+F	Repair protein	KO
#<h2><a href="/kegg/kegg2.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Lactobacillus salivarius UCC118</h2>
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#<!---
#ENTRY       lsl03400
#NAME        T00337
#DEFINITION  <a href="/kegg/kegg2.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Lactobacillus salivarius UCC118
#--->
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A<b>Eukaryotic Type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      LSL_0559 ada; O6-methylguanine-DNA methyltransferase 	K00567 E2.1.1.63; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
C    BER (base exicision repair)
D      DNA glycosylases
E        LSL_1152 ung; uracil-DNA glycosylase 	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        LSL_0691 nth; endonuclease III 	K10773 NTH; endonuclease III [EC:4.2.99.18] 
D      AP endonucleases
D      Long Patch-BER factors
E        DNA polymerase delta complex
E        DNA polymerase epsilon complex
D      Short Patch-BER factors
D      Other BER factors
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
E        Cul4-DDB2 complex
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
E        Cul4-CSA complex
E        Other TCR factor
D      TFIIH complex
D      RPA (replication factor A)
D      Other NER factors
C    MMR (mismatch exicision repair)
D      Mismatch and loop recognition factors
D      MutS homologs specialized for meiosis
D      MutL homologs
D      DNA polymerase delta complex
D      RPA (replication factor A)
D      RFC (replication factor C)
D      Other MMR factors
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
D      RecA family proteins
D      Rad52 family proteins
D      Rad54 family proteins
D      RecQ family DNA helicases
D      Bloom's syndrome complex (BTR)
D      RPA (replication factor A)
D      Protein phosphatase 4
D      Other HR factors
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
D      MRX complex
D      DNA Ligase 4 complex
D      X-family DNA polymerases
D      Other NHEJ factors
C    FA (Fanconi anemia) pathway
D      FA core complex
D      FA core complex binding factors
D      Bloom's syndrome complex (BTR)
D      FANCD2-I complex
D      Downstream FA components
D      Other FA pathway factors
C    Other DSBR factors
D      Protein phosphatase 6
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    B-family DNA polymerases
C    A-family DNA polymerase
C    Rad6 epistasis group
B  Check point factors
C    Rad9-Hus1-Rad1 complex
C    HRAD17(Rad24)-RFC complex
C    Rad17-Mec3-Ddc1 complex
C    FPC (fork protection complex)
C    Other check point factors
B  Other factors with a suspected DNA repair function
C    DNA polymerases
C    Nucleases
C    PSO4 complex
C    Modulation of nucleotide pools
D      LSL_1014 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase 	K03574 MUTT; 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] 
D      LSL_1251 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase 	K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23] 
#
A<b>Prokaryotic Type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      LSL_0559 ada; O6-methylguanine-DNA methyltransferase 	K00567 E2.1.1.63; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
C    BER (base exicision repair)
D      DNA glycosylases
E        LSL_1152 ung; uracil-DNA glycosylase 	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        LSL_1082 DNA-3-methyladenine glycosylase 	K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] 
E        LSL_0489 nei; formamidopyrimidine-DNA glycosylase 	K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] 
E        LSL_0691 nth; endonuclease III 	K10773 NTH; endonuclease III [EC:4.2.99.18] 
D      AP endonucleases
E        LSL_1490 xthA; exodeoxyribonuclease III 	K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] 
D      RecJ
E        LSL_1091 recJ; single-stranded-DNA-specific exonuclease 	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] 
D      DNA ligase
E        LSL_1348 lig; NAD-dependent DNA ligase 	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
D      DNA polymerase I
E        LSL_0488 polA; DNA polymerase I 	K02335 DPO1; DNA polymerase I [EC:2.7.7.7] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        LSL_1174 uvrA; excinuclease ABC subunit A	K03701 uvrA; excinuclease ABC subunit A 
E        LSL_1175 uvrB; excinuclease ABC subunit B	K03702 uvrB; excinuclease ABC subunit B 
E        LSL_1098 uvrC; excinuclease ABC subunit C	K03703 uvrC; excinuclease ABC subunit C 
E        LSL_1349 pcrA; ATP-dependent DNA helicase 	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_1377 rep; ATP-dependent DNA helicase 	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_1564 DNA helicase	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_0488 polA; DNA polymerase I 	K02335 DPO1; DNA polymerase I [EC:2.7.7.7] 
E        LSL_1348 lig; NAD-dependent DNA ligase 	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
F          LSL_0197 rpoB; DNA-directed RNA polymerase subunit beta 	K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 
F          LSL_0198 rpoC; DNA-directed RNA polymerase subunit beta' 	K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 
F          LSL_1409 rpoA; DNA-directed RNA polymerase subunit alpha 	K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 
F          LSL_0341 rpoE; DNA-directed RNA polymerase subunit delta 	K03048 rpoE; DNA-directed RNA polymerase subunit delta 
F          LSL_0612 DNA-directed RNA polymerase subunit omega 	K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] 
E        TRCF (transcription-repair coupling factor)
F          LSL_1360 mfd; transcription-repair coupling factor	K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-] 
C    MMR (mismatch exicision repair)
D      Mismatch and loop recognition factors
E        LSL_1128 mutS; DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS 
E        LSL_1105 mutS; DNA mismatch repair protein	K07456 mutS2; DNA mismatch repair protein MutS2 
D      Molecular matchmaker
E        LSL_1127 mutL; DNA mismatch repair protein	K03572 mutL; DNA mismatch repair protein MutL 
D      Strand discrimination factor
D      DNA exonucleases
E        LSL_0534 xseA; exodeoxyribonuclease VII large subunit 	K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] 
E        LSL_0535 xseB; exodeoxyribonuclease VII small subunit 	K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] 
D      DNA polymerase III holoenzyme
E        LSL_0865 dnaE; DNA polymerase III subunit alpha 	K02337 DPO3A1; DNA polymerase III subunit alpha [EC:2.7.7.7] 
E        LSL_0567 polC; DNA polymerase III PolC 	K03763 DPO3A2; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] 
E        LSL_0002 dnaN; DNA polymerase III subunit beta 	K02338 DPO3B; DNA polymerase III subunit beta [EC:2.7.7.7] 
E        LSL_0681 holA; DNA polymerase III subunit delta 	K02340 DPO3D1; DNA polymerase III subunit delta [EC:2.7.7.7] 
E        LSL_1223 holB; DNA polymerase III subunit delta' 	K02341 DPO3D2; DNA polymerase III subunit delta' [EC:2.7.7.7] 
E        LSL_1149 dnaQ; DNA-directed DNA polymerase III subunit epsilon 	K02342 DPO3E; DNA polymerase III subunit epsilon [EC:2.7.7.7] 
E        LSL_1228 dnaX; DNA polymerase III subunit gamma/tau 	K02343 DPO3G; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] 
D      DNA ligase
E        LSL_1348 lig; NAD-dependent DNA ligase 	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] 
D      Other MMR factors
E        LSL_1349 pcrA; ATP-dependent DNA helicase 	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_1377 rep; ATP-dependent DNA helicase 	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_1564 DNA helicase	K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] 
E        LSL_0008 ssb; single-strand DNA binding protein	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
E        LSL_0728 recD; exodeoxyribonuclease V subunit alpha 	K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] 
E        LSL_1130 recA; recombinase A	K03553 recA; recombination protein RecA 
E        LSL_1126 ruvA; Holliday junction DNA helicase RuvA	K03550 ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12] 
E        LSL_1125 ruvB; Holliday junction DNA helicase RuvB 	K03551 ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12] 
E        LSL_0613b primosomal protein n-prim	K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:3.6.4.-] 
E        LSL_1369 sbcC; exonuclease 	K03546 sbcC; exonuclease SbcC 
E        LSL_1370 sbcD; exonuclease 	K03547 sbcD; exonuclease SbcD 
D      RecFOR pathway proteins
E        LSL_1130 recA; recombinase A	K03553 recA; recombination protein RecA 
E        LSL_1250 radA; DNA repair protein RadA	K04485 sms; DNA repair protein RadA/Sms 
E        LSL_0004 recF; recombination protein F	K03629 recF; DNA replication and repair protein RecF 
E        LSL_0622 recG; ATP-dependent DNA helicase 	K03655 recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12] 
E        LSL_1091 recJ; single-stranded-DNA-specific exonuclease 	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] 
E        LSL_0894 recO; DNA repair protein	K03584 recO; DNA repair protein RecO (recombination protein O) 
E        LSL_1226 recR; recombination protein RecR	K06187 recR; recombination protein RecR 
E        LSL_0539 recN; DNA repair protein	K03631 recN; DNA repair protein RecN (Recombination protein N) 
E        LSL_0932 recU; Holliday junction-specific endonuclease	K03700 recU; recombination protein U 
E        LSL_1126 ruvA; Holliday junction DNA helicase RuvA	K03550 ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12] 
E        LSL_1125 ruvB; Holliday junction DNA helicase RuvB 	K03551 ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12] 
D      AddAB pathway proteins
E        LSL_1607 ATP-dependent nuclease subunit A	K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:3.1.-.- 3.6.4.12] 
E        LSL_1608 ATP-dependent nuclease subunit B	K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:3.1.-.- 3.6.4.12] 
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
F          LSL_0006 gyrA; DNA gyrase subunit A 	K02469 gyrA; DNA gyrase subunit A [EC:5.99.1.3] 
F          LSL_0005 gyrB; DNA gyrase subunit B 	K02470 gyrB; DNA gyrase subunit B [EC:5.99.1.3] 
F          LSL_0720 topA; DNA topoisomerase I 	K03168 topA; DNA topoisomerase I [EC:5.99.1.2] 
E        Supressor
F          LSL_0885 DNA-binding protein HU	K03530 hupB; DNA-binding protein HU-beta 
F          LSL_1774 himA; DNA-binding protein HU	K03530 hupB; DNA-binding protein HU-beta 
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
F          LSL_1091 recJ; single-stranded-DNA-specific exonuclease 	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] 
F          LSL_0894 recO; DNA repair protein	K03584 recO; DNA repair protein RecO (recombination protein O) 
F          LSL_1226 recR; recombination protein RecR	K06187 recR; recombination protein RecR 
E        Facilitator
E        Supressor
F          LSL_0902 recQ; ATP-dependent DNA helicase 	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:3.6.4.12] 
F          LSL_1174 uvrA; excinuclease ABC subunit A	K03701 uvrA; excinuclease ABC subunit A 
F          LSL_1175 uvrB; excinuclease ABC subunit B	K03702 uvrB; excinuclease ABC subunit B 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      LSL_1162 dinP; DNA polymerase IV 	K02346 DPO4; DNA polymerase IV [EC:2.7.7.7] 
C    Other SOS response factors
D      LSL_1130 recA; recombinase A	K03553 recA; recombination protein RecA 
D      LSL_0540 lexA; LexA repressor 	K01356 lexA; repressor LexA [EC:3.4.21.88] 
D      LSL_0539 recN; DNA repair protein	K03631 recN; DNA repair protein RecN (Recombination protein N) 
D      LSL_0008 ssb; single-strand DNA binding protein	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
D      LSL_0686 dinG; ATP-dependent helicase DinG	K03722 dinG; ATP-dependent DNA helicase DinG [EC:3.6.4.12] 
C    Modulation of nucleotide pools
D      LSL_1014 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase 	K03574 MUTT; 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] 
D      LSL_1251 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase 	K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23] 
D      LSL_1232 nrdA; ribonucleotide-diphosphate reductase subunit alpha 	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] 
D      LSL_1233 nrdF; ribonucleotide-diphosphate reductase subunit beta 	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] 
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#Last updated: April 2, 2013
