Target-based Classification of Drugs

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 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
     Dopamine
     Histamine
       HRH1 [HSA:3269] [KO:K04149]
         D08587  Thonzylamine (INN)
         D01801  Thonzylamine hydrochloride (JAN/USAN)
         D08183  Mepyramine (INN)
         D05660  Pyrilamine maleate (USP)
         D07194  Thenalidine (INN)
         D08645  Tripelennamine (INN)
         D02091  Tripelennamine hydrochloride (USP)
         D06246  Tripelennamine citrate
         D07195  Chloropyramine (INN)
         D07679  Chloropyramine hydrochloride
         D00494  Promethazine (JAN/INN)
         D00480  Promethazine hydrochloride (JP17/USP) <JP/US>
         D01242  Promethazine teoclate (JAN/INN)
         D03290  Promethazine methylenedisalicylate (JAN) <JP>
         D08432  Promethazine maleate
         D08768  Promethazine hibenzate <JP>
         D07196  Tolpropamine (INN)
         D07853  Dimetindene (INN)
         D01343  Dimethindene maleate (USAN)
         D03535  Clemastine (USAN)
         D00666  Clemastine fumarate (JP17/USP) <JP/US>
         D07197  Bamipine (INN)
         D07492  Bamipine dihydrochloride
         D07493  Bamipine lactate
         D08355  Pheniramine (INN)
         D01174  Pheniramine maleate (JAN/USP)
         D08091  Isothipendyl (INN)
         D01143  Isothipendyl hydrochloride (JAN)
         D00300  Diphenhydramine (JP17/INN) <JP>
         D00669  Diphenhydramine hydrochloride (JP17/USP) <JP/US>
         D02419  Diphenhydramine salicylate (JAN)
         D03285  Diphenhydramine tannate (JP17)
         D03360  Diphenhydramine laurylsulfate (JAN) <JP>
         D03854  Diphenhydramine citrate (USP)
         D07198  Chlorphenoxamine (INN)
         D07684  Chlorphenoxamine hydrochloride
         D00774  Orphenadrine citrate (USP) <US>
         D07854  Dimetotiazine (INN)
         D01902  Fonazine mesylate (USAN) <JP>
         D02599  Orphenadrine hydrochloride
         D00270  Chlorpromazine (USP/INN)
         D00789  Chlorpromazine hydrochloride (JP17/USP) <JP/US>
         D03274  Chlorpromazine hibenzate (JAN)
         D04034  Chlorpromazine phenolphthalinate (JAN) <JP>
         D09819  Chlorpromazine tannate (JAN)
         D00454  Olanzapine (JAN/USAN/INN) <JP/US>
         D06623  Olanzapine pamoate (USAN) <US>
         D08054  Hydroxyzine (INN)
         D00672  Hydroxyzine hydrochloride (JP17/USP) <JP/US>
         D01096  Hydroxyzine pamoate (JP17/USP) <JP/US>
         D08297  Opipramol (INN)
         D01477  Opipramol hydrochloride (JAN/USAN)
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D07522  Betahistine (INN)
         D01592  Betahistine mesilate (JP17) <JP>
         D03102  Betahistine hydrochloride (USP)
         D01295  Cinnarizine (JAN/USAN/INN)
         D07734  Cinnarizine dihydrochloride
         D08117  Levocabastine (INN)
         D01717  Levocabastine hydrochloride (JAN/USAN) <JP>
         D07483  Azelastine (INN)
         D00659  Azelastine hydrochloride (JP17/USAN) <JP/US>
         D07458  Antazoline (INN)
         D02950  Antazoline phosphate (USP)
         D07459  Antazoline hydrochloride
         D08293  Olopatadine (INN) <US>
         D01192  Olopatadine hydrochloride (JP17/USAN) <JP/US>
         D03166  Bromodiphenhydramine hydrochloride (USP)
         D07862  Diphenylpyraline (INN)
         D01172  Diphenylpyraline hydrochloride (JAN)
         D01627  Diphenylpyraline teoclate (JAN)
         D07617  Carbinoxamine (INN)
         D01336  Carbinoxamine maleate (JAN/USP) <US>
         D09808  Carbinoxamine diphenyldisulfonate (JAN)
         D07878  Doxylamine (INN)
         D02327  Doxylamine succinate (USP)
         D07543  Brompheniramine (INN)
         D00663  Brompheniramine maleate (USAN)
         D07803  Dexchlorpheniramine (INN)
         D00668  Dexchlorpheniramine maleate (USP) <JP>
         D07398  Chlorphenamine (INN)
         D00665  Chlorpheniramine maleate (JP17/USP) <JP>
         D03475  Chlorpheniramine polistirex (USAN)
         D03704  Dexbrompheniramine maleate (USAN)
         D07125  Alimemazine (INN)
         D02245  Trimeprazine tartrate (USP) <JP>
         D04979  Methdilazine (INN)
         D04980  Methdilazine hydrochloride (USP)
         D01324  Mequitazine (JP17/INN) <JP>
         D07401  Oxomemazine (INN)
         D07547  Buclizine (INN)
         D02089  Buclizine hydrochloride (USAN)
         D03621  Cyclizine (INN)
         D02090  Cyclizine lactate (BAN)
         D03622  Cyclizine hydrochloride (USP)
         D08163  Meclozine (BAN)
         D01317  Meclizine hydrochloride (JAN/USP) <US>
         D07662  Cetirizine (INN)
         D00664  Cetirizine hydrochloride (JP17/USAN) <JP/US>
         D07402  Levocetirizine (USAN/INN)
         D08118  Levocetirizine dihydrochloride (USAN) <JP/US>
         D07765  Cyproheptadine (INN)
         D02234  Cyproheptadine hydrochloride (JP17/USP) <JP/US>
         D08353  Phenindamine (INN)
         D02148  Phenindamine tartrate (USAN)
         D08648  Triprolidine (INN)
         D01782  Triprolidine hydrochloride (USP)
         D07403  Pyrrobutamine (BAN)
         D07482  Azatadine (INN)
         D00662  Azatadine maleate (USP)
         D00234  Astemizole (JAN/USP/INN)
         D00521  Terfenadine (JAN/USAN/INN)
         D00364  Loratadine (JAN/USAN/INN) <JP/US>
         D08161  Mebhydrolin (INN)
         D01786  Mebhydrolin napadisilate (JAN)
         D07404  Deptropine (INN)
         D07790  Deptropine citrate
         D08105  Ketotifen (INN)
         D01332  Ketotifen fumarate (JP17/USAN) <JP>
         D02760  Acrivastine (USAN/INN)
         D01478  Ebastine (JP17/USAN/INN) <JP>
         D07406  Pimethixene (INN)
         D07900  Epinastine (INN)
         D01713  Epinastine hydrochloride (JAN) <JP/US>
         D01117  Mizolastine (JAN/INN)
         D07958  Fexofenadine (INN)
         D00671  Fexofenadine hydrochloride (JP17/USAN) <JP/US>
         D03693  Desloratadine (JAN/USAN/INN) <JP/US>
         D07407  Rupatadine (INN)
         D08497  Rupatadine fumarate (JAN) <JP>
         D09570  Bilastine (JAN/INN) <JP>
         D10230  Quifenadine (INN)
         D10510  Sequifenadine
         D07890  Emedastine (INN)
         D02249  Emedastine difumarate (JP17/USP) <JP/US>
         D06552  Alcaftadine (JAN/USAN/INN) <US>
         D00520  Dimenhydrinate (JP17/USP/INN) <JP/US>
         D01460  Homochlorcyclizine hydrochloride (JP17) <JP>
         D01654  Bepotastine besylate (USAN) <JP/US>
         D01705  Clemizole hydrochloride (JAN)
         D02013  Clemizole undecylate (JAN)
         D02067  Diphenylimidazole (JAN)
         D03491  Cidoxepin hydrochloride (USAN)
         D04494  Icotidine (USAN)
         D05196  Noberastine (USAN/INN)
         D05742  Rocastine hydrochloride (USAN)
         D06012  Tazifylline hydrochloride (USAN)
         D06021  Tecastemizole (USAN/INN)
         D06063  Temelastine (USAN/INN)
         D07860  Dioxopromethazine hydrochloride
         D07889  Embramine (INN)
         D08040  Histamine (DCF)
         D08041  Homochlorcyclizine (INN)
         D08305  Orphenadrine (INN)
         D09705  Bepotastine (USAN/INN)
       HRH2 [HSA:3274] [KO:K04150]
       HRH3 [HSA:11255] [KO:K04151]
       HRH4 [HSA:59340] [KO:K04152]
     Serotonin
     Tachykinin
     Ghrelin
     Orexin
     Neuropeptide Y
     Opioid
     Angiotensin
     Bradykinin
     Endothelin
     Lutropin-choriogonadotropic hormone
     Follicle stimulating hormone
     Oxytocin
     Vasopressin
     Melanocortin
     Gonadotropin-releasing hormone
     Somatostatin
     Thyrotropin-releasing hormone
     Cholecystokinin
     Motilin
     Thrombin
     Purine / pyrimidine
     Adenosine
     Prostaglandin
     Prostacyclin
     Leukotriene
     Thromboxane
     Sphingolipid
     Free fatty acid
     Cannabinoid
     Platelet activating factor
     Melatonin
     Cysteinyl leukotriene
   Secretin receptor family
   Metabotropic glutamate receptor family
 
 Ion channels
   Ligand-gated ion channels
   Voltage-gated ion channels
     Sodium channels
     Calcium channels
     Pottasium channels
       KCNA1 [HSA:3736] [KO:K04874]
       KCNA5 [HSA:3741] [KO:K04878]
       KCNA7 [HSA:3743] [KO:K04880]
       KCND [HSA:3750 3751 3752] [KO:K04891 K04892 K04893]
       KCND3 [HSA:3752] [KO:K04893]
       KCNH2 [HSA:3757] [KO:K04905]
         D02910  Amiodarone (USAN/INN)
         D00636  Amiodarone hydrochloride (JP17/USAN) <JP/US>
         D00647  Dofetilide (JAN/USAN/INN) <US>
         D08060  Ibutilide (INN)
         D00648  Ibutilide fumarate (USAN) <US>
         D02537  Dronedarone (INN)
         D03914  Dronedarone hydrochloride (USAN) <US>
         D08525  Sotalol (INN)
         D01026  Sotalol hydrochloride (JAN/USP) <JP/US>
         D07520  Bepridil (INN)
         D00631  Bepridil hydrochloride (USAN) <JP>
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D00521  Terfenadine (JAN/USAN/INN)
         D01856  Nifekalant hydrochloride (JAN) <JP>
         D03037  Azimilide dihydrochloride (USAN)
         D03547  Clofilium phosphate (USAN/INN)
         D03732  Dexsotalol hydrochloride (USAN)
         D04955  Sematilide hydrochloride (USAN)
         D06206  Trecetilide fumarate (USAN)
         D09757  Terikalant (INN)
         D09758  Ambasilide (INN)
         D09759  Trecetilide (INN)
       KCNQ [HSA:3784 3785 3786 9132 56479] [KO:K04926 K04927 K04928 K04929 K04930]
       KCNQ1 [HSA:3784] [KO:K04926]
       KCNMB1 [HSA:3779] [KO:K04937]
       KCNN4 [HSA:3783] [KO:K04945]
     Inward rectifier channels (Kir)
     Ryanodine receptors (RYR)
     Transient receptor potential channels
   Other ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
 
 Not elsewhere classified

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Last updated: May 25, 2018

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