine gamma-synthase [EC:2.5.1.48]
E        K01760  metC; cystathionine beta-lyase [EC:4.4.1.8]
E        K00548  metH, MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
E        K00549  metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      M00034  Methionine salvage pathway [PATH:map00270]
E        K00789  metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
E        K01611  speD, AMD1; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
E        K00797  speE, SRM; spermidine synthase [EC:2.5.1.16]
E        K01243  mtnN, mtn, pfs; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase [EC:3.2.2.9]
E        K01244  MTN; 5'-methylthioadenosine nucleosidase [EC:3.2.2.16]
E        K00899  mtnK; 5-methylthioribose kinase [EC:2.7.1.100]
E        K00772  E2.4.2.28, mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
E        K08963  mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
E        K16054  DEP1; methylthioribulose 1-phosphate dehydratase / enolase-phosphatase E1 [EC:4.2.1.109 3.1.3.77]
E        K08964  mtnB; methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109]
E        K09880  mtnC, ENOPH1; enolase-phosphatase E1 [EC:3.1.3.77]
E        K08965  mtnW; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [EC:5.3.2.5]
E        K08966  mtnX; 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [EC:3.1.3.87]
E        K08967  mtnD, mtnZ, ADI1; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54]
E        K00815  TAT; tyrosine aminotransferase [EC:2.6.1.5]
E        K08969  mtnE, mtnV; aminotransferase [EC:2.6.1.-]
E        K00832  tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
E        K00838  ARO8; aromatic amino acid aminotransferase I [EC:2.6.1.57 2.6.1.27 2.6.1.5]
D      M00035  Methionine degradation [PATH:map00270]
E        K00789  metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
E        K00558  E2.1.1.37, DNMT, dcm; DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37]
E        K01251  E3.3.1.1, ahcY; adenosylhomocysteinase [EC:3.3.1.1]
E        K01697  E4.2.1.22, CBS; cystathionine beta-synthase [EC:4.2.1.22]
E        K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / spermine synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
D      M00368  Ethylene biosynthesis, methionine => ethylene [PATH:map00270]
E        K00789  metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
E        K01762  ACS; 1-aminocyclopropane-1-carboxylate synthase [EC:4.4.1.14]
E        K05933  E1.14.17.4; aminocyclopropanecarboxylate oxidase [EC:1.14.17.4]
C    Branched-chain amino acid metabolism
D      M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:map00290]
E        K01652  E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
E        K01653  E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]
E        K11258  ilvM; acetolactate synthase II small subunit [EC:2.2.1.6]
E        K00053  ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
E        K01687  ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
E        K00826  E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:map00290]
E        K09011  cimA; D-citramalate synthase [EC:2.3.1.182]
E        K01703  leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
E        K01704  leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
E        K00052  leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D      M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:map00290]
E        K01754  E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19]
E        K01652  E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
E        K01653  E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]
E        K11258  ilvM; acetolactate synthase II small subunit [EC:2.2.1.6]
E        K00053  ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
E        K01687  ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
E        K00826  E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:map00290]
E        K01649  leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
E        K01702  LEU1; 3-isopropylmalate dehydratase [EC:4.2.1.33]
E        K01703  leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
E        K01704  leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
E        K00052  leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D      M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:map00280]
E        K00826  E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]
E        K00166  E1.2.4.4A, bkdA1; 2-oxoisovalerate dehydrogenase E1 component, alpha subunit [EC:1.2.4.4]
E        K00167  E1.2.4.4B, bkdA2; 2-oxoisovalerate dehydrogenase E1 component, beta subunit [EC:1.2.4.4]
E        K11381  E1.2.4.4C, bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
E        K09699  E2.3.1.168, bkdB; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
E        K00382  DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
E        K00253  IVD, ivd; isovaleryl-CoA dehydrogenase [EC:1.3.8.4]
E        K00249  ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
E        K01968  E6.4.1.4A; 3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4]
E        K01969  E6.4.1.4B; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]
E        K05607  AUH; methylglutaconyl-CoA hydratase [EC:4.2.1.18]
E        K13766  liuC; methylglutaconyl-CoA hydratase [EC:4.2.1.18]
E        K01640  E4.1.3.4, HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
C    Lysine metabolism
D      M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:map00300]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K12524  thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
E        K12525  metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
E        K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K01714  dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
E        K00215  dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
E        K00674  dapD; 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [EC:2.3.1.117]
E        K00821  argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
E        K14267  dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]
E        K01439  dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
E        K01778  dapF; diaminopimelate epimerase [EC:5.1.1.7]
E        K01586  lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      M00525  Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:map00300]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K01714  dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
E        K00215  dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
E        K05822  E2.3.1.89; tetrahydrodipicolinate N-acetyltransferase [EC:2.3.1.89]
E        K00841  patA; aminotransferase [EC:2.6.1.-]
E        K05823  E3.5.1.47; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]
E        K01778  dapF; diaminopimelate epimerase [EC:5.1.1.7]
E        K01586  lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      M00526  Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:map00300]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K12524  thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
E        K12525  metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
E        K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K01714  dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
E        K00215  dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
E        K03340  E1.4.1.16; diaminopimelate dehydrogenase [EC:1.4.1.16]
E        K01586  lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:map00300]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K12524  thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
E        K12525  metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
E        K12526  lysAC; bifunctional diaminopimelate decarboxylase / aspartate kinase [EC:4.1.1.20 2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K01714  dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
E        K00215  dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
E        K10206  E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
E        K01778  dapF; diaminopimelate epimerase [EC:5.1.1.7]
E        K01586  lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      M00030  Lysine biosynthesis, 2-oxoglutarate => 2-aminoadipate => lysine [PATH:map00300]
E        K01655  E2.3.3.14; homocitrate synthase [EC:2.3.3.14]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01705  LYS4; homoaconitate hydratase [EC:4.2.1.36]
E        K05824  E1.1.1.87; homoisocitrate dehydrogenase [EC:1.1.1.87]
E        K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
E        K00838  ARO8; aromatic amino acid aminotransferase I [EC:2.6.1.57 2.6.1.27 2.6.1.5]
E        K00143  LYS2; L-aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31]
E        K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
E        K00293  E1.5.1.10; saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]
E        K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]
D      M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH:map00300]
E        K01655  E2.3.3.14; homocitrate synthase [EC:2.3.3.14]
E        K02594  nifV; homocitrate synthase NifV [EC:2.3.3.14]
E        K10977  aksA; methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
E        K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
E        K01705  LYS4; homoaconitate hydratase [EC:4.2.1.36]
E        K16792  lysT, aksD; homoaconitate hydratase / methanogen homoaconitase large subunit [EC:4.2.1.36 4.2.1.114]
E        K16793  lysU, aksE; homoaconitate hydratase / methanogen homoaconitase small subunit [EC:4.2.1.36 4.2.1.114]
E        K05824  E1.1.1.87; homoisocitrate dehydrogenase [EC:1.1.1.87]
E        K10978  aksF; threo-isocitrate dehydrogenase [EC:1.1.1.-]
D      M00031  Lysine biosynthesis, 2-aminoadipate => lysine [PATH:map00300]
E        K05827  lysX; alpha-aminoadipate--LysW ligase LysX [EC:6.3.2.-]
E        K05828  lysZ; acetylglutamate/LysW-gamma-L-alpha-aminoadipate kinase [EC:2.7.2.8 2.7.2.-]
E        K05829  lysY; N-acetyl-gamma-glutamyl-phosphate/LysW-gamma-L-alpha-aminoadipyl-6-phosphate reductase [EC:1.2.1.38 1.2.1.-]
E        K05830  lysJ; acetylornithine/LysW-gamma-L-lysine aminotransferase [EC:2.6.1.11 2.6.1.-]
E        K05831  argE1, lysK; LysW-gamma-L-lysine carboxypeptidase
D      M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:map00310]
E        K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]
E        K00291  E1.5.1.8; saccharopine dehydrogenase (NADP+, L-lysine forming) [EC:1.5.1.8]
E        K00292  E1.5.1.9; saccharopine dehydrogenase (NAD+, L-glutamate forming) [EC:1.5.1.9]
E        K00293  E1.5.1.10; saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]
E        K14157  AASS; alpha-aminoadipic semialdehyde synthase [EC:1.5.1.8 1.5.1.9]
E        K00143  LYS2; L-aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31]
E        K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
E        K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
E        K00164  OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
E        K00658  DLST, sucB; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
E        K00252  GCDH, gcdH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
E        K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
E        K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
E        K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
E        K01692  paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17]
E        K07515  HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
E        K07511  ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
E        K00022  HADH; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
C    Arginine and proline metabolism
D      M00015  Proline biosynthesis, glutamate => proline [PATH:map00330]
E        K00931  proB; glutamate 5-kinase [EC:2.7.2.11]
E        K00147  proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
E        K12657  ALDH18A1, P5CS; delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41]
E        K00286  E1.5.1.2, proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D      M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:map00330]
E        K00619  argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
E        K00620  argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
E        K00618  E2.3.1.1; amino-acid N-acetyltransferase [EC:2.3.1.1]
E        K11067  NAGS; N-acetylglutamate synthase [EC:2.3.1.1]
E        K14681  argHA; argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1]
E        K14682  argAB; amino-acid N-acetyltransferase [EC:2.3.1.1]
E        K00930  argB; acetylglutamate kinase [EC:2.7.2.8]
E        K00145  argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
E        K05828  lysZ; acetylglutamate/LysW-gamma-L-alpha-aminoadipate kinase [EC:2.7.2.8 2.7.2.-]
E        K05829  lysY; N-acetyl-gamma-glutamyl-phosphate/LysW-gamma-L-alpha-aminoadipyl-6-phosphate reductase [EC:1.2.1.38 1.2.1.-]
E        K12659  ARG56; N-acetyl-gamma-glutamyl-phosphate reductase / acetylglutamate kinase [EC:1.2.1.38 2.7.2.8]
E        K00818  E2.6.1.11, argD; acetylornithine aminotransferase [EC:2.6.1.11]
E        K00821  argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
E        K05830  lysJ; acetylornithine/LysW-gamma-L-lysine aminotransferase [EC:2.6.1.11 2.6.1.-]
E        K01438  argE; acetylornithine deacetylase [EC:3.5.1.16]
E        K14677  ACY1; aminoacylase [EC:3.5.1.14]
D      M00029  Urea cycle [PATH:map00330]
E        K01948  CPS1; carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
E        K00611  OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]
E        K01940  E6.3.4.5, argG; argininosuccinate synthase [EC:6.3.4.5]
E        K01755  argH, ASL; argininosuccinate lyase [EC:4.3.2.1]
E        K14681  argHA; argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1]
E        K01476  E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]
C    Histidine metabolism
D      M00026  Histidine biosynthesis, PRPP => histidine [PATH:map00340]
E        K00765  hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
E        K02502  hisZ; ATP phosphoribosyltransferase regulatory subunit
E        K01523  hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
E        K01496  hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
E        K11755  hisIE; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase [EC:3.6.1.31 3.5.4.19]
E        K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
E        K01814  E5.3.1.16, hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
E        K02501  hisH; glutamine amidotransferase [EC:2.4.2.-]
E        K02500  hisF; cyclase [EC:4.1.3.-]
E        K01663  HIS7; glutamine amidotransferase / cyclase [EC:2.4.2.- 4.1.3.-]
E        K01693  E4.2.1.19, hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
E        K00817  hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
E        K04486  E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
E        K05602  hisN; histidinol-phosphatase [EC:3.1.3.15]
E        K01089  hisB; imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]
E        K00013  hisD; histidinol dehydrogenase [EC:1.1.1.23]
D      M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:map00340]
E        K01745  hutH, HAL; histidine ammonia-lyase [EC:4.3.1.3]
E        K01712  hutU, UROC1; urocanate hydratase [EC:4.2.1.49]
E        K01468  E3.5.2.7, hutI; imidazolonepropionase [EC:3.5.2.7]
E        K01479  E3.5.3.8, hutG; formiminoglutamase [EC:3.5.3.8]
C    Aromatic amino acid metabolism
D      M00022  Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:map00400]
E        K01626  E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
E        K03856  AROA2, aroA; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
E        K13853  aroG, aroA; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5]
E        K01735  aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
E        K13829  aroKB; shikimate kinase / 3-dehydroquinate synthase [EC:2.7.1.71 4.2.3.4]
E        K03785  aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
E        K03786  aroQ, qutE; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
E        K00014  aroE; shikimate dehydrogenase [EC:1.1.1.25]
E        K13832  aroDE, DHQ-SDH; 3-dehydroquinate dehydratase / shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25]
E        K13830  ARO1; pentafunctional AROM polypeptide [EC:4.2.3.4 4.2.1.10 1.1.1.25 2.7.1.71 2.5.1.19]
E        K00891  E2.7.1.71, aroK, aroL; shikimate kinase [EC:2.7.1.71]
E        K00800  aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
E        K01736  aroC; chorismate synthase [EC:4.2.3.5]
D      M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:map00400]
E        K01657  trpE; anthranilate synthase component I [EC:4.1.3.27]
E        K01658  trpG; anthranilate synthase component II [EC:4.1.3.27]
E        K13503  trpEG; anthranilate synthase [EC:4.1.3.27]
E        K13501  TRP1; anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24]
E        K01656  TRP3; anthranilate synthase / indole-3-glycerol phosphate synthase [EC:4.1.3.27 4.1.1.48]
E        K00766  trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
E        K13497  trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18]
E        K01817  trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
E        K01609  trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
E        K13498  trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24]
E        K01695  trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
E        K01696  trpB; tryptophan synthase beta chain [EC:4.2.1.20]
E        K06001  K06001, trpB; tryptophan synthase beta chain [EC:4.2.1.20]
E        K01694  TRP; tryptophan synthase [EC:4.2.1.20]
D      M00024  Phenylalanine biosynthesis, chorismate => phenylalanine [PATH:map00400]
E        K01850  E5.4.99.5; chorismate mutase [EC:5.4.99.5]
E        K04092  tyrA1; chorismate mutase [EC:5.4.99.5]
E        K14187  tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12]
E        K04093  pheA1; chorismate mutase [EC:5.4.99.5]
E        K04516  AROA1, aroA; chorismate mutase [EC:5.4.99.5]
E        K06208  aroH; chorismate mutase [EC:5.4.99.5]
E        K06209  pheB; chorismate mutase [EC:5.4.99.5]
E        K13853  aroG, aroA; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5]
E        K01713  pheC; cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91]
E        K04518  pheA2; prephenate dehydratase [EC:4.2.1.51]
E        K05359  ADT, PDT; arogenate/prephenate dehydratase [EC:4.2.1.91 4.2.1.51]
E        K14170  pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
E        K00832  tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
E        K00838  ARO8; aromatic amino acid aminotransferase I [EC:2.6.1.57 2.6.1.27 2.6.1.5]
D      M00025  Tyrosine biosynthesis, chorismate => tyrosine [PATH:map00400]
E        K01850  E5.4.99.5; chorismate mutase [EC:5.4.99.5]
E        K04092  tyrA1; chorismate mutase [EC:5.4.99.5]
E        K14170  pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]
E        K04093  pheA1; chorismate mutase [EC:5.4.99.5]
E        K04516  AROA1, aroA; chorismate mutase [EC:5.4.99.5]
E        K06208  aroH; chorismate mutase [EC:5.4.99.5]
E        K06209  pheB; chorismate mutase [EC:5.4.99.5]
E        K13853  aroG, aroA; 3-deoxy-7-phosphoheptulonate synthase / chorismate mutase [EC:2.5.1.54 5.4.99.5]
E        K00210  E1.3.1.12; prephenate dehydrogenase [EC:1.3.1.12]
E        K04517  tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
E        K14187  tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12]
E        K00815  TAT; tyrosine aminotransferase [EC:2.6.1.5]
E        K00832  tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
E        K00838  ARO8; aromatic amino acid aminotransferase I [EC:2.6.1.57 2.6.1.27 2.6.1.5]
D      M00040  Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine [PATH:map00400]
E        K00832  tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57]
E        K15849  PAT, AAT; bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [EC:2.6.1.1 2.6.1.78 2.6.1.79]
E        K00220  tyrC; cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12]
E        K15226  tyrAa; arogenate dehydrogenase (NADP+) [EC:1.3.1.78]
E        K15227  TYRAAT; arogenate dehydrogenase (NADP+), plant [EC:1.3.1.78]
D      M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:map00350]
E        K00505  TYR; tyrosinase [EC:1.14.18.1]
E        K00501  TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
E        K01592  E4.1.1.25; tyrosine decarboxylase [EC:4.1.1.25]
E        K01593  DDC; aromatic-L-amino-acid decarboxylase [EC:4.1.1.28]
E        K00503  DBH; dopamine beta-monooxygenase [EC:1.14.17.1]
E        K00553  PNMT; phenylethanolamine N-methyltransferase [EC:2.1.1.28]
D      M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:map00350]
E        K00431  TPO; thyroid peroxidase [EC:1.11.1.8]
D      M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:map00350]
E        K03334  IL4I1; L-amino-acid oxidase [EC:1.4.3.2]
E        K00457  HPD, hppD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
E        K00451  HGD, hmgA; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
E        K01800  maiA, GSTZ1; maleylacetoacetate isomerase [EC:5.2.1.2]
E        K01555  FAH, fahA; fumarylacetoacetase [EC:3.7.1.2]
E        K16171  faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
D      M00533  Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:map00350]
E        K00455  hpaD, hpcB; 3,4-dihydroxyphenylacetate 2,3-dioxygenase [EC:1.13.11.15]
E        K00151  hpaE, hpcC; 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:1.2.1.60]
E        K10219  ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
E        K01826  hpaF, hpcD; 5-carboxymethyl-2-hydroxymuconate isomerase [EC:5.3.3.10]
E        K05921  hpaG; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [EC:4.1.1.68 5.3.3.-]
D      M00545  Trans-cinnamate degradation, trans-cinnamate => 2-oxopent-4-enoate + fumarate [PATH:map00360]
E        K05708  hcaA1, hcaE; 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha [EC:1.14.12.19]
E        K05709  hcaA2, hcaF; 3-phenylpropionate/cinnamic acid dioxygenase subunit beta [EC:1.14.12.19]
E        K05710  hcaC, bphF; dioxygenase ferredoxin subunit
E        K00529  hcaD; ferredoxin--NAD+ reductase [EC:1.18.1.3]
E        K05711  hcaB; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase [EC:1.3.1.87]
E        K05712  mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase [EC:1.14.13.127]
E        K05713  mhpB; 2,3-dihydroxyphenylpropionate 1,2-dioxygenase [EC:1.13.11.16]
E        K05714  mhpC; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase [EC:3.7.1.-]
D      M00350  Capsaicin biosynthesis, L-Phenylalanine => Capsaicin [PATH:map00360]
E        K10775  E4.3.1.24; phenylalanine ammonia-lyase [EC:4.3.1.24]
E        K13064  PTAL; phenylalanine/tyrosine ammonia-lyase [EC:4.3.1.25]
E        K00487  CYP73A; trans-cinnamate 4-monooxygenase [EC:1.14.13.11]
E        K01904  E6.2.1.12; 4-coumarate--CoA ligase [EC:6.2.1.12]
E        K00588  E2.1.1.104; caffeoyl-CoA O-methyltransferase [EC:2.1.1.104]
D      M00037  Melatonin biosynthesis, tryptophan => serotonin => melatonin [PATH:map00380]
E        K00502  TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
E        K01593  DDC; aromatic-L-amino-acid decarboxylase [EC:4.1.1.28]
E        K00669  AANAT; arylalkylamine N-acetyltransferase [EC:2.3.1.87]
E        K00543  ASMT; acetylserotonin N-methyltransferase [EC:2.1.1.4]
D      M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:map00380]
E        K00453  E1.13.11.11, TDO2; tryptophan 2,3-dioxygenase [EC:1.13.11.11]
E        K00463  INDO; indoleamine 2,3-dioxygenase [EC:1.13.11.52]
E        K01432  AFMID; arylformamidase [EC:3.5.1.9]
E        K14263  BNA7; kynurenine formamidase [EC:3.5.1.9]
E        K07130  kynB; arylformamidase [EC:3.5.1.9]
E        K00486  KMO; kynurenine 3-monooxygenase [EC:1.14.13.9]
E        K01556  KYNU, kynU; kynureninase [EC:3.7.1.3]
E        K00452  HAAO; 3-hydroxyanthranilate 3,4-dioxygenase [EC:1.13.11.6]
E        K03392  ACMSD; aminocarboxymuconate-semialdehyde decarboxylase [EC:4.1.1.45]
E        K10217  dmpC; aminomuconate-semialdehyde dehydrogenase [EC:1.2.1.32]
C    Other amino acid metabolism
D      M00027  GABA (gamma-Aminobutyrate) shunt [PATH:map00250]
E        K01580  E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
E        K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
E        K07250  gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
E        K00823  puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
E        K16871  POP2; 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]
E        K00135  E1.2.1.16, gabD; succinate-semialdehyde dehydrogenase (NADP+) [EC:1.2.1.16]
E        K00139  ALDH5A1; succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
D      M00047  Creatine pathway [PATH:map00330]
E        K00613  GATM; glycine amidinotransferase [EC:2.1.4.1]
E        K00542  GAMT; guanidinoacetate N-methyltransferase [EC:2.1.1.2]
E        K00933  E2.7.3.2; creatine kinase [EC:2.7.3.2]
C    Cofactor and vitamin biosynthesis
D      M00127  Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P [PATH:map00730]
E        K03147  thiC; thiamine biosynthesis protein ThiC
E        K00877  THI20; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
E        K00941  thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
E        K14153  thiDE; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
E        K00878  thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
E        K14154  THI6; thiamine-phosphate diphosphorylase / hydroxyethylthiazole kinase [EC:2.5.1.3 2.7.1.50]
E        K00788  thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
E        K00946  thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D      M00125  Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD [PATH:map00740]
E        K01497  ribA, RIB1; GTP cyclohydrolase II [EC:3.5.4.25]
E        K14652  ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
E        K01498  ribD1; diaminohydroxyphosphoribosylaminopyrimidine deaminase [EC:3.5.4.26]
E        K00082  ribD2; 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:1.1.1.193]
E        K11752  ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
E        K02858  ribB, RIB3; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
E        K00794  ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
E        K00793  ribE, RIB5; riboflavin synthase [EC:2.5.1.9]
E        K00861  RFK, FMN1; riboflavin kinase [EC:2.7.1.26]
E        K00953  FLAD1; FAD synthetase [EC:2.7.7.2]
E        K11753  ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D      M00124  Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P [PATH:map00750]
E        K03472  epd; D-erythrose 4-phosphate dehydrogenase [EC:1.2.1.72]
E        K03473  pdxB; erythronate-4-phosphate dehydrogenase [EC:1.1.1.290]
E        K00831  serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]
E        K00097  pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262]
E        K03474  pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
E        K00275  pdxH, PNPO; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D      M00115  NAD biosynthesis, aspartate => NAD [PATH:map00760]
E        K00278  nadB; L-aspartate oxidase [EC:1.4.3.16]
E        K03517  nadA; quinolinate synthase [EC:2.5.1.72]
E        K00767  nadC, QPRT; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
E        K00969  nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
E        K06210  NMNAT; nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18]
E        K01916  nadE; NAD+ synthase [EC:6.3.1.5]
E        K01950  E6.3.5.1, NADSYN1, QNS1, nadE; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
D      M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:map00770]
E        K00826  E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]
E        K00606  panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
E        K00077  panE, apbA; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
E        K01579  panD; aspartate 1-decarboxylase [EC:4.1.1.11]
E        K01918  panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
E        K13799  panC-cmk; pantoate ligase / cytidylate kinase [EC:6.3.2.1 2.7.4.14]
D      M00120  Coenzyme A biosynthesis, pantothenate => CoA [PATH:map00770]
E        K00867  coaA; type I pantothenate kinase [EC:2.7.1.33]
E        K03525  coaX; type III pantothenate kinase [EC:2.7.1.33]
E        K09680  coaW; type II pantothenate kinase [EC:2.7.1.33]
E        K01947  birA-coaX; biotin-[acetyl-CoA-carboxylase] ligase / type III pantothenate kinase [EC:6.3.4.15 2.7.1.33]
E        K01922  PPCS, coaB; phosphopantothenate-cysteine ligase [EC:6.3.2.5]
E        K01598  PPCDC, coaC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]
E        K13038  coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase [EC:4.1.1.36 6.3.2.5]
E        K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
E        K00954  E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
E        K02201  E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
E        K00859  coaE; dephospho-CoA kinase [EC:2.7.1.24]
D      M00572  Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:map00780]
E        K02169  bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197]
E        K16592  bioCG; BioC/BioG fusion protein
E        K00647  fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
E        K09458  fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
E        K00059  fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
E        K02372  fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
E        K00208  fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
E        K02170  bioH; pimelyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85]
E        K09789  bioG; biotin synthesis protein BioG
D      M00123  Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:map00780]
E        K00652  bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
E        K00833  bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
E        K01935  bioD; dethiobiotin synthetase [EC:6.3.3.3]
E        K01012  bioB; biotin synthase [EC:2.8.1.6]
D      M00573  Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin [PATH:map00780]
E        K16593  bioI; cytochrome P450 [EC:1.14.-.-]
E        K00652  bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
E        K00833  bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
E        K01935  bioD; dethiobiotin synthetase [EC:6.3.3.3]
E        K01012  bioB; biotin synthase [EC:2.8.1.6]
D      M00577  Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:map00780]
E        K01906  bioW; 6-carboxyhexanoate--CoA ligase [EC:6.2.1.14]
E        K00652  bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
E        K00833  bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
E        K01935  bioD; dethiobiotin synthetase [EC:6.3.3.3]
E        K01012  bioB; biotin synthase [EC:2.8.1.6]
D      M00126  Tetrahydrofolate biosynthesis, GTP => THF [PATH:map00790 map00670]
E        K01495  folE; GTP cyclohydrolase I [EC:3.5.4.16]
E        K01077  E3.1.3.1, phoA, phoB; alkaline phosphatase [EC:3.1.3.1]
E        K01113  phoD; alkaline phosphatase D [EC:3.1.3.1]
E        K13939  FOL1; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:4.1.2.25 2.7.6.3 2.5.1.15]
E        K13940  sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]
E        K00796  folP; dihydropteroate synthase [EC:2.5.1.15]
E        K01633  folB; dihydroneopterin aldolase [EC:4.1.2.25]
E        K00950  folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
E        K13941  folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
E        K11754  folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
E        K01930  E6.3.2.17; folylpolyglutamate synthase [EC:6.3.2.17]
E        K00287  folA; dihydrofolate reductase [EC:1.5.1.3]
E        K13998  DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
E        K13938  folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.- 1.5.1.3]
D      M00121  Heme biosynthesis, glutamate => protoheme/siroheme [PATH:map00860]
E        K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]
E        K14163  EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
E        K02492  hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
E        K01845  hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
E        K01698  hemB, ALAD; porphobilinogen synthase [EC:4.2.1.24]
E        K01749  hemC, HMBS; hydroxymethylbilane synthase [EC:2.5.1.61]
E        K01719  hemD, UROS; uroporphyrinogen-III synthase [EC:4.2.1.75]
E        K13542  cobA-hemD; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
E        K13543  hemDX; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
E        K01599  hemE, UROD; uroporphyrinogen decarboxylase [EC:4.1.1.37]
E        K00228  hemF, CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
E        K02495  hemN, hemZ; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.99.22]
E        K00230  hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3]
E        K00231  PPOX, hemY; oxygen-dependent protoporphyrinogen oxidase [EC:1.3.3.4]
E        K01772  hemH, FECH; ferrochelatase [EC:4.99.1.1]
E        K02302  cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
E        K00589  MET1; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
E        K02303  cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
E        K02496  hemX; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
E        K02304  MET8; precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
E        K03794  sirB; sirohydrochlorin ferrochelatase [EC:4.99.1.4]
D      M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:map00040 map00053]
E        K00963  UGP2, galU, galF; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
E        K00012  UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
E        K00699  UGT; glucuronosyltransferase [EC:2.4.1.17]
E        K01195  E3.2.1.31, GUSB, uidA; beta-glucuronidase [EC:3.2.1.31]
E        K14756  KL; klotho [EC:3.2.1.31]
E        K01053  E3.1.1.17; gluconolactonase [EC:3.1.1.17]
E        K00103  E1.1.3.8; L-gulonolactone oxidase [EC:1.1.3.8]
D      M00114  Ascorbate biosynthesis, plants, glucose-6P => ascorbate [PATH:map00010 map00051 map00053]
E        K01810  GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]
E        K06859  pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
E        K13810  tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
E        K01809  E5.3.1.8, manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
E        K16011  algA, xanB, rfbA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
E        K15916  pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
E        K16881  K16881; mannose-1-phosphate guanylyltransferase / phosphomannomutase [EC:2.7.7.13 5.4.2.8]
E        K01840  E5.4.2.8, manB; phosphomannomutase [EC:5.4.2.8]
E        K15778  pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
E        K00966  GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
E        K00971  manC, cpsB; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
E        K10046  GME; GDP-D-mannose 3', 5'-epimerase [EC:5.1.3.18 5.1.3.-]
E        K14190  VTC2_5; GDP-L-galactose phosphorylase [EC:2.7.7.69]
E        K10047  VTC4; inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase [EC:3.1.3.25 3.1.3.-]
E        K00064  E1.1.1.122; D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]
E        K00225  E1.3.2.3; L-galactono-1,4-lactone dehydrogenase [EC:1.3.2.3]
E        K05276  E1.3.3.12; L-galactonolactone oxidase [EC:1.3.3.12]
D      M00550  Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:map00053]
E        K02821  PTS-Ula-EIIA, ulaC, sgaA; PTS system, ascorbate-specific IIA component [EC:2.7.1.69]
E        K02822  PTS-Ula-EIIB, ulaB, sgaB; PTS system, ascorbate-specific IIB component [EC:2.7.1.69]
E        K03475  PTS-Ula-EIIC, ulaA, sgaT; PTS system, ascorbate-specific IIC component
E        K03476  ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]
E        K03078  ulaD, sgaH; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]
E        K03079  ulaE, sgaU; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]
E        K03077  ulaF, sgaE; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]
D      M00112  Tocopherol biosynthesis [PATH:map00130]
E        K09833  HPT, TPT; homogenitisate phytyltransferase
E        K12502  VTE3, APG1; MPBQ/MSBQ methyltransferase
E        K09834  VTE1, SXD1; tocopherol cyclase
E        K05928  E2.1.1.95; tocopherol O-methyltransferase [EC:2.1.1.95]
D      M00122  Cobalamin biosynthesis, cobinamide => cobalamin [PATH:map00860]
E        K13786  cobR; cob(II)yrinic acid a,c-diamide reductase [EC:1.16.8.1]
E        K00798  E2.5.1.17, cobO, btuR; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
E        K02232  E6.3.5.10, cobQ, cbiP; adenosylcobyric acid synthase [EC:6.3.5.10]
E        K02225  cobC1, cobC; cobalamin biosynthetic protein CobC
E        K02227  cbiB, cobD; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
E        K02231  cobP, cobU; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62]
E        K00768  E2.4.2.21, cobU, cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21]
E        K02226  cobC2, cobC, phpB; alpha-ribazole phosphatase [EC:3.1.3.73]
E        K02233  E2.7.8.26, cobS, cobV; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D      M00117  Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone [PATH:map00130]
E        K03181  ubiC; chorismate--pyruvate lyase [EC:4.1.3.40]
E        K03179  ubiA; 4-hydroxybenzoate octaprenyltransferase [EC:2.5.1.-]
E        K03186  ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX [EC:4.1.1.-]
E        K03182  ubiD; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD [EC:4.1.1.-]
E        K03688  ubiB, aarF; ubiquinone biosynthesis protein
E        K00568  ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
E        K03185  ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
E        K03183  ubiE; ubiquinone/menaquinone biosynthesis methyltransferase [EC:2.1.1.163 2.1.1.201]
E        K03184  ubiF; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [EC:1.14.13.-]
D      M00128  Ubiquinone biosynthesis, eukaryotes, chorismate => ubiquinone [PATH:map00130]
E        K03181  ubiC; chorismate--pyruvate lyase [EC:4.1.3.40]
E        K06125  COQ2; 4-hydroxybenzoate hexaprenyltransferase [EC:2.5.1.-]
E        K00591  COQ3; hexaprenyldihydroxybenzoate methyltransferase [EC:2.1.1.114]
E        K06126  COQ6; ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-]
E        K06127  COQ5; ubiquinone biosynthesis methyltransferase [EC:2.1.1.201]
E        K06134  COQ7; ubiquinone biosynthesis monooxygenase Coq7 [EC:1.14.13.-]
D      M00116  Menaquinone biosynthesis, chorismate => menaquinone [PATH:map00130]
E        K01851  pchA; salicylate biosynthesis isochorismate synthase [EC:5.4.4.2]
E        K02552  menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
E        K02361  entC; isochorismate synthase [EC:5.4.4.2]
E        K02551  menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
E        K08680  menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC:4.2.99.20]
E        K02549  menC; O-succinylbenzoate synthase [EC:4.2.1.113]
E        K01911  menE; O-succinylbenzoic acid--CoA ligase [EC:6.2.1.26]
E        K01661  menB; naphthoate synthase [EC:4.1.3.36]
E        K12073  E3.1.2.28; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [EC:3.1.2.28]
E        K02548  menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase [EC:2.5.1.74 2.5.1.-]
E        K03183  ubiE; ubiquinone/menaquinone biosynthesis methyltransferase [EC:2.1.1.163 2.1.1.201]
D      M00118  Glutathione biosynthesis, glutamate => glutathione [PATH:map00480]
E        K11204  GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
E        K11205  GCLM; glutamate--cysteine ligase regulatory subunit
E        K01919  gshA; glutamate--cysteine ligase [EC:6.3.2.2]
E        K01920  E6.3.2.3, gshB; glutathione synthase [EC:6.3.2.3]
D      M00140  C1-unit interconversion, prokaryotes [PATH:map00670]
E        K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
E        K01491  folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
E        K01938  fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D      M00141  C1-unit interconversion, eukaryotes [PATH:map00670]
E        K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
E        K00288  MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
E        K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
E        K13402  MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
C    Polyamine biosynthesis
D      M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:map00330]
E        K01583  E4.1.1.19; arginine decarboxylase [EC:4.1.1.19]
E        K01584  E4.1.1.19A, adi; arginine decarboxylase [EC:4.1.1.19]
E        K01585  E4.1.1.19S, speA; arginine decarboxylase [EC:4.1.1.19]
E        K02626  pdaD; arginine decarboxylase [EC:4.1.1.19]
E        K01480  E3.5.3.11, speB; agmatinase [EC:3.5.3.11]
E        K01611  speD, AMD1; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
E        K00797  speE, SRM; spermidine synthase [EC:2.5.1.16]
D      M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:map00330]
E        K01476  E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]
E        K01581  E4.1.1.17, ODC1, speC, speF; ornithine decarboxylase [EC:4.1.1.17]
D      M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:map00330]
E        K00657  E2.3.1.57, speG; diamine N-acetyltransferase [EC:2.3.1.57]
E        K00274  MAO, aofH; monoamine oxidase [EC:1.4.3.4]
E        K00128  E1.2.1.3; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
E        K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
E        K00149  ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
D      M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:map00330]
E        K09470  puuA; gamma-glutamylputrescine synthase [EC:6.3.1.11]
E        K09471  puuB, ordL; gamma-glutamylputrescine oxidase [EC:1.4.3.-]
E        K09472  puuC, aldH; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [EC:1.2.1.-]
E        K09473  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
C    Phenylpropanoid and flavonoid biosynthesis
D      M00039  Lignin biosynthesis, cinnamate => lignin [PATH:map00940]
E        K00487  CYP73A; trans-cinnamate 4-monooxygenase [EC:1.14.13.11]
E        K01904  E6.2.1.12; 4-coumarate--CoA ligase [EC:6.2.1.12]
E        K09753  CCR; cinnamoyl-CoA reductase [EC:1.2.1.44]
E        K00083  E1.1.1.195; cinnamyl-alcohol dehydrogenase [EC:1.1.1.195]
E        K00430  E1.11.1.7; peroxidase [EC:1.11.1.7]
E        K11188  PRDX6; peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-]
E        K03782  katG; catalase-peroxidase [EC:1.11.1.21]
D      M00137  Flavonoid biosynthesis, 4-coumaroyl-CoA => naringenin => apigenin [PATH:map00941]
E        K00660  CHS; chalcone synthase [EC:2.3.1.74]
E        K01859  E5.5.1.6; chalcone isomerase [EC:5.5.1.6]
E        K13077  FNSI; flavone synthase [EC:1.14.11.22]
D      M00138  Flavonoid biosynthesis, naringenin => pelargonidin [PATH:map00941]
E        K00475  E1.14.11.9; naringenin 3-dioxygenase [EC:1.14.11.9]
E        K13082  DFR; bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase [EC:1.1.1.219 1.1.1.234]
E        K05277  E1.14.11.19; leucoanthocyanidin dioxygenase [EC:1.14.11.19]
C    Alkaloid and other secondary metabolite biosynthesis
D      M00139  Morphine biosynthesis, dopamine => morphine [PATH:map00950]
E        K13382  NCS; (S)-norcoclaurine synthase [EC:4.2.1.78]
E        K13383  E2.1.1.128; (RS)-norcoclaurine 6-O-methyltransferase [EC:2.1.1.128]
E        K13384  E2.1.1.140; (S)-coclaurine N-methyltransferase [EC:2.1.1.140]
E        K13385  CYP80B; cytochrome P450, family 80, subfamily B (N-methylcoclaurine 3'-monooxygenase) [EC:1.14.13.71]
E        K13386  E2.1.1.116; 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase [EC:2.1.1.116]
E        K13391  CYP719B1; cytochrome P450, family 719, subfamily B, polypeptide 1 (salutaridine synthase) [EC:1.14.21.4]
E        K13392  SALR; salutaridine reductase (NADPH) [EC:1.1.1.248]
E        K13393  SALAT; salutaridinol 7-O-acetyltransferase [EC:2.3.1.150]
E        K14976  T6ODM; thebaine 6-O-demethylase [EC:1.14.11.31]
E        K13394  COR1; codeinone reductase [EC:1.1.1.247]
E        K14975  CODM; codeine 3-O-demethylase [EC:1.14.11.32]
D      M00369  Cyanogenic glycoside biosynthesis, tyrosine => dhurrin [PATH:map00460]
E        K13027  CYP79A1; tyrosine N-monooxygenase [EC:1.14.13.41]
E        K13029  CYP71E1; 4-hydroxyphenylacetaldehyde oxime monooxygenase [EC:1.14.13.68]
E        K13030  UGT85B1; cyanohydrin beta-glucosyltransferase [EC:2.4.1.85]
D      M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin [PATH:map00966]
E        K11812  CYP79B2; cytochrome P450, family 79, subfamily B, polypeptide 2 (tryptophan N-monooxygenase) [EC:1.14.13.125]
E        K11813  CYP79B3; cytochrome P450, family 79, subfamily B, polypeptide 3 (tryptophan N-monooxygenase) [EC:1.14.13.125]
E        K11818  CYP83B1; cytochrome P450, family 83, subfamily B, polypeptide 1 [EC:1.14.-.-]
E        K11819  SUR1, RTY; ROOTY/SUPERROOT1 [EC:4.4.1.-]
E        K11820  UGT74B1; N-hydroxythioamide S-beta-glucosyltransferase [EC:2.4.1.195]
E        K11821  ST5A_B_C; desulfoglucosinolate sulfotransferase A/B/C [EC:2.8.2.-]
D      M00033  Ectoine biosynthesis [PATH:map00260]
E        K00928  lysC; aspartate kinase [EC:2.7.2.4]
E        K00133  asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
E        K00836  E2.6.1.76, ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
E        K06718  ectA; L-2,4-diaminobutyric acid acetyltransferase [EC:2.3.1.178]
E        K06720  ectC; L-ectoine synthase [EC:4.2.1.108]
B
B  <b>Secondary metabolism</b>
C    Aromatics degradataion
D      M00538  Toluene degradation, toluene => benzoate [PATH:map00623]
E        K15760  tmoA, tbuA1, touA; toluene monooxygenase system protein A [EC:1.14.13.-]
E        K15761  tmoB, tbuU, touB; toluene monooxygenase system protein B [EC:1.14.13.-]
E        K15762  tmoC, tbuB, touC; toluene monooxygenase system ferredoxin subunit
E        K15763  tmoD, tbuV, touD; toluene monooxygenase system protein D [EC:1.14.13.-]
E        K15764  tmoE, tbuA2, touE; toluene monooxygenase system protein E [EC:1.14.13.-]
E        K15765  tmoF, tbuC, touF; toluene monooxygenase electron transfer component [EC:1.18.1.3]
E        K00055  E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90]
E        K00141  xylC; benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]
D      M00537  Xylene degradation, xylene => methylbenzoate [PATH:map00622]
E        K15757  xylM; xylene monooxygenase subunit XylM [EC:1.14.15.-]
E        K15758  cymAb, xylA; xylene monooxygenase electron transfer component [EC:1.18.1.3]
E        K00055  E1.1.1.90; aryl-alcohol dehydrogenase [EC:1.1.1.90]
E        K00141  xylC; benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28]
D      M00419  Cymene degradation, p-cymene => p-cumate [PATH:map00622]
E        K10616  cymAa; p-cymene monooxygenase [EC:1.14.13.-]
E        K15758  cymAb, xylA; xylene monooxygenase electron transfer component [EC:1.18.1.3]
E        K10617  cymB; p-cumic alcohol dehydrogenase
E        K10618  cymC; p-cumic aldehyde dehydrogenase
D      M00547  Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:map00362 map00623]
E        K03268  bedC1, todC1; benzene/toluene dioxygenase subunit alpha [EC:1.14.12.3 1.14.12.11]
E        K16268  bedC2, todC2; benzene/toluene dioxygenase subunit beta [EC:1.14.12.3 1.14.12.11]
E        K05710  hcaC, bphF; dioxygenase ferredoxin subunit
E        K00529  hcaD; ferredoxin--NAD+ reductase [EC:1.18.1.3]
E        K16269  todD; cis-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.19]
D      M00548  Benzene degradation, benzene => catechol [PATH:map00362]
E        K16249  dmpK, poxA; phenol hydroxylase P0 protein
E        K16243  dmpL, poxC; Phenol hydroxylase P1 protein
E        K16244  dmpM, poxB; phenol hydroxylase P2 protein
E        K16242  dmpN, poxD; phenol hydroxylase P3 protein [EC:1.14.13.-]
E        K16245  dmpO, poxE; phenol hydroxylase P4 protein
E        K16246  dmpP, poxF; phenol hydroxylase P5 protein
D      M00551  Benzoate degradation, benzoate => catechol [PATH:map00362 map00622]
E        K05549  benA-xylX; benzoate/toluate 1,2-dioxygenase subunit alpha [EC:1.14.12.10 1.14.12.-]
E        K05550  benB-xylY; benzoate/toluate 1,2-dioxygenase subunit beta [EC:1.14.12.10 1.14.12.-]
E        K05784  benC-xylZ; benzoate/toluate 1,2-dioxygenase electron transfer component
E        K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]
D      M00568  Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:map00362]
E        K03381  catA; catechol 1,2-dioxygenase [EC:1.13.11.1]
E        K01856  catB; muconate cycloisomerase [EC:5.5.1.1]
E        K03464  catC; muconolactone D-isomerase [EC:5.3.3.4]
E        K01055  pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
E        K14727  pcaL; 3-oxoadipate enol-lactonase / 4-carboxymuconolactone decarboxylase [EC:3.1.1.24 4.1.1.44]
D      M00569  Catechol meta-cleavage, catechol => pyruvate + acetaldehyde [PATH:map00362 map00622]
E        K00446  dmpB; catechol 2,3-dioxygenase [EC:1.13.11.2]
E        K10217  dmpC; aminomuconate-semialdehyde dehydrogenase [EC:1.2.1.32]
E        K01821  E5.3.2.-; 4-oxalocrotonate tautomerase [EC:5.3.2.-]
E        K01617  E4.1.1.77; 4-oxalocrotonate decarboxylase [EC:4.1.1.77]
E        K02554  mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80]
E        K01666  E4.1.3.39, mhpE; 4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39]
D      M00539  Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate [PATH:map00622]
E        K10619  cmtAb; p-cumate 2,3-dioxygenase subunit alpha [EC:1.14.12.-]
E        K16303  cmtAc; p-cumate 2,3-dioxygenase subunit beta [EC:1.14.12.-]
E        K05710  hcaC, bphF; dioxygenase ferredoxin subunit
E        K00529  hcaD; ferredoxin--NAD+ reductase [EC:1.18.1.3]
E        K10620  cmtB; 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase [EC:1.3.1.58]
E        K10621  cmtC, dhbA; 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase [EC:1.13.11.- 1.13.11.14]
E        K10622  cmtD, dhbB; HCOMODA/2-hydroxy-3-carboxy-muconic semialdehyde decarboxylase [EC:4.1.1.-]
E        K10623  cmtE; HOMODA hydrolase [EC:3.7.1.-]
D      M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate [PATH:map00621]
E        K08689  bphA; biphenyl 2,3-dioxygenase subunit alpha [EC:1.14.12.18]
E        K15750  bphE; biphenyl 2,3-dioxygenase subunit beta [EC:1.14.12.18]
E        K05710  hcaC, bphF; dioxygenase ferredoxin subunit
E        K00529  hcaD; ferredoxin--NAD+ reductase [EC:1.18.1.3]
E        K08690  bphB; cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [EC:1.3.1.56]
E        K00462  bphC; biphenyl-2,3-diol 1,2-dioxygenase [EC:1.13.11.39]
E        K10222  bphD; 2,6-dioxo-6-phenylhexa-3-enoate hydrolase [EC:3.7.1.8]
D      M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate [PATH:map00621]
E        K15751  carAa; carbazole 1,9a-dioxygenase, terminal dioxygenase component [EC:1.14.12.22]
E        K15752  carAc; carbazole 1,9a-dioxygenase, ferredoxin component
E        K15753  carAd; carbazole 1,9a-dioxygenase, ferredoxin reductase component
E        K15754  carBa; 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, small subunit [EC:1.13.11.-]
E        K15755  carBb; 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, large subunit [EC:1.13.11.-]
E        K15756  carC; 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase [EC:3.7.1.-]
D      M00418  Toluene degradation, anaerobic, toluene => benzoyl-CoA [PATH:map00623]
E        K07540  E4.1.99.11; benzylsuccinate synthase [EC:4.1.99.11]
E        K07543  bbsE; benzylsuccinate CoA-transferase BbsE subunit [EC:2.8.3.15]
E        K07544  bbsF; benzylsuccinate CoA-transferase BbsF subunit [EC:2.8.3.15]
E        K07545  bbsG; (R)-benzylsuccinyl-CoA dehydrogenase [EC:1.3.8.3]
E        K07546  bbsH; E-phenylitaconyl-CoA hydratase [EC:4.2.1.-]
E        K07547  bbsC; 2-[hydroxy(phenyl)methyl]-succinyl-CoA dehydrogenase BbsC subunit [EC:1.1.1.35]
E        K07548  bbsD; 2-[hydroxy(phenyl)methyl]-succinyl-CoA dehydrogenase BbsD subunit [EC:1.1.1.35]
E        K07549  bbsA; benzoylsuccinyl-CoA thiolase BbsA subunit [EC:2.3.1.-]
E        K07550  bbsB; benzoylsuccinyl-CoA thiolase BbsB subunit [EC:2.3.1.-]
D      M00541  Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA [PATH:map00362]
E        K04112  badD; benzoyl-CoA reductase subunit [EC:1.3.7.8]
E        K04113  badE; benzoyl-CoA reductase subunit [EC:1.3.7.8]
E        K04114  badF; benzoyl-CoA reductase subunit [EC:1.3.7.8]
E        K04115  badG; benzoyl-CoA reductase subunit [EC:1.3.7.8]
E        K07537  dch; cyclohexa-1,5-dienecarbonyl-CoA hydratase [EC:4.2.1.100]
E        K07538  had; 6-hydroxycyclohex-1-ene-1-carboxyl-CoA dehydrogenase [EC:1.1.1.-]
E        K07539  oah; 6-oxo-cyclohex-1-ene-carbonyl-CoA hydrolase [EC:3.7.1.-]
D      M00540  Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA [PATH:map00362]
E        K04116  aliA; cyclohexanecarboxylate-CoA ligase [EC:6.2.1.-]
E        K04117  aliB; cyclohexanecarboxyl-CoA dehydrogenase [EC:1.3.99.-]
E        K07534  badK; cyclohex-1-ene-1-carboxyl-CoA hydratase [EC:4.2.1.-]
E        K07535  badH; 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [EC:1.1.1.-]
E        K07536  badI; 2-ketocyclohexanecarboxyl-CoA hydrolase [EC:3.1.2.-]
D      M00534  Naphthalene degradataion, naphthalene => salicylate [PATH:map00626]
E        K14579  nahAc, ndoB; naphthalene 1,2-dioxygenase subunit alpha [EC:1.14.12.12]
E        K14580  nahAd, ndoC; naphthalene 1,2-dioxygenase subunit beta [EC:1.14.12.12]
E        K14578  nahAb, ndoA; naphthalene 1,2-dioxygenase system ferredoxin subunit
E        K14581  nahAa, ndoR; naphthalene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component [EC:1.18.1.3]
E        K14582  nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase [EC:1.3.1.29 1.3.1.60]
E        K14583  nahC; 1,2-dihydroxynaphthalene dioxygenase [EC:1.13.11.56]
E        K14584  nahD; 2-hydroxychromene-2-carboxylate isomerase [EC:5.99.1.4]
E        K14585  nahE; trans-o-hydroxybenzylidenepyruvate hydratase-aldolase [EC:4.1.2.45]
E        K00152  E1.2.1.65; salicylaldehyde dehydrogenase [EC:1.2.1.65]
#
A<b>Structural complex</b>
B
B  <b>Energy metabolism</b>
C    Photosynthesis
D      M00161  Photosystem II [PATH:map00195]
E        K02703  psbA; photosystem II P680 reaction center D1 protein
E        K02706  psbD; photosystem II P680 reaction center D2 protein
E        K02705  psbC; photosystem II CP43 chlorophyll apoprotein
E        K02704  psbB; photosystem II CP47 chlorophyll apoprotein
E        K02707  psbE; photosystem II cytochrome b559 subunit alpha
E        K02708  psbF; photosystem II cytochrome b559 subunit beta
E        K02713  psbL; photosystem II PsbL protein
E        K02711  psbJ; photosystem II PsbJ protein
E        K02709  psbH; photosystem II PsbH protein
E        K02710  psbI; photosystem II PsbI protein
E        K02712  psbK; photosystem II PsbK protein
E        K02714  psbM; photosystem II PsbM protein
E        K02718  psbT; photosystem II PsbT protein
E        K02724  psbZ; photosystem II PsbZ protein
E        K02723  psbY; photosystem II PsbY protein
E        K08902  psb27; photosystem II Psb27 protein
E        K08903  psb28; photosystem II 13kDa protein
E        K02716  psbO; photosystem II oxygen-evolving enhancer protein 1
E        K02717  psbP; photosystem II oxygen-evolving enhancer protein 2
E        K08901  psbQ; photosystem II oxygen-evolving enhancer protein 3
E        K03541  psbR; photosystem II 10kDa protein
E        K03542  psbS; photosystem II 22kDa protein
E        K02721  psbW; photosystem II PsbW protein
E        K02720  psbV; photosystem II cytochrome c550
E        K02719  psbU; photosystem II PsbU protein
E        K02722  psbX; photosystem II PsbX protein
E        K08904  psb28-2; photosystem II Psb28-2 protein
D      M00162  Cytochrome b6f complex [PATH:map00195]
E        K02635  petB; cytochrome b6
E        K02637  petD; cytochrome b6-f complex subunit 4
E        K02634  petA; apocytochrome f
E        K02636  petC; cytochrome b6-f complex iron-sulfur subunit [EC:1.10.9.1]
E        K02642  petL; cytochrome b6-f complex subunit 6
E        K02643  petM; cytochrome b6-f complex subunit 7
E        K03689  petN; cytochrome b6-f complex subunit 8
E        K02640  petG; cytochrome b6-f complex subunit 5
D      M00163  Photosystem I [PATH:map00195]
E        K02689  psaA; photosystem I P700 chlorophyll a apoprotein A1
E        K02690  psaB; photosystem I P700 chlorophyll a apoprotein A2
E        K02691  psaC; photosystem I subunit VII
E        K02692  psaD; photosystem I subunit II
E        K02693  psaE; photosystem I subunit IV
E        K02694  psaF; photosystem I subunit III
E        K02697  psaJ; photosystem I subunit IX
E        K02699  psaL; photosystem I subunit XI
E        K02696  psaI; photosystem I subunit VIII
E        K02698  psaK; photosystem I subunit X
E        K02700  psaM; photosystem I subunit XII
E        K02701  psaN; photosystem I subunit PsaN
E        K08905  psaG; photosystem I subunit V
E        K02695  psaH; photosystem I subunit VI
E        K02702  psaX; photosystem I 4.8kDa protein
D      M00164  ATP synthase [PATH:map00195]
E        K02112  ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
E        K02111  ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]
E        K02115  ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14]
E        K02113  ATPF1D, atpH; F-type H+-transporting ATPase subunit delta [EC:3.6.3.14]
E        K02114  ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14]
E        K02110  ATPF0C, atpE; F-type H+-transporting ATPase subunit c [EC:3.6.3.14]
E        K02108  ATPF0A, atpB; F-type H+-transporting ATPase subunit a [EC:3.6.3.14]
E        K02109  ATPF0B, atpF; F-type H+-transporting ATPase subunit b [EC:3.6.3.14]
C    ATP synthesis
D      M00144  NADH:quinone oxidoreductase, prokaryotes [PATH:map00190]
E        K00330  nuoA; NADH-quinone oxidoreductase subunit A [EC:1.6.5.3]
E        K00331  nuoB; NADH-quinone oxidoreductase subunit B [EC:1.6.5.3]
E        K00332  nuoC; NADH-quinone oxidoreductase subunit C [EC:1.6.5.3]
E        K00333  nuoD; NADH-quinone oxidoreductase subunit D [EC:1.6.5.3]
E        K13378  nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:1.6.5.3]
E        K13380  nuoBCD; NADH-quinone oxidoreductase subunit B/C/D [EC:1.6.5.3]
E        K00334  nuoE; NADH-quinone oxidoreductase subunit E [EC:1.6.5.3]
E        K00335  nuoF; NADH-quinone oxidoreductase subunit F [EC:1.6.5.3]
E        K00336  nuoG; NADH-quinone oxidoreductase subunit G [EC:1.6.5.3]
E        K00337  nuoH; NADH-quinone oxidoreductase subunit H [EC:1.6.5.3]
E        K00338  nuoI; NADH-quinone oxidoreductase subunit I [EC:1.6.5.3]
E        K00339  nuoJ; NADH-quinone oxidoreductase subunit J [EC:1.6.5.3]
E        K00340  nuoK; NADH-quinone oxidoreductase subunit K [EC:1.6.5.3]
E        K00341  nuoL; NADH-quinone oxidoreductase subunit L [EC:1.6.5.3]
E        K00342  nuoM; NADH-quinone oxidoreductase subunit M [EC:1.6.5.3]
E        K15863  nuoLM; NADH-quinone oxidoreductase subunit L/M [EC:1.6.5.3]
E        K00343  nuoN; NADH-quinone oxidoreductase subunit N [EC:1.6.5.3]
D      M00145  NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria [PATH:map00190]
E        K05574  ndhC; NAD(P)H-quinone oxidoreductase subunit 3 [EC:1.6.5.3]
E        K05582  ndhK; NAD(P)H-quinone oxidoreductase subunit K [EC:1.6.5.3]
E        K05581  ndhJ; NAD(P)H-quinone oxidoreductase subunit J [EC:1.6.5.3]
E        K05579  ndhH; NAD(P)H-quinone oxidoreductase subunit H [EC:1.6.5.3]
E        K05572  ndhA; NAD(P)H-quinone oxidoreductase subunit 1 [EC:1.6.5.3]
E        K05580  ndhI; NAD(P)H-quinone oxidoreductase subunit I [EC:1.6.5.3]
E        K05578  ndhG; NAD(P)H-quinone oxidoreductase subunit 6 [EC:1.6.5.3]
E        K05576  ndhE; NAD(P)H-quinone oxidoreductase subunit 4L [EC:1.6.5.3]
E        K05577  ndhF; NAD(P)H-quinone oxidoreductase subunit 5 [EC:1.6.5.3]
E        K05575  ndhD; NAD(P)H-quinone oxidoreductase subunit 4 [EC:1.6.5.3]
E        K05573  ndhB; NAD(P)H-quinone oxidoreductase subunit 2 [EC:1.6.5.3]
E        K05583  ndhL; NAD(P)H-quinone oxidoreductase subunit L [EC:1.6.5.3]
E        K05584  ndhM; NAD(P)H-quinone oxidoreductase subunit M [EC:1.6.5.3]
E        K05585  ndhN; NAD(P)H-quinone oxidoreductase subunit N [EC:1.6.5.3]
D      M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:map00190]
E        K03878  ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3]
E        K03879  ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3]
E        K03880  ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3]
E        K03881  ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3]
E        K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3]
E        K03883  ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3]
E        K03884  ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3]
D      M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:map00190]
E        K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
E        K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
E        K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
E        K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4 [EC:1.6.5.3 1.6.99.3]
E        K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5 [EC:1.6.5.3 1.6.99.3]
E        K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6 [EC:1.6.5.3 1.6.99.3]
E        K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
E        K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
E        K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
E        K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
E        K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3 [EC:1.6.5.3 1.6.99.3]
D      M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:map00190]
E        K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 [EC:1.6.5.3 1.6.99.3]
E        K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2 [EC:1.6.5.3 1.6.99.3]
E        K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 3 [EC:1.6.5.3 1.6.99.3]
E        K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 [EC:1.6.5.3 1.6.99.3]
E        K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 5 [EC:1.6.5.3 1.6.99.3]
E        K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 6 [EC:1.6.5.3 1.6.99.3]
E        K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 7 [EC:1.6.5.3 1.6.99.3]
E        K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 8 [EC:1.6.5.3 1.6.99.3]
E        K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9 [EC:1.6.5.3 1.6.99.3]
E        K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10 [EC:1.6.5.3 1.6.99.3]
E        K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 [EC:1.6.5.3 1.6.99.3]
E        K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11 [EC:1.6.5.3]
E        K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 12 [EC:1.6.5.3 1.6.99.3]
E        K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 13 [EC:1.6.5.3 1.6.99.3]
D      M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:map00190]
E        K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 1 [EC:1.6.5.3 1.6.99.3]
E        K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 2 [EC:1.6.5.3 1.6.99.3]
E        K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 [EC:1.6.5.3 1.6.99.3]
E        K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4 [EC:1.6.5.3 1.6.99.3]
E        K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5 [EC:1.6.5.3 1.6.99.3]
E        K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 6 [EC:1.6.5.3 1.6.99.3]
E        K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 7 [EC:1.6.5.3 1.6.99.3]
E        K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 [EC:1.6.5.3 1.6.99.3]
E        K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 9 [EC:1.6.5.3 1.6.99.3]
E        K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 10 [EC:1.6.5.3 1.6.99.3]
E        K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 [EC:1.6.5.3 1.6.99.3]
E        K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subcomplex unknown 1 [EC:1.6.5.3 1.6.99.3]
E        K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subcomplex unknown 2 [EC:1.6.5.3 1.6.99.3]
D      M00149  Succinate dehydrogenase, prokaryotes [PATH:map00190]
E        K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
E        K00242  sdhD; succinate dehydrogenase membrane anchor subunit
E        K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
E        K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
D      M00150  Fumarate reductase, prokaryotes [PATH:map00190]
E        K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
E        K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
E        K00246  frdC; fumarate reductase subunit C
E        K00247  frdD; fumarate reductase subunit D
D      M00148  Succinate dehydrogenase (ubiquinone) [PATH:map00190]
E        K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
E        K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
E        K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
E        K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
D      M00151  Cytochrome bc1 complex respiratory unit [PATH:map00190]
E        K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
E        K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
E        K00410  fbcH; ubiquinol-cytochrome c reductase cytochrome b/c1 subunit
E        K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
E        K03886  MQCRA, qcrA, bfcA, petC; menaquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.-]
E        K03887  MQCRB, qcrB, bfcB, petB; menaquinol-cytochrome c reductase cytochrome b subunit
E        K03888  MQCRC, qcrC, bfcC, petD; menaquinol-cytochrome c reductase cytochrome b/c subunit
E        K03890  qcrA; ubiquinol-cytochrome c reductase iron-sulfur subunit
E        K03891  qcrB; ubiquinol-cytochrome c reductase cytochrome b subunit
E        K03889  qcrC; ubiquinol-cytochrome c reductase cytochrome c subunit
D      M00152  Cytochrome bc1 complex [PATH:map00190]
E        K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
E        K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
E        K00410  fbcH; ubiquinol-cytochrome c reductase cytochrome b/c1 subunit
E        K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
E        K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
E        K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
E        K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
E        K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
E        K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
E        K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
E        K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
D      M00154  Cytochrome c oxidase [PATH:map00190]
E        K02257  COX10; protoheme IX farnesyltransferase [EC:2.5.1.-]
E        K02262  COX3; cytochrome c oxidase subunit 3
E        K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
E        K02261  COX2; cytochrome c oxidase subunit 2
E        K02263  COX4; cytochrome c oxidase subunit 4
E        K02264  COX5A; cytochrome c oxidase subunit 5a
E        K02265  COX5B; cytochrome c oxidase subunit 5b
E        K02266  COX6A; cytochrome c oxidase subunit 6a
E        K02267  COX6B; cytochrome c oxidase subunit 6b
E        K02268  COX6C; cytochrome c oxidase subunit 6c
E        K02269  COX7; cytochrome c oxidase subunit 7
E        K02270  COX7A; cytochrome c oxidase subunit 7a
E        K02271  COX7B; cytochrome c oxidase subunit 7b
E        K02272  COX7C; cytochrome c oxidase subunit 7c
E        K02273  COX8; cytochrome c oxidase subunit 8
E        K02258  COX11; cytochrome c oxidase assembly protein subunit 11
E        K02259  COX15; cytochrome c oxidase assembly protein subunit 15
E        K02260  COX17; cytochrome c oxidase assembly protein subunit 17
D      M00155  Cytochrome c oxidase, prokaryotes [PATH:map00190]
E        K02275  coxB; cytochrome c oxidase subunit II [EC:1.9.3.1]
E        K02274  coxA; cytochrome c oxidase subunit I [EC:1.9.3.1]
E        K02276  coxC; cytochrome c oxidase subunit III [EC:1.9.3.1]
E        K15408  coxAC; cytochrome c oxidase subunit I+III [EC:1.9.3.1]
E        K02277  coxD, ctaF; cytochrome c oxidase subunit IV [EC:1.9.3.1]
D      M00153  Cytochrome d ubiquinol oxidase [PATH:map00190]
E        K00425  cydA; cytochrome d ubiquinol oxidase subunit I [EC:1.10.3.-]
E        K00426  cydB; cytochrome d ubiquinol oxidase subunit II [EC:1.10.3.-]
D      M00417  Cytochrome o ubiquinol oxidase [PATH:map00190]
E        K02297  cyoA; cytochrome o ubiquinol oxidase subunit II [EC:1.10.3.-]
E        K02298  cyoB; cytochrome o ubiquinol oxidase subunit I [EC:1.10.3.-]
E        K02299  cyoC; cytochrome o ubiquinol oxidase subunit III [EC:1.10.3.-]
E        K02300  cyoD; cytochrome o ubiquinol oxidase operon protein cyoD
D      M00416  Cytochrome aa3-600 menaquinol oxidase [PATH:map00190]
E        K02827  qoxB; cytochrome aa3-600 menaquinol oxidase subunit I [EC:1.10.3.12]
E        K02826  qoxA; cytochrome aa3-600 menaquinol oxidase subunit II [EC:1.10.3.12]
E        K02828  qoxC; cytochrome aa3-600 menaquinol oxidase subunit III [EC:1.10.3.12]
E        K02829  qoxD; cytochrome aa3-600 menaquinol oxidase subunit IV [EC:1.10.3.12]
D      M00156  Cytochrome c oxidase, cbb3-type [PATH:map00190]
E        K00404  ccoN; cytochrome c oxidase cbb3-type subunit I [EC:1.9.3.1]
E        K00405  ccoO; cytochrome c oxidase cbb3-type subunit II
E        K15862  ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:1.9.3.1]
E        K00407  ccoQ; cytochrome c oxidase cbb3-type subunit IV
E        K00406  ccoP; cytochrome c oxidase cbb3-type subunit III
D      M00157  F-type ATPase, bacteria [PATH:map00190]
E        K02112  ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
E        K02111  ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]
E        K02115  ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14]
E        K02113  ATPF1D, atpH; F-type H+-transporting ATPase subunit delta [EC:3.6.3.14]
E        K02114  ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14]
E        K02110  ATPF0C, atpE; F-type H+-transporting ATPase subunit c [EC:3.6.3.14]
E        K02108  ATPF0A, atpB; F-type H+-transporting ATPase subunit a [EC:3.6.3.14]
E        K02109  ATPF0B, atpF; F-type H+-transporting ATPase subunit b [EC:3.6.3.14]
D      M00158  F-type ATPase, eukaryotes [PATH:map00190]
E        K02133  ATPeF1B, ATP5B; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
E        K02132  ATPeF1A, ATP5A1; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]
E        K02136  ATPeF1G, ATP5C1; F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14]
E        K02137  ATPeF1O, ATP5O; F-type H+-transporting ATPase oligomycin sensitivity conferral protein [EC:3.6.3.14]
E        K02134  ATPeF1D, ATP5D; F-type H+-transporting ATPase subunit delta [EC:3.6.3.14]
E        K02135  ATPeF1E, ATP5E; F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14]
E        K02128  ATPeF0C, ATP5G; F-type H+-transporting ATPase subunit c [EC:3.6.3.14]
E        K02126  ATPeF0A, MTATP6; F-type H+-transporting ATPase subunit a [EC:3.6.3.14]
E        K02127  ATPeF0B, ATP5F1; F-type H+-transporting ATPase subunit b [EC:3.6.3.14]
E        K02125  ATPeF08, MTATP8; F-type H+-transporting ATPase subunit 8 [EC:3.6.3.14]
E        K02138  ATPeFD, ATP5H; F-type H+-transporting ATPase subunit d [EC:3.6.3.14]
E        K02140  ATPeFG, ATP5L; F-type H+-transporting ATPase subunit g [EC:3.6.3.14]
E        K02129  ATPeF0E, ATP5I; F-type H+-transporting ATPase subunit e [EC:3.6.3.14]
E        K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6 [EC:3.6.3.14]
E        K02130  ATPeF0F, ATP5J2; F-type H+-transporting ATPase subunit f [EC:3.6.3.14]
E        K02139  ATPeFF, ATP17; F-type H+-transporting ATPase subunit f [EC:3.6.3.14]
E        K02141  ATPeFH, ATP14; F-type H+-transporting ATPase subunit h [EC:3.6.3.14]
E        K02142  ATPeFJ, ATP18; F-type H+-transporting ATPase subunit j [EC:3.6.3.14]
E        K02143  ATPeFK, ATP19; F-type H+-transporting ATPase subunit k [EC:3.6.3.14]
D      M00159  V-type ATPase, prokaryotes [PATH:map00190]
E        K02117  ATPVA, ntpA; V-type H+-transporting ATPase subunit A [EC:3.6.3.14]
E        K02118  ATPVB, ntpB; V-type H+-transporting ATPase subunit B [EC:3.6.3.14]
E        K02119  ATPVC, ntpC; V-type H+-transporting ATPase subunit C [EC:3.6.3.14]
E        K02120  ATPVD, ntpD; V-type H+-transporting ATPase subunit D [EC:3.6.3.14]
E        K02121  ATPVE, ntpE; V-type H+-transporting ATPase subunit E [EC:3.6.3.14]
E        K02122  ATPVF, ntpF; V-type H+-transporting ATPase subunit F [EC:3.6.3.14]
E        K02123  ATPVI, ntpI; V-type H+-transporting ATPase subunit I [EC:3.6.3.14]
E        K02124  ATPVK, ntpK; V-type H+-transporting ATPase subunit K [EC:3.6.3.14]
D      M00160  V-type ATPase, eukaryotes [PATH:map00190]
E        K02145  ATPeVA, ATP6A1; V-type H+-transporting ATPase subunit A [EC:3.6.3.14]
E        K02147  ATPeVB, ATP6B1; V-type H+-transporting ATPase subunit B [EC:3.6.3.14]
E        K02148  ATPeVC, ATP6C; V-type H+-transporting ATPase subunit C [EC:3.6.3.14]
E        K02149  ATPeVD, ATP6M; V-type H+-transporting ATPase subunit D [EC:3.6.3.14]
E        K02150  ATPeVE, ATP6E; V-type H+-transporting ATPase subunit E [EC:3.6.3.14]
E        K02151  ATPeVF, ATP6S14; V-type H+-transporting ATPase subunit F [EC:3.6.3.14]
E        K02152  ATPeVG, ATP6G1; V-type H+-transporting ATPase subunit G [EC:3.6.3.14]
E        K02153  ATPeVH, ATP6H; V-type H+-transporting ATPase subunit H [EC:3.6.3.14]
E        K02154  ATPeVI, ATP6N1A; V-type H+-transporting ATPase subunit I [EC:3.6.3.14]
E        K02146  ATPeVAC39, ATP6D; V-type H+-transporting ATPase subunit AC39 [EC:3.6.3.14]
E        K02144  ATPeV54kD; V-type H+-transporting ATPase 54 kD subunit [EC:3.6.3.14]
E        K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit [EC:3.6.3.14]
E        K02155  ATPeVPL, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit [EC:3.6.3.14]
E        K03661  ATPeVPF, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit [EC:3.6.3.14]
B
B  <b>Carbohydrate and lipid metabolism</b>
C    Carbohydrate metabolism
D      M00310  Pyruvate:ferredoxin oxidoreductase [PATH:map00620]
E        K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
E        K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
E        K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
E        K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
D      M00311  2-oxoglutarate:ferredoxin oxidoreductase [PATH:map00020]
E        K00174  korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3]
E        K00175  korB; 2-oxoglutarate ferredoxin oxidoreductase subunit beta [EC:1.2.7.3]
E        K00176  korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
E        K00177  korG; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D      M00312  2-oxoisovalerate:ferredoxin oxidoreductase [PATH:map00280]
E        K00186  vorA; 2-oxoisovalerate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.7]
E        K00187  vorB; 2-oxoisovalerate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.7]
E        K00188  vorD; 2-oxoisovalerate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.7]
E        K00189  vorG; 2-oxoisovalerate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.7]
D      M00313  indolepyruvate:ferredoxin oxidoreductase
E        K00179  iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
E        K00180  iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
E        K04090  E1.2.7.8; indolepyruvate ferredoxin oxidoreductase [EC:1.2.7.8]
C    Glycan metabolism
D      M00072  Oligosaccharyltransferase [PATH:map00510]
E        K07151  STT3; dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18]
E        K12666  OST1, RPN1; oligosaccharyltransferase complex subunit alpha (ribophorin I)
E        K12667  SWP1, RPN2; oligosaccharyltransferase complex subunit delta (ribophorin II)
E        K12668  OST2, DAD1; oligosaccharyltransferase complex subunit epsilon
E        K12669  OST3, OST6; oligosaccharyltransferase complex subunit gamma
E        K12670  WBP1; oligosaccharyltransferase complex subunit beta
E        K00730  OST4; oligosaccharyl transferase complex subunit OST4
E        K12691  OST5; oligosaccharyl transferase complex subunit OST5
B
B  <b>Genetic information processing</b>
C    DNA polymerase
D      M00260  DNA polymerase III complex, bacteria [PATH:map03030 map03430 map03440] [BR:ko03032 ko03400]
E        K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E        K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E        K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E        K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
E        K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E        K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E        K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E        K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E        K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E        K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E        K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
D      M00264  DNA polymerase II complex, archaea [BR:ko03032]
E        K02322  DPB1; DNA polymerase II large subunit [EC:2.7.7.7]
E        K02323  DPB2; DNA polymerase II small subunit [EC:2.7.7.7]
D      M00261  DNA polymerase alpha / primase complex [PATH:map03030] [BR:ko03032]
E        K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
E        K02321  POLA2; DNA polymerase alpha subunit B
E        K02685  PRI2; DNA primase large subunit [EC:2.7.7.-]
E        K02684  PRI1; DNA primase small subunit [EC:2.7.7.-]
D      M00262  DNA polymerase delta complex [PATH:map03030 map03410 map03420] [BR:ko03032 ko03400]
E        K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E        K02328  POLD2; DNA polymerase delta subunit 2
E        K03504  POLD3; DNA polymerase delta subunit 3
E        K03505  POLD4; DNA polymerase delta subunit 4
D      M00263  DNA polymerase epsilon complex [PATH:map03030] [BR:ko03032 ko03400]
E        K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
E        K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E        K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E        K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
D      M00293  DNA polymerase zeta  complex [PATH:map03460] [BR:ko03400]
E        K02350  POLZ1, rev3; DNA polymerase zeta [EC:2.7.7.7]
E        K03508  POLZ2, rev7; DNA polymerase zeta [EC:2.7.7.7]
E        K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
D      M00294  DNA polymerase gamma complex [BR:ko03032]
E        K02332  POLG1; DNA polymerase gamma 1 [EC:2.7.7.7]
E        K02333  POLG2; DNA polymerase gamma 2
C    Replication system
D      M00284  Origin recognition complex [PATH:map04110 map04111 map04113] [BR:ko03032]
E        K02603  ORC1; origin recognition complex subunit 1
E        K02604  ORC2; origin recognition complex subunit 2
E        K02605  ORC3; origin recognition complex subunit 3
E        K02606  ORC4; origin recognition complex subunit 4
E        K02607  ORC5; origin recognition complex subunit 5
E        K02608  ORC6; origin recognition complex subunit 6
D      M00285  MCM complex [PATH:map03030 map04110 map04111 map04113] [BR:ko03032]
E        K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
E        K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
E        K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
E        K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
E        K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
E        K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
D      M00286  GINS complex [BR:ko03032]
E        K10732  GINS1, PSF1; GINS complex subunit 1
E        K10733  GINS2, PSF2; GINS complex subunit 2
E        K10734  GINS3; GINS complex subunit 3
E        K10735  GINS4, SLD5; GINS complex subunit 4
D      M00288  RPA complex [PATH:map03030 map03420 map03430 map03440] [BR:ko03032 ko03400]
E        K07466  RFA1, RPA1, rpa; replication factor A1
E        K10739  RFA2, RPA2; replication factor A2
E        K10741  RPA4; replication factor A4
E        K10740  RPA3; replication factor A3
D      M00289  RF-C complex [PATH:map03030 map03420 map03430] [BR:ko03032 ko03400]
E        K10754  RFC1; replication factor C subunit 1
E        K10755  RFC2_4; replication factor C subunit 2/4
E        K10756  RFC3_5; replication factor C subunit 3/5
D      M00424  Shelterin complex [BR:ko03032]
E        K11109  POT1; protection of telomeres protein 1
E        K11110  TERF1, TRF1; telomeric repeat-binding factor 1
E        K11111  TERF2, TRF2; telomeric repeat-binding factor 2
E        K11112  TINF2, TIN2; TERF1-interacting nuclear factor 2
E        K11113  TERF2IP, RAP1; telomeric repeat-binding factor 2-interacting protein 1
E        K11114  ACD, TPP1; adrenocortical dysplasia protein
C    Repair system
D      M00296  BER complex [PATH:map03410] [BR:ko03400]
E        K10803  XRCC1; DNA-repair protein XRCC1
E        K10798  PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
E        K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E        K03512  POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E        K10981  POL4; DNA polymerase IV [EC:2.7.7.7]
E        K10776  LIG3; DNA ligase 3 [EC:6.5.1.1]
E        K10771  APEX1; AP endonuclease 1 [EC:4.2.99.18]
E        K10772  APEX2; AP endonuclease 2 [EC:4.2.99.18]
D      M00290  Holo-TFIIH complex [PATH:map03420] [BR:ko03021 ko03400]
E        K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
E        K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
E        K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
E        K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
E        K10843  ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
E        K10844  ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
E        K10845  TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
E        K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E        K06634  CCNH; cyclin H
E        K10842  MNAT1; CDK-activating kinase assembly factor MAT1
D      M00291  MRN complex [PATH:map03440] [BR:ko03032 ko03400]
E        K10865  MRE11; double-strand break repair protein MRE11
E        K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E        K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
D      M00292  MRX complex [PATH:map03440 map03450] [BR:ko03400]
E        K10865  MRE11; double-strand break repair protein MRE11
E        K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E        K10868  XRS2; DNA repair protein XRS2
D      M00297  DNA-PK complex [PATH:map03450 map04110] [BR:ko03032 ko03400]
E        K10884  XRCC6, KU70, G22P1; ATP-dependent DNA helicase 2 subunit 1
E        K10885  XRCC5, KU80, G22P2; ATP-dependent DNA helicase 2 subunit 2
E        K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D      M00295  BRCA1-associated genome surveillance complex (BASC) [PATH:map03430 map03440 map03460] [BR:ko03400]
E        K10605  BRCA1; breast cancer type 1 susceptibility protein
E        K08735  MSH2; DNA mismatch repair protein MSH2
E        K08737  MSH6; DNA mismatch repair protein MSH6
E        K08734  MLH1; DNA mismatch repair protein MLH1
E        K10858  PMS2; DNA mismatch repair protein PMS2
E        K10754  RFC1; replication factor C subunit 1
E        K10755  RFC2_4; replication factor C subunit 2/4
E        K10756  RFC3_5; replication factor C subunit 3/5
E        K04802  PCNA; proliferating cell nuclear antigen
E        K10865  MRE11; double-strand break repair protein MRE11
E        K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E        K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
E        K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:3.6.4.12]
E        K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
D      M00413  FA core complex [PATH:map03460] [BR:ko03400]
E        K10888  FANCA; fanconi anemia group A protein
E        K10889  FANCB; fanconi anemia group B protein
E        K10890  FANCC; fanconi anemia group C protein
E        K10892  FANCE; fanconi anemia group E protein
E        K10893  FANCF; fanconi anemia group F protein
E        K10894  FANCG; fanconi anemia group G protein
E        K10606  FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19]
E        K10896  FANCM; fanconi anemia group M protein
E        K10898  FAAP24; fanconi anemia-associated protein
E        K10993  FAAP100; fanconi anemia core complex 100 kDa subunit
D      M00414  Bloom's syndrome complex [PATH:map03460] [BR:ko03400]
E        K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:3.6.4.12]
E        K03165  TOP3; DNA topoisomerase III [EC:5.99.1.2]
E        K10990  RMI1, BRAP75; RecQ-mediated genome instability protein 1
E        K15365  RMI2; RecQ-mediated genome instability protein 2
C    RNA polymerase
D      M00183  RNA polymerase, bacteria [PATH:map03020] [BR:ko03021 ko03400]
E        K03040  rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E        K03043  rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
E        K03046  rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
E        K13797  rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
E        K03060  rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E        K03048  rpoE; DNA-directed RNA polymerase subunit delta
D      M00184  RNA polymerase, archaea [PATH:map03020] [BR:ko03021]
E        K03042  rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
E        K03041  rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
E        K03044  rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
E        K03045  rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
E        K13798  K13798, rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
E        K03053  rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
E        K03055  rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
E        K03058  rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
E        K03047  rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
E        K03049  rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
E        K03050  rpoE2; DNA-directed RNA polymerase subunit E" [EC:2.7.7.6]
E        K03056  rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
E        K03059  rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
E        K03051  rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
E        K03052  rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
E        K03054  rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
D      M00180  RNA polymerase II, eukaryotes [PATH:map03020 map05016] [BR:ko03021 ko03400]
E        K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
E        K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
E        K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
E        K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
E        K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
E        K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
E        K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
E        K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E        K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E        K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E        K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E        K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
D      M00181  RNA polymerase III, eukaryotes [PATH:map03020 map04623] [BR:ko03021]
E        K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
E        K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
E        K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
E        K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
E        K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
E        K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
E        K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
E        K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
E        K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
E        K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
E        K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
E        K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E        K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E        K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E        K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E        K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
D      M00182  RNA polymerase I, eukaryotes [PATH:map03020] [BR:ko03021]
E        K02999  RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
E        K03002  RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
E        K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
E        K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
E        K03000  RPA12, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
E        K03001  RPA14; DNA-directed RNA polymerase I subunit RPA14
E        K03003  RPA34; DNA-directed RNA polymerase I subunit RPA34
E        K03004  RPA43; DNA-directed RNA polymerase I subunit RPA43
E        K03005  RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
E        K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
E        K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
E        K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
E        K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E        K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
C    Spliceosome
D      M00351  Spliceosome, U1-snRNP [PATH:map03040] [BR:ko03041]
E        K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
E        K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
E        K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
E        K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
E        K11097  SNRPE, SME; small nuclear ribonucleoprotein E
E        K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
E        K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
E        K11093  SNRP70; U1 small nuclear ribonucleoprotein 70kDa
E        K11091  SNRPA; U1 small nuclear ribonucleoprotein A
E        K11095  SNRPC; U1 small nuclear ribonucleoprotein C
D      M00352  Spliceosome, U2-snRNP [PATH:map03040] [BR:ko03041]
E        K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
E        K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
E        K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
E        K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
E        K11097  SNRPE, SME; small nuclear ribonucleoprotein E
E        K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
E        K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
E        K11092  SNRPA1; U2 small nuclear ribonucleoprotein A'
E        K11094  SNRPB2; U2 small nuclear ribonucleoprotein B''
E        K12825  SF3A1, SAP114; splicing factor 3A subunit 1
E        K12826  SF3A2, SAP62; splicing factor 3A subunit 2
E        K12827  SF3A3, SAP61, PRP9; splicing factor 3A subunit 3
E        K12828  SF3B1, SAP155; splicing factor 3B subunit 1
E        K12829  SF3B2, SAP145, CUS1; splicing factor 3B subunit 2
E        K12830  SF3B3, SAP130, RSE1; splicing factor 3B subunit 3
E        K12831  SF3B4, SAP49; splicing factor 3B subunit 4
E        K12832  SF3B5, SF3B10; splicing factor 3B subunit 5
E        K12833  SF3B14; pre-mRNA branch site protein p14
E        K12835  DDX42, SF3B125; ATP-dependent RNA helicase DDX42 [EC:3.6.4.13]
E        K12834  PHF5A; PHD finger-like domain-containing protein 5A
D      M00354  Spliceosome, U4/U6.U5 tri-snRNP [PATH:map03040] [BR:ko03041]
E        K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
E        K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
E        K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
E        K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
E        K11097  SNRPE, SME; small nuclear ribonucleoprotein E
E        K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
E        K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
E        K12621  LSM2; U6 snRNA-associated Sm-like protein LSm2
E        K12622  LSM3; U6 snRNA-associated Sm-like protein LSm3
E        K12623  LSM4; U6 snRNA-associated Sm-like protein LSm4
E        K12624  LSM5; U6 snRNA-associated Sm-like protein LSm5
E        K12625  LSM6; U6 snRNA-associated Sm-like protein LSm6
E        K12626  LSM7; U6 snRNA-associated Sm-like protein LSm7
E        K12627  LSM8; U6 snRNA-associated Sm-like protein LSm8
E        K12843  PRPF3, PRP3; U4/U6 small nuclear ribonucleoprotein PRP3
E        K12662  PRPF4, PRP4; U4/U6 small nuclear ribonucleoprotein PRP4
E        K09567  PPIH, CYPH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
E        K12844  PRPF31; U4/U6 small nuclear ribonucleoprotein PRP31
E        K12845  SNU13, NHP2L; U4/U6 small nuclear ribonucleoprotein SNU13
E        K12852  EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component
E        K12853  SNU114; 114 kDa U5 small nuclear ribonucleoprotein component
E        K12855  PRPF6, PRP6; pre-mRNA-processing factor 6
E        K12856  PRPF8, PRP8; pre-mRNA-processing factor 8
E        K12857  SNRNP40, PRP8BP; Prp8 binding protein
E        K12854  SNRNP200, BRR2; pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13]
E        K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]
E        K12859  TXNL4A, DIB1; U5 snRNP protein, DIM1 family
E        K13099  CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2
E        K11984  SART1, HAF, SNU66; U4/U6.U5 tri-snRNP-associated protein 1
E        K12847  USP39, SAD1; U4/U6.U5 tri-snRNP-associated protein 2
E        K12846  SNRNP27; U4/U6.U5 tri-snRNP-associated protein 3
D      M00355  Spliceosome, 35S U5-snRNP [PATH:map03040] [BR:ko03041]
E        K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
E        K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
E        K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
E        K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
E        K11097  SNRPE, SME; small nuclear ribonucleoprotein E
E        K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
E        K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
E        K12856  PRPF8, PRP8; pre-mRNA-processing factor 8
E        K12854  SNRNP200, BRR2; pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13]
E        K12852  EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component
E        K12857  SNRNP40, PRP8BP; Prp8 binding protein
E        K10599  PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:6.3.2.19]
E        K12860  CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
E        K12861  BCAS2; pre-mRNA-splicing factor SPF27
E        K12862  PLRG1, PRL1, PRP46; pleiotropic regulator 1
E        K12863  CWC15; protein CWC15
E        K06063  SNW1, SKIIP, SKIP; SNW domain-containing protein 1
E        K12867  SYF1, XAB2; pre-mRNA-splicing factor SYF1
E        K12868  SYF2; pre-mRNA-splicing factor SYF2
E        K12869  CRN, CRNKL1, CLF1, SYF3; crooked neck
E        K12870  ISY1; pre-mRNA-splicing factor ISY1
E        K12871  CCDC12; coiled-coil domain-containing protein 12
E        K12872  RBM22, SLT11; pre-mRNA-splicing factor RBM22/SLT11
E        K12873  BUD31, G10; bud site selection protein 31
E        K12874  AQR; intron-binding protein aquarius
E        K09564  PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
E        K12733  PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
E        K12816  CDC40, PRP17; pre-mRNA-processing factor 17
E        K13117  DHX35; ATP-dependent RNA helicase DDX35 [EC:3.6.4.13]
E        K03283  HSPA1_8; heat shock 70kDa protein 1/8
E        K13123  GPATCH1; G patch domain-containing protein 1
D      M00353  Spliceosome, Prp19/CDC5L complex [PATH:map03040] [BR:ko03041]
E        K10599  PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:6.3.2.19]
E        K12860  CDC5L, CDC5, CEF1; pre-mRNA-splicing factor CDC5/CEF1
E        K12861  BCAS2; pre-mRNA-splicing factor SPF27
E        K12862  PLRG1, PRL1, PRP46; pleiotropic regulator 1
E        K12863  CWC15; protein CWC15
E        K12864  CTNNBL1; beta-catenin-like protein 1
E        K03283  HSPA1_8; heat shock 70kDa protein 1/8
E        K12865  PQBP1, NPW38; polyglutamine-binding protein 1
E        K12866  WBP11, NPWBP; WW domain-binding protein 11
D      M00396  Lsm 2-8 complex [PATH:map03040 map03018] [BR:ko03041]
E        K12621  LSM2; U6 snRNA-associated Sm-like protein LSm2
E        K12622  LSM3; U6 snRNA-associated Sm-like protein LSm3
E        K12623  LSM4; U6 snRNA-associated Sm-like protein LSm4
E        K12624  LSM5; U6 snRNA-associated Sm-like protein LSm5
E        K12625  LSM6; U6 snRNA-associated Sm-like protein LSm6
E        K12626  LSM7; U6 snRNA-associated Sm-like protein LSm7
E        K12627  LSM8; U6 snRNA-associated Sm-like protein LSm8
D      M00397  Lsm 1-7 complex [PATH:map03018]
E        K12620  LSM1; U6 snRNA-associated Sm-like protein LSm1
E        K12621  LSM2; U6 snRNA-associated Sm-like protein LSm2
E        K12622  LSM3; U6 snRNA-associated Sm-like protein LSm3
E        K12623  LSM4; U6 snRNA-associated Sm-like protein LSm4
E        K12624  LSM5; U6 snRNA-associated Sm-like protein LSm5
E        K12625  LSM6; U6 snRNA-associated Sm-like protein LSm6
E        K12626  LSM7; U6 snRNA-associated Sm-like protein LSm7
D      M00398  Sm core complex [PATH:map03040] [BR:ko03032 ko03041]
E        K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'
E        K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1
E        K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2
E        K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3
E        K11097  SNRPE, SME; small nuclear ribonucleoprotein E
E        K11098  SNRPF, SMF; small nuclear ribonucleoprotein F
E        K11099  SNRPG, SMG; small nuclear ribonucleoprotein G
D      M00399  Cap binding complex [PATH:map03013 map03015 map03040 map03040] [BR:ko03041]
E        K12882  NCBP1, CBP80; nuclear cap-binding protein subunit 1
E        K12883  NCBP2, CBP20; nuclear cap-binding protein subunit 2
C    RNA processing
D      M00425  H/ACA ribonucleoprotein complex [PATH:map03008] [BR:ko03032 ko03009]
E        K11128  GAR1, NOLA1; H/ACA ribonucleoprotein complex subunit 1
E        K11129  NHP2, NOLA2; H/ACA ribonucleoprotein complex subunit 2
E        K11130  NOP10, NOLA3; H/ACA ribonucleoprotein complex subunit 3
E        K11131  DKC1, NOLA4, CBF5; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
D      M00426  Survival motor neuron (SMN) complex [PATH:map03013] [BR:ko03041]
E        K13129  SMN; survival motor neuron protein
E        K13130  SIP1, GEMIN2; survival of motor neuron protein-interacting protein 1
E        K13131  DDX20, GEMIN3; ATP-dependent RNA helicase DDX20 [EC:3.6.4.13]
E        K13132  GEMIN4; gem associated protein 4
E        K13133  GEMIN5; gem associated protein 5
E        K13134  GEMIN6, SIP2; gem associated protein 6
E        K13135  GEMIN7, SIP3; gem associated protein 7
E        K13136  GEMIN8; gem associated protein 8
E        K13137  STRAP, UNRIP; serine-threonine kinase receptor-associated protein
D      M00427  Nuclear pore complex [PATH:map03013]
E        K09291  TPR; nucleoprotein TPR
E        K14295  NUP50, NPAP60; nuclear pore complex protein Nup50
E        K14296  NUP153; nuclear pore complex protein Nup153
E        K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E        K14297  NUP98, ADAR2; nuclear pore complex protein Nup98-Nup96
E        K14298  RAE1; mRNA export factor
E        K14004  SEC13; protein transport protein SEC13
E        K14299  SEH1; nucleoporin SEH1
E        K14300  NUP133; nuclear pore complex protein Nup133
E        K14301  NUP107; nuclear pore complex protein Nup107
E        K14302  NUP37; nuclear pore complex protein Nup37
E        K14303  NUP160; nuclear pore complex protein Nup160
E        K14304  NUP85; nuclear pore complex protein Nup85
E        K14305  NUP43; nuclear pore complex protein Nup43
E        K14306  NUP62; nuclear pore complex protein Nup62
E        K14307  NUPL1; nucleoporin p58/p45
E        K14308  NUP54; nuclear pore complex protein Nup54
E        K14309  NUP93; nuclear pore complex protein Nup93
E        K14310  NUP205; nuclear pore complex protein Nup205
E        K14311  NUP188; nuclear pore complex protein Nup188
E        K14312  NUP155; nuclear pore complex protein Nup155
E        K14313  NUP35, NUP53; nuclear pore complex protein Nup53
E        K14314  NUP210, GP210; nuclear pore complex protein Nup210
E        K14315  NDC1, TMEM48; nucleoporin NDC1
E        K14316  POM121, NUP121; nuclear pore complex protein Nup121
E        K14317  NUP214, CAN; nuclear pore complex protein Nup214
E        K14318  NUP88; nuclear pore complex protein Nup88
E        K12172  RANBP2, NUP358; E3 SUMO-protein ligase RanBP2
E        K14319  RANGAP1; Ran GTPase-activating protein 1
E        K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
E        K12160  SUMO, SMT3; small ubiquitin-related modifier
E        K14320  AAAS; aladin
E        K14321  NUPL2, CG1; nucleoporin-like protein 2
D      M00428  eIF4F complex [PATH:map03013] [BR:ko03012]
E        K03259  EIF4E; translation initiation factor 4E
E        K03260  EIF4G; translation initiation factor 4G
E        K03257  EIF4A; translation initiation factor 4A
D      M00430  Exon junction complex (EJC) [PATH:map03013 map03015 map03040] [BR:ko03041]
E        K12876  RBM8A, Y14; RNA-binding protein 8A
E        K12877  MAGOH; protein mago nashi
E        K14323  CASC3, MLN51; protein CASC3
E        K13025  EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
E        K14324  SAP18; histone deacetylase complex subunit SAP18
E        K13114  PNN; pinin
E        K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
E        K14325  RNPS1; RNA-binding protein with serine-rich domain 1
E        K12881  THOC4, ALY; THO complex subunit 4
E        K12812  UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
E        K13171  SRRM1, SRM160; serine/arginine repetitive matrix protein 1
E        K14285  NXT1_2, P15; NTF2-related export protein 1/2
E        K14326  UPF1, RENT1; regulator of nonsense transcripts 1 [EC:3.6.4.-]
E        K14327  UPF2, RENT2; regulator of nonsense transcripts 2
E        K14328  UPF3, RENT3; regulator of nonsense transcripts 3
D      M00405  THC complex [PATH:map03040 map03013] [BR:ko03041]
E        K12878  THOC1; THO complex subunit 1
E        K12879  THOC2; THO complex subunit 2
E        K13174  THOC5; THO complex subunit 5
E        K13175  THOC6; THO complex subunit 6
E        K13176  THOC7; THO complex subunit 7
D      M00406  TREX complex [PATH:map03013 map03040] [BR:ko03041]
E        K12878  THOC1; THO complex subunit 1
E        K12879  THOC2; THO complex subunit 2
E        K13174  THOC5; THO complex subunit 5
E        K13175  THOC6; THO complex subunit 6
E        K13176  THOC7; THO complex subunit 7
E        K12880  THOC3; THO complex subunit 3
E        K12881  THOC4, ALY; THO complex subunit 4
E        K12812  UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
D      M00390  Exosome, archaea [PATH:map03018]
E        K07573  CSL4, EXOSC1; exosome complex component CSL4
E        K03679  RRP4, EXOSC2; exosome complex component RRP4
E        K11600  RRP41, EXOSC4, SKI6; exosome complex component RRP41
E        K12589  RRP42, EXOSC7; exosome complex component RRP42
D      M00391  Exosome, eukaryotes [PATH:map03018]
E        K07573  CSL4, EXOSC1; exosome complex component CSL4
E        K12587  MTR3, EXOSC6; exosome complex component MTR3
E        K03679  RRP4, EXOSC2; exosome complex component RRP4
E        K03681  RRP40, EXOSC3; exosome complex component RRP40
E        K11600  RRP41, EXOSC4, SKI6; exosome complex component RRP41
E        K12589  RRP42, EXOSC7; exosome complex component RRP42
E        K12586  RRP43, EXOSC8, OIP2; exosome complex component RRP43
E        K12585  DIS3, RRP44; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E        K03678  RRP45, EXOSC9; exosome complex component RRP45
E        K12590  RRP46, EXOSC5; exosome complex component RRP46
D      M00392  Ski complex [PATH:map03018]
E        K12599  SKI2, SKIV2L; antiviral helicase SKI2 [EC:3.6.4.-]
E        K12600  SKI3, TTC37; superkiller protein 3
E        K12601  SKI8; superkiller protein 8
E        K12602  WDR61, REC14, SKI8; WD repeat-containing protein 61
D      M00393  TRAMP complex [PATH:map03018]
E        K03514  POLS, TRF4; DNA polymerase sigma [EC:2.7.7.7]
E        K12596  TRF5; poly(A) RNA polymerase
E        K12597  AIR1_2; protein AIR1/2
E        K12598  MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:3.6.4.13]
D      M00394  RNA degradosome [PATH:map03018]
E        K08300  rne; ribonuclease E [EC:3.1.26.12]
E        K03732  rhlB; ATP-dependent RNA helicase RhlB [EC:3.6.4.13]
E        K01689  ENO, eno; enolase [EC:4.2.1.11]
E        K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D      M00395  Decapping complex [PATH:map03018]
E        K12610  DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E        K12611  DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E        K12612  DCP1; mRNA-decapping enzyme subunit 1
E        K12613  DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E        K12614  DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
E        K12615  EDC3; enhancer of mRNA-decapping protein 3
E        K12617  PATL1, PAT1; DNA topoisomerase 2-associated protein PAT1
C    Ribosome
D      M00178  Ribosome, bacteria [PATH:map03010] [BR:ko03011]
E        K02945  RP-S1, rpsA; small subunit ribosomal protein S1
E        K02967  RP-S2, rpsB; small subunit ribosomal protein S2
E        K02982  RP-S3, rpsC; small subunit ribosomal protein S3
E        K02986  RP-S4, rpsD; small subunit ribosomal protein S4
E        K02988  RP-S5, rpsE; small subunit ribosomal protein S5
E        K02990  RP-S6, rpsF; small subunit ribosomal protein S6
E        K02992  RP-S7, rpsG; small subunit ribosomal protein S7
E        K02994  RP-S8, rpsH; small subunit ribosomal protein S8
E        K02996  RP-S9, rpsI; small subunit ribosomal protein S9
E        K02946  RP-S10, rpsJ; small subunit ribosomal protein S10
E        K02948  RP-S11, rpsK; small subunit ribosomal protein S11
E        K02950  RP-S12, rpsL; small subunit ribosomal protein S12
E        K02952  RP-S13, rpsM; small subunit ribosomal protein S13
E        K02954  RP-S14, rpsN; small subunit ribosomal protein S14
E        K02956  RP-S15, rpsO; small subunit ribosomal protein S15
E        K02959  RP-S16, rpsP; small subunit ribosomal protein S16
E        K02961  RP-S17, rpsQ; small subunit ribosomal protein S17
E        K02963  RP-S18, rpsR; small subunit ribosomal protein S18
E        K02965  RP-S19, rpsS; small subunit ribosomal protein S19
E        K02968  RP-S20, rpsT; small subunit ribosomal protein S20
E        K02970  RP-S21, rpsU; small subunit ribosomal protein S21
E        K02863  RP-L1, rplA; large subunit ribosomal protein L1
E        K02886  RP-L2, rplB; large subunit ribosomal protein L2
E        K02906  RP-L3, rplC; large subunit ribosomal protein L3
E        K02926  RP-L4, rplD; large subunit ribosomal protein L4
E        K02931  RP-L5, rplE; large subunit ribosomal protein L5
E        K02933  RP-L6, rplF; large subunit ribosomal protein L6
E        K02935  RP-L7, rplL; large subunit ribosomal protein L7/L12
E        K02939  RP-L9, rplI; large subunit ribosomal protein L9
E        K02864  RP-L10, rplJ; large subunit ribosomal protein L10
E        K02867  RP-L11, rplK; large subunit ribosomal protein L11
E        K02871  RP-L13, rplM; large subunit ribosomal protein L13
E        K02874  RP-L14, rplN; large subunit ribosomal protein L14
E        K02876  RP-L15, rplO; large subunit ribosomal protein L15
E        K02878  RP-L16, rplP; large subunit ribosomal protein L16
E        K02879  RP-L17, rplQ; large subunit ribosomal protein L17
E        K02881  RP-L18, rplR; large subunit ribosomal protein L18
E        K02884  RP-L19, rplS; large subunit ribosomal protein L19
E        K02887  RP-L20, rplT; large subunit ribosomal protein L20
E        K02888  RP-L21, rplU; large subunit ribosomal protein L21
E        K02890  RP-L22, rplV; large subunit ribosomal protein L22
E        K02892  RP-L23, rplW; large subunit ribosomal protein L23
E        K02895  RP-L24, rplX; large subunit ribosomal protein L24
E        K02897  RP-L25, rplY; large subunit ribosomal protein L25
E        K02899  RP-L27, rpmA; large subunit ribosomal protein L27
E        K02902  RP-L28, rpmB; large subunit ribosomal protein L28
E        K02904  RP-L29, rpmC; large subunit ribosomal protein L29
E        K02907  RP-L30, rpmD; large subunit ribosomal protein L30
E        K02909  RP-L31, rpmE; large subunit ribosomal protein L31
E        K02911  RP-L32, rpmF; large subunit ribosomal protein L32
E        K02913  RP-L33, rpmG; large subunit ribosomal protein L33
E        K02914  RP-L34, rpmH; large subunit ribosomal protein L34
E        K02916  RP-L35, rpmI; large subunit ribosomal protein L35
E        K02919  RP-L36, rpmJ; large subunit ribosomal protein L36
E        K07590  RP-L7A; large subunit ribosomal protein L7A
D      M00179  Ribosome, archaea [PATH:map03010] [BR:ko03011]
E        K02967  RP-S2, rpsB; small subunit ribosomal protein S2
E        K02982  RP-S3, rpsC; small subunit ribosomal protein S3
E        K02986  RP-S4, rpsD; small subunit ribosomal protein S4
E        K02988  RP-S5, rpsE; small subunit ribosomal protein S5
E        K02992  RP-S7, rpsG; small subunit ribosomal protein S7
E        K02994  RP-S8, rpsH; small subunit ribosomal protein S8
E        K02996  RP-S9, rpsI; small subunit ribosomal protein S9
E        K02946  RP-S10, rpsJ; small subunit ribosomal protein S10
E        K02948  RP-S11, rpsK; small subunit ribosomal protein S11
E        K02950  RP-S12, rpsL; small subunit ribosomal protein S12
E        K02952  RP-S13, rpsM; small subunit ribosomal protein S13
E        K02954  RP-S14, rpsN; small subunit ribosomal protein S14
E        K02956  RP-S15, rpsO; small subunit ribosomal protein S15
E        K02961  RP-S17, rpsQ; small subunit ribosomal protein S17
E        K02965  RP-S19, rpsS; small subunit ribosomal protein S19
E        K02984  RP-S3Ae, RPS3A; small subunit ribosomal protein S3Ae
E        K02987  RP-S4e, RPS4; small subunit ribosomal protein S4e
E        K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
E        K02995  RP-S8e, RPS8; small subunit ribosomal protein S8e
E        K02962  RP-S17e, RPS17; small subunit ribosomal protein S17e
E        K02966  RP-S19e, RPS19; small subunit ribosomal protein S19e
E        K02974  RP-S24e, RPS24; small subunit ribosomal protein S24e
E        K02975  RP-S25e, RPS25; small subunit ribosomal protein S25e
E        K02976  RP-S26e, RPS26; small subunit ribosomal protein S26e
E        K02978  RP-S27e, RPS27; small subunit ribosomal protein S27e
E        K02977  RP-S27Ae, RPS27A; small subunit ribosomal protein S27Ae
E        K02979  RP-S28e, RPS28; small subunit ribosomal protein S28e
E        K02983  RP-S30e, RPS30; small subunit ribosomal protein S30e
E        K02863  RP-L1, rplA; large subunit ribosomal protein L1
E        K02886  RP-L2, rplB; large subunit ribosomal protein L2
E        K02906  RP-L3, rplC; large subunit ribosomal protein L3
E        K02931  RP-L5, rplE; large subunit ribosomal protein L5
E        K02933  RP-L6, rplF; large subunit ribosomal protein L6
E        K02864  RP-L10, rplJ; large subunit ribosomal protein L10
E        K02867  RP-L11, rplK; large subunit ribosomal protein L11
E        K02869  RP-L12, rpl12; large subunit ribosomal protein L12
E        K02871  RP-L13, rplM; large subunit ribosomal protein L13
E        K02874  RP-L14, rplN; large subunit ribosomal protein L14
E        K02876  RP-L15, rplO; large subunit ribosomal protein L15
E        K02881  RP-L18, rplR; large subunit ribosomal protein L18
E        K02890  RP-L22, rplV; large subunit ribosomal protein L22
E        K02892  RP-L23, rplW; large subunit ribosomal protein L23
E        K02895  RP-L24, rplX; large subunit ribosomal protein L24
E        K02904  RP-L29, rpmC; large subunit ribosomal protein L29
E        K02907  RP-L30, rpmD; large subunit ribosomal protein L30
E        K02930  RP-L4e, RPL4; large subunit ribosomal protein L4e
E        K02936  RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae
E        K02866  RP-L10e, RPL10; large subunit ribosomal protein L10e
E        K02873  RP-L13e, RPL13; large subunit ribosomal protein L13e
E        K02875  RP-L14e, RPL14; large subunit ribosomal protein L14e
E        K02877  RP-L15e, RPL15; large subunit ribosomal protein L15e
E        K02883  RP-L18e, RPL18; large subunit ribosomal protein L18e
E        K02885  RP-L19e, RPL19; large subunit ribosomal protein L19e
E        K02889  RP-L21e, RPL21; large subunit ribosomal protein L21e
E        K02896  RP-L24e, RPL24; large subunit ribosomal protein L24e
E        K02908  RP-L30e, RPL30; large subunit ribosomal protein L30e
E        K02910  RP-L31e, RPL31; large subunit ribosomal protein L31e
E        K02912  RP-L32e, RPL32; large subunit ribosomal protein L32e
E        K02915  RP-L34e, RPL34; large subunit ribosomal protein L34e
E        K02917  RP-L35Ae, RPL35A; large subunit ribosomal protein L35Ae
E        K02922  RP-L37e, RPL37; large subunit ribosomal protein L37e
E        K02921  RP-L37Ae, RPL37A; large subunit ribosomal protein L37Ae
E        K02924  RP-L39e, RPL39; large subunit ribosomal protein L39e
E        K02927  RP-L40e, RPL40; large subunit ribosomal protein L40e
E        K02928  RP-L41e, RPL41; large subunit ribosomal protein L41e
E        K02929  RP-L44e, RPL44; large subunit ribosomal protein L44e
E        K02944  RP-LX, rplX; large subunit ribosomal protein LX
D      M00177  Ribosome, eukaryotes [PATH:map03010] [BR:ko03011]
E        K02981  RP-S2e, RPS2; small subunit ribosomal protein S2e
E        K02985  RP-S3e, RPS3; small subunit ribosomal protein S3e
E        K02984  RP-S3Ae, RPS3A; small subunit ribosomal protein S3Ae
E        K02987  RP-S4e, RPS4; small subunit ribosomal protein S4e
E        K02989  RP-S5e, RPS5; small subunit ribosomal protein S5e
E        K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
E        K02993  RP-S7e, RPS7; small subunit ribosomal protein S7e
E        K02995  RP-S8e, RPS8; small subunit ribosomal protein S8e
E        K02997  RP-S9e, RPS9; small subunit ribosomal protein S9e
E        K02947  RP-S10e, RPS10; small subunit ribosomal protein S10e
E        K02949  RP-S11e, RPS11; small subunit ribosomal protein S11e
E        K02951  RP-S12e, RPS12; small subunit ribosomal protein S12e
E        K02953  RP-S13e, RPS13; small subunit ribosomal protein S13e
E        K02955  RP-S14e, RPS14; small subunit ribosomal protein S14e
E        K02958  RP-S15e, RPS15; small subunit ribosomal protein S15e
E        K02957  RP-S15Ae, RPS15A; small subunit ribosomal protein S15Ae
E        K02960  RP-S16e, RPS16; small subunit ribosomal protein S16e
E        K02962  RP-S17e, RPS17; small subunit ribosomal protein S17e
E        K02964  RP-S18e, RPS18; small subunit ribosomal protein S18e
E        K02966  RP-S19e, RPS19; small subunit ribosomal protein S19e
E        K02969  RP-S20e, RPS20; small subunit ribosomal protein S20e
E        K02971  RP-S21e, RPS21; small subunit ribosomal protein S21e
E        K02973  RP-S23e, RPS23; small subunit ribosomal protein S23e
E        K02974  RP-S24e, RPS24; small subunit ribosomal protein S24e
E        K02975  RP-S25e, RPS25; small subunit ribosomal protein S25e
E        K02976  RP-S26e, RPS26; small subunit ribosomal protein S26e
E        K02978  RP-S27e, RPS27; small subunit ribosomal protein S27e
E        K02977  RP-S27Ae, RPS27A; small subunit ribosomal protein S27Ae
E        K02979  RP-S28e, RPS28; small subunit ribosomal protein S28e
E        K02980  RP-S29e, RPS29; small subunit ribosomal protein S29e
E        K02983  RP-S30e, RPS30; small subunit ribosomal protein S30e
E        K02998  RP-SAe, RPS0; small subunit ribosomal protein SAe
E        K02925  RP-L3e, RPL3; large subunit ribosomal protein L3e
E        K02930  RP-L4e, RPL4; large subunit ribosomal protein L4e
E        K02932  RP-L5e, RPL5; large subunit ribosomal protein L5e
E        K02934  RP-L6e, RPL6; large subunit ribosomal protein L6e
E        K02937  RP-L7e, RPL7; large subunit ribosomal protein L7e
E        K02936  RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae
E        K02938  RP-L8e, RPL8; large subunit ribosomal protein L8e
E        K02940  RP-L9e, RPL9; large subunit ribosomal protein L9e
E        K02866  RP-L10e, RPL10; large subunit ribosomal protein L10e
E        K02865  RP-L10Ae, RPL10A; large subunit ribosomal protein L10Ae
E        K02868  RP-L11e, RPL11; large subunit ribosomal protein L11e
E        K02870  RP-L12e, RPL12; large subunit ribosomal protein L12e
E        K02873  RP-L13e, RPL13; large subunit ribosomal protein L13e
E        K02872  RP-L13Ae, RPL13A; large subunit ribosomal protein L13Ae
E        K02875  RP-L14e, RPL14; large subunit ribosomal protein L14e
E        K02877  RP-L15e, RPL15; large subunit ribosomal protein L15e
E        K02880  RP-L17e, RPL17; large subunit ribosomal protein L17e
E        K02883  RP-L18e, RPL18; large subunit ribosomal protein L18e
E        K02882  RP-L18Ae, RPL18A; large subunit ribosomal protein L18Ae
E        K02885  RP-L19e, RPL19; large subunit ribosomal protein L19e
E        K02889  RP-L21e, RPL21; large subunit ribosomal protein L21e
E        K02891  RP-L22e, RPL22; large subunit ribosomal protein L22e
E        K02894  RP-L23e, RPL23; large subunit ribosomal protein L23e
E        K02893  RP-L23Ae, RPL23A; large subunit ribosomal protein L23Ae
E        K02896  RP-L24e, RPL24; large subunit ribosomal protein L24e
E        K02898  RP-L26e, RPL26; large subunit ribosomal protein L26e
E        K02901  RP-L27e, RPL27; large subunit ribosomal protein L27e
E        K02900  RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae
E        K02903  RP-L28e, RPL28; large subunit ribosomal protein L28e
E        K02905  RP-L29e, RPL29; large subunit ribosomal protein L29e
E        K02908  RP-L30e, RPL30; large subunit ribosomal protein L30e
E        K02910  RP-L31e, RPL31; large subunit ribosomal protein L31e
E        K02912  RP-L32e, RPL32; large subunit ribosomal protein L32e
E        K02915  RP-L34e, RPL34; large subunit ribosomal protein L34e
E        K02918  RP-L35e, RPL35; large subunit ribosomal protein L35e
E        K02917  RP-L35Ae, RPL35A; large subunit ribosomal protein L35Ae
E        K02920  RP-L36e, RPL36; large subunit ribosomal protein L36e
E        K02922  RP-L37e, RPL37; large subunit ribosomal protein L37e
E        K02921  RP-L37Ae, RPL37A; large subunit ribosomal protein L37Ae
E        K02923  RP-L38e, RPL38; large subunit ribosomal protein L38e
E        K02924  RP-L39e, RPL39; large subunit ribosomal protein L39e
E        K02927  RP-L40e, RPL40; large subunit ribosomal protein L40e
E        K02928  RP-L41e, RPL41; large subunit ribosomal protein L41e
E        K02929  RP-L44e, RPL44; large subunit ribosomal protein L44e
E        K02941  RP-LP0, RPLP0; large subunit ribosomal protein LP0
E        K02942  RP-LP1, RPLP1; large subunit ribosomal protein LP1
E        K02943  RP-LP2, RPLP2; large subunit ribosomal protein LP2
C    Proteasome
D      M00340  Proteasome, 20S core particle [PATH:map03050] [BR:ko03051]
E        K02725  PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
E        K02726  PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
E        K02727  PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
E        K02728  PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
E        K02729  PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
E        K02730  PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
E        K02731  PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
E        K02732  PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
E        K02734  PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
E        K02735  PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
E        K02736  PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
E        K02737  PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
E        K02738  PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
E        K02739  PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
D      M00341  Proteasome, 19S regulatory particle (PA700) [PATH:map03050] [BR:ko03051]
E        K03061  PSMC2, RPT1; 26S proteasome regulatory subunit T1
E        K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2
E        K03063  PSMC4, RPT3; 26S proteasome regulatory subunit T3
E        K03064  PSMC6, RPT4; 26S proteasome regulatory subunit T4
E        K03065  PSMC3, RPT5; 26S proteasome regulatory subunit T5
E        K03066  PSMC5, RPT6; 26S proteasome regulatory subunit T6
E        K03028  PSMD2, RPN1; 26S proteasome regulatory subunit N1
E        K03032  PSMD1, RPN2; 26S proteasome regulatory subunit N2
E        K03033  PSMD3, RPN3; 26S proteasome regulatory subunit N3
E        K03035  PSMD12, RPN5; 26S proteasome regulatory subunit N5
E        K03036  PSMD11, RPN6; 26S proteasome regulatory subunit N6
E        K03037  PSMD6, RPN7; 26S proteasome regulatory subunit N7
E        K03038  PSMD7, RPN8; 26S proteasome regulatory subunit N8
E        K03039  PSMD13, RPN9; 26S proteasome regulatory subunit N9
E        K03029  PSMD4, RPN10; 26S proteasome regulatory subunit N10
E        K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
E        K03031  PSMD8, RPN12; 26S proteasome regulatory subunit N12
E        K06691  RPN13; 26S proteasome regulatory subunit N13
E        K10881  SHFM1, DSS1; 26 proteasome complex subunit DSS1
D      M00337  Immunoproteasome [PATH:map03050] [BR:ko03051]
E        K02725  PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
E        K02726  PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
E        K02727  PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
E        K02728  PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
E        K02729  PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
E        K02730  PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
E        K02731  PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
E        K02732  PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
E        K02734  PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
E        K02735  PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
E        K02736  PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
E        K02741  PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]
E        K02733  PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]
E        K02740  PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]
E        K06696  PSME1; proteasome activator subunit 1 (PA28 alpha)
E        K06697  PSME2; proteasome activator subunit 2 (PA28 beta)
D      M00342  Bacterial proteasome [PATH:map03050] [BR:ko03051]
E        K03432  psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
E        K03433  psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
E        K13527  mpa; proteasome-associated ATPase
E        K13571  pafA; proteasome accessory factor A [EC:6.3.2.-]
D      M00343  Archaeal proteasome [PATH:map03050] [BR:ko03051]
E        K03432  psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
E        K03433  psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
E        K03420  psmR; proteasome regulatory subunit
C    Ubiquitin system
D      M00379  SCF-MET30 complex [PATH:map04120 map04111] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K10259  MET30; F-box and WD-40 domain protein MET30
D      M00380  SCF-BTRC complex [PATH:map04120 map04114 map04310 map04710] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
D      M00381  SCF-SKP2 complex [PATH:map04120 map04110 map05168] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
D      M00382  SCF-FBS complex [PATH:map04120 map04141] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K10099  FBXO2, NFB42; F-box protein 2
E        K10100  FBXO6; F-box protein 6
D      M00407  SCF-CDC4 complex [PATH:map04120 map04111] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K03361  CDC4; F-box and WD-40 domain protein CDC4
D      M00411  SCF-GRR1 complex [PATH:map04120 map04111] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K03360  GRR1; F-box and leucine-rich repeat protein GRR1
D      M00383  ECV complex [PATH:map04120 map05211] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03870  CUL2; cullin 2
E        K03872  TCEB1; transcription elongation factor B, polypeptide 1
E        K03873  TCEB2; transcription elongation factor B, polypeptide 2
E        K03871  VHL; von Hippel-Lindau disease tumor supressor
D      M00384  Cul3-SPOP complex [PATH:map04120] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03869  CUL3; cullin 3
E        K10523  SPOP; speckle-type POZ protein
D      M00385  Cul4-DDB1-DDB2 complex [PATH:map04120 map03420] [BR:ko04121 ko03400]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K10609  CUL4; cullin 4
E        K10610  DDB1; DNA damage-binding protein 1
E        K10140  DDB2; DNA damage-binding protein 2
D      M00386  Cul4-DDB1-CSA complex [PATH:map04120 map03420] [BR:ko04121 ko03400]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K10609  CUL4; cullin 4
E        K10610  DDB1; DNA damage-binding protein 1
E        K10570  ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
D      M00387  SCF-FBW7 complex [PATH:map04120] [BR:ko04121]
E        K03868  RBX1, ROC1; RING-box protein 1
E        K03347  CUL1, CDC53; cullin 1
E        K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
E        K10260  FBXW7, SEL10; F-box and WD-40 domain protein 7
D      M00388  ECS complex [PATH:map04120] [BR:ko04121]
E        K10611  RBX2, ROC2, RNF7; RING-box protein 2
E        K10612  CUL5; cullin 5
E        K03872  TCEB1; transcription elongation factor B, polypeptide 1
E        K03873  TCEB2; transcription elongation factor B, polypeptide 2
E        K04701  CISH; cytokine inducible SH2-containing protein
E        K04694  SOCS1, JAB; suppressor of cytokine signaling 1
E        K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
E        K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
E        K04697  SOCS4; suppressor of cytokine signaling 4
E        K04698  SOCS5; suppressor of cytokine signaling 5
E        K10322  SOCS6, CIS4; suppressor of cytokine signaling 6
E        K04699  SOCS7, NAP4; suppressor of cytokine signaling 7
D      M00389  APC/C complex [PATH:map04120 map04110 map04114 map04914 map04111 map04113] [BR:ko04121 ko03036]
E        K03358  APC11; anaphase-promoting complex subunit 11
E        K03349  APC2; anaphase-promoting complex subunit 2
E        K03363  CDC20; cell division cycle 20, cofactor of APC complex
E        K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E        K03348  APC1; anaphase-promoting complex subunit 1
E        K03350  APC3, CDC27; anaphase-promoting complex subunit 3
E        K03351  APC4; anaphase-promoting complex subunit 4
E        K03352  APC5; anaphase-promoting complex subunit 5
E        K03353  APC6, CDC16; anaphase-promoting complex subunit 6
E        K03354  APC7; anaphase-promoting complex subunit 7
E        K03356  APC9; anaphase-promoting complex subunit 9
E        K03355  APC8, CDC23; anaphase-promoting complex subunit 8
E        K03357  APC10, DOC1; anaphase-promoting complex subunit 10
E        K03359  APC12, CDC26; anaphase-promoting complex subunit 12
E        K12456  APC13; anaphase-promoting complex subunit 13
C    Protein processing
D      M00400  p97-Ufd1-Npl4 complex [PATH:map04141]
E        K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
E        K14016  UFD1; ubiquitin fusion degradation protein 1
E        K14015  NPLOC4, NPL4; nuclear protein localization protein 4 homolog
D      M00401  Sec61 complex [PATH:map03060 map04141 map04145 map05110] [BR:ko02044]
E        K10956  SEC61A; protein transport protein SEC61 subunit alpha
E        K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
E        K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
D      M00402  Translocon-associated protein (TRAP) complex [PATH:map04141]
E        K13249  SSR1; translocon-associated protein subunit alpha
E        K13250  SSR2; translocon-associated protein subunit beta
E        K13251  SSR3; translocon-associated protein subunit gamma
E        K04571  SSR4; translocon-associated protein subunit delta
D      M00403  HRD1/SEL1 ERAD complex [PATH:map04141]
E        K10601  SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19]
E        K14026  SEL1, SEL1L; SEL1 protein
E        K10088  OS9; protein OS-9
E        K14008  ERLEC1, XTP3B; endoplasmic reticulum lectin 1
E        K14027  HERPUD1, HERP; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
E        K11519  DERL1; Derlin-1
E        K13989  DERL2_3; Derlin-2/3
E        K14025  SELS, VIMP; selenoprotein S
E        K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
E        K14015  NPLOC4, NPL4; nuclear protein localization protein 4 homolog
E        K14016  UFD1; ubiquitin fusion degradation protein 1
D      M00404  COPII complex [PATH:map04141]
E        K14004  SEC13; protein transport protein SEC13
E        K14005  SEC31; protein transport protein SEC31
E        K14006  SEC23; protein transport protein SEC23
E        K14007  SEC24; protein transport protein SEC24
E        K07953  SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D      M00408  ESCRT-0 complex [PATH:map04144]
E        K12182  HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
E        K04705  STAM; signal transducing adaptor molecule
D      M00409  ESCRT-I complex [PATH:map04144]
E        K12183  TSG101, STP22, VPS23; ESCRT-I complex subunit TSG101
E        K12184  VPS28; ESCRT-I complex subunit VPS28
E        K12185  VPS37; ESCRT-I complex subunit VPS37
E        K12186  FAM125; ESCRT-I complex subunit MVB12
D      M00410  ESCRT-II complex [PATH:map04144]
E        K12188  SNF8, EAP30; ESCRT-II complex subunit VPS22
E        K12189  VPS25, EAP20; ESCRT-II complex subunit VPS25
E        K12190  VPS36, EAP45; ESCRT-II complex subunit VPS36
D      M00412  ESCRT-III complex [PATH:map04144]
E        K12191  CHMP2A; charged multivesicular body protein 2A
E        K12192  CHMP2B; charged multivesicular body protein 2B
E        K12193  VPS24, CHMP3; charged multivesicular body protein 3
E        K12194  CHMP4, SNF7, VPS32; charged multivesicular body protein 4
E        K12195  CHMP6, VPS20; charged multivesicular body protein 6
E        K12196  VPS4; vacuolar protein-sorting-associated protein 4
E        K12197  CHMP1, VPS46, DID2; charged multivesicular body protein 1
E        K12198  CHMP5, VPS60; charged multivesicular body protein 5
E        K15053  CHMP7; charged multivesicular body protein 7
B
B  <b>Environmental information processing</b>
C    Mineral and organic ion transport system
D      M00185  Sulfate transport system [PATH:map02010] [BR:ko02000]
E        K02048  cysP, sbp; sulfate transport system substrate-binding protein
E        K02046  cysU; sulfate transport system permease protein
E        K02047  cysW; sulfate transport system permease protein
E        K02045  cysA; sulfate transport system ATP-binding protein [EC:3.6.3.25]
D      M00189  Molybdate transport system [PATH:map02010] [BR:ko02000]
E        K02020  modA; molybdate transport system substrate-binding protein
E        K02018  modB; molybdate transport system permease protein
E        K02017  modC; molybdate transport system ATP-binding protein [EC:3.6.3.29]
E        K05776  modF; molybdate transport system ATP-binding protein
D      M00423  Molybdate/tungstate transport system [PATH:map02010] [BR:ko02000]
E        K15495  wtpA; molybdate/tungstate transport system substrate-binding protein
E        K15496  wtpB; molybdate/tungstate transport system permease protein
E        K15497  wtpC; molybdate/tungstate transport system ATP-binding protein [EC:3.6.3.-]
D      M00186  Tungstate transport system [PATH:map02010] [BR:ko02000]
E        K05772  tupA, vupA; tungstate transport system substrate-binding protein
E        K05773  tupB, vupB; tungstate transport system permease protein
E        K06857  tupC, vupC; tungstate transport system ATP-binding protein
D      M00438  Nitrate/nitrite transport system [PATH:map02010] [BR:ko02000]
E        K15576  nrtA, nasF, cynA; nitrate/nitrite transport system substrate-binding protein
E        K15577  nrtB, nasE, cynB; nitrate/nitrite transport system permease protein
E        K15578  nrtC, nasD; nitrate/nitrite transport system ATP-binding protein [EC:3.6.3.-]
E        K15579  nrtD, cynD; nitrate/nitrite transport system ATP-binding protein
D      M00321  Bicarbonate transport system [PATH:map02010] [BR:ko02000]
E        K11950  cmpA; bicarbonate transport system substrate-binding protein
E        K11951  cmpB; bicarbonate transport system permease protein
E        K11952  cmpC; bicarbonate transport system ATP-binding protein [EC:3.6.3.-]
E        K11953  cmpD; bicarbonate transport system ATP-binding protein [EC:3.6.3.-]
D      M00188  NitT/TauT family transport system [BR:ko02000]
E        K02051  ABC.SN.S; NitT/TauT family transport system substrate-binding protein
E        K02050  ABC.SN.P; NitT/TauT family transport system permease protein
E        K02049  ABC.SN.A; NitT/TauT family transport system ATP-binding protein
D      M00435  Taurine transport system [PATH:map02010] [BR:ko02000]
E        K15551  tauA; taurine transport system substrate-binding protein
E        K15552  tauC; taurine transport system permease protein
E        K10831  tauB; taurine transport system ATP-binding protein [EC:3.6.3.36]
D      M00436  Sulfonate transport system [PATH:map02010] [BR:ko02000]
E        K15553  ssuA; sulfonate transport system substrate-binding protein
E        K15554  ssuC; sulfonate transport system permease protein
E        K15555  ssuB; sulfonate transport system ATP-binding protein [EC:3.6.3.-]
D      M00437  Phthalate transport system [PATH:map02010] [BR:ko02000]
E        K15556  ophF; phthalate transport system substrate-binding protein
E        K15557  ophG; phthalate transport system permease protein
E        K15558  ophH; phthalate transport system ATP-binding protein
D      M00190  Iron(III) transport system [PATH:map02010] [BR:ko02000]
E        K02012  afuA, fbpA; iron(III) transport system substrate-binding protein
E        K02011  afuB, fbpB; iron(III) transport system permease protein
E        K02010  afuC, fbpC; iron(III) transport system ATP-binding protein [EC:3.6.3.30]
D      M00191  Thiamine transport system [PATH:map02010] [BR:ko02000]
E        K02064  thiB, tbpA; thiamine transport system substrate-binding protein
E        K02063  thiP; thiamine transport system permease protein
E        K02062  thiQ; thiamine transport system ATP-binding protein
D      M00299  Spermidine/putrescine transport system [PATH:map02010] [BR:ko02000]
E        K11069  potD; spermidine/putrescine transport system substrate-binding protein
E        K11070  potC; spermidine/putrescine transport system permease protein
E        K11071  potB; spermidine/putrescine transport system permease protein
E        K11072  potA; spermidine/putrescine transport system ATP-binding protein [EC:3.6.3.31]
D      M00300  Putrescine transport system [PATH:map02010] [BR:ko02000]
E        K11073  potF; putrescine transport system substrate-binding protein
E        K11074  potI; putrescine transport system permease protein
E        K11075  potH; putrescine transport system permease protein
E        K11076  potG; putrescine transport system ATP-binding protein
D      M00193  Putative spermidine/putrescine transport system [BR:ko02000]
E        K02055  ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
E        K02053  ABC.SP.P; putative spermidine/putrescine transport system permease protein
E        K02054  ABC.SP.P1; putative spermidine/putrescine transport system permease protein
E        K02052  ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D      M00301  Mannopine transport system [PATH:map02010] [BR:ko02000]
E        K11077  attC; mannopine transport system substrate-binding protein
E        K11078  attB; mannopine transport system permease protein
E        K11079  attA2; mannopine transport system permease protein
E        K11080  attA1; mannopine transport system ATP-binding protein
D      M00302  2-Aminoethylphosphonate transport system [PATH:map02010] [BR:ko02000]
E        K11081  phnS; 2-aminoethylphosphonate transport system substrate-binding protein
E        K11082  phnV; 2-aminoethylphosphonate transport system permease protein
E        K11083  phnU; 2-aminoethylphosphonate transport system permease protein
E        K11084  phnT; 2-aminoethylphosphonate transport system ATP-binding protein
D      M00208  Glycine betaine/proline transport system [PATH:map02010] [BR:ko02000]
E        K02002  proX; glycine betaine/proline transport system substrate-binding protein
E        K02001  proW; glycine betaine/proline transport system permease protein
E        K02000  proV; glycine betaine/proline transport system ATP-binding protein [EC:3.6.3.32]
D      M00209  Osmoprotectant transport system [PATH:map02010] [BR:ko02000]
E        K05845  opuC; osmoprotectant transport system substrate-binding protein
E        K05846  opuBD; osmoprotectant transport system permease protein
E        K05847  opuA; osmoprotectant transport system ATP-binding protein
D      M00442  Putative hydroxymethylpyrimidine transport system [PATH:map02010] [BR:ko02000]
E        K15598  thiY; putative hydroxymethylpyrimidine transport system substrate-binding protein
E        K15599  thiX; putative hydroxymethylpyrimidine transport system permease protein
E        K15600  thiZ; putative hydroxymethylpyrimidine transport system ATP-binding protein
D      M00192  Putative thiamine transport system [BR:ko02000]
E        K05777  ABC.VB1X.S; putative thiamine transport system substrate-binding protein
E        K05778  ABC.VB1X.P; putative thiamine transport system permease protein
E        K05779  ABC.VB1X.A; putative thiamine transport system ATP-binding protein
C    Saccharide and polyol transport system
D      M00194  Maltose/maltodextrin transport system [PATH:map02010] [BR:ko02000]
E        K10108  malE; maltose/maltodextrin transport system substrate-binding protein
E        K10109  malF; maltose/maltodextrin transport system permease protein
E        K10110  malG; maltose/maltodextrin transport system permease protein
E        K10111  malK; maltose/maltodextrin transport system ATP-binding protein [EC:3.6.3.19]
E        K10112  msmX, msmK; maltose/maltodextrin transport system ATP-binding protein
D      M00195  Maltooligosaccharide transport system [PATH:map02010] [BR:ko02000]
E        K10113  ABC.MAL1.S; maltooligosaccharide transport system substrate-binding protein
E        K10114  ABC.MAL1.P; maltooligosaccharide transport system permease protein
E        K10115  ABC.MAL1.P1; maltooligosaccharide transport system permease protein
E        K10116  ABC.MAL1.A; maltooligosaccharide transport system ATP-binding protein
D      M00196  Multiple sugar transport system [PATH:map02010] [BR:ko02000]
E        K10117  msmE; multiple sugar transport system substrate-binding protein
E        K10118  msmF; multiple sugar transport system permease protein
E        K10119  msmG; multiple sugar transport system permease protein
E        K10112  msmX, msmK; maltose/maltodextrin transport system ATP-binding protein
D      M00201  alpha-Glucoside transport system [PATH:map02010] [BR:ko02000]
E        K10232  aglE; alpha-glucoside transport system substrate-binding protein
E        K10233  aglF; alpha-glucoside transport system permease protein
E        K10234  aglG; alpha-glucoside transport system permease protein
E        K10235  aglK; alpha-glucoside transport system ATP-binding protein
D      M00203  Glucose/arabinose transport system [PATH:map02010] [BR:ko02000]
E        K10196  ABC.GLC.S; glucose/arabinose transport system substrate-binding protein
E        K10197  ABC.GLC.P; glucose/arabinose transport system permease protein
E        K10198  ABC.GLC.P1; glucose/arabinose transport system permease protein
E        K10199  ABC.GLC.A; glucose/arabinose transport system ATP-binding protein
D      M00204  Trehalose/maltose transport system [PATH:map02010] [BR:ko02000]
E        K10236  thuE; trehalose/maltose transport system substrate-binding protein
E        K10237  thuF, sugA; trehalose/maltose transport system permease protein
E        K10238  thuG, sugB; trehalose/maltose transport system permease protein
E        K10239  thuK; trehalose/maltose transport system ATP-binding protein
D      M00205  N-Acetylglucosamine transport system [PATH:map02010] [BR:ko02000]
E        K10200  ABC.NGC.S; N-acetylglucosamine transport system substrate-binding protein
E        K10201  ABC.NGC.P; N-acetylglucosamine transport system permease protein
E        K10202  ABC.NGC.P1; N-acetylglucosamine transport system permease protein
D      M00206  Cellobiose transport system [PATH:map02010] [BR:ko02000]
E        K10240  ABC.CEB.S, cebE; cellobiose transport system substrate-binding protein
E        K10241  ABC.CEB.P, cebF; cellobiose transport system permease protein
E        K10242  ABC.CEB.P1, cebG; cellobiose transport system permease protein
E        K10243  ABC.CEB.A, msiK; cellobiose transport system ATP-binding protein
D      M00213  L-Arabinose transport system [PATH:map02010] [BR:ko02000]
E        K10537  araF; L-arabinose transport system substrate-binding protein
E        K10538  araH; L-arabinose transport system permease protein
E        K10539  araG; L-arabinose transport system ATP-binding protein [EC:3.6.3.17]
D      M00199  L-Arabinose/lactose transport system [PATH:map02010] [BR:ko02000]
E        K10188  lacE, araN; lactose/L-arabinose transport system substrate-binding protein
E        K10189  lacF, araP; lactose/L-arabinose transport system permease protein
E        K10190  lacG, araQ; lactose/L-arabinose transport system permease protein
E        K10191  lacK; lactose/L-arabinose transport system ATP-binding protein
D      M00202  Oligogalacturonide transport system [PATH:map02010] [BR:ko02000]
E        K10192  togB; oligogalacturonide transport system substrate-binding protein
E        K10193  togM; oligogalacturonide transport system permease protein
E        K10194  togN; oligogalacturonide transport system permease protein
E        K10195  togA; oligogalacturonide transport system ATP-binding protein
D      M00214  Methyl-galactoside transport system [PATH:map02010] [BR:ko02000]
E        K10540  mglB; methyl-galactoside transport system substrate-binding protein
E        K10541  mglC; methyl-galactoside transport system permease protein
E        K10542  mglA; methyl-galactoside transport system ATP-binding protein [EC:3.6.3.17]
D      M00215  D-Xylose transport system [PATH:map02010] [BR:ko02000]
E        K10543  xylF; D-xylose transport system substrate-binding protein
E        K10544  xylH; D-xylose transport system permease protein
E        K10545  xylG; D-xylose transport system ATP-binding protein [EC:3.6.3.17]
D      M00216  Multiple sugar transport system [PATH:map02010] [BR:ko02000]
E        K10546  ABC.GGU.S, chvE; putative multiple sugar transport system substrate-binding protein
E        K10547  ABC.GGU.P, gguB; putative multiple sugar transport system permease protein
E        K10548  ABC.GGU.A, gguA; putative multiple sugar transport system ATP-binding protein
D      M00217  D-Allose transport system [PATH:map02010] [BR:ko02000]
E        K10549  alsB; D-allose transport system substrate-binding protein
E        K10550  alsC; D-allose transport system permease protein
E        K10551  alsA; D-allose transport system ATP-binding protein [EC:3.6.3.17]
D      M00218  Fructose transport system [PATH:map02010] [BR:ko02000]
E        K10552  frcB; fructose transport system substrate-binding protein
E        K10553  frcC; fructose transport system permease protein
E        K10554  frcA; fructose transport system ATP-binding protein
D      M00219  AI-2 transport system [PATH:map02010] [BR:ko02000]
E        K10555  lsrB; AI-2 transport system substrate-binding protein
E        K10556  lsrC; AI-2 transport system permease protein
E        K10557  lsrD; AI-2 transport system permease protein
E        K10558  lsrA, ego; AI-2 transport system ATP-binding protein
D      M00220  Rhamnose transport system [PATH:map02010] [BR:ko02000]
E        K10559  rhaS1; rhamnose transport system substrate-binding protein
E        K10560  rhaP; rhamnose transport system permease protein
E        K10561  rhaQ; rhamnose transport system permease protein
E        K10562  rhaT; rhamnose transport system ATP-binding protein [EC:3.6.3.17]
D      M00212  Ribose transport system [PATH:map02010] [BR:ko02000]
E        K10439  rbsB; ribose transport system substrate-binding protein
E        K10440  rbsC; ribose transport system permease protein
E        K10441  rbsA; ribose transport system ATP-binding protein [EC:3.6.3.17]
D      M00197  Putative fructooligosaccharide transport system [BR:ko02000]
E        K10108  malE; maltose/maltodextrin transport system substrate-binding protein
E        K10109  malF; maltose/maltodextrin transport system permease protein
E        K10110  malG; maltose/maltodextrin transport system permease protein
E        K10117  msmE; multiple sugar transport system substrate-binding protein
E        K10118  msmF; multiple sugar transport system permease protein
E        K10119  msmG; multiple sugar transport system permease protein
E        K10113  ABC.MAL1.S; maltooligosaccharide transport system substrate-binding protein
E        K10114  ABC.MAL1.P; maltooligosaccharide transport system permease protein
E        K10115  ABC.MAL1.P1; maltooligosaccharide transport system permease protein
E        K10120  ABC.MSM1.S; putative sugar transport system substrate-binding protein
E        K10121  ABC.MSM1.P; putative sugar transport system permease protein
E        K10122  ABC.MSM1.P1; putative sugar transport system permease protein
E        K10111  malK; maltose/maltodextrin transport system ATP-binding protein [EC:3.6.3.19]
E        K10112  msmX, msmK; maltose/maltodextrin transport system ATP-binding protein
E        K10116  ABC.MAL1.A; maltooligosaccharide transport system ATP-binding protein
D      M00198  Putative sn-glycerol-phosphate transport system [PATH:map02010] [BR:ko02000]
E        K05813  ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
E        K05814  ugpA; sn-glycerol 3-phosphate transport system permease protein
E        K05815  ugpE; sn-glycerol 3-phosphate transport system permease protein
E        K05816  ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:3.6.3.20]
D      M00200  Putative sorbitol/mannitol transport system [PATH:map02010] [BR:ko02000]
E        K10227  smoE, mtlE; sorbitol/mannitol transport system substrate-binding protein
E        K10228  smoF, mtlF; sorbitol/mannitol transport system permease protein
E        K10229  smoG, mtlG; sorbitol/mannitol transport system permease protein
E        K10230  smoK, mtlK; sorbitol/mannitol transport system ATP-binding protein
E        K10243  ABC.CEB.A, msiK; cellobiose transport system ATP-binding protein
D      M00491  Putative arabinogalactan oligomer transport system [PATH:map02010] [BR:ko02000]
E        K15770  cycB, ganO; putative arabinogalactan oligomer transport system substrate-binding protein
E        K15771  ganP; putative arabinogalactan oligomer transport system permease protein
E        K15772  ganQ; putative arabinogalactan oligomer transport system permease protein
E        K10111  malK; maltose/maltodextrin transport system ATP-binding protein [EC:3.6.3.19]
E        K10112  msmX, msmK; maltose/maltodextrin transport system ATP-binding protein
D      M00207  Putative multiple sugar transport system [BR:ko02000]
E        K02027  ABC.MS.S; multiple sugar transport system substrate-binding protein
E        K02025  ABC.MS.P; multiple sugar transport system permease protein
E        K02026  ABC.MS.P1; multiple sugar transport system permease protein
E        K02023  ABC.MS.A; multiple sugar transport system ATP-binding protein
D      M00221  Putative simple sugar transport system [BR:ko02000]
E        K02058  ABC.SS.S; simple sugar transport system substrate-binding protein
E        K02057  ABC.SS.P; simple sugar transport system permease protein
E        K02056  ABC.SS.A; simple sugar transport system ATP-binding protein [EC:3.6.3.17]
D      M00210  Putative ABC transport system [BR:ko02000]
E        K02067  ABC.X1.S; putative ABC transport system substrate-binding protein
E        K02066  ABC.X1.P; putative ABC transport system permease protein
E        K02065  ABC.X1.A; putative ABC transport system ATP-binding protein
D      M00211  Putative ABC transport system [BR:ko02000]
E        K02069  ABC.X2.P; putative ABC transport system permease protein
E        K02068  ABC.X2.A; putative ABC transport system ATP-binding protein
C    Phosphate and amino acid transport system
D      M00222  Phosphate transport system [PATH:map02010] [BR:ko02000]
E        K02040  pstS; phosphate transport system substrate-binding protein
E        K02037  pstC; phosphate transport system permease protein
E        K02038  pstA; phosphate transport system permease protein
E        K02036  pstB; phosphate transport system ATP-binding protein [EC:3.6.3.27]
D      M00223  Phosphonate transport system [PATH:map02010] [BR:ko02000]
E        K02044  phnD; phosphonate transport system substrate-binding protein
E        K02042  phnE; phosphonate transport system permease protein
E        K02041  phnC; phosphonate transport system ATP-binding protein [EC:3.6.3.28]
D      M00225  Lysine/arginine/ornithine transport system [PATH:map02010] [BR:ko02000]
E        K10013  ABC.ARG.S, argT; lysine/arginine/ornithine transport system substrate-binding protein
E        K10015  hisM; histidine transport system permease protein
E        K10016  hisQ; histidine transport system permease protein
E        K10017  hisP; histidine transport system ATP-binding protein [EC:3.6.3.21]
D      M00226  Histidine transport system [PATH:map02010] [BR:ko02000]
E        K10014  hisJ; histidine transport system substrate-binding protein
E        K10015  hisM; histidine transport system permease protein
E        K10016  hisQ; histidine transport system permease protein
E        K10017  hisP; histidine transport system ATP-binding protein [EC:3.6.3.21]
D      M00227  Glutamine transport system [PATH:map02010] [BR:ko02000]
E        K10036  glnH; glutamine transport system substrate-binding protein
E        K10037  glnP; glutamine transport system permease protein
E        K10038  glnQ; glutamine transport system ATP-binding protein [EC:3.6.3.-]
D      M00229  Arginine transport system [PATH:map02010] [BR:ko02000]
E        K09996  artJ; arginine transport system substrate-binding protein
E        K09997  artI; arginine transport system substrate-binding protein
E        K09998  artM; arginine transport system permease protein
E        K09999  artQ; arginine transport system permease protein
E        K10000  artP; arginine transport system ATP-binding protein [EC:3.6.3.-]
D      M00230  Glutamate/aspartate transport system [PATH:map02010] [BR:ko02000]
E        K10001  gltI; glutamate/aspartate transport system substrate-binding protein
E        K10002  gltK; glutamate/aspartate transport system permease protein
E        K10003  gltJ; glutamate/aspartate transport system permease protein
E        K10004  gltL; glutamate/aspartate transport system ATP-binding protein [EC:3.6.3.-]
D      M00231  Octopine/nopaline transport system [PATH:map02010] [BR:ko02000]
E        K10018  occT, nocT; octopine/nopaline transport system substrate-binding protein
E        K10019  occM, nocM; octopine/nopaline transport system permease protein
E        K10020  occQ, nocQ; octopine/nopaline transport system permease protein
E        K10021  occP, nocP; octopine/nopaline transport system ATP-binding protein [EC:3.6.3.-]
D      M00232  General L-amino acid transport system [PATH:map02010] [BR:ko02000]
E        K09969  aapJ, bztA; general L-amino acid transport system substrate-binding protein
E        K09970  aapQ, bztB; general L-amino acid transport system permease protein
E        K09971  aapM, bztC; general L-amino acid transport system permease protein
E        K09972  aapP, bztD; general L-amino acid transport system ATP-binding protein [EC:3.6.3.-]
D      M00233  Glutamate transport system [PATH:map02010] [BR:ko02000]
E        K10005  gluB; glutamate transport system substrate-binding protein
E        K10006  gluC; glutamate transport system permease protein
E        K10007  gluD; glutamate transport system permease protein
E        K10008  gluA; glutamate transport system ATP-binding protein [EC:3.6.3.-]
D      M00234  Cystine transport system [PATH:map02010] [BR:ko02000]
E        K02424  fliY; cystine transport system substrate-binding protein
E        K10009  ABC.CYST.P; cystine transport system permease protein
E        K10010  ABC.CYST.A; cystine transport system ATP-binding protein [EC:3.6.3.-]
D      M00585  L-Cystine transport system [PATH:map02010] [BR:ko02000]
E        K16956  tcyJ; L-cystine transport system substrate-binding protein
E        K16957  tcyK; L-cystine transport system substrate-binding protein
E        K16958  tcyL; L-cystine transport system permease protein
E        K16959  tcyM; L-cystine transport system permease protein
E        K16960  tcyN; L-cystine transport system ATP-binding protein [EC:3.6.3.-]
D      M00235  Arginine/ornithine transport system [PATH:map02010] [BR:ko02000]
E        K10022  aotJ; arginine/ornithine transport system substrate-binding protein
E        K10023  aotM; arginine/ornithine transport system permease protein
E        K10024  aotQ; arginine/ornithine transport system permease protein
E        K10025  aotP; arginine/ornithine transport system ATP-binding protein [EC:3.6.3.-]
D      M00237  Branched-chain amino acid transport system [PATH:map02010] [BR:ko02000]
E        K01999  livK; branched-chain amino acid transport system substrate-binding protein
E        K01997  livH; branched-chain amino acid transport system permease protein
E        K01998  livM; branched-chain amino acid transport system permease protein
E        K01995  livG; branched-chain amino acid transport system ATP-binding protein
E        K01996  livF; branched-chain amino acid transport system ATP-binding protein
D      M00322  Neutral amino acid transport system [PATH:map02010] [BR:ko02000]
E        K11954  K11954, natB; neutral amino acid transport system substrate-binding protein
E        K11955  natC; neutral amino acid transport system permease protein
E        K11956  natD; neutral amino acid transport system permease protein
E        K11957  K11957, natA; neutral amino acid transport system ATP-binding protein
E        K11958  natE; neutral amino acid transport system ATP-binding protein
D      M00323  Urea transport system [PATH:map02010] [BR:ko02000]
E        K11959  urtA; urea transport system substrate-binding protein
E        K11960  urtB; urea transport system permease protein
E        K11961  urtC; urea transport system permease protein
E        K11962  urtD; urea transport system ATP-binding protein
E        K11963  urtE; urea transport system ATP-binding protein
D      M00238  D-Methionine transport system [PATH:map02010] [BR:ko02000]
E        K02073  metQ; D-methionine transport system substrate-binding protein
E        K02072  metI; D-methionine transport system permease protein
E        K02071  metN; D-methionine transport system ATP-binding protein
D      M00224  Putative phosphonate transport system [PATH:map02010] [BR:ko02000]
E        K16905  K16905; fluoroquinolones transport system permease protein
E        K16906  K16906; fluoroquinolones transport system permease protein
E        K16907  K16907; fluoroquinolones transport system ATP-binding protein [EC:3.6.3.-]
D      M00228  Putative glutamine transport system [PATH:map02010] [BR:ko02000]
E        K10039  ABC.GLN1.S; putative glutamine transport system substrate-binding protein
E        K10040  ABC.GLN1.P; putative glutamine transport system permease protein
E        K10041  ABC.GLN1.A; putative glutamine transport system ATP-binding protein [EC:3.6.3.-]
D      M00586  Putative amino-acid transport system [PATH:map02010] [BR:ko02000]
E        K16961  yxeM; putative amino-acid transport system substrate-binding protein
E        K16962  yxeN; putative amino-acid transport system permease protein
E        K16963  yxeO; putative amino-acid transport system ATP-binding protein [EC:3.6.3.-]
D      M00236  Putative polar amino acid transport system [BR:ko02000]
E        K02030  ABC.PA.S; polar amino acid transport system substrate-binding protein
E        K02029  ABC.PA.P; polar amino acid transport system permease protein
E        K02028  ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21]
C    Peptide and nickel transport system
D      M00439  Oligopeptide transport system [PATH:map02010] [BR:ko02000]
E        K15580  oppA, mppA; oligopeptide transport system substrate-binding protein
E        K15581  oppB; oligopeptide transport system permease protein
E        K15582  oppC; oligopeptide transport system permease protein
E        K15583  oppD; oligopeptide transport system ATP-binding protein
E        K10823  oppF; oligopeptide transport system ATP-binding protein
D      M00324  Dipeptide transport system [PATH:map02010] [BR:ko02000]
E        K12368  dppA; dipeptide transport system substrate-binding protein
E        K12369  dppB; dipeptide transport system permease protein
E        K12370  dppC; dipeptide transport system permease protein
E        K12371  dppD; dipeptide transport system ATP-binding protein
E        K12372  dppF; dipeptide transport system ATP-binding protein
D      M00566  Dipeptide transport system, Firmicutes [PATH:map02010] [BR:ko02000]
E        K16199  dppE; dipeptide transport system substrate-binding protein
E        K16200  dppB1; dipeptide transport system permease protein
E        K16201  dppC1; dipeptide transport system permease protein
E        K16202  dppD1; dipeptide transport system ATP-binding protein
D      M00440  Nickel transport system [PATH:map02010] [BR:ko02000]
E        K15584  nikA; nickel transport system substrate-binding protein
E        K15585  nikB; nickel transport system permease protein
E        K15586  nikC; nickel transport system permease protein
E        K15587  nikD; nickel transport system ATP-binding protein [EC:3.6.3.24]
E        K10824  nikE; nickel transport system ATP-binding protein [EC:3.6.3.24]
D      M00348  Glutathione transport system [PATH:map02010] [BR:ko02000]
E        K13889  gsiB; glutathione transport system substrate-binding protein
E        K13890  gsiC; glutathione transport system permease protein
E        K13891  gsiD; glutathione transport system permease protein
E        K13892  gsiA; glutathione transport system ATP-binding protein
D      M00239  Peptides/nickel transport system [PATH:map02010] [BR:ko02000]
E        K02035  ABC.PE.S; peptide/nickel transport system substrate-binding protein
E        K02033  ABC.PE.P; peptide/nickel transport system permease protein
E        K02034  ABC.PE.P1; peptide/nickel transport system permease protein
E        K02031  ABC.PE.A; peptide/nickel transport system ATP-binding protein
E        K02032  ABC.PE.A1; peptide/nickel transport system ATP-binding protein
D      M00349  Microcin C transport system [PATH:map02010] [BR:ko02000]
E        K13893  yejA; microcin C transport system substrate-binding protein
E        K13894  yejB; microcin C transport system permease protein
E        K13895  yejE; microcin C transport system permease protein
E        K13896  yejF; microcin C transport system ATP-binding protein
C    Metallic cation, iron-siderophore and vitamin B12 transport system
D      M00240  Iron complex transport system [PATH:map02010] [BR:ko02000]
E        K02016  ABC.FEV.S; iron complex transport system substrate-binding protein
E        K02015  ABC.FEV.P; iron complex transport system permease protein
E        K02013  ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]
D      M00241  Vitamin B12 transport system [PATH:map02010] [BR:ko02000]
E        K06858  ABC.VB12.S1, btuF; vitamin B12 transport system substrate-binding protein
E        K06073  ABC.VB12.P, btuC; vitamin B12 transport system permease protein
E        K06074  ABC.VB12.A, btuD; vitamin B12 transport system ATP-binding protein [EC:3.6.3.33]
D      M00316  Manganese transport system [PATH:map02010 map02020] [BR:ko02000]
E        K11601  mntC; manganese transport system substrate-binding protein
E        K11602  mntB; manganese transport system permease protein
E        K11603  mntA; manganese transport system ATP-binding protein
D      M00242  Zinc transport system [PATH:map02010] [BR:ko02000]
E        K09815  znuA; zinc transport system substrate-binding protein
E        K09816  znuB; zinc transport system permease protein
E        K09817  znuC; zinc transport system ATP-binding protein [EC:3.6.3.-]
D      M00318  Iron/zinc/copper transport system [PATH:map02010] [BR:ko02000]
E        K11704  mtsA; iron/zinc/copper transport system substrate-binding protein
E        K11705  mtsB; iron/zinc/copper transport system permease protein
E        K11706  mtsC; iron/zinc/copper transport system ATP-binding protein
D      M00317  Manganese/iron transport system [PATH:map02010] [BR:ko02000]
E        K11604  sitA; manganese/iron transport system substrate-binding protein
E        K11605  sitC; manganese/iron transport system permease protein
E        K11606  sitD; manganese/iron transport system permease protein
E        K11607  sitB; manganese/iron transport system ATP-binding protein
D      M00319  Manganese/zinc/iron transport system [PATH:map02010] [BR:ko02000]
E        K11707  troA, mntA, znuA; manganese/zinc/iron transport system substrate-binding protein
E        K11708  troC, mntC, znuB; manganese/zinc/iron transport system permease protein
E        K11709  troD, mntD, znuB; manganese/zinc/iron transport system permease protein
E        K11710  troB, mntB, znuC; manganese/zinc/iron transport system ATP- binding protein
D      M00243  Manganese/iron transport system [BR:ko02000]
E        K09818  ABC.MN.S; manganese/iron transport system substrate-binding protein
E        K09819  ABC.MN.P; manganese/iron transport system permease protein
E        K09820  ABC.MN.A; manganese/iron transport system ATP-binding protein
D      M00245  Cobalt transport system [PATH:map02010] [BR:ko02000]
E        K02009  cbiN; cobalt/nickel transport protein
E        K02008  cbiQ; cobalt/nickel transport system permease protein
E        K02007  cbiM; cobalt/nickel transport system permease protein
E        K02006  cbiO; cobalt/nickel transport system ATP-binding protein
D      M00246  Nickel transport system [PATH:map02010] [BR:ko02000]
E        K10094  K10094, cbiK; nickel transport protein
E        K16915  cbiL; nickel transport protein
E        K02009  cbiN; cobalt/nickel transport protein
E        K02008  cbiQ; cobalt/nickel transport system permease protein
E        K02007  cbiM; cobalt/nickel transport system permease protein
E        K02006  cbiO; cobalt/nickel transport system ATP-binding protein
D      M00581  Biotin transport system [PATH:map02010] [BR:ko02000]
E        K03523  bioY; biotin transport system substrate-specific component
E        K16783  bioN; biotin transport system permease protein
E        K16784  bioM; biotin transport system ATP-binding protein [EC:3.6.3.-]
D      M00582  Energy-coupling factor transport system [PATH:map02010] [BR:ko02000]
E        K03523  bioY; biotin transport system substrate-specific component
E        K16923  qrtT; energy-coupling factor transport system substrate-specific component
E        K16924  mtsT; energy-coupling factor transport system substrate-specific component
E        K16925  ykoE; energy-coupling factor transport system substrate-specific component
E        K16926  htsT; energy-coupling factor transport system substrate-specific component
E        K16927  cbrT; energy-coupling factor transport system substrate-specific component
E        K16928  mtaT; energy-coupling factor transport system substrate-specific component
E        K16929  K16929; energy-coupling factor transport system substrate-specific component
E        K16785  ecfT; energy-coupling factor transport system permease protein
E        K16786  ecfA1; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]
E        K16787  ecfA2; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]
D      M00244  Putative zinc/manganese transport system [BR:ko02000]
E        K02077  ABC.ZM.S; zinc/manganese transport system substrate-binding protein
E        K02075  ABC.ZM.P; zinc/manganese transport system permease protein
E        K02074  ABC.ZM.A; zinc/manganese transport system ATP-binding protein
D      M00247  Putative ABC transport system [BR:ko02000]
E        K01989  ABC.X4.S; putative ABC transport system substrate-binding protein
E        K05832  ABC.X4.P; putative ABC transport system permease protein
E        K05833  ABC.X4.A; putative ABC transport system ATP-binding protein
C    ABC-2 type and other transport systems
D      M00298  Multidrug/hemolysin transport system [PATH:map02010] [BR:ko02000]
E        K11051  ABC-2.CYL.P, cylB; multidrug/hemolysin transport system permease protein
E        K11050  ABC-2.CYL.A, cylA; multidrug/hemolysin transport system ATP-binding protein
D      M00249  Capsular polysaccharide transport system [PATH:map02010] [BR:ko02000]
E        K09688  ABC-2.CPSE.P; capsular polysaccharide transport system permease protein
E        K10107  ABC-2.CPSE.P1; capsular polysaccharide transport system permease protein
E        K09689  ABC-2.CPSE.A; capsular polysaccharide transport system ATP-binding protein
D      M00250  Lipopolysaccharide transport system [PATH:map02010] [BR:ko02000]
E        K09690  ABC-2.LPSE.P; lipopolysaccharide transport system permease protein
E        K09691  ABC-2.LPSE.A; lipopolysaccharide transport system ATP-binding protein
D      M00320  Lipopolysaccharide export system [PATH:map02010] [BR:ko02000]
E        K07091  lptF; lipopolysaccharide export system permease protein
E        K11720  lptG; lipopolysaccharide export system permease protein
E        K06861  lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-]
D      M00251  Teichoic acid transport system [PATH:map02010] [BR:ko02000]
E        K09692  tagG; teichoic acid transport system permease protein
E        K09693  tagH; teichoic acid transport system ATP-binding protein [EC:3.6.3.40]
D      M00252  Lipooligosaccharide transport system [PATH:map02010] [BR:ko02000]
E        K09694  nodJ; lipooligosaccharide transport system permease protein
E        K09695  nodI; lipooligosaccharide transport system ATP-binding protein
D      M00253  Sodium transport system [PATH:map02010] [BR:ko02000]
E        K09696  natB; sodium transport system permease protein
E        K09697  natA; sodium transport system ATP-binding protein
D      M00583  Putative peptide transport system [PATH:map02010] [BR:ko02000]
E        K16916  yydJ; putative peptide transport system permease protein
E        K16917  yydI; putative peptide transport system ATP-binding protein
D      M00257  Hemin transport system [PATH:map02010] [BR:ko02000]
E        K09813  hrtB; hemin transport system permease protein
E        K09814  hrtA; hemin transport system ATP-binding protein [EC:3.6.3.-]
D      M00314  Bacitracin transport system [PATH:map02010 map02020] [BR:ko02000]
E        K11632  bceB; bacitracin transport system permease protein
E        K11631  bceA; bacitracin transport system ATP-binding protein
D      M00224  Fluoroquinolones transport system [PATH:map02010] [BR:ko02000]
E        K16905  K16905; fluoroquinolones transport system permease protein
E        K16906  K16906; fluoroquinolones transport system permease protein
E        K16907  K16907; fluoroquinolones transport system ATP-binding protein [EC:3.6.3.-]
D      M00255  Lipoprotein-releasing system [PATH:map02010] [BR:ko02000]
E        K09808  ABC.LPT.P, lolC, lolE; lipoprotein-releasing system permease protein
E        K09810  ABC.LPT.A, lolD; lipoprotein-releasing system ATP-binding protein [EC:3.6.3.-]
D      M00584  Acetoin utilization transport system [PATH:map02010] [BR:ko02000]
E        K16918  ytrF; acetoin utilization transport system permease protein
E        K16919  ytrC_D; acetoin utilization transport system permease protein
E        K16920  ytrE; acetoin utilization transport system ATP-binding protein
E        K16921  ytrB; acetoin utilization transport system ATP-binding protein
D      M00259  Heme transport system [PATH:map02010] [BR:ko02000]
E        K02195  ccmC; heme exporter protein C
E        K02194  ccmB; heme exporter protein B
E        K02193  ccmA; heme exporter protein A [EC:3.6.3.41]
D      M00256  Cell division transport system [PATH:map02010] [BR:ko02000]
E        K09811  ftsX; cell division transport system permease protein
E        K09812  ftsE; cell division transport system ATP-binding protein
D      M00315  Uncharacterized ABC transport system [PATH:map02020] [BR:ko02000]
E        K11636  yxdM; putative ABC transport system permease protein
E        K11635  yxdL; putative ABC transport system ATP-binding protein
D      M00248  Putative antibiotic transport system [PATH:map02010] [BR:ko02000]
E        K09686  ABC-2.AB.P; antibiotic transport system permease protein
E        K09687  ABC-2.AB.A; antibiotic transport system ATP-binding protein
D      M00258  Putative ABC transport system [BR:ko02000]
E        K02004  ABC.CD.P; putative ABC transport system permease protein
E        K02003  ABC.CD.A; putative ABC transport system ATP-binding protein
D      M00254  ABC-2 type transport system [BR:ko02000]
E        K01992  ABC-2.P; ABC-2 type transport system permease protein
E        K01990  ABC-2.A; ABC-2 type transport system ATP-binding protein
C    Phosphotransferase system (PTS)
D      M00265  PTS system, glucose-specific II component [PATH:map00010 map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K02778  PTS-Glc-EIIB, ptsG; PTS system, glucose-specific IIB component [EC:2.7.1.69]
E        K02779  PTS-Glc-EIIC, ptsG; PTS system, glucose-specific IIC component
D      M00267  PTS system, N-acetylglucosamine-specific II component [PATH:map00520 map02060] [BR:ko02000]
E        K02802  PTS-Nag-EIIA, nagE; PTS system, N-acetylglucosamine-specific IIA component [EC:2.7.1.69]
E        K02803  PTS-Nag-EIIB, nagE; PTS system, N-acetylglucosamine-specific IIB component [EC:2.7.1.69]
E        K02804  PTS-Nag-EIIC, nagE; PTS system, N-acetylglucosamine-specific IIC component
D      M00266  PTS system, maltose and glucose-specific II component [PATH:map00010 map00500 map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K02790  PTS-Mal-EIIB, malX; PTS system, maltose and glucose-specific IIB component [EC:2.7.1.69]
E        K02791  PTS-Mal-EIIC, malX; PTS system, maltose and glucose-specific IIC component
D      M00282  PTS system, D-glucosamine-specific II component [PATH:map00520 map02060] [BR:ko02000]
E        K02763  PTS-Dgl-EIIA, gamP; PTS system, D-glucosamine-specific IIA component [EC:2.7.1.69]
E        K02764  PTS-Dgl-EIIB, gamP; PTS system, D-glucosamine-specific IIB component [EC:2.7.1.69]
E        K02765  PTS-Dgl-EIIC, gamP; PTS system, D-glucosamine-specific IIC component
D      M00269  PTS system, sucrose-specific II component [PATH:map00500 map02060] [BR:ko02000]
E        K02808  PTS-Scr-EIIA, scrA; PTS system, sucrose-specific IIA component [EC:2.7.1.69]
E        K02809  PTS-Scr-EIIB, scrA; PTS system, sucrose-specific IIB component [EC:2.7.1.69]
E        K02810  PTS-Scr-EIIC, scrA; PTS system, sucrose-specific IIC component
D      M00271  PTS system, beta-glucosides-specific II component [PATH:map02060] [BR:ko02000]
E        K02755  PTS-Bgl-EIIA, bglF; PTS system, beta-glucosides-specific IIA component [EC:2.7.1.69]
E        K02756  PTS-Bgl-EIIB, bglF; PTS system, beta-glucosides-specific IIB component [EC:2.7.1.69]
E        K02757  PTS-Bgl-EIIC, bglF; PTS system, beta-glucosides-specific IIC component
D      M00272  PTS system, arbutin-, cellobiose-, and salicin-specific II component [PATH:map00010 map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K02752  PTS-Asc-EIIB, ascF; PTS system, arbutin-, cellobiose-, and salicin-specific IIB component [EC:2.7.1.69]
E        K02753  PTS-Asc-EIIC, ascF; PTS system, arbutin-, cellobiose-, and salicin-specific IIC component
D      M00270  PTS system, trehalose-specific II component [PATH:map00500 map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K02817  PTS-Tre-EIIA, treP; PTS system, trehalose-specific IIA component [EC:2.7.1.69]
E        K02818  PTS-Tre-EIIB, treB; PTS system, trehalose-specific IIB component [EC:2.7.1.69]
E        K02819  PTS-Tre-EIIC, treB; PTS system, trehalose-specific IIC component
D      M00303  PTS system, N-acetylmuramic acid-specific II component [PATH:map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K11191  PTS-Mur-EIIB, murP; PTS system, N-acetylmuramic acid-specific IIB component [EC:2.7.1.69]
E        K11192  PTS-Mur-EIIC, murP; PTS system, N-acetylmuramic acid-specific IIC component
D      M00268  PTS system, arbutin-like II component [PATH:map00010 map02060] [BR:ko02000]
E        K02777  PTS-Glc-EIIA, crr; PTS system, glucose-specific IIA component [EC:2.7.1.69]
E        K02749  PTS-Arb-EIIB, glvB; PTS system, arbutin-like IIB component [EC:2.7.1.69]
E        K02750  PTS-Arb-EIIC, glvC; PTS system, arbutin-like IIC component
D      M00273  PTS system, fructose-specific II component [PATH:map00051 map02060] [BR:ko02000]
E        K02768  PTS-Fru-EIIA, fruB; PTS system, fructose-specific IIA component [EC:2.7.1.69]
E        K02769  PTS-Fru-EIIB, fruA; PTS system, fructose-specific IIB component [EC:2.7.1.69]
E        K02770  PTS-Fru-EIIC, fruA; PTS system, fructose-specific IIC component
D      M00306  PTS system, fructose-specific II-like component [BR:ko02000]
E        K11201  PTS-Fru2-EIIA; PTS system, fructose-specific IIA-like component [EC:2.7.1.69]
E        K11202  PTS-Fru2-EIIB; PTS system, fructose-specific IIB-like component [EC:2.7.1.69]
E        K11203  PTS-Fru2-EIIC; PTS system, fructose-specific IIC-like component
D      M00274  PTS system, mannitol-specific II component [PATH:map00051 map02060] [BR:ko02000]
E        K02798  PTS-Mtl-EIIA, mtlA; PTS system, mannitol-specific IIA component [EC:2.7.1.69]
E        K02799  PTS-Mtl-EIIB, mtlA; PTS system, mannitol-specific IIB component [EC:2.7.1.69]
E        K02800  PTS-Mtl-EIIC, mtlA; PTS system, mannitol-specific IIC component
D      M00305  PTS system, 2-O-A-mannosyl-D-glycerate-specific II component [PATH:map02060] [BR:ko02000]
E        K11198  PTS-Mng-EIIA, mngA, hrsA; PTS system, 2-O-A-mannosyl-D-glycerate-specific IIA component [EC:2.7.1.69]
E        K11199  PTS-Mng-EIIB, mngA, hrsA; PTS system, 2-O-A-mannosyl-D-glycerate-specific IIB component [EC:2.7.1.69]
E        K11200  PTS-Mng-EIIC, mngA, hrsA; PTS system, 2-O-A-mannosyl-D-glycerate-specific IIC component
D      M00281  PTS system, lactose-specific II component [PATH:map00052 map02060] [BR:ko02000]
E        K02786  PTS-Lac-EIIA, lacF; PTS system, lactose-specific IIA component [EC:2.7.1.69]
E        K02787  PTS-Lac-EIIB, lacE; PTS system, lactose-specific IIB component [EC:2.7.1.69]
E        K02788  PTS-Lac-EIIC, lacE; PTS system, lactose-specific IIC component
D      M00275  PTS system, cellobiose-specific II component [PATH:map02060] [BR:ko02000]
E        K02759  PTS-Cel-EIIA, celC; PTS system, cellobiose-specific IIA component [EC:2.7.1.69]
E        K02760  PTS-Cel-EIIB, celA; PTS system, cellobiose-specific IIB component [EC:2.7.1.69]
E        K02761  PTS-Cel-EIIC, celB; PTS system, cellobiose-specific IIC component
D      M00280  PTS system, glucitol/sorbitol-specific II component [PATH:map00051 map02060] [BR:ko02000]
E        K02781  PTS-Gut-EIIA, srlB; PTS system, glucitol/sorbitol-specific IIA component [EC:2.7.1.69]
E        K02782  PTS-Gut-EIIB, srlE; PTS system, glucitol/sorbitol-specific IIB component [EC:2.7.1.69]
E        K02783  PTS-Gut-EIIC, srlA; PTS system, glucitol/sorbitol-specific IIC component
D      M00279  PTS system, galactitol-specific II component [PATH:map00052 map02060] [BR:ko02000]
E        K02773  PTS-Gat-EIIA, gatA; PTS system, galactitol-specific IIA component [EC:2.7.1.69]
E        K02774  PTS-Gat-EIIB, gatB; PTS system, galactitol-specific IIB component [EC:2.7.1.69]
E        K02775  PTS-Gat-EIIC, gatC; PTS system, galactitol-specific IIC component
D      M00276  PTS system, mannose-specific II component [PATH:map00051 map02060] [BR:ko02000]
E        K02793  PTS-Man-EIIA, manX; PTS system, mannose-specific IIA component [EC:2.7.1.69]
E        K02794  PTS-Man-EIIB, manX; PTS system, mannose-specific IIB component [EC:2.7.1.69]
E        K02795  PTS-Man-EIIC, manY; PTS system, mannose-specific IIC component
E        K02796  PTS-Man-EIID, manZ; PTS system, mannose-specific IID component
D      M00304  PTS system, fructose-specific II component [PATH:map02060] [BR:ko02000]
E        K11194  PTS-Fru1-EIIA, levD; PTS system, fructose-specific IIA component [EC:2.7.1.69]
E        K11195  PTS-Fru1-EIIB, levE; PTS system, fructose-specific IIB component [EC:2.7.1.69]
E        K11196  PTS-Fru1-EIIC, levF; PTS system, fructose-specific IIC component
E        K02771  PTS-Fru1-EIID, levG; PTS system, fructose-specific IID component
D      M00278  PTS system, sorbose-specific II component [PATH:map00051 map02060] [BR:ko02000]
E        K02812  PTS-Sor-EIIA, sorF; PTS system, sorbose-specific IIA component [EC:2.7.1.69]
E        K02813  PTS-Sor-EIIB, sorB; PTS system, sorbose-specific IIB component [EC:2.7.1.69]
E        K02814  PTS-Sor-EIIC, sorA; PTS system, sorbose-specific IIC component
E        K02815  PTS-Sor-EIID, sorM; PTS system, sorbose-specific IID component
D      M00277  PTS system, N-acetylgalactosamine-specific II component [PATH:map00052 map02060] [BR:ko02000]
E        K02744  PTS-Aga-EIIA, agaF; PTS system, N-acetylgalactosamine-specific IIA component [EC:2.7.1.69]
E        K02745  PTS-Aga-EIIB, agaV; PTS system, N-acetylgalactosamine-specific IIB component [EC:2.7.1.69]
E        K02746  PTS-Aga-EIIC, agaW; PTS system, N-acetylgalactosamine-specific IIC component
E        K02747  PTS-Aga-EIID, agaE; PTS system, N-acetylgalactosamine-specific IID component
D      M00287  PTS system, galactosamine-specific II component [PATH:map00052 map02060] [BR:ko02000]
E        K02744  PTS-Aga-EIIA, agaF; PTS system, N-acetylgalactosamine-specific IIA component [EC:2.7.1.69]
E        K10984  PTS-Gam-EIIB, agaB; PTS system, galactosamine-specific IIB component [EC:2.7.1.69]
E        K10985  PTS-Gam-EIIC, agaC; PTS system, galactosamine-specific IIC component
E        K10986  PTS-Gam-EIID, agaD; PTS system, galactosamine-specific IID component
D      M00283  PTS system, ascorbate-specific II component [PATH:map00053 map02060] [BR:ko02000]
E        K02821  PTS-Ula-EIIA, ulaC, sgaA; PTS system, ascorbate-specific IIA component [EC:2.7.1.69]
E        K02822  PTS-Ula-EIIB, ulaB, sgaB; PTS system, ascorbate-specific IIB component [EC:2.7.1.69]
E        K03475  PTS-Ula-EIIC, ulaA, sgaT; PTS system, ascorbate-specific IIC component
C    Bacterial secretion system
D      M00325  alpha-Hemolysin/cyclolysin transport system [PATH:map02010 map03070] [BR:ko02000]
E        K11004  hlyB, cyaB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
E        K11003  hlyD, cyaD; hemolysin D
E        K12340  tolC; outer membrane channel protein
D      M00326  RTX toxin transport system [BR:ko02044]
E        K12530  rtxB; ATP-binding cassette, subfamily B, bacterial RtxB
E        K12531  rtxE; ATP-binding cassette, subfamily B, bacterial RtxE
E        K12532  rtxD; RTX toxin transporter
E        K12340  tolC; outer membrane channel protein
D      M00327  S-Layer protein transport system [BR:ko02044]
E        K12533  rsaD; ATP-binding cassette, subfamily C, bacterial RsaD
E        K12534  rsaE; membrane fusion protein RsaE
E        K12535  rsaF; outer membrane protein RsaF
D      M00328  Hemophore/metalloprotease transport system [BR:ko02044]
E        K12536  hasD, prtD, aprD; ATP-binding cassette, subfamily C, bacterial exporter for protease/lipase
E        K12537  hasE, prtE; protease secretion protein HasE
E        K12538  hasF, prtF; outer membrane protein HasF
D      M00329  Multiple protein transport system [BR:ko02044]
E        K12539  prsD; ATP-binding cassette, subfamily C, bacterial PrsD
E        K12540  prsE; membrane fusion protein PrsE
D      M00330  Adhesin protein transport system [BR:ko02044]
E        K12541  lapB; ATP-binding cassette, subfamily C, bacterial LapB
E        K12542  lapC; membrane fusion protein LapC
E        K12543  lapE; outer membrane protein LapE
D      M00571  AlgE-type Mannuronan C-5-Epimerase transport system [BR:ko02044]
E        K16300  eexE; membrane fusion protein EexE
E        K16299  eexD; ATP-binding cassette, subfamily C, bacterial EexD
E        K12340  tolC; outer membrane channel protein
D      M00339  RaxAB-RaxC type I secretion system [PATH:map04626] [BR:ko02044]
E        K13408  raxA; membrane fusion protein RaxA
E        K13409  raxB, cvaB; ATP-binding cassette, subfamily B, bacterial RaxB
E        K12340  tolC; outer membrane channel protein
D      M00331  Type II general secretion system [PATH:map03070] [BR:ko02044]
E        K02453  gspD; general secretion pathway protein D
E        K02465  gspS; general secretion pathway protein S
E        K02452  gspC; general secretion pathway protein C
E        K02455  gspF; general secretion pathway protein F
E        K02456  gspG; general secretion pathway protein G
E        K02457  gspH; general secretion pathway protein H
E        K02458  gspI; general secretion pathway protein I
E        K02459  gspJ; general secretion pathway protein J
E        K02460  gspK; general secretion pathway protein K
E        K02461  gspL; general secretion pathway protein L
E        K02462  gspM; general secretion pathway protein M
E        K02454  gspE; general secretion pathway protein E
E        K02464  gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]
D      M00332  Type III secretion system [PATH:map03070] [BR:ko02044]
E        K03221  yscF; type III secretion protein SctF
E        K04056  yscO; type III secretion protein SctO
E        K04057  yscP; type III secretion protein SctP
E        K04059  yscX; type III secretion protein SctX
E        K03219  yscC; type III secretion protein SctC
E        K04058  yscW; type III secretion protein SctW
E        K03222  yscJ; type III secretion protein SctJ
E        K03226  yscR; type III secretion protein SctR
E        K03227  yscS; type III secretion protein SctS
E        K03228  yscT; type III secretion protein SctT
E        K03229  yscU; type III secretion protein SctU
E        K03230  yscV; type III secretion protein SctV
E        K03224  yscN; ATP synthase in type III secretion protein SctN [EC:3.6.3.14]
E        K03225  yscQ; type III secretion protein SctQ
E        K03223  yscL; type III secretion protein SctL
D      M00333  Type IV secretion system [PATH:map03070] [BR:ko02044]
E        K03194  virB1; type IV secretion system protein VirB1
E        K03197  virB2, lvhB2; type IV secretion system protein VirB2
E        K03198  virB3, lvhB3; type IV secretion system protein VirB3
E        K03200  virB5, lvhB5; type IV secretion system protein VirB5
E        K03202  virB7, lvhB7; type IV secretion system protein VirB7
E        K03204  virB9, lvhB9; type IV secretion system protein VirB9
E        K03201  virB6, lvhB6; type IV secretion system protein VirB6
E        K03203  virB8, lvhB8; type IV secretion system protein VirB8
E        K03195  virB10, lvhB10; type IV secretion system protein VirB10
E        K03199  virB4, lvhB4; type IV secretion system protein VirB4
E        K03196  virB11, lvhB11; type IV secretion system protein VirB11
E        K03205  virD4, lvhD4; type IV secretion system protein VirD4
D      M00334  Type VI secretion system [PATH:map03070] [BR:ko02044]
E        K11904  vgrG; type VI secretion system secreted protein VgrG
E        K11903  K11903, hcp; type VI secretion system secreted protein Hcp
E        K11906  vasD, lip; type VI secretion system protein VasD
E        K11891  impL, vasK, icmF; type VI secretion system protein ImpL
E        K11892  impK, ompA, vasF, dotU; type VI secretion system protein ImpK
E        K11907  vasG, clpV; type VI secretion system protein VasG
E        K11912  ppkA; serine/threonine-protein kinase PpkA [EC:2.7.11.1]
E        K11913  fha1; type VI secretion system protein
E        K11915  stp1, pppA; serine/threonine protein phosphatase Stp1 [EC:3.1.3.16]
D      M00335  Sec (secretion) system [PATH:map03070] [BR:ko02044]
E        K03072  secD; preprotein translocase subunit SecD
E        K03074  secF; preprotein translocase subunit SecF
E        K12257  secDF; SecD/SecF fusion protein
E        K03073  secE; preprotein translocase subunit SecE
E        K03075  secG; preprotein translocase subunit SecG
E        K13301  secM; secretion monitor
E        K03076  secY; preprotein translocase subunit SecY
E        K03210  yajC; preprotein translocase subunit YajC
E        K03217  yidC, spoIIIJ, OXA1; preprotein translocase subunit YidC
E        K03070  secA; preprotein translocase subunit SecA
E        K03110  ftsY; fused signal recognition particle receptor
E        K03071  secB; preprotein translocase subunit SecB
E        K03106  SRP54, ffh; signal recognition particle subunit SRP54
D      M00336  Twin-arginine translocation (Tat) system [PATH:map03070] [BR:ko02044]
E        K03116  tatA; sec-independent protein translocase protein TatA
E        K03117  tatB; sec-independent protein translocase protein TatB
E        K03118  tatC; sec-independent protein translocase protein TatC
E        K03425  tatE; sec-independent protein translocase protein TatE
D      M00429  Competence-related DNA transformation transporter [BR:ko02044]
E        K02237  comEA; competence protein ComEA
E        K02238  comEC; competence protein ComEC
E        K02240  comFA; competence protein ComFA
E        K02243  comGA; competence protein ComGA
E        K02244  comGB; competence protein ComGB
E        K02245  comGC; competence protein ComGC
E        K02246  comGD; competence protein ComGD
E        K02247  comGE; competence protein ComGE
E        K02248  comGF; competence protein ComGF
E        K02249  comGG; competence protein ComGG
#
A<b>Functional set</b>
B
B  <b>Metabolism</b>
C    Aminoacyl tRNA
D      M00360  Aminoacyl-tRNA biosynthesis, prokaryotes [PATH:map00970]
E        K01872  AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]
E        K01887  RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]
E        K01893  NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
E        K01876  DARS, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]
E        K09759  aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
E        K01883  CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
E        K01886  QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
E        K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]
E        K09698  gltX1; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
E        K01878  glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
E        K01879  glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
E        K14164  glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]
E        K01880  GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14]
E        K01892  HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]
E        K01870  IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
E        K01869  LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]
E        K04567  KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
E        K04566  lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
E        K01874  MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]
E        K01889  FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
E        K01890  FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
E        K01881  PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]
E        K01875  SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]
E        K01868  TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]
E        K01867  WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
E        K01866  YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
E        K01873  VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]
E        K07587  sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
E        K11627  pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
E        K04568  poxA; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
E        K01884  cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
D      M00359  Aminoacyl-tRNA biosynthesis, eukaryotes [PATH:map00970]
E        K01872  AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]
E        K01887  RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]
E        K01893  NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
E        K01876  DARS, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]
E        K01883  CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
E        K01886  QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
E        K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]
E        K01880  GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14]
E        K01892  HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]
E        K01870  IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
E        K01869  LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]
E        K04567  KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
E        K01874  MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]
E        K01889  FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
E        K01890  FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
E        K01881  PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]
E        K01875  SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]
E        K01868  TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]
E        K01867  WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
E        K01866  YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
E        K01873  VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]
E        K14163  EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
C    Nucleotide sugar
D      M00362  Nucleotide sugar biosynthesis, prokaryotes [PATH:map00520]
E        K00963  UGP2, galU, galF; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
E        K00965  galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
E        K01784  galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]
E        K00972  UAP1; UDP-N-acetylglucosamine pyrophosphorylase [EC:2.7.7.23]
E        K04042  glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
E        K11528  glmU1; UDP-N-acetylglucosamine pyrophosphorylase [EC:2.7.7.23]
E        K01791  wecB; UDP-N-acetylglucosamine 2-epimerase [EC:5.1.3.14]
E        K00012  UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
E        K00966  GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
E        K00971  manC, cpsB; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
E        K16011  algA, xanB, rfbA; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
E        K16881  K16881; mannose-1-phosphate guanylyltransferase / phosphomannomutase [EC:2.7.7.13 5.4.2.8]
D      M00361  Nucleotide sugar biosynthesis, eukaryotes [PATH:map00520]
E        K00963  UGP2, galU, galF; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
E        K01784  galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]
E        K15917  GAL10; UDP-glucose 4-epimerase / aldose 1-epimerase [EC:5.1.3.2 5.1.3.3]
E        K00972  UAP1; UDP-N-acetylglucosamine pyrophosphorylase [EC:2.7.7.23]
E        K00012  UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
E        K08678  UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35]
E        K00966  GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
E        K00971  manC, cpsB; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
B
B  <b>Environmental information processing</b>
C    Two-component regulatory system
D      M00434  PhoR-PhoB (phosphate starvation response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07636  phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
E        K07657  phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
E        K07658  phoB1, phoP; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
D      M00443  SenX3-RegX3 (phosphate starvation response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07768  senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
E        K07776  regX3; two-component system, OmpR family, response regulator RegX3
D      M00444  PhoQ-PhoP (magnesium transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07637  phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
E        K07660  phoP; two-component system, OmpR family, response regulator PhoP
D      M00445  EnvZ-OmpR (osmotic stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07638  envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
E        K07659  ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
D      M00446  RstB-RstA two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07639  rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
E        K07661  rstA; two-component system, OmpR family, response regulator RstA
D      M00447  CpxA-CpxR (envelope stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07640  cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
E        K07662  cpxR; two-component system, OmpR family, response regulator CpxR
D      M00448  CssS-CssR (secretion stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07650  cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
E        K07770  cssR; two-component system, OmpR family, response regulator CssR
D      M00449  CreC-CreB (phosphate regulation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07641  creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
E        K07663  creB; two-component system, OmpR family, catabolic regulation response regulator CreB
D      M00450  BaeS-BaeR (envelope stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07642  baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
E        K07664  baeR; two-component system, OmpR family, response regulator BaeR
D      M00451  BasS-BasR (antimicrobial peptide resistance) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07643  basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
E        K07771  basR; two-component system, OmpR family, response regulator BasR
D      M00452  CusS-CusR (copper tolerance) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07644  cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
E        K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
D      M00453  QseC-QseB (quorum sensing) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07645  qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
E        K07666  qseB; two-component system, OmpR family, response regulator QseB
D      M00454  KdpD-KdpE (potassium transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07646  kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
E        K07667  kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D      M00455  TorS-TorR (trimethylamine N-oxide respiration) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07647  torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
E        K07772  torR; two-component system, OmpR family, torCAD operon response regulator TorR
D      M00456  ArcB-ArcA (anoxic redox control) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07648  arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
E        K07773  arcA; two-component system, OmpR family, aerobic respiration control protein ArcA
D      M00457  TctE-TctD (tricarboxylic acid transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07649  tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
E        K07774  tctD; two-component system, OmpR family, response regulator TctD
D      M00458  ResE-ResD (aerobic and anaerobic respiration) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07651  resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
E        K07775  resD; two-component system, OmpR family, response regulator ResD
D      M00459  VicK-VicR (cell wall metabolism) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07652  vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
E        K07668  vicR; two-component system, OmpR family, response regulator VicR
D      M00460  MprB-MprA (maintenance of persistent infection) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07653  mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
E        K07669  mprA; two-component system, OmpR family, response regulator MprA
D      M00461  MtrB-MtrA (osmotic stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07654  mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
E        K07670  mtrA; two-component system, OmpR family, response regulator MtrA
D      M00462  PrrB-PrrA (intracellular multiplication) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07655  prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
E        K07671  prrA; two-component system, OmpR family, response regulator PrrA
D      M00463  TrcS-TrcR two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07656  trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
E        K07672  trcR; two-component system, OmpR family, response regulator TrcR
D      M00464  NrsS-NrsR (nickel tolerance) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11328  nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and/or redox sensor kinase NrsS [EC:2.7.13.3]
E        K11330  nrsR, rppA; two-component system, OmpR family, Ni(II)-responsive and/or redox-responsive regulator NrsR
D      M00465  ManS-ManR (manganese homeostasis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11520  manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]
E        K11521  K11521, manR; two-component system, OmpR family, manganese sensing response regulator
D      M00466  NblS-NblR (photosynthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07769  nblS; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]
E        K11332  nblR; two-component system, OmpR family, response regulator NblR
D      M00467  SasA-RpaAB (circadian timing mediating) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K08479  sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]
E        K10697  rpaA; two-component system, OmpR family, response regulator RpaA
E        K11329  rpaB; two-component system, OmpR family, response regulator RpaB
D      M00468  SaeS-SaeR (staphylococcal virulence regulation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K10681  saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
E        K10682  saeR; two-component system, OmpR family, response regulator SaeR
D      M00469  BceS-BceR (bacitracin transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11629  bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
E        K11630  bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR
D      M00470  YxdK-YxdJ (antimicrobial peptide response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11633  yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
E        K11634  yxdJ; two-component system, OmpR family, response regulator YxdJ
D      M00471  NarX-NarL (nitrate respiration) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07673  narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
E        K07684  narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
D      M00472  NarQ-NarP (nitrate respiration) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07674  narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
E        K07685  narP; two-component system, NarL family, nitrate/nitrite response regulator NarP
D      M00473  UhpB-UhpA (hexose phosphates uptake) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07675  uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
E        K07686  uhpA; two-component system, NarL family, uhpT operon response regulator UhpA
D      M00474  RcsC-RcsD-RcsB (capsule synthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07677  rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
E        K07676  rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
E        K07687  rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
D      M00475  BarA-UvrY (central carbon metabolism) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07678  barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
E        K07689  uvrY; two-component system, NarL family, invasion response regulator UvrY
D      M00476  ComP-ComA (competence) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07680  comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
E        K07691  comA; two-component system, NarL family, competent response regulator ComA
D      M00477  EvgS-EvgA (acid and drug tolerance) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07679  evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
E        K07690  evgA, bvgA; two-component system, NarL family, response regulator EvgA
D      M00478  DegS-DegU (multicellular behavior control) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07777  degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
E        K07692  degU; two-component system, NarL family, response regulator DegU
D      M00479  DesK-DesR (membrane lipid fluidity regulation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07778  desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
E        K07693  desR; two-component system, NarL family, response regulator DesR
D      M00480  VraS-VraR (cell-wall peptidoglycan synthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07681  vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]
E        K07694  vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR
D      M00481  LiaS-LiaR (cell wall stress response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11617  liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
E        K11618  liaR; two-component system, NarL family, response regulator LiaR
D      M00482  DevS-DevR (redox response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07682  devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]
E        K07695  devR; two-component system, NarL family, response regulator DevR
D      M00483  NreB-NreC (dissimilatory nitrate/nitrite reduction) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07683  nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
E        K07696  nreC; two-component system, NarL family, response regulator NreC
D      M00484  YdfH-YdfI two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11623  ydfH; two-component system, NarL family, sensor histidine kinase YdfH [EC:2.7.13.3]
E        K11624  ydfI; two-component system, NarL family, response regulator YdfI
D      M00485  KinABCDE-Spo0FA (sporulation control) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K02491  kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
E        K07697  kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
E        K07698  kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
E        K13532  kinD; two-component system, sporulation sensor kinase D [EC:2.7.13.3]
E        K13533  kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
E        K02490  spo0F; two-component system, response regulator, stage 0 sporulation protein F
E        K07699  spo0A; two-component system, response regulator, stage 0 sporulation protein A
D      M00486  CitA-CitB (citrate fermentation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07700  dpiB, citA; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
E        K07702  dpiA, citB; two-component system, CitB family, response regulator CitB
D      M00487  CitS-CitT (magnesium-citrate transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11637  citS; two-component system, CitB family, sensor histidine kinase CitS [EC:2.7.13.3]
E        K11638  K11638, citT; two-component system, CitB family, response regulator CitT
D      M00488  DcuS-DcuR (aerobic C4-dicarboxylate metabolism) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07701  dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
E        K07703  dcuR; two-component system, CitB family, response regulator DcuR
D      M00489  DctS-DctR (C4-dicarboxylate transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11691  K11691, dctS; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]
E        K11692  K11692, dctR; two-component system, CitB family, response regulator DctR
D      M00490  MalK-MalR (malate transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11614  yufL, malK; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
E        K11615  malR; two-component system, CitB family, response regulator MalR
D      M00492  LytS-LytR (autolysis and cell wall metabolism) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07704  lytS; two-component system, LytT family, sensor histidine kinase LytS [EC:2.7.13.3]
E        K07705  lytT, lytR; two-component system, LytT family, response regulator LytT
D      M00493  AlgZ-AlgR (alginate production) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K08082  algZ; two-component system, LytT family, sensor histidine kinase AlgZ [EC:2.7.13.3]
E        K08083  algR; two-component system, LytT family, response regulator AlgR
D      M00494  NatK-NatR (sodium extrusion) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11640  natK; two-component system, LytT family, sensor histidine kinase NatK [EC:2.7.13.3]
E        K11641  natR; two-component system, LytT family, response regulator NatR
D      M00495  AgrC-AgrA (exoprotein synthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07706  agrC; two-component system, AgrA family, sensor histidine kinase AgrC [EC:2.7.13.-]
E        K07707  agrA; two-component system, AgrA family, response regulator AgrA
D      M00496  ComD-ComE (competence) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K12294  comD; two-component system, AgrA family, sensor histidine kinase ComD [EC:2.7.13.-]
E        K12295  comE; two-component system, AgrA family, response regulator ComE
D      M00497  GlnL-GlnG (nitrogen regulation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07708  glnL, ntrB; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
E        K07712  glnG, ntrC; two-component system, NtrC family, nitrogen regulation response regulator GlnG
D      M00498  NtrY-NtrX (nitrogen regulation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K13598  ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
E        K13599  ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D      M00499  HydH-HydG (metal tolerance) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07709  hydH, zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
E        K07713  hydG, zraR; two-component system, NtrC family, response regulator HydG
D      M00500  AtoS-AtoC (complexed poly-(R)-3-hydroxybutyrate biosynthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07710  atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
E        K07714  atoC; two-component system, NtrC family, response regulator AtoC
D      M00501  PilS-PilR (type 4 fimbriae synthesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K02668  pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
E        K02667  pilR; two-component system, NtrC family, response regulator PilR
D      M00502  GlrK-GlrR (amino sugar metabolism) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07711  glrK, qseE; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
E        K07715  glrR, qseF; two-component system, NtrC family, response regulator GlrR
D      M00503  PgtB-PgtA (phosphoglycerate transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K08475  pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
E        K08476  pgtA; two-component system, NtrC family, phosphoglycerate transport system response regulator PgtA
D      M00504  DctB-DctD (C4-dicarboxylate transport) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K10125  dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
E        K10126  dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
D      M00505  KinB-AlgB (alginate production) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11383  kinB1, kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
E        K11384  algB; two-component system, NtrC family, response regulator AlgB
D      M00506  CheA-CheYBV (chemotaxis) two-component regulatory system [PATH:map02020 map02030] [BR:ko02022 ko02030 ko02035]
E        K03407  cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
E        K03413  cheY; two-component system, chemotaxis family, response regulator CheY
E        K03412  cheB; two-component system, chemotaxis family, response regulator CheB [EC:3.1.1.61]
E        K13924  cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
E        K03415  cheV; two-component system, chemotaxis family, response regulator CheV
D      M00507  ChpA-ChpB/PilGH (chemosensory) two-component regulatory system [PATH:map02020] [BR:ko02022 ko02035]
E        K06596  chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
E        K02487  pilL; type IV pili sensor histidine kinase and response regulator
E        K02657  pilG; twitching motility two-component system response regulator PilG
E        K02658  pilH; twitching motility two-component system response regulator PilH
E        K06597  chpB; chemosensory pili system protein ChpB (putative protein-glutamate methylesterase)
D      M00508  PixL-PixGH (positive phototaxis) two-component regulatory system [PATH:map02020] [BR:ko02022 ko02035]
E        K11526  pixL; two-component system, chemotaxis family, sensor histidine kinase and response regulator PixL
E        K11522  pixG; two-component system, chemotaxis family, response regulator PixG
E        K11523  pixH; two-component system, chemotaxis family, response regulator PixH
D      M00509  WspE-WspRF (chemosensory) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K13490  wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
E        K11444  wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
E        K13491  wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
D      M00510  Cph1-Rcp1 (light response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K11354  cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
E        K11355  rcp1; two-component system, chemotaxis family, response regulator Rcp1
D      M00511  PleC-PleD (cell fate control) two-component regulatory system [PATH:map02020 map04112] [BR:ko02022]
E        K07716  pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
E        K11357  divJ; two-component system, cell cycle sensor histidine kinase DivJ [EC:2.7.13.3]
E        K02489  pleC1; two-component system, cell cycle sensor kinase and response regulator [EC:2.7.13.3]
E        K02488  pleD; two-component system, cell cycle response regulator
E        K11443  divK; two-component system, cell cycle response regulator DivK
E        K13591  popA; two-component system, cell cycle response regulator PopA
D      M00512  CckA-CtrA/CpdR (cell cycle control) two-component regulatory system [PATH:map02020 map04112] [BR:ko02022]
E        K13587  cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
E        K13584  ctrA; two-component system, cell cycle response regulator CtrA
E        K13589  cpdR; two-component system, cell cycle response regulator CpdR
D      M00513  LuxQN/CqsS-LuxU-LuxO (quorum sensing) two-component regulatory system [PATH:map02020 map05111] [BR:ko02022]
E        K10909  luxQ; two-component system, autoinducer 2 sensor kinase/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]
E        K10916  cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
E        K10911  luxU; two-component system, phosphorelay protein LuxU
E        K10912  luxO; two-component system, repressor protein LuxO
D      M00514  TtrS-TtrR (tetrathionate respiration) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K13040  ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
E        K13041  ttrR; two-component system, LuxR family, response regulator TtrR
D      M00515  FlrB-FlrC (polar flagellar synthesis) two-component regulatory system [PATH:map02020 map05111] [BR:ko02022]
E        K10942  flrB, fleS; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
E        K10943  flrC, fleR; two component system, response regulator FlrC
D      M00516  SLN1-YPD1-SSK1/SKN7 (osmosensing) two-component regulatory system [PATH:map02020 map04011] [BR:ko02022]
E        K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
E        K11232  YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
E        K11233  SSK1; osomolarity two-component system, response regulator SSK1
E        K15859  SKN7; osomolarity two-component system, response regulator SKN7
D      M00517  RpfC-RpfG (cell-to-cell signaling) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K10715  rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
E        K13815  rpfG; two-component system, response regulator RpfG
D      M00518  GlnK-GlnL (glutamine utilization) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07717  ycbA, glnK; two-component system, sensor histidine kinase YcbA [EC:2.7.13.3]
E        K07719  ycbB, glnL; two-component system, response regulator YcbB
D      M00519  YesM-YesN two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K07718  yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
E        K07720  yesN; two-component system, response regulator YesN
D      M00520  ChvG-ChvI (acidity sensing) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K14980  chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
E        K14981  chvI; two-component system, OmpR family, response regulator ChvI
D      M00521  CiaH-CiaR (stress resistance and pathogenesis) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K14982  ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
E        K14983  ciaR; two-component system, OmpR family, response regulator CiaR
D      M00522  SalK-SalR two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K14988  salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
E        K14989  salR; two-component system, NarL family, secretion system response regulator SalR
D      M00523  RegB-RegA (redox response) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K15011  regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
E        K15012  regA, regR, actR; two-component system, response regulator RegA
D      M00524  FixL-FixJ (nitrogen fixation) two-component regulatory system [PATH:map02020] [BR:ko02022]
E        K14986  fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
E        K14987  fixJ; two-component system, LuxR family, response regulator FixJ
#
A<b>Signature module</b>
B
B  <b>Genotypic signature</b>
C    Metabolic capacity
D      M00557  Methanogenesis [PATH:map00680]
E        K00399  mcrA; methyl-coenzyme M reductase alpha subunit [EC:2.8.4.1]
E        K00401  mcrB; methyl-coenzyme M reductase beta subunit [EC:2.8.4.1]
E        K00402  mcrG; methyl-coenzyme M reductase gamma subunit [EC:2.8.4.1]
D      M00558  Methane oxidation by pMMO [PATH:map00680]
E        K16154  pmoA; methane monooxygenase subunit A [EC:1.14.13.25]
E        K16155  pmoB; methane monooxygenase subunit B [EC:1.14.13.25]
E        K16156  pmoC; methane monooxygenase subunit C [EC:1.14.13.25]
D      M00559  Methane oxidation by sMMO [PATH:map00680]
E        K16157  mmoX; methane monooxygenase component A alpha chain [EC:1.14.13.25]
E        K16158  mmoY; methane monooxygenase component A beta chain [EC:1.14.13.25]
E        K16159  mmoZ; methane monooxygenase component A gamma chain [EC:1.14.13.25]
E        K16160  mmoB; methane monooxygenase regulatory protein B
E        K16161  mmoC; methane monooxygenase component C [EC:1.14.13.25]
D      M00560  Ammonia oxidation [PATH:map00910]
E        K10944  amoA; ammonia monooxygenase subunit A [EC:1.14.99.39]
E        K10945  amoB; ammonia monooxygenase subunit B
E        K10946  amoC; ammonia monooxygenase subunit C
C    Pathogenicity
D      M00363  EHEC pathogenicity signature, Shiga toxin [PATH:map05130 map05131]
E        K11006  stxA; shiga toxin subunit A
E        K11007  stxB; shiga toxin subunit B
D      M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors [PATH:map05130]
E        K03221  yscF; type III secretion protein SctF
E        K03219  yscC; type III secretion protein SctC
E        K03222  yscJ; type III secretion protein SctJ
E        K03226  yscR; type III secretion protein SctR
E        K03227  yscS; type III secretion protein SctS
E        K03228  yscT; type III secretion protein SctT
E        K03229  yscU; type III secretion protein SctU
E        K03230  yscV; type III secretion protein SctV
E        K03224  yscN; ATP synthase in type III secretion protein SctN [EC:3.6.3.14]
E        K03225  yscQ; type III secretion protein SctQ
E        K12784  tir; translocated intimin receptor
E        K12787  map; LEE-encoded effector Map
E        K12785  espG, virA; LEE-encoded effector EspG
E        K12786  espF; LEE-encoded effector EspF
E        K12788  espH; LEE-encoded effector EspH
E        K16041  nleA; non-LEE-encoded effector NleA
E        K16042  nleH; non-LEE-encoded effector NleH
D      M00574  Pertussis pathogenicity signature 1, pertussis toxin [PATH:map05133]
E        K11023  ptxA; pertussis toxin subunit 1 [EC:2.4.2.-]
E        K11024  ptxB; pertussis toxin subunit 2
E        K11025  ptxC; pertussis toxin subunit 3
E        K11026  ptxD; pertussis toxin subunit 4
E        K11027  ptxE; pertussis toxin subunit 5
D      M00575  Pertussis pathogenicity signature 2, T1SS [PATH:map05133]
E        K11029  cyaA; anthrax edema toxin adenylate cyclase [EC:4.6.1.1]
E        K11004  hlyB, cyaB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
E        K07389  cyaC, hlyC, rtxC; cytolysin-activating lysine-acyltransferase [EC:2.3.1.-]
E        K11003  hlyD, cyaD; hemolysin D
E        K12340  tolC; outer membrane channel protein
D      M00564  Helicobacter pylori pathogenicity signature, cagA pathogenicity island [PATH:map05120]
E        K15842  cagA; cytotoxicity-associated immunodominant antigen
E        K12086  cag1; cag pathogenicity island protein 1
E        K12087  cag2; cag pathogenicity island protein 2
E        K12088  cag3; cag pathogenicity island protein 3
E        K12089  cag4; cag pathogenicity island protein 4
E        K12090  cag5; cag pathogenicity island protein 5
E        K03196  virB11, lvhB11; type IV secretion system protein VirB11
E        K12091  cag6; cag pathogenicity island protein 6
E        K12092  cag7; cag pathogenicity island protein 7
E        K12093  cag8; cag pathogenicity island protein 8
E        K12094  cag9; cag pathogenicity island protein 9
E        K12095  cag10; cag pathogenicity island protein 10
E        K12096  cag11; cag pathogenicity island protein 11
E        K12097  cag12; cag pathogenicity island protein 12
E        K12098  cag13; cag pathogenicity island protein 13
E        K12099  cag14; cag pathogenicity island protein 14
E        K12100  cag15; cag pathogenicity island protein 15
E        K12101  cag16; cag pathogenicity island protein 16
E        K12102  cag17; cag pathogenicity island protein 17
E        K12103  cag18; cag pathogenicity island protein 18
E        K12104  cag19; cag pathogenicity island protein 19
E        K12105  cag20; cag pathogenicity island protein 20
E        K12106  cag21; cag pathogenicity island protein 21
E        K12107  cag22; cag pathogenicity island protein 22
E        K12108  cag23; cag pathogenicity island protein 23
E        K12109  cag24; cag pathogenicity island protein 24
E        K12110  cag25; cag pathogenicity island protein 25
!
#<hr>
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#Last updated: May 17, 2013
