KEGG Orthology (KO) - Danio rerio (zebrafish)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:dre00061]
     00062 Fatty acid elongation [PATH:dre00062]
     00071 Fatty acid degradation [PATH:dre00071]
     00072 Synthesis and degradation of ketone bodies [PATH:dre00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:dre00100]
     00120 Primary bile acid biosynthesis [PATH:dre00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:dre00140]
     00561 Glycerolipid metabolism [PATH:dre00561]
     00564 Glycerophospholipid metabolism [PATH:dre00564]
     00565 Ether lipid metabolism [PATH:dre00565]
     00600 Sphingolipid metabolism [PATH:dre00600]
     00590 Arachidonic acid metabolism [PATH:dre00590]
       402802 pla2g12a; group XIIA secretory phospholipase A2 precursor
       571738 pla2g1b; phospholipase A2 precursor
       436622 zgc:92162; group 10 secretory phospholipase A2
       406739 pla2g12b; group XIIB secretory phospholipase A2-like protein precursor
       641423 zgc:123275; group 3 secretory phospholipase A2 precursor
       100149324 proca1; uncharacterized protein proca1
       30554 pla2g4aa; cytosolic phospholipase A2
       565386 pla2g4f.2; cytosolic phospholipase A2 zeta-like
       100148818 si:ch73-55i23.1; cytosolic phospholipase A2 gamma-like
       798864 pla2g4f.1; cytosolic phospholipase A2 zeta-like
       559087 pla2g4ab; cytosolic phospholipase A2
       406370 pla2g6; 85/88 kDa calcium-independent phospholipase A2
       560649 si:ch211-214p16.3; phospholipase B1, membrane-associated
       436896 zgc:92249; retinoic acid receptor responder protein 3
       246226 ptgs1; prostaglandin G/H synthase 1 precursor
       559020 ptgs2b; prostaglandin G/H synthase 2 precursor
       246227 ptgs2a; prostaglandin-endoperoxide synthase 2 precursor
       544666 ptges; prostaglandin E synthase
       799964 ptgesl; prostaglandin E synthase 2
       406449 ptges3a; prostaglandin E synthase 3
       415227 ptges3b; prostaglandin E synthase 3
       373866 cbr1; carbonyl reductase [NADPH] 1
       337696 cbr1l; carbonyl reductase [NADPH] 1
       406605 fam213b; prostamide/prostaglandin F synthase
       792041 tbxas1; thromboxane-A synthase
       336492 ptgdsb.1; prostaglandin D2 synthase, brain precursor
       751701 ptgdsb.2; lipocalin-15 precursor
       559148 ptgis; prostacyclin synthase
       567204 alox5a; arachidonate 5-lipoxygenase
       406575 lta4h; leukotriene A-4 hydrolase
       100037390 cyp4f3; leukotriene-B(4) omega-hydroxylase 2
       100535432 ltc4s; leukotriene C4 synthase
       566746 ggt1l2.2; gamma-glutamyltranspeptidase 1 isoform X1
       100333757 ggt5b; gamma-glutamyltransferase 5
       569014 ggt1b; gamma-glutamyltranspeptidase 1-like
       393387 ggt1a; gamma-glutamyltranspeptidase 1
       569734 ggt5a; gamma-glutamyltransferase 5
       352926 gpx1a; glutathione peroxidase 1
       552981 gpx7; glutathione peroxidase 7 precursor
       798788 gpx3; glutathione peroxidase 3 precursor
       393191 gpx8; probable glutathione peroxidase 8
       100334384 gpx2; glutathione peroxidase 2
       100034406 cyp2p7; cytochrome P450, family 2, subfamily P, polypeptide 7
       393592 cyp2p9; cytochrome P450, family 2, subfamily P, polypeptide 9
       399485 cyp2p10; cytochrome P450, family 2, subfamily P, polypeptide 10
       797309 cyp2j20; cytochrome P450 2J5
       393108 cyp2p6; cytochrome P450, family 2, subfamily P, polypeptide 6
       100034366 cyp2p8; cytochrome P450, family 2, subfamily P, polypeptide 8
       556280 cyp2u1; cytochrome P450 2U1
       322732 alox12; arachidonate 15-lipoxygenase
       494099 ephx2; bifunctional epoxide hydrolase 2
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K15729 PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
K05309 PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15717 K15717; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
K01832 TBXAS1; thromboxane-A synthase [EC:5.3.99.5]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
K17726 CYP4F2_3; leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]
K00807 LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07422 CYP2U1; cytochrome P450 family 2 subfamily U polypeptide 1
K00458 ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
     00591 Linoleic acid metabolism [PATH:dre00591]
     00592 alpha-Linolenic acid metabolism [PATH:dre00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:dre01040]
     01004 Lipid biosynthesis proteins [BR:dre01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system
     02022 Two-component system
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04010 MAPK signaling pathway [PATH:dre04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:dre04012]
     04310 Wnt signaling pathway [PATH:dre04310]
     04330 Notch signaling pathway [PATH:dre04330]
     04340 Hedgehog signaling pathway [PATH:dre04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:dre04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway -fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:dre04370]
       30682 vegfaa; vascular endothelial growth factor A-A isoform 1 precursor
       558154 vegfab; vascular endothelial growth factor A isoform 1 precursor
       554230 kdr; vascular endothelial growth factor receptor 2 precursor
       373867 plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
       561747 plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       497384 prkca; protein kinase C alpha type
       100333967 si:ch73-374l24.1; protein kinase C alpha type isoform X1
       100006675 prkcba; protein kinase C, beta a
       393953 prkcbb; protein kinase C beta type
       100003514 prkcg; protein kinase C alpha type-like
       100331840 sphk1; sphingosine kinase 1
       100150090 sphk2; sphingosine kinase 2 isoform X1
       553656 hrasb; -Ha-ras Harvey rat sarcoma viral oncogene homolog b
       550286 hrasa; GTPase HRas
       445289 kras; GTPase KRas
       393228 zgc:55558; uncharacterized protein LOC393228
       103909873 ras-like protein isoform X1
       30380 nras; GTPase NRas precursor
       30716 raf1a; RAF proto-oncogene serine/threonine-protein kinase
       557109 raf1b; RAF proto-oncogene serine/threonine-protein kinase
       406728 map2k1; dual specificity mitogen-activated protein kinase kinase 1
       563181 map2k2a; dual specificity mitogen-activated protein kinase kinase 2
       100002225 map2k2b; dual specificity mitogen-activated protein kinase kinase 2
       360144 mapk1; mitogen-activated protein kinase 1
       399480 mapk3; mitogen-activated protein kinase 3
       30554 pla2g4aa; cytosolic phospholipase A2
       565386 pla2g4f.2; cytosolic phospholipase A2 zeta-like
       100148818 si:ch73-55i23.1; cytosolic phospholipase A2 gamma-like
       798864 pla2g4f.1; cytosolic phospholipase A2 zeta-like
       559087 pla2g4ab; cytosolic phospholipase A2
       794574 ppp3ca; protein phosphatase 3, catalytic subunit, alpha isozyme
       557926 ppp3cca; protein phosphatase 3, catalytic subunit, gamma isoform-like
       550554 ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit alpha
       565241 ppp3ccb; protein phosphatase 3, catalytic subunit, gamma isoform
       447814 ppp3r1b; protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b
       564337 ppp3r1a; calcineurin subunit B type 1
       100333254 nfatc2a; nuclear factor of activated T-cells, cytoplasmic 2
       559020 ptgs2b; prostaglandin G/H synthase 2 precursor
       246227 ptgs2a; prostaglandin-endoperoxide synthase 2 precursor
       142986 ptk2ab; focal adhesion kinase 1
       386705 ptk2aa; protein tyrosine kinase 2aa
       562011 shc2; SHC-transforming protein 2
       399546 pxna; paxillin a
       565130 pxnb; paxillin-like isoform X3
       336839 cdc42; cell division control protein 42 homolog isoform 2
       556226 cdc42l2; cell division cycle 42 like 2
       793158 cdc42l; cell division control protein 42 homolog
       65237 mapk14a; mitogen-activated protein kinase 14A
       266756 mapk14b; mitogen-activated protein kinase 14B
       30681 mapk12a; mitogen-activated protein kinase 12
       415185 mapk11; mitogen-activated protein kinase 11
       557810 mapk12b; mitogen-activated protein kinase 12
       562552 zgc:171775; uncharacterized protein LOC562552
       100002318 mapk13; mitogen-activated protein kinase 13
       327321 mapkapk2a; MAP kinase-activated protein kinase 2
       790934 mapkapk3; MAP kinase-activated protein kinase 3
       368243 hspb1; heat shock protein beta-1
       325084 src; proto-oncogene tyrosine-protein kinase Src
       394174 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       561737 pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100002263 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       404211 pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta
       100000252 pik3r3b; phosphatidylinositol 3-kinase regulatory subunit gamma
       557176 pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha
       327204 rac1a; ras-related C3 botulinum toxin substrate 1
       792699 rac1l; ras-related C3 botulinum toxin substrate 1
       562838 rac1b; uncharacterized protein LOC562838
       415151 rac2; ras-related C3 botulinum toxin substrate 2
       437027 rac3a; ras-related C3 botulinum toxin substrate 3
       795167 rac3b; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
       403146 akt2l; RAC-alpha serine/threonine-protein kinase
       560549 akt3a; RAC-gamma serine/threonine-protein kinase
       378972 akt2; RAC-beta serine/threonine-protein kinase
       100149794 akt3b; RAC-gamma serine/threonine-protein kinase
       101910198 akt1; RAC-alpha serine/threonine-protein kinase
       492763 casp9; caspase 9, apoptosis-related cysteine protease
       58100 badb; BCL2-antagonist of cell death b isoform 1
K05448 VEGFA; vascular endothelial growth factor A
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase Kras
K07827 KRAS; GTPase Kras
K07827 KRAS; GTPase Kras
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC-transforming protein 2
K05760 PXN; paxillin
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
     04371 Apelin signaling pathway [PATH:dre04371]
     04630 Jak-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:dre04068]
     04020 Calcium signaling pathway [PATH:dre04020]
     04070 Phosphatidylinositol signaling system [PATH:dre04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP - PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:dre04150]
     04075 Plant hormone signal transduction
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases

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Last updated: April 24, 2017