KEGG Orthology (KO) - Chelonia mydas (green sea turtle)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
     00010 Glycolysis / Gluconeogenesis [PATH:cmy00010]
     00020 Citrate cycle (TCA cycle) [PATH:cmy00020]
     00030 Pentose phosphate pathway [PATH:cmy00030]
     00040 Pentose and glucuronate interconversions [PATH:cmy00040]
     00051 Fructose and mannose metabolism [PATH:cmy00051]
     00052 Galactose metabolism [PATH:cmy00052]
     00053 Ascorbate and aldarate metabolism [PATH:cmy00053]
     00500 Starch and sucrose metabolism [PATH:cmy00500]
       102948110 SI; sucrase-isomaltase (alpha-glucosidase)
       102939927 GAA; glucosidase, alpha; acid
       102946527 GANC; glucosidase, alpha; neutral C
       102932811 probable beta-D-xylosidase 7-like
       102947298 GBA3; glucosidase, beta, acid 3
       102941725 TREH; trehalase (brush-border membrane glycoprotein)
       102938999 UGDH; UDP-glucose 6-dehydrogenase
       102944299 UGT1A1; UDP glucuronosyltransferase 1 family, polypeptide A1
       102936292 UDP-glucuronosyltransferase 2A1-like
       102946236 UDP-glucuronosyltransferase 1-6-like
       102946467 UDP-glucuronosyltransferase 1-1-like
       102946014 UDP-glucuronosyltransferase 1-1-like
       102932111 GUSB; glucuronidase, beta
       102944632 KL; klotho
       102947194 UXS1; UDP-glucuronate decarboxylase 1
       102935605 UGP2; UDP-glucose pyrophosphorylase 2
       102943564 PGM1; phosphoglucomutase 1
       102940381 PGM2; phosphoglucomutase 2
       102933769 HKDC1; hexokinase domain containing 1
       102934001 HK1; hexokinase 1
       102930728 hexokinase-2-like
       102932759 GCK; glucokinase (hexokinase 4)
       102933338 G6PC3; glucose 6 phosphatase, catalytic, 3
       102935880 glucose-6-phosphatase-like
       102945158 glucose-6-phosphatase-like
       102935291 G6PC2; glucose-6-phosphatase, catalytic, 2
       102936106 glucose-6-phosphatase-like
       102947183 PGM2L1; phosphoglucomutase 2-like 1
       102944823 GPI; glucose-6-phosphate isomerase
       102943491 1
       102945524 PYGM; phosphorylase, glycogen, muscle
       102933324 PYGB; phosphorylase, glycogen; brain
       102948377 PYGL; phosphorylase, glycogen, liver
       102944417 GYS2; glycogen synthase 2 (liver)
       102943466 GYS1; glycogen synthase 1 (muscle)
       102933401 pancreatic alpha-amylase-like
       102947904 AGL; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
       102942975 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1
       102940608 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3
K12047 MGAM; maltase-glucoamylase [EC:3.2.1.20 3.2.1.3]
K12316 GAA; lysosomal alpha-glucosidase [EC:3.2.1.20]
K12317 GANC; neutral alpha-glucosidase C [EC:3.2.1.20]
K05349 bglX; beta-glucosidase [EC:3.2.1.21]
K05350 bglB; beta-glucosidase [EC:3.2.1.21]
K01194 TREH; alpha,alpha-trehalase [EC:3.2.1.28]
K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
K14756 KL; klotho [EC:3.2.1.31]
K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35]
K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K11809 PGM2L1; glucose-1,6-bisphosphate synthase [EC:2.7.1.106]
K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
K00700 glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K01176 E3.2.1.1; alpha-amylase [EC:3.2.1.1]
K01196 AGL; glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
     00520 Amino sugar and nucleotide sugar metabolism [PATH:cmy00520]
     00620 Pyruvate metabolism [PATH:cmy00620]
     00630 Glyoxylate and dicarboxylate metabolism [PATH:cmy00630]
     00640 Propanoate metabolism [PATH:cmy00640]
     00650 Butanoate metabolism [PATH:cmy00650]
     00660 C5-Branched dibasic acid metabolism
     00562 Inositol phosphate metabolism [PATH:cmy00562]
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion
     04910 Insulin signaling pathway [PATH:cmy04910]
       102935680 INS; insulin
       102935205 INSR; insulin receptor
       102945843 IRS1; insulin receptor substrate 1
       102934421 IRS2; insulin receptor substrate 2
       102931359 PIK3R5; phosphoinositide-3-kinase, regulatory subunit 5
       102941819 PIK3R3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
       102933845 PIK3R2; phosphoinositide-3-kinase, regulatory subunit 2 (beta)
       102945631 PIK3R1; phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
       102945282 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
       102936956 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
       102932183 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
       102929971 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
       102946336 PDPK1; 3-phosphoinositide dependent protein kinase-1
       102947630 AKT2; v-akt murine thymoma viral oncogene homolog 2
       102929975 AKT3; v-akt murine thymoma viral oncogene homolog 3
       102939884 AKT1; v-akt murine thymoma viral oncogene homolog 1
       102935600 GSK3B; glycogen synthase kinase 3 beta
       102944417 GYS2; glycogen synthase 2 (liver)
       102943466 GYS1; glycogen synthase 1 (muscle)
       102929648 PPP1CB; protein phosphatase 1, catalytic subunit, beta isozyme
       102937166 serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like
       102931057 serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like
       102937635 PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme
       102942920 uncharacterized LOC102942920
       102944607 PPP1R3C; protein phosphatase 1, regulatory subunit 3C
       102940247 PPP1R3B; protein phosphatase 1, regulatory subunit 3B
       102937720 PPP1R3D; protein phosphatase 1, regulatory subunit 3D
       102947792 PPP1R3A; protein phosphatase 1, regulatory subunit 3A
       102933198 protein phosphatase 1 regulatory subunit 3C-B-like
       102939493 PHKG1; phosphorylase kinase, gamma 1 (muscle)
       102934958 PHKG2; phosphorylase kinase, gamma 2 (testis)
       102948122 PHKB; phosphorylase kinase, beta
       102943595 PHKA2; phosphorylase kinase, alpha 2 (liver)
       102947074 PHKA1; phosphorylase kinase, alpha 1 (muscle)
       102933404 calmodulin
       102937453 calglandulin-like
       102930460 Calmodulin; calmodulin-like
       102932045 CALM1; calmodulin 1 (phosphorylase kinase, delta)
       102947195 CALM2; calmodulin 2 (phosphorylase kinase, delta)
       102933632 calmodulin
       102945524 PYGM; phosphorylase, glycogen, muscle
       102933324 PYGB; phosphorylase, glycogen; brain
       102948377 PYGL; phosphorylase, glycogen, liver
       102938238 PDE3B; phosphodiesterase 3B, cGMP-inhibited
       102943305 PRKACB; protein kinase, cAMP-dependent, catalytic, beta
       102946871 PRKAR2B; protein kinase, cAMP-dependent, regulatory, type II, beta
       102939555 PRKAR1A; protein kinase, cAMP-dependent, regulatory, type I, alpha
       102936513 PRKAR1B; protein kinase, cAMP-dependent, regulatory, type I, beta
       102941653 cAMP-dependent protein kinase type II-alpha regulatory subunit-like
       102936764 PRKCZ; protein kinase C, zeta
       102942221 PRKCI; protein kinase C, iota
       102935953 SLC2A4; solute carrier family 2 (facilitated glucose transporter), member 4
       102940218 FLOT2; flotillin 2
       102929737 FLOT1; flotillin 1
       102947329 SH2B adapter protein 2-like
       102941012 sorbin and SH3 domain-containing protein 1-like
       102937369 CBL; Cbl proto-oncogene, E3 ubiquitin protein ligase
       102943844 CBLB; Cbl proto-oncogene B, E3 ubiquitin protein ligase
       102942619 crk-like protein-like
       102944956 CRK; v-crk avian sarcoma virus CT10 oncogene homolog
       102941951 RAPGEF1; Rap guanine nucleotide exchange factor (GEF) 1
       102935679 RHOQ; ras homolog family member Q
       102941232 EXOC7; exocyst complex component 7
       102940781 TRIP10; thyroid hormone receptor interactor 10
       102946183 SREBF1; sterol regulatory element binding transcription factor 1
       102944285 acetyl-CoA carboxylase-like
       102932426 acetyl-CoA carboxylase-like
       102942822 ACACB; acetyl-CoA carboxylase beta
       102933656 FASN; fatty acid synthase
       102942996 PKLR; pyruvate kinase, liver and RBC
       102933769 HKDC1; hexokinase domain containing 1
       102934001 HK1; hexokinase 1
       102930728 hexokinase-2-like
       102932759 GCK; glucokinase (hexokinase 4)
       102940952 PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit
       102944011 PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit
       102931879 PRKAB1; protein kinase, AMP-activated, beta 1 non-catalytic subunit
       102938628 5'-AMP-activated protein kinase subunit beta-2-like
       102929680 PRKAG2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit
       102936816 PRKAG3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit
       102943724 PRKAG1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
       102939461 FOXO1; forkhead box O1
       102945488 PPARGC1A; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
       102933338 G6PC3; glucose 6 phosphatase, catalytic, 3
       102935880 glucose-6-phosphatase-like
       102945158 glucose-6-phosphatase-like
       102935291 G6PC2; glucose-6-phosphatase, catalytic, 2
       102936106 glucose-6-phosphatase-like
       102934321 FBP2; fructose-1,6-bisphosphatase 2
       102936795 FBP1; fructose-1,6-bisphosphatase 1
       102934020 PCK1; phosphoenolpyruvate carboxykinase 1 (soluble)
       102943510 PCK2; phosphoenolpyruvate carboxykinase 2 (mitochondrial)
       102947284 serine/threonine-protein kinase mTOR-like
       102935793 serine/threonine-protein kinase mTOR-like
       102940371 RPTOR; regulatory associated protein of MTOR, complex 1
       102948337 RPS6KB1; ribosomal protein S6 kinase, 70kDa, polypeptide 1
       102932417 RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2
       102938544 RPS6; ribosomal protein S6
       102946334 EIF4E; eukaryotic translation initiation factor 4E
       102939093 eukaryotic translation initiation factor 4E type 2-like
       102939516 TSC1; tuberous sclerosis 1
       102946461 TSC2; tuberous sclerosis 2
       102932877 RHEB; Ras homolog enriched in brain
       102931799 BAD; BCL2-associated agonist of cell death
       102941809 SHC1; SHC (Src homology 2 domain containing) transforming protein 1
       102933759 SHC2; SHC (Src homology 2 domain containing) transforming protein 2
       102938973 SHC3; SHC (Src homology 2 domain containing) transforming protein 3
       102934651 SHC4; SHC (Src homology 2 domain containing) family, member 4
       102945306 GRB2; growth factor receptor-bound protein 2
       102942399 SOS1; son of sevenless homolog 1 (Drosophila)
       102929489 SOS2; son of sevenless homolog 2 (Drosophila)
       102946454 HRAS; Harvey rat sarcoma viral oncogene homolog
       102941364 KRAS; Kirsten rat sarcoma viral oncogene homolog
       102943017 GTPase KRas-like
       102933328 NRAS; neuroblastoma RAS viral (v-ras) oncogene homolog
       102938595 BRAF; v-raf murine sarcoma viral oncogene homolog B
       102929883 RAF1; v-raf-1 murine leukemia viral oncogene homolog 1
       102945547 MAP2K1; mitogen-activated protein kinase kinase 1
       102931357 MAP2K2; mitogen-activated protein kinase kinase 2
       102942218 MAPK1; mitogen-activated protein kinase 1
       102932555 MAPK3; mitogen-activated protein kinase 3
       102941663 MKNK2; MAP kinase interacting serine/threonine kinase 2
       102934703 MKNK1; MAP kinase interacting serine/threonine kinase 1
       102932360 SOCS1; suppressor of cytokine signaling 1
       102945521 SOCS2; suppressor of cytokine signaling 2
       102945560 cytokine-inducible SH2-containing protein-like
       102930798 SOCS3; suppressor of cytokine signaling 3
       102931468 SOCS4; suppressor of cytokine signaling 4
       102946999 PTPN1; protein tyrosine phosphatase, non-receptor type 1
       102937047 PTPRF; protein tyrosine phosphatase, receptor type, F
       102934812 MAPK9; mitogen-activated protein kinase 9
       102932835 MAPK10; mitogen-activated protein kinase 10
       102935187 MAPK8; mitogen-activated protein kinase 8
       102932073 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
       102929354 INPPL1; inositol polyphosphate phosphatase-like 1
       102929300 phosphatidylinositol 3
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07193 APS; SH2B adapter protein 2
K06086 SORBS1; sorbin and SH3 domain containing 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K04438 CRK; proto-oncogene C-crk
K04438 CRK; proto-oncogene C-crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K07194 RHOQ; Ras homolog gene family, member Q
K07195 EXOC7; exocyst complex component 7
K07196 TRIP10; thyroid hormone receptor interactor 10
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; Bcl-2-antagonist of cell death
K06279 SHC1; SHC- transforming protein 1
K17447 SHC2; SHC- transforming protein 2
K17448 SHC3; SHC- transforming protein 3
K17449 SHC4; SHC- transforming protein 4
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
     04922 Glucagon signaling pathway
     04923 Regulation of lipolysis in adipocyte
     04920 Adipocytokine signaling pathway [PATH:cmy04920]
     03320 PPAR signaling pathway [PATH:cmy03320]
     04912 GnRH signaling pathway [PATH:cmy04912]
     04913 Ovarian Steroidogenesis
     04915 Estrogen signaling pathway
     04914 Progesterone-mediated oocyte maturation [PATH:cmy04914]
     04917 Prolactin signaling pathway
     04921 Oxytocin signaling pathway
     04918 Thyroid hormone synthesis
     04919 Thyroid hormone signaling pathway
     04916 Melanogenesis [PATH:cmy04916]
     04924 Renin secretion
     04614 Renin-angiotensin system
     04925 Aldosterone synthesis and secretion
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Aging
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
     04930 Type II diabetes mellitus
     04940 Type I diabetes mellitus
     04950 Maturity onset diabetes of the young
     04932 Non-alcoholic fatty liver disease (NAFLD)
     04931 Insulin resistance [PATH:cmy04931]
       102935680 INS; insulin
       102930971 RPS6KA2; ribosomal protein S6 kinase, 90kDa, polypeptide 2
       102934881 RPS6KA3; ribosomal protein S6 kinase, 90kDa, polypeptide 3
       102934696 RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6
       102942323 ribosomal protein S6 kinase 2 alpha-like
       102929648 PPP1CB; protein phosphatase 1, catalytic subunit, beta isozyme
       102937166 serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like
       102931057 serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like
       102937635 PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme
       102942920 uncharacterized LOC102942920
       102944607 PPP1R3C; protein phosphatase 1, regulatory subunit 3C
       102940247 PPP1R3B; protein phosphatase 1, regulatory subunit 3B
       102937720 PPP1R3D; protein phosphatase 1, regulatory subunit 3D
       102947792 PPP1R3A; protein phosphatase 1, regulatory subunit 3A
       102933198 protein phosphatase 1 regulatory subunit 3C-B-like
       102935205 INSR; insulin receptor
       102945843 IRS1; insulin receptor substrate 1
       102946999 PTPN1; protein tyrosine phosphatase, non-receptor type 1
       102934329 PTPN11; protein tyrosine phosphatase, non-receptor type 11
       102934807 tyrosine-protein phosphatase non-receptor type 11-like
       102937047 PTPRF; protein tyrosine phosphatase, receptor type, F
       102945282 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
       102936956 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
       102932183 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
       102929971 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
       102931359 PIK3R5; phosphoinositide-3-kinase, regulatory subunit 5
       102941819 PIK3R3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
       102933845 PIK3R2; phosphoinositide-3-kinase, regulatory subunit 2 (beta)
       102945631 PIK3R1; phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
       102947284 serine/threonine-protein kinase mTOR-like
       102935793 serine/threonine-protein kinase mTOR-like
       102948337 RPS6KB1; ribosomal protein S6 kinase, 70kDa, polypeptide 1
       102932417 RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2
       102942074 PRKCB; protein kinase C, beta
       102935916 IL6; interleukin 6 (interferon, beta 2)
       102932633 STAT3; signal transducer and activator of transcription 3 (acute-phase response factor)
       102930798 SOCS3; suppressor of cytokine signaling 3
       102935600 GSK3B; glycogen synthase kinase 3 beta
       102944417 GYS2; glycogen synthase 2 (liver)
       102943466 GYS1; glycogen synthase 1 (muscle)
       102936332 tumor necrosis factor-like
       102942749 tumor necrosis factor receptor superfamily member 1A-like
       102934812 MAPK9; mitogen-activated protein kinase 9
       102932835 MAPK10; mitogen-activated protein kinase 10
       102935187 MAPK8; mitogen-activated protein kinase 8
       102932073 IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
       102937973 NFKBIA; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
       102944582 NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
       102947354 RELA; v-rel avian reticuloendotheliosis viral oncogene homolog A
       102942806 nitric oxide synthase
       102936764 PRKCZ; protein kinase C, zeta
       102930228 TBC1 domain family member 4-like
       102935953 SLC2A4; solute carrier family 2 (facilitated glucose transporter), member 4
       102940952 PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit
       102944011 PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit
       102931879 PRKAB1; protein kinase, AMP-activated, beta 1 non-catalytic subunit
       102938628 5'-AMP-activated protein kinase subunit beta-2-like
       102929680 PRKAG2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit
       102936816 PRKAG3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit
       102943724 PRKAG1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
       102942822 ACACB; acetyl-CoA carboxylase beta
       102941741 CPT1B; carnitine palmitoyltransferase 1B (muscle)
       102944091 SLC27A1; solute carrier family 27 (fatty acid transporter), member 1
       102944373 SLC27A4; solute carrier family 27 (fatty acid transporter), member 4
       102929566 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2
       102945748 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3
       102939714 SLC27A6; solute carrier family 27 (fatty acid transporter), member 6
       102930209 CD36; CD36 molecule (thrombospondin receptor)
       102938526 PRKCQ; protein kinase C, theta
       102945932 PRKCD; protein kinase C, delta
       102947309 PPP2R4; protein phosphatase 2A activator, regulatory subunit 4
       102946183 SREBF1; sterol regulatory element binding transcription factor 1
       102934421 IRS2; insulin receptor substrate 2
       102943644 TRIB3; tribbles pseudokinase 3
       102945524 PYGM; phosphorylase, glycogen, muscle
       102933324 PYGB; phosphorylase, glycogen; brain
       102948377 PYGL; phosphorylase, glycogen, liver
       102939461 FOXO1; forkhead box O1
       102934020 PCK1; phosphoenolpyruvate carboxykinase 1 (soluble)
       102943510 PCK2; phosphoenolpyruvate carboxykinase 2 (mitochondrial)
       102933338 G6PC3; glucose 6 phosphatase, catalytic, 3
       102935880 glucose-6-phosphatase-like
       102945158 glucose-6-phosphatase-like
       102935291 G6PC2; glucose-6-phosphatase, catalytic, 2
       102936106 glucose-6-phosphatase-like
       102940285 SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2
       102941155 NR1H3; nuclear receptor subfamily 1, group H, member 3
       102933178 PPARGC1B; peroxisome proliferator-activated receptor gamma, coactivator 1 beta
       102932055 MLXIP; MLX interacting protein
       102942947 MLX; MLX, MAX dimerization protein
       102935037 MLXIPL; MLX interacting protein-like
       102948296 MLX-interacting protein-like
       102943921 CPT1A; carnitine palmitoyltransferase 1A (liver)
       102936130 PRKCE; protein kinase C, epsilon
       102945488 PPARGC1A; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
       102943186 PPARA; peroxisome proliferator-activated receptor alpha
       102946336 PDPK1; 3-phosphoinositide dependent protein kinase-1
       102947630 AKT2; v-akt murine thymoma viral oncogene homolog 2
       102929975 AKT3; v-akt murine thymoma viral oncogene homolog 3
       102939884 AKT1; v-akt murine thymoma viral oncogene homolog 1
       102941367 PTEN; phosphatase and tensin homolog
       102948301 MGEA5; meningioma expressed antigen 5 (hyaluronidase)
       102932353 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit-like
       102938516 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit-like
       102938870 solute carrier family 2
       102935199 GFPT2; glutamine-fructose-6-phosphate transaminase 2
       102944455 GFPT1; glutamine--fructose-6-phosphate transaminase 1
       102939459 CRTC2; CREB regulated transcription coactivator 2
       102944794 CREB1; cAMP responsive element binding protein 1
       102946430 CREB3L4; cAMP responsive element binding protein 3-like 4
       102948242 CREB3; cAMP responsive element binding protein 3
       102939907 CREB3L2; cAMP responsive element binding protein 3-like 2
       102940413 CREB3L1; cAMP responsive element binding protein 3-like 1
       102941831 CREB3L3; cAMP responsive element binding protein 3-like 3
       102933695 CREB5; cAMP responsive element binding protein 5
K04526 INS; insulin
K04373 RPS6KA; p90 ribosomal S6 kinase [EC:2.7.11.1]
K04373 RPS6KA; p90 ribosomal S6 kinase [EC:2.7.11.1]
K04373 RPS6KA; p90 ribosomal S6 kinase [EC:2.7.11.1]
K04373 RPS6KA; p90 ribosomal S6 kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K05405 IL6; interleukin 6
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3; suppressor of cytokine signaling 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K17902 TBC1D4; TBC1 domain family member 4
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
K08749 SLC27A6; solute carrier family 27 (fatty acid transporter), member 6
K06259 CD36; CD36 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4; serine/threonine-protein phosphatase 2A activator
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K07187 IRS2; insulin receptor substrate 2
K19518 TRIB3; tribbles homolog 3
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K00688 E2.4.1.1; starch phosphorylase [EC:2.4.1.1]
K07201 FOXO1; forkhead box protein O1
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K08536 NR1H3; liver X receptor alpha
K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K15719 NCOAT; protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]
K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K00820 glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
K00820 glmS; glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
     04933 AGE-RAGE signaling pathway in diabetic complications [PATH:cmy04933]
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: May 24, 2016