Target-based Classification of Drugs

[ Brite menu | Download htext ]
    

1st Level  2nd Level  3rd Level  4th Level  5th Level  6th Level 

     Remark
 G Protein-coupled receptors
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
   Oxidoreductases
   Transferases
   Hydrolases
     pancreatic lipase [HSA:5406 5407 5408] [KO:K14073 K14074 K14075]
     bile salt-stimulated lipase inhibitor [HSA:1056] [KO:K12298]
     secretory phospholipase A2 (PLA2) [HSA:26279 30814 391013 50487 5319 5320 5322 64600 81579 8399 84647] [KO:K01047]
     cytosolic phospholipase A2-alpha (cPLA2-alpha) [HSA:5321] [KO:K16342]
     acetylcholinesterase (AChE) [HSA:43] [KO:K01049]
     butyrylcholinesterase (BChE) [HSA:590] [KO:K01050]
     lipoprotein lipase [HSA:4023] [KO:K01059]
     lipoprotein-associated phospholipase A2 (LP-PLA2) [HSA:7941]
     calcineurin [HSA:5530 5532 5533 5534 5535 11261 63928] [KO:K04348 K06268]
     protein tyrosine phosphatase, non-receptor type 1 (PTP1B) [HSA:5777] [KO:K05697]
     phosphodiesterase (PDE) [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K01120 K13296 K13298 K13755]
     phosphodiesterase (PDE) III [HSA:5139 5140] [KO:K13296]
     phosphodiesterase (PDE) IV [HSA:5141 5142 5143 5144] [KO:K01120]
     phosphodiesterase (PDE) V [HSA:8654] [KO:K13762]
     steroid sulfatase [HSA:412] [KO:K01131]
     alpha-amylase [HSA:279 280] [KO:K01176]
     alpha-glucosidase [HSA:2548 2595 8972] [KO:K12316 K12317 K12047]
     aminopeptidase N [HSA:290] [KO:K11140]
     aminopeptidase B [HSA:6051] [KO:K01260]
     renal dehydropeptidase I [HSA:1800] [KO:K01273]
     dipeptidyl-peptidase 4 (DPP4) [HSA:1803] [KO:K01278]
     angiotensin-converting enzyme (ACE) [HSA:1636] [KO:K01283]
     alpha-chymotrypsin [HSA:1504 440387] [KO:K01310]
     trypsin [HSA:5644 5645 5646] [KO:K01312]
     thrombin [HSA:2147] [KO:K01313]
     factor Xa [HSA:2159] [KO:K01314]
     plasmin [HSA:5340] [KO:K01315]
     coagulation factor IX [HSA:2158] [KO:K01321]
     coagulation factor VIII [HSA:2157] [KO:K03899]
     plasma kallikrein [HSA:3818] [KO:K01324]
     tissue kallikrein [HSA:3816 3817] [KO:K01325]
     leukocyte elastase [HSA:1991] [KO:K01327]
     protein C [HSA:5624] [KO:K01344]
     proprotein convertase subtilisin/kexin type 9 (PCSK9) [HSA:255738] [KO:K13050]
     caspase 1 (CASP1) [HSA:834] [KO:K01370]
     cathepsin K [HSA:1513] [KO:K01371]
     renin [HSA:5972] [KO:K01380]
     neutral endopeptidase [HSA:4311] [KO:K01389]
       Candoxatril
       Candoxatrilat
       Ecadotril
         D03929  Ecadotril (USAN/INN)
Inhibitor
     matrix metalloproteinase 1 [HSA:4312] [KO:K01388]
     matrix metalloproteinase 2 [HSA:4313] [KO:K01398]
     matrix metalloproteinase 3 [HSA:4314] [KO:K01394]
     matrix metalloproteinase 8 [HSA:101] [KO:K06540]
     matrix metalloproteinase 9 [HSA:4318] [KO:K01403]
     matrix metalloproteinase 13 [HSA:4322] [KO:K07994]
     matrix metalloproteinase 14 [HSA:4323] [KO:K07763]
     matrix metalloproteinase
     ADAM10 (CD156c) [HSA:102] [KO:K06704]
     ADAM17 (CD156B) [HSA:6868] [KO:K06059]
     proteasome subunit beta type-1 (PSMB1) [HSA:5689] [KO:K02732]
     proteasome subunit beta type-2 (PSMB2) [HSA:5690] [KO:K02734]
     proteasome subunit beta type-5 (PSMB5) [HSA:5693] [KO:K02737]
     urease [KO:K01428 K01429 K01430 K14048]
     histone deacetylase [HSA:3065 3066 8841 9759 10014 10013 51564 55869 9734 83933] [KO:K06067 K11404 K11405 K11406 K11407 K11408 K11409]
     histone deacetylase 1 (HDAC1) [HSA:3065] [KO:K06067]
     histone deacetylase 2 (HDAC2) [HSA:3066] [KO:K06067]
     histone deacetylase 3 (HDAC3) [HSA:8841] [KO:K11404]
     histone deacetylase 6 (HDAC6) [HSA:10013] [KO:K11407]
     adenosine deaminase [HSA:100] [KO:K01488]
     sodium/potassium-transporting ATPase [HSA:476 477 478 480 23439 481 482 483] [KO:K01539 K01540]
     H+/K+ exchanging, polypeptide [HSA:495 496] [KO:K01542 K01543]
     P-glycoprotein [HSA:5243] [KO:K05658]
     prostate-specific membrane antigen (PSMA) [HSA:2346] [KO:K14592]
   Lyases
   Isomerases
 
 Protein kinases
 
 Cytokines
 
 Others

[ DRUG | BRITE | KEGG2 | KEGG ]
Last updated: November 7, 2014

» Japanese version