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KO |
09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09151 Immune system
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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04970 Salivary secretion [PATH:aml04970]
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04971 Gastric acid secretion [PATH:aml04971]
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04972 Pancreatic secretion [PATH:aml04972]
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04976 Bile secretion [PATH:aml04976]
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04973 Carbohydrate digestion and absorption [PATH:aml04973]
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04974 Protein digestion and absorption [PATH:aml04974]
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04975 Fat digestion and absorption [PATH:aml04975]
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100469736 gastric triacylglycerol lipase isoform X1
100471594 PNLIP; pancreatic triacylglycerol lipase
100470933 PNLIPRP1; inactive pancreatic lipase-related protein 1
100471180 pancreatic lipase-related protein 2 isoform X2
100472032 CEL; LOW QUALITY PROTEIN: bile salt-activated lipase
100484745 PLA2G5; calcium-dependent phospholipase A2
100478212 PLA2G2E; group IIE secretory phospholipase A2
100463545 group IID secretory phospholipase A2
100463798 PLA2G2F; group IIF secretory phospholipase A2
100464051 PLA2G2C; putative inactive group IIC secretory phospholipase A2 isoform X1
100471349 PLA2G10; group 10 secretory phospholipase A2
100479059 PLA2G3; group 3 secretory phospholipase A2 isoform X1
100475358 PLA2G12A; group XIIA secretory phospholipase A2
100480927 PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1
100473488 PLA2G1B; phospholipase A2
117796269 PLA2G2D; group IID secretory phospholipase A2
100481063 CLPS; colipase
100463982 CD36; platelet glycoprotein 4
100474677 GOT2; aspartate aminotransferase, mitochondrial
100483039 FABP2; fatty acid-binding protein, intestinal
100484021 FABP1; fatty acid-binding protein, liver
100475614 SLC27A1; long-chain fatty acid transport protein 1
100482159 SLC27A4; long-chain fatty acid transport protein 4
100476518 AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
100469184 AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta
100475075 PLPP2; phospholipid phosphatase 2 isoform X2
100479871 PLPP1; phospholipid phosphatase 1 isoform X2
100481127 PLPP3; phospholipid phosphatase 3
100469063 MOGAT2; 2-acylglycerol O-acyltransferase 2
100484228 MOGAT3; 2-acylglycerol O-acyltransferase 3
100479095 DGAT1; LOW QUALITY PROTEIN: diacylglycerol O-acyltransferase 1
100468811 DGAT2; diacylglycerol O-acyltransferase 2 isoform X1
100484067 SCARB1; scavenger receptor class B member 1 isoform X5
100478497 NPC1L1; LOW QUALITY PROTEIN: NPC1-like intracellular cholesterol transporter 1
100477493 ACAT2; acetyl-CoA acetyltransferase, cytosolic
100480384 ACAT1; acetyl-CoA acetyltransferase, mitochondrial
100475530 ABCG5; ATP-binding cassette sub-family G member 5
100466630 ABCG8; ATP-binding cassette sub-family G member 8
100480084 APOA4; apolipoprotein A-IV
100473745 APOB; apolipoprotein B-100
100479021 MTTP; microsomal triglyceride transfer protein large subunit
100477643 APOA1; apolipoprotein A-I isoform X1
100483394 ABCA1; phospholipid-transporting ATPase ABCA1
|
K14452 LIPF; gastric triacylglycerol lipase [EC:3.1.1.3]
K14073 PNLIP; pancreatic triacylglycerol lipase [EC:3.1.1.3]
K14074 PNLIPRP1; pancreatic lipase-related protein 1 [EC:3.1.1.3]
K14075 PNLIPRP2; pancreatic lipase-related protein 2 [EC:3.1.1.3]
K12298 CEL; bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K14460 CLPS; colipase
K06259 CD36; CD36 antigen
K14455 GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K08751 FABP2; fatty acid-binding protein 2, intestinal
K08750 FABP1; fatty acid-binding protein 1, liver
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K14457 MOGAT2; 2-acylglycerol O-acyltransferase 2 [EC:2.3.1.22]
K14456 MOGAT3; 2-acylglycerol O-acyltransferase 3 [EC:2.3.1.20 2.3.1.22]
K11155 DGAT1; diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76]
K11160 DGAT2; diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75]
K13885 SCARB1; scavenger receptor class B, member 1
K14461 NPC1L1; Niemann-Pick C1-like protein 1
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K05683 ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)
K05684 ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
K08760 APOA4; apolipoprotein A-IV
K14462 APOB; apolipoprotein B
K14463 MTTP; microsomal triglyceride transfer protein large subunit
K08757 APOA1; apolipoprotein A-I
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
|
04979 Cholesterol metabolism [PATH:aml04979]
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100483394 ABCA1; phospholipid-transporting ATPase ABCA1
100477643 APOA1; apolipoprotein A-I isoform X1
100482804 LPL; lipoprotein lipase
100469078 LCAT; phosphatidylcholine-sterol acyltransferase isoform X2
100476847 LIPG; endothelial lipase isoform X1
100477355 PLTP; phospholipid transfer protein isoform X2
100475921 LIPC; hepatic triacylglycerol lipase
100463982 CD36; platelet glycoprotein 4
100473450 LDLR; low-density lipoprotein receptor isoform X2
100465000 NCEH1; neutral cholesterol ester hydrolase 1 isoform X2
100464310 SOAT1; sterol O-acyltransferase 1
100466845 SOAT2; sterol O-acyltransferase 2 isoform X1
105239773 APOC1; apolipoprotein C-I
100472882 APOC2; apolipoprotein C-II
100476567 APOH; beta-2-glycoprotein 1
100473620 ANGPTL3; angiopoietin-related protein 3
100475013 ANGPTL4; angiopoietin-related protein 4
105238559 ANGPTL8; angiopoietin-like protein 8
100484067 SCARB1; scavenger receptor class B member 1 isoform X5
100465908 SORT1; sortilin isoform X3
100473745 APOB; apolipoprotein B-100
100475196 LDLRAP1; low density lipoprotein receptor adapter protein 1 isoform X1
100467676 MYLIP; E3 ubiquitin-protein ligase MYLIP
100477661 APOE; apolipoprotein E
100476452 LRP1; prolow-density lipoprotein receptor-related protein 1 isoform X1
100475386 LRP2; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 2
100484749 LRPAP1; alpha-2-macroglobulin receptor-associated protein isoform X1
100474016 LIPA; lysosomal acid lipase/cholesteryl ester hydrolase isoform X1
100481038 STARD3; stAR-related lipid transfer protein 3 isoform X1
100463625 VDAC1; voltage-dependent anion-selective channel protein 1
100465507 VDAC2; voltage-dependent anion-selective channel protein 2
100470763 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1
100474562 TSPO; translocator protein
100467882 TSPO2; translocator protein 2
100480153 sterol 26-hydroxylase, mitochondrial isoform X1
100477574 VAPA; vesicle-associated membrane protein-associated protein A isoform X1
100474439 VAPB; vesicle-associated membrane protein-associated protein B/C
100479962 NPC1; NPC intracellular cholesterol transporter 1
100466215 OSBPL5; oxysterol-binding protein-related protein 5 isoform X1
100472330 NPC2; NPC intracellular cholesterol transporter 2
100470257 STAR; steroidogenic acute regulatory protein, mitochondrial
100472361 CIDEB; cell death activator CIDE-B
100463816 cytochrome P450 7A1
100473353 ABCB11; bile salt export pump
100475530 ABCG5; ATP-binding cassette sub-family G member 5
100466630 ABCG8; ATP-binding cassette sub-family G member 8
100482212 APOA2; apolipoprotein A-II
100477899 APOC3; apolipoprotein C-III
100480084 APOA4; apolipoprotein A-IV
|
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
K08757 APOA1; apolipoprotein A-I
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K00650 LCAT; lecithin-cholesterol acyltransferase [EC:2.3.1.43]
K22284 LIPG; endothelial lipase [EC:3.1.1.3]
K08761 PLTP; phospholipid transfer protein
K22283 LIPC; hepatic triacylglycerol lipase [EC:3.1.1.3]
K06259 CD36; CD36 antigen
K12473 LDLR; low-density lipoprotein receptor
K14349 NCEH1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K00637 SOAT; sterol O-acyltransferase [EC:2.3.1.26]
K00637 SOAT; sterol O-acyltransferase [EC:2.3.1.26]
K22286 APOC1; apolipoprotein C-I
K22287 APOC2; apolipoprotein C-II
K17305 APOH; beta-2-glycoprotein 1
K22288 ANGPTL3; angiopoietin-like 3
K08767 ANGPTL4; angiopoietin-like 4
K22289 ANGPTL8; angiopoietin-like 8
K13885 SCARB1; scavenger receptor class B, member 1
K12388 SORT1; sortilin
K14462 APOB; apolipoprotein B
K12474 LDLRAP1; low density lipoprotein receptor adapter protein 1
K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
K04524 APOE; apolipoprotein E
K04550 LRP1; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K06233 LRP2; low density lipoprotein-related protein 2
K22290 LRPAP1; alpha-2-macroglobulin receptor-associated protein
K01052 LIPA; lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
K22291 STARD3; StAR-related lipid transfer protein 3
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO; translocator protein
K05770 TSPO; translocator protein
K00488 CYP27A1; cholestanetriol 26-monooxygenase [EC:1.14.15.15]
K06096 VAPA; vesicle-associated membrane protein-associated protein A
K10707 VAPB; vesicle-associated membrane protein-associated protein B
K12385 NPC1; Niemann-Pick C1 protein
K20464 OSBPL5; oxysterol-binding protein-related protein 5
K13443 NPC2; Niemann-Pick C2 protein
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K25914 CIDEB; cell death activator CIDE-B
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
K05683 ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)
K05684 ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
K08758 APOA2; apolipoprotein A-II
K08759 APOC3; apolipoprotein C-III
K08760 APOA4; apolipoprotein A-IV
|
04977 Vitamin digestion and absorption [PATH:aml04977]
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100482297 CBLIF; cobalamin binding intrinsic factor
100463652 CUBN; cubilin
100483674 AMN; protein amnionless
100483102 LMBRD1; probable lysosomal cobalamin transporter
100479969 ABCD4; ATP-binding cassette sub-family D member 4 isoform X1
100466484 MMACHC; methylmalonic aciduria and homocystinuria type C protein isoform X1
100464941 ABCC1; multidrug resistance-associated protein 1
100480568 TCN2; transcobalamin-2
100477901 SLC19A3; LOW QUALITY PROTEIN: thiamine transporter 2
100468075 SLC19A2; thiamine transporter 1 isoform X1
100478156 LOW QUALITY PROTEIN: thiamine transporter 2-like
100472037 SLC52A3; solute carrier family 52, riboflavin transporter, member 3
100483327 BTD; biotinidase isoform X1
100466386 SLC5A6; sodium-dependent multivitamin transporter
100474859 SLC23A1; solute carrier family 23 member 1 isoform X1
100474749 solute carrier family 23 member 1 isoform X1
100472805 glutamate carboxypeptidase 2 isoform X2
100468045 SLC46A1; proton-coupled folate transporter isoform X1
100464327 SLC19A1; reduced folate transporter isoform X1
100484067 SCARB1; scavenger receptor class B member 1 isoform X5
100471594 PNLIP; pancreatic triacylglycerol lipase
100471208 PLB1; phospholipase B1, membrane-associated
100463706 RBP2; retinol-binding protein 2
100475313 AWAT2; acyl-CoA wax alcohol acyltransferase 2
100482038 LRAT; lecithin retinol acyltransferase
100473745 APOB; apolipoprotein B-100
100480084 APOA4; apolipoprotein A-IV
100477643 APOA1; apolipoprotein A-I isoform X1
|
K14615 CBLIF; gastric intrinsic factor
K14616 CUBN; cubilin
K18259 AMN; protein amnionless
K14617 LMBRD1; LMBR1 domain-containing protein 1
K05678 ABCD4; ATP-binding cassette, subfamily D (ALD), member 4 [EC:7.6.2.8]
K14618 MMACHC; cyanocobalamin reductase (cyanide-eliminating) / alkylcobalamin dealkylase [EC:1.16.1.6 2.5.1.151]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K14619 TCN2; transcobalamin-2
K14610 SLC19A2_3; solute carrier family 19 (thiamine transporter), member 2/3
K14610 SLC19A2_3; solute carrier family 19 (thiamine transporter), member 2/3
K14610 SLC19A2_3; solute carrier family 19 (thiamine transporter), member 2/3
K14620 SLC52A3; riboflavin transporter 2
K01435 BTD; biotinidase [EC:3.5.1.12]
K14386 SLC5A6; solute carrier family 5 (sodium-dependent multivitamin transporter), member 6
K14611 SLC23A1; solute carrier family 23 (nucleobase transporter), member 1
K14611 SLC23A1; solute carrier family 23 (nucleobase transporter), member 1
K14592 FOLH1; glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
K14613 SLC46A1; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
K14609 SLC19A1; solute carrier family 19 (folate transporter), member 1
K13885 SCARB1; scavenger receptor class B, member 1
K14073 PNLIP; pancreatic triacylglycerol lipase [EC:3.1.1.3]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K14622 RBP2; retinol binding protein 2
K11156 DGAT2L4; diacylglycerol O-acyltransferase 2-like protein 4 [EC:2.3.1.75 2.3.1.76]
K00678 LRAT; phosphatidylcholine-retinol O-acyltransferase [EC:2.3.1.135]
K14462 APOB; apolipoprotein B
K08760 APOA4; apolipoprotein A-IV
K08757 APOA1; apolipoprotein A-I
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04980 Cobalamin transport and metabolism [PATH:aml04980]
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04978 Mineral absorption [PATH:aml04978]
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
|
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09161 Cancer: overview
|
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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05417 Lipid and atherosclerosis [PATH:aml05417]
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100473745 APOB; apolipoprotein B-100
100480084 APOA4; apolipoprotein A-IV
100477643 APOA1; apolipoprotein A-I isoform X1
100473450 LDLR; low-density lipoprotein receptor isoform X2
100471706 OLR1; oxidized low-density lipoprotein receptor 1 isoform X3
100477081 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1
100478167 MMP1; LOW QUALITY PROTEIN: interstitial collagenase
100481181 LOW QUALITY PROTEIN: interstitial collagenase
100476723 RHOA; transforming protein RhoA
100466003 ROCK2; rho-associated protein kinase 2 isoform X1
100483990 NOS3; nitric oxide synthase, endothelial isoform X2
100463775 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100479294 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
100479580 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
100475291 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100483828 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
100467916 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
100468763 AKT2; RAC-beta serine/threonine-protein kinase
100480414 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100465793 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100471095 BAX; apoptosis regulator BAX isoform X1
100473937 BAD; bcl2-associated agonist of cell death
100469922 BCL2L1; bcl-2-like protein 1 isoform X1
100484344 BCL2; LOW QUALITY PROTEIN: apoptosis regulator Bcl-2
100477951 MAPK10; mitogen-activated protein kinase 10 isoform X1
100482196 MAPK8; mitogen-activated protein kinase 8 isoform X1
100477600 MAPK9; mitogen-activated protein kinase 9 isoform X2
100479008 SOD2; superoxide dismutase [Mn], mitochondrial
100477326 PRKCA; protein kinase C alpha type
100466388 POU2F3; POU domain, class 2, transcription factor 3 isoform X1
100483288 POU2F1; POU domain, class 2, transcription factor 1 isoform X5
100472278 POU2F2; POU domain, class 2, transcription factor 2 isoform X14
100476345 CD40; tumor necrosis factor receptor superfamily member 5 isoform X2
100467917 CD40LG; CD40 ligand
100473028 LOW QUALITY PROTEIN: cytochrome P450 1A1-like
100482335 cytochrome P450 2J2
100477105 AGER; advanced glycosylation end product-specific receptor isoform X1
100470141 NOX1; NADPH oxidase 1 isoform X1
100468223 cytochrome b-245 heavy chain
109490984 LOW QUALITY PROTEIN: dual oxidase 1
100472606 NCF1; neutrophil cytosol factor 1
100482979 cytochrome b-245 light chain isoform X3
100476832 NCF2; neutrophil cytosol factor 2
100468228 NCF4; neutrophil cytosol factor 4
100465648 RAC1; ras-related C3 botulinum toxin substrate 1
100474271 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
100481360 JAK2; tyrosine-protein kinase JAK2 isoform X1
100469938 STAT3; signal transducer and activator of transcription 3 isoform X1
100465076 CDC42; cell division control protein 42 homolog isoform X1
100475919 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4
100475975 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1
100474867 FOS; proto-oncogene c-Fos
100483834 JUN; transcription factor AP-1
100474348 C-C motif chemokine 2
100476475 ICAM1; intercellular adhesion molecule 1
100472054 CXCL8; interleukin-8
100476678 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3
100469111 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1
100465223 MAPK13; mitogen-activated protein kinase 13
100465476 MAPK14; mitogen-activated protein kinase 14 isoform X3
100480235 MAPK12; mitogen-activated protein kinase 12
100480483 MAPK11; mitogen-activated protein kinase 11
100473836 HRAS; GTPase HRas isoform X1
100483919 KRAS; GTPase KRas isoform X1
100464196 NRAS; GTPase NRas
100470035 MAPK1; mitogen-activated protein kinase 1
100472388 MAPK3; mitogen-activated protein kinase 3
100480158 RELA; transcription factor p65 isoform X1
100467906 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100470595 SELE; E-selectin
100467827 SELP; P-selectin isoform X3
100480380 VCAM1; vascular cell adhesion protein 1 isoform X1
100478420 LOW QUALITY PROTEIN: stromelysin-1
100477912 stromelysin-1
100475429 MMP9; matrix metalloproteinase-9
100473767 FAS; tumor necrosis factor receptor superfamily member 6
100480874 IL1B; interleukin-1 beta
100477151 IL6; interleukin-6 precursor
117803984 interleukin-6-like
100471563 TNF; tumor necrosis factor
100477321 HSPD1; 60 kDa heat shock protein, mitochondrial
100468647 HSPA8; heat shock cognate 71 kDa protein
100483310 heat shock 70 kDa protein 1-like
100483558 heat shock 70 kDa protein 1
100469467 HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6
117800506 heat shock cognate 71 kDa protein-like isoform X1
100470494 HSPA2; heat shock-related 70 kDa protein 2
100484576 HSPA4; heat shock 70 kDa protein 4
100471414 HSP90AB1; LOW QUALITY PROTEIN: heat shock protein HSP 90-beta
100467363 HSP90AA1; LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha
117803466 LOW QUALITY PROTEIN: heat shock protein HSP 90-beta-like
100474020 HSP90B1; endoplasmin
100465129 TLR2; toll-like receptor 2
100472839 lipopolysaccharide-binding protein
100476795 lipopolysaccharide-binding protein isoform X1
100467208 CD14; monocyte differentiation antigen CD14
100468714 LY96; lymphocyte antigen 96 isoform X1
100472815 TLR4; toll-like receptor 4 isoform X1
100470794 TIRAP; toll/interleukin-1 receptor domain-containing adapter protein isoform X2
100479307 MYD88; myeloid differentiation primary response protein MyD88
100469127 IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1
100484977 IRAK1; interleukin-1 receptor-associated kinase 1
100483216 TRAF6; TNF receptor-associated factor 6
100484077 TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X3
100468085 TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1
100466506 MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1
100464675 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100471679 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
100470223 IKBKG; NF-kappa-B essential modulator isoform X1
100466997 NFKBIA; NF-kappa-B inhibitor alpha
100463778 TICAM1; TIR domain-containing adapter molecule 1
100466406 TRAF3; TNF receptor-associated factor 3 isoform X1
100482907 MIB1; E3 ubiquitin-protein ligase MIB1
100472529 MIB2; E3 ubiquitin-protein ligase MIB2
100484543 TANK; TRAF family member-associated NF-kappa-B activator isoform X2
100465112 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
100484104 TBK1; serine/threonine-protein kinase TBK1 isoform X1
100474086 IRF7; LOW QUALITY PROTEIN: interferon regulatory factor 7
100471184 IRF3; interferon regulatory factor 3 isoform X2
100476812 interferon alpha-2
100477312 interferon alpha-1/2
100477562 LOW QUALITY PROTEIN: interferon alpha-1/2
100478321 interferon alpha-1/2
100478068 interferon alpha-like
100476556 IFNB1; interferon beta
100463982 CD36; platelet glycoprotein 4
100482938 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
100479839 RXRA; retinoic acid receptor RXR-alpha
100475696 RXRB; retinoic acid receptor RXR-beta isoform X2
100475450 RXRG; retinoic acid receptor RXR-gamma isoform X1
100479606 LYN; tyrosine-protein kinase Lyn isoform X1
100464496 PTK2; focal adhesion kinase 1 isoform X1
100480126 VAV3; guanine nucleotide exchange factor VAV3
100480092 VAV2; guanine nucleotide exchange factor VAV2
100476091 VAV1; proto-oncogene vav isoform X3
100472456 TLR6; toll-like receptor 6 isoform X2
100471801 RAP1A; ras-related protein Rap-1A
100480240 RAP1B; ras-related protein Rap-1b
100463753 CCL5; C-C motif chemokine 5
100469047 C-C motif chemokine 3
100469295 C-C motif chemokine 3 isoform X1
100464006 regakine-1-like
100463732 growth-regulated alpha protein
100466241 growth-regulated protein homolog gamma-like isoform X1
100471490 growth-regulated alpha protein
100470471 IL12A; interleukin-12 subunit alpha isoform X2
100477772 IL12B; interleukin-12 subunit beta
100468792 NLRP3; NACHT, LRR and PYD domains-containing protein 3 isoform X1
100484109 IL18; interleukin-18
100480574 HSPA5; endoplasmic reticulum chaperone BiP
100481422 ATF6; cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1
100479063 DDIT3; DNA damage-inducible transcript 3 protein
100475184 ERO1A; ERO1-like protein alpha
100467161 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X8
100475467 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2
100466256 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5
100474459 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3
100478243 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
100479743 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3
100470706 EIF2S1; eukaryotic translation initiation factor 2 subunit 1
100476284 ATF4; cyclic AMP-dependent transcription factor ATF-4
100474476 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1
100474087 TRAF2; TNF receptor-associated factor 2
100475304 MAP3K5; mitogen-activated protein kinase kinase kinase 5
100471419 XBP1; LOW QUALITY PROTEIN: X-box-binding protein 1
100483394 ABCA1; phospholipid-transporting ATPase ABCA1
100470191 ATP-binding cassette sub-family G member 1 isoform X1
117795036 ABCG1; ATP-binding cassette sub-family G member 1 isoform X1
100468118 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1
100475582 apoptosis-associated speck-like protein containing a CARD isoform X1
100471267 VLDLR; very low-density lipoprotein receptor isoform X1
100473305 PDPK1; 3-phosphoinositide-dependent protein kinase 1
100479224 GSK3B; glycogen synthase kinase-3 beta isoform X2
100470861 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X2
100464798 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X4
100477832 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1
100481755 PLCB1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
100480603 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
100465232 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
100474779 PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
100480586 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2
100478600 CALML6; calmodulin-like protein 6
100470909 CALM2; calmodulin-2
100484519 calmodulin
100484770 calmodulin-like protein 3
100481177 CALM1; calmodulin-1
100472122 CALM3; calmodulin-3
100478732 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
117799706 calmodulin-alpha-like
100477289 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
100467653 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X5
100474970 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X5
100474742 PPP3R2; calcineurin subunit B type 2
100467683 PPP3R1; calcineurin subunit B type 1
100463573 TNFSF10; tumor necrosis factor ligand superfamily member 10
105235183 tumor necrosis factor receptor superfamily member 10A-like
100479926 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
100468235 FASLG; tumor necrosis factor ligand superfamily member 6
100472842 CASP8; caspase-8 isoform X1
100465439 BID; BH3-interacting domain death agonist isoform X1
100472074 cytochrome c
105241648 cytochrome c-like
100464163 APAF1; apoptotic protease-activating factor 1 isoform X1
100483760 CASP9; caspase-9
100476854 caspase-6 isoform X2
117795025 caspase-6 isoform X1
100469056 CASP3; caspase-3 isoform X1
100471992 CASP7; caspase-7
100468516 TP53; cellular tumor antigen p53
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K14462 APOB; apolipoprotein B
K08760 APOA4; apolipoprotein A-IV
K08757 APOA1; apolipoprotein A-I
K12473 LDLR; low-density lipoprotein receptor
K08763 OLR1; oxidised low-density lipoprotein receptor 1
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K09364 POU2F; POU domain transcription factor, class 2
K09364 POU2F; POU domain transcription factor, class 2
K09364 POU2F; POU domain transcription factor, class 2
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K19722 AGER; receptor for advanced glycosylation end products
K08008 NOX1; NADPH oxidase 1
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K08011 NCF1; neutrophil cytosolic factor 1
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08010 NCF2; neutrophil cytosolic factor 2
K08012 NCF4; neutrophil cytosolic factor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K04393 CDC42; cell division control protein 42
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K14624 CCL2; C-C motif chemokine 2
K06490 ICAM1; intercellular adhesion molecule 1
K10030 IL8; interleukin 8
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K06494 SELE; selectin, endothelial cell
K06496 SELP; selectin, platelet
K06527 VCAM1; vascular cell adhesion molecule 1
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05405 IL6; interleukin 6
K03156 TNF; tumor necrosis factor superfamily, member 2
K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K26598 HSPA2; heat shock 70kDa protein 2
K09489 HSPA4; heat shock 70kDa protein 4
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K10159 TLR2; toll-like receptor 2
K05399 LBP; lipopolysaccharide-binding protein
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96; lymphocyte antigen 96
K10160 TLR4; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06259 CD36; CD36 antigen
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K10169 TLR6; toll-like receptor 6
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K05408 CCL3; C-C motif chemokine 3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K05482 IL18; interleukin 18
K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K04452 DDIT3; DNA damage-inducible transcript 3
K10950 ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K09027 XBP1; X box-binding protein 1
K05641 ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
K05679 ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K20053 VLDLR; very low-density lipoprotein receptor
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04451 TP53; tumor protein p53
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05418 Fluid shear stress and atherosclerosis [PATH:aml05418]
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05410 Hypertrophic cardiomyopathy [PATH:aml05410]
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05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:aml05412]
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05414 Dilated cardiomyopathy [PATH:aml05414]
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05415 Diabetic cardiomyopathy [PATH:aml05415]
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05416 Viral myocarditis [PATH:aml05416]
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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