+C Peptidase
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Peptidases
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AAspartic Peptidases
B Family A1: pepsin family
C K06002 PGA; pepsin A [EC:3.4.23.1]
C K01377 PGC; gastricsin [EC:3.4.23.3]
C K04521 BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
C K07747 BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
C K01378 CYM; chymosin [EC:3.4.23.4]
C K01380 REN; renin [EC:3.4.23.15]
C K01379 CTSD; cathepsin D [EC:3.4.23.5]
C K01382 CTSE; cathepsin E [EC:3.4.23.34]
C K01383 E3.4.23.35; barrierpepsin [EC:3.4.23.35]
C K06004 E3.4.23.18; aspergillopepsin I [EC:3.4.23.18]
C K01381 E3.4.23.25; saccharopepsin [EC:3.4.23.25]
C K08245 E3.4.23.40; phytepsin [EC:3.4.23.40]
C K06007 E3.4.23.38; plasmepsin I [EC:3.4.23.38]
C K06008 E3.4.23.39; plasmepsin II [EC:3.4.23.39]
C K06009 E3.4.23.41; yapsin 1 [EC:3.4.23.41]
C K06005 SAP; candidapepsin [EC:3.4.23.24]
C K08565 NAPSA; napsin-A [EC:3.4.23.-]
B Family A5: thermopsin family
C K01385 E3.4.23.42; thermopsin [EC:3.4.23.42]
B Family A8: signal peptidase II family
C K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
C K04505 PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
C K04522 PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
C K06060 PSENN; presenilin, other
C K09595 HM13; minor histocompatibility antigen H13 [EC:3.4.23.-]
C K09596 SPPL2A; signal peptide peptidase-like 2A [EC:3.4.23.-]
C K09597 SPPL2B; signal peptide peptidase-like 2B [EC:3.4.23.-]
C K14212 SPPL2C, IMP5; signal peptide peptidase-like 2C [EC:3.4.23.-]
C K09598 SPPL3; signal peptide peptidase-like 3 [EC:3.4.23.-]
B Family A24: type IV prepilin peptidase family
C K02654 pilD, pppA; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]
C K10966 tcpJ; toxin co-regulated pilus biosynthesis protein J [EC:3.4.23.43 2.1.1.-]
C K02506 hofD, hopD; leader peptidase HopD [EC:3.4.23.43]
C K07991 flaK-A, flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
B Family A25: gpr protease family
C K06012 gpr; spore protease [EC:3.4.24.78]
B Family A26: omptin family
C K01355 ompT; omptin [EC:3.4.23.49]
C K08566 pla; plasminogen activator [EC:3.4.23.48]
C K08477 pgtE; outer membrane protease E [EC:3.4.21.-]
C K13520 icsP, sopA; outer membrane protease [EC:3.4.23.-]
B Family A31: HybD endopeptidase family
C K03605 hyaD; hydrogenase 1 maturation protease [EC:3.4.24.-]
C K08567 hybD; hydrogenase 2 maturation protease [EC:3.4.24.-]
C K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]
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ACysteine Peptidases
B Family C1: papain family
C K06000 E3.4.22.2; papain [EC:3.4.22.2]
C K16292 CEP, CYSEP; KDEL-tailed cysteine endopeptidase [EC:3.4.22.-]
C K01363 CTSB; cathepsin B [EC:3.4.22.1]
C K01275 CTSC; cathepsin C [EC:3.4.14.1]
C K01373 CTSF; cathepsin F [EC:3.4.22.41]
C K01366 CTSH; cathepsin H [EC:3.4.22.16]
C K01371 CTSK; cathepsin K [EC:3.4.22.38]
C K01365 CTSL; cathepsin L [EC:3.4.22.15]
C K09600 CTSM; cathepsin M [EC:3.4.22.-]
C K01374 CTSO; cathepsin O [EC:3.4.22.42]
C K09599 CTSP; cathepsin P [EC:3.4.22.-]
C K09601 CTSR; cathepsin R [EC:3.4.22.-]
C K01368 CTSS; cathepsin S [EC:3.4.22.27]
C K01375 CTSL2, CTSV; cathepsin V [EC:3.4.22.43]
C K08569 CTSW; cathepsin W [EC:3.4.22.-]
C K08568 CTSZ; cathepsin X [EC:3.4.18.1]
C K08570 EHCP; histolysain [EC:3.4.22.35]
C K13441 RCR3; cysteine protease
C K16290 XCP; xylem cysteine proteinase [EC:3.4.22.-]
C K08571 E3.4.22.51; cruzipain [EC:3.4.22.51]
C K13538 CPA; cysteine peptidase A [EC:3.4.22.-]
C K13537 CPB; cysteine peptidase B [EC:3.4.22.-]
C K08572 CPC; cysteine peptidase C [EC:3.4.22.-]
C K01372 E3.4.22.40, pepC; bleomycin hydrolase [EC:3.4.22.40]
B Family C2: calpain family
C K01367 CAPN1; calpain-1 [EC:3.4.22.52]
C K03853 CAPN2; calpain-2 [EC:3.4.22.53]
C K08573 CAPN3; calpain-3 [EC:3.4.22.54]
C K08574 CAPN5; calpain-5 [EC:3.4.22.-]
C K08575 CAPN6; calpain-6 [EC:3.4.22.-]
C K08576 CAPN7; calpain-7 [EC:3.4.22.-]
C K08577 CAPN8; calpain-8 [EC:3.4.22.-]
C K08578 CAPN9; calpain-9 [EC:3.4.22.-]
C K08579 CAPN10; calpain-10 [EC:3.4.22.-]
C K08580 CAPN11; calpain-11 [EC:3.4.22.-]
C K04740 CAPN12; calpain-12 [EC:3.4.22.-]
C K08581 CAPN13; calpain-13 [EC:3.4.22.-]
C K13442 CAPN14; calpain-14 [EC:3.4.22.-]
C K08582 CAPN15; calpain-15 [EC:3.4.22.-]
C K08583 CAPNS1, CAPN4; calpain, small subunit 1
C K08584 CAPNS2; calpain, small subunit 2
C K08585 CAPNN; calpain, invertebrate [EC:3.4.22.-]
C K08586 tpr; thiol protease [EC:3.4.22.-]
B Family C10: streptopain family
C K01364 speB; streptopain [EC:3.4.22.10]
B Family C11: clostripain family
C K08587 cloSI; clostripain [EC:3.4.22.8]
B Family C12: ubiquitin C-terminal hydrolase family
C K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
C K05609 UCHL3, YUH1; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C K08588 BAP1, UCHL2; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
C K05610 UCHL5, UCH37; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
B Family C13: legumain family
C K01369 LGMN; legumain [EC:3.4.22.34]
B Family C14: caspase family
C K01370 CASP1; caspase 1 [EC:3.4.22.36]
C K02186 CASP2; caspase 2 [EC:3.4.22.55]
C K02187 CASP3; caspase 3 [EC:3.4.22.56]
C K04394 CASP4; caspase 4 [EC:3.4.22.57]
C K04395 CASP5; caspase 5 [EC:3.4.22.58]
C K04396 CASP6; caspase 6 [EC:3.4.22.59]
C K04397 CASP7; caspase 7 [EC:3.4.22.60]
C K04398 CASP8; caspase 8 [EC:3.4.22.61]
C K04399 CASP9; caspase 9 [EC:3.4.22.62]
C K04400 CASP10; caspase 10 [EC:3.4.22.63]
C K12808 CASP11; caspase 11 [EC:3.4.22.64]
C K04741 CASP12; caspase 12 [EC:3.4.22.-]
C K04401 CASP14; caspase 14 [EC:3.4.22.-]
C K13521 CASP15; caspase 15
C K04489 CASPN; caspase invertebrate, apoptosis-related cysteine protease [EC:3.4.22.-]
C K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
C K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
B Family C15: pyroglutamyl peptidase I family
C K01304 E3.4.19.3, pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C19: ubiquitin-specific protease family
C K11836 USP5_13, UBP14; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.1.2.15]
C K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
C K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
C K11835 USP4_11_15, UBP12; ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
C K11839 USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
C K11833 USP2_21; ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
C K11843 USP14, UBP6; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.1.2.15]
C K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
C K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.1.2.15]
C K11841 USP10, UBP3; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]
C K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
C K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15]
C K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.1.2.15]
C K11845 USP17, DUB3; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.1.2.15]
C K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.1.2.15]
C K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15]
C K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.1.2.15]
C K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.1.2.15]
C K11366 USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.1.2.15]
C K11849 USP25_28, UBP2; ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.1.2.15]
C K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.1.2.15]
C K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.1.2.15]
C K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.1.2.15]
C K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.1.2.15]
C K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.1.2.15]
C K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.1.2.15]
C K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.1.2.15]
C K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.1.2.15]
C K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.1.2.15]
C K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.1.2.15]
C K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]
C K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.1.2.15]
C K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.1.2.15]
C K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.1.2.15]
C K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.1.2.15]
C K01072 E3.1.2.15; ubiquitin thiolesterase [EC:3.1.2.15]
B Family C25: gingipain family
C K08589 E3.4.22.37; gingipain R [EC:3.4.22.37]
B Family C26: gamma-glutamyl hydrolase family
C K01307 GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
C K01951 E6.3.5.2, guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C K01948 CPS1; carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
C K11540 CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
C K09473 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
C K07010 K07010; putative glutamine amidotransferase
B Family C40
C K13694 spr; lipoprotein Spr
C K13695 nlpC; probable lipoprotein NlpC
B Family C44
C K00764 purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
C K00820 E2.6.1.16, glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
C K01953 asnB, ASNS; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
C K10852 E2.3.1.164; isopenicillin-N N-acyltransferase [EC:2.3.1.164]
B Family C46: hedgehog family
C K06224 HH; hedgehog
C K11988 SHH; sonic hedgehog
C K11989 IHH; indian hedgehog
C K11990 DHH; desert hedgehog
B Family C47: staphopain family
C K08258 sspB2, sspP, scpA; staphopain A [EC:3.4.22.48]
C K13715 sspB1; staphopain B [EC:3.4.22.-]
B Family C48: Ulp1 endopeptidase family
C K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C K03345 SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C K08597 SENP8, NEDP1, DEN1; sentrin-specific protease 8 [EC:3.4.22.68]
B Family C50: separase family
C K02365 ESP1; separase [EC:3.4.22.49]
B Family C54: Aut2 peptidase family
C K08342 ATG4; autophagy-related protein 4 [EC:3.4.22.-]
B Family C55: YopJ protease family
C K08598 yopJ; YopJ protease family
B Family C56: PfpI endopeptidase family
C K05520 pfpI; protease I [EC:3.2.-.-]
C K05687 PARK7; protein DJ-1
C K03152 thiJ; 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis
B Family C58
C K08599 yopT; YopT peptidase [EC:3.4.22.-]
C K13440 avrPphB; cysteine protease avirulence protein AvrPphB [EC:3.4.22.-]
B Family C59
C K01434 E3.5.1.11; penicillin amidase [EC:3.5.1.11]
B Family C60
C K07284 srtA; sortase A [EC:3.4.22.70]
C K08600 srtB; sortase B [EC:3.4.22.70]
B Family C64
C K11860 OTUD7; OTU domain-containing protein 7 [EC:3.-.-.-]
C K11859 TNFAIP3, A20; tumor necrosis factor, alpha-induced protein 3 [EC:3.-.-.-]
C K11862 ZRANB1, TRABID; ubiquitin thioesterase ZRANB1 [EC:3.1.2.-]
C K11861 VCPIP1, VCIP135; deubiquitinating protein VCIP135 [EC:3.4.22.-]
B Family C65
C K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.-.-]
C K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.-.-]
B Family C67
C K08601 CYLD, USLP2; ubiquitin thioesterase CYLD [EC:3.1.2.15]
B Family C69
C K08659 pepDA, pepDB; dipeptidase [EC:3.4.-.-]
C K14358 SCRN; secernin
B Family C70
C K13439 avrRpt2; cysteine protease avirulence protein AvrRpt2 [EC:3.4.22.-]
B Family C75
C K07813 agrB; accessory gene regulator B
B Family C82
C K16291 erfK; L,D-transpeptidase
B Family C85: DUBA deubiquitinylating enzyme
C K13716 OTUD1; OTU domain-containing protein 1
C K13717 OTUD3; OTU domain-containing protein 3
C K13718 OTUD4; OTU domain-containing protein 4
C K12655 OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.1.2.15]
B Family C86
C K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
C K15235 JOSD; josephin [EC:3.4.19.12]
B Family C88
C K13719 OTU1, YOD1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
B Family C89
C K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
C K13720 NAAA; N-acylethanolamine-hydrolyzing acid amidase [EC:3.5.1.-]
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AMetallo Peptidases
B Family M1
C K11140 ANPEP; aminopeptidase N [EC:3.4.11.2]
C K11141 ENPEP; glutamyl aminopeptidase [EC:3.4.11.7]
C K01254 E3.3.2.6, LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C K01256 pepN; aminopeptidase N [EC:3.4.11.2]
C K13721 APE2; aminopeptidase 2 [EC:3.4.11.-]
C K01306 TRHDE; pyroglutamyl-peptidase II [EC:3.4.19.6]
C K08776 NPEPPS; puromycin-sensitive aminopeptidase [EC:3.4.11.-]
C K01257 LNPEP; cystinyl aminopeptidase [EC:3.4.11.3]
C K01260 RNPEP; aminopeptidase B [EC:3.4.11.6]
C K09604 ARTS1; adipocyte-derived leucine aminopeptidase [EC:3.4.11.-]
C K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-]
C K09605 RNPEPL1; arginyl aminopeptidase-like 1 [EC:3.4.11.-]
C K13723 ERAP2; endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]
C K13724 AQPEP; aminopeptidase Q [EC:3.4.11.-]
C K09606 C9ORF3; aminopeptidase O [EC:3.4.11.-]
C K13725 PFAM1; M1-family aminopeptidase [EC:3.4.11.-]
C K03128 TAF2; transcription initiation factor TFIID subunit 2
B Family M2
C K01283 E3.4.15.1, ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
C K09708 ACEH, ACE2; angiotensin-converting enzyme 2 [EC:3.4.17.23]
B Family M3
C K01392 THOP1; thimet oligopeptidase [EC:3.4.24.15]
C K01393 NLN; neurolysin [EC:3.4.24.16]
C K01405 PRD1; saccharolysin [EC:3.4.24.37]
C K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
C K01410 E3.4.24.59, MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
C K13726 MEPB; metallopeptidase MepB [EC:3.4.24.-]
C K08602 pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]
B Family M4: thermolysin family
C K08603 E3.4.24.27; thermolysin [EC:3.4.24.27]
C K08604 E3.4.24.25; vibriolysin [EC:3.4.24.25]
C K01399 lasB; pseudolysin [EC:3.4.24.26]
C K08605 E3.4.24.30; coccolysin [EC:3.4.24.30]
C K01401 aur; aureolysin [EC:3.4.24.29]
C K08777 nprB; neutral peptidase B [EC:3.4.24.-]
C K01400 E3.4.24.28; bacillolysin [EC:3.4.24.28]
B Family M6: immune inhibitor A family
C K09607 ina; immune inhibitor A [EC:3.4.24.-]
B Family M7: snapalysin family
C K01416 E3.4.24.77; snapalysin [EC:3.4.24.77]
B Family M8: leishmanolysin family
C K01404 GP63; leishmanolysin [EC:3.4.24.36]
C K13539 LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
B Family M9
C K01387 colA; microbial collagenase [EC:3.4.24.3]
B Family M10
C K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
C K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
C K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
C K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
C K01402 MMP8; matrix metalloproteinase-8 (neutrophil collagenase) [EC:3.4.24.34]
C K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
C K01396 MMP10; matrix metalloproteinase-10 (stromelysin 2) [EC:3.4.24.22]
C K07993 MMP11; matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-]
C K01413 MMP12; matrix metalloproteinase-12 (macrophage elastase) [EC:3.4.24.65]
C K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
C K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
C K07995 MMP15; matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]
C K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
C K07997 MMP17; matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-]
C K07998 MMP19, MMP18; matrix metalloproteinase-19 (RASI) [EC:3.4.24.-]
C K07999 MMP20; matrix metalloproteinase-20 (enamelysin) [EC:3.4.24.-]
C K08000 MMP21; matrix metalloproteinase-21 [EC:3.4.24.-]
C K08001 MMP23; matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-]
C K08002 MMP24; matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-]
C K08003 MMP25; matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]
C K08004 MMP26; matrix metalloproteinase-26 (matrilysin-2, endometase) [EC:3.4.24.-]
C K08005 MMP27; matrix metalloproteinase-27 [EC:3.4.24.-]
C K08006 MMP28; matrix metalloproteinase-28 (epilysin) [EC:3.4.24.-]
C K01406 E3.4.24.40; serralysin [EC:3.4.24.40]
B Family M12: astacin/adamalysin family
C K08076 E3.4.24.21; astacin [EC:3.4.24.21]
C K08778 ASTL; astacin-like metalloendopeptidase [EC:3.4.-.-]
C K01395 MEP1A; meprin A, alpha [EC:3.4.24.18]
C K08606 MEP1B; meprin A, beta [EC:3.4.24.18]
C K05502 BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
C K13045 tld; tolloid [EC:3.4.24.-]
C K13046 tok; tolkin [EC:3.4.24.-]
C K09608 TLL1; tolloid-like protein 1 [EC:3.4.24.-]
C K13047 TLL2; tolloid-like protein 2 [EC:3.4.24.-]
C K08607 ADAM1; disintegrin and metalloproteinase domain-containing protein 1 [EC:3.4.24.-]
C K06833 ADAM2; disintegrin and metalloproteinase domain-containing protein 2 [EC:3.4.24.-]
C K16071 ADAM7; disintegrin and metalloproteinase domain-containing protein 7 [EC:3.4.24.-]
C K06540 ADAM8; disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]
C K06834 ADAM9; disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-]
C K06704 ADAM10; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
C K16067 ADAM11; disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-]
C K06835 ADAM12; disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-]
C K06836 ADAM15; disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]
C K06059 ADAM17, TACE; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
C K16909 ADAM18; disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-]
C K08608 ADAM19; disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-]
C K08609 ADAM20; disintegrin and metalloproteinase domain-containing protein 20 [EC:3.4.24.-]
C K08610 ADAM21; disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-]
C K16068 ADAM22; disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-]
C K06837 ADAM23; disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-]
C K08611 ADAM24; disintegrin and metalloproteinase domain-containing protein 24 [EC:3.4.24.-]
C K08612 ADAM25; disintegrin and metalloproteinase domain-containing protein 25 [EC:3.4.24.-]
C K08613 ADAM26; disintegrin and metalloproteinase domain-containing protein 26 [EC:3.4.24.-]
C K08614 ADAM28; disintegrin and metalloproteinase domain-containing protein 28 [EC:3.4.24.-]
C K16069 ADAM29; disintegrin and metalloproteinase domain-containing protein 29 [EC:3.4.24.-]
C K08615 ADAM30; disintegrin and metalloproteinase domain-containing protein 30 [EC:3.4.24.-]
C K16070 ADAM32; disintegrin and metalloproteinase domain-containing protein 32 [EC:3.4.24.-]
C K08616 ADAM33; disintegrin and metalloproteinase domain-containing protein 33 [EC:3.4.24.-]
C K08617 ADAMTS1; a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-]
C K08618 ADAMTS2; a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14]
C K08619 ADAMTS3; a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-]
C K07764 ADAMTS4; a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82]
C K08620 ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-]
C K08621 ADAMTS6; a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]
C K08622 ADAMTS7; a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-]
C K08623 ADAMTS8; a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-]
C K08624 ADAMTS9; a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-]
C K08625 ADAMTS10; a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]
C K08626 ADAMTS12; a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-]
C K08627 ADAMTS13; a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.-]
C K08628 ADAMTS14; a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-]
C K08629 ADAMTS15; a disintegrin and metalloproteinase with thrombospondin motifs 15 [EC:3.4.24.-]
C K08630 ADAMTS16; a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-]
C K08631 ADAMTS17; a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]
C K08632 ADAMTS18; a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-]
C K08633 ADAMTS19; a disintegrin and metalloproteinase with thrombospondin motifs 19 [EC:3.4.24.-]
C K09609 ADAMTS20; a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-]
C K08634 ADAMDEC1; ADAM-like, decysin 1 [EC:3.4.24.-]
B Family M13: neprilysin family
C K01389 MME; neprilysin [EC:3.4.24.11]
C K01415 E3.4.24.71, ECE1, ECE2; endothelin-converting enzyme [EC:3.4.24.71]
C K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C K09610 ECEL1; endothelin-converting enzyme-like 1 [EC:3.4.24.-]
C K08635 MMEL1; membrane metallo-endopeptidase-like 1
C K06577 KEL; Kell blood group glycoprotein [EC:3.4.24.-]
C K08636 PHEX; phosphate-regulating neutral endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
C K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
C K08780 CPA3; carboxypeptidase A3 [EC:3.4.17.1]
C K08781 CPA5; carboxypeptidase A5 [EC:3.4.17.1]
C K08782 CPA6; carboxypeptidase A6 [EC:3.4.17.1]
C K01298 CPA2; carboxypeptidase A2 [EC:3.4.17.15]
C K08637 CPA4; carboxypeptidase A4 [EC:3.4.17.-]
C K01290 CPAN; carboxypeptidase A, invertebrate [EC:3.4.17.-]
C K01291 CPB1; carboxypeptidase B [EC:3.4.17.2]
C K01300 CPB2; carboxypeptidase B2 [EC:3.4.17.20]
C K08783 ECM14; extracellular matrix protein 14 [EC:3.4.17.-]
C K07752 CPD; carboxypeptidase D [EC:3.4.17.22]
C K01294 CPE; carboxypeptidase E [EC:3.4.17.10]
C K01296 CPM; carboxypeptidase M [EC:3.4.17.12]
C K01292 CPN1; carboxypeptidase N catalytic subunit [EC:3.4.17.3]
C K05996 cpt; carboxypeptidase T [EC:3.4.17.18]
C K08638 CPXM1; carboxypeptidase X1 [EC:3.4.17.-]
C K08639 CPXM2; carboxypeptidase X2
C K13022 CPZ; carboxypeptidase Z [EC:3.4.17.-]
C K01308 E3.4.19.11; g-D-glutamyl-meso-diaminopimelate peptidase [EC:3.4.19.11]
B Family M15
C K08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C K07260 vanY; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
C K08641 vanX; D-alanyl-D-alanine dipeptidase [EC:3.4.13.22]
B Family M16: pitrilysin family
C K01407 ptr; protease III [EC:3.4.24.55]
C K01408 IDE, ide; insulysin [EC:3.4.24.56]
C K01412 E3.4.24.64; mitochondrial processing peptidase [EC:3.4.24.64]
C K01411 NRD1; nardilysin [EC:3.4.24.61]
C K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
C K01255 CARP, pepA; leucyl aminopeptidase [EC:3.4.11.1]
C K07751 pepB; PepB aminopeptidase [EC:3.4.11.23]
C K09611 NPEPL1; probable aminopeptidase NPEPL1 [EC:3.4.11.-]
B Family M18
C K01268 E3.4.11.22, LAP4; aminopeptidase I [EC:3.4.11.22]
C K01267 E3.4.11.21, DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
B Family M19: membrane dipeptidase family
C K01273 E3.4.13.19, DPEP1; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C K01295 E3.4.17.11; glutamate carboxypeptidase [EC:3.4.17.11]
C K01293 E3.4.17.4; Gly-Xaa carboxypeptidase [EC:3.4.17.4]
C K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C K05604 CNDP1; beta-Ala-His dipeptidase [EC:3.4.13.20]
C K08660 CNDP2; cytosolic nonspecific dipeptidase [EC:3.4.13.18]
C K15428 DUG1; Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
C K14262 DUG2; di- and tripeptidase [EC:3.4.-.-]
C K01270 K01270, pepD; dipeptidase D [EC:3.4.13.-]
C K13048 CPS; carboxypeptidase Ss1 [EC:3.4.17.-]
C K13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]
C K02083 allC; allantoate deiminase [EC:3.5.3.9]
C K14664 ILR1; IAA-amino acid hydrolase [EC:3.5.1.-]
C K14677 ACY1; aminoacylase [EC:3.5.1.14]
C K05823 E3.5.1.47; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]
C K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
C K12940 abgA; aminobenzoyl-glutamate utilization protein A
C K12941 abgB; aminobenzoyl-glutamate utilization protein B
C K14665 amhX; amidohydrolase [EC:3.5.1.-]
C K01436 K01436; amidohydrolase [EC:3.5.1.-]
B Family M22
C K01409 gcp, QRI7, OSGEPL; O-sialoglycoprotein endopeptidase [EC:3.4.24.57]
C K15900 KAE1, OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein
C K15904 K15904; bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein [EC:2.7.11.1]
C K14742 yeaZ; hypothetical protease [EC:3.4.-.-]
B Family M23
C K08642 lasA; LasA protease [EC:3.4.24.-]
C K08259 lytM; lysostaphin [EC:3.4.24.75]
B Family M24
C K01265 E3.4.11.18, map; methionyl aminopeptidase [EC:3.4.11.18]
C K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C K14213 PEPD; Xaa-Pro dipeptidase [EC:3.4.13.9]
C K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
C K14208 XPNPEP2; Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]
C K08326 ypdF; aminopeptidase [EC:3.4.11.-]
B Family M26
C K01390 E3.4.24.13; IgA-specific metalloendopeptidase [EC:3.4.24.13]
C K08643 zmpB; zinc metalloprotease ZmpB [EC:3.4.24.-]
B Family M27
C K08644 tetX; tentoxilysin [EC:3.4.24.68]
C K06011 boNT; botulinum neurotoxin [EC:3.4.24.69]
B Family M28: aminopeptidase Y family
C K01264 E3.4.11.15, APE3; aminopeptidase Y [EC:3.4.11.15]
C K05994 E3.4.11.10; bacterial leucyl aminopeptidase [EC:3.4.11.10]
C K09612 iap; alkaline phosphatase isozyme conversion protein [EC:3.4.11.-]
C K14592 FOLH1; folate hydrolase 1 [EC:3.4.17.21]
C K01301 E3.4.17.21; glutamate carboxypeptidase II [EC:3.4.17.21]
B Family M32: carboxypeptidase Taq family
C K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
C K08645 lef; anthrax lethal toxin endopeptidase [EC:3.4.24.83]
B Family M35: deuterolysin family
C K08646 E3.4.24.20; peptidyl-Lys metalloendopeptidase [EC:3.4.24.20]
B Family M38: beta-aspartyl dipeptidase family
C K01305 iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]
C K11540 CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
B Family M41: FtsH endopeptidase family
C K03798 ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]
C K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
C K08955 YME1; ATP-dependent metalloprotease [EC:3.4.24.-]
C K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
C K01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7]
B Family M43: cytophagalysin familyv
C K07762 PAPPA; pappalysin-1 [EC:3.4.24.79]
C K08647 PAPPA2; pappalysin-2 [EC:3.4.24.-]
B Family M48: Ste24 endopeptidase family
C K06013 STE24; STE24 endopeptidase [EC:3.4.24.84]
C K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C K07387 K07387; putative metalloprotease [EC:3.4.24.-]
B Family M49: dipeptidyl-peptidase III family
C K01277 E3.4.14.4, DPP3; dipeptidyl-peptidase III [EC:3.4.14.4]
B Family M50: S2P protease family
C K07765 MBTPS2; S2P endopeptidase [EC:3.4.24.85]
C K06402 spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]
C K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M55: DppA aminopeptidase family
C K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
B Family M67
C K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
C K09613 COPS5, CSN5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
C K11867 STAMBPL1; AMSH-like protease [EC:3.1.2.15]
C K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3
C K11865 MYSM1; protein MYSM1
C K11866 STAMBP, AMSH; STAM-binding protein [EC:3.1.2.15]
B Family M74
C K07261 mepA; penicillin-insensitive murein endopeptidase [EC:3.4.24.-]
#
ASerine Peptidases
B Family S1: chymotrypsin family
C K01310 CTRB; chymotrypsin [EC:3.4.21.1]
C K09614 CORIN; corin [EC:3.4.21.-]
C K08661 MCPT1; mast cell peptidase 1 [EC:3.4.21.-]
C K08662 MCPT2; mast cell peptidase 2 [EC:3.4.21.-]
C K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
C K09615 TPSG1; tryptase gamma 1 [EC:3.4.21.-]
C K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
C K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
C K01319 CTSG; cathepsin G [EC:3.4.21.20]
C K01350 PRTN3; myeloblastin [EC:3.4.21.76]
C K01352 GZMA; granzyme A [EC:3.4.21.78]
C K01353 GZMB; granzyme B [EC:3.4.21.79]
C K09616 GZMH, CTSGL2; granzyme H (cathepsin G-like 2) [EC:3.4.21.-]
C K08663 GZMK; granzyme K [EC:3.4.21.-]
C K08649 GZMM; granzyme M [EC:3.4.21.-]
C K01329 CMA1; chymase [EC:3.4.21.39]
C K01326 CELA1; pancreatic elastase I [EC:3.4.21.36]
C K01346 CELA2; pancreatic elastase II [EC:3.4.21.71]
C K01345 CELA3; pancreatic endopeptidase E [EC:3.4.21.70]
C K01311 CTRC; chymotrypsin C [EC:3.4.21.2]
C K01325 KLK1_2; tissue kallikrein [EC:3.4.21.35]
C K01324 KLKB1; plasma kallikrein [EC:3.4.21.34]
C K01351 KLK3; semenogelase [EC:3.4.21.77]
C K08666 KLK4, PRSS17; kallikrein 4 (prostase, enamel matrix, prostate) [EC:3.4.21.-]
C K09617 KLK5; kallikrein 5 [EC:3.4.21.-]
C K08667 KLK6, PRSS9; kallikrein 6 (neurosin, zyme) [EC:3.4.21.-]
C K08668 KLK7, PRSS6; kallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]
C K08650 KLK8, PRSS19; kallikrein 8 (neuropsin/ovasin) [EC:3.4.21.118]
C K09618 KLK9; kallikrein 9 [EC:3.4.21.-]
C K09619 KLK10, PRSSL1; kallikrein 10 [EC:3.4.21.-]
C K09620 KLK11, PRSS20; kallikrein 11 [EC:3.4.21.-]
C K09621 KLK12; kallikrein 12 [EC:3.4.21.-]
C K09462 E3.4.21.119; glandular kallikrein 13 [EC:3.4.21.119]
C K09463 KLK13; kallikrein 13 [EC:3.4.21.-]
C K09622 KLK14; kallikrein 14 [EC:3.4.21.-]
C K09623 KLK15; kallikrein 15 [EC:3.4.21.-]
C K01339 KLK16; g-renin [EC:3.4.21.54]
C K01312 PRSS; trypsin [EC:3.4.21.4]
C K01316 PRSS7; protease, serine, 7 (enterokinase) [EC:3.4.21.9]
C K08664 PRSS8; protease, serine, 8 (prostasin) [EC:3.4.21.-]
C K09624 PRSS12; protease, serine, 12 (neurotrypsin, motopsin) [EC:3.4.21.-]
C K09625 PRSS21; protease, serine, 21 (testisin) [EC:3.4.21.-]
C K09626 PRSS22; protease, serine, 22 [EC:3.4.21.-]
C K09627 PRSS23; protease, serine, 23 [EC:3.4.21.-]
C K09628 PRSS27; protease, serine 27 [EC:3.4.21.-]
C K09629 PRSS33; protease, serine, 33
C K09630 PRSS36; protease, serine, 36 [EC:3.4.21.-]
C K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-]
C K03993 MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104]
C K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41]
C K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42]
C K01332 C2; complement component 2 [EC:3.4.21.43]
C K01335 CFB; component factor B [EC:3.4.21.47]
C K01334 CFD; component factor D [EC:3.4.21.46]
C K01333 CFI; complement factor I [EC:3.4.21.45]
C K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
C K01320 F7; coagulation factor VII [EC:3.4.21.21]
C K01321 F9; coagulation factor IX (Christmas factor) [EC:3.4.21.22]
C K01314 F10; coagulation factor X [EC:3.4.21.6]
C K01323 F11; coagulation factor XI [EC:3.4.21.27]
C K01328 F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38]
C K01344 PROC; protein C (activated) [EC:3.4.21.69]
C K01317 ACR; acrosin [EC:3.4.21.10]
C K08665 HPN; hepsin (transmembrane protease, serine 1) [EC:3.4.21.-]
C K09631 HGFAC; hepatocyte growth factor activator [EC:3.4.21.-]
C K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
C K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
C K01315 PLG; plasminogen [EC:3.4.21.7]
C K09632 CTRL; chymotrypsin-like protease [EC:3.4.21.-]
C K04775 ydgD; protease YdgD [EC:3.4.21.-]
C K01318 E3.4.21.19, sspA; glutamyl endopeptidase [EC:3.4.21.19]
C K04771 degP, htrA; serine protease Do [EC:3.4.21.107]
C K04772 degQ, hhoA; serine protease DegQ [EC:3.4.21.-]
C K04691 hhoB, degS; serine protease DegS [EC:3.4.21.-]
C K01337 E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
C K08784 HTRA1, PRSS11; HtrA serine peptidase 1 [EC:3.4.21.-]
C K08669 HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
C K08785 HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-]
C K08786 HTRA4; HtrA serine peptidase 4 [EC:3.4.21.-]
C K08670 ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
C K09633 TMPRSS2; transmembrane protease, serine 2
C K09634 TMPRSS3; transmembrane protease, serine 3 [EC:3.4.21.-]
C K09635 TMPRSS4; transmembrane protease, serine 4
C K09636 TMPRSS5; transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-]
C K09637 TMPRSS6; transmembrane protease, serine 6 [EC:3.4.21.-]
C K09638 TMPRSS7; transmembrane protease, serine 7 [EC:3.4.21.-]
C K09639 TMPRSS8; transmembrane protease, serine 8 [EC:3.4.21.-]
C K09640 TMPRSS9; transmembrane protease, serine 9 [EC:3.4.21.-]
C K09750 TMPRSS11A; transmembrane protease, serine 11A [EC:3.4.21.-]
C K09751 TMPRSS11B; transmembrane protease, serine 11B [EC:3.4.21.-]
C K14359 TMPRSS11C; transmembrane protease, serine 11C [EC:3.4.21.-]
C K09641 TMPRSS11D; transmembrane protease, serine 11D [EC:3.4.21.-]
C K09642 TMPRSS11E; transmembrane protease, serine 11E [EC:3.4.21.-]
C K09752 TMPRSS11F; transmembrane protease, serine 11F [EC:3.4.21.-]
C K09643 TMPRSS13, TMPRSS11; transmembrane protease, serine 13
C K09644 LPA; apolipoprotein(a) [EC:3.4.21.-]
C K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
C K16142 HP; haptoglobin
B Family S6
C K01347 iga; IgA-specific serine endopeptidase [EC:3.4.21.72]
B Family S8: subtilisin family
C K01342 aprE; subtilisin [EC:3.4.21.62]
C K13274 wprA; cell wall-associated protease [EC:3.4.21.-]
C K08651 E3.4.21.66; thermitase [EC:3.4.21.66]
C K13276 bpr; bacillopeptidase F [EC:3.4.21.-]
C K01361 E3.4.21.96; lactocepin [EC:3.4.21.96]
C K08652 C5AP, scpA, scpB; C5a peptidase [EC:3.4.21.110]
C K01336 E3.4.21.48; cerevisin [EC:3.4.21.48]
C K13275 isp; major intracellular serine protease [EC:3.4.21.-]
C K14644 OSW3, RRT12; subtilase-type proteinase RRT12 [EC:3.4.21.-]
C K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C K14645 K14645; serine protease [EC:3.4.21.-]
C K01341 E3.4.21.61; kexin [EC:3.4.21.61]
C K01349 FURIN, PCSK3; furin [EC:3.4.21.75]
C K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C K08671 PCSK4; proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-]
C K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C K08672 PCSK6; proprotein convertase subtilisin/kexin type 6 [EC:3.4.21.-]
C K08673 PCSK7; proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-]
C K13050 PCSK9; proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]
C K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
C K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-]
C K13277 epr; minor extracellular protease Epr [EC:3.4.21.-]
C K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C K01322 E3.4.21.26, PREP; prolyl oligopeptidase [EC:3.4.21.26]
C K08787 STE13; dipeptidyl aminopeptidase Ste13 [EC:3.4.14.-]
C K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C K08655 DPP8; dipeptidyl-peptidase 8 [EC:3.4.14.5]
C K08656 DPP9; dipeptidyl-peptidase 9 [EC:3.4.14.5]
C K01303 APEH; acylaminoacyl-peptidase [EC:3.4.19.1]
C K08674 FAP; fibroblast activation protein, alpha [EC:3.4.21.-]
C K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
C K13702 ABHD10; abhydrolase domain-containing protein 10
C K13704 ABHD12; abhydrolase domain-containing protein 12 [EC:3.1.1.23]
C K13705 ABHD12B; abhydrolase domain-containing protein 12B
C K13616 AADAC; arylacetamide deacetylase [EC:3.1.1.3]
C K14349 NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
B Family S10
C K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
C K01288 KEX1; carboxypeptidase D [EC:3.4.16.6]
C K09645 CPVL; vitellogenic carboxypeptidase-like protein [EC:3.4.16.-]
C K09646 SCPEP1; serine carboxypeptidase 1 [EC:3.4.16.-]
C K09757 SCPL8, SNG1; serine carboxypeptidase-like 8 [EC:3.4.16.- 2.3.1.92]
C K09756 SCPL19, SNG2; serine carboxypeptidase-like 19 [EC:3.4.16.- 2.3.1.91]
C K16296 SCPL-I; serine carboxypeptidase-like clade I [EC:3.4.16.-]
C K16297 SCPL-II; serine carboxypeptidase-like clade II [EC:3.4.16.-]
C K16298 SCPL-IV; serine carboxypeptidase-like clade IV [EC:3.4.16.-]
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C K07258 dacC, dacA, dacD; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C K07262 pbpG; D-alanyl-D-alanine endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S13: D-Ala-D-Ala peptidase C family
C K07259 dacB; D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C K01358 clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
C K01281 E3.4.14.11, pepXP; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
B Family S16: lon protease family
C K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C K08675 PRSS15, PIM1; Lon-like ATP-dependent protease [EC:3.4.21.-]
C K04076 lonB; Lon-like ATP-dependent protease [EC:3.4.21.-]
C K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-]
B Family S24: LexA family
C K01356 lexA; repressor LexA [EC:3.4.21.88]
C K03503 DPO5D, umuD; DNA polymerase V [EC:3.4.21.-]
B Family S26: signal peptidase I family
C K03100 lepB; signal peptidase I [EC:3.4.21.89]
C K13280 SEC11, sipW; signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-]
C K09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
C K09648 IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
B Family S28
C K01285 PRCP; lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]
C K01276 DPP7; dipeptidyl-peptidase II [EC:3.4.14.2]
C K09649 PRSS16; protease, serine, 16 (thymus) [EC:3.4.-.-]
B Family S33
C K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C K13698 ABHD4; abhydrolase domain-containing protein 4
C K13699 ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
C K13700 ABHD6; abhydrolase domain-containing protein 6 [EC:3.1.1.23]
C K13701 ABHD8; abhydrolase domain-containing protein 8
C K13703 ABHD11; abhydrolase domain-containing protein 11
C K13706 ABHD14; abhydrolase domain-containing protein 14
C K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
C K13617 PPME1; protein phosphatase methylesterase 1 [EC:3.1.1.89]
B Family S41: C-terminal processing peptidase family
C K03797 E3.4.21.102, prc, ctpA; carboxyl-terminal processing protease [EC:3.4.21.102]
C K08676 tri; tricorn protease [EC:3.4.21.-]
B Family S45: cephalosporin acylase precursor
C K12748 gca; glutaryl-7-aminocephalosporanic-acid acylase [EC:3.5.1.93]
B Family S49: protease IV family
C K04773 sppA; protease IV [EC:3.4.21.-]
C K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S51
C K05995 pepE; dipeptidase E [EC:3.4.13.21]
C K13282 cphB; cyanophycinase [EC:3.4.15.6]
B Family S53
C K05998 E3.4.21.100; pseudomonalisin [EC:3.4.21.100]
C K05999 E3.4.21.101; xanthomonalisin [EC:3.4.21.101]
C K01279 TPP1, CLN2; tripeptidyl-peptidase I [EC:3.4.14.9]
C K08677 K08677; kumamolisin
B Family S54: Rhomboid family
C K02857 RHBDL1_2_3; rhomboid-related protein 1/2/3 [EC:3.4.21.105]
C K09650 PARL, PSARL, PCP1; rhomboid-like protein [EC:3.4.21.105]
C K09651 RHBDD1; rhomboid domain-containing protein 1 [EC:3.4.21.-]
C K09652 RHBDD2, RHBDL7; rhomboid domain-containing protein 2
B Family S55: SpoIVB peptidase family
C K06399 spoIVB; stage IV sporulation protein B [EC:3.4.21.116]
B Family S58: DmpA aminopeptidase family
C K01266 E3.4.11.19, dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family S66
C K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
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AThreonine Peptidases
B Family T1: proteasome family
C K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
C K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
C K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
C K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
C K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
C K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
C K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
C K03432 psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
C K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
C K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
C K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
C K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
C K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
C K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
C K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
C K02740 PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]
C K02741 PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]
C K02733 PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]
C K03433 psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
C K01419 hslV, clpQ; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C K13051 iaaA, ASRGL1; beta-aspartyl-peptidase (threonine type) [EC:3.4.19.5]
C K08657 TASP1; taspase, threonine aspartase, 1 [EC:3.4.25.-]
B Family T3: gamma-glutamyltransferase family
C K00681 ggt; gamma-glutamyltranspeptidase [EC:2.3.2.2]
#
APeptidases of Unknown Catalytic Type
B Family U4: SpoIIGA peptidase family
C K06383 spoIIGA; stage II sporulation protein GA (sporulation sigma-E factor processing peptidase) [EC:3.4.23.-]
B Family U32
C K08303 K08303; putative protease [EC:3.4.-.-]
B Family U48: prenyl protease 2 family
C K08658 RCE1, FACE2; prenyl protein peptidase [EC:3.4.22.-]
B Family U62
C K03592 pmbA; PmbA protein
C K03568 tldD; TldD protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 17, 2013
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Classification taken and modified from MEROPS