Risk Category of Japanese OTC Drugs

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1st Level  2nd Level  3rd Level  4th Level  5th Level 

 Drugs requiring guidance
 
 First-class OTC drugs
 
 Designated second-class OTC drugs
 
 Second-class OTC drugs
   Inorganic and organic chemicals
     Acrinol hydrate
     Acitazanolast
     Aspirin
     Acetaminophen
     Azelastine
     Adenosinetriphosphoric acid
       D08646  Triphosadenine (DCF)
       D02300  Adenosine triphosphate disodium hydrate (JAN)
       D08647  Triphosadenine disodium salt
     Adrenaline (Epinephrine)
     Ethyl aminobenzoate
     Amorolfine
     Alimemazine
     Allylisopropylacetylurea
     Aldioxa
     Alloclamide
     Benzoic acid
     Ambroxol
     Isothipendyl
     Isopropamide
     Isopropylantipyrine
     Ibuprofen
     Ibuprofen piconol
     Iproheptine
     Indometacin
     Ufenamate
     Exalamide
     Econazole
     Estradiol
     Estradiol benzoate
     Ethanol
     Ethinylestradiol
     Ethyl cysteine
     Ethenzamide
     Epinastine
     Ephedrine
     Emedastine
     Ergocalciferol or Cholecalciferol
     Oxyquinoline
     Oxiconazole
     Oxytetracycline
     Oxyphencyclimine
     Oxypolyethoxydodecane
     Oxymetazoline
     Oxethazaine
     Kainic acid
     Casanthranol
     Ferric oxide, saccharated
     Carbinoxamine
     Carbocysteine
     Reduced iron
     Guaiacol
     Potassium guaiacolsulfonate
     Ferric ammonium citrate
     Griseofulvin
     Glycerin
     Creosote
     Cresol
     Cresolsulphonate
     Clemastine
     Clotrimazole
     Cloperastine
     Cromoglicic acid
     Chloramphenicol
     Chlorzoxazone
     Chlorphenamine
     Chlorhexidine
     Aluminum silicate
     Magnesium aluminosilicate
     Ketotifen
     Ketoprofen
     Codeine
     Colistin
     Cortisone acetate
     Sasapyrine
     Sanalmin; Aluminum magnesium hydroxide
     Salicylamide
     Salicylated alum powder
     Salicylic acid
     Phenyl salicylate
     Lead oxide
     Santonin
     Sodium hypochlorite
     Diethyldithiocarbamate
     Dioctyl sodium sulfosuccinate
     Dental phenol with camphor
     Ciclopirox olamine
     Diclofenac
     Dichloroisocyanuric acid
     Dicycloverine
     Bismuth subsalicylate
     Bismuth subnitrate
     Bismuth subcarbonate
     Siccanin
     Dihydroxialuminium
     Dihydrocodeine
     Difeterol
     Diphenidol
     Diphenylpiperidinomethyldioxolan iodide
     Diphenylpyraline
     Diphenhydramine
     Dibucaine
     Dibunate
     Diprophylline
     Bismuth subgallate
     Dimenhydrinate
     Sodium bromide
     Cerium oxalate
     Magnesia alumina hydrate; Sanalmin
     Aluminum hydroxide
     Aluminum hydroxide - calcium carbonate - magnesium carbonate coprecipitate
     Aluminum hydroxide - sodium bicarbonate coprecipitate
     Aluminum hydroxide - magnesium carbonate
     Potassium hydroxide
     Aluminum hydroxide - aluminum potassium sulfate coprecipitate
     Sucralfate
     Scopolamine
     Sucralfate hydrate - macrogol mixture
     Sulconazole
     Sulfadiazine
     Sulfamine
     Sulfamethoxazole
     Sulfisoxazole
     Sulfisomidine
     Cetrimide
     Sennoside
     Sofalcone
     Lead carbonate
     Albumin tannate
     Tioconazole
     Tiquizium
     Tipepidine
     Timepidium bromide
     DEET; N,N-Diethyl-meta-toluamide
     Theobromine
     Dexamethasone
     Dexamethasone acetate
     Dextromethorphan
     Thesit
     Thesit - Desitin
     Tetracycline
     Tetryzoline
     Teprenone
     Demethylchlortetracycline
     Terbinafine
     Triamcinolone acetonide
     Trichloroisocyanuric acid
     Trichomycin
     Triprolidine
     Tripelennamine
     Trimethylcetylammonium pentachlorophenate
     Trimetoquinol
     Trimebutine
     Tolciclate
     Tolnaftate
     Troxipide
     Thonzylamine
     Nystatin
     Naphazoline
     Nicotine
     Nitrophenol
     Ferrous lactate
     Neticonazole
     Bacitracin
     Papaverine
     Haloprogin
     Picosulfate
     Bisacodyl
     Vitamin A oil
     Aluminum hydroxynaphthoate
     Hydrocortisone
     Hydrocortisone acetate
     Hydrocortisone butyrate
     Hydrotalcite
     Bifonazole
     Piperazine
     Ethyl piperidinoacetylaminobenzoate
     Pyrvinium pamoate
     Pirenzepine
     Pyrrolnitrin
     Piroxicam
     Piroctone olamine
     Ferric pyrophosphate
     Phytonadione
     Phylloquinone
     Fexofenadine
     Pheniramine
     Phenylephrine
     Fenethazine
     Phenol
     Phenol and zinc oxide liniment
     Phenothrin
     Felbinac
     Pseudoephedrine
     Scopolamine butylbromide
     Butenafine
     Bufexamac
     Ferrous fumarate
     Fradiomycin
     Pranoprofen
     Flavoxate
     Fluocinolone acetonide
     Prednisolone
     Prednisolone acetate
     Prednisolone valerate
     Procaine
     Proxyphylline
     Bromhexine
     Bromovalerylurea
     Promethazine
     Hexamine
     Beclometasone dipropionate
     Bethanechol chloride
     Betamethasone valerate
     Heparin sodium
     Heparinoid
     Pemirolast potassium
     Veradoline
     Belladonna extract
     Periphermine
     Berberine
     Pentoxyverine
     Pentoxy pentane
     Homosulfamine
     Polyethylenesulfonate
     Polymyxin B
     Mercurochrome
     Miconazole
     Mequitazine
     Meclizine hydrochloride
     Sodium aluminometasilicate
     Magnesium aluminometasilicate
     Metixene
     Methylatropine
     Anisotropine methylbromide
     Methylephedrine
     Methyloctatropine
     Methyl L-cysteine
     Methylscopolamine
     Hyoscyamine methylbromide
     Methylbenactyzium
     Methocarbamol
     Methoxyphenamine
     Methdilazine
     Mepivacaine
     Mebhydrolin
     Meprylcaine hydrochloride
     Mononitroguaiacol
     Rauwolfia serpentina
     Lactylphenetidine
     Lanoconazole
     Lidocaine
     Lithospermum root
     Cobalt sulfate
     Ferrous sulfate
     Cupric sulfate
     Manganese sulfate
     Resorcin
     Vitamin A
     Retinol acetate
     Retinol palmitate
     Scopolia extract
     Scopolia rhizome
     Loperamide
   Crude drugs
   TCM formulas
   Not used for human
 
 Third-class OTC drugs
OTC drugs that contain as active ingredients the substances listed above including their hydrates and salts
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Last updated: June 14, 2017
English translation by the Kanehisa Laboratories

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