+E Ubiquitin system
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Ubiquitin System
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AUbiquitins and Ubiquitin-like proteins
B Ubiquitins
C K04551 UBB; ubiquitin B
C K08770 UBC; ubiquitin C
C K12157 UBD, FAT10; ubiquitin D
B Ubiquitin-like proteins (UBLs)
C K12158 NEDD8; ubiquitin-like protein Nedd8
C K02983 RP-S30e, RPS30; small subunit ribosomal protein S30e
C K12159 ISG15; ubiquitin cross-reactive protein
C K12160 SUMO, SMT3; small ubiquitin-related modifier
C K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein (autophagy-related protein 8)
C K08336 ATG12; autophagy-related protein 12
C K12161 URM1; ubiquitin related modifier 1
C K12162 UFM1; ubiquitin-fold modifier 1
C K12163 ANUBL1; AN1-type zinc finger and ubiquitin domain-containing protein 1
C K13570 pup; prokaryotic ubiquitin-like protein Pup
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C K03178 UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.3.2.19]
B UBL-activating enzymes
C K10684 UBLE1A, SAE1; ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19]
C K10685 UBLE1B, SAE2, UBA2; ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]
C K10686 UBE1C, UBA3; ubiquitin-activating enzyme E1 C [EC:6.3.2.19]
C K04532 APPBP1; amyloid beta precursor protein binding protein 1
C K11996 MOCS3, UBA4, moeB; adenylyltransferase and sulfurtransferase
C K12164 UBA5, UBE1DC1; ubiquitin-like modifier-activating enzyme 5
C K10698 UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.3.2.19]
C K10699 UBE1L2, UBA6; ubiquitin-activating enzyme E1-like protein 2 [EC:6.3.2.19]
C K08337 ATG7; autophagy-related protein 7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C K10573 UBE2A, UBC2, RAD6A; ubiquitin-conjugating enzyme E2 A [EC:6.3.2.19]
C K10574 UBE2B, RAD6B; ubiquitin-conjugating enzyme E2 B [EC:6.3.2.19]
C K06688 UBE2C, UBC11; ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]
C K06689 UBE2D_E, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]
C K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:6.3.2.19]
C K10575 UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19]
C K04555 UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19]
C K10576 UBE2H, UBC8; ubiquitin-conjugating enzyme E2 H [EC:6.3.2.19]
C K10578 UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:6.3.2.19]
C K04554 UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19]
C K04552 UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19]
C K04553 UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6 [EC:6.3.2.19]
C K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:6.3.2.19]
C K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:6.3.2.19]
C K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19]
C K02207 UBE2R, UBC3, CDC34; ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19]
C K10583 UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S [EC:6.3.2.19]
C K13960 UBE2T, HSPC150; ubiquitin-conjugating enzyme E2 T [EC:6.3.2.19]
C K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:6.3.2.19]
C K10688 UBE2W, UBC16; ubiquitin-conjugating enzyme E2 W [EC:6.3.2.19]
C K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:6.3.2.19]
C K04649 HIP2, UBC1; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19]
C K10586 BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:6.3.2.19]
C K10689 PEX4; peroxin-4 [EC:6.3.2.19]
C K10690 UBE2X; ubiquitin-conjugating enzyme E2, other [EC:6.3.2.19]
B UBL-conjugating enzymes
C K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
C K04553 UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6 [EC:6.3.2.19]
C K10579 UBE2M, UBC12; ubiquitin-conjugating enzyme E2 M [EC:6.3.2.19]
C K08343 ATG3; autophagy-related protein 3
C K08338 ATG10; autophagy-related protein 10
C K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C K10587 UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:6.3.2.19]
C K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:6.3.2.19]
C K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:6.3.2.19]
C K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19]
C K05630 WWP2, AIP2; atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:6.3.2.19]
C K05632 AIP4, ITCH; atrophin-1 interacting protein 4 [EC:6.3.2.19]
C K05633 AIP5, WWP1; atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19]
C K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19]
C K10591 NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
C K13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:6.3.2.19]
C K10592 HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1 [EC:6.3.2.19]
C K10593 EDD1, UBR5; E3 ubiquitin-protein ligase EDD1 [EC:6.3.2.19]
C K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:6.3.2.19]
C K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19]
C K10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19]
C K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19]
C K12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:6.3.2.19]
C K12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:6.3.2.19]
C K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:6.3.2.19]
C K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:6.3.2.19]
C K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:6.3.2.19]
C K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:6.3.2.19]
C K03874 HECT; other hect domain ubiquitin protein ligase E3 [EC:6.3.2.19]
B U-box type E3
C K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:6.3.2.19]
C K10597 UBE4B, UFD2; ubiquitin conjugation factor E4 B [EC:6.3.2.19]
C K09561 STUB1, CHIP; STIP1 homology and U-box containing protein 1 [EC:6.3.2.19]
C K10598 PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C K10599 PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:6.3.2.19]
C K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:6.3.2.19]
C K10600 UBOX5, UIP5; U-box domain-containing protein 5
B single Ring-finger type E3
C BRE1 protein
D K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:6.3.2.19]
C CBL protein
D K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
C SINA (Seven in absentia) proteins
D K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19]
D K08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:6.3.2.19]
C Ligand of Numb proteins
D K10692 LNX1_2; ligand of Numb protein X 1/2
D K15682 PDZRN3_4, LNX3_4; ligand of Numb protein X 3/4
C March proteins
D K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:6.3.2.19]
D K10657 MARCH2; E3 ubiquitin-protein ligase MARCH2 [EC:6.3.2.19]
D K10658 MARCH3; E3 ubiquitin-protein ligase MARCH3 [EC:6.3.2.19]
D K10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:6.3.2.19]
D K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19]
D K10661 MARCH6, DOA10; E3 ubiquitin-protein ligase MARCH6 [EC:6.3.2.19]
D K10662 MARCH7, AXOT; E3 ubiquitin-protein ligase MARCH7 [EC:6.3.2.19]
D K10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:6.3.2.19]
C MDM2/MDM4 proteins
D K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
D K10127 MDM4, MDMX; protein Mdm4
C NFX1 proteins
D K12236 NFX1; transcriptional repressor NF-X1 [EC:6.3.2.-]
D K15683 NFXL1, OZFP; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D K11964 PELI; pellino
C Peripheral membrane proteins
D K13346 PEX10; peroxin-10
D K13345 PEX12, PAF3; peroxin-12
D K06664 PEX2, PXMP3; peroxin-2
C RBR proteins
D K04556 PARK2; parkin [EC:6.3.2.19]
D K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1
D K11968 ARIH1; ariadne-1
D K11969 ARIH2; ariadne-2
D K11970 CUL9, PARC; p53-associated parkin-like cytoplasmic protein
D K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1
D K11971 RNF14, ARA54; E3 ubiquitin-protein ligase RNF14 [EC:6.3.2.19]
D K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:6.3.2.19]
D K11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:6.3.2.19]
D K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:6.3.2.19]
D K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:6.3.2.19]
D K11976 RNF216; TRIAD3; E3 ubiquitin-protein ligase RNF216 [EC:6.3.2.19]
D K11977 RNF217, IBRDC1; E3 ubiquitin-protein ligase RNF217 [EC:6.3.2.19]
C TRAF proteins
D K03173 TRAF2; TNF receptor-associated factor 2
D K09849 TRAF5; TNF receptor-associated factor 5
D K03175 TRAF6; TNF receptor-associated factor 6
D K10646 TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7 [EC:6.3.2.19]
C TRIM/RBCC proteins
D K10647 TRIM1, MID2; midline 2
D K11997 TRIM2_3; tripartite motif-containing protein 2/3
D K11998 TRIM4; tripartite motif-containing protein 4
D K10648 TRIM5; tripartite motif-containing protein 5 [EC:6.3.2.19]
D K11999 TRIM6_22_34; tripartite motif-containing protein 6/22/34
D K12000 TRIM7; tripartite motif-containing protein 7
D K12001 TRIM8; tripartite motif-containing protein 8
D K10649 TRIM9_67; tripartite motif-containing protein 9/67
D K12002 TRIM10; tripartite motif-containing protein 10
D K10650 TRIM11; tripartite motif-containing protein 11 [EC:6.3.2.19]
D K12003 TRIM13; tripartite motif-containing protein 13
D K12004 TRIM14; tripartite motif-containing protein 14
D K12005 TRIM15; tripartite motif-containing protein 15
D K12006 TRIM16; tripartite motif-containing protein 16
D K12007 TRIM17; tripartite motif-containing protein 17
D K08285 TRIM18, MID1; midline 1 [EC:6.3.2.19]
D K10054 PML, TRIM19; probable transcription factor PML
D K10651 TRIM21, SSA1; tripartite motif-containing protein 21
D K07963 TRIM23, ARFD1; tripartite motif-containing protein 23
D K08881 TRIM24, TIF1; tripartite motif-containing protein 24
D K10652 TRIM25, EFP; tripartite motif-containing protein 25
D K12008 TRIM26; tripartite motif-containing protein 26
D K12009 TRIM27, RFP; tripartite motif-containing protein 27
D K08882 TRIM28; tripartite motif-containing protein 28
D K12010 TRIM29, ATDC; tripartite motif-containing protein 29
D K12011 TRIM31; tripartite motif-containing protein 31
D K10607 TRIM32, HT2A; tripartite motif-containing protein 32 [EC:6.3.2.19]
D K08883 TRIM33; tripartite motif-containing protein 33 [EC:6.3.2.19]
D K12012 TRIM35; tripartite motif-containing protein 35
D K12013 TRIM36; tripartite motif-containing protein 36
D K10608 TRIM37, MUL; tripartite motif-containing protein 37
D K12014 TRIM38; tripartite motif-containing protein 38
D K12015 TRIM39; tripartite motif-containing protein 39
D K12016 TRIM40; tripartite motif-containing protein 40
D K12017 TRIM41; tripartite motif-containing protein 41
D K12018 TRIM42; tripartite motif-containing protein 42
D K12019 TRIM43S; tripartite motif-containing protein 43/48/49/64/77
D K12020 TRIM44; tripartite motif-containing protein 44
D K12021 TRIM45; tripartite motif-containing protein 45
D K12022 TRIM46; tripartite motif-containing protein 46
D K12023 TRIM47; tripartite motif-containing protein 47
D K12024 TRIM50_73_74; tripartite motif-containing protein 50/73/74
D K12025 TRIM52; tripartite motif-containing protein 52
D K10653 TRIM54, MURF3; tripartite motif-containing protein 54
D K10654 TRIM55, MURF2; tripartite motif-containing protein 55
D K12026 TRIM56; tripartite motif-containing protein 56
D K12027 TRIM58; tripartite motif-containing protein 58
D K12028 TRIM59; tripartite motif-containing protein 59
D K12029 TRIM60_61; tripartite motif-containing protein 60/61
D K12030 TRIM62; tripartite motif-containing protein 62
D K10655 TRIM63, MURF1; tripartite motif-containing protein 63 [EC:6.3.2.19]
D K12031 TRIM65; tripartite motif-containing protein 65
D K12032 TRIM66; tripartite motif-containing protein 66
D K12033 TRIM68; tripartite motif-containing protein 68
D K12034 TRIM69; tripartite motif-containing protein 69
D K12035 TRIM71; tripartite motif-containing protein 71
D K12036 TRIM72; tripartite motif-containing protein 72
D K12037 TRIM75; tripartite motif-containing protein 75
C UBR box proteins
D K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:6.3.2.19]
D K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:6.3.2.19]
D K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:6.3.2.19]
D K10691 UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19]
D K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:6.3.2.19]
C Other single Ring-finger type E3
D K10636 AMFR, GP78; autocrine motility factor receptor [EC:6.3.2.19]
D K10603 AIRE; autoimmune regulator
D K15684 BFAR; bifunctional apoptosis regulator
D K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
D K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D K10632 BRAP; BRCA1-associated protein [EC:6.3.2.19]
D K10605 BRCA1; breast cancer type 1 susceptibility protein
D K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:6.3.2.19]
D K10639 CCNB1IP1, HEI10; E3 ubiquitin-protein ligase CCNP1IP1 [EC:6.3.2.19]
D K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:6.3.2.19]
D K10643 CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:6.3.2.19]
D K06058 DTX; deltex
D K10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:6.3.2.19]
D K10606 FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19]
D K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19]
D K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D K15686 MEX3, RKHD; RNA-binding protein MEX3
D K10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:6.3.2.19]
D K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19]
D K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:6.3.2.19]
D K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:6.3.2.19]
D K10693 MYCBP2, PAM; E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19]
D K10637 MYLIP, MIR; E3 ubiquitin-protein ligase MYLIP [EC:6.3.2.19]
D K01931 NEUR; protein neuralized [EC:6.3.2.19]
D K15689 NEURL3, LINCR; E3 ubiquitin-protein ligase NEURL3 [EC:6.3.2.19]
D K10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:6.3.2.19]
D K10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:6.3.2.19]
D K10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:6.3.2.19]
D K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:6.3.2.19]
D K10628 RAG1; V(D)J recombination-activating protein 1 [EC:6.3.2.19]
D K10144 RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:6.3.2.19]
D K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D K10143 RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]
D K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:6.3.2.19]
D K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:6.3.2.19]
D K10666 RNF5; E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19]
D K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:6.3.2.19]
D K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D K16271 RLIM, RNF12; E3 ubiquitin-protein ligase RLIM [EC:6.3.2.19]
D K15692 RNF13, RZF; E3 ubiquitin-protein ligase RNF13 [EC:6.3.2.19]
D K10640 RNF25, AO7; E3 ubiquitin-protein ligase RNF25 [EC:6.3.2.19]
D K15693 RNF26; RING finger protein 26
D K11981 RNF41, NRDP1; E3 ubiquitin-protein ligase NRDP1 [EC:6.3.2.19]
D K15694 RNF43; RING finger protein 43
D K15695 RNF103, KF1; E3 ubiquitin-protein ligase RNF103 [EC:6.3.2.19]
D K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:6.3.2.19]
D K15696 RNF113B; RING finger protein 113B
D K15697 RNF114; RING finger protein 114
D K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19]
D K15698 RNF121; RING finger protein 121
D K15699 RNF122; RING finger protein 122
D K12169 KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19]
D K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:6.3.2.19]
D K10629 RNF128, GRAIL; E3 ubiquitin-protein ligase RNF128 [EC:6.3.2.19]
D K15701 RNF130, GOLIATH; E3 ubiquitin-protein ligase RNF130 [EC:6.3.2.19]
D K15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:6.3.2.19]
D K16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:6.3.2.19]
D K10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:6.3.2.19]
D K15703 RNF139, TRC8; E3 ubiquitin-protein ligase RNF139 [EC:6.3.2.19]
D K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:6.3.2.19]
D K15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:6.3.2.19]
D K15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:6.3.2.19]
D K15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:6.3.2.19]
D K15707 RNF170; RING finger protein 170
D K15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:6.3.2.19]
D K11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:6.3.2.19]
D K15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:6.3.2.19]
D K11984 SART1, HAF, SNU66; U4/U6.U5 tri-snRNP-associated protein 1
D K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 6.3.2.19]
D K12171 SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF [EC:6.3.2.19]
D K15711 SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 6.3.2.19]
D K10601 SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19]
D K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:6.3.2.19]
D K11985 TRAIP, TRIP; TRAF-interacting protein
D K15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:6.3.2.19]
D K10638 UHRF1, NP95; E3 ubiquitin-protein ligase UHRF1 [EC:6.3.2.19]
D K15713 UHRF2, NIRF; E3 ubiquitin-protein ligase UHRF2 [EC:6.3.2.19]
D K15714 ZNF645; E3 ubiquitin-protein ligase ZNF645 [EC:6.3.2.19]
D K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:6.3.2.19]
D K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:6.3.2.19]
D K15715 ZNRF4; Zinc/RING finger protein 4
D K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:6.3.2.19]
D K16274 AIP2; E3 ubiquitin-protein ligase AIP2 [EC:6.3.2.19]
D K16275 BAH, NLA; E3 ubiquitin-protein ligase BAH [EC:6.3.2.19]
D K16276 K16276, BTS; zinc finger protein-like protein
D K16277 DRIP; E3 ubiquitin-protein ligase DRIP [EC:6.3.2.19]
D K16278 K16278, HOS1; E3 ubiquitin-protein ligase HOS1 [EC:6.3.2.19]
D K16279 KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 6.3.2.19]
D K16280 RGLG; E3 ubiquitin-protein ligase RGLG [EC:6.3.2.19]
D K16281 RHA1; RING-H2 zinc finger protein RHA1
D K16282 RHA2; E3 ubiquitin-protein ligase RHA2 [EC:6.3.2.19]
D K16283 SDIR1; E3 ubiquitin-protein ligase SDIR1 [EC:6.3.2.19]
D K16284 SIS3; E3 ubiquitin-protein ligase SIS3 [EC:6.3.2.19]
D K16285 XERICO; RING/U-box domain-containing protein
D K16286 EL5; E3 ubiquitin-protein ligase EL5 [EC:6.3.2.19]
B UBL E3 ligases
C K12172 RANBP2, NUP358; E3 SUMO-protein ligase RanBP2
C K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:6.3.2.19]
C K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-]
C K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
C K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:6.3.2.-]
C K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
C K11452 CBX4, PC2; chromobox protein 4
C K03868 RBX1, ROC1; RING-box protein 1
B multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E K03868 RBX1, ROC1; RING-box protein 1
D Cullin
E K03347 CUL1, CDC53; cullin 1
D adaptor protein
E K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
D target recognizing subunit (F-box)
E K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
E K10261 FBXW2, MD6; F-box and WD-40 domain protein 2
E K10262 FBXW4, SHFM3; F-box and WD-40 domain protein 4
E K10263 FBXW5; F-box and WD-40 domain protein 5
E K10260 FBXW7, SEL10; F-box and WD-40 domain protein 7
E K10264 FBXW8; F-box and WD-40 domain protein 8
E K10265 FBXW9; F-box and WD-40 domain protein 9
E K10266 FBXW10; F-box and WD-40 domain protein 10
E K10267 FBXW12S; F-box and WD-40 domain protein 12/13/14/15/16/17/19
E K10259 MET30; F-box and WD-40 domain protein MET30
E K03361 CDC4; F-box and WD-40 domain protein CDC4
E K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E K10269 FBXL3; F-box and leucine-rich repeat protein 3
E K10270 FBXL4; F-box and leucine-rich repeat protein 4
E K10271 FBXL5; F-box and leucine-rich repeat protein 5
E K10272 FBXL6; F-box and leucine-rich repeat protein 6
E K10273 FBXL7; F-box and leucine-rich repeat protein 7
E K10274 FBXL8; F-box and leucine-rich repeat protein 8
E K10275 FBXL9, LRRC29; F-box and leucine-rich repeat protein 9
E K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E K10278 FBXL12; F-box and leucine-rich repeat protein 12
E K10279 FBXL13; F-box and leucine-rich repeat protein 13
E K10280 FBXL14; F-box and leucine-rich repeat protein 14
E K10281 FBXL15; F-box and leucine-rich repeat protein 15
E K10282 FBXL16; F-box and leucine-rich repeat protein 16
E K10283 FBXL17; F-box and leucine-rich repeat protein 17
E K10284 FBXL18; F-box and leucine-rich repeat protein 18
E K10285 FBXL19; F-box and leucine-rich repeat protein 19
E K10287 FBXL21; F-box and leucine-rich repeat protein 21
E K10288 FBXL22; F-box and leucine-rich repeat protein 22
E K13463 COI-1; coronatine-insensitive protein 1
E K14515 EBF1_2; EIN3-binding F-box protein
E K14485 TIR1; transport inhibitor response 1
E K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E K15068 DIA2, POF3; protein DIA2
E K15069 POF3; F-box/TPR repeat protein Pof3
E K10289 CCNF, FBXO1; F-box protein 1 (cyclin F)
E K10099 FBXO2, NFB42; F-box protein 2
E K10290 FBXO3; F-box protein 3
E K10291 FBXO4; F-box protein 4
E K10292 FBXO5, EMI1; F-box protein 5
E K10100 FBXO6; F-box protein 6
E K10293 FBXO7; F-box protein 7
E K10294 FBXO8; F-box protein 8
E K10295 FBXO9; F-box protein 9
E K10296 FBXO10; F-box protein 10
E K10297 FBXO11; F-box protein 11
E K10298 FBXO15; F-box protein 15
E K10299 FBXO16; F-box protein 16
E K10101 FBXO17, FBXO26; F-box protein 17
E K10300 FBXO18; F-box protein, helicase, 18 [EC:3.6.4.12]
E K06084 LMO7, FBXO20; F-box protein 20
E K10301 FBXO21; F-box protein 21
E K10302 FBXO22; F-box protein 22
E K10303 FBXO23, TSPAN17; F-box protein 23
E K10304 FBXO24; F-box protein 24
E K10305 FBXO25_32; F-box protein 25/32
E K10102 FBXO27; F-box protein 27
E K10306 FBXO28; F-box protein 28
E K10307 FBXO30; F-box protein 30
E K10308 FBXO31; F-box protein 31
E K10310 FBXO33; F-box protein 33
E K10311 FBXO34; F-box protein 34
E K10312 FBXO36; F-box protein 36
E K10313 FBXO38, MOKA; F-box protein 38
E K10314 FBXO39; F-box protein 39
E K10315 FBXO40; F-box protein 40
E K10316 FBXO41; F-box protein 41
E K10317 FBXO42; F-box protein 42
E K10318 FBXO43, EMI2; F-box protein 43
E K10103 FBXO44; F-box protein 44
E K10319 FBXO45; F-box protein 45
E K10320 FBXO46; F-box protein 46
E K10321 FBXO47; F-box protein 47
E K12116 FKF1; flavin-binding kelch repeat F-box protein 1
E K14495 GID2, SLY1; F-box protein GID2
E K12117 LKP2; LOV kelch protein 2
E K12115 ZTL; clock-associated PAS protein ZTL
E K15070 MDM30; mitochondrial distribution and morphology protein 30
E K15071 RCY1, POF6; recyclin-1
E K15072 SAF1; SCF-associated factor 1
E K15073 UFO1; ubiquitin ligase complex F-box protein UFO1
C ECV complex
D Ring finger protein
E K03868 RBX1, ROC1; RING-box protein 1
D Cullin
E K03870 CUL2; cullin 2
D adoptor protein
E K03872 TCEB1; transcription elongation factor B, polypeptide 1
E K03873 TCEB2; transcription elongation factor B, polypeptide 2
D target recognizing subunit (VHL box)
E K03871 VHL; von Hippel-Lindau disease tumor supressor
E K10348 LRR1, PPIL5; LRR-repeat protein 1
E K10349 FEM1B; Fem-1 homolog b
E K10350 ZYG11; Zyg-11 protein homolog
C Cul3 complex
D Ring finger protein
E K03868 RBX1, ROC1; RING-box protein 1
D Cullin
E K03869 CUL3; cullin 3
D target recognizing subunit (BTB)
E K10442 KLHL1_4_5; kelch-like protein 1/4/5
E K10443 KLHL2_3; kelch-like protein 2/3
E K10444 KLHL6; kelch-like protein 6
E K10445 KLHL7; kelch-like protein 7
E K10446 KLHL8; kelch-like protein 8
E K10447 KLHL9_13; kelch-like protein 9/13
E K10448 KLHL10; kelch-like protein 10
E K10449 KLHL11; kelch-like protein 11
E K10450 KLHL12, C3IP1; kelch-like protein 12
E K10451 KLHL14; kelch-like protein 14
E K10452 KLHL15; kelch-like protein 15
E K10453 KLHL16, GAN; kelch-like protein 16 (gigaxonin)
E K10454 KLHL17; kelch-like protein 17 (actinfilin)
E K10455 KLHL18; kelch-like protein 18
E K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
E K10457 KLHL20, KLEIP; kelch-like protein 20
E K10458 KLHL21; kelch-like protein 21
E K10459 KLHL22, KELCHL; kelch-like protein 22
E K10460 KLHL23; kelch-like protein 23
E K10461 KLHL24_35; kelch-like protein 24/35
E K10462 KLHL25_37, ENC1, ENC2; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E K10463 KLHL26; kelch-like protein 26
E K13956 IPP, KLHL27; actin-binding protein IPP
E K10464 KLHL28; kelch-like protein 28
E K10465 KLHL29, KBTBD9; kelch-like protein 29
E K10466 KLHL30; kelch-like protein 30
E K10467 KLHL31; kelch-like protein 31
E K10468 KLHL32; kelch-like protein 32
E K13957 KLHL33; kelch-like protein 33
E K10469 KLHL34; kelch-like protein 34
E K13958 KLHL36; kelch-like protein 36
E K13959 KLHL38; kelch-like protein 38
E K10470 KBTBD2; kelch repeat and BTB domain-containing protein 2
E K10471 KBTBD3; kelch repeat and BTB domain-containing protein 3
E K10472 KBTBD4; kelch repeat and BTB domain-containing protein 4
E K10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5/10
E K10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6/7
E K10475 KBTBD8; kelch repeat and BTB domain-containing protein 8
E K10476 KBTBD11; kelch repeat and BTB domain-containing protein 11
E K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E K10479 BTBD7; BTB/POZ domain-containing protein 7
E K10480 BTBD8; BTB/POZ domain-containing protein 8
E K10481 BTBD9; BTB/POZ domain-containing protein 9
E K10482 BTBD10; BTB/POZ domain-containing protein 10
E K10483 BTBD11; BTB/POZ domain-containing protein 11
E K10484 BTBD12, SLX4; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E K10485 BTBD13, GMCL1, GCL; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E K10486 BTBD14; BTB/POZ domain-containing protein 14
E K10487 BTBD16; BTB/POZ domain-containing protein 16
E K10488 ZBTB1; zinc finger and BTB domain-containing protein 1
E K10489 ZBTB2; zinc finger and BTB domain-containing protein 2
E K10490 ZBTB3; zinc finger and BTB domain-containing protein 3
E K10491 ZBTB4; zinc finger and BTB domain-containing protein 4
E K10492 ZBTB5; zinc finger and BTB domain-containing protein 5
E K10493 ZBTB6; zinc finger and BTB domain-containing protein 6
E K10494 ZBTB7; zinc finger and BTB domain-containing protein 7
E K10495 ZBTB8; zinc finger and BTB domain-containing protein 8
E K10496 ZBTB9; zinc finger and BTB domain-containing protein 9
E K10497 ZBTB10, RINZF; zinc finger and BTB domain-containing protein 10
E K10498 ZBTB11; zinc finger and BTB domain-containing protein 11
E K10499 ZBTB12; zinc finger and BTB domain-containing protein 12
E K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
E K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
E K10501 ZBTB20, HOF, DPZF; zinc finger and BTB domain-containing protein 20
E K10502 ZBTB22, BING1; zinc finger and BTB domain-containing protein 22
E K10503 ZBTB24, BIF1; zinc finger and BTB domain-containing protein 24
E K10504 ZBTB25; zinc finger and BTB domain-containing protein 25
E K10505 ZBTB26; zinc finger and BTB domain-containing protein 26
E K10506 ZBTB32, TZFP; zinc finger and BTB domain-containing protein 32
E K10507 ZBTB33, KAISO; zinc finger and BTB domain-containing protein 33
E K10508 ZBTB34; zinc finger and BTB domain-containing protein 34
E K10509 ZBTB37; zinc finger and BTB domain-containing protein 37
E K10510 ZBTB38; zinc finger and BTB domain-containing protein 38
E K10511 ZBTB39; zinc finger and BTB domain-containing protein 39
E K10512 ZBTB40; zinc finger and BTB domain-containing protein 40
E K10513 ZBTB41; zinc finger and BTB domain-containing protein 41
E K10514 ZBTB43; zinc finger and BTB domain-containing protein 43
E K10515 ZBTB44, BTBD15; zinc finger and BTB domain-containing protein 44
E K10516 ZBTB45; zinc finger and BTB domain-containing protein 45
E K10517 ZBTB46, BTBD4; zinc finger and BTB domain-containing protein 46
E K10518 ZBTB47; zinc finger and BTB domain-containing protein 47
E K10519 ZBTB48, HKR3; zinc finger and BTB domain-containing protein 48
E K10520 ABTB1, BPOZ; ankyrin repeat and BTB/POZ domain-containing protein 1
E K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E K07869 RHOBTB3; Rho-related BTB domain-containing protein 3
E K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E K10522 DIABLO, SMAC; diablo
E K10523 SPOP; speckle-type POZ protein
E K14508 NPR1; regulatory protein NPR1
E K03876 MEL26; BTB domain ubiquitin protein ligase cofactor
C Cul4 complex
D Ring finger protein
E K03868 RBX1, ROC1; RING-box protein 1
D Cullin
E K10609 CUL4; cullin 4
D adoptor protein
E K10610 DDB1; DNA damage-binding protein 1
D target recognizing subunit (DCAF)
E K10140 DDB2; DNA damage-binding protein 2
E K10570 ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
E K10571 DET1; de-etiolated-1
E K10143 RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]
E K11789 VPRBP, DCAF1; HIV-1 Vpr-binding protein
E K11790 DTL, CDT2, DCAF2; denticleless
E K11791 DCAF15; DDB1- and CUL4-associated factor 15
E K11792 DDA1; DET1- and DDB1-associated protein 1
E K11793 CRBN; cereblon
E K11794 IFRG15; IFRG15 protein
E K11795 IQWD1, NRIP, ARCAP; nuclear receptor interaction protein
E K11796 TRPC4AP; Trpc4-associated protein
E K11797 PHIP, WDR11; PH-interacting protein
E K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E K11799 WDR21A; WD repeat-containing protein 21A
E K11800 WDR22, BCRP2; WD repeat-containing protein 22
E K11801 WDR23; WD repeat-containing protein 23
E K11802 WDR32; WD repeat-containing protein 32
E K11803 WDR40A; WD repeat-containing protein 40A
E K11804 WDR42A; WD repeat-containing protein 42A
E K11805 WDR68, HAN11; WD repeat-containing protein 68
E K11806 WDSOF1; WD repeat and SOF domain-containing protein 1
E K11807 WDTC1; WD and tetratricopeptide repeats protein 1
C ECS complex
D Ring finger protein
E K10611 RBX2, ROC2, RNF7; RING-box protein 2
D Cullin
E K10612 CUL5; cullin 5
D adoptor protein
E K03872 TCEB1; transcription elongation factor B, polypeptide 1
E K03873 TCEB2; transcription elongation factor B, polypeptide 2
D target recognizing subunit (SOCS box)
E K04701 CISH; cytokine inducible SH2-containing protein
E K04694 SOCS1, JAB; suppressor of cytokine signaling 1
E K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
E K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
E K04697 SOCS4; suppressor of cytokine signaling 4
E K04698 SOCS5; suppressor of cytokine signaling 5
E K10322 SOCS6, CIS4; suppressor of cytokine signaling 6
E K04699 SOCS7, NAP4; suppressor of cytokine signaling 7
E K10323 ASB1; ankyrin repeat and SOCS box protein 1
E K10324 ASB2; ankyrin repeat and SOCS box protein 2
E K10325 ASB3; ankyrin repeat and SOCS box protein 3
E K10326 ASB4; ankyrin repeat and SOCS box protein 4
E K10327 ASB5; ankyrin repeat and SOCS box protein 5
E K10328 ASB6; ankyrin repeat and SOCS box protein 6
E K10329 ASB7; ankyrin repeat and SOCS box protein 7
E K10330 ASB8; ankyrin repeat and SOCS box protein 8
E K10331 ASB9; ankyrin repeat and SOCS box protein 9
E K10332 ASB10; ankyrin repeat and SOCS box protein 10
E K10333 ASB11; ankyrin repeat and SOCS box protein 11
E K10334 ASB12; ankyrin repeat and SOCS box protein 12
E K10335 ASB13; ankyrin repeat and SOCS box protein 13
E K10336 ASB14; ankyrin repeat and SOCS box protein 14
E K10337 ASB15; ankyrin repeat and SOCS box protein 15
E K10338 ASB16; ankyrin repeat and SOCS box protein 16
E K10339 ASB17; ankyrin repeat and SOCS box protein 17
E K10340 ASB18; ankyrin repeat and SOCS box protein 18
E K10341 WSB1; WD repeat and SOCS box-containing protein 1
E K10342 WSB2; WD repeat and SOCS box-containing protein 2
E K10343 SPSB1_4, SSB1, SSB4; SPRY domain-containing SOCS box protein 1/4
E K10344 SPSB2, SSB2; SPRY domain-containing SOCS box protein 2
E K10345 SPSB3, SSB3; SPRY domain-containing SOCS box protein 3
E K07928 RAB40; Ras-related protein Rab-40
E K10347 LRRC41, MUF1; leucine-rich repeat-containing protein 41
C Cul7 complex
D Ring finger protein
E K03868 RBX1, ROC1; RING-box protein 1
D Cullin
E K10613 CUL7; cullin 7
D adaptor protein
E K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
D target recognizing subunit
E K10264 FBXW8; F-box and WD-40 domain protein 8
C APC/C
D Ring finger protein
E K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E K03349 APC2; anaphase-promoting complex subunit 2
D target recognizing subunit
E K03363 CDC20; cell division cycle 20, cofactor of APC complex
E K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E K12782 AMA1; meiosis-specific APC/C activator protein AMA1
D other subunits
E K03348 APC1; anaphase-promoting complex subunit 1
E K03350 APC3, CDC27; anaphase-promoting complex subunit 3
E K03351 APC4; anaphase-promoting complex subunit 4
E K03352 APC5; anaphase-promoting complex subunit 5
E K03353 APC6, CDC16; anaphase-promoting complex subunit 6
E K03354 APC7; anaphase-promoting complex subunit 7
E K03355 APC8, CDC23; anaphase-promoting complex subunit 8
E K03356 APC9; anaphase-promoting complex subunit 9
E K03357 APC10, DOC1; anaphase-promoting complex subunit 10
E K03359 APC12, CDC26; anaphase-promoting complex subunit 12
E K12456 APC13; anaphase-promoting complex subunit 13
E K12416 SWM1, APC13; anaphase-promoting complex subunit SWM1
C BRCC complex
D K10605 BRCA1; breast cancer type 1 susceptibility protein
D K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
D K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3
D K10683 BARD1; BRCA1-associated RING domain protein 1 [EC:6.3.2.19]
D K12173 BRE, BRCC45; BRCA1-A complex subunit BRE
D K04482 RAD51; DNA repair protein RAD51
C KPC complex
D K12169 KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19]
D K12174 KPC2, UBAC1; Kip1 ubiquitination-promoting complex protein 2
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
D K08588 BAP1, UCHL2; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D K05609 UCHL3, YUH1; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D K05610 UCHL5, UCH37; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D K08601 CYLD, USLP2; ubiquitin thioesterase CYLD [EC:3.1.2.15]
D K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
D K11833 USP2_21; ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.1.2.15]
D K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.1.2.15]
D K11835 USP4_11_15, UBP12; ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.1.2.15]
D K11836 USP5_13, UBP14; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.1.2.15]
D K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.1.2.15]
D K11838 USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
D K11839 USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.1.2.15]
D K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.1.2.15]
D K11841 USP10, UBP3; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]
D K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.1.2.15]
D K11843 USP14, UBP6; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.1.2.15]
D K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.1.2.15]
D K11845 USP17, DUB3; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.1.2.15]
D K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.1.2.15]
D K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.1.2.15]
D K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.1.2.15]
D K11366 USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.1.2.15]
D K11849 USP25_28, UBP2; ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.1.2.15]
D K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.1.2.15]
D K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.1.2.15]
D K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.1.2.15]
D K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.1.2.15]
D K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.1.2.15]
D K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.1.2.15]
D K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.1.2.15]
D K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.1.2.15]
D K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.1.2.15]
D K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.1.2.15]
D K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.1.2.15]
D K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
D K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.1.2.15]
D K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.1.2.15]
D K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.1.2.15]
D K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.1.2.15]
C OTU
D K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.-.-]
D K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.-.-]
D K12655 OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.1.2.15]
D K11859 TNFAIP3, A20; tumor necrosis factor, alpha-induced protein 3 [EC:3.-.-.-]
D K11860 OTUD7; OTU domain-containing protein 7 [EC:3.-.-.-]
D K11861 VCPIP1, VCIP135; deubiquitinating protein VCIP135 [EC:3.4.22.-]
D K11862 ZRANB1, TRABID; ubiquitin thioesterase ZRANB1 [EC:3.1.2.-]
C MJD
D K11863 ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
D K15235 JOSD; josephin [EC:3.4.19.12]
C JAMM
D K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3
D K11865 MYSM1; protein MYSM1
D K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
D K11866 STAMBP, AMSH; STAM-binding protein [EC:3.1.2.15]
D K11867 STAMBPL1; AMSH-like protease [EC:3.1.2.15]
B UBL-specific proteases (ULPs)
C K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C K03345 SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
C K08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
C K08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
C K08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
C K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C K08597 SENP8, NEDP1, DEN1; sentrin-specific protease 8 [EC:3.4.22.68]
C K05609 UCHL3, YUH1; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C K16287 ULP1C_D; ubiquitin-like-specific protease 1C/D [EC:3.4.22.68]
C COP9 signalosome (CSN) complex
D K12175 GPS1, COPS1, CSN1; COP9 signalosome complex subunit 1
D K12176 COPS2, CSN2, TRIP15; COP9 signalosome complex subunit 2
D K12177 COPS3, CSN3; COP9 signalosome complex subunit 3
D K12178 COPS4, CSN4; COP9 signalosome complex subunit 4
D K09613 COPS5, CSN5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D K12179 COPS6, CSN6; COP9 signalosome complex subunit 6
D K12180 COPS7, CSN7; COP9 signalosome complex subunit 7
D K12181 COPS8, CSN8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 11, 2013