Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
   Cys-loop superfamily
   Glutamate-gated cation channels
   Epithelial and related channels
   Ryanodine and IP3 receptors
   Voltage-gated cation channels
     Na+ channel, SCN alpha, NaV1.x
       voltage-gated sodium channel (SCN1A) [HSA:6323] [KO:K04833]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN2A) [HSA:6326] [KO:K04834]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN3A) [HSA:6328] [KO:K04836]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN4A) [HSA:6329] [KO:K04837]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN5A) [HSA:6331] [KO:K04838]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN8A) [HSA:6334] [KO:K04840]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN9A) [HSA:6335] [KO:K04841]
         Quinidine [ATC:C01BA01]
         Procainamide [ATC:C01BA02]
         Disopyramide [ATC:C01BA03]
         Ajmaline [ATC:C01BA05]
         Lidocaine [ATC:C01BB01 C05AD01 D04AB01]
         Mexiletine [ATC:C01BB02]
         Tocainide [ATC:C01BB03]
         Aprindine [ATC:C01BB04]
         Propafenone [ATC:C01BC03]
         Flecainide [ATC:C01BC04]
         Encainide [ATC:C01BC08]
         Moracizine [ATC:C01BG01]
         Cibenzoline [ATC:C01BG07]
         Tetracaine [ATC:C05AD02 D04AB06 N01BA03 S01HA03]
         Benzocaine [ATC:C05AD03 D02BA01 D04AB04 N01BA05 R02AD01]
         Cinchocaine [ATC:C05AD04 D04AB02 N01BB06 S01HA06]
         Procaine [ATC:C05AD05 N01BA02 S01HA05]
         Aminobenzoic acid [ATC:D02BA01]
         Chloroprocaine [ATC:N01BA04]
         Bupivacaine [ATC:N01BB01]
         Mepivacaine [ATC:N01BB03]
         Ropivacaine [ATC:N01BB09]
         Levobupivacaine [ATC:N01BB10]
         Phenytoin [ATC:N03AB02]
           D00512  Phenytoin (JP16/USP/INN)
           D02103  Phenytoin sodium (USP)
Blocker
Blocker
         Mephenytoin [ATC:N03AB04]
         Fosphenytoin [ATC:N03AB05]
         Carbamazepine [ATC:N03AF01]
         Oxcarbazepine [ATC:N03AF02]
         Eslicarbazepine [ATC:N03AF04]
         Lamotrigine [ATC:N03AX09]
         Topiramate [ATC:N03AX11]
         Zonisamide [ATC:N03AX15]
         Cocaine [ATC:N01BC01 R02AD03 S01HA01 S02DA02]
         Dyclonine [ATC:R02AD04]
         Ambroxol [ATC:R05CB06]
         Hydroquinidine
         Pilsicainide
         Pirmenol
         Proparacaine
       voltage-gated sodium channel (SCN10A) [HSA:6336] [KO:K04842]
       voltage-gated sodium channel
       sodium channel
     Ca2+ channel, CACN alpha-1, CaVx.x
     K+ channel, KCNA, Kv1.x (Shaker)
     K+ channel, KCNC, Kv3.x (Shaw)
     K+ channel, KCND, Kv4.x (Shal)
     K+ channel, KCNQ, Kv7.x (KQT-like)
     K+ channel, KCNH, Kv10-12.x (Ether-a-go-go)
     K+ channel, KCNK, K2px.x
   Related to voltage-gated cation channels
   Chloride channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
 
 Others

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Last updated: February 28, 2014

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