Target-based Classification of Drugs

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     Remark
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
       alpha1a-adrenergic receptor [HSA:148] [KO:K04135]
       alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
         Epinephrine [DG:DG00013]
         Adrenalone [DG:DG00016]
         Etilefrine [DG:DG00210]
         Norepinephrine [DG:DG00212]
         Norfenefrine [DG:DG00214]
         Phenylephrine [DG:DG00215]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Methoxamine [DG:DG00219]
         Midodrine [DG:DG00224]
         Arbutamine
         Ephedrine [DG:DG00227]
         Prazosin [DG:DG00253]
         Indoramin [DG:DG00254]
         Trimazosin [DG:DG00255]
         Doxazosin [DG:DG00256]
         Urapidil [DG:DG00257]
         Ketanserin [DG:DG00265]
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Nicergoline [DG:DG00283]
         Phenoxybenzamine [DG:DG00285]
         Moxisylyte [DG:DG00287]
         Ifenprodil [DG:DG00292]
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
         Alfuzosin [DG:DG00489]
         Tamsulosin [DG:DG00490]
         Terazosin [DG:DG00491]
         Silodosin
         Dihydroergotamine [DG:DG00833]
         Ergotamine [DG:DG00834]
         Levomepromazine [DG:DG00868]
         Sertindole
         Pimozide
         Clozapine
         Asenapine
         Olanzapine [DG:DG00898]
         Quetiapine [DG:DG00899]
         Risperidone
         Mianserin [DG:DG00951]
         Oxymetazoline [DG:DG01029]
         Tetryzoline [DG:DG01030]
         Xylometazoline [DG:DG01031]
         Naphazoline [DG:DG01032]
         Tramazoline [DG:DG01033]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Dapiprazole
         Amidephrine
         Amosulalol
         Arotinolol
         Bunazosin
         Bunitrolol
         Dipivefrin
         Guanadrel
         Medroxalol
         Methylephedrine
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP16)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Naftopidil
         Pelanserin
         Setiptiline
       alpha2b-adrenergic receptor [HSA:151] [KO:K04139]
       alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
         Epinephrine [DG:DG00013]
         Norepinephrine [DG:DG00212]
         Oxedrine [DG:DG00217]
         Metaraminol [DG:DG00218]
         Ephedrine [DG:DG00227]
         Methyldopa (levorotatory) [DG:DG00248]
         Clonidine [DG:DG00249]
         Guanfacine [DG:DG00250]
         Rilmenidine
         Phentolamine [DG:DG00280]
         Tolazoline [DG:DG00281]
         Phenoxybenzamine [DG:DG00285]
         Methylergometrine [DG:DG00445]
         Ergot alkaloids
         Ergometrine [DG:DG00446]
         Yohimbin [DG:DG00485]
         Tizanidine [DG:DG00773]
         Piribedil
         Chlorpromazine [DG:DG00867]
         Levomepromazine [DG:DG00868]
         Asenapine
         Dexmedetomidine [DG:DG00926]
         Mianserin [DG:DG00951]
         Mirtazapine
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Apraclonidine [DG:DG01130]
         Brimonidine
         Dapiprazole
         Aptazapine
         Atipamezole
         Delequamine
         Detomidine
         Dipivefrin
         Fluparoxan
         Guanabenz
         Guanadrel
         Levonordefrin
         Methylephedrine
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP16)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Medetomidine
         Romifidine
         Setiptiline
         Xylazine; Veterinary
       beta1-adrenergic receptor [HSA:153] [KO:K04141]
         Epinephrine [DG:DG00013]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Dobutamine [DG:DG00216]
         Prenalterol
         Arbutamine
         Ephedrine [DG:DG00227]
         Xamoterol [DG:DG00231]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Pindolol
         Propranolol [DG:DG00305]
         Sotalol [DG:DG00307]
         Timolol [DG:DG00306]
         Nadolol
         Mepindolol
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Cloranolol
         Practolol
         Metoprolol [DG:DG00313]
         Atenolol
         Acebutolol [DG:DG00314]
         Betaxolol [DG:DG00315]
         Bevantolol
         Bisoprolol [DG:DG00316]
         Celiprolol [DG:DG00317]
         Esmolol [DG:DG00318]
         Epanolol
         S-atenolol
         Nebivolol [DG:DG00319]
         Talinolol
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol
         Adaprolol
         Alprenoxime
         Amosulalol
         Arotinolol
         Bucindolol
         Bucumolol
         Bufetolol
         Bunitrolol
         Bunolol
         Butopamine
         Cetamolol
         Cicloprolol
         Cimaterol
         Denopamine
         Dexpropranolol
         Diacetolol
         Dipivefrin
         Flestolol
         Indenolol
         Landiolol
         Levdobutamine
         Levobetaxolol
         Methylephedrine
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP16)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Medroxalol
         Nipradilol
         Pamatolol
         Primidolol
         Talibegron
         Tilisolol
       beta2-adrenergic receptor [HSA:154] [KO:K04142]
         Epinephrine [DG:DG00013]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Dopexamine
         Arbutamine
         Ephedrine [DG:DG00227]
         Isoxsuprine [DG:DG00277]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Pindolol
         Propranolol [DG:DG00305]
         Timolol [DG:DG00306]
         Sotalol [DG:DG00307]
         Nadolol
         Mepindolol
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Cloranolol
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Ritodrine [DG:DG00450]
         Fenoterol [DG:DG00451]
         Pseudoephedrine [DG:DG01042]
         Orciprenaline [DG:DG01044]
         Salbutamol
         Terbutaline [DG:DG01046]
         Rimiterol
         Hexoprenaline [DG:DG01047]
         Isoetarine
         Pirbuterol [DG:DG01048]
         Tretoquinol [DG:DG01049]
         Carbuterol
         Tulobuterol [DG:DG01050]
         Salmeterol [DG:DG01051]
         Formoterol [DG:DG01052]
         Clenbuterol [DG:DG01053]
         Reproterol [DG:DG01054]
         Procaterol [DG:DG01055]
         Bitolterol [DG:DG01056]
         Indacaterol [DG:DG01057]
         Methoxyphenamine
         Dipivefrine
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol
         Bambuterol [DG:DG01060]
         Abediterol
         Adaprolol
         Amosulalol
         Albuterol
         Alprenoxime
         Arformoterol
         Arotinolol
         Bucindolol
         Bucumolol
         Bufetolol
         Bunitrolol
         Bunolol
         Butoxamine
         Carazolol
         Cetamolol
         Cicloprolol
         Cimaterol
         Clorprenaline
         Colterol
         Dexpropranolol
         Diacetolol
         Dipivefrin
         Flestolol
         Indenolol
         Methylephedrine
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP16)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Milveterol
         Isoetharine
         Levalbuterol
         Levosalbutamol
         Mabuterol
         Metaproterenol
         Medroxalol
         Nipradilol
         Olodaterol [DG:DG01058]
         Pamatolol
         Primidolol
         Picumeterol
         Ractopamine
         Sibenadet
         Soterenol
         Talibegron
         Tilisolol
         Vilanterol
         Zinterol
       beta3-adrenergic receptor [HSA:155] [KO:K04143]
         Epinephrine [DG:DG00013]
         Isoprenaline [DG:DG00211]
         Norepinephrine [DG:DG00212]
         Arbutamine
         Ephedrine [DG:DG00227]
         Buphenine [DG:DG00278]
         Alprenolol [DG:DG00303]
         Oxprenolol [DG:DG00304]
         Pindolol
         Propranolol [DG:DG00305]
         Timolol [DG:DG00306]
         Nadolol
         Mepindolol
         Carteolol [DG:DG00308]
         Tertatolol [DG:DG00309]
         Bopindolol [DG:DG00310]
         Bupranolol [DG:DG00311]
         Penbutolol [DG:DG00312]
         Cloranolol
         Labetalol [DG:DG00320]
         Carvedilol [DG:DG00321]
         Pseudoephedrine [DG:DG01042]
         Dipivefrine
         Levobunolol [DG:DG01136]
         Metipranolol [DG:DG01137]
         Befunolol
         Adaprolol
         Alprenoxime
         Amibegron
         Amosulalol
         Arotinolol
         Bucindolol
         Bufetolol
         Bunitrolol
         Bunolol
         Cetamolol
         Cicloprolol
         Cimaterol
         Dexpropranolol
         Diacetolol
         Dipivefrin
         Fasobegron
         Flestolol
         Medroxalol
         Methylephedrine
           D08206  Methylephedrine (BAN)
           D01952  L-Methylephedrine hydrochloride (JAN)
           D02109  dl-Methylephedrine hydrochloride (JP16)
           D09842  dl-Methylephedrine saccharinate (JAN)
Agonist
Agonist
Agonist
Agonist
         Mirabegron
         Nipradilol
         Primidolol
         Pamatolol
         Ritobegron
         Solabegron
         Talibegron
         Tilisolol
     Dopamine
     Histamine
     Serotonin
     Tachykinin / neurokinin
     Ghrelin
     Orexin
     Neuropeptide Y
     Opioid
     Angiotensin
     Bradykinin
     Endothelin
     Lutropin-choriogonadotropic hormone
     Follicle stimulating hormone
     Oxytocin
     Vasopressin
     Melanocortin
     Gonadotropin-releasing hormone
     Somatostatin
     Thyrotropin-releasing hormone
     Cholecystokinin
     Motilin
     Thrombin
     Purine / pyrimidine
     Adenosine
     Prostaglandin
     Prostacyclin
     Leukotriene
     Thromboxane
     Sphingolipid
     Free fatty acid
     Cannabinoid
     Platelet activating factor
     Melatonin
     Cysteinyl leukotriene
   Secretin receptor family
   Metabotropic glutamate receptor family
   Others
 
 Cytokine receptors
 
 Nuclear receptors
 
 Ion channels
 
 Transporters
 
 Enzymes
 
 Protein kinases
 
 Cytokines
 
 Others

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Last updated: July 22, 2014

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