+E Enzyme KO #

  Enzymes - Prevotella ruminicola

% # ! A1. Oxidoreductases B 1.1 Acting on the CH-OH group of donors C 1.1.1 With NAD+ or NADP+ as acceptor D 1.1.1.1 alcohol dehydrogenase D 1.1.1.2 alcohol dehydrogenase (NADP+) D 1.1.1.3 homoserine dehydrogenase E PRU_1016 thrA; aspartate kinase/homoserine dehydrogenase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D 1.1.1.4 (R,R)-butanediol dehydrogenase D 1.1.1.6 glycerol dehydrogenase D 1.1.1.7 propanediol-phosphate dehydrogenase D 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) D 1.1.1.9 D-xylulose reductase D 1.1.1.10 L-xylulose reductase D 1.1.1.11 D-arabinitol 4-dehydrogenase D 1.1.1.12 L-arabinitol 4-dehydrogenase D 1.1.1.13 L-arabinitol 2-dehydrogenase D 1.1.1.14 L-iditol 2-dehydrogenase D 1.1.1.15 D-iditol 2-dehydrogenase D 1.1.1.16 galactitol 2-dehydrogenase D 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase D 1.1.1.18 inositol 2-dehydrogenase D 1.1.1.19 glucuronate reductase D 1.1.1.20 glucuronolactone reductase D 1.1.1.21 aldehyde reductase D 1.1.1.22 UDP-glucose 6-dehydrogenase E PRU_1313 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] E PRU_1769 UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D 1.1.1.23 histidinol dehydrogenase E PRU_0389 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D 1.1.1.24 quinate dehydrogenase D 1.1.1.25 shikimate dehydrogenase E PRU_0721 shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D 1.1.1.26 glyoxylate reductase D 1.1.1.27 L-lactate dehydrogenase D 1.1.1.28 D-lactate dehydrogenase D 1.1.1.29 glycerate dehydrogenase E PRU_0689 hprA; glycerate dehydrogenase K00018 hprA; glycerate dehydrogenase [EC:1.1.1.29] D 1.1.1.30 3-hydroxybutyrate dehydrogenase D 1.1.1.31 3-hydroxyisobutyrate dehydrogenase D 1.1.1.32 mevaldate reductase D 1.1.1.33 mevaldate reductase (NADPH) D 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH) D 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase D 1.1.1.36 acetoacetyl-CoA reductase D 1.1.1.37 malate dehydrogenase E PRU_2158 malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating) D 1.1.1.39 malate dehydrogenase (decarboxylating) D 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) D 1.1.1.41 isocitrate dehydrogenase (NAD+) D 1.1.1.42 isocitrate dehydrogenase (NADP+) D 1.1.1.43 phosphogluconate 2-dehydrogenase D 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) D 1.1.1.45 L-gulonate 3-dehydrogenase D 1.1.1.46 L-arabinose 1-dehydrogenase D 1.1.1.47 glucose 1-dehydrogenase D 1.1.1.48 D-galactose 1-dehydrogenase D 1.1.1.49 glucose-6-phosphate dehydrogenase D 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (B-specific) D 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase D 1.1.1.52 3alpha-hydroxycholanate dehydrogenase D 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase D 1.1.1.54 allyl-alcohol dehydrogenase D 1.1.1.55 lactaldehyde reductase (NADPH) D 1.1.1.56 ribitol 2-dehydrogenase D 1.1.1.57 fructuronate reductase E PRU_0735 mannitol dehydrogenase family protein K00040 uxuB; fructuronate reductase [EC:1.1.1.57] D 1.1.1.58 tagaturonate reductase E PRU_1646 tagaturonate reductase K00041 uxaB; tagaturonate reductase [EC:1.1.1.58] D 1.1.1.59 3-hydroxypropionate dehydrogenase D 1.1.1.60 2-hydroxy-3-oxopropionate reductase D 1.1.1.61 4-hydroxybutyrate dehydrogenase D 1.1.1.62 17beta-estradiol 17-dehydrogenase D 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) D 1.1.1.65 pyridoxine 4-dehydrogenase D 1.1.1.66 omega-hydroxydecanoate dehydrogenase D 1.1.1.67 mannitol 2-dehydrogenase D 1.1.1.69 gluconate 5-dehydrogenase E PRU_2301 idnO; gluconate 5-dehydrogenase K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D 1.1.1.71 alcohol dehydrogenase [NAD(P)+] D 1.1.1.72 glycerol dehydrogenase (NADP+) D 1.1.1.73 octanol dehydrogenase D 1.1.1.75 (R)-aminopropanol dehydrogenase D 1.1.1.76 (S,S)-butanediol dehydrogenase D 1.1.1.77 lactaldehyde reductase D 1.1.1.78 methylglyoxal reductase (NADH-dependent) D 1.1.1.79 glyoxylate reductase (NADP+) D 1.1.1.80 isopropanol dehydrogenase (NADP+) D 1.1.1.81 hydroxypyruvate reductase D 1.1.1.82 malate dehydrogenase (NADP+) D 1.1.1.83 D-malate dehydrogenase (decarboxylating) D 1.1.1.84 dimethylmalate dehydrogenase D 1.1.1.85 3-isopropylmalate dehydrogenase E PRU_0733 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D 1.1.1.86 ketol-acid reductoisomerase E PRU_0551 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D 1.1.1.87 homoisocitrate dehydrogenase D 1.1.1.88 hydroxymethylglutaryl-CoA reductase D 1.1.1.90 aryl-alcohol dehydrogenase D 1.1.1.91 aryl-alcohol dehydrogenase (NADP+) D 1.1.1.92 oxaloglycolate reductase (decarboxylating) D 1.1.1.93 tartrate dehydrogenase D 1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+] E PRU_1692 glycerol-3-phosphate dehydrogenase K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D 1.1.1.95 phosphoglycerate dehydrogenase E PRU_1036 serA; D-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] D 1.1.1.96 diiodophenylpyruvate reductase D 1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase D 1.1.1.98 (R)-2-hydroxy-fatty-acid dehydrogenase D 1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase D 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase E PRU_0297 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D 1.1.1.101 acylglycerone-phosphate reductase D 1.1.1.102 3-dehydrosphinganine reductase D 1.1.1.103 L-threonine 3-dehydrogenase D 1.1.1.104 4-oxoproline reductase D 1.1.1.105 all-trans-retinol dehydrogenase (NAD+) D 1.1.1.106 pantoate 4-dehydrogenase D 1.1.1.107 pyridoxal 4-dehydrogenase D 1.1.1.108 carnitine 3-dehydrogenase D 1.1.1.110 indolelactate dehydrogenase D 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase D 1.1.1.112 indanol dehydrogenase D 1.1.1.113 L-xylose 1-dehydrogenase D 1.1.1.114 apiose 1-reductase D 1.1.1.115 ribose 1-dehydrogenase (NADP+) D 1.1.1.116 D-arabinose 1-dehydrogenase (NAD+) D 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+] D 1.1.1.118 glucose 1-dehydrogenase (NAD+) D 1.1.1.119 glucose 1-dehydrogenase (NADP+) D 1.1.1.120 galactose 1-dehydrogenase (NADP+) D 1.1.1.121 aldose 1-dehydrogenase (NAD+) D 1.1.1.122 D-threo-aldose 1-dehydrogenase D 1.1.1.123 sorbose 5-dehydrogenase (NADP+) D 1.1.1.124 fructose 5-dehydrogenase (NADP+) D 1.1.1.125 2-deoxy-D-gluconate 3-dehydrogenase D 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase D 1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase D 1.1.1.129 L-threonate 3-dehydrogenase D 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase D 1.1.1.131 mannuronate reductase D 1.1.1.132 GDP-mannose 6-dehydrogenase D 1.1.1.133 dTDP-4-dehydrorhamnose reductase E PRU_0238 rfbD; dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133] D 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+) D 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase D 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase D 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase D 1.1.1.138 mannitol 2-dehydrogenase (NADP+) D 1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase D 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) D 1.1.1.142 D-pinitol dehydrogenase D 1.1.1.143 sequoyitol dehydrogenase D 1.1.1.144 perillyl-alcohol dehydrogenase D 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase D 1.1.1.146 11beta-hydroxysteroid dehydrogenase D 1.1.1.147 16alpha-hydroxysteroid dehydrogenase D 1.1.1.148 estradiol 17alpha-dehydrogenase D 1.1.1.149 20alpha-hydroxysteroid dehydrogenase D 1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+) D 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+) D 1.1.1.152 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase D 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) D 1.1.1.154 ureidoglycolate dehydrogenase D 1.1.1.156 glycerol 2-dehydrogenase (NADP+) D 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase D 1.1.1.159 7alpha-hydroxysteroid dehydrogenase D 1.1.1.160 dihydrobunolol dehydrogenase D 1.1.1.162 erythrulose reductase D 1.1.1.163 cyclopentanol dehydrogenase D 1.1.1.164 hexadecanol dehydrogenase D 1.1.1.165 2-alkyn-1-ol dehydrogenase D 1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase D 1.1.1.167 hydroxymalonate dehydrogenase D 1.1.1.168 2-dehydropantolactone reductase (A-specific) D 1.1.1.169 2-dehydropantoate 2-reductase E PRU_1142 panE; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) D 1.1.1.172 2-oxoadipate reductase D 1.1.1.173 L-rhamnose 1-dehydrogenase D 1.1.1.174 cyclohexane-1,2-diol dehydrogenase D 1.1.1.175 D-xylose 1-dehydrogenase D 1.1.1.176 12alpha-hydroxysteroid dehydrogenase D 1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+) D 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase D 1.1.1.179 D-xylose 1-dehydrogenase (NADP+) D 1.1.1.181 cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase D 1.1.1.183 geraniol dehydrogenase (NADP+) D 1.1.1.184 carbonyl reductase (NADPH) D 1.1.1.185 L-glycol dehydrogenase D 1.1.1.186 dTDP-galactose 6-dehydrogenase D 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase D 1.1.1.188 prostaglandin-F synthase D 1.1.1.189 prostaglandin-E2 9-reductase D 1.1.1.190 indole-3-acetaldehyde reductase (NADH) D 1.1.1.191 indole-3-acetaldehyde reductase (NADPH) D 1.1.1.192 long-chain-alcohol dehydrogenase D 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase E PRU_2399 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D 1.1.1.194 coniferyl-alcohol dehydrogenase D 1.1.1.195 cinnamyl-alcohol dehydrogenase D 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+) D 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+) D 1.1.1.198 (+)-borneol dehydrogenase D 1.1.1.199 (S)-usnate reductase D 1.1.1.200 aldose-6-phosphate reductase (NADPH) D 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+) D 1.1.1.202 1,3-propanediol dehydrogenase D 1.1.1.203 uronate dehydrogenase D 1.1.1.205 IMP dehydrogenase E PRU_0032 guaB; inosine-5'-monophosphate dehydrogenase K00088 E1.1.1.205; IMP dehydrogenase [EC:1.1.1.205] D 1.1.1.206 tropinone reductase I D 1.1.1.207 (-)-menthol dehydrogenase D 1.1.1.208 (+)-neomenthol dehydrogenase D 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase D 1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase D 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase D 1.1.1.212 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) D 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (A-specific) D 1.1.1.214 2-dehydropantolactone reductase (B-specific) D 1.1.1.215 gluconate 2-dehydrogenase D 1.1.1.216 farnesol dehydrogenase (NADP+) D 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase D 1.1.1.218 morphine 6-dehydrogenase D 1.1.1.219 dihydrokaempferol 4-reductase D 1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase D 1.1.1.221 vomifoliol dehydrogenase D 1.1.1.222 (R)-4-hydroxyphenyllactate dehydrogenase D 1.1.1.223 isopiperitenol dehydrogenase D 1.1.1.224 mannose-6-phosphate 6-reductase D 1.1.1.225 chlordecone reductase D 1.1.1.226 4-hydroxycyclohexanecarboxylate dehydrogenase D 1.1.1.227 (-)-borneol dehydrogenase D 1.1.1.228 (+)-sabinol dehydrogenase D 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase D 1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase D 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+) D 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase D 1.1.1.233 N-acylmannosamine 1-dehydrogenase D 1.1.1.234 flavanone 4-reductase D 1.1.1.235 8-oxocoformycin reductase D 1.1.1.236 tropinone reductase II D 1.1.1.237 hydroxyphenylpyruvate reductase D 1.1.1.238 12beta-hydroxysteroid dehydrogenase D 1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) D 1.1.1.240 N-acetylhexosamine 1-dehydrogenase D 1.1.1.241 6-endo-hydroxycineole dehydrogenase D 1.1.1.243 carveol dehydrogenase D 1.1.1.244 methanol dehydrogenase D 1.1.1.245 cyclohexanol dehydrogenase D 1.1.1.246 pterocarpin synthase D 1.1.1.247 codeinone reductase (NADPH) D 1.1.1.248 salutaridine reductase (NADPH) D 1.1.1.250 D-arabinitol 2-dehydrogenase D 1.1.1.251 galactitol-1-phosphate 5-dehydrogenase D 1.1.1.252 tetrahydroxynaphthalene reductase D 1.1.1.254 (S)-carnitine 3-dehydrogenase D 1.1.1.255 mannitol dehydrogenase D 1.1.1.256 fluoren-9-ol dehydrogenase D 1.1.1.257 4-(hydroxymethyl)benzenesulfonate dehydrogenase D 1.1.1.258 6-hydroxyhexanoate dehydrogenase D 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase D 1.1.1.260 sulcatone reductase D 1.1.1.261 sn-glycerol-1-phosphate dehydrogenase D 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase E PRU_1561 4-hydroxythreonine-4-phosphate dehydrogenase K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D 1.1.1.263 1,5-anhydro-D-fructose reductase D 1.1.1.264 L-idonate 5-dehydrogenase D 1.1.1.265 3-methylbutanal reductase D 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase D 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase E PRU_2925 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase D 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase D 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase D 1.1.1.271 GDP-L-fucose synthase E PRU_1378 fcl; GDP-L-fucose synthase K02377 E1.1.1.271; GDP-L-fucose synthase [EC:1.1.1.271] D 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+) D 1.1.1.273 vellosimine dehydrogenase D 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) D 1.1.1.275 (+)-trans-carveol dehydrogenase D 1.1.1.276 serine 3-dehydrogenase D 1.1.1.277 3beta-hydroxy-5beta-steroid dehydrogenase D 1.1.1.278 3beta-hydroxy-5alpha-steroid dehydrogenase D 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase D 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase D 1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase D 1.1.1.282 quinate/shikimate dehydrogenase D 1.1.1.283 methylglyoxal reductase (NADPH-dependent) D 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase D 1.1.1.285 3''-deamino-3''-oxonicotianamine reductase D 1.1.1.286 isocitrate---homoisocitrate dehydrogenase D 1.1.1.287 D-arabinitol dehydrogenase (NADP+) D 1.1.1.288 xanthoxin dehydrogenase D 1.1.1.289 sorbose reductase D 1.1.1.290 4-phosphoerythronate dehydrogenase D 1.1.1.291 2-hydroxymethylglutarate dehydrogenase D 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) D 1.1.1.294 chlorophyll(ide) b reductase D 1.1.1.295 momilactone-A synthase D 1.1.1.296 dihydrocarveol dehydrogenase D 1.1.1.297 limonene-1,2-diol dehydrogenase D 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+) D 1.1.1.299 malate dehydrogenase [NAD(P)+] D 1.1.1.300 NADP-retinol dehydrogenase D 1.1.1.301 D-arabitol-phosphate dehydrogenase D 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase D 1.1.1.303 diacetyl reductase [(R)-acetoin forming] D 1.1.1.304 diacetyl reductase [(S)-acetoin forming] D 1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) D 1.1.1.306 S-(hydroxymethyl)mycothiol dehydrogenase D 1.1.1.307 D-xylose reductase D 1.1.1.308 sulfopropanediol 3-dehydrogenase D 1.1.1.309 phosphonoacetaldehyde reductase (NADH) D 1.1.1.310 (S)-sulfolactate dehydrogenase D 1.1.1.311 (S)-1-phenylethanol dehydrogenase D 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase D 1.1.1.313 sulfoacetaldehyde reductase D 1.1.1.314 germacrene A alcohol dehydrogenase D 1.1.1.315 11-cis-retinol dehydrogenase D 1.1.1.316 L-galactose 1-dehydrogenase D 1.1.1.317 perakine reductase D 1.1.1.318 eugenol synthase D 1.1.1.319 isoeugenol synthase D 1.1.1.320 benzil reductase [(S)-benzoin forming] D 1.1.1.321 benzil reductase [(R)-benzoin forming] D 1.1.1.322 (-)-endo-fenchol dehydrogenase D 1.1.1.323 (+)-thujan-3-ol dehydrogenase D 1.1.1.324 8-hydroxygeraniol dehydrogenase D 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) D 1.1.1.326 zerumbone synthase D 1.1.1.327 5-exo-hydroxycamphor dehydrogenase D 1.1.1.328 nicotine blue oxidoreductase D 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase D 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase D 1.1.1.331 secoisolariciresinol dehydrogenase D 1.1.1.332 chanoclavine-I dehydrogenase D 1.1.1.333 decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase D 1.1.1.334 methylecgonone reductase D 1.1.1.335 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase D 1.1.1.336 UDP-N-acetyl-D-mannosamine dehydrogenase D 1.1.1.337 L-2-hydroxycarboxylate dehydrogenase (NAD+) D 1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+) D 1.1.1.339 dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) D 1.1.1.340 1-deoxy-11beta-hydroxypentalenate dehydrogenase D 1.1.1.341 CDP-abequose synthase D 1.1.1.342 CDP-paratose synthase D 1.1.1.343 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) D 1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+] D 1.1.1.345 D-2-hydroxyacid dehydrogenase (NAD+) D 1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) D 1.1.1.- C 1.1.2 With a cytochrome as acceptor D 1.1.2.2 mannitol dehydrogenase (cytochrome) D 1.1.2.3 L-lactate dehydrogenase (cytochrome) D 1.1.2.4 D-lactate dehydrogenase (cytochrome) D 1.1.2.5 D-lactate dehydrogenase (cytochrome c-553) D 1.1.2.6 polyvinyl alcohol dehydrogenase (cytochrome) D 1.1.2.7 methanol dehydrogenase (cytochrome c) D 1.1.2.8 alcohol dehydrogenase (cytochrome c) D 1.1.2.- C 1.1.3 With oxygen as acceptor D 1.1.3.3 malate oxidase D 1.1.3.4 glucose oxidase D 1.1.3.5 hexose oxidase D 1.1.3.6 cholesterol oxidase D 1.1.3.7 aryl-alcohol oxidase D 1.1.3.8 L-gulonolactone oxidase D 1.1.3.9 galactose oxidase D 1.1.3.10 pyranose oxidase D 1.1.3.11 L-sorbose oxidase D 1.1.3.12 pyridoxine 4-oxidase D 1.1.3.13 alcohol oxidase D 1.1.3.14 catechol oxidase (dimerizing) D 1.1.3.15 (S)-2-hydroxy-acid oxidase D 1.1.3.16 ecdysone oxidase D 1.1.3.17 choline oxidase D 1.1.3.18 secondary-alcohol oxidase D 1.1.3.19 4-hydroxymandelate oxidase D 1.1.3.20 long-chain-alcohol oxidase D 1.1.3.21 glycerol-3-phosphate oxidase D 1.1.3.23 thiamine oxidase D 1.1.3.27 hydroxyphytanate oxidase D 1.1.3.28 nucleoside oxidase D 1.1.3.29 N-acylhexosamine oxidase D 1.1.3.30 polyvinyl-alcohol oxidase D 1.1.3.37 D-arabinono-1,4-lactone oxidase D 1.1.3.38 vanillyl-alcohol oxidase D 1.1.3.39 nucleoside oxidase (H2O2-forming) D 1.1.3.40 D-mannitol oxidase D 1.1.3.41 alditol oxidase D 1.1.3.42 prosolanapyrone-II oxidase D 1.1.3.43 paromamine 6'-oxidase D 1.1.3.44 6'''-hydroxyneomycin C oxidase D 1.1.3.- C 1.1.4 With a disulfide as acceptor D 1.1.4.1 vitamin-K-epoxide reductase (warfarin-sensitive) D 1.1.4.2 vitamin-K-epoxide reductase (warfarin-insensitive) C 1.1.5 With a quinone or similar compound as acceptor D 1.1.5.2 quinoprotein glucose dehydrogenase D 1.1.5.3 glycerol-3-phosphate dehydrogenase D 1.1.5.4 malate dehydrogenase (quinone) D 1.1.5.5 alcohol dehydrogenase (quinone) D 1.1.5.6 formate dehydrogenase-N D 1.1.5.7 cyclic alcohol dehydrogenase (quinone) D 1.1.5.8 quinate dehydrogenase (quinone) C 1.1.9 With a copper protein as acceptor D 1.1.9.1 alcohol dehydrogenase (azurin) C 1.1.98 With other, known, acceptors D 1.1.98.2 glucose-6-phosphate dehydrogenase (coenzyme-F420) D 1.1.98.3 decaprenylphospho-beta-D-ribofuranose 2-oxidase C 1.1.99 With other acceptors D 1.1.99.1 choline dehydrogenase D 1.1.99.2 2-hydroxyglutarate dehydrogenase D 1.1.99.3 gluconate 2-dehydrogenase (acceptor) D 1.1.99.4 dehydrogluconate dehydrogenase D 1.1.99.6 D-2-hydroxy-acid dehydrogenase D 1.1.99.7 lactate---malate transhydrogenase D 1.1.99.9 pyridoxine 5-dehydrogenase D 1.1.99.10 glucose dehydrogenase (acceptor) D 1.1.99.11 fructose 5-dehydrogenase D 1.1.99.12 sorbose dehydrogenase D 1.1.99.13 glucoside 3-dehydrogenase D 1.1.99.14 glycolate dehydrogenase D 1.1.99.18 cellobiose dehydrogenase (acceptor) D 1.1.99.20 alkan-1-ol dehydrogenase (acceptor) D 1.1.99.21 D-sorbitol dehydrogenase (acceptor) D 1.1.99.22 glycerol dehydrogenase (acceptor) D 1.1.99.24 hydroxyacid-oxoacid transhydrogenase D 1.1.99.26 3-hydroxycyclohexanone dehydrogenase D 1.1.99.27 (R)-pantolactone dehydrogenase (flavin) D 1.1.99.28 glucose-fructose oxidoreductase D 1.1.99.29 pyranose dehydrogenase (acceptor) D 1.1.99.30 2-oxo-acid reductase D 1.1.99.31 (S)-mandelate dehydrogenase D 1.1.99.32 L-sorbose 1-dehydrogenase D 1.1.99.33 formate dehydrogenase (acceptor) D 1.1.99.35 soluble quinoprotein glucose dehydrogenase D 1.1.99.36 alcohol dehydrogenase (nicotinoprotein) D 1.1.99.37 methanol dehydrogenase (nicotinoprotein) D 1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent) D 1.1.99.- C 1.1.- Acting on the CH-OH group of donors D 1.1.-.- B 1.2 Acting on the aldehyde or oxo group of donors C 1.2.1 With NAD+ or NADP+ as acceptor D 1.2.1.2 formate dehydrogenase D 1.2.1.3 aldehyde dehydrogenase (NAD+) D 1.2.1.4 aldehyde dehydrogenase (NADP+) D 1.2.1.5 aldehyde dehydrogenase [NAD(P)+] D 1.2.1.7 benzaldehyde dehydrogenase (NADP+) D 1.2.1.8 betaine-aldehyde dehydrogenase D 1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+) D 1.2.1.10 acetaldehyde dehydrogenase (acetylating) D 1.2.1.11 aspartate-semialdehyde dehydrogenase E PRU_0050 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) E PRU_1674 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] D 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) D 1.2.1.15 malonate-semialdehyde dehydrogenase D 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+] D 1.2.1.17 glyoxylate dehydrogenase (acylating) D 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating) D 1.2.1.19 aminobutyraldehyde dehydrogenase D 1.2.1.20 glutarate-semialdehyde dehydrogenase D 1.2.1.21 glycolaldehyde dehydrogenase D 1.2.1.22 lactaldehyde dehydrogenase D 1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+) D 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+) D 1.2.1.25 2-oxoisovalerate dehydrogenase (acylating) D 1.2.1.26 2,5-dioxovalerate dehydrogenase D 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (acylating) D 1.2.1.28 benzaldehyde dehydrogenase (NAD+) D 1.2.1.29 aryl-aldehyde dehydrogenase D 1.2.1.30 aryl-aldehyde dehydrogenase (NADP+) D 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase D 1.2.1.32 aminomuconate-semialdehyde dehydrogenase D 1.2.1.33 (R)-dehydropantoate dehydrogenase D 1.2.1.36 retinal dehydrogenase D 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase E PRU_2200 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D 1.2.1.39 phenylacetaldehyde dehydrogenase D 1.2.1.41 glutamate-5-semialdehyde dehydrogenase E PRU_2208 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] D 1.2.1.42 hexadecanal dehydrogenase (acylating) D 1.2.1.43 formate dehydrogenase (NADP+) D 1.2.1.44 cinnamoyl-CoA reductase D 1.2.1.46 formaldehyde dehydrogenase D 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase D 1.2.1.48 long-chain-aldehyde dehydrogenase D 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+) D 1.2.1.50 long-chain-fatty-acyl-CoA reductase D 1.2.1.51 pyruvate dehydrogenase (NADP+) D 1.2.1.52 oxoglutarate dehydrogenase (NADP+) D 1.2.1.53 4-hydroxyphenylacetaldehyde dehydrogenase D 1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase D 1.2.1.57 butanal dehydrogenase D 1.2.1.58 phenylglyoxylate dehydrogenase (acylating) D 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) D 1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase D 1.2.1.61 4-hydroxymuconic-semialdehyde dehydrogenase D 1.2.1.62 4-formylbenzenesulfonate dehydrogenase D 1.2.1.63 6-oxohexanoate dehydrogenase D 1.2.1.64 4-hydroxybenzaldehyde dehydrogenase D 1.2.1.65 salicylaldehyde dehydrogenase D 1.2.1.67 vanillin dehydrogenase D 1.2.1.68 coniferyl-aldehyde dehydrogenase D 1.2.1.69 fluoroacetaldehyde dehydrogenase D 1.2.1.70 glutamyl-tRNA reductase D 1.2.1.71 succinylglutamate-semialdehyde dehydrogenase D 1.2.1.72 erythrose-4-phosphate dehydrogenase D 1.2.1.73 sulfoacetaldehyde dehydrogenase D 1.2.1.74 abieta-7,13-dien-18-al dehydrogenase D 1.2.1.75 malonyl CoA reductase (malonate semialdehyde-forming) D 1.2.1.76 succinate-semialdehyde dehydrogenase (acylating) D 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) D 1.2.1.78 2-formylbenzoate dehydrogenase D 1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+) D 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase D 1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating) D 1.2.1.82 beta-apo-4'-carotenal oxygenase D 1.2.1.83 3-succinoylsemialdehyde-pyridine dehydrogenase D 1.2.1.84 alcohol-forming fatty acyl-CoA reductase D 1.2.1.85 2-hydroxymuconate-6-semialdehyde dehydrogenase D 1.2.1.86 geranial dehydrogenase D 1.2.1.- C 1.2.2 With a cytochrome as acceptor D 1.2.2.1 formate dehydrogenase (cytochrome) D 1.2.2.3 formate dehydrogenase (cytochrome-c-553) D 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome b-561) C 1.2.3 With oxygen as acceptor D 1.2.3.1 aldehyde oxidase D 1.2.3.3 pyruvate oxidase D 1.2.3.4 oxalate oxidase D 1.2.3.5 glyoxylate oxidase D 1.2.3.6 pyruvate oxidase (CoA-acetylating) D 1.2.3.7 indole-3-acetaldehyde oxidase D 1.2.3.8 pyridoxal oxidase D 1.2.3.9 aryl-aldehyde oxidase D 1.2.3.13 4-hydroxyphenylpyruvate oxidase D 1.2.3.14 abscisic-aldehyde oxidase D 1.2.3.- C 1.2.4 With a disulfide as acceptor D 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) D 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring) D 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) D 1.2.4.- C 1.2.5 With a quinone or similar compound as acceptor D 1.2.5.1 pyruvate dehydrogenase (quinone) C 1.2.7 With an iron-sulfur protein as acceptor D 1.2.7.1 pyruvate synthase D 1.2.7.2 2-oxobutyrate synthase D 1.2.7.3 2-oxoglutarate synthase E PRU_2267 keto/oxoacid ferredoxin oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3] E PRU_1149 keto/oxoacid ferredoxin oxidoreductase subunit alpha K00174 korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3] E PRU_2268 keto/oxoacid ferredoxin oxidoreductase subunit beta K00175 korB; 2-oxoglutarate ferredoxin oxidoreductase subunit beta [EC:1.2.7.3] E PRU_1150 ferridoxin oxidoreductase K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] E PRU_1147 keto/oxoacid ferredoxin oxidoreductase subunit gamma K00177 korG; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] D 1.2.7.4 carbon-monoxide dehydrogenase (ferredoxin) D 1.2.7.5 aldehyde ferredoxin oxidoreductase D 1.2.7.6 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) D 1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) D 1.2.7.8 indolepyruvate ferredoxin oxidoreductase E PRU_1025 indolepyruvate oxidoreductase subunit alpha K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] E PRU_1024 indolepyruvate oxidoreductase subunit beta K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] D 1.2.7.10 oxalate oxidoreductase D 1.2.7.- E PRU_1235 nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K03737 nifJ; putative pyruvate-flavodoxin oxidoreductase [EC:1.2.7.-] C 1.2.99 With other acceptors D 1.2.99.2 carbon-monoxide dehydrogenase (acceptor) D 1.2.99.3 aldehyde dehydrogenase (pyrroloquinoline-quinone) D 1.2.99.4 formaldehyde dismutase D 1.2.99.5 formylmethanofuran dehydrogenase D 1.2.99.6 carboxylate reductase D 1.2.99.7 aldehyde dehydrogenase (FAD-independent) C 1.2.- Acting on the aldehyde or oxo group of donors D 1.2.-.- B 1.3 Acting on the CH-CH group of donors C 1.3.1 With NAD+ or NADP+ as acceptor D 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+) D 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+) D 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase D 1.3.1.5 cucurbitacin Delta23-reductase D 1.3.1.6 fumarate reductase (NADH) D 1.3.1.7 meso-tartrate dehydrogenase D 1.3.1.8 acyl-CoA dehydrogenase (NADP+) D 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH) D 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) D 1.3.1.11 2-coumarate reductase D 1.3.1.12 prephenate dehydrogenase D 1.3.1.13 prephenate dehydrogenase (NADP+) D 1.3.1.14 dihydroorotate dehydrogenase (NAD+) D 1.3.1.15 dihydroorotate dehydrogenase (NADP+) D 1.3.1.16 beta-nitroacrylate reductase D 1.3.1.17 3-methyleneoxindole reductase D 1.3.1.18 kynurenate-7,8-dihydrodiol dehydrogenase D 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase D 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase D 1.3.1.21 7-dehydrocholesterol reductase D 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) D 1.3.1.24 biliverdin reductase D 1.3.1.25 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase D 1.3.1.27 2-hexadecenal reductase D 1.3.1.28 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase D 1.3.1.29 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase D 1.3.1.31 2-enoate reductase D 1.3.1.32 maleylacetate reductase D 1.3.1.33 protochlorophyllide reductase D 1.3.1.34 2,4-dienoyl-CoA reductase (NADPH) D 1.3.1.35 phosphatidylcholine desaturase D 1.3.1.36 geissoschizine dehydrogenase D 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) D 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) D 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) D 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase D 1.3.1.41 xanthommatin reductase D 1.3.1.42 12-oxophytodienoate reductase D 1.3.1.43 arogenate dehydrogenase D 1.3.1.44 trans-2-enoyl-CoA reductase (NAD+) D 1.3.1.45 2'-hydroxyisoflavone reductase D 1.3.1.46 biochanin-A reductase D 1.3.1.47 alpha-santonin 1,2-reductase D 1.3.1.48 15-oxoprostaglandin 13-oxidase D 1.3.1.49 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase D 1.3.1.51 2'-hydroxydaidzein reductase D 1.3.1.53 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase D 1.3.1.54 precorrin-6A reductase D 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase D 1.3.1.57 phloroglucinol reductase D 1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase D 1.3.1.60 dibenzothiophene dihydrodiol dehydrogenase D 1.3.1.62 pimeloyl-CoA dehydrogenase D 1.3.1.63 2,4-dichlorobenzoyl-CoA reductase D 1.3.1.64 phthalate 4,5-cis-dihydrodiol dehydrogenase D 1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase D 1.3.1.66 cis-dihydroethylcatechol dehydrogenase D 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase D 1.3.1.68 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase D 1.3.1.69 zeatin reductase D 1.3.1.70 Delta14-sterol reductase D 1.3.1.71 Delta24(241)-sterol reductase D 1.3.1.72 Delta24-sterol reductase D 1.3.1.73 1,2-dihydrovomilenine reductase D 1.3.1.74 2-alkenal reductase D 1.3.1.75 divinyl chlorophyllide a 8-vinyl-reductase D 1.3.1.76 precorrin-2 dehydrogenase D 1.3.1.77 anthocyanidin reductase D 1.3.1.78 arogenate dehydrogenase (NADP+) D 1.3.1.79 arogenate dehydrogenase [NAD(P)+] D 1.3.1.80 red chlorophyll catabolite reductase D 1.3.1.81 (+)-pulegone reductase D 1.3.1.82 (-)-isopiperitenone reductase D 1.3.1.83 geranylgeranyl diphosphate reductase D 1.3.1.84 acrylyl-CoA reductase (NADPH) D 1.3.1.85 crotonyl-CoA carboxylase/reductase D 1.3.1.86 crotonyl-CoA reductase D 1.3.1.87 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase D 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+] D 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+] D 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+] D 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+] D 1.3.1.92 artemisinic aldehyde Delta11(13)-reductase D 1.3.1.93 very-long-chain enoyl-CoA reductase D 1.3.1.94 polyprenol reductase D 1.3.1.95 acrylyl-CoA reductase (NADH) D 1.3.1.96 Botryococcus squalene synthase D 1.3.1.97 botryococcene synthase D 1.3.1.98 UDP-N-acetylmuramate dehydrogenase E PRU_0584 murB; UDP-N-acetylmuramate dehydrogenase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D 1.3.1.99 iridoid synthase D 1.3.1.- C 1.3.2 With a cytochrome as acceptor D 1.3.2.3 L-galactonolactone dehydrogenase C 1.3.3 With oxygen as acceptor D 1.3.3.3 coproporphyrinogen oxidase D 1.3.3.4 protoporphyrinogen oxidase E PRU_2785 hemG; protoporphyrinogen oxidase K00231 PPOX; oxygen-dependent protoporphyrinogen oxidase [EC:1.3.3.4] D 1.3.3.5 bilirubin oxidase D 1.3.3.6 acyl-CoA oxidase D 1.3.3.7 dihydrouracil oxidase D 1.3.3.8 tetrahydroberberine oxidase D 1.3.3.9 secologanin synthase D 1.3.3.10 tryptophan alpha,beta-oxidase D 1.3.3.11 pyrroloquinoline-quinone synthase D 1.3.3.12 L-galactonolactone oxidase D 1.3.3.- C 1.3.5 With a quinone or related compound as acceptor D 1.3.5.1 succinate dehydrogenase (ubiquinone) D 1.3.5.2 dihydroorotate dehydrogenase (quinone) D 1.3.5.3 protoporphyrinogen IX dehydrogenase (menaquinone) D 1.3.5.4 fumarate reductase (menaquinone) D 1.3.5.5 15-cis-phytoene desaturase D 1.3.5.6 9,9'-dicis-zeta-carotene desaturase C 1.3.7 With an iron-sulfur protein as acceptor D 1.3.7.1 6-hydroxynicotinate reductase D 1.3.7.2 15,16-dihydrobiliverdin:ferredoxin oxidoreductase D 1.3.7.3 phycoerythrobilin:ferredoxin oxidoreductase D 1.3.7.4 phytochromobilin:ferredoxin oxidoreductase D 1.3.7.5 phycocyanobilin:ferredoxin oxidoreductase D 1.3.7.6 phycoerythrobilin synthase D 1.3.7.7 ferredoxin:protochlorophyllide reductase (ATP-dependent) D 1.3.7.8 benzoyl-CoA reductase D 1.3.7.9 4-hydroxybenzoyl-CoA reductase D 1.3.7.10 pentalenolactone synthase C 1.3.8 With a flavin as acceptor D 1.3.8.1 short-chain acyl-CoA dehydrogenase D 1.3.8.2 4,4'-diapophytoene desaturase D 1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase D 1.3.8.4 isovaleryl-CoA dehydrogenase D 1.3.8.5 2-methyl-branched-chain-enoyl-CoA reductase D 1.3.8.6 glutaryl-CoA dehydrogenase D 1.3.8.7 medium-chain acyl-CoA dehydrogenase D 1.3.8.8 long-chain acyl-CoA dehydrogenase D 1.3.8.9 very-long-chain acyl-CoA dehydrogenase C 1.3.98 With other, known, acceptors D 1.3.98.1 dihydroorotate dehydrogenase (fumarate) E PRU_0543 pyrD; dihydroorotate oxidase, catalytic subunit K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1] C 1.3.99 With other acceptors D 1.3.99.1 succinate dehydrogenase E PRU_2432 succinate dehydrogenase/fumarate reductase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1] E PRU_2431 succinate dehydrogenase/fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1] D 1.3.99.4 3-oxosteroid 1-dehydrogenase D 1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) D 1.3.99.6 3-oxo-5beta-steroid 4-dehydrogenase D 1.3.99.8 2-furoyl-CoA dehydrogenase D 1.3.99.12 2-methylacyl-CoA dehydrogenase D 1.3.99.14 cyclohexanone dehydrogenase D 1.3.99.16 isoquinoline 1-oxidoreductase D 1.3.99.17 quinoline 2-oxidoreductase D 1.3.99.18 quinaldate 4-oxidoreductase D 1.3.99.19 quinoline-4-carboxylate 2-oxidoreductase D 1.3.99.22 coproporphyrinogen dehydrogenase E PRU_0612 oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.99.22] E PRU_2784 hemN; coproporphyrinogen dehydrogenase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.99.22] D 1.3.99.23 all-trans-retinol 13,14-reductase D 1.3.99.24 2-amino-4-deoxychorismate dehydrogenase D 1.3.99.25 carvone reductase D 1.3.99.26 all-trans-zeta-carotene desaturase D 1.3.99.27 1-hydroxycarotenoid 3,4-desaturase D 1.3.99.28 phytoene desaturase (neurosporene-forming) D 1.3.99.29 phytoene desaturase (zeta-carotene-forming) D 1.3.99.30 phytoene desaturase (3,4-didehydrolycopene-forming) D 1.3.99.31 phytoene desaturase (lycopene-forming) D 1.3.99.32 glutaryl-CoA dehydrogenase (non-decarboxylating) D 1.3.99.- C 1.3.- Acting on the CH-CH group of donors D 1.3.-.- B 1.4 Acting on the CH-NH2 group of donors C 1.4.1 With NAD+ or NADP+ as acceptor D 1.4.1.1 alanine dehydrogenase E PRU_2067 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1] D 1.4.1.2 glutamate dehydrogenase D 1.4.1.3 glutamate dehydrogenase [NAD(P)+] D 1.4.1.4 glutamate dehydrogenase (NADP+) E PRU_2084 glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] E PRU_1214 gdhA; glutamate dehydrogenase, NADP-specific K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D 1.4.1.5 L-amino-acid dehydrogenase D 1.4.1.7 serine 2-dehydrogenase D 1.4.1.8 valine dehydrogenase (NADP+) D 1.4.1.9 leucine dehydrogenase D 1.4.1.10 glycine dehydrogenase D 1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase D 1.4.1.12 2,4-diaminopentanoate dehydrogenase D 1.4.1.13 glutamate synthase (NADPH) E PRU_1960 gltA_2; glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH/NADH) large chain [EC:1.4.1.13 1.4.1.14] E PRU_0699 gltA_1; glutamate synthase K00266 gltD; glutamate synthase (NADPH/NADH) small chain [EC:1.4.1.13 1.4.1.14] E PRU_1959 gltD; glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH/NADH) small chain [EC:1.4.1.13 1.4.1.14] D 1.4.1.14 glutamate synthase (NADH) E PRU_1960 gltA_2; glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH/NADH) large chain [EC:1.4.1.13 1.4.1.14] E PRU_0699 gltA_1; glutamate synthase K00266 gltD; glutamate synthase (NADPH/NADH) small chain [EC:1.4.1.13 1.4.1.14] E PRU_1959 gltD; glutamate synthase small subunit K00266 gltD; glutamate synthase (NADPH/NADH) small chain [EC:1.4.1.13 1.4.1.14] D 1.4.1.15 lysine dehydrogenase D 1.4.1.16 diaminopimelate dehydrogenase E PRU_2042 diaminopimelate dehydrogenase K03340 E1.4.1.16; diaminopimelate dehydrogenase [EC:1.4.1.16] D 1.4.1.17 N-methylalanine dehydrogenase D 1.4.1.18 lysine 6-dehydrogenase D 1.4.1.19 tryptophan dehydrogenase D 1.4.1.20 phenylalanine dehydrogenase D 1.4.1.21 aspartate dehydrogenase D 1.4.1.23 valine dehydrogenase (NAD+) D 1.4.1.24 3-dehydroquinate synthase II D 1.4.1.- C 1.4.2 With a cytochrome as acceptor D 1.4.2.1 glycine dehydrogenase (cytochrome) D 1.4.2.- C 1.4.3 With oxygen as acceptor D 1.4.3.1 D-aspartate oxidase D 1.4.3.2 L-amino-acid oxidase D 1.4.3.3 D-amino-acid oxidase D 1.4.3.4 monoamine oxidase D 1.4.3.5 pyridoxal 5'-phosphate synthase D 1.4.3.7 D-glutamate oxidase D 1.4.3.8 ethanolamine oxidase D 1.4.3.10 putrescine oxidase D 1.4.3.11 L-glutamate oxidase D 1.4.3.12 cyclohexylamine oxidase D 1.4.3.13 protein-lysine 6-oxidase D 1.4.3.14 L-lysine oxidase D 1.4.3.15 D-glutamate(D-aspartate) oxidase D 1.4.3.16 L-aspartate oxidase E PRU_1996 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D 1.4.3.19 glycine oxidase D 1.4.3.20 L-lysine 6-oxidase D 1.4.3.21 primary-amine oxidase D 1.4.3.22 diamine oxidase D 1.4.3.23 7-chloro-L-tryptophan oxidase D 1.4.3.24 pseudooxynicotine oxidase D 1.4.3.- C 1.4.4 With a disulfide as acceptor D 1.4.4.2 glycine dehydrogenase (decarboxylating) E PRU_2046 gcvP1; glycine dehydrogenase subunit 1 K00282 gcvPA; glycine dehydrogenase subunit 1 [EC:1.4.4.2] E PRU_2045 gcvP2; glycine dehydrogenase subunit 2 K00283 gcvPB; glycine dehydrogenase subunit 2 [EC:1.4.4.2] C 1.4.5 With a quinone or other compound as acceptor D 1.4.5.1 D-amino acid dehydrogenase (quinone) C 1.4.7 With an iron-sulfur protein as acceptor D 1.4.7.1 glutamate synthase (ferredoxin) C 1.4.9 With a copper protein as acceptor D 1.4.9.1 methylamine dehydrogenase (amicyanin) D 1.4.9.2 aralkylamine dehydrogenase (azurin) C 1.4.99 With other acceptors D 1.4.99.1 D-amino-acid dehydrogenase D 1.4.99.2 taurine dehydrogenase D 1.4.99.5 glycine dehydrogenase (cyanide-forming) D 1.4.99.- C 1.4.- Acting on the CH-NH2 group of donors D 1.4.-.- B 1.5 Acting on the CH-NH group of donors C 1.5.1 With NAD+ or NADP+ as acceptor D 1.5.1.1 pyrroline-2-carboxylate reductase D 1.5.1.2 pyrroline-5-carboxylate reductase E PRU_2202 proC; pyrroline-5-carboxylate reductase K00286 E1.5.1.2; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D 1.5.1.3 dihydrofolate reductase E PRU_1279 folA; dihydrofolate reductase K00287 folA; dihydrofolate reductase [EC:1.5.1.3] D 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+) E PRU_1152 folD; bifunctional protein FolD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D 1.5.1.6 formyltetrahydrofolate dehydrogenase D 1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming) E PRU_0067 lys1; saccharopine dehydrogenase K00290 LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7] D 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming) D 1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming) D 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming) D 1.5.1.11 D-octopine dehydrogenase D 1.5.1.12 1-pyrroline-5-carboxylate dehydrogenase D 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) D 1.5.1.16 D-lysopine dehydrogenase D 1.5.1.17 alanopine dehydrogenase D 1.5.1.18 ephedrine dehydrogenase D 1.5.1.19 D-nopaline dehydrogenase D 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H] E PRU_1700 metF; methylenetetrahydrofolate reductase (NAD(P)H) K00297 metF; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] D 1.5.1.21 Delta1-piperideine-2-carboxylate reductase D 1.5.1.22 strombine dehydrogenase D 1.5.1.23 tauropine dehydrogenase D 1.5.1.24 N5-(carboxyethyl)ornithine synthase D 1.5.1.25 thiomorpholine-carboxylate dehydrogenase D 1.5.1.26 beta-alanopine dehydrogenase D 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH) D 1.5.1.28 opine dehydrogenase D 1.5.1.30 flavin reductase (NADPH) D 1.5.1.31 berberine reductase D 1.5.1.32 vomilenine reductase D 1.5.1.33 pteridine reductase D 1.5.1.34 6,7-dihydropteridine reductase D 1.5.1.36 flavin reductase (NADH) D 1.5.1.37 FAD reductase (NADH) D 1.5.1.38 FMN reductase (NADPH) D 1.5.1.39 FMN reductase [NAD(P)H] D 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase D 1.5.1.41 riboflavin reductase [NAD(P)H] D 1.5.1.42 FMN reductase (NADH) D 1.5.1.43 carboxynorspermidine synthase D 1.5.1.44 festuclavine dehydrogenase D 1.5.1.45 FAD reductase [NAD(P)H] D 1.5.1.46 agroclavine dehydrogenase D 1.5.1.- C 1.5.3 With oxygen as acceptor D 1.5.3.1 sarcosine oxidase D 1.5.3.2 N-methyl-L-amino-acid oxidase D 1.5.3.4 N6-methyl-lysine oxidase D 1.5.3.5 (S)-6-hydroxynicotine oxidase D 1.5.3.6 (R)-6-hydroxynicotine oxidase D 1.5.3.7 L-pipecolate oxidase D 1.5.3.10 dimethylglycine oxidase D 1.5.3.12 dihydrobenzophenanthridine oxidase D 1.5.3.13 N1-acetylpolyamine oxidase D 1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming) D 1.5.3.15 N8-acetylspermidine oxidase (propane-1,3-diamine-forming) D 1.5.3.16 spermine oxidase D 1.5.3.17 non-specific polyamine oxidase D 1.5.3.18 L-saccharopine oxidase D 1.5.3.19 4-methylaminobutanoate oxidase (formaldehyde-forming) D 1.5.3.20 N-alkylglycine oxidase D 1.5.3.21 4-methylaminobutanoate oxidase (methylamine-forming) D 1.5.3.- C 1.5.4 With a disulfide as acceptor D 1.5.4.1 pyrimidodiazepine synthase C 1.5.5 With a quinone or similar compound as acceptor D 1.5.5.1 electron-transferring-flavoprotein dehydrogenase D 1.5.5.- C 1.5.7 With an iron-sulfur protein as acceptor D 1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin) C 1.5.8 With a flavin or flavoprotein as acceptor D 1.5.8.1 dimethylamine dehydrogenase D 1.5.8.2 trimethylamine dehydrogenase D 1.5.8.3 sarcosine dehydrogenase D 1.5.8.4 dimethylglycine dehydrogenase C 1.5.99 With other acceptors D 1.5.99.3 L-pipecolate dehydrogenase D 1.5.99.4 nicotine dehydrogenase D 1.5.99.5 methylglutamate dehydrogenase D 1.5.99.6 spermidine dehydrogenase D 1.5.99.8 proline dehydrogenase D 1.5.99.9 methylenetetrahydromethanopterin dehydrogenase D 1.5.99.11 5,10-methylenetetrahydromethanopterin reductase D 1.5.99.12 cytokinin dehydrogenase D 1.5.99.13 D-proline dehydrogenase D 1.5.99.14 6-hydroxypseudooxynicotine dehydrogenase D 1.5.99.- C 1.5.- Acting on the CH-NH group of donors D 1.5.-.- B 1.6 Acting on NADH or NADPH C 1.6.1 With NAD+ or NADP+ as acceptor D 1.6.1.1 NAD(P)+ transhydrogenase (B-specific) D 1.6.1.2 NAD(P)+ transhydrogenase (AB-specific) C 1.6.2 With a heme protein as acceptor D 1.6.2.2 cytochrome-b5 reductase D 1.6.2.4 NADPH---hemoprotein reductase D 1.6.2.5 NADPH---cytochrome-c2 reductase D 1.6.2.6 leghemoglobin reductase C 1.6.3 With oxygen as acceptor D 1.6.3.1 NAD(P)H oxidase D 1.6.3.- C 1.6.4 With a disulfide as acceptor D 1.6.4.- C 1.6.5 With a quinone or similar compound as acceptor D 1.6.5.2 NAD(P)H dehydrogenase (quinone) D 1.6.5.3 NADH:ubiquinone reductase (H+-translocating) E PRU_1721 proton-translocating NADH-quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:1.6.5.3] E PRU_1718 proton-translocating NADH-quinone oxidoreductase H subunit K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:1.6.5.3] E PRU_1717 proton-translocating NADH-quinone oxidoreductase I subunit K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:1.6.5.3] E PRU_1716 proton-translocating NADH-quinone oxidoreductase J subunit K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:1.6.5.3] E PRU_1715 proton-translocating NADH-quinone oxidoreductase K subunit K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:1.6.5.3] E PRU_1714 proton-translocating NADH-quinone oxidoreductase L subunit K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:1.6.5.3] E PRU_1713 proton-translocating NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:1.6.5.3] E PRU_1712 proton-translocating NADH-quinone oxidoreductase N subunit K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:1.6.5.3] E PRU_1719 proton-translocating NADH-quinone oxidoreductase D subunit K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:1.6.5.3] D 1.6.5.4 monodehydroascorbate reductase (NADH) D 1.6.5.5 NADPH:quinone reductase D 1.6.5.6 p-benzoquinone reductase (NADPH) D 1.6.5.7 2-hydroxy-1,4-benzoquinone reductase D 1.6.5.8 NADH:ubiquinone reductase (Na+-transporting) D 1.6.5.9 NADH:ubiquinone reductase (non-electrogenic) D 1.6.5.10 NADPH dehydrogenase (quinone) D 1.6.5.- E PRU_1250 nqrA; NADH:ubiquinone oxidoreductase Na(+)-translocating subunit A K00346 nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:1.6.5.-] E PRU_1249 nqrB; NADH:ubiquinone oxidoreductase subunit B K00347 nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:1.6.5.-] E PRU_1248 nqrC; NADH:ubiquinone oxidoreductase Na(+)-translocating subunit C K00348 nqrC; Na+-transporting NADH:ubiquinone oxidoreductase subunit C [EC:1.6.5.-] E PRU_1247 nqrD; NADH:ubiquinone oxidoreductase D subunit K00349 nqrD; Na+-transporting NADH:ubiquinone oxidoreductase subunit D [EC:1.6.5.-] E PRU_1246 nqrE; NADH:ubiquinone oxidoreductase E subunit K00350 nqrE; Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC:1.6.5.-] E PRU_1245 nqrF; NADH:ubiquinone oxidoreductase F subunit K00351 nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:1.6.5.-] C 1.6.6 With a nitrogenous group as acceptor D 1.6.6.9 trimethylamine-N-oxide reductase D 1.6.6.- C 1.6.99 With other acceptors D 1.6.99.1 NADPH dehydrogenase D 1.6.99.3 NADH dehydrogenase D 1.6.99.5 NADH dehydrogenase (quinone) D 1.6.99.- C 1.6.- Acting on NADH or NADPH D 1.6.-.- B 1.7 Acting on other nitrogenous compounds as donors C 1.7.1 With NAD+ or NADP+ as acceptor D 1.7.1.1 nitrate reductase (NADH) D 1.7.1.2 nitrate reductase [NAD(P)H] D 1.7.1.3 nitrate reductase (NADPH) D 1.7.1.4 nitrite reductase [NAD(P)H] D 1.7.1.5 hyponitrite reductase D 1.7.1.6 azobenzene reductase D 1.7.1.7 GMP reductase D 1.7.1.9 nitroquinoline-N-oxide reductase D 1.7.1.10 hydroxylamine reductase (NADH) D 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase D 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase D 1.7.1.13 preQ1 synthase E PRU_0253 GTP cyclohydrolase family protein K09457 K09457; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming] D 1.7.1.- C 1.7.2 With a cytochrome as acceptor D 1.7.2.1 nitrite reductase (NO-forming) D 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming) D 1.7.2.3 trimethylamine-N-oxide reductase (cytochrome c) D 1.7.2.4 nitrous-oxide reductase D 1.7.2.5 nitric oxide reductase (cytochrome c) D 1.7.2.6 hydroxylamine dehydrogenase C 1.7.3 With oxygen as acceptor D 1.7.3.1 nitroalkane oxidase D 1.7.3.2 acetylindoxyl oxidase D 1.7.3.3 factor-independent urate hydroxylase D 1.7.3.5 3-aci-nitropropanoate oxidase D 1.7.3.6 hydroxylamine oxidase (cytochrome) D 1.7.3.- C 1.7.5 With a quinone or similar compound as acceptor D 1.7.5.1 nitrate reductase (quinone) D 1.7.5.2 nitric oxide reductase (menaquinol) C 1.7.6 With a nitrogenous group as acceptor D 1.7.6.1 nitrite dismutase C 1.7.7 With an iron-sulfur protein as acceptor D 1.7.7.1 ferredoxin---nitrite reductase D 1.7.7.2 ferredoxin---nitrate reductase C 1.7.99 With other acceptors D 1.7.99.1 hydroxylamine reductase D 1.7.99.4 nitrate reductase D 1.7.99.8 hydrazine oxidoreductase C 1.7.- Acting on other nitrogenous compounds as donors D 1.7.-.- B 1.8 Acting on a sulfur group of donors C 1.8.1 With NAD+ or NADP+ as acceptor D 1.8.1.2 sulfite reductase (NADPH) D 1.8.1.3 hypotaurine dehydrogenase D 1.8.1.4 dihydrolipoyl dehydrogenase E PRU_2044 dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoamide dehydrogenase [EC:1.8.1.4] D 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating) D 1.8.1.6 cystine reductase D 1.8.1.7 glutathione-disulfide reductase D 1.8.1.8 protein-disulfide reductase D 1.8.1.9 thioredoxin-disulfide reductase E PRU_1348 trxB; thioredoxin-disulfide reductase K00384 E1.8.1.9; thioredoxin reductase (NADPH) [EC:1.8.1.9] D 1.8.1.10 CoA-glutathione reductase D 1.8.1.11 asparagusate reductase D 1.8.1.12 trypanothione-disulfide reductase D 1.8.1.13 bis-gamma-glutamylcystine reductase D 1.8.1.14 CoA-disulfide reductase D 1.8.1.15 mycothione reductase D 1.8.1.16 glutathione amide reductase D 1.8.1.17 dimethylsulfone reductase D 1.8.1.- C 1.8.2 With a cytochrome as acceptor D 1.8.2.1 sulfite dehydrogenase D 1.8.2.2 thiosulfate dehydrogenase D 1.8.2.3 sulfide-cytochrome-c reductase (flavocytochrome c) D 1.8.2.4 dimethyl sulfide:cytochrome c2 reductase D 1.8.2.- C 1.8.3 With oxygen as acceptor D 1.8.3.1 sulfite oxidase D 1.8.3.2 thiol oxidase D 1.8.3.3 glutathione oxidase D 1.8.3.4 methanethiol oxidase D 1.8.3.5 prenylcysteine oxidase D 1.8.3.6 farnesylcysteine lyase C 1.8.4 With a disulfide as acceptor D 1.8.4.1 glutathione---homocystine transhydrogenase D 1.8.4.2 protein-disulfide reductase (glutathione) D 1.8.4.3 glutathione---CoA-glutathione transhydrogenase D 1.8.4.4 glutathione---cystine transhydrogenase D 1.8.4.7 enzyme-thiol transhydrogenase (glutathione-disulfide) D 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin) D 1.8.4.9 adenylyl-sulfate reductase (glutathione) D 1.8.4.10 adenylyl-sulfate reductase (thioredoxin) D 1.8.4.11 peptide-methionine (S)-S-oxide reductase E PRU_0466 msrA; methionine-S-sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D 1.8.4.12 peptide-methionine (R)-S-oxide reductase E PRU_0466 msrA; methionine-S-sulfoxide reductase K12267 msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12] D 1.8.4.13 L-methionine (S)-S-oxide reductase D 1.8.4.14 L-methionine (R)-S-oxide reductase D 1.8.4.- C 1.8.5 With a quinone or similar compound as acceptor D 1.8.5.1 glutathione dehydrogenase (ascorbate) D 1.8.5.2 thiosulfate dehydrogenase (quinone) D 1.8.5.3 dimethylsulfoxide reductase D 1.8.5.4 sulfide:quinone reductase D 1.8.5.- C 1.8.7 With an iron-sulfur protein as acceptor D 1.8.7.1 sulfite reductase (ferredoxin) D 1.8.7.2 ferredoxin:thioredoxin reductase C 1.8.98 With other, known, acceptors D 1.8.98.1 CoB---CoM heterodisulfide reductase D 1.8.98.2 sulfiredoxin C 1.8.99 With other acceptors D 1.8.99.1 sulfite reductase D 1.8.99.2 adenylyl-sulfate reductase D 1.8.99.3 hydrogensulfite reductase D 1.8.99.- C 1.8.- Acting on a sulfur group of donors D 1.8.-.- B 1.9 Acting on a heme group of donors C 1.9.3 With oxygen as acceptor D 1.9.3.1 cytochrome-c oxidase C 1.9.6 With a nitrogenous group as acceptor D 1.9.6.1 nitrate reductase (cytochrome) C 1.9.99 With other acceptors D 1.9.99.1 iron---cytochrome-c reductase B 1.10 Acting on diphenols and related substances as donors C 1.10.1 With NAD+ or NADP+ as acceptor D 1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase C 1.10.2 With a cytochrome as acceptor D 1.10.2.1 L-ascorbate---cytochrome-b5 reductase D 1.10.2.2 ubiquinol---cytochrome-c reductase D 1.10.2.- C 1.10.3 With oxygen as acceptor D 1.10.3.1 catechol oxidase D 1.10.3.2 laccase D 1.10.3.3 L-ascorbate oxidase D 1.10.3.4 o-aminophenol oxidase D 1.10.3.5 3-hydroxyanthranilate oxidase D 1.10.3.6 rifamycin-B oxidase D 1.10.3.9 photosystem II D 1.10.3.10 ubiquinol oxidase (H+-transporting) D 1.10.3.11 ubiquinol oxidase D 1.10.3.12 menaquinol oxidase (H+-transporting) D 1.10.3.- E PRU_1261 cytochrome d ubiquinol oxidase K00425 cydA; cytochrome d ubiquinol oxidase subunit I [EC:1.10.3.-] E PRU_1262 cydB; cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome d ubiquinol oxidase subunit II [EC:1.10.3.-] C 1.10.9 With a copper protein as acceptor D 1.10.9.1 plastoquinol---plastocyanin reductase C 1.10.99 With other acceptors D 1.10.99.2 ribosyldihydronicotinamide dehydrogenase (quinone) D 1.10.99.3 violaxanthin de-epoxidase B 1.11 Acting on a peroxide as acceptor C 1.11.1 Peroxidases D 1.11.1.1 NADH peroxidase D 1.11.1.2 NADPH peroxidase D 1.11.1.3 fatty-acid peroxidase D 1.11.1.5 cytochrome-c peroxidase D 1.11.1.6 catalase D 1.11.1.7 peroxidase D 1.11.1.8 iodide peroxidase D 1.11.1.9 glutathione peroxidase E PRU_1347 glutathione peroxidase K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9] E PRU_2788 glutathione peroxidase family protein K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9] D 1.11.1.10 chloride peroxidase D 1.11.1.11 L-ascorbate peroxidase D 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase D 1.11.1.13 manganese peroxidase D 1.11.1.14 lignin peroxidase D 1.11.1.15 peroxiredoxin E PRU_2409 bcp; thioredoxin-dependent thiol peroxidase Bcp K03564 BCP; peroxiredoxin Q/BCP [EC:1.11.1.15] D 1.11.1.16 versatile peroxidase D 1.11.1.17 glutathione amide-dependent peroxidase D 1.11.1.18 bromide peroxidase D 1.11.1.19 dye decolorizing peroxidase D 1.11.1.20 prostamide/prostaglandin F2alpha synthase D 1.11.1.21 catalase-peroxidase D 1.11.1.22 hydroperoxy fatty acid reductase D 1.11.1.- C 1.11.2 Peroxygenases D 1.11.2.1 unspecific peroxygenase D 1.11.2.2 myeloperoxidase D 1.11.2.3 plant seed peroxygenase D 1.11.2.4 fatty-acid peroxygenase B 1.12 Acting on hydrogen as donor C 1.12.1 With NAD+ or NADP+ as acceptor D 1.12.1.2 hydrogen dehydrogenase D 1.12.1.3 hydrogen dehydrogenase (NADP+) D 1.12.1.4 hydrogenase (NAD+, ferredoxin) D 1.12.1.5 hydrogen dehydrogenase [NAD(P)+] C 1.12.2 With a cytochrome as acceptor D 1.12.2.1 cytochrome-c3 hydrogenase D 1.12.2.- C 1.12.5 With a quinone or similar compound as acceptor D 1.12.5.1 hydrogen:quinone oxidoreductase C 1.12.7 With an iron-sulfur protein as acceptor D 1.12.7.2 ferredoxin hydrogenase C 1.12.98 With other, known, acceptors D 1.12.98.1 coenzyme F420 hydrogenase D 1.12.98.2 5,10-methenyltetrahydromethanopterin hydrogenase D 1.12.98.3 Methanosarcina-phenazine hydrogenase D 1.12.98.4 sulfhydrogenase C 1.12.99 With other acceptors D 1.12.99.6 hydrogenase (acceptor) D 1.12.99.- C 1.12.- Acting on hydrogen as donor D 1.12.-.- B 1.13 Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2 C 1.13.11 With incorporation of two atoms of oxygen D 1.13.11.1 catechol 1,2-dioxygenase D 1.13.11.2 catechol 2,3-dioxygenase D 1.13.11.3 protocatechuate 3,4-dioxygenase D 1.13.11.4 gentisate 1,2-dioxygenase D 1.13.11.5 homogentisate 1,2-dioxygenase D 1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase D 1.13.11.8 protocatechuate 4,5-dioxygenase D 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase D 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase D 1.13.11.11 tryptophan 2,3-dioxygenase D 1.13.11.12 linoleate 13S-lipoxygenase D 1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase D 1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase D 1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase D 1.13.11.17 indole 2,3-dioxygenase D 1.13.11.18 sulfur dioxygenase D 1.13.11.19 cysteamine dioxygenase D 1.13.11.20 cysteine dioxygenase D 1.13.11.22 caffeate 3,4-dioxygenase D 1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase D 1.13.11.24 quercetin 2,3-dioxygenase D 1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase D 1.13.11.26 peptide-tryptophan 2,3-dioxygenase D 1.13.11.27 4-hydroxyphenylpyruvate dioxygenase D 1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase D 1.13.11.29 stizolobate synthase D 1.13.11.30 stizolobinate synthase D 1.13.11.31 arachidonate 12-lipoxygenase D 1.13.11.33 arachidonate 15-lipoxygenase D 1.13.11.34 arachidonate 5-lipoxygenase D 1.13.11.35 pyrogallol 1,2-oxygenase D 1.13.11.36 chloridazon-catechol dioxygenase D 1.13.11.37 hydroxyquinol 1,2-dioxygenase D 1.13.11.38 1-hydroxy-2-naphthoate 1,2-dioxygenase D 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase D 1.13.11.40 arachidonate 8-lipoxygenase D 1.13.11.41 2,4'-dihydroxyacetophenone dioxygenase D 1.13.11.43 lignostilbene alphabeta-dioxygenase D 1.13.11.45 linoleate 11-lipoxygenase D 1.13.11.46 4-hydroxymandelate synthase D 1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase D 1.13.11.48 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase D 1.13.11.49 chlorite O2-lyase D 1.13.11.50 acetylacetone-cleaving enzyme D 1.13.11.51 9-cis-epoxycarotenoid dioxygenase D 1.13.11.52 indoleamine 2,3-dioxygenase D 1.13.11.53 acireductone dioxygenase (Ni2+-requiring) D 1.13.11.54 acireductone dioxygenase [iron(II)-requiring] D 1.13.11.55 sulfur oxygenase/reductase D 1.13.11.56 1,2-dihydroxynaphthalene dioxygenase D 1.13.11.57 gallate dioxygenase D 1.13.11.58 linoleate 9S-lipoxygenase D 1.13.11.59 torulene dioxygenase D 1.13.11.60 linoleate 8R-lipoxygenase D 1.13.11.61 linolenate 9R-lipoxygenase D 1.13.11.62 linoleate 10R-lipoxygenase D 1.13.11.63 beta-carotene 15,15'-dioxygenase D 1.13.11.64 5-nitrosalicylate dioxygenase D 1.13.11.65 carotenoid isomerooxygenase D 1.13.11.66 hydroquinone 1,2-dioxygenase D 1.13.11.67 8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase D 1.13.11.68 9-cis-beta-carotene 9',10'-cleaving dioxygenase D 1.13.11.69 carlactone synthase D 1.13.11.70 all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase D 1.13.11.71 carotenoid-9',10'-cleaving dioxygenase D 1.13.11.72 2-hydroxyethylphosphonate dioxygenase D 1.13.11.73 methylphosphonate synthase D 1.13.11.- C 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) D 1.13.12.1 arginine 2-monooxygenase D 1.13.12.2 lysine 2-monooxygenase D 1.13.12.3 tryptophan 2-monooxygenase D 1.13.12.4 lactate 2-monooxygenase D 1.13.12.5 Renilla-luciferin 2-monooxygenase D 1.13.12.6 Cypridina-luciferin 2-monooxygenase D 1.13.12.7 Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) D 1.13.12.8 Watasenia-luciferin 2-monooxygenase D 1.13.12.9 phenylalanine 2-monooxygenase D 1.13.12.13 Oplophorus-luciferin 2-monooxygenase D 1.13.12.15 3,4-dihydroxyphenylalanine oxidative deaminase D 1.13.12.16 nitronate monooxygenase D 1.13.12.17 dichloroarcyriaflavin A synthase D 1.13.12.18 dinoflagellate luciferase D 1.13.12.19 2-oxoglutarate dioxygenase (ethylene-forming) D 1.13.12.20 noranthrone monooxygenase D 1.13.12.- C 1.13.99 Miscellaneous D 1.13.99.1 inositol oxygenase D 1.13.99.3 tryptophan 2'-dioxygenase C 1.13.- Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2 D 1.13.-.- B 1.14 Acting on paired donors with incorporation of molecular oxygen C 1.14.1 D 1.14.1.- C 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor D 1.14.11.1 gamma-butyrobetaine dioxygenase D 1.14.11.2 procollagen-proline dioxygenase D 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase D 1.14.11.4 procollagen-lysine 5-dioxygenase D 1.14.11.6 thymine dioxygenase D 1.14.11.7 procollagen-proline 3-dioxygenase D 1.14.11.8 trimethyllysine dioxygenase D 1.14.11.9 flavanone 3-dioxygenase D 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase D 1.14.11.11 hyoscyamine (6S)-dioxygenase D 1.14.11.12 gibberellin-44 dioxygenase D 1.14.11.13 gibberellin 2beta-dioxygenase D 1.14.11.14 6beta-hydroxyhyoscyamine epoxidase D 1.14.11.15 gibberellin 3beta-dioxygenase D 1.14.11.16 peptide-aspartate beta-dioxygenase D 1.14.11.17 taurine dioxygenase D 1.14.11.18 phytanoyl-CoA dioxygenase D 1.14.11.19 leucocyanidin oxygenase D 1.14.11.20 deacetoxyvindoline 4-hydroxylase D 1.14.11.21 clavaminate synthase D 1.14.11.22 flavone synthase D 1.14.11.23 flavonol synthase D 1.14.11.24 2'-deoxymugineic-acid 2'-dioxygenase D 1.14.11.25 mugineic-acid 3-dioxygenase D 1.14.11.26 deacetoxycephalosporin-C hydroxylase D 1.14.11.27 [histone-H3]-lysine-36 demethylase D 1.14.11.28 proline 3-hydroxylase D 1.14.11.29 hypoxia-inducible factor-proline dioxygenase D 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase D 1.14.11.31 thebaine 6-O-demethylase D 1.14.11.32 codeine 3-O-demethylase D 1.14.11.33 DNA oxidative demethylase D 1.14.11.34 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) D 1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase D 1.14.11.36 pentalenolactone F synthase D 1.14.11.- C 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor D 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) D 1.14.12.3 benzene 1,2-dioxygenase D 1.14.12.4 3-hydroxy-2-methylpyridinecarboxylate dioxygenase D 1.14.12.5 5-pyridoxate dioxygenase D 1.14.12.7 phthalate 4,5-dioxygenase D 1.14.12.8 4-sulfobenzoate 3,4-dioxygenase D 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase D 1.14.12.10 benzoate 1,2-dioxygenase D 1.14.12.11 toluene dioxygenase D 1.14.12.12 naphthalene 1,2-dioxygenase D 1.14.12.13 2-halobenzoate 1,2-dioxygenase D 1.14.12.14 2-aminobenzenesulfonate 2,3-dioxygenase D 1.14.12.15 terephthalate 1,2-dioxygenase D 1.14.12.16 2-hydroxyquinoline 5,6-dioxygenase D 1.14.12.17 nitric oxide dioxygenase D 1.14.12.18 biphenyl 2,3-dioxygenase D 1.14.12.19 3-phenylpropanoate dioxygenase D 1.14.12.20 pheophorbide a oxygenase D 1.14.12.21 benzoyl-CoA 2,3-dioxygenase D 1.14.12.22 carbazole 1,9a-dioxygenase D 1.14.12.- C 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.13.1 salicylate 1-monooxygenase D 1.14.13.2 4-hydroxybenzoate 3-monooxygenase D 1.14.13.4 melilotate 3-monooxygenase D 1.14.13.5 imidazoleacetate 4-monooxygenase D 1.14.13.6 orcinol 2-monooxygenase D 1.14.13.7 phenol 2-monooxygenase D 1.14.13.8 flavin-containing monooxygenase D 1.14.13.9 kynurenine 3-monooxygenase D 1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase D 1.14.13.11 trans-cinnamate 4-monooxygenase D 1.14.13.12 benzoate 4-monooxygenase D 1.14.13.13 calcidiol 1-monooxygenase D 1.14.13.14 trans-cinnamate 2-monooxygenase D 1.14.13.15 cholestanetriol 26-monooxygenase D 1.14.13.16 cyclopentanone monooxygenase D 1.14.13.17 cholesterol 7alpha-monooxygenase D 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase D 1.14.13.19 taxifolin 8-monooxygenase D 1.14.13.20 2,4-dichlorophenol 6-monooxygenase D 1.14.13.21 flavonoid 3'-monooxygenase D 1.14.13.22 cyclohexanone monooxygenase D 1.14.13.23 3-hydroxybenzoate 4-monooxygenase D 1.14.13.24 3-hydroxybenzoate 6-monooxygenase D 1.14.13.25 methane monooxygenase (soluble) D 1.14.13.26 phosphatidylcholine 12-monooxygenase D 1.14.13.27 4-aminobenzoate 1-monooxygenase D 1.14.13.28 3,9-dihydroxypterocarpan 6a-monooxygenase D 1.14.13.29 4-nitrophenol 2-monooxygenase D 1.14.13.30 leukotriene-B4 20-monooxygenase D 1.14.13.31 2-nitrophenol 2-monooxygenase D 1.14.13.32 albendazole monooxygenase D 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] D 1.14.13.34 leukotriene-E4 20-monooxygenase D 1.14.13.35 anthranilate 3-monooxygenase (deaminating) D 1.14.13.36 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase D 1.14.13.37 methyltetrahydroprotoberberine 14-monooxygenase D 1.14.13.38 anhydrotetracycline monooxygenase D 1.14.13.39 nitric-oxide synthase (NADPH dependent) D 1.14.13.40 anthraniloyl-CoA monooxygenase D 1.14.13.41 tyrosine N-monooxygenase D 1.14.13.43 questin monooxygenase D 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase D 1.14.13.46 (-)-menthol monooxygenase D 1.14.13.47 (S)-limonene 3-monooxygenase D 1.14.13.48 (S)-limonene 6-monooxygenase D 1.14.13.49 (S)-limonene 7-monooxygenase D 1.14.13.50 pentachlorophenol monooxygenase D 1.14.13.51 6-oxocineole dehydrogenase D 1.14.13.52 isoflavone 3'-hydroxylase D 1.14.13.53 4'-methoxyisoflavone 2'-hydroxylase D 1.14.13.54 ketosteroid monooxygenase D 1.14.13.55 protopine 6-monooxygenase D 1.14.13.56 dihydrosanguinarine 10-monooxygenase D 1.14.13.57 dihydrochelirubine 12-monooxygenase D 1.14.13.58 benzoyl-CoA 3-monooxygenase D 1.14.13.59 L-lysine N6-monooxygenase (NADPH) D 1.14.13.60 27-hydroxycholesterol 7alpha-monooxygenase D 1.14.13.61 2-hydroxyquinoline 8-monooxygenase D 1.14.13.62 4-hydroxyquinoline 3-monooxygenase D 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase D 1.14.13.64 4-hydroxybenzoate 1-hydroxylase D 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase D 1.14.13.67 quinine 3-monooxygenase D 1.14.13.68 4-hydroxyphenylacetaldehyde oxime monooxygenase D 1.14.13.69 alkene monooxygenase D 1.14.13.70 sterol 14alpha-demethylase D 1.14.13.71 N-methylcoclaurine 3'-monooxygenase D 1.14.13.72 methylsterol monooxygenase D 1.14.13.73 tabersonine 16-hydroxylase D 1.14.13.74 7-deoxyloganin 7-hydroxylase D 1.14.13.75 vinorine hydroxylase D 1.14.13.76 taxane 10beta-hydroxylase D 1.14.13.77 taxane 13alpha-hydroxylase D 1.14.13.78 ent-kaurene oxidase D 1.14.13.79 ent-kaurenoic acid oxidase D 1.14.13.80 (R)-limonene 6-monooxygenase D 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase D 1.14.13.82 vanillate monooxygenase D 1.14.13.83 precorrin-3B synthase D 1.14.13.84 4-hydroxyacetophenone monooxygenase D 1.14.13.85 glyceollin synthase D 1.14.13.86 2-hydroxyisoflavanone synthase D 1.14.13.87 licodione synthase D 1.14.13.88 flavanoid 3',5'-hydroxylase D 1.14.13.89 isoflavone 2'-hydroxylase D 1.14.13.90 zeaxanthin epoxidase D 1.14.13.91 deoxysarpagine hydroxylase D 1.14.13.92 phenylacetone monooxygenase D 1.14.13.93 (+)-abscisic acid 8'-hydroxylase D 1.14.13.94 lithocholate 6beta-hydroxylase D 1.14.13.95 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase D 1.14.13.96 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase D 1.14.13.97 taurochenodeoxycholate 6alpha-hydroxylase D 1.14.13.98 cholesterol 24-hydroxylase D 1.14.13.99 24-hydroxycholesterol 7alpha-hydroxylase D 1.14.13.100 25-hydroxycholesterol 7alpha-hydroxylase D 1.14.13.101 senecionine N-oxygenase D 1.14.13.102 psoralen synthase D 1.14.13.103 8-dimethylallylnaringenin 2'-hydroxylase D 1.14.13.104 (+)-menthofuran synthase D 1.14.13.105 monocyclic monoterpene ketone monooxygenase D 1.14.13.106 epi-isozizaene 5-monooxygenase D 1.14.13.107 limonene 1,2-monooxygenase D 1.14.13.108 abieta-7,13-diene hydroxylase D 1.14.13.109 abieta-7,13-dien-18-ol hydroxylase D 1.14.13.110 geranylgeraniol 18-hydroxylase D 1.14.13.111 methanesulfonate monooxygenase D 1.14.13.112 3-epi-6-deoxocathasterone 23-monooxygenase D 1.14.13.113 FAD-dependent urate hydroxylase D 1.14.13.114 6-hydroxynicotinate 3-monooxygenase D 1.14.13.115 angelicin synthase D 1.14.13.116 geranylhydroquinone 3''-hydroxylase D 1.14.13.117 isoleucine N-monooxygenase D 1.14.13.118 valine N-monooxygenase D 1.14.13.119 5-epiaristolochene 1,3-dihydroxylase D 1.14.13.120 costunolide synthase D 1.14.13.121 premnaspirodiene oxygenase D 1.14.13.122 chlorophyllide-a oxygenase D 1.14.13.123 germacrene A hydroxylase D 1.14.13.124 phenylalanine N-monooxygenase D 1.14.13.125 tryptophan N-monooxygenase D 1.14.13.126 vitamin D3 24-hydroxylase D 1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase D 1.14.13.128 7-methylxanthine demethylase D 1.14.13.129 beta-carotene 3-hydroxylase D 1.14.13.130 pyrrole-2-carboxylate monooxygenase D 1.14.13.131 dimethyl-sulfide monooxygenase D 1.14.13.132 squalene monooxygenase D 1.14.13.133 pentalenene oxygenase D 1.14.13.134 beta-amyrin 11-oxidase D 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase D 1.14.13.136 isoflavonoid synthase D 1.14.13.137 indole-2-monooxygenase D 1.14.13.138 indolin-2-one monooxygenase D 1.14.13.139 3-hydroxyindolin-2-one monooxygenase D 1.14.13.140 2-hydroxy-1,4-benzoxazin-3-one monooxygenase D 1.14.13.141 cholest-4-en-3-one 26-monooxygenase D 1.14.13.142 3-ketosteroid 9alpha-monooxygenase D 1.14.13.143 ent-isokaurene C2-hydroxylase D 1.14.13.144 9beta-pimara-7,15-diene oxidase D 1.14.13.145 ent-cassa-12,15-diene 11-hydroxylase D 1.14.13.146 taxoid 14beta-hydroxylase D 1.14.13.147 taxoid 7beta-hydroxylase D 1.14.13.148 trimethylamine monooxygenase D 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase D 1.14.13.150 alpha-humulene 10-hydroxylase D 1.14.13.151 linalool 8-monooxygenase D 1.14.13.152 geraniol 8-hydroxylase D 1.14.13.153 (+)-sabinene 3-hydroxylase D 1.14.13.154 erythromycin 12 hydroxylase D 1.14.13.155 alpha-pinene monooxygenase D 1.14.13.156 1,8-cineole 2-endo-monooxygenase D 1.14.13.157 1,8-cineole 2-exo-monooxygenase D 1.14.13.158 amorpha-4,11-diene 12-monooxygenase D 1.14.13.159 vitamin D 25-hydroxylase D 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase D 1.14.13.161 (+)-camphor 6-exo-hydroxylase D 1.14.13.162 2,5-diketocamphane 1,2-monooxygenase D 1.14.13.163 6-hydroxy-3-succinoylpyridine 3-monooxygenase D 1.14.13.165 nitric-oxide synthase [NAD(P)H-dependent] D 1.14.13.166 4-nitrocatechol 4-monooxygenase D 1.14.13.167 4-nitrophenol 4-monooxygenase D 1.14.13.168 indole-3-pyruvate monooxygenase D 1.14.13.169 sphinganine C4-monooxygenase D 1.14.13.170 pentalenolactone D synthase D 1.14.13.171 neopentalenolactone D synthase D 1.14.13.- C 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.14.1 unspecific monooxygenase D 1.14.14.3 alkanal monooxygenase (FMN) D 1.14.14.5 alkanesulfonate monooxygenase D 1.14.14.7 tryptophan 7-halogenase D 1.14.14.8 anthranilate 3-monooxygenase (FAD) D 1.14.14.9 4-hydroxyphenylacetate 3-monooxygenase D 1.14.14.10 nitrilotriacetate monooxygenase D 1.14.14.11 styrene monooxygenase D 1.14.14.12 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase D 1.14.14.13 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase D 1.14.14.- C 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.15.1 camphor 5-monooxygenase D 1.14.15.3 alkane 1-monooxygenase D 1.14.15.4 steroid 11beta-monooxygenase D 1.14.15.5 corticosterone 18-monooxygenase D 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) D 1.14.15.7 choline monooxygenase D 1.14.15.8 steroid 15beta-monooxygenase D 1.14.15.9 spheroidene monooxygenase D 1.14.15.10 (+)-camphor 6-endo-hydroxylase D 1.14.15.11 pentalenic acid synthase D 1.14.15.12 pimeloyl-[acyl-carrier protein] synthase D 1.14.15.- C 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.16.1 phenylalanine 4-monooxygenase D 1.14.16.2 tyrosine 3-monooxygenase D 1.14.16.3 anthranilate 3-monooxygenase D 1.14.16.4 tryptophan 5-monooxygenase D 1.14.16.5 alkylglycerol monooxygenase D 1.14.16.6 mandelate 4-monooxygenase D 1.14.16.- C 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.17.1 dopamine beta-monooxygenase D 1.14.17.3 peptidylglycine monooxygenase D 1.14.17.4 aminocyclopropanecarboxylate oxidase C 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.18.1 tyrosinase D 1.14.18.2 CMP-N-acetylneuraminate monooxygenase D 1.14.18.3 methane monooxygenase (particulate) D 1.14.18.- C 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water D 1.14.19.1 stearoyl-CoA 9-desaturase D 1.14.19.2 acyl-[acyl-carrier-protein] desaturase D 1.14.19.3 linoleoyl-CoA desaturase D 1.14.19.4 Delta8-fatty-acid desaturase D 1.14.19.5 Delta11-fatty-acid desaturase D 1.14.19.6 Delta12-fatty-acid desaturase D 1.14.19.7 (S)-2-hydroxypropylphosphonic acid epoxidase D 1.14.19.- C 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated D 1.14.20.1 deacetoxycephalosporin-C synthase D 1.14.20.2 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase C 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated D 1.14.21.1 (S)-stylopine synthase D 1.14.21.2 (S)-cheilanthifoline synthase D 1.14.21.3 berbamunine synthase D 1.14.21.4 salutaridine synthase D 1.14.21.5 (S)-canadine synthase D 1.14.21.6 lathosterol oxidase D 1.14.21.7 biflaviolin synthase D 1.14.21.8 pseudobaptigenin synthase D 1.14.21.- C 1.14.99 Miscellaneous D 1.14.99.1 prostaglandin-endoperoxide synthase D 1.14.99.2 kynurenine 7,8-hydroxylase D 1.14.99.3 heme oxygenase D 1.14.99.4 progesterone monooxygenase D 1.14.99.9 steroid 17alpha-monooxygenase D 1.14.99.10 steroid 21-monooxygenase D 1.14.99.11 estradiol 6beta-monooxygenase D 1.14.99.12 androst-4-ene-3,17-dione monooxygenase D 1.14.99.14 progesterone 11alpha-monooxygenase D 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating) D 1.14.99.19 plasmanylethanolamine desaturase D 1.14.99.20 phylloquinone monooxygenase (2,3-epoxidizing) D 1.14.99.21 Latia-luciferin monooxygenase (demethylating) D 1.14.99.22 ecdysone 20-monooxygenase D 1.14.99.23 3-hydroxybenzoate 2-monooxygenase D 1.14.99.24 steroid 9alpha-monooxygenase D 1.14.99.26 2-hydroxypyridine 5-monooxygenase D 1.14.99.27 juglone 3-monooxygenase D 1.14.99.29 deoxyhypusine monooxygenase D 1.14.99.31 myristoyl-CoA 11-(E) desaturase D 1.14.99.32 myristoyl-CoA 11-(Z) desaturase D 1.14.99.33 Delta12-fatty acid dehydrogenase D 1.14.99.34 monoprenyl isoflavone epoxidase D 1.14.99.35 thiophene-2-carbonyl-CoA monooxygenase D 1.14.99.36 beta-carotene 15,15'-monooxygenase D 1.14.99.37 taxadiene 5alpha-hydroxylase D 1.14.99.38 cholesterol 25-hydroxylase D 1.14.99.39 ammonia monooxygenase D 1.14.99.40 5,6-dimethylbenzimidazole synthase D 1.14.99.41 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase D 1.14.99.42 zeaxanthin 7,8-dioxygenase D 1.14.99.43 beta-amyrin 24-hydroxylase D 1.14.99.44 diapolycopene oxygenase D 1.14.99.45 carotene epsilon-monooxygenase D 1.14.99.46 pyrimidine oxygenase D 1.14.99.47 (+)-larreatricin hydroxylase D 1.14.99.- C 1.14.- Acting on paired donors with incorporation of molecular oxygen D 1.14.-.- B 1.15 Acting on superoxide as acceptor C 1.15.1 Acting on superoxide as acceptor (only sub-subclass identified to date) D 1.15.1.1 superoxide dismutase E PRU_1727 sodB; superoxide dismutase K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] D 1.15.1.2 superoxide reductase C 1.15.- Acting on superoxide as acceptor D 1.15.-.- B 1.16 Oxidizing metal ions C 1.16.1 With NAD+ or NADP+ as acceptor D 1.16.1.1 mercury(II) reductase D 1.16.1.2 diferric-transferrin reductase D 1.16.1.3 aquacobalamin reductase D 1.16.1.4 cob(II)alamin reductase D 1.16.1.5 aquacobalamin reductase (NADPH) D 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating) D 1.16.1.7 ferric-chelate reductase (NADH) D 1.16.1.8 [methionine synthase] reductase D 1.16.1.9 ferric-chelate reductase (NADPH) D 1.16.1.- C 1.16.3 With oxygen as acceptor D 1.16.3.1 ferroxidase C 1.16.5 With a quinone or similar compound as acceptor D 1.16.5.1 ascorbate ferrireductase (transmembrane) C 1.16.8 With a flavin as acceptor D 1.16.8.1 cob(II)yrinic acid a,c-diamide reductase C 1.16.9 With a copper protein as acceptor D 1.16.9.1 iron:rusticyanin reductase B 1.17 Acting on CH or CH2 groups C 1.17.1 With NAD+ or NADP+ as acceptor D 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase D 1.17.1.2 4-hydroxy-3-methylbut-2-enyl diphosphate reductase E PRU_0161 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 E1.17.1.2; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [EC:1.17.1.2] D 1.17.1.3 leucoanthocyanidin reductase D 1.17.1.4 xanthine dehydrogenase D 1.17.1.5 nicotinate dehydrogenase D 1.17.1.7 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase D 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase E PRU_2449 dapB; dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] C 1.17.2 With a cytochrome as acceptor D 1.17.2.1 nicotinate dehydrogenase (cytochrome) D 1.17.2.2 lupanine 17-hydroxylase (cytochrome c) C 1.17.3 With oxygen as acceptor D 1.17.3.1 pteridine oxidase D 1.17.3.2 xanthine oxidase D 1.17.3.3 6-hydroxynicotinate dehydrogenase C 1.17.4 With a disulfide as acceptor D 1.17.4.1 ribonucleoside-diphosphate reductase D 1.17.4.2 ribonucleoside-triphosphate reductase E PRU_1366 nrdD_1; anaerobic ribonucleoside-triphosphate reductase K00527 nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2] E PRU_2851 nrdD_2; anaerobic ribonucleoside-triphosphate reductase K00527 nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2] C 1.17.5 With a quinone or similar compound as acceptor D 1.17.5.1 phenylacetyl-CoA dehydrogenase D 1.17.5.2 caffeine dehydrogenase D 1.17.5.- C 1.17.7 With an iron-sulfur protein as acceptor D 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase E PRU_2858 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 E1.17.7.1; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1] D 1.17.7.2 7-hydroxymethyl chlorophyll a reductase C 1.17.99 With other acceptors D 1.17.99.1 4-methylphenol dehydrogenase (hydroxylating) D 1.17.99.2 ethylbenzene hydroxylase D 1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase D 1.17.99.4 uracil/thymine dehydrogenase D 1.17.99.5 bile-acid 7alpha-dehydroxylase C 1.17.- Acting on CH or CH2 groups D 1.17.-.- B 1.18 Acting on iron-sulfur proteins as donors C 1.18.1 With NAD+ or NADP+ as acceptor D 1.18.1.1 rubredoxin---NAD+ reductase D 1.18.1.2 ferredoxin---NADP+ reductase D 1.18.1.3 ferredoxin---NAD+ reductase D 1.18.1.4 rubredoxin---NAD(P)+ reductase D 1.18.1.5 putidaredoxin---NAD+ reductase D 1.18.1.6 adrenodoxin-NADP+ reductase D 1.18.1.- C 1.18.6 With dinitrogen as acceptor D 1.18.6.1 nitrogenase C 1.18.- Acting on iron-sulfur proteins as donors D 1.18.-.- B 1.19 Acting on reduced flavodoxin as donor C 1.19.6 With dinitrogen as acceptor D 1.19.6.1 nitrogenase (flavodoxin) D 1.19.6.- B 1.20 Acting on phosphorus or arsenic in donors C 1.20.1 With NAD+ or NADP+ as acceptor D 1.20.1.1 phosphonate dehydrogenase C 1.20.2 With a cytochrome as acceptor D 1.20.2.1 arsenate reductase (cytochrome c) C 1.20.4 With disulfide as acceptor D 1.20.4.1 arsenate reductase (glutaredoxin) D 1.20.4.2 methylarsonate reductase D 1.20.4.3 mycoredoxin C 1.20.9 With a copper protein as acceptor D 1.20.9.1 arsenate reductase (azurin) C 1.20.99 With other acceptors D 1.20.99.1 arsenate reductase (donor) B 1.21 Acting on X-H and Y-H to form an X-Y bond C 1.21.3 With oxygen as acceptor D 1.21.3.1 isopenicillin-N synthase D 1.21.3.2 columbamine oxidase D 1.21.3.3 reticuline oxidase D 1.21.3.4 sulochrin oxidase [(+)-bisdechlorogeodin-forming] D 1.21.3.5 sulochrin oxidase [(-)-bisdechlorogeodin-forming] D 1.21.3.6 aureusidin synthase D 1.21.3.7 tetrahydrocannabinolic acid synthase D 1.21.3.8 cannabidiolic acid synthase C 1.21.4 With a disulfide as acceptor D 1.21.4.1 D-proline reductase (dithiol) D 1.21.4.2 glycine reductase D 1.21.4.3 sarcosine reductase D 1.21.4.4 betaine reductase C 1.21.99 With other acceptors D 1.21.99.1 beta-cyclopiazonate dehydrogenase C 1.21.- Acting on X-H and Y-H to form an X-Y bond D 1.21.-.- B 1.22 Acting on halogen in donors C 1.22.1 With NAD+ or NADP+ as acceptor D 1.22.1.1 iodotyrosine deiodinase B 1.23 Reducing C-O-C group as acceptor C 1.23.1 With NADH or NADPH as donor (only sub-subclass identified to date) D 1.23.1.1 (+)-pinoresinol reductase D 1.23.1.2 (+)-lariciresinol reductase D 1.23.1.3 (-)-pinoresinol reductase D 1.23.1.4 (-)-lariciresinol reductase D 1.23.1.- B 1.97 Other oxidoreductases C 1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses D 1.97.1.1 chlorate reductase D 1.97.1.2 pyrogallol hydroxytransferase D 1.97.1.4 [formate-C-acetyltransferase]-activating enzyme E PRU_1365 nrdG_1; anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] E PRU_2852 nrdG_2; anaerobic ribonucleoside-triphosphate reductase activating protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] E PRU_1536 radical SAM domain-containing protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] E PRU_1244 pflA; pyruvate formate-lyase activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] E PRU_0572 radical SAM domain-containing protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] E PRU_0136 lyase domain-containing protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D 1.97.1.8 tetrachloroethene reductive dehalogenase D 1.97.1.9 selenate reductase D 1.97.1.10 thyroxine 5'-deiodinase D 1.97.1.11 thyroxine 5-deiodinase D 1.97.1.12 photosystem I D 1.97.1.- B 1.- C 1.-.- D 1.-.-.- # A2. Transferases B 2.1 Transferring one-carbon groups C 2.1.1 Methyltransferases D 2.1.1.1 nicotinamide N-methyltransferase D 2.1.1.2 guanidinoacetate N-methyltransferase D 2.1.1.3 thetin---homocysteine S-methyltransferase D 2.1.1.4 acetylserotonin O-methyltransferase D 2.1.1.5 betaine---homocysteine S-methyltransferase D 2.1.1.6 catechol O-methyltransferase D 2.1.1.7 nicotinate N-methyltransferase D 2.1.1.8 histamine N-methyltransferase D 2.1.1.9 thiol S-methyltransferase D 2.1.1.10 homocysteine S-methyltransferase D 2.1.1.11 magnesium protoporphyrin IX methyltransferase D 2.1.1.12 methionine S-methyltransferase D 2.1.1.13 methionine synthase E PRU_0799 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D 2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase D 2.1.1.15 fatty-acid O-methyltransferase D 2.1.1.16 methylene-fatty-acyl-phospholipid synthase D 2.1.1.17 phosphatidylethanolamine N-methyltransferase D 2.1.1.18 polysaccharide O-methyltransferase D 2.1.1.19 trimethylsulfonium---tetrahydrofolate N-methyltransferase D 2.1.1.20 glycine N-methyltransferase D 2.1.1.21 methylamine---glutamate N-methyltransferase D 2.1.1.22 carnosine N-methyltransferase D 2.1.1.25 phenol O-methyltransferase D 2.1.1.26 iodophenol O-methyltransferase D 2.1.1.27 tyramine N-methyltransferase D 2.1.1.28 phenylethanolamine N-methyltransferase D 2.1.1.33 tRNA (guanine46-N7)-methyltransferase E PRU_0163 tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D 2.1.1.34 tRNA (guanosine18-2'-O)-methyltransferase D 2.1.1.35 tRNA (uracil54-C5)-methyltransferase D 2.1.1.37 DNA (cytosine-5-)-methyltransferase E PRU_0938 prophage PRU01 DNA methylase K00558 E2.1.1.37; DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] E PRU_0361 C-5 cytosine-specific family DNA methylase K00558 E2.1.1.37; DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] E PRU_0362 C-5 cytosine-specific family DNA methylase K00558 E2.1.1.37; DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] E PRU_0666 C-5 cytosine-specific family DNA methylase K00558 E2.1.1.37; DNA (cytosine-5-)-methyltransferase [EC:2.1.1.37] D 2.1.1.38 O-demethylpuromycin O-methyltransferase D 2.1.1.39 inositol 3-methyltransferase D 2.1.1.40 inositol 1-methyltransferase D 2.1.1.41 sterol 24-C-methyltransferase D 2.1.1.42 flavone 3'-O-methyltransferase D 2.1.1.43 histone-lysine N-methyltransferase D 2.1.1.44 dimethylhistidine N-methyltransferase D 2.1.1.45 thymidylate synthase E PRU_1278 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D 2.1.1.46 isoflavone 4'-O-methyltransferase D 2.1.1.47 indolepyruvate C-methyltransferase D 2.1.1.49 amine N-methyltransferase D 2.1.1.50 loganate O-methyltransferase D 2.1.1.53 putrescine N-methyltransferase D 2.1.1.54 deoxycytidylate C-methyltransferase D 2.1.1.55 tRNA (adenine-N6-)-methyltransferase D 2.1.1.56 mRNA (guanine-N7)-methyltransferase D 2.1.1.57 mRNA (nucleoside-2'-O)-methyltransferase D 2.1.1.59 [cytochrome c]-lysine N-methyltransferase D 2.1.1.60 calmodulin-lysine N-methyltransferase D 2.1.1.61 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase D 2.1.1.62 mRNA (2'-O-methyladenosine-N6-)-methyltransferase D 2.1.1.63 methylated-DNA---[protein]-cysteine S-methyltransferase D 2.1.1.64 3-demethylubiquinol 3-O-methyltransferase D 2.1.1.65 licodione 2'-O-methyltransferase D 2.1.1.66 rRNA (adenosine-2'-O-)-methyltransferase D 2.1.1.67 thiopurine S-methyltransferase D 2.1.1.68 caffeate O-methyltransferase D 2.1.1.69 5-hydroxyfuranocoumarin 5-O-methyltransferase D 2.1.1.70 8-hydroxyfuranocoumarin 8-O-methyltransferase D 2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase D 2.1.1.72 site-specific DNA-methyltransferase (adenine-specific) E PRU_2887 type I restriction-modification system subunit M K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] E PRU_1005 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] D 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing) D 2.1.1.75 apigenin 4'-O-methyltransferase D 2.1.1.76 quercetin 3-O-methyltransferase D 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase D 2.1.1.78 isoorientin 3'-O-methyltransferase D 2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase D 2.1.1.80 protein-glutamate O-methyltransferase D 2.1.1.82 3-methylquercetin 7-O-methyltransferase D 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase D 2.1.1.84 methylquercetagetin 6-O-methyltransferase D 2.1.1.85 protein-histidine N-methyltransferase D 2.1.1.86 tetrahydromethanopterin S-methyltransferase D 2.1.1.87 pyridine N-methyltransferase D 2.1.1.88 8-hydroxyquercetin 8-O-methyltransferase D 2.1.1.89 tetrahydrocolumbamine 2-O-methyltransferase D 2.1.1.90 methanol---corrinoid protein Co-methyltransferase D 2.1.1.91 isobutyraldoxime O-methyltransferase D 2.1.1.94 tabersonine 16-O-methyltransferase D 2.1.1.95 tocopherol O-methyltransferase D 2.1.1.96 thioether S-methyltransferase D 2.1.1.97 3-hydroxyanthranilate 4-C-methyltransferase D 2.1.1.98 diphthine synthase D 2.1.1.99 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase D 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase D 2.1.1.101 macrocin O-methyltransferase D 2.1.1.102 demethylmacrocin O-methyltransferase D 2.1.1.103 phosphoethanolamine N-methyltransferase D 2.1.1.104 caffeoyl-CoA O-methyltransferase D 2.1.1.105 N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase D 2.1.1.106 tryptophan 2-C-methyltransferase D 2.1.1.107 uroporphyrinogen-III C-methyltransferase D 2.1.1.108 6-hydroxymellein O-methyltransferase D 2.1.1.109 demethylsterigmatocystin 6-O-methyltransferase D 2.1.1.110 sterigmatocystin 8-O-methyltransferase D 2.1.1.111 anthranilate N-methyltransferase D 2.1.1.112 glucuronoxylan 4-O-methyltransferase D 2.1.1.113 site-specific DNA-methyltransferase (cytosine-N4-specific) D 2.1.1.114 polyprenyldihydroxybenzoate methyltransferase D 2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase D 2.1.1.116 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase D 2.1.1.117 (S)-scoulerine 9-O-methyltransferase D 2.1.1.118 columbamine O-methyltransferase D 2.1.1.119 10-hydroxydihydrosanguinarine 10-O-methyltransferase D 2.1.1.120 12-hydroxydihydrochelirubine 12-O-methyltransferase D 2.1.1.121 6-O-methylnorlaudanosoline 5'-O-methyltransferase D 2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferase D 2.1.1.123 [cytochrome-c]-methionine S-methyltransferase D 2.1.1.124 [cytochrome c]-arginine N-methyltransferase D 2.1.1.125 histone-arginine N-methyltransferase D 2.1.1.126 [myelin basic protein]-arginine N-methyltransferase D 2.1.1.127 [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase D 2.1.1.128 (RS)-norcoclaurine 6-O-methyltransferase D 2.1.1.129 inositol 4-methyltransferase D 2.1.1.130 precorrin-2 C20-methyltransferase D 2.1.1.131 precorrin-3B C17-methyltransferase E PRU_1082 cobJH; precorrin-3B C17-methyltransferase/precorrin-8X methylmutase K05934 E2.1.1.131; precorrin-3B C17-methyltransferase [EC:2.1.1.131] D 2.1.1.132 precorrin-6B C5,15-methyltransferase (decarboxylating) E PRU_1087 cobL; precorrin-6Y C5,15-methyltransferase K00595 cobL; precorrin-6Y C5,15-methyltransferase (decarboxylating) [EC:2.1.1.132] D 2.1.1.133 precorrin-4 C11-methyltransferase D 2.1.1.136 chlorophenol O-methyltransferase D 2.1.1.137 arsenite methyltransferase D 2.1.1.139 3'-demethylstaurosporine O-methyltransferase D 2.1.1.140 (S)-coclaurine-N-methyltransferase D 2.1.1.141 jasmonate O-methyltransferase D 2.1.1.142 cycloartenol 24-C-methyltransferase D 2.1.1.143 24-methylenesterol C-methyltransferase D 2.1.1.144 trans-aconitate 2-methyltransferase D 2.1.1.145 trans-aconitate 3-methyltransferase D 2.1.1.146 (iso)eugenol O-methyltransferase D 2.1.1.147 corydaline synthase D 2.1.1.148 thymidylate synthase (FAD) D 2.1.1.150 isoflavone 7-O-methyltransferase D 2.1.1.151 cobalt-factor II C20-methyltransferase D 2.1.1.152 precorrin-6A synthase (deacetylating) D 2.1.1.153 vitexin 2''-O-rhamnoside 7-O-methyltransferase D 2.1.1.154 isoliquiritigenin 2'-O-methyltransferase D 2.1.1.155 kaempferol 4'-O-methyltransferase D 2.1.1.156 glycine/sarcosine N-methyltransferase D 2.1.1.157 sarcosine/dimethylglycine N-methyltransferase D 2.1.1.158 7-methylxanthosine synthase D 2.1.1.159 theobromine synthase D 2.1.1.160 caffeine synthase D 2.1.1.161 dimethylglycine N-methyltransferase D 2.1.1.162 glycine/sarcosine/dimethylglycine N-methyltransferase D 2.1.1.163 demethylmenaquinone methyltransferase E PRU_0722 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase [EC:2.1.1.163 2.1.1.201] D 2.1.1.164 demethylrebeccamycin-D-glucose O-methyltransferase D 2.1.1.165 methyl halide transferase D 2.1.1.166 23S rRNA (uridine2552-2'-O)-methyltransferase D 2.1.1.167 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase D 2.1.1.168 21S rRNA (uridine2791-2'-O)-methyltransferase D 2.1.1.169 tricetin 3',4',5'-O-trimethyltransferase D 2.1.1.170 16S rRNA (guanine527-N7)-methyltransferase E PRU_1653 gidB; methyltransferase GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D 2.1.1.171 16S rRNA (guanine966-N2)-methyltransferase D 2.1.1.172 16S rRNA (guanine1207-N2)-methyltransferase D 2.1.1.173 23S rRNA (guanine2445-N2)-methyltransferase D 2.1.1.174 23S rRNA (guanine1835-N2)-methyltransferase D 2.1.1.175 tricin synthase D 2.1.1.176 16S rRNA (cytosine967-C5)-methyltransferase D 2.1.1.177 23S rRNA (pseudouridine1915-N3)-methyltransferase E PRU_0727 hypothetical protein K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D 2.1.1.178 16S rRNA (cytosine1407-C5)-methyltransferase D 2.1.1.179 16S rRNA (guanine1405-N7)-methyltransferase D 2.1.1.180 16S rRNA (adenine1408-N1)-methyltransferase D 2.1.1.181 23S rRNA (adenine1618-N6)-methyltransferase D 2.1.1.182 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase E PRU_1549 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D 2.1.1.183 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase D 2.1.1.184 23S rRNA (adenine2085-N6)-dimethyltransferase D 2.1.1.185 23S rRNA (guanosine2251-2'-O)-methyltransferase D 2.1.1.186 23S rRNA (cytidine2498-2'-O)-methyltransferase D 2.1.1.187 23S rRNA (guanine745-N1)-methyltransferase D 2.1.1.188 23S rRNA (guanine748-N1)-methyltransferase D 2.1.1.189 23S rRNA (uracil747-C5)-methyltransferase D 2.1.1.190 23S rRNA (uracil1939-C5)-methyltransferase D 2.1.1.191 23S rRNA (cytosine1962-C5)-methyltransferase E PRU_0904 PUA domain-containing protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D 2.1.1.192 23S rRNA (adenine2503-C2)-methyltransferase E PRU_1562 rlmN; 23S rRNA m2A2503 methyltransferase K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D 2.1.1.193 16S rRNA (uracil1498-N3)-methyltransferase E PRU_1064 hypothetical protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D 2.1.1.195 cobalt-precorrin-5B (C1)-methyltransferase E PRU_1089 cobKD; precorrin-6x reductase/cobalamin biosynthetic protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D 2.1.1.196 cobalt-precorrin-7 (C15)-methyltransferase [decarboxylating] D 2.1.1.197 malonyl-CoA O-methyltransferase D 2.1.1.198 16S rRNA (cytidine1402-2'-O)-methyltransferase E PRU_1869 hypothetical protein K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D 2.1.1.199 16S rRNA (cytosine1402-N4)-methyltransferase E PRU_2325 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D 2.1.1.200 tRNA (cytidine32/uridine32-2'-O)-methyltransferase D 2.1.1.201 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase E PRU_0722 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase K03183 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase [EC:2.1.1.163 2.1.1.201] D 2.1.1.202 multisite-specific tRNA:(cytosine-C5)-methyltransferase D 2.1.1.203 tRNA (cytosine34-C5)-methyltransferase D 2.1.1.204 tRNA (cytosine38-C5)-methyltransferase D 2.1.1.205 tRNA (cytidine32/guanosine34-2'-O)-methyltransferase D 2.1.1.206 tRNA (cytidine56-2'-O)-methyltransferase D 2.1.1.207 tRNA (cytidine34-2'-O)-methyltransferase D 2.1.1.208 23S rRNA (uridine2479-2'-O)-methyltransferase D 2.1.1.209 23S rRNA (guanine2535-N1)-methyltransferase D 2.1.1.210 demethylspheroidene O-methyltransferase D 2.1.1.211 tRNASer (uridine44-2'-O)-methyltransferase D 2.1.1.212 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase D 2.1.1.213 tRNA (guanine10-N2)-dimethyltransferase D 2.1.1.214 tRNA (guanine10-N2)-methyltransferase D 2.1.1.215 tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase D 2.1.1.216 tRNA (guanine26-N2)-dimethyltransferase D 2.1.1.217 tRNA (adenine22-N1)-methyltransferase D 2.1.1.218 tRNA (adenine9-N1)-methyltransferase D 2.1.1.219 tRNA (adenine57-N1/adenine58-N1)-methyltransferase D 2.1.1.220 tRNA (adenine58-N1)-methyltransferase D 2.1.1.221 tRNA (guanine9-N1)-methyltransferase D 2.1.1.222 2-polyprenyl-6-hydroxyphenyl methylase D 2.1.1.223 tRNA1Val (adenine37-N6)-methyltransferase E PRU_0841 hypothetical protein K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223] D 2.1.1.224 23S rRNA (adenine2503-C8)-methyltransferase D 2.1.1.225 tRNA:m4X modification enzyme D 2.1.1.226 23S rRNA (cytidine1920-2'-O)-methyltransferase D 2.1.1.227 16S rRNA (cytidine1409-2'-O)-methyltransferase D 2.1.1.228 tRNA (guanine37-N1)-methyltransferase E PRU_0564 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D 2.1.1.229 tRNA (carboxymethyluridine34-5-O)-methyltransferase D 2.1.1.230 23S rRNA (adenosine1067-2'-O)-methyltransferase D 2.1.1.231 flavonoid 4'-O-methyltransferase D 2.1.1.232 naringenin 7-O-methyltransferase D 2.1.1.233 [phosphatase 2A protein]-leucine-carboxy methyltransferase D 2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase D 2.1.1.235 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase D 2.1.1.236 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase D 2.1.1.237 mycinamicin III 3''-O-methyltransferase D 2.1.1.238 mycinamicin VI 2''-O-methyltransferase D 2.1.1.239 L-olivosyl-oleandolide 3-O-methyltransferase D 2.1.1.240 trans-resveratrol di-O-methyltransferase D 2.1.1.241 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase D 2.1.1.242 16S rRNA (guanine1516-N2)-methyltransferase D 2.1.1.243 2-ketoarginine methyltransferase D 2.1.1.244 protein N-terminal methyltransferase D 2.1.1.245 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase D 2.1.1.246 [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase D 2.1.1.247 [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase D 2.1.1.248 methylamine---corrinoid protein Co-methyltransferase D 2.1.1.249 dimethylamine---corrinoid protein Co-methyltransferase D 2.1.1.250 trimethylamine---corrinoid protein Co-methyltransferase D 2.1.1.251 methylated-thiol---coenzyme M methyltransferase D 2.1.1.252 tetramethylammonium---corrinoid protein Co-methyltransferase D 2.1.1.253 [methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme M methyltransferase D 2.1.1.254 erythromycin 3''-O-methyltransferase D 2.1.1.255 geranyl diphosphate 2-C-methyltransferase D 2.1.1.256 tRNA (guanine6-N2)-methyltransferase D 2.1.1.257 tRNA (pseudouridine54-N1)-methyltransferase D 2.1.1.258 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase D 2.1.1.259 [fructose-bisphosphate aldolase]-lysine N-methyltransferase D 2.1.1.260 rRNA small subunit pseudouridine methyltransferase Nep1 D 2.1.1.261 4-dimethylallyltryptophan N-methyltransferase D 2.1.1.262 squalene methyltransferase D 2.1.1.263 botryococcene C-methyltransferase D 2.1.1.264 23S rRNA (guanine2069-N7)-methyltransferase D 2.1.1.265 tellurite methyltransferase D 2.1.1.266 23S rRNA (adenine2030-N6)-methyltransferase D 2.1.1.267 flavonoid 3',5'-methyltransferase D 2.1.1.268 tRNAThr (cytosine32-N3)-methyltransferase D 2.1.1.- E PRU_1041 TrmH family RNA methyltransferase K00599 E2.1.1.- E PRU_1513 rumA; 23S rRNA (uracil-5-)-methyltransferase RumA K00599 E2.1.1.- E PRU_2398 modification methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.-] E PRU_1028 prmA; 50S ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-] E PRU_1805 THUMP domain-containing protein K07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-] C 2.1.2 Hydroxymethyl-, formyl- and related transferases D 2.1.2.1 glycine hydroxymethyltransferase E PRU_0635 glyA; glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D 2.1.2.2 phosphoribosylglycinamide formyltransferase E PRU_0175 purT; phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2] E PRU_2043 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase E PRU_1709 IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] E PRU_1927 phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D 2.1.2.4 glycine formimidoyltransferase D 2.1.2.5 glutamate formimidoyltransferase D 2.1.2.7 D-alanine 2-hydroxymethyltransferase D 2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase D 2.1.2.9 methionyl-tRNA formyltransferase E PRU_0234 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D 2.1.2.10 aminomethyltransferase E PRU_2048 gcvT; aminomethyltransferase K00605 gcvT; aminomethyltransferase [EC:2.1.2.10] D 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase E PRU_2450 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D 2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase D 2.1.2.- C 2.1.3 Carboxy- and carbamoyltransferases D 2.1.3.1 methylmalonyl-CoA carboxytransferase D 2.1.3.2 aspartate carbamoyltransferase E PRU_0637 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D 2.1.3.3 ornithine carbamoyltransferase D 2.1.3.5 oxamate carbamoyltransferase D 2.1.3.6 putrescine carbamoyltransferase D 2.1.3.7 3-hydroxymethylcephem carbamoyltransferase D 2.1.3.8 lysine carbamoyltransferase D 2.1.3.9 N-acetylornithine carbamoyltransferase D 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase D 2.1.3.11 N-succinylornithine carbamoyltransferase E PRU_2210 transcarbamylase K13043 argF2; N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11] D 2.1.3.- C 2.1.4 Amidinotransferases D 2.1.4.1 glycine amidinotransferase D 2.1.4.2 scyllo-inosamine-4-phosphate amidinotransferase C 2.1.- Transferring one-carbon groups D 2.1.-.- B 2.2 Transferring aldehyde or ketonic groups C 2.2.1 Transketolases and transaldolases D 2.2.1.1 transketolase E PRU_0393 transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D 2.2.1.2 transaldolase D 2.2.1.3 formaldehyde transketolase D 2.2.1.4 acetoin---ribose-5-phosphate transaldolase D 2.2.1.5 2-hydroxy-3-oxoadipate synthase D 2.2.1.6 acetolactate synthase E PRU_1077 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] E PRU_1076 ilvN; acetolactate synthase small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] D 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase E PRU_2883 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D 2.2.1.8 fluorothreonine transaldolase D 2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase E PRU_1685 menD; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9] D 2.2.1.10 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase D 2.2.1.11 6-deoxy-5-ketofructose 1-phosphate synthase D 2.2.1.- B 2.3 Acyltransferases C 2.3.1 Transferring groups other than aminoacyl groups D 2.3.1.1 amino-acid N-acetyltransferase D 2.3.1.2 imidazole N-acetyltransferase D 2.3.1.3 glucosamine N-acetyltransferase D 2.3.1.4 glucosamine-phosphate N-acetyltransferase D 2.3.1.5 arylamine N-acetyltransferase D 2.3.1.6 choline O-acetyltransferase D 2.3.1.7 carnitine O-acetyltransferase D 2.3.1.8 phosphate acetyltransferase E PRU_2260 pta; phosphate acetyltransferase K00625 E2.3.1.8; phosphate acetyltransferase [EC:2.3.1.8] D 2.3.1.9 acetyl-CoA C-acetyltransferase D 2.3.1.10 hydrogen-sulfide S-acetyltransferase D 2.3.1.11 thioethanolamine S-acetyltransferase D 2.3.1.12 dihydrolipoyllysine-residue acetyltransferase D 2.3.1.13 glycine N-acyltransferase D 2.3.1.14 glutamine N-phenylacetyltransferase D 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase D 2.3.1.16 acetyl-CoA C-acyltransferase D 2.3.1.17 aspartate N-acetyltransferase D 2.3.1.18 galactoside O-acetyltransferase D 2.3.1.19 phosphate butyryltransferase E PRU_2350 phosphate butyryltransferase K00634 ptb; phosphate butyryltransferase [EC:2.3.1.19] D 2.3.1.20 diacylglycerol O-acyltransferase D 2.3.1.21 carnitine O-palmitoyltransferase D 2.3.1.22 2-acylglycerol O-acyltransferase D 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase D 2.3.1.24 sphingosine N-acyltransferase D 2.3.1.25 plasmalogen synthase D 2.3.1.26 sterol O-acyltransferase D 2.3.1.27 cortisol O-acetyltransferase D 2.3.1.28 chloramphenicol O-acetyltransferase E PRU_0509 chloramphenicol O-acetyltransferase K00638 E2.3.1.28; chloramphenicol O-acetyltransferase [EC:2.3.1.28] D 2.3.1.29 glycine C-acetyltransferase D 2.3.1.30 serine O-acetyltransferase E PRU_2687 bacterial transferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] E PRU_1565 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] E PRU_1528 serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D 2.3.1.31 homoserine O-acetyltransferase D 2.3.1.32 lysine N-acetyltransferase D 2.3.1.33 histidine N-acetyltransferase D 2.3.1.34 D-tryptophan N-acetyltransferase D 2.3.1.35 glutamate N-acetyltransferase D 2.3.1.36 D-amino-acid N-acetyltransferase D 2.3.1.37 5-aminolevulinate synthase D 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase D 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase E PRU_0675 fabD D 2.3.1.40 acyl-[acyl-carrier-protein]---phospholipid O-acyltransferase D 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I D 2.3.1.42 glycerone-phosphate O-acyltransferase D 2.3.1.43 phosphatidylcholine---sterol O-acyltransferase D 2.3.1.44 N-acetylneuraminate 4-O-acetyltransferase D 2.3.1.45 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase D 2.3.1.46 homoserine O-succinyltransferase E PRU_0609 metA; homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase [EC:2.3.1.46] D 2.3.1.47 8-amino-7-oxononanoate synthase D 2.3.1.48 histone acetyltransferase D 2.3.1.49 deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase D 2.3.1.50 serine C-palmitoyltransferase D 2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase E PRU_1611 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D 2.3.1.52 2-acylglycerol-3-phosphate O-acyltransferase D 2.3.1.53 phenylalanine N-acetyltransferase D 2.3.1.54 formate C-acetyltransferase E PRU_1537 pyruvate formate lyase family protein K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] E PRU_1243 pflB; formate C-acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D 2.3.1.56 aromatic-hydroxylamine O-acetyltransferase D 2.3.1.57 diamine N-acetyltransferase E PRU_0894 speG; spermidine N(1)-acetyltransferase K00657 E2.3.1.57; diamine N-acetyltransferase [EC:2.3.1.57] D 2.3.1.58 2,3-diaminopropionate N-oxalyltransferase D 2.3.1.59 gentamicin 2'-N-acetyltransferase D 2.3.1.60 gentamicin 3'-N-acetyltransferase D 2.3.1.61 dihydrolipoyllysine-residue succinyltransferase D 2.3.1.62 2-acylglycerophosphocholine O-acyltransferase D 2.3.1.63 1-alkylglycerophosphocholine O-acyltransferase D 2.3.1.64 agmatine N4-coumaroyltransferase D 2.3.1.65 bile acid-CoA:amino acid N-acyltransferase D 2.3.1.66 leucine N-acetyltransferase D 2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase D 2.3.1.68 glutamine N-acyltransferase D 2.3.1.69 monoterpenol O-acetyltransferase D 2.3.1.71 glycine N-benzoyltransferase D 2.3.1.72 indoleacetylglucose---inositol O-acyltransferase D 2.3.1.73 diacylglycerol---sterol O-acyltransferase D 2.3.1.74 naringenin-chalcone synthase D 2.3.1.75 long-chain-alcohol O-fatty-acyltransferase D 2.3.1.76 retinol O-fatty-acyltransferase D 2.3.1.77 triacylglycerol---sterol O-acyltransferase D 2.3.1.78 heparan-alpha-glucosaminide N-acetyltransferase D 2.3.1.79 maltose O-acetyltransferase D 2.3.1.80 cysteine-S-conjugate N-acetyltransferase D 2.3.1.81 aminoglycoside N3'-acetyltransferase D 2.3.1.82 aminoglycoside N6'-acetyltransferase D 2.3.1.83 phosphatidylcholine---dolichol O-acyltransferase D 2.3.1.84 alcohol O-acetyltransferase D 2.3.1.85 fatty-acid synthase D 2.3.1.86 fatty-acyl-CoA synthase D 2.3.1.87 aralkylamine N-acetyltransferase D 2.3.1.88 peptide alpha-N-acetyltransferase D 2.3.1.89 tetrahydrodipicolinate N-acetyltransferase D 2.3.1.90 beta-glucogallin O-galloyltransferase D 2.3.1.91 sinapoylglucose---choline O-sinapoyltransferase D 2.3.1.92 sinapoylglucose---malate O-sinapoyltransferase D 2.3.1.93 13-hydroxylupanine O-tigloyltransferase D 2.3.1.94 6-deoxyerythronolide-B synthase D 2.3.1.95 trihydroxystilbene synthase D 2.3.1.96 glycoprotein N-palmitoyltransferase D 2.3.1.97 glycylpeptide N-tetradecanoyltransferase D 2.3.1.98 chlorogenate---glucarate O-hydroxycinnamoyltransferase D 2.3.1.99 quinate O-hydroxycinnamoyltransferase D 2.3.1.100 [myelin-proteolipid] O-palmitoyltransferase D 2.3.1.101 formylmethanofuran---tetrahydromethanopterin N-formyltransferase D 2.3.1.102 N6-hydroxylysine O-acetyltransferase D 2.3.1.103 sinapoylglucose---sinapoylglucose O-sinapoyltransferase D 2.3.1.105 alkylglycerophosphate 2-O-acetyltransferase D 2.3.1.106 tartronate O-hydroxycinnamoyltransferase D 2.3.1.107 deacetylvindoline O-acetyltransferase D 2.3.1.108 alpha-tubulin N-acetyltransferase D 2.3.1.109 arginine N-succinyltransferase D 2.3.1.110 tyramine N-feruloyltransferase D 2.3.1.111 mycocerosate synthase D 2.3.1.112 D-tryptophan N-malonyltransferase D 2.3.1.113 anthranilate N-malonyltransferase D 2.3.1.114 3,4-dichloroaniline N-malonyltransferase D 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase D 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase D 2.3.1.117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase D 2.3.1.118 N-hydroxyarylamine O-acetyltransferase D 2.3.1.119 icosanoyl-CoA synthase D 2.3.1.121 1-alkenylglycerophosphoethanolamine O-acyltransferase D 2.3.1.122 trehalose O-mycolyltransferase D 2.3.1.123 dolichol O-acyltransferase D 2.3.1.125 1-alkyl-2-acetylglycerol O-acyltransferase D 2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase D 2.3.1.127 ornithine N-benzoyltransferase D 2.3.1.128 ribosomal-protein-alanine N-acetyltransferase D 2.3.1.129 acyl-[acyl-carrier-protein]---UDP-N-acetylglucosamine O-acyltransferase E PRU_1846 acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] E PRU_0706 lpxA; acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D 2.3.1.130 galactarate O-hydroxycinnamoyltransferase D 2.3.1.131 glucarate O-hydroxycinnamoyltransferase D 2.3.1.132 glucarolactone O-hydroxycinnamoyltransferase D 2.3.1.133 shikimate O-hydroxycinnamoyltransferase D 2.3.1.134 galactolipid O-acyltransferase D 2.3.1.135 phosphatidylcholine---retinol O-acyltransferase D 2.3.1.136 polysialic-acid O-acetyltransferase D 2.3.1.137 carnitine O-octanoyltransferase D 2.3.1.138 putrescine N-hydroxycinnamoyltransferase D 2.3.1.139 ecdysone O-acyltransferase D 2.3.1.140 rosmarinate synthase D 2.3.1.141 galactosylacylglycerol O-acyltransferase D 2.3.1.142 glycoprotein O-fatty-acyltransferase D 2.3.1.143 beta-glucogallin---tetrakisgalloylglucose O-galloyltransferase D 2.3.1.144 anthranilate N-benzoyltransferase D 2.3.1.145 piperidine N-piperoyltransferase D 2.3.1.146 pinosylvin synthase D 2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent) D 2.3.1.148 glycerophospholipid acyltransferase (CoA-dependent) D 2.3.1.149 platelet-activating factor acetyltransferase D 2.3.1.150 salutaridinol 7-O-acetyltransferase D 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase D 2.3.1.152 alcohol O-cinnamoyltransferase D 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase) D 2.3.1.154 propionyl-CoA C2-trimethyltridecanoyltransferase D 2.3.1.155 acetyl-CoA C-myristoyltransferase D 2.3.1.156 phloroisovalerophenone synthase D 2.3.1.157 glucosamine-1-phosphate N-acetyltransferase D 2.3.1.158 phospholipid:diacylglycerol acyltransferase D 2.3.1.159 acridone synthase D 2.3.1.160 vinorine synthase D 2.3.1.161 lovastatin nonaketide synthase D 2.3.1.162 taxadien-5alpha-ol O-acetyltransferase D 2.3.1.163 10-hydroxytaxane O-acetyltransferase D 2.3.1.164 isopenicillin-N N-acyltransferase D 2.3.1.165 6-methylsalicylic-acid synthase D 2.3.1.166 2alpha-hydroxytaxane 2-O-benzoyltransferase D 2.3.1.167 10-deacetylbaccatin III 10-O-acetyltransferase D 2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase D 2.3.1.169 CO-methylating acetyl-CoA synthase D 2.3.1.170 6'-deoxychalcone synthase D 2.3.1.171 anthocyanin 6''-O-malonyltransferase D 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase D 2.3.1.173 flavonol-3-O-triglucoside O-coumaroyltransferase D 2.3.1.174 3-oxoadipyl-CoA thiolase D 2.3.1.175 deacetylcephalosporin-C acetyltransferase D 2.3.1.176 propanoyl-CoA C-acyltransferase D 2.3.1.177 3,5-dihydroxybiphenyl synthase D 2.3.1.178 diaminobutyrate acetyltransferase D 2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II E PRU_2561 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D 2.3.1.180 beta-ketoacyl-[acyl-carrier-protein] synthase III E PRU_2938 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D 2.3.1.181 lipoyl(octanoyl) transferase D 2.3.1.182 (R)-citramalate synthase E PRU_0732 (R)-citramalate synthase K09011 cimA; D-citramalate synthase [EC:2.3.1.182] D 2.3.1.183 phosphinothricin acetyltransferase D 2.3.1.184 acyl-homoserine-lactone synthase D 2.3.1.185 tropine acyltransferase D 2.3.1.186 pseudotropine acyltransferase D 2.3.1.187 acetyl-S-ACP:malonate ACP transferase D 2.3.1.188 omega-hydroxypalmitate O-feruloyl transferase D 2.3.1.189 mycothiol synthase D 2.3.1.190 acetoin dehydrogenase D 2.3.1.191 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase E PRU_0708 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D 2.3.1.192 glycine N-phenylacetyltransferase D 2.3.1.193 tRNAMet cytidine acetyltransferase D 2.3.1.194 acetoacetyl-CoA synthase D 2.3.1.195 (Z)-3-hexen-1-ol acetyltransferase D 2.3.1.196 benzyl alcohol O-benzoyltransferase D 2.3.1.197 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase D 2.3.1.198 glycerol-3-phosphate 2-O-acyltransferase D 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase D 2.3.1.200 lipoyl amidotransferase D 2.3.1.201 UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase D 2.3.1.202 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase D 2.3.1.203 UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine N-acetyltransferase D 2.3.1.204 octanoyl-[GcvH]:protein N-octanoyltransferase D 2.3.1.205 fumigaclavine B O-acetyltransferase D 2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase D 2.3.1.207 beta-ketodecanoyl-[acyl-carrier-protein] synthase D 2.3.1.208 4-hydroxycoumarin synthase D 2.3.1.209 dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase D 2.3.1.210 dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase D 2.3.1.211 bisdemethoxycurcumin synthase D 2.3.1.212 benzalacetone synthase D 2.3.1.213 cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) 6'''-O-hydroxycinnamoyltransferase D 2.3.1.214 pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase D 2.3.1.215 anthocyanidin 3-O-glucoside 6''-O-acyltransferase D 2.3.1.216 5,7-dihydroxy-2-methylchromone synthase D 2.3.1.217 curcumin synthase D 2.3.1.218 phenylpropanoylacetyl-CoA synthase D 2.3.1.219 demethoxycurcumin synthase D 2.3.1.220 2,4,6-trihydroxybenzophenone synthase D 2.3.1.221 noranthrone synthase D 2.3.1.222 phosphate propanoyltransferase D 2.3.1.- E PRU_2910 lipid A biosynthesis acyltransferase K02517 htrB; lipid A biosynthesis lauroyl acyltransferase [EC:2.3.1.-] C 2.3.2 Aminoacyltransferases D 2.3.2.1 D-glutamyltransferase D 2.3.2.2 gamma-glutamyltransferase D 2.3.2.3 lysyltransferase D 2.3.2.4 gamma-glutamylcyclotransferase D 2.3.2.5 glutaminyl-peptide cyclotransferase D 2.3.2.6 leucyltransferase E PRU_0039 aat; leucyltransferase K00684 aat; leucyl/phenylalanyl-tRNA--protein transferase [EC:2.3.2.6] D 2.3.2.7 aspartyltransferase D 2.3.2.8 arginyltransferase D 2.3.2.9 agaritine gamma-glutamyltransferase D 2.3.2.10 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase D 2.3.2.11 alanylphosphatidylglycerol synthase D 2.3.2.12 peptidyltransferase D 2.3.2.13 protein-glutamine gamma-glutamyltransferase D 2.3.2.14 D-alanine gamma-glutamyltransferase D 2.3.2.15 glutathione gamma-glutamylcysteinyltransferase D 2.3.2.16 lipid II:glycine glycyltransferase D 2.3.2.17 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase D 2.3.2.18 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase D 2.3.2.19 ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase D 2.3.2.- C 2.3.3 Acyl groups converted into alkyl groups on transfer D 2.3.3.1 citrate (Si)-synthase D 2.3.3.2 decylcitrate synthase D 2.3.3.3 citrate (Re)-synthase D 2.3.3.4 decylhomocitrate synthase D 2.3.3.5 2-methylcitrate synthase D 2.3.3.6 2-ethylmalate synthase D 2.3.3.7 3-ethylmalate synthase D 2.3.3.8 ATP citrate synthase D 2.3.3.9 malate synthase D 2.3.3.10 hydroxymethylglutaryl-CoA synthase D 2.3.3.11 2-hydroxyglutarate synthase D 2.3.3.12 3-propylmalate synthase D 2.3.3.13 2-isopropylmalate synthase E PRU_0729 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D 2.3.3.14 homocitrate synthase D 2.3.3.15 sulfoacetaldehyde acetyltransferase D 2.3.3.- C 2.3.- Acyltransferases D 2.3.-.- B 2.4 Glycosyltransferases C 2.4.1 Hexosyltransferases D 2.4.1.1 phosphorylase E PRU_0671 malP; maltodextrin phosphorylase K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1] D 2.4.1.2 dextrin dextranase D 2.4.1.4 amylosucrase D 2.4.1.5 dextransucrase D 2.4.1.7 sucrose phosphorylase D 2.4.1.8 maltose phosphorylase D 2.4.1.9 inulosucrase D 2.4.1.10 levansucrase D 2.4.1.11 glycogen(starch) synthase D 2.4.1.12 cellulose synthase (UDP-forming) D 2.4.1.13 sucrose synthase D 2.4.1.14 sucrose-phosphate synthase D 2.4.1.15 alpha,alpha-trehalose-phosphate synthase (UDP-forming) D 2.4.1.16 chitin synthase D 2.4.1.17 glucuronosyltransferase D 2.4.1.18 1,4-alpha-glucan branching enzyme E PRU_1305 1 K00700 glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D 2.4.1.19 cyclomaltodextrin glucanotransferase D 2.4.1.20 cellobiose phosphorylase D 2.4.1.21 starch synthase (glycosyl-transferring) E PRU_0992 glycogen synthase-like protein K00703 E2.4.1.21; starch synthase [EC:2.4.1.21] D 2.4.1.22 lactose synthase D 2.4.1.23 sphingosine beta-galactosyltransferase D 2.4.1.24 1,4-alpha-glucan 6-alpha-glucosyltransferase D 2.4.1.25 4-alpha-glucanotransferase E PRU_2751 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D 2.4.1.26 DNA alpha-glucosyltransferase D 2.4.1.27 DNA beta-glucosyltransferase D 2.4.1.28 glucosyl-DNA beta-glucosyltransferase D 2.4.1.29 cellulose synthase (GDP-forming) D 2.4.1.30 1,3-beta-oligoglucan phosphorylase D 2.4.1.31 laminaribiose phosphorylase D 2.4.1.32 glucomannan 4-beta-mannosyltransferase D 2.4.1.33 alginate synthase D 2.4.1.34 1,3-beta-glucan synthase D 2.4.1.35 phenol beta-glucosyltransferase D 2.4.1.36 alpha,alpha-trehalose-phosphate synthase (GDP-forming) D 2.4.1.37 fucosylgalactoside 3-alpha-galactosyltransferase D 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase D 2.4.1.39 steroid N-acetylglucosaminyltransferase D 2.4.1.40 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase D 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase D 2.4.1.43 polygalacturonate 4-alpha-galacturonosyltransferase D 2.4.1.44 lipopolysaccharide 3-alpha-galactosyltransferase D 2.4.1.45 2-hydroxyacylsphingosine 1-beta-galactosyltransferase D 2.4.1.46 monogalactosyldiacylglycerol synthase D 2.4.1.47 N-acylsphingosine galactosyltransferase D 2.4.1.48 heteroglycan alpha-mannosyltransferase D 2.4.1.49 cellodextrin phosphorylase D 2.4.1.50 procollagen galactosyltransferase D 2.4.1.52 poly(glycerol-phosphate) alpha-glucosyltransferase D 2.4.1.53 poly(ribitol-phosphate) beta-glucosyltransferase D 2.4.1.54 undecaprenyl-phosphate mannosyltransferase D 2.4.1.56 lipopolysaccharide N-acetylglucosaminyltransferase D 2.4.1.57 phosphatidylinositol alpha-mannosyltransferase D 2.4.1.58 lipopolysaccharide glucosyltransferase I D 2.4.1.60 abequosyltransferase D 2.4.1.62 ganglioside galactosyltransferase D 2.4.1.63 linamarin synthase D 2.4.1.64 alpha,alpha-trehalose phosphorylase D 2.4.1.65 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase D 2.4.1.66 procollagen glucosyltransferase D 2.4.1.67 galactinol---raffinose galactosyltransferase D 2.4.1.68 glycoprotein 6-alpha-L-fucosyltransferase D 2.4.1.69 galactoside 2-alpha-L-fucosyltransferase D 2.4.1.70 poly(ribitol-phosphate) N-acetylglucosaminyltransferase D 2.4.1.71 arylamine glucosyltransferase D 2.4.1.73 lipopolysaccharide glucosyltransferase II D 2.4.1.74 glycosaminoglycan galactosyltransferase D 2.4.1.78 phosphopolyprenol glucosyltransferase D 2.4.1.79 globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase D 2.4.1.80 ceramide glucosyltransferase D 2.4.1.81 flavone 7-O-beta-glucosyltransferase D 2.4.1.82 galactinol---sucrose galactosyltransferase D 2.4.1.83 dolichyl-phosphate beta-D-mannosyltransferase E PRU_1610 group 2 family glycosyltransferase K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83] D 2.4.1.85 cyanohydrin beta-glucosyltransferase D 2.4.1.86 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase D 2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase D 2.4.1.88 globoside alpha-N-acetylgalactosaminyltransferase D 2.4.1.90 N-acetyllactosamine synthase D 2.4.1.91 flavonol 3-O-glucosyltransferase D 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase D 2.4.1.94 protein N-acetylglucosaminyltransferase D 2.4.1.95 bilirubin-glucuronoside glucuronosyltransferase D 2.4.1.96 sn-glycerol-3-phosphate 1-galactosyltransferase D 2.4.1.97 1,3-beta-D-glucan phosphorylase D 2.4.1.99 sucrose:sucrose fructosyltransferase D 2.4.1.100 2,1-fructan:2,1-fructan 1-fructosyltransferase D 2.4.1.101 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase D 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.103 alizarin 2-beta-glucosyltransferase D 2.4.1.104 o-dihydroxycoumarin 7-O-glucosyltransferase D 2.4.1.105 vitexin beta-glucosyltransferase D 2.4.1.106 isovitexin beta-glucosyltransferase D 2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase D 2.4.1.110 tRNA-queuosine beta-mannosyltransferase D 2.4.1.111 coniferyl-alcohol glucosyltransferase D 2.4.1.113 alpha-1,4-glucan-protein synthase (ADP-forming) D 2.4.1.114 2-coumarate O-beta-glucosyltransferase D 2.4.1.115 anthocyanidin 3-O-glucosyltransferase D 2.4.1.116 cyanidin 3-O-rutinoside 5-O-glucosyltransferase D 2.4.1.117 dolichyl-phosphate beta-glucosyltransferase D 2.4.1.118 cytokinin 7-beta-glucosyltransferase D 2.4.1.120 sinapate 1-glucosyltransferase D 2.4.1.121 indole-3-acetate beta-glucosyltransferase D 2.4.1.122 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase D 2.4.1.123 inositol 3-alpha-galactosyltransferase D 2.4.1.125 sucrose---1,6-alpha-glucan 3(6)-alpha-glucosyltransferase D 2.4.1.126 hydroxycinnamate 4-beta-glucosyltransferase D 2.4.1.127 monoterpenol beta-glucosyltransferase D 2.4.1.128 scopoletin glucosyltransferase D 2.4.1.129 peptidoglycan glycosyltransferase E PRU_2327 pbpB; penicillin-binding protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:2.4.1.129] D 2.4.1.131 GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.132 GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase D 2.4.1.133 xylosylprotein 4-beta-galactosyltransferase D 2.4.1.134 galactosylxylosylprotein 3-beta-galactosyltransferase D 2.4.1.135 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase D 2.4.1.136 gallate 1-beta-glucosyltransferase D 2.4.1.137 sn-glycerol-3-phosphate 2-alpha-galactosyltransferase D 2.4.1.138 mannotetraose 2-alpha-N-acetylglucosaminyltransferase D 2.4.1.139 maltose synthase D 2.4.1.140 alternansucrase D 2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase D 2.4.1.142 chitobiosyldiphosphodolichol beta-mannosyltransferase D 2.4.1.143 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase D 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.145 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.146 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.147 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.149 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase D 2.4.1.152 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase D 2.4.1.153 dolichyl-phosphate alpha-N-acetylglucosaminyltransferase D 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase D 2.4.1.156 indolylacetyl-myo-inositol galactosyltransferase D 2.4.1.157 1,2-diacylglycerol 3-glucosyltransferase D 2.4.1.158 13-hydroxydocosanoate 13-beta-glucosyltransferase D 2.4.1.159 flavonol-3-O-glucoside L-rhamnosyltransferase D 2.4.1.160 pyridoxine 5'-O-beta-D-glucosyltransferase D 2.4.1.161 oligosaccharide 4-alpha-D-glucosyltransferase D 2.4.1.162 aldose beta-D-fructosyltransferase D 2.4.1.163 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase D 2.4.1.164 galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.165 N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase D 2.4.1.166 raffinose---raffinose alpha-galactosyltransferase D 2.4.1.167 sucrose 6F-alpha-galactosyltransferase D 2.4.1.168 xyloglucan 4-glucosyltransferase D 2.4.1.170 isoflavone 7-O-glucosyltransferase D 2.4.1.171 methyl-ONN-azoxymethanol beta-D-glucosyltransferase D 2.4.1.172 salicyl-alcohol beta-D-glucosyltransferase D 2.4.1.173 sterol 3beta-glucosyltransferase D 2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.176 gibberellin beta-D-glucosyltransferase D 2.4.1.177 cinnamate beta-D-glucosyltransferase D 2.4.1.178 hydroxymandelonitrile glucosyltransferase D 2.4.1.179 lactosylceramide beta-1,3-galactosyltransferase D 2.4.1.180 lipopolysaccharide N-acetylmannosaminouronosyltransferase D 2.4.1.181 hydroxyanthraquinone glucosyltransferase D 2.4.1.182 lipid-A-disaccharide synthase E PRU_0019 lpxB; lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D 2.4.1.183 alpha-1,3-glucan synthase D 2.4.1.184 galactolipid galactosyltransferase D 2.4.1.185 flavanone 7-O-beta-glucosyltransferase D 2.4.1.186 glycogenin glucosyltransferase D 2.4.1.187 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase D 2.4.1.188 N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase D 2.4.1.189 luteolin 7-O-glucuronosyltransferase D 2.4.1.190 luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase D 2.4.1.191 luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase D 2.4.1.192 nuatigenin 3beta-glucosyltransferase D 2.4.1.193 sarsapogenin 3beta-glucosyltransferase D 2.4.1.194 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase D 2.4.1.195 N-hydroxythioamide S-beta-glucosyltransferase D 2.4.1.196 nicotinate glucosyltransferase D 2.4.1.197 high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase D 2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase D 2.4.1.199 beta-mannosylphosphodecaprenol---mannooligosaccharide 6-mannosyltransferase D 2.4.1.201 alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.202 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase D 2.4.1.203 trans-zeatin O-beta-D-glucosyltransferase D 2.4.1.205 galactogen 6beta-galactosyltransferase D 2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase D 2.4.1.207 xyloglucan:xyloglucosyl transferase D 2.4.1.208 diglucosyl diacylglycerol synthase D 2.4.1.209 cis-p-coumarate glucosyltransferase D 2.4.1.210 limonoid glucosyltransferase D 2.4.1.211 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase D 2.4.1.212 hyaluronan synthase D 2.4.1.213 glucosylglycerol-phosphate synthase D 2.4.1.214 glycoprotein 3-alpha-L-fucosyltransferase D 2.4.1.215 cis-zeatin O-beta-D-glucosyltransferase D 2.4.1.216 trehalose 6-phosphate phosphorylase D 2.4.1.217 mannosyl-3-phosphoglycerate synthase D 2.4.1.218 hydroquinone glucosyltransferase D 2.4.1.219 vomilenine glucosyltransferase D 2.4.1.220 indoxyl-UDPG glucosyltransferase D 2.4.1.221 peptide-O-fucosyltransferase D 2.4.1.222 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase D 2.4.1.223 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase D 2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase D 2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase D 2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase D 2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase E PRU_2332 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D 2.4.1.228 lactosylceramide 4-alpha-galactosyltransferase D 2.4.1.229 [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase D 2.4.1.230 kojibiose phosphorylase D 2.4.1.231 alpha,alpha-trehalose phosphorylase (configuration-retaining) D 2.4.1.232 initiation-specific alpha-1,6-mannosyltransferase D 2.4.1.234 kaempferol 3-O-galactosyltransferase D 2.4.1.236 flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase D 2.4.1.237 flavonol 7-O-beta-glucosyltransferase D 2.4.1.238 delphinidin 3,5-di-O-glucoside 3'-O-glucosyltransferase D 2.4.1.239 flavonol-3-O-glucoside glucosyltransferase D 2.4.1.240 flavonol-3-O-glycoside glucosyltransferase D 2.4.1.241 digalactosyldiacylglycerol synthase D 2.4.1.242 NDP-glucose---starch glucosyltransferase D 2.4.1.243 6G-fructosyltransferase D 2.4.1.244 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.245 alpha,alpha-trehalose synthase D 2.4.1.246 mannosylfructose-phosphate synthase D 2.4.1.247 beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase D 2.4.1.248 cycloisomaltooligosaccharide glucanotransferase D 2.4.1.249 delphinidin 3',5'-O-glucosyltransferase D 2.4.1.250 D-inositol-3-phosphate glycosyltransferase D 2.4.1.251 GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase D 2.4.1.252 GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase D 2.4.1.253 baicalein 7-O-glucuronosyltransferase D 2.4.1.254 cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase D 2.4.1.255 protein O-GlcNAc transferase D 2.4.1.256 dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase D 2.4.1.257 GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase D 2.4.1.258 dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase D 2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.260 dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase D 2.4.1.261 dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.262 soyasapogenol glucuronosyltransferase D 2.4.1.263 abscisate beta-glucosyltransferase D 2.4.1.264 D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronyltransferase D 2.4.1.265 dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase D 2.4.1.266 glucosyl-3-phosphoglycerate synthase D 2.4.1.267 dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase D 2.4.1.268 glucosylglycerate synthase D 2.4.1.269 mannosylglycerate synthase D 2.4.1.270 mannosylglucosyl-3-phosphoglycerate synthase D 2.4.1.271 crocetin glucosyltransferase D 2.4.1.272 soyasapogenol B glucuronide galactosyltransferase D 2.4.1.273 soyasaponin III rhamnosyltransferase D 2.4.1.274 glucosylceramide beta-1,4-galactosyltransferase D 2.4.1.275 neolactotriaosylceramide beta-1,4-galactosyltransferase D 2.4.1.276 zeaxanthin glucosyltransferase D 2.4.1.277 glycosyltransferase DesVII D 2.4.1.278 desosaminyl transferase EryCIII D 2.4.1.279 nigerose phosphorylase D 2.4.1.280 N,N'-diacetylchitobiose phosphorylase D 2.4.1.281 4-O-beta-D-mannosyl-D-glucose phosphorylase E PRU_1725 hypothetical protein K16212 mgp; 4-O-beta-D-mannosyl-D-glucose phosphorylase [EC:2.4.1.281] D 2.4.1.282 3-O-alpha-D-glucosyl-L-rhamnose phosphorylase D 2.4.1.283 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase D 2.4.1.284 2-deoxystreptamine glucosyltransferase D 2.4.1.285 UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase D 2.4.1.286 chalcone 4'-O-glucosyltransferase D 2.4.1.287 rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,3/1,4-galactofuranosyltransferase D 2.4.1.288 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase D 2.4.1.289 N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase D 2.4.1.290 N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase D 2.4.1.291 N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase D 2.4.1.292 GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase D 2.4.1.293 GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase D 2.4.1.294 cyanidin 3-O-galactosyltransferase D 2.4.1.295 anthocyanin 3-O-sambubioside 5-O-glucosyltransferase D 2.4.1.296 anthocyanidin 3-O-coumaroylrutinoside 5-O-glucosyltransferase D 2.4.1.297 anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase D 2.4.1.298 anthocyanidin 3-O-glucoside 5-O-glucosyltransferase D 2.4.1.299 cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose) D 2.4.1.300 cyanidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose) D 2.4.1.- E PRU_1042 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase [EC:2.4.1.-] E PRU_0638 penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.1.- 3.4.-.-] E PRU_0704 penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.1.- 3.4.-.-] C 2.4.2 Pentosyltransferases D 2.4.2.1 purine-nucleoside phosphorylase E PRU_0310 punA; purine nucleoside phosphorylase I, inosine and guanosine-specific K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] D 2.4.2.2 pyrimidine-nucleoside phosphorylase D 2.4.2.3 uridine phosphorylase E PRU_0696 phosphorylase family protein K00757 E2.4.2.3; uridine phosphorylase [EC:2.4.2.3] D 2.4.2.4 thymidine phosphorylase D 2.4.2.5 nucleoside ribosyltransferase D 2.4.2.6 nucleoside deoxyribosyltransferase D 2.4.2.7 adenine phosphoribosyltransferase E PRU_2478 adenine phosphoribosyltransferase K00759 E2.4.2.7; adenine phosphoribosyltransferase [EC:2.4.2.7] D 2.4.2.8 hypoxanthine phosphoribosyltransferase E PRU_2868 hpt; hypoxanthine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D 2.4.2.9 uracil phosphoribosyltransferase E PRU_2270 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D 2.4.2.10 orotate phosphoribosyltransferase E PRU_2395 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D 2.4.2.11 nicotinate phosphoribosyltransferase D 2.4.2.12 nicotinamide phosphoribosyltransferase D 2.4.2.14 amidophosphoribosyltransferase E PRU_1973 glutamine amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] E PRU_0553 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D 2.4.2.15 guanosine phosphorylase D 2.4.2.16 urate-ribonucleotide phosphorylase D 2.4.2.17 ATP phosphoribosyltransferase E PRU_0390 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D 2.4.2.18 anthranilate phosphoribosyltransferase E PRU_1457 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D 2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating) E PRU_0740 nadC; nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D 2.4.2.20 dioxotetrahydropyrimidine phosphoribosyltransferase D 2.4.2.21 nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase E PRU_1094 cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase K00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21] D 2.4.2.22 xanthine phosphoribosyltransferase E PRU_0581 xpt; xanthine phosphoribosyltransferase K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D 2.4.2.23 deoxyuridine phosphorylase D 2.4.2.24 1,4-beta-D-xylan synthase D 2.4.2.25 flavone apiosyltransferase D 2.4.2.26 protein xylosyltransferase D 2.4.2.27 dTDP-dihydrostreptose---streptidine-6-phosphate dihydrostreptosyltransferase D 2.4.2.28 S-methyl-5'-thioadenosine phosphorylase D 2.4.2.29 tRNA-guanosine34 transglycosylase E PRU_0843 tgt; tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D 2.4.2.30 NAD+ ADP-ribosyltransferase D 2.4.2.31 NAD+---protein-arginine ADP-ribosyltransferase D 2.4.2.32 dolichyl-phosphate D-xylosyltransferase D 2.4.2.33 dolichyl-xylosyl-phosphate---protein xylosyltransferase D 2.4.2.34 indolylacetylinositol arabinosyltransferase D 2.4.2.35 flavonol-3-O-glycoside xylosyltransferase D 2.4.2.36 NAD+---diphthamide ADP-ribosyltransferase D 2.4.2.37 NAD+---dinitrogen-reductase ADP-D-ribosyltransferase D 2.4.2.38 glycoprotein 2-beta-D-xylosyltransferase D 2.4.2.39 xyloglucan 6-xylosyltransferase D 2.4.2.40 zeatin O-beta-D-xylosyltransferase D 2.4.2.41 xylogalacturonan beta-1,3-xylosyltransferase D 2.4.2.42 UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase D 2.4.2.43 lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase D 2.4.2.44 S-methyl-5'-thioinosine phosphorylase D 2.4.2.45 decaprenyl-phosphate phosphoribosyltransferase D 2.4.2.46 galactan 5-O-arabinofuranosyltransferase D 2.4.2.47 arabinofuranan 3-O-arabinosyltransferase D 2.4.2.48 tRNA-guanine15 transglycosylase D 2.4.2.49 neamine phosphoribosyltransferase D 2.4.2.50 cyanidin 3-O-galactoside 2''-O-xylosyltransferase D 2.4.2.51 anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase D 2.4.2.- E PRU_0485 hisH; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; glutamine amidotransferase [EC:2.4.2.-] C 2.4.99 Transferring other glycosyl groups D 2.4.99.1 beta-galactoside alpha-2,6-sialyltransferase D 2.4.99.2 monosialoganglioside sialyltransferase D 2.4.99.3 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase D 2.4.99.4 beta-galactoside alpha-2,3-sialyltransferase D 2.4.99.5 galactosyldiacylglycerol alpha-2,3-sialyltransferase D 2.4.99.6 N-acetyllactosaminide alpha-2,3-sialyltransferase D 2.4.99.7 alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide 6-alpha-sialyltransferase D 2.4.99.8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase D 2.4.99.9 lactosylceramide alpha-2,3-sialyltransferase D 2.4.99.10 neolactotetraosylceramide alpha-2,3-sialyltransferase D 2.4.99.11 lactosylceramide alpha-2,6-N-sialyltransferase D 2.4.99.12 lipid IVA 3-deoxy-D-manno-octulosonic acid transferase E PRU_2166 glycosyl transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.13 (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase E PRU_2166 glycosyl transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.14 (KDO)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase E PRU_2166 glycosyl transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.15 (KDO)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase E PRU_2166 glycosyl transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.16 starch synthase (maltosyl-transferring) D 2.4.99.17 S-adenosylmethionine:tRNA ribosyltransferase-isomerase E PRU_1831 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] E PRU_0763 S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D 2.4.99.18 dolichyl-diphosphooligosaccharide---protein glycotransferase D 2.4.99.19 undecaprenyl-diphosphooligosaccharide---protein glycotransferase D 2.4.99.- C 2.4.- Glycosyltransferases D 2.4.-.- B 2.5 Transferring alkyl or aryl groups, other than methyl groups C 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) D 2.5.1.1 dimethylallyltranstransferase E PRU_1825 idsA; short chain isoprenyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D 2.5.1.2 thiamine pyridinylase D 2.5.1.3 thiamine-phosphate diphosphorylase E PRU_0400 thiE; thiamine-phosphate diphosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] E PRU_0405 thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D 2.5.1.4 adenosylmethionine cyclotransferase D 2.5.1.5 galactose-6-sulfurylase D 2.5.1.6 methionine adenosyltransferase E PRU_2294 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D 2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase E PRU_2927 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D 2.5.1.9 riboflavin synthase E PRU_1369 ribE; riboflavin synthase subunit alpha K00793 ribE; riboflavin synthase [EC:2.5.1.9] D 2.5.1.10 (2E,6E)-farnesyl diphosphate synthase E PRU_1825 idsA; short chain isoprenyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D 2.5.1.15 dihydropteroate synthase E PRU_2262 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D 2.5.1.16 spermidine synthase D 2.5.1.17 cob(I)yrinic acid a,c-diamide adenosyltransferase D 2.5.1.18 glutathione transferase D 2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase E PRU_1902 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D 2.5.1.20 rubber cis-polyprenylcistransferase D 2.5.1.21 squalene synthase D 2.5.1.22 spermine synthase D 2.5.1.23 sym-norspermidine synthase D 2.5.1.24 discadenine synthase D 2.5.1.25 tRNA-uridine aminocarboxypropyltransferase D 2.5.1.26 alkylglycerone-phosphate synthase D 2.5.1.27 adenylate dimethylallyltransferase D 2.5.1.28 dimethylallylcistransferase D 2.5.1.29 geranylgeranyl diphosphate synthase E PRU_1825 idsA; short chain isoprenyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29] D 2.5.1.30 heptaprenyl diphosphate synthase D 2.5.1.31 ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] E PRU_2282 uppS; di-trans,poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D 2.5.1.32 15-cis-phytoene synthase D 2.5.1.34 4-dimethylallyltryptophan synthase D 2.5.1.35 aspulvinone dimethylallyltransferase D 2.5.1.36 trihydroxypterocarpan dimethylallyltransferase D 2.5.1.38 isonocardicin synthase D 2.5.1.39 4-hydroxybenzoate polyprenyltransferase D 2.5.1.41 phosphoglycerol geranylgeranyltransferase D 2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase D 2.5.1.43 nicotianamine synthase D 2.5.1.44 homospermidine synthase D 2.5.1.45 homospermidine synthase (spermidine-specific) D 2.5.1.46 deoxyhypusine synthase D 2.5.1.47 cysteine synthase E PRU_2792 cysK; cysteine synthase A K01738 cysK; cysteine synthase A [EC:2.5.1.47] D 2.5.1.48 cystathionine gamma-synthase D 2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase E PRU_2080 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein K01740 E2.5.1.49; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] E PRU_2791 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein K01740 E2.5.1.49; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D 2.5.1.50 zeatin 9-aminocarboxyethyltransferase D 2.5.1.51 beta-pyrazolylalanine synthase D 2.5.1.52 L-mimosine synthase D 2.5.1.53 uracilylalanine synthase D 2.5.1.54 3-deoxy-7-phosphoheptulonate synthase D 2.5.1.55 3-deoxy-8-phosphooctulonate synthase E PRU_1626 kdsA_2; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] E PRU_0445 kdsA_1; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D 2.5.1.56 N-acetylneuraminate synthase D 2.5.1.57 N-acylneuraminate-9-phosphate synthase D 2.5.1.58 protein farnesyltransferase D 2.5.1.59 protein geranylgeranyltransferase type I D 2.5.1.60 protein geranylgeranyltransferase type II D 2.5.1.61 hydroxymethylbilane synthase D 2.5.1.62 chlorophyll synthase D 2.5.1.63 adenosyl-fluoride synthase D 2.5.1.65 O-phosphoserine sulfhydrylase D 2.5.1.66 N2-(2-carboxyethyl)arginine synthase D 2.5.1.67 chrysanthemyl diphosphate synthase D 2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase D 2.5.1.69 lavandulyl diphosphate synthase D 2.5.1.70 naringenin 8-dimethylallyltransferase D 2.5.1.71 leachianone-G 2''-dimethylallyltransferase D 2.5.1.72 quinolinate synthase E PRU_2530 nadA; quinolinate synthetase complex subunit A K03517 nadA; quinolinate synthase [EC:2.5.1.72] D 2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase D 2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase E PRU_1360 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase [EC:2.5.1.74 2.5.1.-] D 2.5.1.75 tRNA dimethylallyltransferase E PRU_1663 miaA_2; tRNA isopentenyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] E PRU_0705 miaA_1; tRNA isopentenyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D 2.5.1.76 cysteate synthase D 2.5.1.77 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase D 2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase E PRU_0203 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D 2.5.1.79 thermospermine synthase D 2.5.1.80 7-dimethylallyltryptophan synthase D 2.5.1.81 geranylfarnesyl diphosphate synthase D 2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.83 hexaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] D 2.5.1.84 all-trans-nonaprenyl-diphosphate synthase [geranyl-diphosphate specific] D 2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.86 trans,polycis-decaprenyl diphosphate synthase D 2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] D 2.5.1.88 trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] D 2.5.1.89 tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.90 all-trans-octaprenyl-diphosphate synthase E PRU_2484 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D 2.5.1.91 all-trans-decaprenyl-diphosphate synthase D 2.5.1.92 (2Z,6Z)-farnesyl diphosphate synthase D 2.5.1.93 4-hydroxybenzoate geranyltransferase D 2.5.1.94 adenosyl-chloride synthase D 2.5.1.95 xanthan ketal pyruvate transferase D 2.5.1.96 4,4'-diapophytoene synthase D 2.5.1.97 pseudaminic acid synthase D 2.5.1.98 Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase D 2.5.1.99 all-trans-phytoene synthase D 2.5.1.100 fumigaclavine A dimethylallyltransferase D 2.5.1.101 N,N'-diacetyllegionaminate synthase D 2.5.1.102 geranyl-pyrophosphate---olivetolic acid geranyltransferase D 2.5.1.103 presqualene diphosphate synthase D 2.5.1.- E PRU_1360 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase [EC:2.5.1.74 2.5.1.-] B 2.6 Transferring nitrogenous groups C 2.6.1 Transaminases D 2.6.1.1 aspartate transaminase E PRU_1914 aatA; aspartate aminotransferase K00812 E2.6.1.1A; aspartate aminotransferase [EC:2.6.1.1] E PRU_1300 aspartate aminotransferase K00812 E2.6.1.1A; aspartate aminotransferase [EC:2.6.1.1] D 2.6.1.2 alanine transaminase D 2.6.1.3 cysteine transaminase D 2.6.1.4 glycine transaminase D 2.6.1.5 tyrosine transaminase D 2.6.1.6 leucine transaminase D 2.6.1.7 kynurenine---oxoglutarate transaminase D 2.6.1.8 2,5-diaminovalerate transaminase D 2.6.1.9 histidinol-phosphate transaminase E PRU_0388 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] E PRU_2906 class I/II aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D 2.6.1.11 acetylornithine transaminase E PRU_2201 argD; acetylornithine transaminase K00818 E2.6.1.11; acetylornithine aminotransferase [EC:2.6.1.11] D 2.6.1.12 alanine---oxo-acid transaminase D 2.6.1.13 ornithine aminotransferase D 2.6.1.14 asparagine---oxo-acid transaminase D 2.6.1.15 glutamine---pyruvate transaminase D 2.6.1.16 glutamine---fructose-6-phosphate transaminase (isomerizing) E PRU_0891 glmS; glutamine--fructose-6-phosphate transaminase K00820 E2.6.1.16; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] D 2.6.1.17 succinyldiaminopimelate transaminase D 2.6.1.18 beta-alanine---pyruvate transaminase D 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase D 2.6.1.21 D-amino-acid transaminase D 2.6.1.22 (S)-3-amino-2-methylpropionate transaminase D 2.6.1.23 4-hydroxyglutamate transaminase D 2.6.1.24 diiodotyrosine transaminase D 2.6.1.26 thyroid-hormone transaminase D 2.6.1.27 tryptophan transaminase D 2.6.1.28 tryptophan---phenylpyruvate transaminase D 2.6.1.29 diamine transaminase D 2.6.1.30 pyridoxamine---pyruvate transaminase D 2.6.1.31 pyridoxamine---oxaloacetate transaminase D 2.6.1.32 valine---3-methyl-2-oxovalerate transaminase D 2.6.1.33 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase D 2.6.1.34 UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase D 2.6.1.35 glycine---oxaloacetate transaminase D 2.6.1.36 L-lysine 6-transaminase D 2.6.1.37 2-aminoethylphosphonate---pyruvate transaminase D 2.6.1.38 histidine transaminase D 2.6.1.39 2-aminoadipate transaminase D 2.6.1.40 (R)-3-amino-2-methylpropionate---pyruvate transaminase D 2.6.1.41 D-methionine---pyruvate transaminase D 2.6.1.42 branched-chain-amino-acid transaminase E PRU_0166 ilvE; branched-chain-amino-acid transaminase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D 2.6.1.43 aminolevulinate transaminase D 2.6.1.44 alanine---glyoxylate transaminase D 2.6.1.45 serine---glyoxylate transaminase D 2.6.1.46 diaminobutyrate---pyruvate transaminase D 2.6.1.47 alanine---oxomalonate transaminase D 2.6.1.48 5-aminovalerate transaminase D 2.6.1.49 dihydroxyphenylalanine transaminase D 2.6.1.50 glutamine---scyllo-inositol transaminase D 2.6.1.51 serine---pyruvate transaminase D 2.6.1.52 phosphoserine transaminase E PRU_1038 serC; phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D 2.6.1.54 pyridoxamine-phosphate transaminase D 2.6.1.55 taurine---2-oxoglutarate transaminase D 2.6.1.56 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase D 2.6.1.57 aromatic-amino-acid transaminase D 2.6.1.58 phenylalanine(histidine) transaminase D 2.6.1.59 dTDP-4-amino-4,6-dideoxygalactose transaminase D 2.6.1.60 aromatic-amino-acid---glyoxylate transaminase D 2.6.1.62 adenosylmethionine---8-amino-7-oxononanoate transaminase D 2.6.1.63 kynurenine---glyoxylate transaminase D 2.6.1.64 glutamine---phenylpyruvate transaminase D 2.6.1.65 N6-acetyl-beta-lysine transaminase D 2.6.1.66 valine---pyruvate transaminase D 2.6.1.67 2-aminohexanoate transaminase D 2.6.1.68 ornithine(lysine) transaminase D 2.6.1.70 aspartate---phenylpyruvate transaminase D 2.6.1.71 lysine---pyruvate 6-transaminase D 2.6.1.72 D-4-hydroxyphenylglycine transaminase D 2.6.1.73 methionine---glyoxylate transaminase D 2.6.1.74 cephalosporin-C transaminase D 2.6.1.75 cysteine-conjugate transaminase D 2.6.1.76 diaminobutyrate---2-oxoglutarate transaminase D 2.6.1.77 taurine---pyruvate aminotransferase D 2.6.1.78 aspartate---prephenate aminotransferase D 2.6.1.79 glutamate---prephenate aminotransferase D 2.6.1.80 nicotianamine aminotransferase D 2.6.1.81 succinylornithine transaminase D 2.6.1.82 putrescine aminotransferase D 2.6.1.83 LL-diaminopimelate aminotransferase E PRU_1974 aminotransferase-like protein K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] D 2.6.1.84 arginine---pyruvate transaminase D 2.6.1.85 aminodeoxychorismate synthase D 2.6.1.86 2-amino-4-deoxychorismate synthase D 2.6.1.87 UDP-4-amino-4-deoxy-L-arabinose aminotransferase D 2.6.1.88 methionine transaminase D 2.6.1.89 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase D 2.6.1.90 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase D 2.6.1.91 UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine transaminase D 2.6.1.92 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase D 2.6.1.93 neamine transaminase D 2.6.1.94 2'-deamino-2'-hydroxyneamine transaminase D 2.6.1.95 neomycin C transaminase D 2.6.1.96 4-aminobutyrate---pyruvate transaminase D 2.6.1.97 archaeosine synthase D 2.6.1.98 UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase D 2.6.1.99 L-tryptophan---pyruvate aminotransferase D 2.6.1.100 L-glutamine:2-deoxy-scyllo-inosose aminotransferase D 2.6.1.101 L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase D 2.6.1.- C 2.6.3 Oximinotransferases D 2.6.3.1 oximinotransferase C 2.6.99 Transferring other nitrogenous groups D 2.6.99.1 dATP(dGTP)---DNA purinetransferase D 2.6.99.2 pyridoxine 5'-phosphate synthase C 2.6.- Transferring nitrogenous groups D 2.6.-.- E PRU_2768 pdxT; pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 K08681 pdxT; glutamine amidotransferase [EC:2.6.-.-] B 2.7 Transferring phosphorus-containing groups C 2.7.1 Phosphotransferases with an alcohol group as acceptor D 2.7.1.1 hexokinase D 2.7.1.2 glucokinase E PRU_0395 ROK family protein K00845 glk; glucokinase [EC:2.7.1.2] E PRU_0241 glkA; glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D 2.7.1.3 ketohexokinase D 2.7.1.4 fructokinase E PRU_2278 fructokinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] E PRU_2638 pfkB family kinase K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D 2.7.1.5 rhamnulokinase E PRU_1468 rhaB; rhamnulokinase K00848 rhaB; rhamnulokinase [EC:2.7.1.5] D 2.7.1.6 galactokinase E PRU_1544 galactokinase K00849 galK; galactokinase [EC:2.7.1.6] E PRU_0425 galK; galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D 2.7.1.7 mannokinase D 2.7.1.8 glucosamine kinase D 2.7.1.10 phosphoglucokinase D 2.7.1.11 6-phosphofructokinase E PRU_1201 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D 2.7.1.12 gluconokinase D 2.7.1.13 dehydrogluconokinase D 2.7.1.14 sedoheptulokinase D 2.7.1.15 ribokinase D 2.7.1.16 ribulokinase D 2.7.1.17 xylulokinase E PRU_1379 xylulokinase K00854 xylB; xylulokinase [EC:2.7.1.17] D 2.7.1.18 phosphoribokinase D 2.7.1.19 phosphoribulokinase D 2.7.1.20 adenosine kinase D 2.7.1.21 thymidine kinase E PRU_1868 tdk; thymidine kinase K00857 E2.7.1.21; thymidine kinase [EC:2.7.1.21] D 2.7.1.22 ribosylnicotinamide kinase D 2.7.1.23 NAD+ kinase E PRU_1941 ppnK; ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D 2.7.1.24 dephospho-CoA kinase E PRU_0244 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D 2.7.1.25 adenylyl-sulfate kinase D 2.7.1.26 riboflavin kinase E PRU_2617 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D 2.7.1.27 erythritol kinase D 2.7.1.28 triokinase D 2.7.1.29 glycerone kinase D 2.7.1.30 glycerol kinase D 2.7.1.31 glycerate 3-kinase E PRU_1696 glycerate kinase family protein K00865 glxK; glycerate kinase [EC:2.7.1.31] D 2.7.1.32 choline kinase D 2.7.1.33 pantothenate kinase E PRU_2454 transcriptional activator K03525 coaX; type III pantothenate kinase [EC:2.7.1.33] E PRU_0313 pantothenate kinase K09680 coaW; type II pantothenate kinase [EC:2.7.1.33] D 2.7.1.34 pantetheine kinase D 2.7.1.35 pyridoxal kinase E PRU_2660 pyridoxal kinase-like protein K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D 2.7.1.36 mevalonate kinase D 2.7.1.39 homoserine kinase D 2.7.1.40 pyruvate kinase E PRU_0684 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D 2.7.1.41 glucose-1-phosphate phosphodismutase D 2.7.1.42 riboflavin phosphotransferase D 2.7.1.43 glucuronokinase D 2.7.1.44 galacturonokinase D 2.7.1.45 2-dehydro-3-deoxygluconokinase E PRU_0873 2-dehydro-3-deoxygluconokinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D 2.7.1.46 L-arabinokinase D 2.7.1.47 D-ribulokinase D 2.7.1.48 uridine kinase E PRU_2603 phosphoribulokinase/uridine kinase family protein K00876 E2.7.1.48; uridine kinase [EC:2.7.1.48] E PRU_2486 phosphoribulokinase/uridine kinase family protein K00876 E2.7.1.48; uridine kinase [EC:2.7.1.48] E PRU_1343 udk; uridine kinase K00876 E2.7.1.48; uridine kinase [EC:2.7.1.48] D 2.7.1.49 hydroxymethylpyrimidine kinase E PRU_0406 thiD; phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D 2.7.1.50 hydroxyethylthiazole kinase D 2.7.1.51 L-fuculokinase D 2.7.1.52 fucokinase D 2.7.1.53 L-xylulokinase D 2.7.1.54 D-arabinokinase D 2.7.1.55 allose kinase D 2.7.1.56 1-phosphofructokinase D 2.7.1.58 2-dehydro-3-deoxygalactonokinase D 2.7.1.59 N-acetylglucosamine kinase D 2.7.1.60 N-acylmannosamine kinase D 2.7.1.61 acyl-phosphate---hexose phosphotransferase D 2.7.1.62 phosphoramidate---hexose phosphotransferase D 2.7.1.63 polyphosphate---glucose phosphotransferase D 2.7.1.64 inositol 3-kinase D 2.7.1.65 scyllo-inosamine 4-kinase D 2.7.1.66 undecaprenol kinase D 2.7.1.67 1-phosphatidylinositol 4-kinase D 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase D 2.7.1.69 protein-Npi-phosphohistidine---sugar phosphotransferase D 2.7.1.71 shikimate kinase E PRU_2626 aroK; shikimate kinase K00891 E2.7.1.71; shikimate kinase [EC:2.7.1.71] D 2.7.1.72 streptomycin 6-kinase D 2.7.1.73 inosine kinase D 2.7.1.74 deoxycytidine kinase D 2.7.1.76 2'-deoxyadenosine kinase D 2.7.1.77 nucleoside phosphotransferase D 2.7.1.78 polynucleotide 5'-hydroxyl-kinase D 2.7.1.79 diphosphate---glycerol phosphotransferase D 2.7.1.80 diphosphate---serine phosphotransferase D 2.7.1.81 hydroxylysine kinase D 2.7.1.82 ethanolamine kinase D 2.7.1.83 pseudouridine kinase D 2.7.1.84 alkylglycerone kinase D 2.7.1.85 beta-glucoside kinase D 2.7.1.86 NADH kinase D 2.7.1.87 streptomycin 3''-kinase D 2.7.1.88 dihydrostreptomycin-6-phosphate 3'alpha-kinase D 2.7.1.89 thiamine kinase D 2.7.1.90 diphosphate---fructose-6-phosphate 1-phosphotransferase E PRU_0792 diphosphate--fructose-6-phosphate 1-phosphotransferase K00895 E2.7.1.90; pyrophosphate--fructose-6-phosphate 1-phosphotransferase [EC:2.7.1.90] D 2.7.1.91 sphinganine kinase D 2.7.1.92 5-dehydro-2-deoxygluconokinase D 2.7.1.93 alkylglycerol kinase D 2.7.1.94 acylglycerol kinase D 2.7.1.95 kanamycin kinase D 2.7.1.100 S-methyl-5-thioribose kinase D 2.7.1.101 tagatose kinase D 2.7.1.102 hamamelose kinase D 2.7.1.103 viomycin kinase D 2.7.1.105 6-phosphofructo-2-kinase D 2.7.1.106 glucose-1,6-bisphosphate synthase D 2.7.1.107 diacylglycerol kinase (ATP dependent) D 2.7.1.108 dolichol kinase D 2.7.1.113 deoxyguanosine kinase D 2.7.1.114 AMP---thymidine kinase D 2.7.1.118 ADP---thymidine kinase D 2.7.1.119 hygromycin-B 7''-O-kinase D 2.7.1.121 phosphoenolpyruvate---glycerone phosphotransferase D 2.7.1.122 xylitol kinase D 2.7.1.127 inositol-trisphosphate 3-kinase D 2.7.1.130 tetraacyldisaccharide 4'-kinase E PRU_0309 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D 2.7.1.134 inositol-tetrakisphosphate 1-kinase D 2.7.1.136 macrolide 2'-kinase D 2.7.1.137 phosphatidylinositol 3-kinase D 2.7.1.138 ceramide kinase D 2.7.1.140 inositol-tetrakisphosphate 5-kinase D 2.7.1.142 glycerol-3-phosphate---glucose phosphotransferase D 2.7.1.143 diphosphate-purine nucleoside kinase D 2.7.1.144 tagatose-6-phosphate kinase D 2.7.1.145 deoxynucleoside kinase D 2.7.1.146 ADP-specific phosphofructokinase D 2.7.1.147 ADP-specific glucokinase D 2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase E PRU_0846 ispE; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase D 2.7.1.150 1-phosphatidylinositol-3-phosphate 5-kinase D 2.7.1.151 inositol-polyphosphate multikinase D 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase D 2.7.1.154 phosphatidylinositol-4-phosphate 3-kinase D 2.7.1.156 adenosylcobinamide kinase E PRU_1093 cobP; cobinamide kinase/cobinamide phosphate guanylyltransferase K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] D 2.7.1.157 N-acetylgalactosamine kinase D 2.7.1.158 inositol-pentakisphosphate 2-kinase D 2.7.1.159 inositol-1,3,4-trisphosphate 5/6-kinase D 2.7.1.160 2'-phosphotransferase D 2.7.1.161 CTP-dependent riboflavin kinase D 2.7.1.162 N-acetylhexosamine 1-kinase D 2.7.1.163 hygromycin B 4-O-kinase D 2.7.1.164 O-phosphoseryl-tRNASec kinase D 2.7.1.165 glycerate 2-kinase D 2.7.1.166 3-deoxy-D-manno-octulosonic acid kinase D 2.7.1.167 D-glycero-beta-D-manno-heptose-7-phosphate kinase D 2.7.1.168 D-glycero-alpha-D-manno-heptose-7-phosphate kinase D 2.7.1.169 pantoate kinase D 2.7.1.170 anhydro-N-acetylmuramic acid kinase D 2.7.1.171 protein-fructosamine 3-kinase D 2.7.1.172 protein-ribulosamine 3-kinase D 2.7.1.173 nicotinate riboside kinase D 2.7.1.174 diacylglycerol kinase (CTP dependent) D 2.7.1.175 maltokinase D 2.7.1.176 UDP-N-acetylglucosamine kinase D 2.7.1.177 L-threonine kinase D 2.7.1.- C 2.7.2 Phosphotransferases with a carboxy group as acceptor D 2.7.2.1 acetate kinase E PRU_2259 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D 2.7.2.2 carbamate kinase D 2.7.2.3 phosphoglycerate kinase E PRU_1634 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D 2.7.2.4 aspartate kinase E PRU_0480 lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4] E PRU_1016 thrA; aspartate kinase/homoserine dehydrogenase K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] D 2.7.2.6 formate kinase D 2.7.2.7 butyrate kinase E PRU_2349 buk; butyrate kinase K00929 E2.7.2.7; butyrate kinase [EC:2.7.2.7] D 2.7.2.8 acetylglutamate kinase E PRU_2621 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D 2.7.2.10 phosphoglycerate kinase (GTP) D 2.7.2.11 glutamate 5-kinase E PRU_2207 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D 2.7.2.12 acetate kinase (diphosphate) D 2.7.2.13 glutamate 1-kinase D 2.7.2.14 branched-chain-fatty-acid kinase D 2.7.2.15 propionate kinase D 2.7.2.- C 2.7.3 Phosphotransferases with a nitrogenous group as acceptor D 2.7.3.1 guanidinoacetate kinase D 2.7.3.2 creatine kinase D 2.7.3.3 arginine kinase D 2.7.3.4 taurocyamine kinase D 2.7.3.5 lombricine kinase D 2.7.3.6 hypotaurocyamine kinase D 2.7.3.7 opheline kinase D 2.7.3.8 ammonia kinase D 2.7.3.9 phosphoenolpyruvate---protein phosphotransferase D 2.7.3.10 agmatine kinase D 2.7.3.- C 2.7.4 Phosphotransferases with a phosphate group as acceptor D 2.7.4.1 polyphosphate kinase D 2.7.4.2 phosphomevalonate kinase D 2.7.4.3 adenylate kinase E PRU_2869 adk; adenylate kinase K00939 E2.7.4.3; adenylate kinase [EC:2.7.4.3] D 2.7.4.4 nucleoside-phosphate kinase D 2.7.4.6 nucleoside-diphosphate kinase D 2.7.4.7 phosphomethylpyrimidine kinase E PRU_0406 thiD; phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D 2.7.4.8 guanylate kinase E PRU_2547 guanylate kinase K00942 E2.7.4.8; guanylate kinase [EC:2.7.4.8] D 2.7.4.9 dTMP kinase D 2.7.4.10 nucleoside-triphosphate---adenylate kinase D 2.7.4.11 (deoxy)adenylate kinase D 2.7.4.12 T2-induced deoxynucleotide kinase D 2.7.4.13 (deoxy)nucleoside-phosphate kinase D 2.7.4.14 UMP/CMP kinase E PRU_1828 cmk; cytidylate kinase K00945 cmk; cytidylate kinase [EC:2.7.4.14] D 2.7.4.15 thiamine-diphosphate kinase D 2.7.4.16 thiamine-phosphate kinase E PRU_0311 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D 2.7.4.17 3-phosphoglyceroyl-phosphate---polyphosphate phosphotransferase D 2.7.4.18 farnesyl-diphosphate kinase D 2.7.4.19 5-methyldeoxycytidine-5'-phosphate kinase D 2.7.4.20 dolichyl-diphosphate---polyphosphate phosphotransferase D 2.7.4.21 inositol-hexakisphosphate kinase D 2.7.4.22 UMP kinase E PRU_1892 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D 2.7.4.23 ribose 1,5-bisphosphate phosphokinase D 2.7.4.24 diphosphoinositol-pentakisphosphate kinase D 2.7.4.25 (d)CMP kinase D 2.7.4.26 isopentenyl phosphate kinase D 2.7.4.27 [pyruvate, phosphate dikinase]-phosphate phosphotransferase D 2.7.4.28 [pyruvate, water dikinase]-phosphate phosphotransferase D 2.7.4.- C 2.7.6 Diphosphotransferases D 2.7.6.1 ribose-phosphate diphosphokinase E PRU_0673 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D 2.7.6.2 thiamine diphosphokinase D 2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase E PRU_1830 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D 2.7.6.4 nucleotide diphosphokinase D 2.7.6.5 GTP diphosphokinase E PRU_0013 RelA/SpoT family protein K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5] E PRU_1210 GTP diphosphokinase K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5] D 2.7.6.- C 2.7.7 Nucleotidyltransferases D 2.7.7.1 nicotinamide-nucleotide adenylyltransferase D 2.7.7.2 FAD synthetase E PRU_2617 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D 2.7.7.3 pantetheine-phosphate adenylyltransferase E PRU_2469 coaD; pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D 2.7.7.4 sulfate adenylyltransferase D 2.7.7.5 sulfate adenylyltransferase (ADP) D 2.7.7.6 DNA-directed RNA polymerase E PRU_2088 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] E PRU_2135 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] E PRU_2134 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] D 2.7.7.7 DNA-directed DNA polymerase E PRU_2485 polA; DNA-directed DNA polymerase K02335 DPO1; DNA polymerase I [EC:2.7.7.7] E PRU_1896 dnaE; DNA polymerase III subunit alpha K02337 DPO3A1; DNA polymerase III subunit alpha [EC:2.7.7.7] E PRU_0839 dnaN; DNA polymerase III subunit beta K02338 DPO3B; DNA polymerase III subunit beta [EC:2.7.7.7] E PRU_0540 holA; DNA polymerase III subunit delta K02340 DPO3D1; DNA polymerase III subunit delta [EC:2.7.7.7] E PRU_1701 DNA polymerase III K02341 DPO3D2; DNA polymerase III subunit delta' [EC:2.7.7.7] E PRU_0838 DNA polymerase III subunit epsilon K02342 DPO3E; DNA polymerase III subunit epsilon [EC:2.7.7.7] E PRU_1188 exonuclease K02342 DPO3E; DNA polymerase III subunit epsilon [EC:2.7.7.7] E PRU_2813 exonuclease K02342 DPO3E; DNA polymerase III subunit epsilon [EC:2.7.7.7] E PRU_1618 dnaX; DNA polymerase III subunits gamma and tau K02343 DPO3G; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] E PRU_0499 DNA polymerase IV K02346 DPO4; DNA polymerase IV [EC:2.7.7.7] D 2.7.7.8 polyribonucleotide nucleotidyltransferase E PRU_2633 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D 2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase D 2.7.7.10 UTP---hexose-1-phosphate uridylyltransferase D 2.7.7.11 UTP---xylose-1-phosphate uridylyltransferase D 2.7.7.12 UDP-glucose---hexose-1-phosphate uridylyltransferase D 2.7.7.13 mannose-1-phosphate guanylyltransferase E PRU_1376 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] E PRU_2758 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] D 2.7.7.14 ethanolamine-phosphate cytidylyltransferase D 2.7.7.15 choline-phosphate cytidylyltransferase D 2.7.7.18 nicotinate-nucleotide adenylyltransferase E PRU_2546 nadD; nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D 2.7.7.19 polynucleotide adenylyltransferase D 2.7.7.22 mannose-1-phosphate guanylyltransferase (GDP) D 2.7.7.23 UDP-N-acetylglucosamine diphosphorylase D 2.7.7.24 glucose-1-phosphate thymidylyltransferase E PRU_1543 nucleotidyltransferase family protein K00973 E2.7.7.24; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] E PRU_0229 rfbA; glucose-1-phosphate thymidylyltransferase K00973 E2.7.7.24; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D 2.7.7.27 glucose-1-phosphate adenylyltransferase D 2.7.7.28 nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase D 2.7.7.30 fucose-1-phosphate guanylyltransferase D 2.7.7.31 DNA nucleotidylexotransferase D 2.7.7.32 galactose-1-phosphate thymidylyltransferase D 2.7.7.33 glucose-1-phosphate cytidylyltransferase E PRU_0434 glucose-1-phosphate cytidylyltransferase K00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33] D 2.7.7.34 glucose-1-phosphate guanylyltransferase D 2.7.7.35 ribose-5-phosphate adenylyltransferase D 2.7.7.36 aldose-1-phosphate adenylyltransferase D 2.7.7.37 aldose-1-phosphate nucleotidyltransferase D 2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase E PRU_1308 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D 2.7.7.39 glycerol-3-phosphate cytidylyltransferase D 2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase D 2.7.7.41 phosphatidate cytidylyltransferase E PRU_0045 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D 2.7.7.42 [glutamate---ammonia-ligase] adenylyltransferase D 2.7.7.43 N-acylneuraminate cytidylyltransferase D 2.7.7.44 glucuronate-1-phosphate uridylyltransferase D 2.7.7.45 guanosine-triphosphate guanylyltransferase D 2.7.7.46 gentamicin 2''-nucleotidyltransferase D 2.7.7.47 streptomycin 3''-adenylyltransferase D 2.7.7.48 RNA-directed RNA polymerase D 2.7.7.49 RNA-directed DNA polymerase D 2.7.7.50 mRNA guanylyltransferase D 2.7.7.51 adenylylsulfate---ammonia adenylyltransferase D 2.7.7.52 RNA uridylyltransferase D 2.7.7.53 ATP adenylyltransferase D 2.7.7.54 phenylalanine adenylyltransferase D 2.7.7.55 anthranilate adenylyltransferase D 2.7.7.56 tRNA nucleotidyltransferase D 2.7.7.57 N-methylphosphoethanolamine cytidylyltransferase D 2.7.7.58 (2,3-dihydroxybenzoyl)adenylate synthase D 2.7.7.59 [protein-PII] uridylyltransferase D 2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase E PRU_2537 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] E PRU_1943 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D 2.7.7.61 citrate lyase holo-[acyl-carrier protein] synthase D 2.7.7.62 adenosylcobinamide-phosphate guanylyltransferase E PRU_1093 cobP; cobinamide kinase/cobinamide phosphate guanylyltransferase K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] D 2.7.7.63 lipoate---protein ligase E PRU_2049 biotin/lipoate A/B protein ligase family protein K03800 lplA; lipoate-protein ligase A [EC:2.7.7.63] D 2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase D 2.7.7.65 diguanylate cyclase D 2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase D 2.7.7.67 CDP-archaeol synthase D 2.7.7.68 2-phospho-L-lactate guanylyltransferase D 2.7.7.69 GDP-L-galactose phosphorylase D 2.7.7.70 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase D 2.7.7.71 D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase D 2.7.7.72 CCA tRNA nucleotidyltransferase D 2.7.7.73 sulfur carrier protein ThiS adenylyltransferase D 2.7.7.74 1L-myo-inositol 1-phosphate cytidylyltransferase D 2.7.7.75 molybdopterin adenylyltransferase D 2.7.7.76 molybdenum cofactor cytidylyltransferase D 2.7.7.77 molybdenum cofactor guanylyltransferase D 2.7.7.78 GDP-D-glucose phosphorylase D 2.7.7.79 tRNAHis guanylyltransferase D 2.7.7.80 molybdopterin-synthase adenylyltransferase D 2.7.7.81 pseudaminic acid cytidylyltransferase D 2.7.7.82 CMP-N,N'-diacetyllegionaminic acid synthase D 2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase D 2.7.7.84 2'-5' oligoadenylate synthase D 2.7.7.- E PRU_1995 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.-] C 2.7.8 Transferases for other substituted phosphate groups D 2.7.8.1 ethanolaminephosphotransferase D 2.7.8.2 diacylglycerol cholinephosphotransferase D 2.7.8.3 ceramide cholinephosphotransferase D 2.7.8.4 serine-phosphoethanolamine synthase D 2.7.8.5 CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase D 2.7.8.6 undecaprenyl-phosphate galactose phosphotransferase D 2.7.8.7 holo-[acyl-carrier-protein] synthase D 2.7.8.8 CDP-diacylglycerol---serine O-phosphatidyltransferase E PRU_1894 CDP-diacylglycerol--serine O-phosphatidyltransferase K00998 pssA; phosphatidylserine synthase [EC:2.7.8.8] D 2.7.8.9 phosphomannan mannosephosphotransferase D 2.7.8.10 sphingosine cholinephosphotransferase D 2.7.8.11 CDP-diacylglycerol---inositol 3-phosphatidyltransferase D 2.7.8.12 CDP-glycerol glycerophosphotransferase D 2.7.8.13 phospho-N-acetylmuramoyl-pentapeptide-transferase E PRU_2329 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D 2.7.8.14 CDP-ribitol ribitolphosphotransferase D 2.7.8.15 UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminephosphotransferase D 2.7.8.17 UDP-N-acetylglucosamine---lysosomal-enzyme N-acetylglucosaminephosphotransferase D 2.7.8.18 UDP-galactose---UDP-N-acetylglucosamine galactose phosphotransferase D 2.7.8.19 UDP-glucose---glycoprotein glucose phosphotransferase D 2.7.8.20 phosphatidylglycerol---membrane-oligosaccharide glycerophosphotransferase D 2.7.8.21 membrane-oligosaccharide glycerophosphotransferase D 2.7.8.22 1-alkenyl-2-acylglycerol choline phosphotransferase D 2.7.8.23 carboxyvinyl-carboxyphosphonate phosphorylmutase D 2.7.8.24 phosphatidylcholine synthase D 2.7.8.25 triphosphoribosyl-dephospho-CoA synthase D 2.7.8.26 adenosylcobinamide-GDP ribazoletransferase E PRU_1092 cobS; cobalamin-5-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D 2.7.8.27 sphingomyelin synthase D 2.7.8.28 2-phospho-L-lactate transferase D 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase D 2.7.8.30 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase D 2.7.8.31 undecaprenyl-phosphate glucose phosphotransferase D 2.7.8.32 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase D 2.7.8.33 UDP-N-acetylglucosamine---undecaprenyl-phosphate N-acetylglucosaminephosphotransferase D 2.7.8.34 CDP-L-myo-inositol myo-inositolphosphotransferase D 2.7.8.35 UDP-N-acetylglucosamine---decaprenyl-phosphate N-acetylglucosaminephosphotransferase D 2.7.8.36 undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase D 2.7.8.37 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase D 2.7.8.38 archaetidylserine synthase D 2.7.8.- E PRU_1994 phospholipase D K06131 cls; cardiolipin synthase [EC:2.7.8.-] E PRU_1948 4'-phosphopantetheinyl transferase family protein K06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-] E PRU_2539 licD protein K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-] E PRU_1430 LicD family protein K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-] E PRU_2909 LicD family protein K07271 licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-] C 2.7.9 Phosphotransferases with paired acceptors D 2.7.9.1 pyruvate, phosphate dikinase E PRU_1512 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1] D 2.7.9.2 pyruvate, water dikinase D 2.7.9.3 selenide, water dikinase D 2.7.9.4 alpha-glucan, water dikinase D 2.7.9.5 phosphoglucan, water dikinase D 2.7.9.- C 2.7.10 Protein-tyrosine kinases D 2.7.10.1 receptor protein-tyrosine kinase D 2.7.10.2 non-specific protein-tyrosine kinase D 2.7.10.- C 2.7.11 Protein-serine/threonine kinases D 2.7.11.1 non-specific serine/threonine protein kinase E PRU_2420 HipA domain-containing protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] E PRU_1495 HipA domain-containing protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] E PRU_1967 hypothetical protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] E PRU_1968 HipA domain-containing protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] D 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase D 2.7.11.3 dephospho-[reductase kinase] kinase D 2.7.11.4 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase D 2.7.11.5 [isocitrate dehydrogenase (NADP+)] kinase D 2.7.11.6 [tyrosine 3-monooxygenase] kinase D 2.7.11.7 myosin-heavy-chain kinase D 2.7.11.8 Fas-activated serine/threonine kinase D 2.7.11.9 Goodpasture-antigen-binding protein kinase D 2.7.11.10 IkappaB kinase D 2.7.11.11 cAMP-dependent protein kinase D 2.7.11.12 cGMP-dependent protein kinase D 2.7.11.13 protein kinase C D 2.7.11.14 rhodopsin kinase D 2.7.11.15 beta-adrenergic-receptor kinase D 2.7.11.16 G-protein-coupled receptor kinase D 2.7.11.17 Ca2+/calmodulin-dependent protein kinase D 2.7.11.18 myosin-light-chain kinase D 2.7.11.19 phosphorylase kinase D 2.7.11.20 elongation factor 2 kinase D 2.7.11.21 polo kinase D 2.7.11.22 cyclin-dependent kinase D 2.7.11.23 [RNA-polymerase]-subunit kinase D 2.7.11.24 mitogen-activated protein kinase D 2.7.11.25 mitogen-activated protein kinase kinase kinase D 2.7.11.26 tau-protein kinase D 2.7.11.27 [acetyl-CoA carboxylase] kinase D 2.7.11.28 tropomyosin kinase D 2.7.11.29 low-density-lipoprotein receptor kinase D 2.7.11.30 receptor protein serine/threonine kinase D 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase D 2.7.11.32 [pyruvate, phosphate dikinase] kinase D 2.7.11.33 [pyruvate, water dikinase] kinase D 2.7.11.- C 2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) D 2.7.12.1 dual-specificity kinase D 2.7.12.2 mitogen-activated protein kinase kinase C 2.7.13 Protein-histidine kinases D 2.7.13.1 protein-histidine pros-kinase D 2.7.13.2 protein-histidine tele-kinase D 2.7.13.3 histidine kinase E PRU_0614 rprX; sensor histidine kinase RprX K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] E PRU_2319 sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] D 2.7.13.- C 2.7.99 Other protein kinases D 2.7.99.1 triphosphate---protein phosphotransferase C 2.7.- Transferring phosphorus-containing groups D 2.7.-.- E PRU_0160 LAO/AO transport system ATPase K07588 argK; LAO/AO transport system kinase [EC:2.7.-.-] B 2.8 Transferring sulfur-containing groups C 2.8.1 Sulfurtransferases D 2.8.1.1 thiosulfate sulfurtransferase D 2.8.1.2 3-mercaptopyruvate sulfurtransferase D 2.8.1.3 thiosulfate---thiol sulfurtransferase D 2.8.1.4 tRNA sulfurtransferase D 2.8.1.5 thiosulfate---dithiol sulfurtransferase D 2.8.1.6 biotin synthase D 2.8.1.7 cysteine desulfurase E PRU_2376 sufS; cysteine desulfurase SufS K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D 2.8.1.8 lipoyl synthase D 2.8.1.9 molybdenum cofactor sulfurtransferase D 2.8.1.10 thiazole synthase D 2.8.1.11 molybdopterin synthase sulfurtransferase D 2.8.1.12 molybdopterin synthase D 2.8.1.- E PRU_0077 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-specific 2-thiouridylase [EC:2.8.1.-] C 2.8.2 Sulfotransferases D 2.8.2.1 aryl sulfotransferase D 2.8.2.2 alcohol sulfotransferase D 2.8.2.3 amine sulfotransferase D 2.8.2.4 estrone sulfotransferase D 2.8.2.5 chondroitin 4-sulfotransferase D 2.8.2.6 choline sulfotransferase D 2.8.2.7 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase D 2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase D 2.8.2.9 tyrosine-ester sulfotransferase D 2.8.2.10 Renilla-luciferin sulfotransferase D 2.8.2.11 galactosylceramide sulfotransferase D 2.8.2.13 psychosine sulfotransferase D 2.8.2.14 bile-salt sulfotransferase D 2.8.2.15 steroid sulfotransferase D 2.8.2.16 thiol sulfotransferase D 2.8.2.17 chondroitin 6-sulfotransferase D 2.8.2.18 cortisol sulfotransferase D 2.8.2.19 triglucosylalkylacylglycerol sulfotransferase D 2.8.2.20 protein-tyrosine sulfotransferase D 2.8.2.21 keratan sulfotransferase D 2.8.2.22 aryl-sulfate sulfotransferase D 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1 D 2.8.2.24 desulfoglucosinolate sulfotransferase D 2.8.2.25 flavonol 3-sulfotransferase D 2.8.2.26 quercetin-3-sulfate 3'-sulfotransferase D 2.8.2.27 quercetin-3-sulfate 4'-sulfotransferase D 2.8.2.28 quercetin-3,3'-bissulfate 7-sulfotransferase D 2.8.2.29 [heparan sulfate]-glucosamine 3-sulfotransferase 2 D 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3 D 2.8.2.31 petromyzonol sulfotransferase D 2.8.2.32 scymnol sulfotransferase D 2.8.2.33 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase D 2.8.2.34 glycochenodeoxycholate sulfotransferase D 2.8.2.35 dermatan 4-sulfotransferase D 2.8.2.- C 2.8.3 CoA-transferases D 2.8.3.1 propionate CoA-transferase D 2.8.3.2 oxalate CoA-transferase D 2.8.3.3 malonate CoA-transferase D 2.8.3.5 3-oxoacid CoA-transferase D 2.8.3.6 3-oxoadipate CoA-transferase D 2.8.3.7 succinate---citramalate CoA-transferase D 2.8.3.8 acetate CoA-transferase D 2.8.3.9 butyrate---acetoacetate CoA-transferase D 2.8.3.10 citrate CoA-transferase D 2.8.3.11 citramalate CoA-transferase D 2.8.3.12 glutaconate CoA-transferase D 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase D 2.8.3.14 5-hydroxypentanoate CoA-transferase D 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase D 2.8.3.16 formyl-CoA transferase D 2.8.3.17 cinnamoyl-CoA:phenyllactate CoA-transferase D 2.8.3.- C 2.8.4 Transferring alkylthio groups D 2.8.4.1 coenzyme-B sulfoethylthiotransferase D 2.8.4.2 arsenate-mycothiol transferase B 2.9 Transferring selenium-containing groups C 2.9.1 Selenotransferases D 2.9.1.1 L-seryl-tRNASec selenium transferase D 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase D 2.9.1.- B 2.10 Transferring molybdenum- or tungsten-containing groups C 2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors D 2.10.1.1 molybdopterin molybdotransferase B 2.- C 2.-.- D 2.-.-.- E PRU_0752 rimO; 30S ribosomal protein S12 methylthiotransferase RimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.-.-.-] # A3. Hydrolases B 3.1 Acting on ester bonds C 3.1.1 Carboxylic-ester hydrolases D 3.1.1.1 carboxylesterase D 3.1.1.2 arylesterase D 3.1.1.3 triacylglycerol lipase D 3.1.1.4 phospholipase A2 D 3.1.1.5 lysophospholipase D 3.1.1.6 acetylesterase D 3.1.1.7 acetylcholinesterase D 3.1.1.8 cholinesterase D 3.1.1.10 tropinesterase D 3.1.1.11 pectinesterase E PRU_0012 pectinesterase K01051 E3.1.1.11; pectinesterase [EC:3.1.1.11] D 3.1.1.13 sterol esterase D 3.1.1.14 chlorophyllase D 3.1.1.15 L-arabinonolactonase D 3.1.1.17 gluconolactonase D 3.1.1.19 uronolactonase D 3.1.1.20 tannase D 3.1.1.22 hydroxybutyrate-dimer hydrolase D 3.1.1.23 acylglycerol lipase D 3.1.1.24 3-oxoadipate enol-lactonase D 3.1.1.25 1,4-lactonase D 3.1.1.26 galactolipase D 3.1.1.27 4-pyridoxolactonase D 3.1.1.28 acylcarnitine hydrolase D 3.1.1.29 aminoacyl-tRNA hydrolase E PRU_0249 pth; aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D 3.1.1.30 D-arabinonolactonase D 3.1.1.31 6-phosphogluconolactonase D 3.1.1.32 phospholipase A1 D 3.1.1.33 6-acetylglucose deacetylase D 3.1.1.34 lipoprotein lipase D 3.1.1.35 dihydrocoumarin hydrolase D 3.1.1.36 limonin-D-ring-lactonase D 3.1.1.37 steroid-lactonase D 3.1.1.38 triacetate-lactonase D 3.1.1.39 actinomycin lactonase D 3.1.1.40 orsellinate-depside hydrolase D 3.1.1.41 cephalosporin-C deacetylase D 3.1.1.42 chlorogenate hydrolase D 3.1.1.43 alpha-amino-acid esterase D 3.1.1.44 4-methyloxaloacetate esterase D 3.1.1.45 carboxymethylenebutenolidase D 3.1.1.46 deoxylimonate A-ring-lactonase D 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase D 3.1.1.48 fusarinine-C ornithinesterase D 3.1.1.49 sinapine esterase D 3.1.1.50 wax-ester hydrolase D 3.1.1.51 phorbol-diester hydrolase D 3.1.1.52 phosphatidylinositol deacylase D 3.1.1.53 sialate O-acetylesterase E PRU_2599 sialic acid-specific 9-O-acetylesterase-like protein K05970 E3.1.1.53; sialate O-acetylesterase [EC:3.1.1.53] E PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein K05970 E3.1.1.53; sialate O-acetylesterase [EC:3.1.1.53] D 3.1.1.54 acetoxybutynylbithiophene deacetylase D 3.1.1.55 acetylsalicylate deacetylase D 3.1.1.56 methylumbelliferyl-acetate deacetylase D 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase D 3.1.1.58 N-acetylgalactosaminoglycan deacetylase D 3.1.1.59 juvenile-hormone esterase D 3.1.1.60 bis(2-ethylhexyl)phthalate esterase D 3.1.1.61 protein-glutamate methylesterase D 3.1.1.63 11-cis-retinyl-palmitate hydrolase D 3.1.1.64 retinoid isomerohydrolase D 3.1.1.65 L-rhamnono-1,4-lactonase D 3.1.1.66 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase D 3.1.1.67 fatty-acyl-ethyl-ester synthase D 3.1.1.68 xylono-1,4-lactonase D 3.1.1.70 cetraxate benzylesterase D 3.1.1.71 acetylalkylglycerol acetylhydrolase D 3.1.1.72 acetylxylan esterase D 3.1.1.73 feruloyl esterase D 3.1.1.74 cutinase D 3.1.1.75 poly(3-hydroxybutyrate) depolymerase D 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase D 3.1.1.77 acyloxyacyl hydrolase D 3.1.1.78 polyneuridine-aldehyde esterase D 3.1.1.79 hormone-sensitive lipase D 3.1.1.80 acetylajmaline esterase D 3.1.1.81 quorum-quenching N-acyl-homoserine lactonase D 3.1.1.82 pheophorbidase D 3.1.1.83 monoterpene epsilon-lactone hydrolase D 3.1.1.84 cocaine esterase D 3.1.1.85 pimelyl-[acyl-carrier protein] methyl ester esterase D 3.1.1.86 rhamnogalacturonan acetylesterase D 3.1.1.87 fumonisin B1 esterase D 3.1.1.88 pyrethroid hydrolase D 3.1.1.89 protein phosphatase methylesterase-1 D 3.1.1.90 all-trans-retinyl ester 13-cis isomerohydrolase D 3.1.1.91 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase D 3.1.1.92 4-sulfomuconolactone hydrolase D 3.1.1.93 mycophenolic acid acyl-glucuronide esterase D 3.1.1.- E PRU_1600 carboxylesterase family protein K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] E PRU_0408 carboxylesterase K03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-] C 3.1.2 Thioester hydrolases D 3.1.2.1 acetyl-CoA hydrolase D 3.1.2.2 palmitoyl-CoA hydrolase D 3.1.2.3 succinyl-CoA hydrolase D 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase D 3.1.2.5 hydroxymethylglutaryl-CoA hydrolase D 3.1.2.6 hydroxyacylglutathione hydrolase D 3.1.2.7 glutathione thiolesterase D 3.1.2.10 formyl-CoA hydrolase D 3.1.2.11 acetoacetyl-CoA hydrolase D 3.1.2.12 S-formylglutathione hydrolase D 3.1.2.13 S-succinylglutathione hydrolase D 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase D 3.1.2.15 ubiquitin thiolesterase D 3.1.2.16 citrate-lyase deacetylase D 3.1.2.17 (S)-methylmalonyl-CoA hydrolase D 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase D 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase D 3.1.2.20 acyl-CoA hydrolase D 3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase D 3.1.2.22 palmitoyl[protein] hydrolase D 3.1.2.23 4-hydroxybenzoyl-CoA thioesterase D 3.1.2.25 phenylacetyl-CoA hydrolase D 3.1.2.26 bile-acid-CoA hydrolase D 3.1.2.27 choloyl-CoA hydrolase D 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase D 3.1.2.29 fluoroacetyl-CoA thioesterase D 3.1.2.- E PRU_1668 thioesterase family protein K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-] E PRU_2385 hypothetical protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] E PRU_0655 thioesterase family protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-] C 3.1.3 Phosphoric-monoester hydrolases D 3.1.3.1 alkaline phosphatase D 3.1.3.2 acid phosphatase D 3.1.3.3 phosphoserine phosphatase E PRU_1999 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D 3.1.3.4 phosphatidate phosphatase D 3.1.3.5 5'-nucleotidase E PRU_0018 surE; acid phosphatase SurE K03787 surE; 5'-nucleotidase [EC:3.1.3.5] D 3.1.3.6 3'-nucleotidase D 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase D 3.1.3.8 3-phytase D 3.1.3.9 glucose-6-phosphatase D 3.1.3.10 glucose-1-phosphatase E PRU_2794 agp; glucose-1-phosphatase K01085 agp; glucose-1-phosphatase [EC:3.1.3.10] D 3.1.3.11 fructose-bisphosphatase E PRU_0476 fructose-1 K04041 fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11] D 3.1.3.12 trehalose-phosphatase D 3.1.3.13 bisphosphoglycerate phosphatase D 3.1.3.14 methylphosphothioglycerate phosphatase D 3.1.3.15 histidinol-phosphatase E PRU_0455 hisB; histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase K01089 hisB; imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] D 3.1.3.16 phosphoprotein phosphatase D 3.1.3.17 [phosphorylase] phosphatase D 3.1.3.18 phosphoglycolate phosphatase E PRU_1370 HAD-superfamily hydrolase K01091 E3.1.3.18; phosphoglycolate phosphatase [EC:3.1.3.18] E PRU_0373 haloacid dehalogenase-like hydrolase domain-containing protein K01091 E3.1.3.18; phosphoglycolate phosphatase [EC:3.1.3.18] D 3.1.3.19 glycerol-2-phosphatase D 3.1.3.20 phosphoglycerate phosphatase D 3.1.3.21 glycerol-1-phosphatase D 3.1.3.22 mannitol-1-phosphatase D 3.1.3.23 sugar-phosphatase D 3.1.3.24 sucrose-phosphate phosphatase D 3.1.3.25 inositol-phosphate phosphatase E PRU_1146 inositol-1-monophosphatase/HD domain-containing protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D 3.1.3.26 4-phytase D 3.1.3.27 phosphatidylglycerophosphatase D 3.1.3.28 ADP-phosphoglycerate phosphatase D 3.1.3.29 N-acylneuraminate-9-phosphatase D 3.1.3.31 nucleotidase D 3.1.3.32 polynucleotide 3'-phosphatase D 3.1.3.33 polynucleotide 5'-phosphatase D 3.1.3.34 deoxynucleotide 3'-phosphatase D 3.1.3.35 thymidylate 5'-phosphatase D 3.1.3.36 phosphoinositide 5-phosphatase D 3.1.3.37 sedoheptulose-bisphosphatase D 3.1.3.38 3-phosphoglycerate phosphatase D 3.1.3.39 streptomycin-6-phosphatase D 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase D 3.1.3.41 4-nitrophenylphosphatase D 3.1.3.42 [glycogen-synthase-D] phosphatase D 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase D 3.1.3.44 [acetyl-CoA carboxylase]-phosphatase D 3.1.3.45 3-deoxy-manno-octulosonate-8-phosphatase E PRU_1206 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45] D 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase D 3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase D 3.1.3.48 protein-tyrosine-phosphatase E PRU_0901 low molecular weight phosphotyrosine protein phosphatase K01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48] D 3.1.3.49 [pyruvate kinase]-phosphatase D 3.1.3.50 sorbitol-6-phosphatase D 3.1.3.51 dolichyl-phosphatase D 3.1.3.52 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase D 3.1.3.53 [myosin-light-chain] phosphatase D 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase D 3.1.3.55 caldesmon-phosphatase D 3.1.3.56 inositol-polyphosphate 5-phosphatase D 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase D 3.1.3.58 sugar-terminal-phosphatase D 3.1.3.59 alkylacetylglycerophosphatase D 3.1.3.60 phosphoenolpyruvate phosphatase D 3.1.3.62 multiple inositol-polyphosphate phosphatase D 3.1.3.63 2-carboxy-D-arabinitol-1-phosphatase D 3.1.3.64 phosphatidylinositol-3-phosphatase D 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase D 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase D 3.1.3.68 2-deoxyglucose-6-phosphatase D 3.1.3.69 glucosylglycerol 3-phosphatase D 3.1.3.70 mannosyl-3-phosphoglycerate phosphatase D 3.1.3.71 2-phosphosulfolactate phosphatase D 3.1.3.72 5-phytase D 3.1.3.73 adenosylcobalamin/alpha-ribazole phosphatase D 3.1.3.74 pyridoxal phosphatase D 3.1.3.75 phosphoethanolamine/phosphocholine phosphatase D 3.1.3.76 lipid-phosphate phosphatase D 3.1.3.77 acireductone synthase D 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase D 3.1.3.79 mannosylfructose-phosphate phosphatase D 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase D 3.1.3.81 diacylglycerol diphosphate phosphatase D 3.1.3.82 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase D 3.1.3.83 D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphatase D 3.1.3.84 ADP-ribose 1''-phosphate phosphatase D 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase D 3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase D 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase D 3.1.3.88 5''-phosphoribostamycin phosphatase D 3.1.3.- C 3.1.4 Phosphoric-diester hydrolases D 3.1.4.1 phosphodiesterase I D 3.1.4.2 glycerophosphocholine phosphodiesterase D 3.1.4.3 phospholipase C D 3.1.4.4 phospholipase D D 3.1.4.11 phosphoinositide phospholipase C D 3.1.4.12 sphingomyelin phosphodiesterase D 3.1.4.13 serine-ethanolaminephosphate phosphodiesterase D 3.1.4.14 [acyl-carrier-protein] phosphodiesterase D 3.1.4.15 adenylyl-[glutamate---ammonia ligase] hydrolase D 3.1.4.16 2',3'-cyclic-nucleotide 2'-phosphodiesterase E PRU_1310 2' K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] D 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase D 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase D 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase D 3.1.4.38 glycerophosphocholine cholinephosphodiesterase D 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase D 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase D 3.1.4.41 sphingomyelin phosphodiesterase D D 3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase D 3.1.4.43 glycerophosphoinositol inositolphosphodiesterase D 3.1.4.44 glycerophosphoinositol glycerophosphodiesterase D 3.1.4.45 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase D 3.1.4.46 glycerophosphodiester phosphodiesterase D 3.1.4.48 dolichylphosphate-glucose phosphodiesterase D 3.1.4.49 dolichylphosphate-mannose phosphodiesterase D 3.1.4.50 glycosylphosphatidylinositol phospholipase D D 3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase D 3.1.4.52 cyclic-guanylate-specific phosphodiesterase D 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase D 3.1.4.54 N-acetylphosphatidylethanolamine-hydrolysing phospholipase D D 3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase E PRU_0585 phnP protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] D 3.1.4.- C 3.1.5 Triphosphoric-monoester hydrolases D 3.1.5.1 dGTPase E PRU_2915 deoxyguanosinetriphosphate triphosphohydrolase K01129 dgt; dGTPase [EC:3.1.5.1] C 3.1.6 Sulfuric-ester hydrolases D 3.1.6.1 arylsulfatase D 3.1.6.2 steryl-sulfatase D 3.1.6.3 glycosulfatase D 3.1.6.4 N-acetylgalactosamine-6-sulfatase D 3.1.6.6 choline-sulfatase D 3.1.6.7 cellulose-polysulfatase D 3.1.6.8 cerebroside-sulfatase D 3.1.6.9 chondro-4-sulfatase D 3.1.6.10 chondro-6-sulfatase D 3.1.6.11 disulfoglucosamine-6-sulfatase D 3.1.6.12 N-acetylgalactosamine-4-sulfatase D 3.1.6.13 iduronate-2-sulfatase D 3.1.6.14 N-acetylglucosamine-6-sulfatase D 3.1.6.15 N-sulfoglucosamine-3-sulfatase D 3.1.6.16 monomethyl-sulfatase D 3.1.6.17 D-lactate-2-sulfatase D 3.1.6.18 glucuronate-2-sulfatase D 3.1.6.- C 3.1.7 Diphosphoric-monoester hydrolases D 3.1.7.1 prenyl-diphosphatase D 3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase D 3.1.7.3 monoterpenyl-diphosphatase D 3.1.7.5 geranylgeranyl diphosphate diphosphatase D 3.1.7.6 farnesyl diphosphatase D 3.1.7.7 drimenol cyclase D 3.1.7.8 tuberculosinol synthase D 3.1.7.9 isotuberculosinol synthase D 3.1.7.10 (13E)-labda-7,13-dien-15-ol synthase D 3.1.7.11 geranyl diphosphate diphosphatase C 3.1.8 Phosphoric-triester hydrolases D 3.1.8.1 aryldialkylphosphatase D 3.1.8.2 diisopropyl-fluorophosphatase C 3.1.11 Exodeoxyribonucleases producing 5'-phosphomonoesters D 3.1.11.1 exodeoxyribonuclease I D 3.1.11.2 exodeoxyribonuclease III E PRU_1657 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D 3.1.11.3 exodeoxyribonuclease (lambda-induced) D 3.1.11.4 exodeoxyribonuclease (phage SP3-induced) D 3.1.11.5 exodeoxyribonuclease V D 3.1.11.6 exodeoxyribonuclease VII E PRU_0168 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E PRU_0167 xseB; exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D 3.1.11.- C 3.1.13 Exoribonucleases producing 5'-phosphomonoesters D 3.1.13.1 exoribonuclease II D 3.1.13.2 exoribonuclease H D 3.1.13.3 oligonucleotidase D 3.1.13.4 poly(A)-specific ribonuclease D 3.1.13.5 ribonuclease D D 3.1.13.- C 3.1.14 Exoribonucleases producing 3'-phosphomonoesters D 3.1.14.1 yeast ribonuclease C 3.1.15 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters D 3.1.15.1 venom exonuclease C 3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters D 3.1.16.1 spleen exonuclease C 3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters D 3.1.21.1 deoxyribonuclease I D 3.1.21.2 deoxyribonuclease IV (phage-T4-induced) D 3.1.21.3 type I site-specific deoxyribonuclease E PRU_2890 type I restriction-modification system K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] E PRU_2889 type I restriction-modification system subunit S K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D 3.1.21.4 type II site-specific deoxyribonuclease D 3.1.21.5 type III site-specific deoxyribonuclease D 3.1.21.6 CC-preferring endodeoxyribonuclease D 3.1.21.7 deoxyribonuclease V D 3.1.21.- E PRU_1824 NUDIX family hydrolase K03424 tatD; TatD DNase family protein [EC:3.1.21.-] C 3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters D 3.1.22.1 deoxyribonuclease II D 3.1.22.2 Aspergillus deoxyribonuclease K1 D 3.1.22.4 crossover junction endodeoxyribonuclease E PRU_0827 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.22.4] D 3.1.22.5 deoxyribonuclease X D 3.1.22.- C 3.1.25 Site-specific endodeoxyribonucleases that are specific for altered bases D 3.1.25.1 deoxyribonuclease (pyrimidine dimer) D 3.1.25.- C 3.1.26 Endoribonucleases producing 5'-phosphomonoesters D 3.1.26.1 Physarum polycephalum ribonuclease D 3.1.26.2 ribonuclease alpha D 3.1.26.3 ribonuclease III E PRU_2560 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D 3.1.26.4 ribonuclease H E PRU_2378 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D 3.1.26.5 ribonuclease P E PRU_2297 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D 3.1.26.6 ribonuclease IV D 3.1.26.7 ribonuclease P4 D 3.1.26.8 ribonuclease M5 D 3.1.26.9 ribonuclease [poly-(U)-specific] D 3.1.26.10 ribonuclease IX D 3.1.26.11 tRNase Z E PRU_1411 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11] D 3.1.26.12 ribonuclease E D 3.1.26.13 retroviral ribonuclease H D 3.1.26.- E PRU_0682 ribonuclease K08301 rng; ribonuclease G [EC:3.1.26.-] C 3.1.27 Endoribonucleases producing 3'-phosphomonoesters D 3.1.27.1 ribonuclease T2 D 3.1.27.2 Bacillus subtilis ribonuclease D 3.1.27.3 ribonuclease T1 D 3.1.27.4 ribonuclease U2 D 3.1.27.5 pancreatic ribonuclease D 3.1.27.6 Enterobacter ribonuclease D 3.1.27.7 ribonuclease F D 3.1.27.8 ribonuclease V D 3.1.27.9 tRNA-intron endonuclease D 3.1.27.10 rRNA endonuclease D 3.1.27.- C 3.1.30 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters D 3.1.30.1 Aspergillus nuclease S1 D 3.1.30.2 Serratia marcescens nuclease C 3.1.31 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters D 3.1.31.1 micrococcal nuclease C 3.1.- Acting on ester bonds D 3.1.-.- E PRU_0590 hypothetical protein K07447 ruvX; putative holliday junction resolvase [EC:3.1.-.-] E PRU_0358 DNA mismatch endonuclease Vsr family protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] E PRU_0555 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E PRU_2480 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] E PRU_2753 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.-.-] B 3.2 Glycosylases C 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds D 3.2.1.1 alpha-amylase E PRU_1659 family 57 glycosyl hydrolase K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1] D 3.2.1.2 beta-amylase D 3.2.1.3 glucan 1,4-alpha-glucosidase D 3.2.1.4 cellulase E PRU_1737 M42 subfamily peptidase K01179 E3.2.1.4; endoglucanase [EC:3.2.1.4] D 3.2.1.6 endo-1,3(4)-beta-glucanase D 3.2.1.7 inulinase D 3.2.1.8 endo-1,4-beta-xylanase D 3.2.1.10 oligo-1,6-glucosidase D 3.2.1.11 dextranase D 3.2.1.14 chitinase D 3.2.1.15 polygalacturonase D 3.2.1.17 lysozyme E PRU_1883 lysozyme K01185 E3.2.1.17; lysozyme [EC:3.2.1.17] D 3.2.1.18 exo-alpha-sialidase D 3.2.1.20 alpha-glucosidase E PRU_0270 alpha-glucosidase family protein K01187 E3.2.1.20; alpha-glucosidase [EC:3.2.1.20] D 3.2.1.21 beta-glucosidase E PRU_2786 family 3 glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_2590 family 3 glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_1956 family 3 glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_1167 family 3 glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_0416 bglX; beta-glucosidase K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_2693 glucan 1 K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_2730 1 K05349 bglX; beta-glucosidase [EC:3.2.1.21] E PRU_1940 family 3 glycosyl hydrolase K05349 bglX; beta-glucosidase [EC:3.2.1.21] D 3.2.1.22 alpha-galactosidase E PRU_2514 alpha-galactosidase K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22] D 3.2.1.23 beta-galactosidase E PRU_1522 beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] E PRU_2769 family 2 glycosyl hydrolase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] E PRU_1079 family 2 glycosyl hydrolase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] E PRU_0693 lacZ; beta-galactosidase K01190 lacZ; beta-galactosidase [EC:3.2.1.23] E PRU_0082 beta-galactosidase K12308 bgaB; beta-galactosidase [EC:3.2.1.23] D 3.2.1.24 alpha-mannosidase E PRU_2181 family 38 glycosyl hydrolase/DS domain-containing protein K01191 E3.2.1.24; alpha-mannosidase [EC:3.2.1.24] D 3.2.1.25 beta-mannosidase D 3.2.1.26 beta-fructofuranosidase D 3.2.1.28 alpha,alpha-trehalase D 3.2.1.31 beta-glucuronidase E PRU_2313 family 2 glycosyl hydrolase K01195 E3.2.1.31; beta-glucuronidase [EC:3.2.1.31] D 3.2.1.32 endo-1,3-beta-xylanase D 3.2.1.33 amylo-alpha-1,6-glucosidase D 3.2.1.35 hyaluronoglucosaminidase D 3.2.1.36 hyaluronoglucuronidase D 3.2.1.37 xylan 1,4-beta-xylosidase D 3.2.1.38 beta-D-fucosidase D 3.2.1.39 glucan endo-1,3-beta-D-glucosidase D 3.2.1.40 alpha-L-rhamnosidase D 3.2.1.41 pullulanase E PRU_2749 pulA; pullulanase, type I K01200 E3.2.1.41; pullulanase [EC:3.2.1.41] D 3.2.1.42 GDP-glucosidase D 3.2.1.43 beta-L-rhamnosidase D 3.2.1.44 fucoidanase D 3.2.1.45 glucosylceramidase D 3.2.1.46 galactosylceramidase D 3.2.1.47 galactosylgalactosylglucosylceramidase D 3.2.1.48 sucrose alpha-glucosidase D 3.2.1.49 alpha-N-acetylgalactosaminidase D 3.2.1.50 alpha-N-acetylglucosaminidase D 3.2.1.51 alpha-L-fucosidase E PRU_1164 alpha-L-fucosidase family protein K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51] E PRU_1166 DS domain-containing protein K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51] E PRU_2780 family 29 glycosyl hydrolase K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51] E PRU_2729 hypothetical protein K15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51] D 3.2.1.52 beta-N-acetylhexosaminidase E PRU_0656 family 3 glycosyl hydrolase K01207 E3.2.1.52; beta-N-acetylhexosaminidase [EC:3.2.1.52] E PRU_1156 family 20 glycosyl hydrolase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] E PRU_1157 beta-N-acetylhexosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D 3.2.1.53 beta-N-acetylgalactosaminidase D 3.2.1.54 cyclomaltodextrinase D 3.2.1.55 alpha-N-arabinofuranosidase E PRU_0418 alpha-N-arabinofuranosidase K01209 E3.2.1.55; alpha-N-arabinofuranosidase [EC:3.2.1.55] D 3.2.1.56 glucuronosyl-disulfoglucosamine glucuronidase D 3.2.1.57 isopullulanase D 3.2.1.58 glucan 1,3-beta-glucosidase D 3.2.1.59 glucan endo-1,3-alpha-glucosidase D 3.2.1.60 glucan 1,4-alpha-maltotetraohydrolase D 3.2.1.61 mycodextranase D 3.2.1.62 glycosylceramidase D 3.2.1.63 1,2-alpha-L-fucosidase D 3.2.1.64 2,6-beta-fructan 6-levanbiohydrolase D 3.2.1.65 levanase E PRU_2276 fructan beta-(2 K01212 sacC; levanase [EC:3.2.1.65] D 3.2.1.66 quercitrinase D 3.2.1.67 galacturan 1,4-alpha-galacturonidase D 3.2.1.68 isoamylase D 3.2.1.70 glucan 1,6-alpha-glucosidase D 3.2.1.71 glucan endo-1,2-beta-glucosidase D 3.2.1.72 xylan 1,3-beta-xylosidase D 3.2.1.73 licheninase D 3.2.1.74 glucan 1,4-beta-glucosidase D 3.2.1.75 glucan endo-1,6-beta-glucosidase D 3.2.1.76 L-iduronidase D 3.2.1.77 mannan 1,2-(1,3)-alpha-mannosidase D 3.2.1.78 mannan endo-1,4-beta-mannosidase D 3.2.1.80 fructan beta-fructosidase D 3.2.1.81 beta-agarase D 3.2.1.82 exo-poly-alpha-galacturonosidase D 3.2.1.83 kappa-carrageenase D 3.2.1.84 glucan 1,3-alpha-glucosidase D 3.2.1.85 6-phospho-beta-galactosidase D 3.2.1.86 6-phospho-beta-glucosidase D 3.2.1.87 capsular-polysaccharide endo-1,3-alpha-galactosidase D 3.2.1.88 beta-L-arabinosidase D 3.2.1.89 arabinogalactan endo-beta-1,4-galactanase E PRU_1929 family 53 glycosyl hydrolase K01224 E3.2.1.89; arabinogalactan endo-1,4-beta-galactosidase [EC:3.2.1.89] E PRU_2676 family 53 glycosyl hydrolase K01224 E3.2.1.89; arabinogalactan endo-1,4-beta-galactosidase [EC:3.2.1.89] D 3.2.1.91 cellulose 1,4-beta-cellobiosidase (non-reducing end) D 3.2.1.92 peptidoglycan beta-N-acetylmuramidase D 3.2.1.93 alpha,alpha-phosphotrehalase D 3.2.1.94 glucan 1,6-alpha-isomaltosidase D 3.2.1.95 dextran 1,6-alpha-isomaltotriosidase D 3.2.1.96 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase D 3.2.1.97 endo-alpha-N-acetylgalactosaminidase D 3.2.1.98 glucan 1,4-alpha-maltohexaosidase D 3.2.1.99 arabinan endo-1,5-alpha-L-arabinanase E PRU_2673 arabinan endo-1 K06113 abnA; arabinan endo-1,5-alpha-L-arabinosidase [EC:3.2.1.99] D 3.2.1.100 mannan 1,4-mannobiosidase D 3.2.1.101 mannan endo-1,6-alpha-mannosidase D 3.2.1.102 blood-group-substance endo-1,4-beta-galactosidase D 3.2.1.103 keratan-sulfate endo-1,4-beta-galactosidase D 3.2.1.104 steryl-beta-glucosidase D 3.2.1.105 3alpha(S)-strictosidine beta-glucosidase D 3.2.1.106 mannosyl-oligosaccharide glucosidase D 3.2.1.107 protein-glucosylgalactosylhydroxylysine glucosidase D 3.2.1.108 lactase D 3.2.1.109 endogalactosaminidase D 3.2.1.111 1,3-alpha-L-fucosidase D 3.2.1.112 2-deoxyglucosidase D 3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase D 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase D 3.2.1.115 branched-dextran exo-1,2-alpha-glucosidase D 3.2.1.116 glucan 1,4-alpha-maltotriohydrolase D 3.2.1.117 amygdalin beta-glucosidase D 3.2.1.118 prunasin beta-glucosidase D 3.2.1.119 vicianin beta-glucosidase D 3.2.1.120 oligoxyloglucan beta-glycosidase D 3.2.1.121 polymannuronate hydrolase D 3.2.1.122 maltose-6'-phosphate glucosidase D 3.2.1.123 endoglycosylceramidase D 3.2.1.124 3-deoxy-2-octulosonidase D 3.2.1.125 raucaffricine beta-glucosidase D 3.2.1.126 coniferin beta-glucosidase D 3.2.1.127 1,6-alpha-L-fucosidase D 3.2.1.128 glycyrrhizin hydrolase D 3.2.1.129 endo-alpha-sialidase D 3.2.1.130 glycoprotein endo-alpha-1,2-mannosidase D 3.2.1.131 xylan alpha-1,2-glucuronosidase D 3.2.1.132 chitosanase D 3.2.1.133 glucan 1,4-alpha-maltohydrolase D 3.2.1.134 difructose-anhydride synthase D 3.2.1.135 neopullulanase D 3.2.1.136 glucuronoarabinoxylan endo-1,4-beta-xylanase D 3.2.1.137 mannan exo-1,2-1,6-alpha-mannosidase D 3.2.1.139 alpha-glucuronidase E PRU_0081 alpha-glucuronidase K01235 aguA; alpha-glucuronidase [EC:3.2.1.139] D 3.2.1.140 lacto-N-biosidase D 3.2.1.141 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase D 3.2.1.142 limit dextrinase D 3.2.1.143 poly(ADP-ribose) glycohydrolase D 3.2.1.144 3-deoxyoctulosonase D 3.2.1.145 galactan 1,3-beta-galactosidase D 3.2.1.146 beta-galactofuranosidase D 3.2.1.147 thioglucosidase D 3.2.1.149 beta-primeverosidase D 3.2.1.150 oligoxyloglucan reducing-end-specific cellobiohydrolase D 3.2.1.151 xyloglucan-specific endo-beta-1,4-glucanase D 3.2.1.152 mannosylglycoprotein endo-beta-mannosidase D 3.2.1.153 fructan beta-(2,1)-fructosidase D 3.2.1.154 fructan beta-(2,6)-fructosidase D 3.2.1.155 xyloglucan-specific exo-beta-1,4-glucanase D 3.2.1.156 oligosaccharide reducing-end xylanase E PRU_1268 family 8 glycosyl hydrolase K15531 rexA; oligosaccharide reducing-end xylanase [EC:3.2.1.156] D 3.2.1.157 iota-carrageenase D 3.2.1.158 alpha-agarase D 3.2.1.159 alpha-neoagaro-oligosaccharide hydrolase D 3.2.1.161 beta-apiosyl-beta-glucosidase D 3.2.1.162 lambda-carrageenase D 3.2.1.163 1,6-alpha-D-mannosidase D 3.2.1.164 galactan endo-1,6-beta-galactosidase D 3.2.1.165 exo-1,4-beta-D-glucosaminidase E PRU_0394 family 2 glycosyl hydrolase K15855 csxA; exo-1,4-beta-D-glucosaminidase [EC:3.2.1.165] D 3.2.1.166 heparanase D 3.2.1.167 baicalin-beta-D-glucuronidase D 3.2.1.168 hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase D 3.2.1.169 protein O-GlcNAcase D 3.2.1.170 mannosylglycerate hydrolase D 3.2.1.171 rhamnogalacturonan hydrolase D 3.2.1.172 unsaturated rhamnogalacturonyl hydrolase D 3.2.1.173 rhamnogalacturonan galacturonohydrolase D 3.2.1.174 rhamnogalacturonan rhamnohydrolase D 3.2.1.175 beta-D-glucopyranosyl abscisate beta-glucosidase D 3.2.1.176 cellulose 1,4-beta-cellobiosidase (reducing end) D 3.2.1.177 alpha-D-xyloside xylohydrolase E PRU_2232 alpha-glucosidase family protein K01811 yicI; alpha-D-xyloside xylohydrolase [EC:3.2.1.177] E PRU_1795 family 31 glycosyl hydrolase K01811 yicI; alpha-D-xyloside xylohydrolase [EC:3.2.1.177] E PRU_1865 alpha-xylosidase K01811 yicI; alpha-D-xyloside xylohydrolase [EC:3.2.1.177] D 3.2.1.178 beta-porphyranase D 3.2.1.179 gellan tetrasaccharide unsaturated glucuronyl hydrolase D 3.2.1.180 unsaturated chondroitin disaccharide hydrolase D 3.2.1.181 galactan endo-beta-1,3-galactanase D 3.2.1.182 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase D 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) D 3.2.1.184 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) D 3.2.1.- E PRU_0014 transglycosylase SLT/LysM domain-containing protein K08307 mltD; membrane-bound lytic murein transglycosylase D [EC:3.2.1.-] C 3.2.2 Hydrolysing N-glycosyl compounds D 3.2.2.1 purine nucleosidase D 3.2.2.2 inosine nucleosidase D 3.2.2.3 uridine nucleosidase D 3.2.2.4 AMP nucleosidase D 3.2.2.5 NAD+ nucleosidase D 3.2.2.6 NAD(P)+ nucleosidase D 3.2.2.7 adenosine nucleosidase D 3.2.2.8 ribosylpyrimidine nucleosidase D 3.2.2.9 adenosylhomocysteine nucleosidase E PRU_0126 MTA/SAH nucleosidase K01243 mtnN; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase [EC:3.2.2.9] D 3.2.2.10 pyrimidine-5'-nucleotide nucleosidase D 3.2.2.11 beta-aspartyl-N-acetylglucosaminidase D 3.2.2.12 inosinate nucleosidase D 3.2.2.13 1-methyladenosine nucleosidase D 3.2.2.14 NMN nucleosidase D 3.2.2.15 DNA-deoxyinosine glycosylase D 3.2.2.16 methylthioadenosine nucleosidase D 3.2.2.17 deoxyribodipyrimidine endonucleosidase D 3.2.2.19 [protein ADP-ribosylarginine] hydrolase D 3.2.2.20 DNA-3-methyladenine glycosylase I D 3.2.2.21 DNA-3-methyladenine glycosylase II D 3.2.2.22 rRNA N-glycosylase D 3.2.2.23 DNA-formamidopyrimidine glycosylase D 3.2.2.24 ADP-ribosyl-[dinitrogen reductase] hydrolase D 3.2.2.25 N-methyl nucleosidase D 3.2.2.26 futalosine hydrolase D 3.2.2.27 uracil-DNA glycosylase E PRU_2354 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D 3.2.2.28 double-stranded uracil-DNA glycosylase D 3.2.2.29 thymine-DNA glycosylase D 3.2.2.- E PRU_2000 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.-] C 3.2.- Glycosylases D 3.2.-.- B 3.3 Acting on ether bonds C 3.3.1 Thioether and trialkylsulfonium hydrolases D 3.3.1.1 adenosylhomocysteinase D 3.3.1.2 adenosylmethionine hydrolase C 3.3.2 Ether hydrolases D 3.3.2.1 isochorismatase D 3.3.2.2 alkenylglycerophosphocholine hydrolase D 3.3.2.4 trans-epoxysuccinate hydrolase D 3.3.2.5 alkenylglycerophosphoethanolamine hydrolase D 3.3.2.6 leukotriene-A4 hydrolase D 3.3.2.7 hepoxilin-epoxide hydrolase D 3.3.2.8 limonene-1,2-epoxide hydrolase D 3.3.2.9 microsomal epoxide hydrolase D 3.3.2.10 soluble epoxide hydrolase D 3.3.2.11 cholesterol-5,6-oxide hydrolase D 3.3.2.- B 3.4 Acting on peptide bonds (peptidases) C 3.4.11 Aminopeptidases D 3.4.11.1 leucyl aminopeptidase D 3.4.11.2 membrane alanyl aminopeptidase E PRU_2662 M1 family peptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] D 3.4.11.3 cystinyl aminopeptidase D 3.4.11.4 tripeptide aminopeptidase E PRU_0258 pepT; tripeptide aminopeptidase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D 3.4.11.5 prolyl aminopeptidase E PRU_1316 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D 3.4.11.6 aminopeptidase B D 3.4.11.7 glutamyl aminopeptidase D 3.4.11.9 Xaa-Pro aminopeptidase E PRU_2157 M24B subfamily peptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] E PRU_0557 M24B subfamily peptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D 3.4.11.10 bacterial leucyl aminopeptidase D 3.4.11.13 clostridial aminopeptidase D 3.4.11.14 cytosol alanyl aminopeptidase D 3.4.11.15 aminopeptidase Y D 3.4.11.16 Xaa-Trp aminopeptidase D 3.4.11.17 tryptophanyl aminopeptidase D 3.4.11.18 methionyl aminopeptidase E PRU_2094 map_2; methionine aminopeptidase, type I K01265 E3.4.11.18; methionyl aminopeptidase [EC:3.4.11.18] E PRU_0745 map_1; methionine aminopeptidase, type I K01265 E3.4.11.18; methionyl aminopeptidase [EC:3.4.11.18] D 3.4.11.19 D-stereospecific aminopeptidase D 3.4.11.20 aminopeptidase Ey D 3.4.11.21 aspartyl aminopeptidase D 3.4.11.22 aminopeptidase I D 3.4.11.23 PepB aminopeptidase D 3.4.11.24 aminopeptidase S D 3.4.11.25 beta-peptidyl aminopeptidase D 3.4.11.26 intermediate cleaving peptidase 55 D 3.4.11.- C 3.4.13 Dipeptidases D 3.4.13.4 Xaa-Arg dipeptidase D 3.4.13.5 Xaa-methyl-His dipeptidase D 3.4.13.7 Glu-Glu dipeptidase D 3.4.13.9 Xaa-Pro dipeptidase D 3.4.13.12 Met-Xaa dipeptidase D 3.4.13.17 non-stereospecific dipeptidase D 3.4.13.18 cytosol nonspecific dipeptidase D 3.4.13.19 membrane dipeptidase D 3.4.13.20 beta-Ala-His dipeptidase D 3.4.13.21 dipeptidase E D 3.4.13.22 D-Ala-D-Ala dipeptidase E PRU_1817 D-alanyl-D-alanine dipeptidase K08641 vanX; D-alanyl-D-alanine dipeptidase [EC:3.4.13.22] D 3.4.13.- E PRU_0766 pepD_1; Xaa-His dipeptidase K01270 K01270; dipeptidase D [EC:3.4.13.-] E PRU_1551 pepD_2; Xaa-His dipeptidase K01270 K01270; dipeptidase D [EC:3.4.13.-] C 3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases D 3.4.14.1 dipeptidyl-peptidase I D 3.4.14.2 dipeptidyl-peptidase II D 3.4.14.4 dipeptidyl-peptidase III E PRU_0989 M49 family peptidase K01277 E3.4.14.4; dipeptidyl-peptidase III [EC:3.4.14.4] D 3.4.14.5 dipeptidyl-peptidase IV E PRU_0634 dipeptidyl-peptidase IV K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] E PRU_1806 S9 family peptidase K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] D 3.4.14.6 dipeptidyl-dipeptidase D 3.4.14.9 tripeptidyl-peptidase I D 3.4.14.10 tripeptidyl-peptidase II D 3.4.14.11 Xaa-Pro dipeptidyl-peptidase D 3.4.14.12 Xaa-Xaa-Pro tripeptidyl-peptidase D 3.4.14.- C 3.4.15 Peptidyl-dipeptidases D 3.4.15.1 peptidyl-dipeptidase A D 3.4.15.4 peptidyl-dipeptidase B D 3.4.15.5 peptidyl-dipeptidase Dcp E PRU_0685 dcp; peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5] E PRU_0196 oligopeptidase A K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5] D 3.4.15.6 cyanophycinase C 3.4.16 Serine-type carboxypeptidases D 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase D 3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase E PRU_0828 serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] E PRU_1998 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] D 3.4.16.5 carboxypeptidase C D 3.4.16.6 carboxypeptidase D D 3.4.16.- C 3.4.17 Metallocarboxypeptidases D 3.4.17.1 carboxypeptidase A D 3.4.17.2 carboxypeptidase B D 3.4.17.3 lysine carboxypeptidase D 3.4.17.4 Gly-Xaa carboxypeptidase D 3.4.17.6 alanine carboxypeptidase D 3.4.17.8 muramoylpentapeptide carboxypeptidase D 3.4.17.10 carboxypeptidase E D 3.4.17.11 glutamate carboxypeptidase D 3.4.17.12 carboxypeptidase M D 3.4.17.13 muramoyltetrapeptide carboxypeptidase E PRU_2079 U61 family peptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] E PRU_2505 U61 family peptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] D 3.4.17.14 zinc D-Ala-D-Ala carboxypeptidase D 3.4.17.15 carboxypeptidase A2 D 3.4.17.16 membrane Pro-Xaa carboxypeptidase D 3.4.17.17 tubulinyl-Tyr carboxypeptidase D 3.4.17.18 carboxypeptidase T D 3.4.17.19 carboxypeptidase Taq D 3.4.17.20 carboxypeptidase U D 3.4.17.21 glutamate carboxypeptidase II D 3.4.17.22 metallocarboxypeptidase D D 3.4.17.23 angiotensin-converting enzyme 2 D 3.4.17.- C 3.4.18 Cysteine-type carboxypeptidases D 3.4.18.1 cathepsin X C 3.4.19 Omega peptidases D 3.4.19.1 acylaminoacyl-peptidase D 3.4.19.2 peptidyl-glycinamidase D 3.4.19.3 pyroglutamyl-peptidase I D 3.4.19.5 beta-aspartyl-peptidase D 3.4.19.6 pyroglutamyl-peptidase II D 3.4.19.7 N-formylmethionyl-peptidase D 3.4.19.9 gamma-glutamyl hydrolase D 3.4.19.11 gamma-D-glutamyl-meso-diaminopimelate peptidase D 3.4.19.12 ubiquitinyl hydrolase 1 D 3.4.19.13 glutathione hydrolase D 3.4.19.14 leukotriene-C4 hydrolase D 3.4.19.- C 3.4.21 Serine endopeptidases D 3.4.21.1 chymotrypsin D 3.4.21.2 chymotrypsin C D 3.4.21.3 metridin D 3.4.21.4 trypsin D 3.4.21.5 thrombin D 3.4.21.6 coagulation factor Xa D 3.4.21.7 plasmin D 3.4.21.9 enteropeptidase D 3.4.21.10 acrosin D 3.4.21.12 alpha-lytic endopeptidase D 3.4.21.19 glutamyl endopeptidase D 3.4.21.20 cathepsin G D 3.4.21.21 coagulation factor VIIa D 3.4.21.22 coagulation factor IXa D 3.4.21.25 cucumisin D 3.4.21.26 prolyl oligopeptidase D 3.4.21.27 coagulation factor XIa D 3.4.21.32 brachyurin D 3.4.21.34 plasma kallikrein D 3.4.21.35 tissue kallikrein D 3.4.21.36 pancreatic elastase D 3.4.21.37 leukocyte elastase D 3.4.21.38 coagulation factor XIIa D 3.4.21.39 chymase D 3.4.21.41 complement subcomponent C_overbar_1r_ D 3.4.21.42 complement subcomponent C_overbar_1s_ D 3.4.21.43 classical-complement-pathway C3/C5 convertase D 3.4.21.45 complement factor I D 3.4.21.46 complement factor D D 3.4.21.47 alternative-complement-pathway C3/C5 convertase D 3.4.21.48 cerevisin D 3.4.21.49 hypodermin C D 3.4.21.50 lysyl endopeptidase D 3.4.21.53 endopeptidase La E PRU_0842 lon; endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D 3.4.21.54 gamma-renin D 3.4.21.55 venombin AB D 3.4.21.57 leucyl endopeptidase D 3.4.21.59 tryptase D 3.4.21.60 scutelarin D 3.4.21.61 kexin D 3.4.21.62 subtilisin D 3.4.21.63 oryzin D 3.4.21.64 peptidase K D 3.4.21.65 thermomycolin D 3.4.21.66 thermitase D 3.4.21.67 endopeptidase So D 3.4.21.68 t-plasminogen activator D 3.4.21.69 protein C (activated) D 3.4.21.70 pancreatic endopeptidase E D 3.4.21.71 pancreatic elastase II D 3.4.21.72 IgA-specific serine endopeptidase D 3.4.21.73 u-plasminogen activator D 3.4.21.74 venombin A D 3.4.21.75 furin D 3.4.21.76 myeloblastin D 3.4.21.77 semenogelase D 3.4.21.78 granzyme A D 3.4.21.79 granzyme B D 3.4.21.80 streptogrisin A D 3.4.21.81 streptogrisin B D 3.4.21.82 glutamyl endopeptidase II D 3.4.21.83 oligopeptidase B D 3.4.21.84 limulus clotting factor _overbar_C_ D 3.4.21.85 limulus clotting factor _overbar_B_ D 3.4.21.86 limulus clotting enzyme D 3.4.21.88 repressor LexA D 3.4.21.89 signal peptidase I E PRU_2448 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D 3.4.21.90 togavirin D 3.4.21.91 flavivirin D 3.4.21.92 endopeptidase Clp E PRU_0029 clpP; ATP-dependent Clp protease proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D 3.4.21.93 proprotein convertase 1 D 3.4.21.94 proprotein convertase 2 D 3.4.21.95 snake venom factor V activator D 3.4.21.96 lactocepin D 3.4.21.97 assemblin D 3.4.21.98 hepacivirin D 3.4.21.99 spermosin D 3.4.21.100 sedolisin D 3.4.21.101 xanthomonalisin D 3.4.21.102 C-terminal processing peptidase E PRU_2368 S41 family peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] E PRU_2476 S41 family peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] E PRU_0198 S41 family peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D 3.4.21.103 physarolisin D 3.4.21.104 mannan-binding lectin-associated serine protease-2 D 3.4.21.105 rhomboid protease D 3.4.21.106 hepsin D 3.4.21.107 peptidase Do D 3.4.21.108 HtrA2 peptidase D 3.4.21.109 matriptase D 3.4.21.110 C5a peptidase D 3.4.21.111 aqualysin 1 D 3.4.21.112 site-1 protease D 3.4.21.113 pestivirus NS3 polyprotein peptidase D 3.4.21.114 equine arterivirus serine peptidase D 3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase D 3.4.21.116 SpoIVB peptidase D 3.4.21.117 stratum corneum chymotryptic enzyme D 3.4.21.118 kallikrein 8 D 3.4.21.119 kallikrein 13 D 3.4.21.120 oviductin D 3.4.21.- E PRU_0924 umuD_1; prophage PRU01 UmuD protein K03503 DPO5D; DNA polymerase V [EC:3.4.21.-] E PRU_1185 umuD_2; UmuD protein K03503 DPO5D; DNA polymerase V [EC:3.4.21.-] E PRU_0308 sppA; signal peptide peptidase SppA, 67K type K04773 sppA; protease IV [EC:3.4.21.-] E PRU_1998 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] C 3.4.22 Cysteine endopeptidases D 3.4.22.1 cathepsin B D 3.4.22.2 papain D 3.4.22.3 ficain D 3.4.22.6 chymopapain D 3.4.22.7 asclepain D 3.4.22.8 clostripain D 3.4.22.10 streptopain D 3.4.22.14 actinidain D 3.4.22.15 cathepsin L D 3.4.22.16 cathepsin H D 3.4.22.24 cathepsin T D 3.4.22.25 glycyl endopeptidase D 3.4.22.26 cancer procoagulant D 3.4.22.27 cathepsin S D 3.4.22.28 picornain 3C D 3.4.22.29 picornain 2A D 3.4.22.30 caricain D 3.4.22.31 ananain D 3.4.22.32 stem bromelain D 3.4.22.33 fruit bromelain D 3.4.22.34 legumain D 3.4.22.35 histolysain D 3.4.22.36 caspase-1 D 3.4.22.37 gingipain R D 3.4.22.38 cathepsin K D 3.4.22.39 adenain D 3.4.22.40 bleomycin hydrolase E PRU_0548 pepC; bleomycin hydrolase K01372 E3.4.22.40; bleomycin hydrolase [EC:3.4.22.40] D 3.4.22.41 cathepsin F D 3.4.22.42 cathepsin O D 3.4.22.43 cathepsin V D 3.4.22.44 nuclear-inclusion-a endopeptidase D 3.4.22.45 helper-component proteinase D 3.4.22.46 L-peptidase D 3.4.22.47 gingipain K D 3.4.22.48 staphopain D 3.4.22.49 separase D 3.4.22.50 V-cath endopeptidase D 3.4.22.51 cruzipain D 3.4.22.52 calpain-1 D 3.4.22.53 calpain-2 D 3.4.22.54 calpain-3 D 3.4.22.55 caspase-2 D 3.4.22.56 caspase-3 D 3.4.22.57 caspase-4 D 3.4.22.58 caspase-5 D 3.4.22.59 caspase-6 D 3.4.22.60 caspase-7 D 3.4.22.61 caspase-8 D 3.4.22.62 caspase-9 D 3.4.22.63 caspase-10 D 3.4.22.64 caspase-11 D 3.4.22.65 peptidase 1 (mite) D 3.4.22.66 calicivirin D 3.4.22.67 zingipain D 3.4.22.68 Ulp1 peptidase D 3.4.22.69 SARS coronavirus main proteinase D 3.4.22.70 sortase A D 3.4.22.71 sortase B D 3.4.22.- C 3.4.23 Aspartic endopeptidases D 3.4.23.1 pepsin A D 3.4.23.2 pepsin B D 3.4.23.3 gastricsin D 3.4.23.4 chymosin D 3.4.23.5 cathepsin D D 3.4.23.12 nepenthesin D 3.4.23.15 renin D 3.4.23.16 HIV-1 retropepsin D 3.4.23.17 pro-opiomelanocortin converting enzyme D 3.4.23.18 aspergillopepsin I D 3.4.23.19 aspergillopepsin II D 3.4.23.20 penicillopepsin D 3.4.23.21 rhizopuspepsin D 3.4.23.22 endothiapepsin D 3.4.23.23 mucorpepsin D 3.4.23.24 candidapepsin D 3.4.23.25 saccharopepsin D 3.4.23.26 rhodotorulapepsin D 3.4.23.28 acrocylindropepsin D 3.4.23.29 polyporopepsin D 3.4.23.30 pycnoporopepsin D 3.4.23.31 scytalidopepsin A D 3.4.23.32 scytalidopepsin B D 3.4.23.34 cathepsin E D 3.4.23.35 barrierpepsin D 3.4.23.36 signal peptidase II E PRU_1067 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] D 3.4.23.38 plasmepsin I D 3.4.23.39 plasmepsin II D 3.4.23.40 phytepsin D 3.4.23.41 yapsin 1 D 3.4.23.42 thermopsin D 3.4.23.43 prepilin peptidase D 3.4.23.44 nodavirus endopeptidase D 3.4.23.45 memapsin 1 D 3.4.23.46 memapsin 2 D 3.4.23.47 HIV-2 retropepsin D 3.4.23.48 plasminogen activator Pla D 3.4.23.49 omptin D 3.4.23.50 human endogenous retrovirus K endopeptidase D 3.4.23.51 HycI peptidase D 3.4.23.52 preflagellin peptidase D 3.4.23.- C 3.4.24 Metalloendopeptidases D 3.4.24.1 atrolysin A D 3.4.24.3 microbial collagenase D 3.4.24.6 leucolysin D 3.4.24.7 interstitial collagenase D 3.4.24.11 neprilysin D 3.4.24.12 envelysin D 3.4.24.13 IgA-specific metalloendopeptidase D 3.4.24.14 procollagen N-endopeptidase D 3.4.24.15 thimet oligopeptidase D 3.4.24.16 neurolysin D 3.4.24.17 stromelysin 1 D 3.4.24.18 meprin A D 3.4.24.19 procollagen C-endopeptidase D 3.4.24.20 peptidyl-Lys metalloendopeptidase D 3.4.24.21 astacin D 3.4.24.22 stromelysin 2 D 3.4.24.23 matrilysin D 3.4.24.24 gelatinase A D 3.4.24.25 vibriolysin D 3.4.24.26 pseudolysin D 3.4.24.27 thermolysin D 3.4.24.28 bacillolysin D 3.4.24.29 aureolysin D 3.4.24.30 coccolysin D 3.4.24.31 mycolysin D 3.4.24.32 beta-lytic metalloendopeptidase D 3.4.24.33 peptidyl-Asp metalloendopeptidase D 3.4.24.34 neutrophil collagenase D 3.4.24.35 gelatinase B D 3.4.24.36 leishmanolysin D 3.4.24.37 saccharolysin D 3.4.24.38 gametolysin D 3.4.24.39 deuterolysin D 3.4.24.40 serralysin D 3.4.24.41 atrolysin B D 3.4.24.42 atrolysin C D 3.4.24.43 atroxase D 3.4.24.44 atrolysin E D 3.4.24.45 atrolysin F D 3.4.24.46 adamalysin D 3.4.24.47 horrilysin D 3.4.24.48 ruberlysin D 3.4.24.49 bothropasin D 3.4.24.50 bothrolysin D 3.4.24.51 ophiolysin D 3.4.24.52 trimerelysin I D 3.4.24.53 trimerelysin II D 3.4.24.54 mucrolysin D 3.4.24.55 pitrilysin D 3.4.24.56 insulysin D 3.4.24.57 O-sialoglycoprotein endopeptidase E PRU_0746 gcp; O-sialoglycoprotein endopeptidase K01409 gcp; O-sialoglycoprotein endopeptidase [EC:3.4.24.57] D 3.4.24.58 russellysin D 3.4.24.59 mitochondrial intermediate peptidase D 3.4.24.60 dactylysin D 3.4.24.61 nardilysin D 3.4.24.62 magnolysin D 3.4.24.63 meprin B D 3.4.24.64 mitochondrial processing peptidase D 3.4.24.65 macrophage elastase D 3.4.24.66 choriolysin L D 3.4.24.67 choriolysin H D 3.4.24.68 tentoxilysin D 3.4.24.69 bontoxilysin D 3.4.24.70 oligopeptidase A D 3.4.24.71 endothelin-converting enzyme 1 D 3.4.24.72 fibrolase D 3.4.24.73 jararhagin D 3.4.24.74 fragilysin D 3.4.24.75 lysostaphin D 3.4.24.76 flavastacin D 3.4.24.77 snapalysin D 3.4.24.78 gpr endopeptidase D 3.4.24.79 pappalysin-1 D 3.4.24.80 membrane-type matrix metalloproteinase-1 D 3.4.24.81 ADAM10 endopeptidase D 3.4.24.82 ADAMTS-4 endopeptidase D 3.4.24.83 anthrax lethal factor endopeptidase D 3.4.24.84 Ste24 endopeptidase D 3.4.24.85 S2P endopeptidase D 3.4.24.86 ADAM 17 endopeptidase D 3.4.24.87 ADAMTS13 endopeptidase D 3.4.24.- E PRU_0044 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] E PRU_2293 M16 family peptidase K07263 pqqL; zinc protease [EC:3.4.24.-] E PRU_0603 pepO_1; endopeptidase PepO K07386 pepO; putative endopeptidase [EC:3.4.24.-] E PRU_2924 membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] C 3.4.25 Threonine endopeptidases D 3.4.25.1 proteasome endopeptidase complex D 3.4.25.2 HslU---HslV peptidase D 3.4.25.- C 3.4.99 Endopeptidases of unknown catalytic mechanism D 3.4.99.- C 3.4.- Acting on peptide bonds (peptidases) D 3.4.-.- E PRU_0638 penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.1.- 3.4.-.-] E PRU_0704 penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.1.- 3.4.-.-] E PRU_0610 U32 family peptidase K08303 K08303; putative protease [EC:3.4.-.-] E PRU_2846 prtC; collagenase K08303 K08303; putative protease [EC:3.4.-.-] B 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds C 3.5.1 In linear amides D 3.5.1.1 asparaginase D 3.5.1.2 glutaminase E PRU_0658 glutaminase K01425 glsA; glutaminase [EC:3.5.1.2] D 3.5.1.3 omega-amidase D 3.5.1.4 amidase D 3.5.1.5 urease D 3.5.1.6 beta-ureidopropionase D 3.5.1.7 ureidosuccinase D 3.5.1.8 formylaspartate deformylase D 3.5.1.9 arylformamidase D 3.5.1.10 formyltetrahydrofolate deformylase E PRU_0486 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D 3.5.1.11 penicillin amidase D 3.5.1.12 biotinidase D 3.5.1.13 aryl-acylamidase D 3.5.1.14 aminoacylase D 3.5.1.15 aspartoacylase D 3.5.1.16 acetylornithine deacetylase E PRU_2920 acetylornithine deacetylase K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] D 3.5.1.17 acyl-lysine deacylase D 3.5.1.18 succinyl-diaminopimelate desuccinylase D 3.5.1.19 nicotinamidase D 3.5.1.20 citrullinase D 3.5.1.21 N-acetyl-beta-alanine deacetylase D 3.5.1.22 pantothenase D 3.5.1.23 ceramidase D 3.5.1.24 choloylglycine hydrolase D 3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase D 3.5.1.26 N4-(beta-N-acetylglucosaminyl)-L-asparaginase D 3.5.1.27 N-formylmethionylaminoacyl-tRNA deformylase D 3.5.1.28 N-acetylmuramoyl-L-alanine amidase E PRU_1285 N-acetylmuramoyl-L-alanine amidase K01448 E3.5.1.28B; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D 3.5.1.29 2-(acetamidomethylene)succinate hydrolase D 3.5.1.30 5-aminopentanamidase D 3.5.1.31 formylmethionine deformylase D 3.5.1.32 hippurate hydrolase D 3.5.1.33 N-acetylglucosamine deacetylase D 3.5.1.35 D-glutaminase D 3.5.1.36 N-methyl-2-oxoglutaramate hydrolase D 3.5.1.38 glutamin-(asparagin-)ase D 3.5.1.39 alkylamidase D 3.5.1.40 acylagmatine amidase D 3.5.1.41 chitin deacetylase D 3.5.1.42 nicotinamide-nucleotide amidase D 3.5.1.43 peptidyl-glutaminase D 3.5.1.44 protein-glutamine glutaminase D 3.5.1.46 6-aminohexanoate-dimer hydrolase D 3.5.1.47 N-acetyldiaminopimelate deacetylase D 3.5.1.48 acetylspermidine deacetylase D 3.5.1.49 formamidase D 3.5.1.50 pentanamidase D 3.5.1.51 4-acetamidobutyryl-CoA deacetylase D 3.5.1.52 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase D 3.5.1.53 N-carbamoylputrescine amidase E PRU_1417 carbon-nitrogen family hydrolase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53] D 3.5.1.54 allophanate hydrolase D 3.5.1.55 long-chain-fatty-acyl-glutamate deacylase D 3.5.1.56 N,N-dimethylformamidase D 3.5.1.57 tryptophanamidase D 3.5.1.58 N-benzyloxycarbonylglycine hydrolase D 3.5.1.59 N-carbamoylsarcosine amidase D 3.5.1.60 N-(long-chain-acyl)ethanolamine deacylase D 3.5.1.61 mimosinase D 3.5.1.62 acetylputrescine deacetylase D 3.5.1.63 4-acetamidobutyrate deacetylase D 3.5.1.64 Nalpha-benzyloxycarbonylleucine hydrolase D 3.5.1.65 theanine hydrolase D 3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase D 3.5.1.67 4-methyleneglutaminase D 3.5.1.68 N-formylglutamate deformylase D 3.5.1.69 glycosphingolipid deacylase D 3.5.1.70 aculeacin-A deacylase D 3.5.1.71 N-feruloylglycine deacylase D 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase D 3.5.1.73 carnitinamidase D 3.5.1.74 chenodeoxycholoyltaurine hydrolase D 3.5.1.75 urethanase D 3.5.1.76 arylalkyl acylamidase D 3.5.1.77 N-carbamoyl-D-amino-acid hydrolase D 3.5.1.78 glutathionylspermidine amidase D 3.5.1.79 phthalyl amidase D 3.5.1.81 N-acyl-D-amino-acid deacylase D 3.5.1.82 N-acyl-D-glutamate deacylase D 3.5.1.83 N-acyl-D-aspartate deacylase D 3.5.1.84 biuret amidohydrolase D 3.5.1.85 (S)-N-acetyl-1-phenylethylamine hydrolase D 3.5.1.86 mandelamide amidase D 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase D 3.5.1.88 peptide deformylase E PRU_0591 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D 3.5.1.89 N-acetylglucosaminylphosphatidylinositol deacetylase D 3.5.1.90 adenosylcobinamide hydrolase D 3.5.1.91 N-substituted formamide deformylase D 3.5.1.92 pantetheine hydrolase D 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase D 3.5.1.94 gamma-glutamyl-gamma-aminobutyrate hydrolase D 3.5.1.95 N-malonylurea hydrolase D 3.5.1.96 succinylglutamate desuccinylase D 3.5.1.97 acyl-homoserine-lactone acylase D 3.5.1.98 histone deacetylase D 3.5.1.99 fatty acid amide hydrolase D 3.5.1.100 (R)-amidase D 3.5.1.101 L-proline amide hydrolase D 3.5.1.102 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase D 3.5.1.103 N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase D 3.5.1.104 peptidoglycan-N-acetylglucosamine deacetylase D 3.5.1.105 chitin disaccharide deacetylase D 3.5.1.106 N-formylmaleamate deformylase D 3.5.1.107 maleamate amidohydrolase D 3.5.1.108 UDP-3-O-acyl-N-acetylglucosamine deacetylase E PRU_0707 UDP-3-0-acyl N-acetylglucosamine deacetylase/beta-hydroxyacyl-(acyl-carrier-protein) dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59] D 3.5.1.109 sphingomyelin deacylase D 3.5.1.110 peroxyureidoacrylate/ureidoacrylate amidohydrolase D 3.5.1.111 2-oxoglutaramate amidase D 3.5.1.112 2'-N-acetylparomamine deacetylase D 3.5.1.113 2'''-acetyl-6'''-hydroxyneomycin C deacetylase D 3.5.1.- E PRU_2859 npdA; NAD-dependent deacetylase K12410 npdA; NAD-dependent deacetylase [EC:3.5.1.-] C 3.5.2 In cyclic amides D 3.5.2.1 barbiturase D 3.5.2.2 dihydropyrimidinase D 3.5.2.3 dihydroorotase E PRU_1614 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3] D 3.5.2.4 carboxymethylhydantoinase D 3.5.2.5 allantoinase D 3.5.2.6 beta-lactamase D 3.5.2.7 imidazolonepropionase D 3.5.2.9 5-oxoprolinase (ATP-hydrolysing) D 3.5.2.10 creatininase D 3.5.2.11 L-lysine-lactamase D 3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase D 3.5.2.13 2,5-dioxopiperazine hydrolase D 3.5.2.14 N-methylhydantoinase (ATP-hydrolysing) D 3.5.2.15 cyanuric acid amidohydrolase D 3.5.2.16 maleimide hydrolase D 3.5.2.17 hydroxyisourate hydrolase D 3.5.2.18 enamidase D 3.5.2.19 streptothricin hydrolase D 3.5.2.- C 3.5.3 In linear amidines D 3.5.3.1 arginase D 3.5.3.2 guanidinoacetase D 3.5.3.3 creatinase D 3.5.3.4 allantoicase D 3.5.3.5 formimidoylaspartate deiminase D 3.5.3.6 arginine deiminase D 3.5.3.7 guanidinobutyrase D 3.5.3.8 formimidoylglutamase D 3.5.3.9 allantoate deiminase D 3.5.3.10 D-arginase D 3.5.3.11 agmatinase D 3.5.3.12 agmatine deiminase D 3.5.3.13 formimidoylglutamate deiminase D 3.5.3.14 amidinoaspartase D 3.5.3.15 protein-arginine deiminase D 3.5.3.16 methylguanidinase D 3.5.3.17 guanidinopropionase D 3.5.3.18 dimethylargininase D 3.5.3.19 ureidoglycolate hydrolase D 3.5.3.20 diguanidinobutanase D 3.5.3.21 methylenediurea deaminase D 3.5.3.22 proclavaminate amidinohydrolase D 3.5.3.23 N-succinylarginine dihydrolase D 3.5.3.- C 3.5.4 In cyclic amidines D 3.5.4.1 cytosine deaminase D 3.5.4.2 adenine deaminase D 3.5.4.3 guanine deaminase D 3.5.4.4 adenosine deaminase D 3.5.4.5 cytidine deaminase E PRU_0980 cytidine deaminase K01489 E3.5.4.5; cytidine deaminase [EC:3.5.4.5] D 3.5.4.6 AMP deaminase D 3.5.4.7 ADP deaminase D 3.5.4.8 aminoimidazolase D 3.5.4.9 methenyltetrahydrofolate cyclohydrolase E PRU_1152 folD; bifunctional protein FolD K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D 3.5.4.10 IMP cyclohydrolase E PRU_1709 IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] E PRU_1927 phosphoribosylaminoimidazolecarboxamide formyltransferase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D 3.5.4.11 pterin deaminase D 3.5.4.12 dCMP deaminase E PRU_0197 cytidine/deoxycytidylate deaminase zinc-binding domain-containing protein K01493 comEB; dCMP deaminase [EC:3.5.4.12] D 3.5.4.13 dCTP deaminase D 3.5.4.14 deoxycytidine deaminase D 3.5.4.15 guanosine deaminase D 3.5.4.16 GTP cyclohydrolase I E PRU_1862 folE; GTP cyclohydrolase I K01495 folE; GTP cyclohydrolase I [EC:3.5.4.16] D 3.5.4.17 adenosine-phosphate deaminase D 3.5.4.18 ATP deaminase D 3.5.4.19 phosphoribosyl-AMP cyclohydrolase E PRU_0482 hisIE; phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase K11755 hisIE; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase [EC:3.6.1.31 3.5.4.19] D 3.5.4.20 pyrithiamine deaminase D 3.5.4.21 creatinine deaminase D 3.5.4.22 1-pyrroline-4-hydroxy-2-carboxylate deaminase D 3.5.4.23 blasticidin-S deaminase D 3.5.4.24 sepiapterin deaminase D 3.5.4.25 GTP cyclohydrolase II E PRU_1913 ribBA; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D 3.5.4.26 diaminohydroxyphosphoribosylaminopyrimidine deaminase E PRU_2399 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D 3.5.4.27 methenyltetrahydromethanopterin cyclohydrolase D 3.5.4.28 S-adenosylhomocysteine deaminase D 3.5.4.29 GTP cyclohydrolase IIa D 3.5.4.30 dCTP deaminase (dUMP-forming) D 3.5.4.31 S-methyl-5'-thioadenosine deaminase D 3.5.4.32 8-oxoguanine deaminase D 3.5.4.33 tRNA(adenine34) deaminase D 3.5.4.34 tRNAAla(adenine37) deaminase D 3.5.4.35 tRNA(cytosine8) deaminase D 3.5.4.36 mRNA(cytosine6666) deaminase D 3.5.4.- C 3.5.5 In nitriles D 3.5.5.1 nitrilase D 3.5.5.2 ricinine nitrilase D 3.5.5.4 cyanoalanine nitrilase D 3.5.5.5 arylacetonitrilase D 3.5.5.6 bromoxynil nitrilase D 3.5.5.7 aliphatic nitrilase D 3.5.5.8 thiocyanate hydrolase D 3.5.5.- C 3.5.99 In other compounds D 3.5.99.1 riboflavinase D 3.5.99.2 aminopyrimidine aminohydrolase D 3.5.99.3 hydroxydechloroatrazine ethylaminohydrolase D 3.5.99.4 N-isopropylammelide isopropylaminohydrolase D 3.5.99.5 2-aminomuconate deaminase D 3.5.99.6 glucosamine-6-phosphate deaminase E PRU_1155 dehydrogenase domain-containing protein K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] E PRU_0116 nagB; glucosamine-6-phosphate deaminase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D 3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase D 3.5.99.8 5-nitroanthranilic acid aminohydrolase D 3.5.99.9 2-nitroimidazole nitrohydrolase D 3.5.99.- C 3.5.- Acting on carbon-nitrogen bonds, other than peptide bonds D 3.5.-.- B 3.6 Acting on acid anhydrides C 3.6.1 In phosphorus-containing anhydrides D 3.6.1.1 inorganic diphosphatase E PRU_0830 V-type H(+)-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:3.6.1.1] D 3.6.1.2 trimetaphosphatase D 3.6.1.3 adenosinetriphosphatase D 3.6.1.5 apyrase D 3.6.1.6 nucleoside diphosphate phosphatase D 3.6.1.7 acylphosphatase D 3.6.1.8 ATP diphosphatase D 3.6.1.9 nucleotide diphosphatase D 3.6.1.10 endopolyphosphatase D 3.6.1.11 exopolyphosphatase D 3.6.1.12 dCTP diphosphatase D 3.6.1.13 ADP-ribose diphosphatase D 3.6.1.14 adenosine-tetraphosphatase D 3.6.1.15 nucleoside-triphosphate phosphatase D 3.6.1.16 CDP-glycerol diphosphatase D 3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) D 3.6.1.18 FAD diphosphatase D 3.6.1.19 nucleoside-triphosphate diphosphatase E PRU_2528 non-canonical purine NTP pyrophosphatase K02428 rdgB; dITP/XTP pyrophosphatase [EC:3.6.1.19] E PRU_1413 MazG family protein K02428 rdgB; dITP/XTP pyrophosphatase [EC:3.6.1.19] D 3.6.1.20 5'-acylphosphoadenosine hydrolase D 3.6.1.21 ADP-sugar diphosphatase D 3.6.1.22 NAD+ diphosphatase E PRU_1311 NUDIX family hydrolase K03426 E3.6.1.22; NAD+ diphosphatase [EC:3.6.1.22] D 3.6.1.23 dUTP diphosphatase E PRU_2916 dut; dUTP diphosphatase K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23] D 3.6.1.24 nucleoside phosphoacylhydrolase D 3.6.1.25 triphosphatase D 3.6.1.26 CDP-diacylglycerol diphosphatase D 3.6.1.27 undecaprenyl-diphosphate phosphatase E PRU_1833 undecaprenol kinase K06153 E3.6.1.27; undecaprenyl-diphosphatase [EC:3.6.1.27] D 3.6.1.28 thiamine-triphosphatase D 3.6.1.29 bis(5'-adenosyl)-triphosphatase D 3.6.1.31 phosphoribosyl-ATP diphosphatase E PRU_0482 hisIE; phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase K11755 hisIE; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase [EC:3.6.1.31 3.5.4.19] D 3.6.1.39 thymidine-triphosphatase D 3.6.1.40 guanosine-5'-triphosphate,3'-diphosphate phosphatase D 3.6.1.41 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) D 3.6.1.42 guanosine-diphosphatase D 3.6.1.43 dolichyldiphosphatase D 3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase D 3.6.1.45 UDP-sugar diphosphatase D 3.6.1.52 diphosphoinositol-polyphosphate diphosphatase D 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase D 3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase E PRU_2253 LpxH family protein K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D 3.6.1.55 8-oxo-dGTP diphosphatase D 3.6.1.56 2-hydroxy-dATP diphosphatase D 3.6.1.57 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase D 3.6.1.58 8-oxo-dGDP phosphatase D 3.6.1.59 m7GpppX diphosphatase D 3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming) D 3.6.1.61 diadenosine hexaphosphate hydrolase (ATP-forming) D 3.6.1.62 m7GpppN-mRNA hydrolase D 3.6.1.63 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase D 3.6.1.64 inosine diphosphate phosphatase D 3.6.1.- E PRU_0662 mutT_1; mutator mutT protein K03574 MUTT; 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] E PRU_0340 nudF; ADP-ribose pyrophosphatase K03574 MUTT; 7,8-dihydro-8-oxoguanine triphosphatase [EC:3.6.1.-] E PRU_0075 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase [EC:3.6.1.-] C 3.6.2 In sulfonyl-containing anhydrides D 3.6.2.1 adenylylsulfatase D 3.6.2.2 phosphoadenylylsulfatase C 3.6.3 Acting on acid anhydrides to catalyse transmembrane movement of substances D 3.6.3.1 phospholipid-translocating ATPase D 3.6.3.2 Mg2+-importing ATPase D 3.6.3.3 Cd2+-exporting ATPase E PRU_0260 cadA; cadmium-exporting ATPase K01534 zntA; Cd2+/Zn2+-exporting ATPase [EC:3.6.3.3 3.6.3.5] D 3.6.3.4 Cu2+-exporting ATPase D 3.6.3.5 Zn2+-exporting ATPase E PRU_0260 cadA; cadmium-exporting ATPase K01534 zntA; Cd2+/Zn2+-exporting ATPase [EC:3.6.3.3 3.6.3.5] D 3.6.3.6 H+-exporting ATPase D 3.6.3.7 Na+-exporting ATPase D 3.6.3.8 Ca2+-transporting ATPase E PRU_2007 calcium-translocating P-type ATPase K01537 E3.6.3.8; Ca2+-transporting ATPase [EC:3.6.3.8] D 3.6.3.9 Na+/K+-exchanging ATPase D 3.6.3.10 H+/K+-exchanging ATPase D 3.6.3.11 Cl--transporting ATPase D 3.6.3.12 K+-transporting ATPase D 3.6.3.14 H+-transporting two-sector ATPase E PRU_1196 atpB; ATP synthase F0 subunit A K02108 ATPF0A; F-type H+-transporting ATPase subunit a [EC:3.6.3.14] E PRU_1194 atpF; ATP synthase F0 subunit B K02109 ATPF0B; F-type H+-transporting ATPase subunit b [EC:3.6.3.14] E PRU_1195 atpE; ATP synthase F0 subunit C K02110 ATPF0C; F-type H+-transporting ATPase subunit c [EC:3.6.3.14] E PRU_1192 atpA; ATP synthase F1 subunit alpha K02111 ATPF1A; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14] E PRU_1199 atpD; ATP synthase F1 subunit beta K02112 ATPF1B; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] E PRU_1193 atpH; ATP synthase F1 subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta [EC:3.6.3.14] E PRU_1198 ATP synthase F1 subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14] E PRU_1191 atpG; ATP synthase F1 subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma [EC:3.6.3.14] D 3.6.3.15 Na+-transporting two-sector ATPase D 3.6.3.16 arsenite-transporting ATPase D 3.6.3.17 monosaccharide-transporting ATPase D 3.6.3.18 oligosaccharide-transporting ATPase D 3.6.3.19 maltose-transporting ATPase D 3.6.3.20 glycerol-3-phosphate-transporting ATPase D 3.6.3.21 polar-amino-acid-transporting ATPase E PRU_1636 amino acid ABC transporter ATP-binding protein/permease K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21] D 3.6.3.22 nonpolar-amino-acid-transporting ATPase D 3.6.3.23 oligopeptide-transporting ATPase D 3.6.3.24 nickel-transporting ATPase D 3.6.3.25 sulfate-transporting ATPase D 3.6.3.26 nitrate-transporting ATPase D 3.6.3.27 phosphate-transporting ATPase D 3.6.3.28 phosphonate-transporting ATPase D 3.6.3.29 molybdate-transporting ATPase D 3.6.3.30 Fe3+-transporting ATPase D 3.6.3.31 polyamine-transporting ATPase D 3.6.3.32 quaternary-amine-transporting ATPase D 3.6.3.33 vitamin B12-transporting ATPase D 3.6.3.34 iron-chelate-transporting ATPase E PRU_2512 iron compound ABC transporter ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34] D 3.6.3.35 manganese-transporting ATPase D 3.6.3.36 taurine-transporting ATPase D 3.6.3.37 guanine-transporting ATPase D 3.6.3.38 capsular-polysaccharide-transporting ATPase D 3.6.3.39 lipopolysaccharide-transporting ATPase D 3.6.3.40 teichoic-acid-transporting ATPase D 3.6.3.41 heme-transporting ATPase D 3.6.3.42 beta-glucan-transporting ATPase D 3.6.3.43 peptide-transporting ATPase D 3.6.3.44 xenobiotic-transporting ATPase D 3.6.3.46 cadmium-transporting ATPase D 3.6.3.47 fatty-acyl-CoA-transporting ATPase D 3.6.3.48 alpha-factor-transporting ATPase D 3.6.3.49 channel-conductance-controlling ATPase D 3.6.3.50 protein-secreting ATPase D 3.6.3.51 mitochondrial protein-transporting ATPase D 3.6.3.52 chloroplast protein-transporting ATPase D 3.6.3.53 Ag+-exporting ATPase D 3.6.3.- E PRU_0756 hypothetical protein K03924 moxR; MoxR-like ATPase [EC:3.6.3.-] E PRU_0027 ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-] E PRU_0052 ABC transporter ATP-binding protein K09810 ABC.LPT.A; lipoprotein-releasing system ATP-binding protein [EC:3.6.3.-] E PRU_2913 msbA; lipid A export permease/ATP-binding protein K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:3.6.3.-] C 3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement D 3.6.4.1 myosin ATPase D 3.6.4.2 dynein ATPase D 3.6.4.3 microtubule-severing ATPase D 3.6.4.4 plus-end-directed kinesin ATPase D 3.6.4.5 minus-end-directed kinesin ATPase D 3.6.4.6 vesicle-fusing ATPase D 3.6.4.7 peroxisome-assembly ATPase D 3.6.4.8 proteasome ATPase D 3.6.4.9 chaperonin ATPase D 3.6.4.10 non-chaperonin molecular chaperone ATPase D 3.6.4.11 nucleoplasmin ATPase D 3.6.4.12 DNA helicase E PRU_0834 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:3.6.4.12] E PRU_2041 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12] E PRU_2468 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12] E PRU_0554 RecQ family ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:3.6.4.12] E PRU_0991 recQ_2; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:3.6.4.12] E PRU_0031 recQ_1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:3.6.4.12] E PRU_1944 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12] E PRU_0995 ATP-dependent DNA helicase PcrA K03657 uvrD; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12] D 3.6.4.13 RNA helicase E PRU_2639 DEAD/DEAH box helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:3.6.4.13] D 3.6.4.- E PRU_1607 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-] E PRU_2170 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:3.6.4.-] C 3.6.5 Acting on GTP to facilitate cellular and subcellular movement D 3.6.5.1 heterotrimeric G-protein GTPase D 3.6.5.2 small monomeric GTPase D 3.6.5.3 protein-synthesizing GTPase D 3.6.5.4 signal-recognition-particle GTPase D 3.6.5.5 dynamin GTPase D 3.6.5.6 tubulin GTPase D 3.6.5.- C 3.6.- Acting on acid anhydrides D 3.6.-.- E PRU_0695 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-] B 3.7 Acting on carbon-carbon bonds C 3.7.1 In ketonic substances D 3.7.1.1 oxaloacetase D 3.7.1.2 fumarylacetoacetase D 3.7.1.3 kynureninase D 3.7.1.4 phloretin hydrolase D 3.7.1.5 acylpyruvate hydrolase D 3.7.1.6 acetylpyruvate hydrolase D 3.7.1.7 beta-diketone hydrolase D 3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase D 3.7.1.9 2-hydroxymuconate-semialdehyde hydrolase D 3.7.1.10 cyclohexane-1,3-dione hydrolase D 3.7.1.11 cyclohexane-1,2-dione hydrolase D 3.7.1.12 cobalt-precorrin 5A hydrolase D 3.7.1.13 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase D 3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase D 3.7.1.15 (+)-caryolan-1-ol synthase D 3.7.1.16 oxepin-CoA hydrolase D 3.7.1.17 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase D 3.7.1.18 6-oxocamphor hydrolase D 3.7.1.19 2,6-dihydroxypseudooxynicotine hydrolase D 3.7.1.20 3-fumarylpyruvate hydrolase D 3.7.1.- B 3.8 Acting on halide bonds C 3.8.1 In carbon-halide compounds D 3.8.1.1 alkylhalidase D 3.8.1.2 (S)-2-haloacid dehalogenase D 3.8.1.3 haloacetate dehalogenase D 3.8.1.5 haloalkane dehalogenase D 3.8.1.6 4-chlorobenzoate dehalogenase D 3.8.1.7 4-chlorobenzoyl-CoA dehalogenase D 3.8.1.8 atrazine chlorohydrolase D 3.8.1.9 (R)-2-haloacid dehalogenase D 3.8.1.10 2-haloacid dehalogenase (configuration-inverting) D 3.8.1.11 2-haloacid dehalogenase (configuration-retaining) D 3.8.1.- B 3.9 Acting on phosphorus-nitrogen bonds C 3.9.1 Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date) D 3.9.1.1 phosphoamidase B 3.10 Acting on sulfur-nitrogen bonds C 3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date) D 3.10.1.1 N-sulfoglucosamine sulfohydrolase D 3.10.1.2 cyclamate sulfohydrolase B 3.11 Acting on carbon-phosphorus bonds C 3.11.1 Acting on carbon-phosphorus bonds (only sub-subclass identified to date) D 3.11.1.1 phosphonoacetaldehyde hydrolase D 3.11.1.2 phosphonoacetate hydrolase D 3.11.1.3 phosphonopyruvate hydrolase B 3.12 Acting on sulfur-sulfur bonds C 3.12.1 Acting on sulfur-sulfur bonds (only sub-subclass identified to date) D 3.12.1.1 trithionate hydrolase B 3.13 Acting on carbon-sulfur bonds C 3.13.1 Acting on carbon-sulfur bonds (only sub-subclass identified to date) D 3.13.1.1 UDP-sulfoquinovose synthase D 3.13.1.3 2'-hydroxybiphenyl-2-sulfinate desulfinase B 3.- C 3.-.- D 3.-.-.- # A4. Lyases B 4.1 Carbon-carbon lyases C 4.1.1 Carboxy-lyases D 4.1.1.1 pyruvate decarboxylase D 4.1.1.2 oxalate decarboxylase D 4.1.1.3 oxaloacetate decarboxylase E PRU_1644 sodium ion-translocating decarboxylase subunit beta K01572 E4.1.1.3B; oxaloacetate decarboxylase, beta subunit [EC:4.1.1.3] D 4.1.1.4 acetoacetate decarboxylase D 4.1.1.5 acetolactate decarboxylase D 4.1.1.6 aconitate decarboxylase D 4.1.1.7 benzoylformate decarboxylase D 4.1.1.8 oxalyl-CoA decarboxylase D 4.1.1.9 malonyl-CoA decarboxylase D 4.1.1.11 aspartate 1-decarboxylase E PRU_2452 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D 4.1.1.12 aspartate 4-decarboxylase D 4.1.1.14 valine decarboxylase D 4.1.1.15 glutamate decarboxylase D 4.1.1.16 hydroxyglutamate decarboxylase D 4.1.1.17 ornithine decarboxylase D 4.1.1.18 lysine decarboxylase D 4.1.1.19 arginine decarboxylase E PRU_2625 speA; arginine 2-monooxygenase K01585 E4.1.1.19S; arginine decarboxylase [EC:4.1.1.19] D 4.1.1.20 diaminopimelate decarboxylase E PRU_0479 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D 4.1.1.21 phosphoribosylaminoimidazole carboxylase D 4.1.1.22 histidine decarboxylase D 4.1.1.23 orotidine-5'-phosphate decarboxylase E PRU_0710 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D 4.1.1.24 aminobenzoate decarboxylase D 4.1.1.25 tyrosine decarboxylase D 4.1.1.28 aromatic-L-amino-acid decarboxylase D 4.1.1.29 sulfinoalanine decarboxylase D 4.1.1.30 pantothenoylcysteine decarboxylase D 4.1.1.31 phosphoenolpyruvate carboxylase D 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP) D 4.1.1.33 diphosphomevalonate decarboxylase D 4.1.1.34 dehydro-L-gulonate decarboxylase D 4.1.1.35 UDP-glucuronate decarboxylase D 4.1.1.36 phosphopantothenoylcysteine decarboxylase E PRU_2453 coaBC; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase [EC:4.1.1.36 6.3.2.5] D 4.1.1.37 uroporphyrinogen decarboxylase E PRU_2550 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D 4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate) D 4.1.1.39 ribulose-bisphosphate carboxylase D 4.1.1.40 hydroxypyruvate decarboxylase D 4.1.1.41 methylmalonyl-CoA decarboxylase D 4.1.1.42 carnitine decarboxylase D 4.1.1.43 phenylpyruvate decarboxylase D 4.1.1.44 4-carboxymuconolactone decarboxylase D 4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase D 4.1.1.46 o-pyrocatechuate decarboxylase D 4.1.1.47 tartronate-semialdehyde synthase D 4.1.1.48 indole-3-glycerol-phosphate synthase E PRU_1458 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48] D 4.1.1.49 phosphoenolpyruvate carboxykinase (ATP) E PRU_2279 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 E4.1.1.49; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D 4.1.1.50 adenosylmethionine decarboxylase D 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase D 4.1.1.52 6-methylsalicylate decarboxylase D 4.1.1.53 phenylalanine decarboxylase D 4.1.1.54 dihydroxyfumarate decarboxylase D 4.1.1.55 4,5-dihydroxyphthalate decarboxylase D 4.1.1.56 3-oxolaurate decarboxylase D 4.1.1.57 methionine decarboxylase D 4.1.1.58 orsellinate decarboxylase D 4.1.1.59 gallate decarboxylase D 4.1.1.60 stipitatonate decarboxylase D 4.1.1.61 4-hydroxybenzoate decarboxylase D 4.1.1.62 gentisate decarboxylase D 4.1.1.63 protocatechuate decarboxylase D 4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate) D 4.1.1.65 phosphatidylserine decarboxylase E PRU_1895 psd; phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D 4.1.1.66 uracil-5-carboxylate decarboxylase D 4.1.1.67 UDP-galacturonate decarboxylase D 4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase D 4.1.1.69 3,4-dihydroxyphthalate decarboxylase D 4.1.1.70 glutaconyl-CoA decarboxylase D 4.1.1.71 2-oxoglutarate decarboxylase D 4.1.1.72 branched-chain-2-oxoacid decarboxylase D 4.1.1.73 tartrate decarboxylase D 4.1.1.74 indolepyruvate decarboxylase D 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase D 4.1.1.76 arylmalonate decarboxylase D 4.1.1.77 2-oxo-3-hexenedioate decarboxylase D 4.1.1.78 acetylenedicarboxylate decarboxylase D 4.1.1.79 sulfopyruvate decarboxylase D 4.1.1.80 4-hydroxyphenylpyruvate decarboxylase D 4.1.1.81 threonine-phosphate decarboxylase E PRU_2511 class I/II aminotransferase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81] D 4.1.1.82 phosphonopyruvate decarboxylase D 4.1.1.83 4-hydroxyphenylacetate decarboxylase D 4.1.1.84 D-dopachrome decarboxylase D 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase D 4.1.1.86 diaminobutyrate decarboxylase D 4.1.1.87 malonyl-S-ACP decarboxylase D 4.1.1.88 biotin-independent malonate decarboxylase D 4.1.1.89 biotin-dependent malonate decarboxylase D 4.1.1.90 peptidyl-glutamate 4-carboxylase D 4.1.1.91 salicylate decarboxylase D 4.1.1.92 indole-3-carboxylate decarboxylase D 4.1.1.93 pyrrole-2-carboxylate decarboxylase D 4.1.1.94 ethylmalonyl-CoA decarboxylase D 4.1.1.95 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase D 4.1.1.96 carboxynorspermidine decarboxylase D 4.1.1.- E PRU_0887 nspC; carboxynorspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.-] C 4.1.2 Aldehyde-lyases D 4.1.2.2 ketotetrose-phosphate aldolase D 4.1.2.4 deoxyribose-phosphate aldolase E PRU_2483 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D 4.1.2.5 L-threonine aldolase E PRU_2214 L-threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.5] D 4.1.2.8 indole-3-glycerol-phosphate lyase D 4.1.2.9 phosphoketolase D 4.1.2.10 (R)-mandelonitrile lyase D 4.1.2.11 hydroxymandelonitrile lyase D 4.1.2.12 2-dehydropantoate aldolase D 4.1.2.13 fructose-bisphosphate aldolase E PRU_2062 fba; fructose-1,6-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase E PRU_0872 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16] D 4.1.2.17 L-fuculose-phosphate aldolase D 4.1.2.18 2-dehydro-3-deoxy-L-pentonate aldolase D 4.1.2.19 rhamnulose-1-phosphate aldolase E PRU_1465 rhaD; rhamnulose-1-phosphate aldolase K01629 rhaD; rhamnulose-1-phosphate aldolase [EC:4.1.2.19] D 4.1.2.20 2-dehydro-3-deoxyglucarate aldolase D 4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase D 4.1.2.22 fructose-6-phosphate phosphoketolase D 4.1.2.23 3-deoxy-D-manno-octulosonate aldolase D 4.1.2.24 dimethylaniline-N-oxide aldolase D 4.1.2.25 dihydroneopterin aldolase E PRU_1286 folB; dihydroneopterin aldolase K01633 folB; dihydroneopterin aldolase [EC:4.1.2.25] D 4.1.2.26 phenylserine aldolase D 4.1.2.27 sphinganine-1-phosphate aldolase D 4.1.2.28 2-dehydro-3-deoxy-D-pentonate aldolase D 4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase D 4.1.2.30 17alpha-hydroxyprogesterone aldolase D 4.1.2.32 trimethylamine-oxide aldolase D 4.1.2.33 fucosterol-epoxide lyase D 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase D 4.1.2.35 propioin synthase D 4.1.2.36 lactate aldolase D 4.1.2.38 benzoin aldolase D 4.1.2.40 tagatose-bisphosphate aldolase D 4.1.2.41 vanillin synthase D 4.1.2.42 D-threonine aldolase D 4.1.2.43 3-hexulose-6-phosphate synthase D 4.1.2.44 benzoyl-CoA-dihydrodiol lyase D 4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase D 4.1.2.46 aliphatic (R)-hydroxynitrile lyase D 4.1.2.47 (S)-hydroxynitrile lyase D 4.1.2.48 low-specificity L-threonine aldolase D 4.1.2.49 L-allo-threonine aldolase D 4.1.2.50 6-carboxytetrahydropterin synthase D 4.1.2.- C 4.1.3 Oxo-acid-lyases D 4.1.3.1 isocitrate lyase D 4.1.3.3 N-acetylneuraminate lyase D 4.1.3.4 hydroxymethylglutaryl-CoA lyase D 4.1.3.6 citrate (pro-3S)-lyase D 4.1.3.13 oxalomalate lyase D 4.1.3.14 L-erythro-3-hydroxyaspartate aldolase D 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase E PRU_0872 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16] D 4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase D 4.1.3.22 citramalate lyase D 4.1.3.24 malyl-CoA lyase D 4.1.3.25 citramalyl-CoA lyase D 4.1.3.26 3-hydroxy-3-isohexenylglutaryl-CoA lyase D 4.1.3.27 anthranilate synthase E PRU_1455 trpE; anthranilate synthase subunit I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] E PRU_1456 trpG; anthranilate synthase subunit II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D 4.1.3.30 methylisocitrate lyase D 4.1.3.32 2,3-dimethylmalate lyase D 4.1.3.34 citryl-CoA lyase D 4.1.3.35 (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase D 4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase E PRU_1684 menB; naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36] D 4.1.3.38 aminodeoxychorismate lyase D 4.1.3.39 4-hydroxy-2-oxovalerate aldolase D 4.1.3.40 chorismate lyase D 4.1.3.41 3-hydroxy-D-aspartate aldolase D 4.1.3.42 (4S)-4-hydroxy-2-oxoglutarate aldolase D 4.1.3.- E PRU_0483 hisF; imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; cyclase [EC:4.1.3.-] C 4.1.99 Other carbon-carbon lyases D 4.1.99.1 tryptophanase D 4.1.99.2 tyrosine phenol-lyase D 4.1.99.3 deoxyribodipyrimidine photo-lyase D 4.1.99.5 octadecanal decarbonylase D 4.1.99.11 benzylsuccinate synthase D 4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase E PRU_1913 ribBA; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] D 4.1.99.13 (6-4)DNA photolyase D 4.1.99.14 spore photoproduct lyase D 4.1.99.16 geosmin synthase D 4.1.99.17 phosphomethylpyrimidine synthase D 4.1.99.18 cyclic pyranopterin phosphate synthase D 4.1.99.19 2-iminoacetate synthase D 4.1.99.- C 4.1.- Carbon-carbon lyases D 4.1.-.- B 4.2 Carbon-oxygen lyases C 4.2.1 Hydro-lyases D 4.2.1.1 carbonate dehydratase D 4.2.1.2 fumarate hydratase E PRU_0119 fumarate hydratase K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2] D 4.2.1.3 aconitate hydratase D 4.2.1.4 citrate dehydratase D 4.2.1.5 arabinonate dehydratase D 4.2.1.6 galactonate dehydratase D 4.2.1.7 altronate dehydratase E PRU_0875 uxaA; altronate dehydratase K01685 uxaA; altronate hydrolase [EC:4.2.1.7] D 4.2.1.8 mannonate dehydratase E PRU_0736 uxuA; mannonate dehydratase K01686 uxuA; mannonate dehydratase [EC:4.2.1.8] D 4.2.1.9 dihydroxy-acid dehydratase E PRU_1078 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D 4.2.1.10 3-dehydroquinate dehydratase E PRU_2289 aroQ; 3-dehydroquinate dehydratase, type II K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D 4.2.1.11 phosphopyruvate hydratase E PRU_1102 eno; phosphopyruvate hydratase K01689 ENO; enolase [EC:4.2.1.11] D 4.2.1.12 phosphogluconate dehydratase D 4.2.1.17 enoyl-CoA hydratase D 4.2.1.18 methylglutaconyl-CoA hydratase D 4.2.1.19 imidazoleglycerol-phosphate dehydratase E PRU_0455 hisB; histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase K01089 hisB; imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] D 4.2.1.20 tryptophan synthase E PRU_1460 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] E PRU_1454 trpB; tryptophan synthase subunit beta K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] E PRU_1351 pyridoxal-phosphate dependent TrpB-like protein K06001 K06001; tryptophan synthase beta chain [EC:4.2.1.20] D 4.2.1.22 cystathionine beta-synthase D 4.2.1.24 porphobilinogen synthase D 4.2.1.25 L-arabinonate dehydratase D 4.2.1.27 acetylenecarboxylate hydratase D 4.2.1.28 propanediol dehydratase D 4.2.1.30 glycerol dehydratase D 4.2.1.31 maleate hydratase D 4.2.1.32 L(+)-tartrate dehydratase D 4.2.1.33 3-isopropylmalate dehydratase E PRU_0730 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] E PRU_0731 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D 4.2.1.34 (S)-2-methylmalate dehydratase D 4.2.1.35 (R)-2-methylmalate dehydratase E PRU_0730 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] E PRU_0731 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D 4.2.1.36 homoaconitate hydratase D 4.2.1.39 gluconate dehydratase D 4.2.1.40 glucarate dehydratase D 4.2.1.41 5-dehydro-4-deoxyglucarate dehydratase D 4.2.1.42 galactarate dehydratase D 4.2.1.43 2-dehydro-3-deoxy-L-arabinonate dehydratase D 4.2.1.44 myo-inosose-2 dehydratase D 4.2.1.45 CDP-glucose 4,6-dehydratase E PRU_0435 CDP-D-glucose-4 K01709 rfbG; CDP-glucose 4,6-dehydratase [EC:4.2.1.45] D 4.2.1.46 dTDP-glucose 4,6-dehydratase E PRU_0173 rfbB; dTDP-glucose 4,6-dehydratase K01710 E4.2.1.46; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D 4.2.1.47 GDP-mannose 4,6-dehydratase E PRU_1377 gmd; GDP-mannose 4,6-dehydratase K01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47] D 4.2.1.48 D-glutamate cyclase D 4.2.1.49 urocanate hydratase D 4.2.1.50 pyrazolylalanine synthase D 4.2.1.51 prephenate dehydratase E PRU_0284 pheC; cyclohexadienyl dehydratase K01713 pheC; cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91] E PRU_1174 prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51] D 4.2.1.53 oleate hydratase D 4.2.1.54 lactoyl-CoA dehydratase D 4.2.1.55 3-hydroxybutyryl-CoA dehydratase D 4.2.1.56 itaconyl-CoA hydratase D 4.2.1.57 isohexenylglutaconyl-CoA hydratase D 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase E PRU_0707 UDP-3-0-acyl N-acetylglucosamine deacetylase/beta-hydroxyacyl-(acyl-carrier-protein) dehydratase K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59] D 4.2.1.62 5alpha-hydroxysteroid dehydratase D 4.2.1.65 3-cyanoalanine hydratase D 4.2.1.66 cyanide hydratase D 4.2.1.67 D-fuconate dehydratase D 4.2.1.68 L-fuconate dehydratase D 4.2.1.69 cyanamide hydratase D 4.2.1.70 pseudouridylate synthase D 4.2.1.73 protoaphin-aglucone dehydratase (cyclizing) D 4.2.1.74 long-chain-enoyl-CoA hydratase D 4.2.1.75 uroporphyrinogen-III synthase E PRU_2553 hypothetical protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] E PRU_2296 hemD; uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D 4.2.1.76 UDP-glucose 4,6-dehydratase D 4.2.1.77 trans-L-3-hydroxyproline dehydratase D 4.2.1.78 (S)-norcoclaurine synthase D 4.2.1.79 2-methylcitrate dehydratase D 4.2.1.80 2-oxopent-4-enoate hydratase D 4.2.1.81 D(-)-tartrate dehydratase D 4.2.1.82 xylonate dehydratase D 4.2.1.83 4-oxalomesaconate hydratase D 4.2.1.84 nitrile hydratase D 4.2.1.85 dimethylmaleate hydratase D 4.2.1.87 octopamine dehydratase D 4.2.1.88 synephrine dehydratase D 4.2.1.89 carnitine dehydratase D 4.2.1.90 L-rhamnonate dehydratase D 4.2.1.91 arogenate dehydratase E PRU_0284 pheC; cyclohexadienyl dehydratase K01713 pheC; cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91] D 4.2.1.92 hydroperoxide dehydratase D 4.2.1.93 ATP-dependent NAD(P)H-hydrate dehydratase D 4.2.1.94 scytalone dehydratase D 4.2.1.95 kievitone hydratase D 4.2.1.96 4a-hydroxytetrahydrobiopterin dehydratase D 4.2.1.97 phaseollidin hydratase D 4.2.1.98 16alpha-hydroxyprogesterone dehydratase D 4.2.1.99 2-methylisocitrate dehydratase D 4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase D 4.2.1.101 trans-feruloyl-CoA hydratase D 4.2.1.103 cyclohexyl-isocyanide hydratase D 4.2.1.104 cyanase D 4.2.1.105 2-hydroxyisoflavanone dehydratase D 4.2.1.106 bile-acid 7alpha-dehydratase D 4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase D 4.2.1.108 ectoine synthase D 4.2.1.109 methylthioribulose 1-phosphate dehydratase D 4.2.1.110 aldos-2-ulose dehydratase D 4.2.1.111 1,5-anhydro-D-fructose dehydratase D 4.2.1.112 acetylene hydratase D 4.2.1.113 o-succinylbenzoate synthase D 4.2.1.114 methanogen homoaconitase D 4.2.1.115 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) D 4.2.1.116 3-hydroxypropionyl-CoA dehydratase D 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) D 4.2.1.118 3-dehydroshikimate dehydratase D 4.2.1.119 enoyl-CoA hydratase 2 D 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase D 4.2.1.121 colneleate synthase D 4.2.1.122 tryptophan synthase (indole-salvaging) D 4.2.1.123 tetrahymanol synthase D 4.2.1.124 arabidiol synthase D 4.2.1.125 dammarenediol II synthase D 4.2.1.126 N-acetylmuramic acid 6-phosphate etherase E PRU_2383 murQ; N-acetylmuramic acid 6-phosphate etherase K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126] D 4.2.1.127 linalool dehydratase D 4.2.1.128 lupan-3beta,20-diol synthase D 4.2.1.129 squalene---hopanol cyclase D 4.2.1.130 D-lactate dehydratase D 4.2.1.131 carotenoid 1,2-hydratase D 4.2.1.132 2-hydroxyhexa-2,4-dienoate hydratase D 4.2.1.133 copal-8-ol diphosphate hydratase D 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase D 4.2.1.135 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) D 4.2.1.136 ADP-dependent NAD(P)H-hydrate dehydratase D 4.2.1.137 sporulenol synthase D 4.2.1.- C 4.2.2 Acting on polysaccharides D 4.2.2.1 hyaluronate lyase D 4.2.2.2 pectate lyase D 4.2.2.3 poly(beta-D-mannuronate) lyase D 4.2.2.5 chondroitin AC lyase D 4.2.2.6 oligogalacturonide lyase D 4.2.2.7 heparin lyase D 4.2.2.8 heparin-sulfate lyase D 4.2.2.9 pectate disaccharide-lyase D 4.2.2.10 pectin lyase D 4.2.2.11 poly(alpha-L-guluronate) lyase D 4.2.2.12 xanthan lyase D 4.2.2.13 exo-(1->4)-alpha-D-glucan lyase D 4.2.2.14 glucuronan lyase D 4.2.2.15 anhydrosialidase D 4.2.2.16 levan fructotransferase (DFA-IV-forming) D 4.2.2.17 inulin fructotransferase (DFA-I-forming) D 4.2.2.18 inulin fructotransferase (DFA-III-forming) D 4.2.2.19 chondroitin B lyase D 4.2.2.20 chondroitin-sulfate-ABC endolyase D 4.2.2.21 chondroitin-sulfate-ABC exolyase D 4.2.2.22 pectate trisaccharide-lyase D 4.2.2.23 rhamnogalacturonan endolyase D 4.2.2.24 rhamnogalacturonan exolyase D 4.2.2.25 gellan lyase D 4.2.2.- C 4.2.3 Acting on phosphates D 4.2.3.1 threonine synthase E PRU_1018 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D 4.2.3.2 ethanolamine-phosphate phospho-lyase D 4.2.3.3 methylglyoxal synthase D 4.2.3.4 3-dehydroquinate synthase E PRU_1681 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D 4.2.3.5 chorismate synthase E PRU_0544 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D 4.2.3.6 trichodiene synthase D 4.2.3.7 pentalenene synthase D 4.2.3.8 casbene synthase D 4.2.3.9 aristolochene synthase D 4.2.3.10 (-)-endo-fenchol synthase D 4.2.3.11 sabinene-hydrate synthase D 4.2.3.12 6-pyruvoyltetrahydropterin synthase D 4.2.3.13 (+)-delta-cadinene synthase D 4.2.3.15 myrcene synthase D 4.2.3.16 (4S)-limonene synthase D 4.2.3.17 taxadiene synthase D 4.2.3.18 abieta-7,13-diene synthase D 4.2.3.19 ent-kaurene synthase D 4.2.3.20 (R)-limonene synthase D 4.2.3.21 vetispiradiene synthase D 4.2.3.22 germacradienol synthase D 4.2.3.23 germacrene-A synthase D 4.2.3.24 amorpha-4,11-diene synthase D 4.2.3.25 S-linalool synthase D 4.2.3.26 R-linalool synthase D 4.2.3.27 isoprene synthase D 4.2.3.28 ent-cassa-12,15-diene synthase D 4.2.3.29 ent-sandaracopimaradiene synthase D 4.2.3.30 ent-pimara-8(14),15-diene synthase D 4.2.3.31 ent-pimara-9(11),15-diene synthase D 4.2.3.32 levopimaradiene synthase D 4.2.3.33 stemar-13-ene synthase D 4.2.3.34 stemod-13(17)-ene synthase D 4.2.3.35 syn-pimara-7,15-diene synthase D 4.2.3.36 terpentetriene synthase D 4.2.3.37 epi-isozizaene synthase D 4.2.3.38 alpha-bisabolene synthase D 4.2.3.39 epi-cedrol synthase D 4.2.3.40 (Z)-gamma-bisabolene synthase D 4.2.3.41 elisabethatriene synthase D 4.2.3.42 aphidicolan-16beta-ol synthase D 4.2.3.43 fusicocca-2,10(14)-diene synthase D 4.2.3.44 isopimara-7,15-diene synthase D 4.2.3.45 phyllocladan-16alpha-ol synthase D 4.2.3.46 alpha-farnesene synthase D 4.2.3.47 beta-farnesene synthase D 4.2.3.48 (3S,6E)-nerolidol synthase D 4.2.3.49 (3R,6E)-nerolidol synthase D 4.2.3.50 (+)-alpha-santalene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.51 beta-phellandrene synthase (neryl-diphosphate-cyclizing) D 4.2.3.52 (4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) D 4.2.3.53 (+)-endo-beta-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.54 (-)-endo-alpha-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.55 (S)-beta-bisabolene synthase D 4.2.3.56 gamma-humulene synthase D 4.2.3.57 (-)-beta-caryophyllene synthase D 4.2.3.58 longifolene synthase D 4.2.3.59 (E)-gamma-bisabolene synthase D 4.2.3.60 germacrene C synthase D 4.2.3.61 5-epiaristolochene synthase D 4.2.3.62 (-)-gamma-cadinene synthase [(2Z,6E)-farnesyl diphosphate cyclizing] D 4.2.3.63 (+)-cubenene synthase D 4.2.3.64 (+)-epicubenol synthase D 4.2.3.65 zingiberene synthase D 4.2.3.66 beta-selinene cyclase D 4.2.3.67 cis-muuroladiene synthase D 4.2.3.68 beta-eudesmol synthase D 4.2.3.69 (+)-alpha-barbatene synthase D 4.2.3.70 patchoulol synthase D 4.2.3.71 (E,E)-germacrene B synthase D 4.2.3.72 alpha-gurjunene synthase D 4.2.3.73 valencene synthase D 4.2.3.74 presilphiperfolanol synthase D 4.2.3.75 (-)-germacrene D synthase D 4.2.3.76 (+)-delta-selinene synthase D 4.2.3.77 (+)-germacrene D synthase D 4.2.3.78 beta-chamigrene synthase D 4.2.3.79 thujopsene synthase D 4.2.3.80 alpha-longipinene synthase D 4.2.3.81 exo-alpha-bergamotene synthase D 4.2.3.82 alpha-santalene synthase D 4.2.3.83 beta-santalene synthase D 4.2.3.84 10-epi-gamma-eudesmol synthase D 4.2.3.85 alpha-eudesmol synthase D 4.2.3.86 7-epi-alpha-selinene synthase D 4.2.3.87 alpha-guaiene synthase D 4.2.3.88 viridiflorene synthase D 4.2.3.89 (+)-beta-caryophyllene synthase D 4.2.3.90 5-epi-alpha-selinene synthase D 4.2.3.91 cubebol synthase D 4.2.3.92 (+)-gamma-cadinene synthase D 4.2.3.93 delta-guaiene synthase D 4.2.3.94 gamma-curcumene synthase D 4.2.3.95 (-)-alpha-cuprenene synthase D 4.2.3.96 avermitilol synthase D 4.2.3.97 (-)-delta-cadinene synthase D 4.2.3.98 (+)-T-muurolol synthase D 4.2.3.99 labdatriene synthase D 4.2.3.100 bicyclogermacrene synthase D 4.2.3.101 7-epi-sesquithujene synthase D 4.2.3.102 sesquithujene synthase D 4.2.3.103 ent-isokaurene synthase D 4.2.3.104 alpha-humulene synthase D 4.2.3.105 tricyclene synthase D 4.2.3.106 (E)-beta-ocimene synthase D 4.2.3.107 (+)-car-3-ene synthase D 4.2.3.108 1,8-cineole synthase D 4.2.3.109 (-)-sabinene synthase D 4.2.3.110 (+)-sabinene synthase D 4.2.3.111 (-)-alpha-terpineol synthase D 4.2.3.112 (+)-alpha-terpineol synthase D 4.2.3.113 terpinolene synthase D 4.2.3.114 gamma-terpinene synthase D 4.2.3.115 alpha-terpinene synthase D 4.2.3.116 (+)-camphene synthase D 4.2.3.117 (-)-camphene synthase D 4.2.3.118 2-methylisoborneol synthase D 4.2.3.119 (-)-alpha-pinene synthase D 4.2.3.120 (-)-beta-pinene synthase D 4.2.3.121 (+)-alpha-pinene synthase D 4.2.3.122 (+)-beta-pinene synthase D 4.2.3.123 beta-sesquiphellandrene synthase D 4.2.3.124 2-deoxy-scyllo-inosose synthase D 4.2.3.125 alpha-muurolene synthase D 4.2.3.126 gamma-muurolene synthase D 4.2.3.127 beta-copaene synthase D 4.2.3.128 beta-cubebene synthase D 4.2.3.129 (+)-sativene synthase D 4.2.3.130 tetraprenyl-beta-curcumene synthase D 4.2.3.131 miltiradiene synthase D 4.2.3.132 neoabietadiene synthase D 4.2.3.133 alpha-copaene synthase D 4.2.3.134 5-phosphonooxy-L-lysine phospho-lyase D 4.2.3.135 Delta6-protoilludene synthase D 4.2.3.136 alpha-isocomene synthase D 4.2.3.137 (E)-2-epi-beta-caryophyllene synthase D 4.2.3.138 (+)-epi-alpha-bisabolol synthase D 4.2.3.139 valerena-4,7(11)-diene synthase D 4.2.3.140 cis-abienol synthase D 4.2.3.141 sclareol synthase D 4.2.3.142 7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.- C 4.2.99 Other carbon-oxygen lyases D 4.2.99.12 carboxymethyloxysuccinate lyase D 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase E PRU_1406 nth; endonuclease III K10773 NTH; endonuclease III [EC:4.2.99.18] D 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase D 4.2.99.21 isochorismate lyase D 4.2.99.- C 4.2.- Carbon-oxygen lyases D 4.2.-.- B 4.3 Carbon-nitrogen lyases C 4.3.1 Ammonia-lyases D 4.3.1.1 aspartate ammonia-lyase D 4.3.1.2 methylaspartate ammonia-lyase D 4.3.1.3 histidine ammonia-lyase D 4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase D 4.3.1.6 beta-alanyl-CoA ammonia-lyase D 4.3.1.7 ethanolamine ammonia-lyase D 4.3.1.9 glucosaminate ammonia-lyase D 4.3.1.10 serine-sulfate ammonia-lyase D 4.3.1.12 ornithine cyclodeaminase D 4.3.1.13 carbamoyl-serine ammonia-lyase D 4.3.1.14 3-aminobutyryl-CoA ammonia-lyase D 4.3.1.15 diaminopropionate ammonia-lyase D 4.3.1.16 threo-3-hydroxy-L-aspartate ammonia-lyase D 4.3.1.17 L-serine ammonia-lyase D 4.3.1.18 D-serine ammonia-lyase D 4.3.1.19 threonine ammonia-lyase D 4.3.1.20 erythro-3-hydroxy-L-aspartate ammonia-lyase D 4.3.1.22 3,4-dihydroxyphenylalanine reductive deaminase D 4.3.1.23 tyrosine ammonia-lyase D 4.3.1.24 phenylalanine ammonia-lyase D 4.3.1.25 phenylalanine/tyrosine ammonia-lyase D 4.3.1.26 chromopyrrolate synthase D 4.3.1.27 threo-3-hydroxy-D-aspartate ammonia-lyase D 4.3.1.28 L-lysine cyclodeaminase D 4.3.1.- C 4.3.2 Amidine-lyases D 4.3.2.1 argininosuccinate lyase E PRU_2393 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D 4.3.2.2 adenylosuccinate lyase E PRU_0056 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D 4.3.2.3 ureidoglycolate lyase D 4.3.2.4 purine imidazole-ring cyclase D 4.3.2.5 peptidylamidoglycolate lyase D 4.3.2.6 gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase C 4.3.3 Amine-lyases D 4.3.3.1 3-ketovalidoxylamine C-N-lyase D 4.3.3.2 strictosidine synthase D 4.3.3.3 deacetylisoipecoside synthase D 4.3.3.4 deacetylipecoside synthase D 4.3.3.5 4'-demethylrebeccamycin synthase D 4.3.3.6 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) D 4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase E PRU_1224 dapA; dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D 4.3.3.- C 4.3.99 Other carbon-nitrogen lyases D 4.3.99.2 carboxybiotin decarboxylase D 4.3.99.3 7-carboxy-7-deazaguanine synthase D 4.3.99.4 choline trimethylamine-lyase C 4.3.- Carbon-nitrogen lyases D 4.3.-.- B 4.4 Carbon-sulfur lyases C 4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date) D 4.4.1.1 cystathionine gamma-lyase D 4.4.1.2 homocysteine desulfhydrase D 4.4.1.3 dimethylpropiothetin dethiomethylase D 4.4.1.4 alliin lyase D 4.4.1.5 lactoylglutathione lyase D 4.4.1.6 S-alkylcysteine lyase D 4.4.1.8 cystathionine beta-lyase E PRU_2309 class I/II aminotransferase K14155 patB; cystathione beta-lyase [EC:4.4.1.8] D 4.4.1.9 L-3-cyanoalanine synthase D 4.4.1.10 cysteine lyase D 4.4.1.11 methionine gamma-lyase D 4.4.1.13 cysteine-S-conjugate beta-lyase D 4.4.1.14 1-aminocyclopropane-1-carboxylate synthase D 4.4.1.15 D-cysteine desulfhydrase D 4.4.1.16 selenocysteine lyase E PRU_2376 sufS; cysteine desulfurase SufS K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D 4.4.1.17 holocytochrome-c synthase D 4.4.1.19 phosphosulfolactate synthase D 4.4.1.20 leukotriene-C4 synthase D 4.4.1.21 S-ribosylhomocysteine lyase E PRU_0125 luxS; autoinducer-2 production protein LuxS K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D 4.4.1.22 S-(hydroxymethyl)glutathione synthase D 4.4.1.23 2-hydroxypropyl-CoM lyase D 4.4.1.24 (2R)-sulfolactate sulfo-lyase D 4.4.1.25 L-cysteate sulfo-lyase D 4.4.1.26 olivetolic acid cyclase D 4.4.1.- C 4.4.- Carbon-sulfur lyases D 4.4.-.- B 4.5 Carbon-halide lyases C 4.5.1 Carbon-halide lyases (only sub-subclass identified to date) D 4.5.1.1 DDT-dehydrochlorinase D 4.5.1.2 3-chloro-D-alanine dehydrochlorinase D 4.5.1.3 dichloromethane dehalogenase D 4.5.1.4 L-2-amino-4-chloropent-4-enoate dehydrochlorinase D 4.5.1.5 S-carboxymethylcysteine synthase D 4.5.1.- B 4.6 Phosphorus-oxygen lyases C 4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date) D 4.6.1.1 adenylate cyclase D 4.6.1.2 guanylate cyclase D 4.6.1.6 cytidylate cyclase D 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase E PRU_2689 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D 4.6.1.13 phosphatidylinositol diacylglycerol-lyase D 4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase D 4.6.1.15 FAD-AMP lyase (cyclizing) D 4.6.1.- B 4.7 carbon-phosphorus lyases C 4.7.1 carbon-phosphorus lyases (only sub-subclass identified to date) D 4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase B 4.99 Other lyases C 4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses D 4.99.1.1 ferrochelatase D 4.99.1.2 alkylmercury lyase D 4.99.1.3 sirohydrochlorin cobaltochelatase E PRU_1084 cobalt chelatase K02190 cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] D 4.99.1.4 sirohydrochlorin ferrochelatase D 4.99.1.5 aliphatic aldoxime dehydratase D 4.99.1.6 indoleacetaldoxime dehydratase D 4.99.1.7 phenylacetaldoxime dehydratase D 4.99.1.8 heme ligase D 4.99.1.- B 4.- C 4.-.- D 4.-.-.- E PRU_2767 pyridoxine biosynthesis protein K06215 pdxS; pyridoxine biosynthesis protein [EC:4.-.-.-] # A5. Isomerases B 5.1 Racemases and epimerases C 5.1.1 Acting on amino acids and derivatives D 5.1.1.1 alanine racemase E PRU_0131 alanine racemase/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01775 alr; alanine racemase [EC:5.1.1.1] D 5.1.1.2 methionine racemase D 5.1.1.3 glutamate racemase E PRU_2287 murI; glutamate racemase K01776 E5.1.1.3; glutamate racemase [EC:5.1.1.3] D 5.1.1.4 proline racemase D 5.1.1.5 lysine racemase D 5.1.1.6 threonine racemase D 5.1.1.7 diaminopimelate epimerase E PRU_1958 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D 5.1.1.8 4-hydroxyproline epimerase D 5.1.1.9 arginine racemase D 5.1.1.10 amino-acid racemase D 5.1.1.11 phenylalanine racemase (ATP-hydrolysing) D 5.1.1.12 ornithine racemase D 5.1.1.13 aspartate racemase D 5.1.1.14 nocardicin-A epimerase D 5.1.1.15 2-aminohexano-6-lactam racemase D 5.1.1.16 protein-serine epimerase D 5.1.1.17 isopenicillin-N epimerase D 5.1.1.18 serine racemase D 5.1.1.- C 5.1.2 Acting on hydroxy acids and derivatives D 5.1.2.1 lactate racemase D 5.1.2.2 mandelate racemase D 5.1.2.3 3-hydroxybutyryl-CoA epimerase D 5.1.2.4 acetoin racemase D 5.1.2.5 tartrate epimerase D 5.1.2.6 isocitrate epimerase D 5.1.2.- C 5.1.3 Acting on carbohydrates and derivatives D 5.1.3.1 ribulose-phosphate 3-epimerase E PRU_0232 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D 5.1.3.2 UDP-glucose 4-epimerase E PRU_0450 NAD-dependent epimerase/dehydratase family protein K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] E PRU_0847 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D 5.1.3.3 aldose 1-epimerase E PRU_0424 galM_1; aldose 1-epimerase K01785 E5.1.3.3; aldose 1-epimerase [EC:5.1.3.3] E PRU_0427 galM_2; aldose 1-epimerase K01785 E5.1.3.3; aldose 1-epimerase [EC:5.1.3.3] D 5.1.3.4 L-ribulose-5-phosphate 4-epimerase E PRU_0421 L-ribulose-5-phosphate 4-epimerase K01786 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D 5.1.3.5 UDP-arabinose 4-epimerase D 5.1.3.6 UDP-glucuronate 4-epimerase D 5.1.3.7 UDP-N-acetylglucosamine 4-epimerase D 5.1.3.8 N-acylglucosamine 2-epimerase D 5.1.3.9 N-acylglucosamine-6-phosphate 2-epimerase D 5.1.3.10 CDP-paratose 2-epimerase D 5.1.3.11 cellobiose epimerase D 5.1.3.12 UDP-glucuronate 5'-epimerase D 5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase E PRU_0085 rfbC_1; dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13] D 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) E PRU_1368 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase [EC:5.1.3.14] E PRU_0103 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase [EC:5.1.3.14] D 5.1.3.15 glucose-6-phosphate 1-epimerase D 5.1.3.16 UDP-glucosamine 4-epimerase D 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase D 5.1.3.18 GDP-mannose 3,5-epimerase D 5.1.3.19 chondroitin-glucuronate 5-epimerase D 5.1.3.20 ADP-glyceromanno-heptose 6-epimerase D 5.1.3.21 maltose epimerase D 5.1.3.22 L-ribulose-5-phosphate 3-epimerase D 5.1.3.23 UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase D 5.1.3.24 N-acetylneuraminate epimerase D 5.1.3.25 dTDP-L-rhamnose 4-epimerase D 5.1.3.- E PRU_1471 hypothetical protein K03534 rhaM; L-rhamnose mutarotase [EC:5.1.3.-] E PRU_2782 hypothetical protein K03534 rhaM; L-rhamnose mutarotase [EC:5.1.3.-] C 5.1.99 Acting on other compounds D 5.1.99.1 methylmalonyl-CoA epimerase E PRU_1230 glyoxalase family protein K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] D 5.1.99.2 16-hydroxysteroid epimerase D 5.1.99.3 allantoin racemase D 5.1.99.4 alpha-methylacyl-CoA racemase D 5.1.99.5 hydantoin racemase D 5.1.99.6 NAD(P)H-hydrate epimerase D 5.1.99.- C 5.1.- Racemases and epimerases D 5.1.-.- B 5.2 cis-trans-Isomerases C 5.2.1 cis-trans Isomerases (only sub-subclass identified to date) D 5.2.1.1 maleate isomerase D 5.2.1.2 maleylacetoacetate isomerase D 5.2.1.4 maleylpyruvate isomerase D 5.2.1.5 linoleate isomerase D 5.2.1.6 furylfuramide isomerase D 5.2.1.8 peptidylprolyl isomerase E PRU_0493 peptidyl-prolyl cis-trans isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] E PRU_1096 peptidyl-prolyl cis-trans isomerase K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] E PRU_0033 peptidylprolyl isomerase domain-containing protein K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] E PRU_0034 peptidylprolyl isomerase domain-containing protein K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] E PRU_2860 fklB; FKBP family peptidyl-prolyl cis-trans isomerase K03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8] E PRU_0545 peptidyl-prolyl cis-trans isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D 5.2.1.9 farnesol 2-isomerase D 5.2.1.10 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase D 5.2.1.12 zeta-carotene isomerase D 5.2.1.13 prolycopene isomerase D 5.2.1.14 beta-carotene isomerase D 5.2.1.- B 5.3 Intramolecular oxidoreductases C 5.3.1 Interconverting aldoses and ketoses, and related compounds D 5.3.1.1 triose-phosphate isomerase E PRU_1860 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D 5.3.1.3 arabinose isomerase D 5.3.1.4 L-arabinose isomerase E PRU_0420 araA; L-arabinose isomerase K01804 araA; L-arabinose isomerase [EC:5.3.1.4] D 5.3.1.5 xylose isomerase D 5.3.1.6 ribose-5-phosphate isomerase E PRU_0392 rpiB; ribose-5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] D 5.3.1.7 mannose isomerase D 5.3.1.8 mannose-6-phosphate isomerase E PRU_2880 manA; mannose-6-phosphate isomerase, class I K01809 E5.3.1.8; mannose-6-phosphate isomerase [EC:5.3.1.8] D 5.3.1.9 glucose-6-phosphate isomerase E PRU_1785 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D 5.3.1.12 glucuronate isomerase E PRU_1363 uxaC; glucuronate isomerase K01812 uxaC; glucuronate isomerase [EC:5.3.1.12] D 5.3.1.13 arabinose-5-phosphate isomerase E PRU_1627 sugar isomerase K06041 E5.3.1.13; arabinose-5-phosphate isomerase [EC:5.3.1.13] E PRU_0446 sugar isomerase K06041 E5.3.1.13; arabinose-5-phosphate isomerase [EC:5.3.1.13] D 5.3.1.14 L-rhamnose isomerase E PRU_1467 rhaA; L-rhamnose isomerase K01813 rhaA; L-rhamnose isomerase [EC:5.3.1.14] D 5.3.1.15 D-lyxose ketol-isomerase D 5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase E PRU_0484 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814 E5.3.1.16; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D 5.3.1.17 5-dehydro-4-deoxy-D-glucuronate isomerase E PRU_1290 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase K01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] D 5.3.1.20 ribose isomerase D 5.3.1.21 corticosteroid side-chain-isomerase D 5.3.1.22 hydroxypyruvate isomerase D 5.3.1.23 S-methyl-5-thioribose-1-phosphate isomerase D 5.3.1.24 phosphoribosylanthranilate isomerase D 5.3.1.25 L-fucose isomerase E PRU_2781 fucI; arabinose isomerase K01818 fucI; L-fucose isomerase [EC:5.3.1.25] D 5.3.1.26 galactose-6-phosphate isomerase D 5.3.1.27 6-phospho-3-hexuloisomerase D 5.3.1.28 D-sedoheptulose 7-phosphate isomerase D 5.3.1.- C 5.3.2 Interconverting keto- and enol-groups D 5.3.2.1 phenylpyruvate tautomerase D 5.3.2.2 oxaloacetate tautomerase D 5.3.2.3 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming) D 5.3.2.4 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) D 5.3.2.5 2,3-diketo-5-methylthiopentyl-1-phosphate enolase D 5.3.2.6 2-hydroxymuconate tautomerase D 5.3.2.7 ascopyrone tautomerase D 5.3.2.8 4-oxalomesaconate tautomerase D 5.3.2.- C 5.3.3 Transposing C=C bonds D 5.3.3.1 steroid Delta-isomerase D 5.3.3.2 isopentenyl-diphosphate Delta-isomerase D 5.3.3.3 vinylacetyl-CoA Delta-isomerase D 5.3.3.4 muconolactone Delta-isomerase D 5.3.3.5 cholestenol Delta-isomerase D 5.3.3.6 methylitaconate Delta-isomerase D 5.3.3.7 aconitate Delta-isomerase D 5.3.3.8 dodecenoyl-CoA isomerase D 5.3.3.9 prostaglandin-A1 Delta-isomerase D 5.3.3.10 5-carboxymethyl-2-hydroxymuconate Delta-isomerase D 5.3.3.11 isopiperitenone Delta-isomerase D 5.3.3.12 L-dopachrome isomerase D 5.3.3.13 polyenoic fatty acid isomerase D 5.3.3.14 trans-2-decenoyl-[acyl-carrier protein] isomerase D 5.3.3.17 trans-2,3-dihydro-3-hydroxyanthranilate isomerase D 5.3.3.18 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase D 5.3.3.- C 5.3.4 Transposing S-S bonds D 5.3.4.1 protein disulfide-isomerase C 5.3.99 Other intramolecular oxidoreductases D 5.3.99.2 prostaglandin-D synthase D 5.3.99.3 prostaglandin-E synthase D 5.3.99.4 prostaglandin-I synthase D 5.3.99.5 thromboxane-A synthase D 5.3.99.6 allene-oxide cyclase D 5.3.99.7 styrene-oxide isomerase D 5.3.99.8 capsanthin/capsorubin synthase D 5.3.99.9 neoxanthin synthase D 5.3.99.10 thiazole tautomerase D 5.3.99.- B 5.4 Intramolecular transferases C 5.4.1 Transferring acyl groups D 5.4.1.1 lysolecithin acylmutase D 5.4.1.2 precorrin-8X methylmutase C 5.4.2 Phosphotransferases (phosphomutases) D 5.4.2.1 phosphoglycerate mutase E PRU_2355 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.1] E PRU_1341 phosphoglycerate mutase family protein K15634 gpmB; probable phosphoglycerate mutase [EC:5.4.2.1] E PRU_1017 homoserine kinase K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.1] D 5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) D 5.4.2.3 phosphoacetylglucosamine mutase D 5.4.2.4 bisphosphoglycerate mutase D 5.4.2.5 phosphoglucomutase (glucose-cofactor) D 5.4.2.6 beta-phosphoglucomutase D 5.4.2.7 phosphopentomutase D 5.4.2.8 phosphomannomutase E PRU_1071 phosphoglucomutase/phosphomannomutase family protein K01840 E5.4.2.8; phosphomannomutase [EC:5.4.2.8] E PRU_0304 phosphoglucomutase/phosphomannomutase family protein K01840 E5.4.2.8; phosphomannomutase [EC:5.4.2.8] D 5.4.2.9 phosphoenolpyruvate mutase D 5.4.2.10 phosphoglucosamine mutase D 5.4.2.- C 5.4.3 Transferring amino groups D 5.4.3.2 lysine 2,3-aminomutase D 5.4.3.3 beta-lysine 5,6-aminomutase D 5.4.3.4 D-lysine 5,6-aminomutase D 5.4.3.5 D-ornithine 4,5-aminomutase D 5.4.3.6 tyrosine 2,3-aminomutase D 5.4.3.7 leucine 2,3-aminomutase D 5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase D 5.4.3.9 glutamate 2,3-aminomutase D 5.4.3.10 phenylalanine aminomutase (L-beta-phenylalanine forming) D 5.4.3.11 phenylalanine aminomutase (D-beta-phenylalanine forming) C 5.4.4 Transferring hydroxy groups D 5.4.4.1 (hydroxyamino)benzene mutase D 5.4.4.2 isochorismate synthase E PRU_1686 menF; menaquinone-specific isochorismate synthase K02361 entC; isochorismate synthase [EC:5.4.4.2] D 5.4.4.3 3-(hydroxyamino)phenol mutase D 5.4.4.4 geraniol isomerase D 5.4.4.5 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase D 5.4.4.6 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase D 5.4.4.- C 5.4.99 Transferring other groups D 5.4.99.1 methylaspartate mutase D 5.4.99.2 methylmalonyl-CoA mutase E PRU_1639 mutB; methylmalonyl-CoA mutase large subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] E PRU_1640 mutA; methylmalonyl-CoA mutase small subunit K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] D 5.4.99.3 2-acetolactate mutase D 5.4.99.4 2-methyleneglutarate mutase D 5.4.99.5 chorismate mutase E PRU_1172 phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase K04516 AROA1; chorismate mutase [EC:5.4.99.5] D 5.4.99.7 lanosterol synthase D 5.4.99.8 cycloartenol synthase D 5.4.99.9 UDP-galactopyranose mutase E PRU_1527 glf; UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9] D 5.4.99.11 isomaltulose synthase D 5.4.99.12 tRNA pseudouridine38-40 synthase E PRU_1253 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D 5.4.99.13 isobutyryl-CoA mutase D 5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase D 5.4.99.15 (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase D 5.4.99.16 maltose alpha-D-glucosyltransferase D 5.4.99.17 squalene---hopene cyclase D 5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase E PRU_2857 purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D 5.4.99.19 16S rRNA pseudouridine516 synthase D 5.4.99.20 23S rRNA pseudouridine2457 synthase D 5.4.99.21 23S rRNA pseudouridine2604 synthase D 5.4.99.22 23S rRNA pseudouridine2605 synthase E PRU_0055 rluB; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D 5.4.99.23 23S rRNA pseudouridine1911/1915/1917 synthase E PRU_2236 ribosomal large subunit pseudouridine synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] E PRU_1362 RNA pseudouridine synthase family protein K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] E PRU_0298 RNA pseudouridine synthase family protein K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D 5.4.99.24 23S rRNA pseudouridine955/2504/2580 synthase D 5.4.99.25 tRNA pseudouridine55 synthase E PRU_1832 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D 5.4.99.26 tRNA pseudouridine65 synthase D 5.4.99.27 tRNA pseudouridine13 synthase D 5.4.99.28 tRNA pseudouridine32 synthase E PRU_2661 rluA; ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D 5.4.99.29 23S rRNA pseudouridine746 synthase E PRU_2661 rluA; ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D 5.4.99.30 UDP-arabinopyranose mutase D 5.4.99.31 thalianol synthase D 5.4.99.32 protostadienol synthase D 5.4.99.33 cucurbitadienol synthase D 5.4.99.34 germanicol synthase D 5.4.99.35 taraxerol synthase D 5.4.99.36 isomultiflorenol synthase D 5.4.99.37 dammaradiene synthase D 5.4.99.38 camelliol C synthase D 5.4.99.39 beta-amyrin synthase D 5.4.99.40 alpha-amyrin synthase D 5.4.99.41 lupeol synthase D 5.4.99.42 tRNA pseudouridine31 synthase D 5.4.99.43 21S rRNA pseudouridine2819 synthase D 5.4.99.44 mitochondrial tRNA pseudouridine27/28 synthase D 5.4.99.45 tRNA pseudouridine38/39 synthase D 5.4.99.46 shionone synthase D 5.4.99.47 parkeol synthase D 5.4.99.48 achilleol B synthase D 5.4.99.49 glutinol synthase D 5.4.99.50 friedelin synthase D 5.4.99.51 baccharis oxide synthase D 5.4.99.52 alpha-seco-amyrin synthase D 5.4.99.53 marneral synthase D 5.4.99.54 beta-seco-amyrin synthase D 5.4.99.55 delta-amyrin synthase D 5.4.99.56 tirucalladienol synthase D 5.4.99.57 baruol synthase D 5.4.99.58 methylornithine synthase D 5.4.99.- B 5.5 Intramolecular lyases C 5.5.1 Intramolecular lyases (only sub-subclass identified to date) D 5.5.1.1 muconate cycloisomerase D 5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase D 5.5.1.3 tetrahydroxypteridine cycloisomerase D 5.5.1.4 inositol-3-phosphate synthase E PRU_1281 inositol-3-phosphate synthase K01858 E5.5.1.4; myo-inositol-1-phosphate synthase [EC:5.5.1.4] D 5.5.1.5 carboxy-cis,cis-muconate cyclase D 5.5.1.6 chalcone isomerase D 5.5.1.7 chloromuconate cycloisomerase D 5.5.1.8 (+)-bornyl diphosphate synthase D 5.5.1.9 cycloeucalenol cycloisomerase D 5.5.1.10 alpha-pinene-oxide decyclase D 5.5.1.11 dichloromuconate cycloisomerase D 5.5.1.12 copalyl diphosphate synthase D 5.5.1.13 ent-copalyl diphosphate synthase D 5.5.1.14 syn-copalyl-diphosphate synthase D 5.5.1.15 terpentedienyl-diphosphate synthase D 5.5.1.16 halimadienyl-diphosphate synthase D 5.5.1.17 (S)-beta-macrocarpene synthase D 5.5.1.18 lycopene epsilon-cyclase D 5.5.1.19 lycopene beta-cyclase D 5.5.1.20 prosolanapyrone-III cycloisomerase D 5.5.1.- B 5.99 Other isomerases C 5.99.1 Sole sub-subclass for isomerases that do not belong in the other subclasses D 5.99.1.1 thiocyanate isomerase D 5.99.1.2 DNA topoisomerase E PRU_2627 topA; DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.99.1.2] E PRU_1269 topB; DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.99.1.2] D 5.99.1.3 DNA topoisomerase (ATP-hydrolysing) E PRU_0813 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.99.1.3] E PRU_2340 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.99.1.3] D 5.99.1.4 2-hydroxychromene-2-carboxylate isomerase D 5.99.1.- E PRU_0008 topoisomerase gyrA/parC subunit family protein K02621 parC; topoisomerase IV subunit A [EC:5.99.1.-] E PRU_2475 type II topoisomerase family protein K02622 parE; topoisomerase IV subunit B [EC:5.99.1.-] B 5.- C 5.-.- D 5.-.-.- # A6. Ligases B 6.1 Forming carbon-oxygen bonds C 6.1.1 Ligases forming aminoacyl-tRNA and related compounds D 6.1.1.1 tyrosine---tRNA ligase E PRU_2299 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D 6.1.1.2 tryptophan---tRNA ligase E PRU_0558 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D 6.1.1.3 threonine---tRNA ligase E PRU_0593 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D 6.1.1.4 leucine---tRNA ligase E PRU_2527 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D 6.1.1.5 isoleucine---tRNA ligase E PRU_1069 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D 6.1.1.6 lysine---tRNA ligase E PRU_1691 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D 6.1.1.7 alanine---tRNA ligase E PRU_0009 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D 6.1.1.9 valine---tRNA ligase E PRU_1414 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D 6.1.1.10 methionine---tRNA ligase E PRU_2535 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D 6.1.1.11 serine---tRNA ligase E PRU_0700 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D 6.1.1.12 aspartate---tRNA ligase E PRU_1439 aspS; aspartate--tRNA ligase K01876 DARS; aspartyl-tRNA synthetase [EC:6.1.1.12] D 6.1.1.13 D-alanine---poly(phosphoribitol) ligase D 6.1.1.14 glycine---tRNA ligase E PRU_2876 glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14] D 6.1.1.15 proline---tRNA ligase E PRU_1061 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D 6.1.1.16 cysteine---tRNA ligase E PRU_2836 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D 6.1.1.17 glutamate---tRNA ligase E PRU_2167 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D 6.1.1.18 glutamine---tRNA ligase E PRU_1373 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D 6.1.1.19 arginine---tRNA ligase E PRU_2401 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D 6.1.1.20 phenylalanine---tRNA ligase E PRU_0582 pheS; phenylalanyl-tRNA synthetase subunit alpha K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] E PRU_0820 pheT; phenylalanyl-tRNA synthetase subunit beta K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D 6.1.1.21 histidine---tRNA ligase E PRU_0984 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D 6.1.1.22 asparagine---tRNA ligase E PRU_0054 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D 6.1.1.23 aspartate---tRNAAsn ligase D 6.1.1.24 glutamate---tRNAGln ligase D 6.1.1.26 pyrrolysine---tRNAPyl ligase D 6.1.1.27 O-phospho-L-serine---tRNA ligase D 6.1.1.- C 6.1.2 acid-alcohol ligases (ester synthases) D 6.1.2.1 D-alanine---(R)-lactate ligase B 6.2 Forming carbon-sulfur bonds C 6.2.1 Acid-thiol ligases D 6.2.1.1 acetate---CoA ligase E PRU_2205 AMP-binding enzyme K01895 ACSS; acetyl-CoA synthetase [EC:6.2.1.1] D 6.2.1.2 butyrate---CoA ligase D 6.2.1.3 long-chain-fatty-acid---CoA ligase E PRU_1303 AMP-binding enzyme K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] E PRU_2490 AMP-binding enzyme K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D 6.2.1.4 succinate---CoA ligase (GDP-forming) D 6.2.1.5 succinate---CoA ligase (ADP-forming) D 6.2.1.6 glutarate---CoA ligase D 6.2.1.7 cholate---CoA ligase D 6.2.1.8 oxalate---CoA ligase D 6.2.1.9 malate---CoA ligase D 6.2.1.10 carboxylic acid---CoA ligase (GDP-forming) D 6.2.1.11 biotin---CoA ligase D 6.2.1.12 4-coumarate---CoA ligase D 6.2.1.13 acetate---CoA ligase (ADP-forming) D 6.2.1.14 6-carboxyhexanoate---CoA ligase D 6.2.1.15 arachidonate---CoA ligase D 6.2.1.16 acetoacetate---CoA ligase D 6.2.1.17 propionate---CoA ligase D 6.2.1.18 citrate---CoA ligase D 6.2.1.19 long-chain-fatty-acid---luciferin-component ligase D 6.2.1.20 long-chain-fatty-acid---[acyl-carrier-protein] ligase D 6.2.1.22 [citrate (pro-3S)-lyase] ligase D 6.2.1.23 dicarboxylate---CoA ligase D 6.2.1.24 phytanate---CoA ligase D 6.2.1.25 benzoate---CoA ligase D 6.2.1.26 o-succinylbenzoate---CoA ligase E PRU_1682 O-succinylbenzoic acid--CoA ligase-like protein K01911 menE; O-succinylbenzoic acid--CoA ligase [EC:6.2.1.26] D 6.2.1.27 4-hydroxybenzoate---CoA ligase D 6.2.1.28 3alpha,7alpha-dihydroxy-5beta-cholestanate---CoA ligase D 6.2.1.30 phenylacetate---CoA ligase E PRU_1063 phenylacetate--CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] E PRU_0059 phenylacetate-CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30] D 6.2.1.31 2-furoate---CoA ligase D 6.2.1.32 anthranilate---CoA ligase D 6.2.1.33 4-chlorobenzoate---CoA ligase D 6.2.1.34 trans-feruloyl-CoA synthase D 6.2.1.35 ACP-SH:acetate ligase D 6.2.1.36 3-hydroxypropionyl-CoA synthase D 6.2.1.37 3-hydroxybenzoate---CoA ligase D 6.2.1.38 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase D 6.2.1.39 [butirosin acyl-carrier protein]---L-glutamate ligase D 6.2.1.- E PRU_0473 AMP-binding enzyme K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] B 6.3 Forming carbon-nitrogen bonds C 6.3.1 Acid-D-ammonia (or amine) ligases (amide synthases) D 6.3.1.1 aspartate---ammonia ligase E PRU_1711 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D 6.3.1.2 glutamate---ammonia ligase E PRU_2071 glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] E PRU_1957 glnA_2; type III glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] E PRU_1416 glnA_1; type III glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2] D 6.3.1.4 aspartate---ammonia ligase (ADP-forming) D 6.3.1.5 NAD+ synthase D 6.3.1.6 glutamate---ethylamine ligase D 6.3.1.7 4-methyleneglutamate---ammonia ligase D 6.3.1.8 glutathionylspermidine synthase D 6.3.1.9 trypanothione synthase D 6.3.1.10 adenosylcobinamide-phosphate synthase E PRU_1080 cobD; cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D 6.3.1.11 glutamate---putrescine ligase D 6.3.1.12 D-aspartate ligase D 6.3.1.13 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase D 6.3.1.14 diphthine---ammonia ligase C 6.3.2 Acid-D-amino-acid ligases (peptide synthases) D 6.3.2.1 pantoate---beta-alanine ligase E PRU_2451 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D 6.3.2.2 glutamate---cysteine ligase D 6.3.2.3 glutathione synthase D 6.3.2.4 D-alanine---D-alanine ligase E PRU_2235 D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D 6.3.2.5 phosphopantothenate---cysteine ligase E PRU_2453 coaBC; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase [EC:4.1.1.36 6.3.2.5] D 6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase E PRU_0723 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D 6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase D 6.3.2.8 UDP-N-acetylmuramate---L-alanine ligase E PRU_2333 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D 6.3.2.9 UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase E PRU_2330 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D 6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase E PRU_2263 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D 6.3.2.11 carnosine synthase D 6.3.2.12 dihydrofolate synthase E PRU_0428 folC; tetrahydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D 6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase E PRU_2328 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 E6.3.2.13; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D 6.3.2.14 enterobactin synthase D 6.3.2.16 D-alanine---alanyl-poly(glycerolphosphate) ligase D 6.3.2.17 tetrahydrofolate synthase E PRU_0428 folC; tetrahydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D 6.3.2.18 gamma-glutamylhistamine synthase D 6.3.2.19 ubiquitin---protein ligase D 6.3.2.20 indoleacetate---lysine synthetase D 6.3.2.21 ubiquitin---calmodulin ligase D 6.3.2.23 homoglutathione synthase D 6.3.2.24 tyrosine---arginine ligase D 6.3.2.25 tubulin---tyrosine ligase D 6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase D 6.3.2.28 L-amino-acid alpha-ligase D 6.3.2.29 cyanophycin synthase (L-aspartate-adding) D 6.3.2.30 cyanophycin synthase (L-arginine-adding) D 6.3.2.31 coenzyme F420-0:L-glutamate ligase D 6.3.2.32 coenzyme gamma-F420-2:alpha-L-glutamate ligase D 6.3.2.33 tetrahydrosarcinapterin synthase D 6.3.2.34 coenzyme F420-1:gamma-L-glutamate ligase D 6.3.2.35 D-alanine---D-serine ligase D 6.3.2.36 4-phosphopantoate---beta-alanine ligase D 6.3.2.37 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---D-lysine ligase D 6.3.2.38 N2-citryl-N6-acetyl-N6-hydroxylysine synthase D 6.3.2.39 aerobactin synthase D 6.3.2.- C 6.3.3 Cyclo-ligases D 6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase E PRU_0720 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D 6.3.3.2 5-formyltetrahydrofolate cyclo-ligase E PRU_0199 5-formyltetrahydrofolate cyclo-ligase family protein K01934 E6.3.3.2; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] D 6.3.3.3 dethiobiotin synthase D 6.3.3.4 (carboxyethyl)arginine beta-lactam-synthase C 6.3.4 Other carbon-nitrogen ligases D 6.3.4.1 GMP synthase D 6.3.4.2 CTP synthase E PRU_1972 pyrG; CTP synthase K01937 E6.3.4.2; CTP synthase [EC:6.3.4.2] D 6.3.4.3 formate---tetrahydrofolate ligase D 6.3.4.4 adenylosuccinate synthase E PRU_0986 purA; adenylosuccinate synthase K01939 E6.3.4.4; adenylosuccinate synthase [EC:6.3.4.4] D 6.3.4.5 argininosuccinate synthase E PRU_2199 argG; argininosuccinate synthase K01940 E6.3.4.5; argininosuccinate synthase [EC:6.3.4.5] D 6.3.4.6 urea carboxylase D 6.3.4.7 ribose-5-phosphate---ammonia ligase D 6.3.4.8 imidazoleacetate---phosphoribosyldiphosphate ligase D 6.3.4.9 biotin---[methylmalonyl-CoA-carboxytransferase] ligase D 6.3.4.10 biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase D 6.3.4.11 biotin---[methylcrotonoyl-CoA-carboxylase] ligase D 6.3.4.12 glutamate---methylamine ligase D 6.3.4.13 phosphoribosylamine---glycine ligase E PRU_1807 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine--glycine ligase [EC:6.3.4.13] D 6.3.4.14 biotin carboxylase D 6.3.4.15 biotin---[acetyl-CoA-carboxylase] ligase E PRU_1891 biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D 6.3.4.16 carbamoyl-phosphate synthase (ammonia) D 6.3.4.17 formate---dihydrofolate ligase D 6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase D 6.3.4.19 tRNAIle-lysidine synthase E PRU_0903 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D 6.3.4.20 7-cyano-7-deazaguanine synthase E PRU_2594 protein ExsB K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D 6.3.4.- C 6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor D 6.3.5.1 NAD+ synthase (glutamine-hydrolysing) E PRU_0811 nadE; glutamine-dependent NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D 6.3.5.2 GMP synthase (glutamine-hydrolysing) E PRU_1678 guaA; GMP synthase (glutamine-hydrolyzing) K01951 E6.3.5.2; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D 6.3.5.3 phosphoribosylformylglycinamidine synthase E PRU_2663 purL; phosphoribosylformylglycinamidine synthase K01952 purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D 6.3.5.4 asparagine synthase (glutamine-hydrolysing) E PRU_1978 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D 6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing) E PRU_0889 carB; carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] E PRU_1030 carbamoyl-phosphate synthase large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] D 6.3.5.6 asparaginyl-tRNA synthase (glutamine-hydrolysing) D 6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing) D 6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) E PRU_1086 cobB; cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D 6.3.5.10 adenosylcobyric acid synthase (glutamine-hydrolysing) E PRU_1081 cobQ; cobyric acid synthase CobQ K02232 E6.3.5.10; adenosylcobyric acid synthase [EC:6.3.5.10] D 6.3.5.11 cobyrinate a,c-diamide synthase E PRU_1086 cobB; cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D 6.3.5.- C 6.3.- Forming carbon-nitrogen bonds D 6.3.-.- B 6.4 Forming carbon-carbon bonds C 6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date) D 6.4.1.1 pyruvate carboxylase E PRU_0254 pyruvate carboxylase K01960 E6.4.1.1B; pyruvate carboxylase subunit B [EC:6.4.1.1] D 6.4.1.2 acetyl-CoA carboxylase D 6.4.1.3 propionyl-CoA carboxylase E PRU_1231 carboxyl transferase domain-containing protein K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3] D 6.4.1.4 methylcrotonoyl-CoA carboxylase D 6.4.1.5 geranoyl-CoA carboxylase D 6.4.1.6 acetone carboxylase D 6.4.1.7 2-oxoglutarate carboxylase D 6.4.1.8 acetophenone carboxylase D 6.4.1.- C 6.4.- Forming carbon-carbon bonds D 6.4.-.- B 6.5 Forming phosphoric-ester bonds C 6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date) D 6.5.1.1 DNA ligase (ATP) D 6.5.1.2 DNA ligase (NAD+) E PRU_0567 ligA; DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D 6.5.1.3 RNA ligase (ATP) D 6.5.1.4 RNA-3'-phosphate cyclase D 6.5.1.- B 6.6 Forming nitrogen-D-metal bonds C 6.6.1 Forming coordination complexes D 6.6.1.1 magnesium chelatase D 6.6.1.2 cobaltochelatase B 6.- C 6.-.- D 6.-.-.- ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 22, 2013 #
EC numbers assigned by the Nomenclature Committee of IUBMB and IUPAC