Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
   Class I cytokines
   Class II cytokines
   PDGF family
   TNF family
     TNF-alpha [HSA:7124] [KO:K03156]
       Lenalidomide [DG:DG00744]
       Infliximab
       Adalimumab
       Afelimomab
         D07436  Afelimomab (INN)
Monoclonal antibody
       Certolizumab
       Etanercept [DG:DG02746]
       Golimumab
       Lenercept
       Nerelimomab
       Onercept
       Ozoralizumab
       Pegsunercept
       Placulumab
     LTA [HSA:4049] [KO:K05468]
     LTB [HSA:4050] [KO:K03157]
     Lymphotoxin [HSA:4049 4050] [KO:K05468 K03157]
     TNFSF4 (OX40L) [HSA:7292] [KO:K05469]
     CD40L (CD154) [HSA:959] [KO:K03161]
     CD70 [HSA:970] [KO:K05470]
     RANKL [HSA:8600] [KO:K05473]
     APRIL [HSA:8741] [KO:K05475]
     BAFF [HSA:10673] [KO:K05476]
   IL-1 family
   IL-17 family
   TGF-beta family
   Chemokines
 
 Monoclonal antibodies
   CD2 [HSA:914] [KO:K06449]
   CD3 [HSA:915 916 917] [KO:K06450 K06451 K06452]
   CD4 [HSA:920] [KO:K06454]
   CD5 [HSA:921] [KO:K06455]
   ITGAL (CD11a) [HSA:3683] [KO:K05718]
   ITGAM (CD11b) [HSA:3684] [KO:K06464]
   ITGB2 (CD18) [HSA:3689] [KO:K06464]
   CD19 [HSA:930] [KO:K06465]
   CD20 [HSA:931] [KO:K06466]
   CD22 [HSA:933] [KO:K06467]
   CD23 (FCER2) [HSA:2208] [KO:K06468]
   CD25 (IL2RA) [HSA:3559] [KO:K05068]
   CD30 (TNFRSF8) [HSA:943] [KO:K05145]
   CD33 [HSA:945] [KO:K06473]
   CD38 [HSA:952] [KO:K01242]
   TNFRSF5 (CD40) [HSA:958] [KO:K03160]
   ITGA2B (CD41) / ITGB3 (CD61) [HSA:3674 3690] [KO:K06476 K06493]
   ITGA4 (CD49d) [HSA:3676] [KO:K06483]
   ITGA4 (CD49d) / ITGB7 [HSA:3676 3695] [KO:K06483 K06590]
   ITGA5 (CD49e) / ITGB1 (CD29) [HSA:3678 3688] [KO:K06484 K05719]
   ITGAV (CD51) [HSA:3685] [KO:K06487]
   ITGAV (CD51) / ITGB3 (CD61) [HSA:3685 3690] [KO:K06487 K06493]
   CD52 [HSA:1043] [KO:K06488]
   ICAM1 (CD54) [HSA:3383] [KO:K06490]
   NCAM1 (CD56) [HSA:4684] [KO:K06491]
   SELP (CD62P) [HSA:6403] [KO:K06496]
   CEACAM (CD66) [HSA:1048 1084 1087 1088 1089 4680 634 90273] [KO:K06499]
   CD70 [HSA:970] [KO:K05470]
   CD74 [HSA:972] [KO:K06505]
   CD80 [HSA:941] [KO:K05412]
   ITGAE (CD103) /ITGB7 [HSA:3682 3695] [KO:K06524 K06590]
   IL5RA (CD125) [HSA:3568] [KO:K05067]
   IL6R (CD126) [HSA:3570] [KO:K05055]
   TNFRSF9 (CD137) [HSA:3604] [KO:K05146]
   CTLA4 (CD152) [HSA:1493] [KO:K06538]
   TNFSF5 (CD154) [HSA:959] [KO:K03161]
   KIR2DL (CD158) [HSA:3802 3803 3804] [KO:K07981]
   CD200 [HSA:4345] [KO:K06556]
   IL17RA (CD217) [HSA:23765] [KO:K05164]
   IGF1R (CD221) [HSA:3480] [KO:K05087]
   MUC1 (CD227) [HSA:4582] [KO:K06568]
   OX40L (TNFSF4, CD252) [HSA:7292] [KO:K05469]
   BAFF (TNFSF13B, CD257) [HSA:10673] [KO:K05476]
   TNFRSF10A (TRAILR1, CD261) [HSA:8797] [KO:K04722]
   TNFRSF10B (TRAILR2, CD262) [HSA:8795] [KO:K04722]
   TNFRSF12A (TWEAKR, CD266) [HSA:51330] [KO:K05149]
   PDL1 (CD274) [HSA:29126] [KO:K06745]
   PDCD1 (PD1, CD279) [HSA:5133] [KO:K06744]
   NRP1 (CD304) [HSA:8829] [KO:K06724]
   SLAMF7 (CD319) [HSA:57823] [KO:K06733]
   EPCAM (CD326) [HSA:4072] [KO:K06737]
   ERBB2 (HER2, CD340) [HSA:2064] [KO:K05083]
   TNF (TNFA, TNFSF2) [HSA:7124] [KO:K03156]
     Lenalidomide
     Infliximab
     Adalimumab
     Afelimomab
       D07436  Afelimomab (INN)
 
     Certolizumab
     Golimumab
     Nerelimomab
     Ozoralizumab
     Placulumab
   DLL4 [HSA:54567] [KO:K06051]
   MUC16 (CA125) [HSA:94025] [KO:K16145]
   HLA-DRB [HSA:3123 3125 3126 3127] [KO:K06752]
   VEGFA [HSA:7422] [KO:K05448]
   C5 [HSA:727] [KO:K03994]
   EGFR [HSA:1956] [KO:K04361]
   PDGFRA [HSA:5156] [KO:K04363]
   VEGFR2 (KDR) [HSA:3791] [KO:K05098]
   MET [HSA:4233] [KO:K05099]
   FOLH1 [HSA:2346] [KO:K14592]
   CA9 [HSA:768] [KO:K01672]
   PCSK9 [HSA:255738] [KO:K13050]
   IL5 [HSA:3567] [KO:K05428]
   IL6 [HSA:3569] [KO:K05405]
   IL9 [HSA:3578] [KO:K05432]
   IL12 [HSA:3592 3593] [KO:K05406 K05425]
   IL13 [HSA:3596] [KO:K05435]
   IL22 [HSA:50616] [KO:K05445]
   IL23 [HSA:51561] [KO:K05426]
   IFNA [HSA:3439 3440 3441 3442 3443 3444 3445 3446 3447 3448 3449 3451 3452] [KO:K05414]
   IFNG [HSA:3458] [KO:K04687]
   NGF [HSA:4803] [KO:K02582]
   HGF [HSA:3082] [KO:K05460]
   LTA [HSA:4049] [KO:K05468]
   CCL2 [HSA:6347] [KO:K14624]
   protective antigen (PA) [KO:K11030]
   IgE [KO:K06856]
   GD2 [GL:G00114]
 
 Others

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Last updated: April 4, 2018

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