Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
       alpha1a-adrenergic receptor [HSA:148] [KO:K04135]
       alpha1-adrenergic receptor [HSA:148 147 146] [KO:K04135 K04136 K04137]
         Epinephrine [DG:DG00013]
         Adrenalone [DG:DG00016]
         Amiodarone [DG:DG00204]
         Quinidine [DG:DG00192]
         Etilefrine [DG:DG00210]
         Norepinephrine [DG:DG00212]
         Norfenefrine [DG:DG00214]
         Phenylephrine [DG:DG00215]
         Dobutamine [DG:DG00216]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Methoxamine [DG:DG00219]
         Midodrine [DG:DG00224]
         Ephedrine [DG:DG00227]
         Prazosin [DG:DG00253]
         Indoramin [DG:DG00254]
         Trimazosin [DG:DG00255]
         Doxazosin [DG:DG00256]
         Urapidil [DG:DG00257]
         Ketanserin [DG:DG00265]
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Nicergoline [DG:DG00283]
         Phenoxybenzamine [DG:DG00285]
         Moxisylyte [DG:DG00287]
         Ifenprodil [DG:DG00292]
         Bevantolol [DG:DG02494]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Methylergometrine [DG:DG00445]
         Ergometrine [DG:DG00446]
         Alfuzosin [DG:DG00489]
         Tamsulosin [DG:DG00490]
         Terazosin [DG:DG00491]
         Dihydroergotamine [DG:DG00833]
         Ergotamine [DG:DG00834]
         Levomepromazine [DG:DG00868]
         Droperidol [DG:DG02601]
         Pimozide [DG:DG02471]
         Propericiazine [DG:DG02610]
         Sertindole [DG:DG02473]
         Olanzapine [DG:DG00898]
         Quetiapine [DG:DG00899]
         Risperidone [DG:DG02472]
         Mianserin [DG:DG00951]
         Oxymetazoline [DG:DG01029]
         Tetryzoline [DG:DG01030]
         Xylometazoline [DG:DG01031]
         Naphazoline [DG:DG01032]
         Tramazoline [DG:DG01033]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine [DG:DG01129]
         Dapiprazole [DG:DG01140]
         Methylephedrine [DG:DG01229]
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP17)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Setiptiline [DG:DG01231]
         Amosulalol [DG:DG01302]
         Arotinolol [DG:DG01303]
         Bunazosin [DG:DG01316]
         Medroxalol [DG:DG01317]
         Amidephrine [DG:DG02432]
         Bunitrolol [DG:DG02464]
         Guanadrel [DG:DG02468]
         Naftopidil [DG:DG02469]
         Pelanserin [DG:DG02470]
         Nipradilol [DG:DG02533]
       alpha2a-adrenergic receptor [HSA:150] [KO:K04138]
       alpha2b-adrenergic receptor [HSA:151] [KO:K04139]
       alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
         Epinephrine [DG:DG00013]
         Norepinephrine [DG:DG00212]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Ephedrine [DG:DG00227]
         Methyldopa (levorotatory) [DG:DG00248]
         Clonidine [DG:DG00249]
         Rilmenidine [DG:DG02489]
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Phenoxybenzamine [DG:DG00285]
         Brimonidine [DG:DG00442]
         Methylergometrine [DG:DG00445]
         Ergometrine [DG:DG00446]
         Yohimbin [DG:DG00485]
         Tizanidine [DG:DG00773]
         Piribedil [DG:DG02488]
         Chlorpromazine [DG:DG00867]
         Levomepromazine [DG:DG00868]
         Clozapine [DG:DG02476]
         Quetiapine [DG:DG00899]
         Asenapine [DG:DG02427]
         Dexmedetomidine [DG:DG00926]
         Mianserin [DG:DG00951]
         Mirtazapine [DG:DG02487]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine [DG:DG01129]
         Dapiprazole [DG:DG01140]
         Methylephedrine [DG:DG01229]
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP17)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Tramazoline [DG:DG01033]
         Apraclonidine [DG:DG01130]
         Setiptiline [DG:DG01231]
         Detomidine [DG:DG01318]
         Guanabenz [DG:DG01319]
         Medetomidine [DG:DG01320]
         Xylazine [DG:DG01321]
         Guanadrel [DG:DG02468]
         Aptazapine [DG:DG02474]
         Atipamezole [DG:DG02475]
         Delequamine [DG:DG02477]
         Fluparoxan [DG:DG02485]
         Levonordefrin [DG:DG02486]
         Romifidine [DG:DG02490]
       beta1-adrenergic receptor [HSA:153] [KO:K04141]
         Amiodarone [DG:DG00204]
         Propafenone [DG:DG00200]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Dobutamine [DG:DG00216]
         Prenalterol [dg:DG00221]
         Dopexamine [DG:DG00222]
         Ephedrine [DG:DG00227]
         Xamoterol [DG:DG00231]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Propranolol [DG:DG00305]
         Timolol [DG:DG00306]
         Sotalol [DG:DG00307]
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Practolol [DG:DG02534]
         Metoprolol [DG:DG00313]
         Atenolol [DG:DG02492]
         Acebutolol [DG:DG00314]
         Betaxolol [DG:DG00315]
         Bevantolol [DG:DG02494]
         Bisoprolol [DG:DG00316]
         Celiprolol [DG:DG00317]
         Esmolol [DG:DG00318]
         Epanolol [DG:DG02517]
         Esatenolol [DG:DG02493]
         Nebivolol [DG:DG00319]
         Talinolol [DG:DG02539]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine [DG:DG01129]
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol [DG:DG01138]
         Methylephedrine [DG:DG01229]
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP17)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Amosulalol [DG:DG01302]
         Arotinolol [DG:DG01303]
         Medroxalol [DG:DG01317]
         Tilisolol [DG:DG01322]
         Indenolol [DG:DG01323]
         Bucumolol [DG:DG02503]
         Butopamine [DG:DG02510]
         Denopamine [DG:DG02514]
         Landiolol [DG:DG02529]
         Levdobutamine [DG:DG02530]
         Levobetaxolol [DG:DG02531]
       beta2-adrenergic receptor [HSA:154] [KO:K04142]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Dobutamine [DG:DG00216]
         Dopexamine [DG:DG00222]
         Ephedrine [DG:DG00227]
         Isoxsuprine [DG:DG00277]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Propranolol [DG:DG00305]
         Timolol [DG:DG00306]
         Sotalol [DG:DG00307]
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Ritodrine [DG:DG00450]
         Fenoterol [DG:DG00451]
         Pseudoephedrine [DG:DG01042]
         Methoxyphenamine [DG:DG02541]
         Orciprenaline [DG:DG01044]
         Albuterol [DG:DG01045]
         Terbutaline [DG:DG01046]
         Hexoprenaline [DG:DG01047]
         Rimiterol [DG:DG02545]
         Pirbuterol [DG:DG01048]
         Tretoquinol [DG:DG01049]
         Carbuterol [DG:DG02520]
         Tulobuterol [DG:DG01050]
         Salmeterol [DG:DG01051]
         Formoterol [DG:DG01052]
         Clenbuterol [DG:DG01053]
         Reproterol [DG:DG01054]
         Procaterol [DG:DG01055]
         Bitolterol [DG:DG01056]
         Indacaterol [DG:DG01057]
         Olodaterol [DG:DG01058]
         Bambuterol [DG:DG01060]
         Dipivefrine[DG:DG01129]
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol [DG:DG01138]
         Methylephedrine [DG:DG01229]
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP17)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Abediterol [DG:DG01232]
         Arformoterol [DG:DG01233]
         Isoetharine [DG:DG01234]
         Levalbuterol [DG:DG01235]
         Vilanterol [DG:DG01236]
         Amosulalol [DG:DG01302]
         Arotinolol [DG:DG01303]
         Medroxalol [DG:DG01317]
         Tilisolol [DG:DG01322]
         Indenolol [DG:DG01323]
         Batefenterol [DG:DG01627]
         Bucumolol [DG:DG02503]
         Butoxamine [DG:DG02519]
         Carazolol [DG:DG02523]
         Clorprenaline [DG:DG02524]
         Colterol [DG:DG02525]
         Levosalbutamol [DG:DG02526]
         Mabuterol [DG:DG02527]
         Metaproterenol [DG:DG02540]
         Milveterol [DG:DG02542]
         Picumeterol [DG:DG02543]
         Ractopamine [DG:DG02544]
         Sibenadet [DG:DG02546]
         Soterenol [DG:DG02547]
         Zinterol [DG:DG02548]
       beta3-adrenergic receptor [HSA:155] [KO:K04143]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Ephedrine [DG:DG00227]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Propranolol [DG:DG00305]
         Timolol [DG:DG00306]
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Mirabegron [DG:DG02555]
         Pseudoephedrine [DG:DG01042]
         Dipivefrin [DG:DG01129]
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol [DG:DG01138]
         Methylephedrine [DG:DG01229]
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP17)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Amibegron [DG:DG01237]
         Amosulalol [DG:DG01302]
         Arotinolol [DG:DG01303]
         Medroxalol [DG:DG01317]
         Tilisolol [DG:DG01322]
         Talibegron [DG:DG02538]
         Fasobegron [DG:DG02554]
         Ritobegron [DG:DG02556]
         Solabegron [DG:DG02557]
         Vibegron [DG:DG02558]
       beta-adrenergic receptor [HSA:153 154 155] [KO:K04141 K04142 K04143]
     Dopamine
     Histamine
     Serotonin
     Tachykinin / neurokinin
     Ghrelin
     Orexin
     Neuropeptide Y
     Opioid
     Angiotensin
     Bradykinin
     Endothelin
     Lutropin-choriogonadotropic hormone
     Follicle stimulating hormone
     Oxytocin
     Vasopressin
     Melanocortin
     Gonadotropin-releasing hormone
     Somatostatin
     Thyrotropin-releasing hormone
     Cholecystokinin
     Motilin
     Thrombin
     Purine / pyrimidine
     Adenosine
     Prostaglandin
     Prostacyclin
     Leukotriene
     Thromboxane
     Sphingolipid
     Free fatty acid
     Cannabinoid
     Platelet activating factor
     Melatonin
     Cysteinyl leukotriene
   Secretin receptor family
   Metabotropic glutamate receptor family
   Others
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
 
 Others

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Last updated: November 20, 2017

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