Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
   Class I cytokines
   Class II cytokines
   PDGF family
   TNF family
     TNF-alpha [HSA:7124] [KO:K03156]
       Lenalidomide [DG:DG00744]
       Infliximab [DG:DG02648]
         D02598  Infliximab (USAN/INN)
Monoclonal antibody
       Adalimumab [DG:DG02665]
       Afelimomab [DG:DG02744]
       Certolizumab [DG:DG02745]
       Etanercept [DG:DG02746]
       Golimumab [DG:DG02770]
       Lenercept
       Nerelimomab
       Onercept
       Ozoralizumab
       Pegsunercept
       Placulumab
     LTA [HSA:4049] [KO:K05468]
     LTB [HSA:4050] [KO:K03157]
     Lymphotoxin [HSA:4049 4050] [KO:K05468 K03157]
     TNFSF4 (OX40L) [HSA:7292] [KO:K05469]
     CD40L (CD154) [HSA:959] [KO:K03161]
     CD70 [HSA:970] [KO:K05470]
     RANKL [HSA:8600] [KO:K05473]
     APRIL [HSA:8741] [KO:K05475]
     BAFF [HSA:10673] [KO:K05476]
   IL-1 family
   IL-17 family
   TGF-beta family
   Chemokines
 
 Monoclonal antibody
   CD2 [HSA:914] [KO:K06449]
   CD3 [HSA:915 916 917] [KO:K06450 K06451 K06452]
   CD4 [HSA:920] [KO:K06454]
   CD5 [HSA:921] [KO:K06455]
   CD11A [HSA:3683] [KO:K05718]
   CD11A/CD18 (LFA-1) [HSA:3683 3689] [KO:K05718 K06464]
   CD11B/CD18 (Mac-1) [HSA:3684 3689] [KO:K06461 K06464]
   CD19 [HSA:930] [KO:K06465]
   CD20 [HSA:931] [KO:K06466]
   CD22 [HSA:933] [KO:K06467]
   CD23 (FCER2) [HSA:2208] [KO:K06468]
   CD25 [HSA:3559] [KO:K05068]
   CD30 (TNFRSF8) [HSA:943] [KO:K05145]
   CD33 [HSA:945] [KO:K06473]
   CD40 (TNFRSF5) [HSA:958] [KO:K03160]
   CD40L (CD154) [HSA:959] [KO:K03161]
   CD49d (integrin alpha4) [HSA:3676] [KO:K06483]
   CD51 (integrin alphaV) [HSA:3685] [KO:K06487]
   CD52 [HSA:1043] [KO:K06488]
   CD54 (ICAM-1) [HSA:3383] [KO:K06490]
   CD56 (NCAM) [HSA:4684] [KO:K06491]
   CD62P [HSA:6403] [KO:K06496]
   CD66 (CEACAM) [HSA:1048 1084 1087 1088 1089 4680 634 90273] [KO:K06499]
   CD70 [HSA:970] [KO:K05470]
   CD74 [HSA:972] [KO:K06505]
   CD80 [HSA:941] [KO:K05412]
   CD125 [HSA:3568] [KO:K05067]
   CD126 [HSA:3570] [KO:K05055]
   CD137 (TNFRSF9) [HSA:3604] [KO:K04060]
   CD152 (CTLA4) [HSA:1493] [KO:K06538]
   CD158 (killer-cell immunoglobulin-like receptor, two domains) [HSA:3802 3803 3804 3805 57292 553128 3806 100132285 3808 3809 3810] [KO:K07981 K07982]
   CD200 [HSA:4345] [KO:K06556]
   CD217 (interleukin 17 receptor) [HSA:23765] [KO:K05164]
   CD221 (insulin-like growth factor 1 receptor) [HSA:3480] [KO:K05087]
   CD227 [HSA:4582] [KO:K06568]
   CD261 (TNFRSF10A) [HSA:8797] [KO:K04722]
   CD262 (TNFRSF10B) [HSA:8795] [KO:K04722]
   CD266 (TNFRSF12A) [HSA:51330] [KO:K05149]
   CD279 [HSA:5133] [KO:K06744]
   CD304 [HSA:8829] [KO:K06724]
   CD319 (CS1) [HSA:57823] [KO:K06733]
   CD326 (EpCAM) [HSA:4072] [KO:K06737]
   CD274 (PDL1) [HSA:29126] [KO:K06745]
   TNF-alpha [HSA:7124] [KO:K03156]
     Lenalidomide [DG:DG00744]
     Infliximab [DG:DG02648]
       D02598  Infliximab (USAN/INN)
 
     Adalimumab [DG:DG02665]
     Afelimomab [DG:DG02744]
     Certolizumab [DG:DG02745]
     Golimumab [DG:DG02770]
     Nerelimomab
     Ozoralizumab
     Placulumab
   delta-like 4 (DLL4) [HSA:54567] [KO:K06051]
   CA125 [HSA:94025] [KO:K16145]
   HLA-DR beta [HSA:3123 3125 3126 3127] [KO:K06752]
   VEGFA [HSA:7422] [KO:K05448]
   C5 [HSA:727] [KO:K03994]
   protective antigen (PA) [KO:K11030]
   EGFR tyrosine kinase [HSA:1956] [KO:K04361]
   VEGFR2 tyrosine kinase [HSA:3791] [KO:K05098]
   prostate-specific membrane antigen (PSMA) [HSA:2346] [KO:K14592]
   carbonic anhydrase 9 [HSA:768] [KO:K01672]
   proprotein convertase subtilisin/kexin type 9 (PCSK9) [HSA:255738] [KO:K13050]
   interleukin 5 [HSA:3567] [KO:K05428]
   interleukin 6 [HSA:3569] [KO:K05405]
   interleukin 9 [HSA:3578] [KO:K05432]
   interleukin 12 [HSA:3592 3593] [KO:K05406 K05425]
   interleukin 13 [HSA:3596] [KO:K05435]
   interleukin 23 subunit alpha [HSA:51561] [KO:K05426]
   interferon alpha [HSA:3439 3440 3441 3442 3443 3444 3445 3446 3447 3448 3449 3451 3452] [KO:K05414]
   interferon gamma [HSA:3458] [KO:K04687]
   NGF [HSA:4803] [KO:K02582]
   HGF [HSA:3082] [KO:K05460]
   LTA [HSA:4049] [KO:K05468]
   TNFSF4 (OX40L) [HSA:7292] [KO:K05469]
   BAFF [HSA:10673] [KO:K05476]
   IL-22 [HSA:50616] [KO:K05445]
   C-C motif chemokine 2 [HSA:6347] [KO:K14624]
   IgE
   GD2 [GL:G00114]
   integrin alpha2B/beta 3 [HSA:3674 3690] [KO:K06476 K06493]
   integrin alpha4/beta7 [HSA:3676 3695] [KO:K06483 K06590]
   integrin alpha5/beta1 (VLA-5) [HSA:3678 3688] [KO:K06484 K05719]
   integrin alphaV/beta3 (VNR) [HSA:3685 3690] [KO:K06487 K06493]
   integrin alphaE/beta7 [HSA:3682 3695] [KO:K06524 K06590]
 
 Others

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Last updated: January 10, 2018

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