Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
       alpha1a-adrenergic receptor [HSA:148] [KO:K04135]
       alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
         Epinephrine [DG:DG00013]
         Adrenalone [DG:DG00016]
         Etilefrine [DG:DG00210]
         Norepinephrine [DG:DG00212]
         Norfenefrine [DG:DG00214]
         Phenylephrine [DG:DG00215]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Methoxamine [DG:DG00219]
         Midodrine [DG:DG00224]
         Arbutamine
         Ephedrine [DG:DG00227]
         Prazosin [DG:DG00253]
         Indoramin [DG:DG00254]
         Trimazosin [DG:DG00255]
         Doxazosin [DG:DG00256]
         Urapidil [DG:DG00257]
         Ketanserin [DG:DG00265]
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Nicergoline [DG:DG00283]
         Phenoxybenzamine [DG:DG00285]
         Moxisylyte [DG:DG00287]
         Ifenprodil [DG:DG00292]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
           D07905  Ergometrine (INN)
           D01163  Ergonovine maleate (USP)
Agonist/Antagonist
Agonist/Antagonist
         Alfuzosin [DG:DG00489]
         Tamsulosin [DG:DG00490]
         Terazosin [DG:DG00491]
         Silodosin
         Dihydroergotamine [DG:DG00833]
         Ergotamine [DG:DG00834]
         Levomepromazine [DG:DG00868]
         Sertindole
         Pimozide
         Clozapine
         Asenapine
         Olanzapine [DG:DG00898]
         Quetiapine [DG:DG00899]
         Risperidone
         Mianserin [DG:DG00951]
         Oxymetazoline [DG:DG01029]
         Tetryzoline [DG:DG01030]
         Xylometazoline [DG:DG01031]
         Naphazoline [DG:DG01032]
         Tramazoline [DG:DG01033]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Dapiprazole
         Amidephrine
         Amosulalol
         Arotinolol
         Bunazosin
         Bunitrolol
         Dipivefrin
         Guanadrel
         Medroxalol
         Methylephedrine
         Naftopidil
         Pelanserin
         Setiptiline
       alpha2b-adrenergic receptor [HSA:151] [KO:K04139]
       alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
         Epinephrine [DG:DG00013]
         Norepinephrine [DG:DG00212]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Ephedrine [DG:DG00227]
         Methyldopa (levorotatory) [DG:DG00248]
         Clonidine [DG:DG00249]
         Guanfacine [DG:DG00250]
         Rilmenidine
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Phenoxybenzamine [DG:DG00285]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
           D07905  Ergometrine (INN)
           D01163  Ergonovine maleate (USP)
Agonist/Antagonist
Agonist/Antagonist
         Yohimbin [DG:DG00485]
         Tizanidine [DG:DG00773]
         Piribedil
         Chlorpromazine [DG:DG00867]
         Levomepromazine [DG:DG00868]
         Asenapine
         Dexmedetomidine [DG:DG00926]
         Mianserin [DG:DG00951]
         Mirtazapine
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Apraclonidine [DG:DG01130]
         Brimonidine
         Dapiprazole
         Aptazapine
         Atipamezole
         Delequamine
         Detomidine
         Dipivefrin
         Fluparoxan
         Guanabenz
         Guanadrel
         Levonordefrin
         Methylephedrine
         Medetomidine
         Romifidine
         Setiptiline
         Xylazine; Veterinary
       beta1-adrenergic receptor [HSA:153] [KO:K04141]
       beta2-adrenergic receptor [HSA:154] [KO:K04142]
       beta3-adrenergic receptor [HSA:155] [KO:K04143]
     Dopamine
       dopamine D1-receptor [HSA:1812] [KO:K04144]
       dopamine D2-receptor [HSA:1813] [KO:K04145]
         Metoclopramide [DG:DG00055]
         Domperidone [DG:DG00057]
         Bromopride
         Alizapride [DG:DG00058]
         Clebopride [DG:DG00059]
         Metopimazine
         Dopamine [DG:DG00213]
         Dopexamine
         Ibopamine [DG:DG00223]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
           D07905  Ergometrine (INN)
           D01163  Ergonovine maleate (USP)
Agonist/Antagonist
Agonist/Antagonist
         Bromocriptine [DG:DG00452]
         Lisuride [DG:DG00453]
         Cabergoline
         Quinagolide [DG:DG00454]
         Terguride
         Apomorphine [DG:DG00486]
         Dihydroergotamine [DG:DG00833]
         Ergotamine [DG:DG00834]
         Levodopa
         Pergolide [DG:DG00861]
         Ropinirole [DG:DG00862]
         Pramipexole [DG:DG00863]
         Piribedil
         Rotigotine
         Chlorpromazine [DG:DG00867]
         Levomepromazine [DG:DG00868]
         Promazine
         Triflupromazine [DG:DG00871]
         Fluphenazine [DG:DG00874]
         Perphenazine [DG:DG00875]
         Prochlorperazine [DG:DG00876]
         Trifluoperazine [DG:DG00877]
         Thioproperazine [DG:DG00879]
         Periciazine
         Thioridazine [DG:DG00882]
         Haloperidol [DG:DG00885]
         Trifluperidol [DG:DG00886]
         Moperone [DG:DG00888]
         Pipamperone [DG:DG00889]
         Bromperidol [DG:DG00890]
         Droperidol
         Molindone [DG:DG00891]
         Sertindole
         Ziprasidone [DG:DG00892]
         Flupentixol [DG:DG00893]
         Clopenthixol
         Tiotixene [DG:DG00895]
         Zuclopenthixol [DG:DG00896]
         Pimozide
         Loxapine [DG:DG00897]
         Clozapine
         Olanzapine [DG:DG00898]
         Quetiapine [DG:DG00899]
         Asenapine
         Sulpiride
         Sultopride [DG:DG00900]
         Tiapride [DG:DG00901]
         Remoxipride [DG:DG00902]
         Levosulpiride
         Risperidone
         Mosapramine [DG:DG00905]
         Zotepine
         Aripiprazole
         Paliperidone [DG:DG00907]
         Opipramol [DG:DG00930]
         Aplindore
         Bifeprunox
         Blonanserin
         Brexpiprazole
         Butaclamol
         Cariprazine
         Carvotroline
         Ciladopa
         Clocapramine
         Gevotroline
         Iloperidone
         Lergotrile
         Lurasidone
         Mazapertine
         Methoxypromazine
         Nemonapride
         Oxiperomide
         Pardoprunox
         Perospirone
         Piquindone
         Pridopidine
         Quinelorane
         Quinpirole
         Spiperone
         Sibenadet
         Talipexole
         Timiperone
         Tiospirone
         Raclopride C11
       dopamine D3-receptor [HSA:1814] [KO:K04146]
       dopamine D4-receptor [HSA:1815] [KO:K04147]
       dopamine D5-receptor [HSA:1816] [KO:K05840]
     Histamine
     Serotonin
       5-HT1A-receptor [HSA:3350] [KO:K04153]
       5-HT1B-receptor [HSA:3351] [KO:K04153]
       5-HT1D-receptor [HSA:3352] [KO:K04153]
       5-HT1E-receptor [HSA:3354] [KO:K04153]
       5-HT1F-receptor [HSA:3355] [KO:K04153]
       5-HT1-receptor [HSA:3350 3351 3352 3354 3355] [KO:K04153]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
           D07905  Ergometrine (INN)
           D01163  Ergonovine maleate (USP)
Agonist/Antagonist
Agonist/Antagonist
         Metergoline
         Pizotifen [DG:DG00842]
         Asenapine
         Mianserin [DG:DG00951]
         Vilazodone [DG:DG00964]
         Indorenate
       5-HT2A-receptor [HSA:3356] [KO:K04157]
       5-HT2B-receptor [HSA:3357] [KO:K04157]
       5-HT2C-receptor [HSA:3358] [KO:K04157]
       5-HT2-receptor [HSA:3356 3357 3358] [KO:K04157]
       5-HT3-receptor [HSA:3359 9177 170572 200909 285242] [KO:K04819]
       5-HT4-receptor [HSA:3360] [KO:K04160]
       5-HT5-receptor [HSA:3361] [KO:K04161]
       5-HT6-receptor [HSA:3362] [KO:K04162]
       5-HT7-receptor [HSA:3363] [KO:K04163]
     Tachykinin / neurokinin
     Ghrelin
     Orexin
     Neuropeptide Y
     Opioid
     Angiotensin
     Bradykinin
     Endothelin
     Lutropin-choriogonadotropic hormone
     Follicle stimulating hormone
     Oxytocin
     Vasopressin
     Melanocortin
     Gonadotropin-releasing hormone
     Somatostatin
     Thyrotropin-releasing hormone
     Cholecystokinin
     Motilin
     Thrombin
     Purine / pyrimidine
     Adenosine
     Prostaglandin
     Prostacyclin
     Leukotriene
     Thromboxane
     Sphingolipid
     Free fatty acid
     Cannabinoid
     Platelet activating factor
     Melatonin
     Cysteinyl leukotriene
   Secretin receptor family
   Metabotropic glutamate receptor family
   Others
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
 
 Others

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Last updated: July 22, 2014

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