| |
KO |
 Metabolism
|
|
|
Carbohydrate metabolism
|
 00010 Glycolysis / Gluconeogenesis [PATH:ecb00010]
|
00020 Citrate cycle (TCA cycle) [PATH:ecb00020]
|
00030 Pentose phosphate pathway [PATH:ecb00030]
|
00040 Pentose and glucuronate interconversions [PATH:ecb00040]
|
00051 Fructose and mannose metabolism [PATH:ecb00051]
|
00052 Galactose metabolism [PATH:ecb00052]
|
00053 Ascorbate and aldarate metabolism [PATH:ecb00053]
|
00500 Starch and sucrose metabolism [PATH:ecb00500]
|
 100064486 MGAM; maltase-glucoamylase, intestinal isoform X2
100065270 MGAM2; putative maltase-glucoamylase-like protein FLJ16351
100056675 GAA; lysosomal alpha-glucosidase
100070973 GANC; neutral alpha-glucosidase C isoform X2
100063242 SI; sucrase-isomaltase, intestinal
100051543 UGP2; UTP--glucose-1-phosphate uridylyltransferase isoform X3
100073097 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1
100067583 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase family member 3
100073089 ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X3
100067990 cytosolic beta-glucosidase
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100058811 GYG1; glycogenin-1
100064536 GYG2; glycogenin-2 isoform X1
100034152 GBE1; 1,4-alpha-glucan-branching enzyme
100057085 PYGB; glycogen phosphorylase, brain form isoform X1
100066726 PYGL; glycogen phosphorylase, liver form
100050345 PYGM; glycogen phosphorylase, muscle form
100050695 AGL; glycogen debranching enzyme
100049851 pancreatic alpha-amylase
100051073 pancreatic alpha-amylase
100071276 TREH; trehalase
100069980 PGM1; phosphoglucomutase-1 isoform X1
100064893 PGM2; phosphoglucomutase-2
100068725 HK3; hexokinase-3 isoform X1
100009677 HK2; hexokinase-2
100072687 HK1; hexokinase-1 isoform X2
100072686 HKDC1; putative hexokinase HKDC1
100051836 glucokinase
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100052026 PGM2L1; glucose 1,6-bisphosphate synthase isoform X1
100057160 GPI; glucose-6-phosphate isomerase
|
K12047 MGAM; maltase-glucoamylase [EC:3.2.1.20 3.2.1.3]
K12047 MGAM; maltase-glucoamylase [EC:3.2.1.20 3.2.1.3]
K12316 GAA; lysosomal alpha-glucosidase [EC:3.2.1.20]
K12317 GANC; neutral alpha-glucosidase C [EC:3.2.1.20]
K01203 SI; sucrase-isomaltase [EC:3.2.1.48 3.2.1.10]
K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K05350 bglB; beta-glucosidase [EC:3.2.1.21]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00750 GYG1; glycogenin [EC:2.4.1.186]
K00750 GYG1; glycogenin [EC:2.4.1.186]
K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K01196 AGL; glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33]
K01176 AMY; alpha-amylase [EC:3.2.1.1]
K01176 AMY; alpha-amylase [EC:3.2.1.1]
K01194 TREH; alpha,alpha-trehalase [EC:3.2.1.28]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K11809 PGM2L1; glucose-1,6-bisphosphate synthase [EC:2.7.1.106]
K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
|
00520 Amino sugar and nucleotide sugar metabolism [PATH:ecb00520]
|
00620 Pyruvate metabolism [PATH:ecb00620]
|
00630 Glyoxylate and dicarboxylate metabolism [PATH:ecb00630]
|
00640 Propanoate metabolism [PATH:ecb00640]
|
00650 Butanoate metabolism [PATH:ecb00650]
|
00660 C5-Branched dibasic acid metabolism
|
00562 Inositol phosphate metabolism [PATH:ecb00562]
|
|
|
Energy metabolism
|
|
|
Lipid metabolism
|
|
|
Nucleotide metabolism
|
|
|
Amino acid metabolism
|
|
|
Metabolism of other amino acids
|
|
|
Glycan biosynthesis and metabolism
|
|
|
Metabolism of cofactors and vitamins
|
|
|
Metabolism of terpenoids and polyketides
|
|
|
Biosynthesis of other secondary metabolites
|
|
|
Xenobiotics biodegradation and metabolism
|
|
|
Enzyme families
|
|
|
Genetic Information Processing
|
|
|
Environmental Information Processing
|
|
|
Membrane transport
|
|
|
Signal transduction
|
02020 Two-component system
|
02022 Two-component system
|
04014 Ras signaling pathway [PATH:ecb04014]
|
04015 Rap1 signaling pathway [PATH:ecb04015]
|
04010 MAPK signaling pathway [PATH:ecb04010]
|
04013 MAPK signaling pathway - fly
|
04016 MAPK signaling pathway - plant
|
04011 MAPK signaling pathway - yeast
|
04012 ErbB signaling pathway [PATH:ecb04012]
|
04310 Wnt signaling pathway [PATH:ecb04310]
|
04330 Notch signaling pathway [PATH:ecb04330]
|
04340 Hedgehog signaling pathway [PATH:ecb04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:ecb04350]
|
04390 Hippo signaling pathway [PATH:ecb04390]
|
04391 Hippo signaling pathway -fly
|
04392 Hippo signaling pathway - multiple species [PATH:ecb04392]
|
04370 VEGF signaling pathway [PATH:ecb04370]
|
04371 Apelin signaling pathway [PATH:ecb04371]
|
04630 Jak-STAT signaling pathway [PATH:ecb04630]
|
04064 NF-kappa B signaling pathway [PATH:ecb04064]
|
04668 TNF signaling pathway [PATH:ecb04668]
|
04066 HIF-1 signaling pathway [PATH:ecb04066]
|
04068 FoxO signaling pathway [PATH:ecb04068]
|
04020 Calcium signaling pathway [PATH:ecb04020]
|
04070 Phosphatidylinositol signaling system [PATH:ecb04070]
|
04072 Phospholipase D signaling pathway [PATH:ecb04072]
|
04071 Sphingolipid signaling pathway [PATH:ecb04071]
|
04024 cAMP signaling pathway [PATH:ecb04024]
|
04022 cGMP - PKG signaling pathway [PATH:ecb04022]
|
04151 PI3K-Akt signaling pathway [PATH:ecb04151]
|
106782874 EGF; pro-epidermal growth factor isoform X1
100060423 TGFA; protransforming growth factor alpha isoform X1
100056605 EREG; proepiregulin
100050528 AREG; amphiregulin
100033960 FGF1; fibroblast growth factor 1
100033955 FGF2; fibroblast growth factor 2
100033961 FGF7; fibroblast growth factor 7
100056444 FGF17; fibroblast growth factor 17 isoform X3
100071790 FGF16; fibroblast growth factor 16
100050353 FGF9; fibroblast growth factor 9
100060219 FGF5; fibroblast growth factor 5 isoform X1
100052655 FGF10; fibroblast growth factor 10
100050037 FGF20; fibroblast growth factor 20
100060309 FGF8; fibroblast growth factor 8
100051221 FGF6; fibroblast growth factor 6
100629648 FGF18; fibroblast growth factor 18
100072461 FGF22; fibroblast growth factor 22
100146649 FGF3; fibroblast growth factor 3
100060525 FGF4; fibroblast growth factor 4
100060488 FGF19; fibroblast growth factor 19
100054542 FGF21; fibroblast growth factor 21
100058460 FGF23; fibroblast growth factor 23
100065669 NGF; beta-nerve growth factor
100009689 BDNF; brain-derived neurotrophic factor precursor
100051839 NTF3; neurotrophin-3 isoform X2
100054859 NTF4; neurotrophin-4
111776000 INS; insulin
100034198 IGF1; insulin-like growth factor I precursor
100034182 IGF2; insulin-like growth factor II precursor
100055086 PDGFA; platelet-derived growth factor subunit A isoform X1
100070283 PDGFB; platelet-derived growth factor subunit B isoform X1
100062015 PDGFC; platelet-derived growth factor C isoform X2
100061488 PDGFD; platelet-derived growth factor D isoform X1
100146493 CSF1; macrophage colony-stimulating factor 1 isoform X1
100034127 KITLG; kit ligand precursor
100055522 FLT3LG; fms-related tyrosine kinase 3 ligand isoform X1
100033839 VEGFA; vascular endothelial growth factor A precursor
100055238 VEGFB; vascular endothelial growth factor B isoform X1
100051349 PGF; placenta growth factor isoform X1
100050877 VEGFD; vascular endothelial growth factor D isoform X1
100060890 VEGFC; vascular endothelial growth factor C isoform X1
100049848 HGF; hepatocyte growth factor isoform X1
100056482 ANGPT1; angiopoietin-1 isoform X1
100051890 ANGPT2; angiopoietin-2 isoform X2
100067818 ANGPT4; angiopoietin-4 isoform X1
100063240 EFNA4; ephrin-A4 isoform X1
100073202 EFNA5; ephrin-A5 isoform X1
100063307 EFNA1; ephrin-A1
100057186 EFNA3; ephrin-A3 isoform X1
111774429 EFNA2; ephrin-A2
100067755 EGFR; epidermal growth factor receptor isoform X1
100054739 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100059216 ERBB3; receptor tyrosine-protein kinase erbB-3
100050182 ERBB4; receptor tyrosine-protein kinase erbB-4 isoform X6
100057614 FGFR1; fibroblast growth factor receptor 1 isoform X1
100033956 FGFR2; fibroblast growth factor receptor 2 precursor
100034114 FGFR3; fibroblast growth factor receptor 3 isoform X1
100068679 FGFR4; fibroblast growth factor receptor 4 isoform X2
100069694 NGFR; tumor necrosis factor receptor superfamily member 16
100064594 NTRK1; high affinity nerve growth factor receptor
100061700 NTRK2; BDNF/NT-3 growth factors receptor isoform X3
100066248 INSR; insulin receptor isoform X1
100055698 IGF1R; insulin-like growth factor 1 receptor
100059815 PDGFRA; platelet-derived growth factor receptor alpha
100071665 PDGFRB; platelet-derived growth factor receptor beta isoform X2
100060422 CSF1R; macrophage colony-stimulating factor 1 receptor precursor
100009704 KIT; mast/stem cell growth factor receptor Kit precursor
100061780 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
100033957 FLT1; vascular endothelial growth factor receptor 1 precursor
100066773 FLT4; vascular endothelial growth factor receptor 3 isoform X1
100033959 KDR; vascular endothelial growth factor receptor 2 isoform X2
100056013 MET; hepatocyte growth factor receptor precursor
100066963 TEK; angiopoietin-1 receptor
100053644 EPHA2; ephrin type-A receptor 2 isoform X3
100051866 GRB2; growth factor receptor-bound protein 2
100053889 SOS1; son of sevenless homolog 1 isoform X1
100066282 SOS2; son of sevenless homolog 2 isoform X1
100055481 HRAS; GTPase HRas isoform X1
100064473 KRAS; GTPase KRas isoform X1
100051785 LOW QUALITY PROTEIN: GTPase KRas-like
100059469 NRAS; GTPase NRas
100051110 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100065996 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
100063190 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100066173 MAPK3; mitogen-activated protein kinase 3
100057701 MAPK1; mitogen-activated protein kinase 1 isoform X2
100061987 IRS1; insulin receptor substrate 1
100009701 TLR2; toll-like receptor 2 precursor
100066890 TLR4; toll-like receptor 4 precursor
100061732 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
100146643 immunoglobulin epsilon heavy chain
100063383 SYK; tyrosine-protein kinase SYK isoform X3
100147468 CD19; B-lymphocyte antigen CD19 precursor
100070796 PIK3AP1; phosphoinositide 3-kinase adapter protein 1 isoform X1
100034180 GH1; somatotropin precursor
100034034 PRL; prolactin precursor
100064031 OSM; oncostatin-M
100034204 IL2; interleukin-2 precursor
100034196 IL6; interleukin-6 precursor
100034225 IL4; interleukin-4 precursor
100059131 IL7; interleukin-7 isoform X3
100064468 interferon alpha-2-like
100064551 interferon alpha-2-like
100052921 interferon alpha-4 precursor
100052818 IFN-ALPHA2; interferon alpha-2 precursor
100629951 interferon alpha-1
100053110 interferon alpha-4
100053022 IFNA1; interferon alpha-1 precursor
100053210 interferon alpha-2-like
100064612 interferon alpha-2-like
100064731 IFND1; interferon delta 1 precursor
100064975 IFND2; interferon-delta 2 precursor
100629885 interferon alpha-2-like
100052545 IFNB1; interferon beta precursor
100052658 interferon beta-like
100147174 interferon beta
100033849 EPO; erythropoietin precursor
100033922 CSF3; granulocyte colony-stimulating factor isoform 2
100053020 GHR; growth hormone receptor isoform X2
100053793 PRLR; prolactin receptor
100066819 OSMR; oncostatin-M-specific receptor subunit beta isoform X4
100070292 IL2RA; interleukin-2 receptor subunit alpha precursor
100069676 IL2RB; interleukin-2 receptor subunit beta isoform X2
100055911 IL2RG; cytokine receptor common subunit gamma
102148787 IL6R; interleukin-6 receptor subunit alpha isoform X2
791252 IL4R; interleukin-4 receptor subunit alpha precursor
100034169 IL7R; interleukin-7 receptor subunit alpha precursor
100063402 IFNAR1; interferon alpha/beta receptor 1
100052489 IFNAR2; interferon alpha/beta receptor 2 isoform X1
100057022 EPOR; erythropoietin receptor isoform X1
100069253 CSF3R; granulocyte colony-stimulating factor receptor isoform X5
100054008 JAK1; tyrosine-protein kinase JAK1 isoform X1
100051487 JAK2; tyrosine-protein kinase JAK2 isoform X1
100147451 JAK3; tyrosine-protein kinase JAK3 isoform X1
100033877 COL1A1; collagen alpha-1(I) chain
100051715 COL1A2; collagen alpha-2(I) chain
791241 COL2A1; collagen alpha-1(II) chain precursor
100062160 COL4A4; collagen alpha-4(IV) chain isoform X1
100066148 COL4A1; collagen alpha-1(IV) chain
100060112 COL4A6; collagen alpha-6(IV) chain isoform X1
100054545 COL4A5; collagen alpha-5(IV) chain isoform X5
100066264 COL4A2; collagen alpha-2(IV) chain
100037402 COL4A3; collagen alpha-3(IV) chain
100055332 COL6A2; collagen alpha-2(VI) chain isoform X1
100066356 COL6A3; collagen alpha-3(VI) chain isoform X3
100050035 COL6A1; collagen alpha-1(VI) chain
100064285 COL6A6; collagen alpha-6(VI) chain isoform X1
100064145 collagen alpha-4(VI) chain-like
100064173 COL6A5; collagen alpha-5(VI) chain isoform X1
100058660 COL9A3; collagen alpha-3(IX) chain
100057208 COL9A1; collagen alpha-1(IX) chain isoform X1
100009713 COL9A2; collagen alpha-2(IX) chain
100059860 LAMA1; laminin subunit alpha-1 isoform X1
100073067 LAMA2; laminin subunit alpha-2 isoform X3
791238 LAMA3; laminin subunit alpha-3 isoform X1
100058057 LAMA5; laminin subunit alpha-5
100066875 LAMA4; laminin subunit alpha-4 isoform X2
100060360 LAMB1; laminin subunit beta-1
100053539 LAMB2; laminin subunit beta-2 isoform X1
100056564 LAMB3; laminin subunit beta-3
100060434 LAMB4; laminin subunit beta-4 isoform X1
100055269 LAMC1; laminin subunit gamma-1
791245 LAMC2; laminin subunit gamma-2 precursor
100069663 LAMC3; laminin subunit gamma-3
100147607 CHAD; chondroadherin
100058621 RELN; reelin isoform X1
100057478 THBS1; thrombospondin-1 precursor
100063449 THBS3; thrombospondin-3 isoform X1
100073261 THBS4; thrombospondin-4
100050044 THBS2; thrombospondin-2 precursor
100033911 COMP; cartilage oligomeric matrix protein precursor
100034189 FN1; fibronectin isoform X1
100053029 SPP1; osteopontin
100059034 VTN; vitronectin
100061556 TNN; tenascin-N isoform X3
100061691 TNR; tenascin-R isoform X1
100049835 TNC; tenascin isoform X1
100059315 TNXB; tenascin-X isoform X7
100059472 VWF; von Willebrand factor precursor
100052979 IBSP; bone sialoprotein 2
100063434 ITGA1; integrin alpha-1 precursor
100063367 ITGA2; integrin alpha-2
100009697 ITGA2B; integrin alpha-IIb precursor
100056202 ITGA3; integrin alpha-3 isoform X1
100067886 ITGA4; integrin alpha-4 isoform X1
100064655 ITGA5; integrin alpha-5
100064056 ITGA6; integrin alpha-6 isoform X1
100058756 ITGA7; integrin alpha-7 isoform X1
100056217 ITGA8; integrin alpha-8
100054374 ITGA9; integrin alpha-9 isoform X1
100065205 ITGA10; integrin alpha-10 isoform X4
100065211 ITGA11; integrin alpha-11 isoform X1
100068706 ITGAV; integrin alpha-V isoform X1
100055024 ITGB1; integrin beta-1 precursor
100009709 ITGB3; integrin beta-3 precursor
100051679 ITGB4; integrin beta-4 isoform X1
100070376 ITGB5; integrin beta-5
100051266 ITGB6; integrin beta-6 isoform X2
100063747 ITGB7; integrin beta-7 isoform X2
100053462 ITGB8; integrin beta-8
100058245 PTK2; focal adhesion kinase 1 isoform X12
100051623 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100058141 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
100051753 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100052122 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100050227 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
100146348 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100073278 F2R; proteinase-activated receptor 1 isoform X2
100064117 CHRM1; muscarinic acetylcholine receptor M1
100064906 CHRM2; muscarinic acetylcholine receptor M2
100053797 LPAR1; lysophosphatidic acid receptor 1
100052775 LPAR3; lysophosphatidic acid receptor 3
100071749 LPAR4; lysophosphatidic acid receptor 4
100147585 LPAR5; lysophosphatidic acid receptor 5
100629781 LPAR6; lysophosphatidic acid receptor 6
100061395 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
100067486 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
100052560 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X2
100058274 GNB4; guanine nucleotide-binding protein subunit beta-4
100146498 GNB5; guanine nucleotide-binding protein subunit beta-5
100630067 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
100063795 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
100058605 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
100064813 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
100059736 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
106782014 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
100630493 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
100051499 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
100063518 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
100630574 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
100065327 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
100051430 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
100069660 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X2
100050532 PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1
100062810 PIK3R5; phosphoinositide 3-kinase regulatory subunit 5 isoform X3
100062779 PIK3R6; phosphoinositide 3-kinase regulatory subunit 6 isoform X1
100630736 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
100055913 STK11; serine/threonine-protein kinase STK11 isoform X3
100034159 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
100009710 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
100072811 DDIT4; DNA damage-inducible transcript 4 protein
100066615 TSC1; hamartin isoform X1
100065679 TSC2; tuberin isoform X2
100064440 RHEB; GTP-binding protein Rheb
100146703 MLST8; target of rapamycin complex subunit LST8 isoform X1
100051341 MTOR; serine/threonine-protein kinase mTOR isoform X3
100056244 RPTOR; regulatory-associated protein of mTOR isoform X10
100057875 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
100057254 EIF4E2; eukaryotic translation initiation factor 4E type 2
100066216 EIF4E; eukaryotic translation initiation factor 4E isoform X1
100068758 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X2
100053005 RPS6KB2; ribosomal protein S6 kinase beta-2
100057481 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
100061920 EIF4B; eukaryotic translation initiation factor 4B isoform X3
100052368 RPS6; 40S ribosomal protein S6
100063318 PRKCA; protein kinase C alpha type isoform X1
100052266 PKN2; serine/threonine-protein kinase N2
100066882 PKN3; serine/threonine-protein kinase N3 isoform X1
102148973 PKN1; serine/threonine-protein kinase N1 isoform X1
100073151 SGK1; serine/threonine-protein kinase Sgk1 isoform X2
100070683 serine/threonine-protein kinase Sgk2 isoform X5
100052030 serine/threonine-protein kinase Sgk3 isoform X1
100064671 AKT2; RAC-beta serine/threonine-protein kinase
100054961 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100061130 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100062388 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100055681 THEM4; acyl-coenzyme A thioesterase THEM4
100062224 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
100062627 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
100070408 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
100070133 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1
100060957 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X5
100059955 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X2
100051737 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
100060079 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1
100053302 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X3
100057766 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1
100051948 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1
100054880 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
100054977 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X6
100054440 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
100050735 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X1
100034150 HSP90AB1; heat shock protein HSP 90-beta
100033837 HSP90AA1; heat shock protein HSP 90-alpha
100033933 HSP90B1; endoplasmin precursor
100055173 CDC37; hsp90 co-chaperone Cdc37
100056571 CRTC2; CREB-regulated transcription coactivator 2 isoform X1
100057142 PHLPP1; PH domain leucine-rich repeat-containing protein phosphatase 1
100054529 PHLPP2; PH domain leucine-rich repeat-containing protein phosphatase 2 isoform X1
100630002 TCL1A; T-cell leukemia/lymphoma protein 1A
100062315 MTCP1; protein p13 MTCP-1
100063339 NOS3; nitric oxide synthase, endothelial
100051990 BRCA1; breast cancer type 1 susceptibility protein isoform X4
100061033 GSK3B; glycogen synthase kinase-3 beta isoform X6
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100055710 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
100054903 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100068097 MYC; myc proto-oncogene protein
102149114 CCND1; G1/S-specific cyclin-D1
100064022 CDKN1A; cyclin-dependent kinase inhibitor 1
111773925 CDKN1B; cyclin-dependent kinase inhibitor 1B
100051790 CDK2; cyclin-dependent kinase 2 isoform X2
100051005 CDK4; cyclin-dependent kinase 4 isoform X2
100061625 CDK6; cyclin-dependent kinase 6 isoform X1
100051150 CCND2; G1/S-specific cyclin-D2
100066590 CCND3; G1/S-specific cyclin-D3 isoform X3
100055302 CCNE2; G1/S-specific cyclin-E2 isoform X1
100053882 CCNE1; G1/S-specific cyclin-E1
100066558 FOXO3; forkhead box protein O3
100060431 RBL2; retinoblastoma-like protein 2 isoform X2
100052326 FASLG; tumor necrosis factor ligand superfamily member 6
100064312 BCL2L11; bcl-2-like protein 11 isoform X6
100056060 YWHAZ; 14-3-3 protein zeta/delta
100056084 YWHAB; 14-3-3 protein beta/alpha
100057123 YWHAQ; 14-3-3 protein theta
100059962 YWHAE; 14-3-3 protein epsilon isoform X1
100062878 YWHAH; 14-3-3 protein eta
100059731 YWHAG; 14-3-3 protein gamma
100055447 BAD; bcl2-associated agonist of cell death
100053597 BCL2L1; bcl-2-like protein 1 isoform X1
100050934 BCL2; apoptosis regulator Bcl-2 isoform X1
100054331 CASP9; caspase-9
100066388 CREB1; cyclic AMP-responsive element-binding protein 1
100053304 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1
100070334 ATF4; cyclic AMP-dependent transcription factor ATF-4
100062307 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1
100064828 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
100057002 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1
100067794 CREB3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3
100063153 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
100054803 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1
100059348 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta isoform X1
100054765 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1
100069096 RXRA; retinoic acid receptor RXR-alpha isoform X1
100061353 NR4A1; nuclear receptor subfamily 4 group A member 1
100058432 IKBKG; NF-kappa-B essential modulator
100070393 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100050167 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100057483 RELA; transcription factor p65
100067894 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X4
100073162 MYB; transcriptional activator Myb isoform X1
100052084 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
100062044 TP53; cellular tumor antigen p53
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; nerve growth factor receptor (TNFR superfamily member 16)
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05415 IFNB; interferon beta
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K05055 IL6R; interleukin 6 receptor
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen, type I, alpha
K06236 COL1A; collagen, type I, alpha
K19719 COL2A; collagen, type II, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K06238 COL6A; collagen, type VI, alpha
K06238 COL6A; collagen, type VI, alpha
K06238 COL6A; collagen, type VI, alpha
K06238 COL6A; collagen, type VI, alpha
K06238 COL6A; collagen, type VI, alpha
K08131 COL9A; collagen, type IX, alpha
K08131 COL9A; collagen, type IX, alpha
K08131 COL9A; collagen, type IX, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1; lysophosphatidic acid receptor 1
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8; target of rapamycin complex subunit LST8
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN; protein kinase N [EC:2.7.11.13]
K06071 PKN; protein kinase N [EC:2.7.11.13]
K06071 PKN; protein kinase N [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA; retinoid X receptor alpha
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
|
04152 AMPK signaling pathway [PATH:ecb04152]
|
100065841 MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X2
100055913 STK11; serine/threonine-protein kinase STK11 isoform X3
100063745 CAB39; calcium-binding protein 39
100050219 CAB39L; calcium-binding protein 39-like
100064638 STRADA; STE20-related kinase adapter protein alpha isoform X1
100066574 STRADB; STE20-related kinase adapter protein beta isoform X1
100034042 LEP; leptin precursor
100069504 LEPR; leptin receptor isoform X1
100058510 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 isoform X1
100054461 ADRA1A; alpha-1A adrenergic receptor isoform X1
100059500 ADIPOQ; adiponectin
100052436 ADIPOR1; adiponectin receptor protein 1
100050051 ADIPOR2; adiponectin receptor protein 2
100034159 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
100009710 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
100034094 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
100034095 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
100034098 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2
100034096 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
100034099 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3
100062514 PFKFB1; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X3
100051146 PFKFB2; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform X1
100070251 PFKFB3; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X5
100053840 PFKFB4; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4 isoform X2
100063910 FBP1; fructose-1,6-bisphosphatase 1
100061491 FBP2; fructose-1,6-bisphosphatase isozyme 2
100070818 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1
100056927 PFKL; ATP-dependent 6-phosphofructokinase, liver type
100034116 PFKM; ATP-dependent 6-phosphofructokinase, muscle type
100056007 HNF4A; hepatocyte nuclear factor 4-alpha isoform X2
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100055710 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
100054903 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2
100056571 CRTC2; CREB-regulated transcription coactivator 2 isoform X1
100066388 CREB1; cyclic AMP-responsive element-binding protein 1
100062307 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1
100064828 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
100057002 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1
100067794 CREB3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3
100063153 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
100054803 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1
100055716 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X3
100060819 ELAVL1; ELAV-like protein 1
102149114 CCND1; G1/S-specific cyclin-D1
100072219 CCNA2; cyclin-A2
100147188 CCNA1; cyclin-A1
100058387 EEF2K; eukaryotic elongation factor 2 kinase isoform X2
100061437 EEF2; elongation factor 2
100050481 FOXO1; forkhead box protein O1
100066558 FOXO3; forkhead box protein O3
100072571 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X2
100033939 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100069598 LIPE; hormone-sensitive lipase isoform X1
100065577 HMGCR; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1
100052283 SREBF1; sterol regulatory element-binding protein 1 isoform X1
100057311 FASN; fatty acid synthase isoform X4
100071472 ACACA; acetyl-CoA carboxylase 1 isoform X1
100060968 SCD5; stearoyl-CoA desaturase 5
100060485 SCD; acyl-CoA desaturase
100066740 ACACB; acetyl-CoA carboxylase 2 isoform X1
100070049 MLYCD; malonyl-CoA decarboxylase, mitochondrial
100009716 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
100055438 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1
100056027 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform isoform X1
100062224 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
100062627 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
100070408 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
100070133 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1
100060957 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X5
100059955 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X2
100051737 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
100060079 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1
100053302 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X3
100057766 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1
100051948 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1
100054880 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
100054977 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X6
100054440 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
100050735 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X1
100055336 TBC1D1; TBC1 domain family member 1 isoform X1
100066413 RAB2A; ras-related protein Rab-2A
100147248 RAB8A; ras-related protein Rab-8A isoform X2
100055747 RAB10; ras-related protein Rab-10 isoform X1
100146180 RAB11B; ras-related protein Rab-11B
100067611 RAB14; ras-related protein Rab-14
100071259 CFTR; cystic fibrosis transmembrane conductance regulator
100049847 CD36; platelet glycoprotein 4 isoform X1
100034198 IGF1; insulin-like growth factor I precursor
100055698 IGF1R; insulin-like growth factor 1 receptor
111776000 INS; insulin
100066248 INSR; insulin receptor isoform X1
100061987 IRS1; insulin receptor substrate 1
100146249 IRS2; insulin receptor substrate 2 isoform X1
100069009 insulin receptor substrate 1 isoform X1
100059954 IRS4; insulin receptor substrate 4
100051623 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100058141 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
100051753 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100052122 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100050227 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
100146348 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100630736 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
100064671 AKT2; RAC-beta serine/threonine-protein kinase
100054961 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100061130 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100065679 TSC2; tuberin isoform X2
100066615 TSC1; hamartin isoform X1
100064440 RHEB; GTP-binding protein Rheb
100051341 MTOR; serine/threonine-protein kinase mTOR isoform X3
100056244 RPTOR; regulatory-associated protein of mTOR isoform X10
100052282 AKT1S1; proline-rich AKT1 substrate 1 isoform X1
100053005 RPS6KB2; ribosomal protein S6 kinase beta-2
100057481 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
100057875 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
100051258 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
|
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04135 ADRA1A; adrenergic receptor alpha-1A
K07296 ACDC; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K19030 PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K13088 ELAVL1; ELAV-like protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K18341 TBC1D1; TBC1 domain family member 1
K07877 RAB2A; Ras-related protein Rab-2A
K07901 RAB8A; Ras-related protein Rab-8A
K07903 RAB10; Ras-related protein Rab-10
K07905 RAB11B; Ras-related protein Rab-11B
K07881 RAB14; Ras-related protein Rab-14
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
K06259 CD36; CD36 antigen
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
|
04150 mTOR signaling pathway [PATH:ecb04150]
|
04075 Plant hormone signal transduction
|
|
|
Signaling molecules and interaction
|
|
|
Cellular Processes
|
|
|
Organismal Systems
|
|
|
Immune system
|
|
|
Endocrine system
|
04911 Insulin secretion [PATH:ecb04911]
|
04910 Insulin signaling pathway [PATH:ecb04910]
|
111776000 INS; insulin
100066248 INSR; insulin receptor isoform X1
100061987 IRS1; insulin receptor substrate 1
100146249 IRS2; insulin receptor substrate 2 isoform X1
100069009 insulin receptor substrate 1 isoform X1
100059954 IRS4; insulin receptor substrate 4
100052122 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100050227 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
100146348 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100051623 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100058141 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
100051753 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100630736 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
100064671 AKT2; RAC-beta serine/threonine-protein kinase
100054961 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100061130 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100061033 GSK3B; glycogen synthase kinase-3 beta isoform X6
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100071067 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
100058160 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
100059233 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
100062004 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
100146879 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
100055851 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
100062982 PPP1R3B; protein phosphatase 1 regulatory subunit 3B isoform X1
102148031 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
100062942 PPP1R3F; protein phosphatase 1 regulatory subunit 3F isoform X2
100065274 PHKG2; phosphorylase b kinase gamma catalytic chain, liver/testis isoform
100061404 PHKG1; phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform X1
100051530 PHKA2; phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1
100051524 PHKA1; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1
100050040 PHKB; phosphorylase b kinase regulatory subunit beta
100057133 CALML5; calmodulin-like protein 5
100062752 CALM1; calmodulin-1
100070422 calmodulin-like protein 3
100071150 CALM3; calmodulin-3
100629145 CALM2; calmodulin-2
100064482 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6
100052798 CALML4; calmodulin-like protein 4 isoform X2
100057085 PYGB; glycogen phosphorylase, brain form isoform X1
100066726 PYGL; glycogen phosphorylase, liver form
100050345 PYGM; glycogen phosphorylase, muscle form
100071615 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1
100052828 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
100064302 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X3
100146116 PRKAR2A; cAMP-dependent protein kinase type II-alpha regulatory subunit
100060030 PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory subunit
100053143 PRKAR1A; cAMP-dependent protein kinase type I-alpha regulatory subunit
100054262 PRKAR1B; cAMP-dependent protein kinase type I-beta regulatory subunit isoform X1
100069598 LIPE; hormone-sensitive lipase isoform X1
100064240 PRKCZ; protein kinase C zeta type isoform X3
100063737 PRKCI; protein kinase C iota type
100033939 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
100072090 FLOT2; flotillin-2 isoform X1
100050936 FLOT1; flotillin-1 isoform X1
100059630 SH2B adapter protein 2 isoform X1
100061292 SORBS1; sorbin and SH3 domain-containing protein 1 isoform X1
100071403 CBL; E3 ubiquitin-protein ligase CBL isoform X1
100061819 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
100072356 CRK; adapter molecule crk isoform X1
100050855 CRKL; crk-like protein
100069527 RAPGEF1; rap guanine nucleotide exchange factor 1 isoform X8
100068479 RHOQ; rho-related GTP-binding protein RhoQ isoform X1
100059108 EXOC7; exocyst complex component 7 isoform X5
100060571 TRIP10; cdc42-interacting protein 4 isoform X2
100052283 SREBF1; sterol regulatory element-binding protein 1 isoform X1
100071472 ACACA; acetyl-CoA carboxylase 1 isoform X1
100066740 ACACB; acetyl-CoA carboxylase 2 isoform X1
100057311 FASN; fatty acid synthase isoform X4
100063608 PKLR; pyruvate kinase PKLR isoform X1
100068725 HK3; hexokinase-3 isoform X1
100009677 HK2; hexokinase-2
100072687 HK1; hexokinase-1 isoform X2
100072686 HKDC1; putative hexokinase HKDC1
100051836 glucokinase
100034159 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
100009710 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
100034094 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
100034095 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
100034098 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2
100034096 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
100034099 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3
100050481 FOXO1; forkhead box protein O1
100055716 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X3
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100063910 FBP1; fructose-1,6-bisphosphatase 1
100061491 FBP2; fructose-1,6-bisphosphatase isozyme 2
100055710 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
100054903 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2
100051341 MTOR; serine/threonine-protein kinase mTOR isoform X3
100056244 RPTOR; regulatory-associated protein of mTOR isoform X10
100053005 RPS6KB2; ribosomal protein S6 kinase beta-2
100057481 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
100052368 RPS6; 40S ribosomal protein S6
100057875 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
100057254 EIF4E2; eukaryotic translation initiation factor 4E type 2
100066216 EIF4E; eukaryotic translation initiation factor 4E isoform X1
100068758 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X2
100066615 TSC1; hamartin isoform X1
100065679 TSC2; tuberin isoform X2
100064440 RHEB; GTP-binding protein Rheb
100055447 BAD; bcl2-associated agonist of cell death
100063053 SHC1; SHC-transforming protein 1 isoform X2
100146209 SHC2; SHC-transforming protein 2
100061926 SHC3; SHC-transforming protein 3
100055699 SHC4; SHC-transforming protein 4
100051866 GRB2; growth factor receptor-bound protein 2
100053889 SOS1; son of sevenless homolog 1 isoform X1
100066282 SOS2; son of sevenless homolog 2 isoform X1
100055481 HRAS; GTPase HRas isoform X1
100064473 KRAS; GTPase KRas isoform X1
100051785 LOW QUALITY PROTEIN: GTPase KRas-like
100059469 NRAS; GTPase NRas
100061212 ARAF; serine/threonine-protein kinase A-Raf isoform X2
100065760 BRAF; serine/threonine-protein kinase B-raf isoform X2
100051110 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100065996 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
100063190 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100066173 MAPK3; mitogen-activated protein kinase 3
100057701 MAPK1; mitogen-activated protein kinase 1 isoform X2
100064521 MKNK1; MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1
100146117 MKNK2; MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1
100051388 ELK1; ETS domain-containing protein Elk-1
102148488 SOCS1; suppressor of cytokine signaling 1
100051952 SOCS2; suppressor of cytokine signaling 2
100050730 SOCS3; suppressor of cytokine signaling 3
100050301 SOCS4; suppressor of cytokine signaling 4
100052066 PTPN1; tyrosine-protein phosphatase non-receptor type 1
100053205 PTPRF; receptor-type tyrosine-protein phosphatase F isoform X1
100052608 MAPK10; mitogen-activated protein kinase 10 isoform X1
100057961 MAPK9; mitogen-activated protein kinase 9 isoform X1
100051798 MAPK8; mitogen-activated protein kinase 8 isoform X1
100050167 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100066037 INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2
|
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17445 IRS3; insulin receptor substrate 3
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K17453 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07193 APS; SH2B adapter protein 2
K06086 SORBS1; sorbin and SH3 domain containing 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04438 CRK; proto-oncogene C-crk
K04438 CRK; proto-oncogene C-crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K07194 RHOQ; Ras homolog gene family, member Q
K07195 EXOC7; exocyst complex component 7
K07196 TRIP10; thyroid hormone receptor interactor 10
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; Bcl-2-antagonist of cell death
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04375 ELK1; ETS domain-containing protein Elk-1
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
|
04922 Glucagon signaling pathway [PATH:ecb04922]
|
100064671 AKT2; RAC-beta serine/threonine-protein kinase
100054961 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100061130 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100071615 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1
100051551 GCG; glucagon isoform X1
100055316 GCGR; glucagon receptor isoform X1
100056464 guanine nucleotide-binding protein G(s) subunit alpha isoform X1
100071337 ADCY2; adenylate cyclase type 2 isoform X1
100052828 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
100064302 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X3
100066388 CREB1; cyclic AMP-responsive element-binding protein 1
100053304 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1
100070334 ATF4; cyclic AMP-dependent transcription factor ATF-4
100062307 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1
100064828 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
100057002 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1
100067794 CREB3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3
100063153 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
100054803 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1
100061897 serine/threonine-protein phosphatase 4 regulatory subunit 3B
100063171 PPP4R3A; serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1
100066287 PPP4R3B; serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1
100064118 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit
100056571 CRTC2; CREB-regulated transcription coactivator 2 isoform X1
100070391 SIK2; serine/threonine-protein kinase SIK2 isoform X1
100055626 EP300; histone acetyltransferase p300 isoform X2
100069613 CREBBP; CREB-binding protein isoform X1
100055716 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X3
100057456 SIK1; serine/threonine-protein kinase SIK1
100063136 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X1
100057315 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
100051558 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
100055407 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
100051485 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
100052808 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1
100064557 ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1
100053019 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
100057357 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
100067434 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X4
100072862 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
100061874 PPP3R1; calcineurin subunit B type 1
102148270 PPP3R2; calcineurin subunit B type 2
100064138 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X13
100071654 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
100072618 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X6
100146368 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
100050481 FOXO1; forkhead box protein O1
100072571 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X2
100049840 PPARA; peroxisome proliferator-activated receptor alpha
100052097 PRMT1; protein arginine N-methyltransferase 1 isoform X3
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100055710 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
100054903 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2
100009716 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
100055438 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1
100056027 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform isoform X1
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100051530 PHKA2; phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1
100051524 PHKA1; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1
100050040 PHKB; phosphorylase b kinase regulatory subunit beta
100065274 PHKG2; phosphorylase b kinase gamma catalytic chain, liver/testis isoform
100061404 PHKG1; phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform X1
100057133 CALML5; calmodulin-like protein 5
100062752 CALM1; calmodulin-1
100070422 calmodulin-like protein 3
100071150 CALM3; calmodulin-3
100629145 CALM2; calmodulin-2
100064482 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6
100052798 CALML4; calmodulin-like protein 4 isoform X2
100057085 PYGB; glycogen phosphorylase, brain form isoform X1
100066726 PYGL; glycogen phosphorylase, liver form
100050345 PYGM; glycogen phosphorylase, muscle form
100062514 PFKFB1; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X3
100034159 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
100009710 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
100034094 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
100034095 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
100034098 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2
100034096 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
100034099 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3
100071472 ACACA; acetyl-CoA carboxylase 1 isoform X1
100066740 ACACB; acetyl-CoA carboxylase 2 isoform X1
100034080 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
100033974 SLC2A2; solute carrier family 2, facilitated glucose transporter member 2
100051836 glucokinase
100051714 PGAM2; phosphoglycerate mutase 2
100070738 PGAM1; phosphoglycerate mutase 1
100063687 PKM; pyruvate kinase PKM isoform M2
100051597 PDHA1; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
100053606 PDHA2; pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
100050581 PDHB; pyruvate dehydrogenase E1 component subunit beta, mitochondrial
100033997 LDHB; L-lactate dehydrogenase B chain
100057016 LDHA; L-lactate dehydrogenase A chain
100057054 L-lactate dehydrogenase C chain isoform X4
102150999 LOW QUALITY PROTEIN: L-lactate dehydrogenase A-like 6A
102148791 LOW QUALITY PROTEIN: L-lactate dehydrogenase A-like 6A
|
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K05259 GCG; glucagon
K04583 GCGR; glucagon receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K07201 FOXO1; forkhead box protein O1
K11411 SIRT1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
|
04923 Regulation of lipolysis in adipocyte [PATH:ecb04923]
|
04920 Adipocytokine signaling pathway [PATH:ecb04920]
|
03320 PPAR signaling pathway [PATH:ecb03320]
|
04912 GnRH signaling pathway [PATH:ecb04912]
|
04913 Ovarian Steroidogenesis [PATH:ecb04913]
|
04915 Estrogen signaling pathway [PATH:ecb04915]
|
04914 Progesterone-mediated oocyte maturation [PATH:ecb04914]
|
04917 Prolactin signaling pathway [PATH:ecb04917]
|
04921 Oxytocin signaling pathway [PATH:ecb04921]
|
04926 Relaxin signaling pathway [PATH:ecb04926]
|
04918 Thyroid hormone synthesis [PATH:ecb04918]
|
04919 Thyroid hormone signaling pathway [PATH:ecb04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:ecb04928]
|
04916 Melanogenesis [PATH:ecb04916]
|
04924 Renin secretion [PATH:ecb04924]
|
04614 Renin-angiotensin system [PATH:ecb04614]
|
04925 Aldosterone synthesis and secretion [PATH:ecb04925]
|
04927 Cortisol synthesis and secretion [PATH:ecb04927]
|
|
|
Circulatory system
|
|
|
Digestive system
|
|
|
Excretory system
|
|
|
Nervous system
|
|
|
Sensory system
|
|
|
Development
|
|
|
Aging
|
|
|
Environmental adaptation
|
|
|
Human Diseases
|
|
|
Cancers
|
|
|
Immune diseases
|
|
|
Neurodegenerative diseases
|
|
|
Substance dependence
|
|
|
Cardiovascular diseases
|
|
|
Endocrine and metabolic diseases
|
04930 Type II diabetes mellitus [PATH:ecb04930]
|
04940 Type I diabetes mellitus [PATH:ecb04940]
|
04950 Maturity onset diabetes of the young [PATH:ecb04950]
|
04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:ecb04932]
|
04931 Insulin resistance [PATH:ecb04931]
|
111776000 INS; insulin
100058911 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1
100057166 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1
100050176 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1
100072397 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1
100071067 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
100058160 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
100059233 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
100062004 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
100146879 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
100055851 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
100062982 PPP1R3B; protein phosphatase 1 regulatory subunit 3B isoform X1
102148031 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
100066248 INSR; insulin receptor isoform X1
100061987 IRS1; insulin receptor substrate 1
100052066 PTPN1; tyrosine-protein phosphatase non-receptor type 1
100056857 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
100146191 tyrosine-protein phosphatase non-receptor type 11 isoform X1
100053205 PTPRF; receptor-type tyrosine-protein phosphatase F isoform X1
100051623 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100058141 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
100051753 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
100052122 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100050227 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
100146348 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100051341 MTOR; serine/threonine-protein kinase mTOR isoform X3
100053005 RPS6KB2; ribosomal protein S6 kinase beta-2
100057481 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
100069215 PRKCB; protein kinase C beta type isoform X1
100034196 IL6; interleukin-6 precursor
100034011 STAT3; signal transducer and activator of transcription 3
100050730 SOCS3; suppressor of cytokine signaling 3
100061033 GSK3B; glycogen synthase kinase-3 beta isoform X6
100054723 GYS1; glycogen [starch] synthase, muscle
100064264 GYS2; glycogen [starch] synthase, liver
100033834 TNF; tumor necrosis factor
100059548 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
100052608 MAPK10; mitogen-activated protein kinase 10 isoform X1
100057961 MAPK9; mitogen-activated protein kinase 9 isoform X1
100051798 MAPK8; mitogen-activated protein kinase 8 isoform X1
100050167 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100058000 NFKBIA; NF-kappa-B inhibitor alpha
100067894 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X4
100057483 RELA; transcription factor p65
100063339 NOS3; nitric oxide synthase, endothelial
100064240 PRKCZ; protein kinase C zeta type isoform X3
100051815 TBC1D4; TBC1 domain family member 4 isoform X1
100033939 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
100034159 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
100009710 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
100034094 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
100034095 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2
100034098 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2
100034096 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
100034099 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3
100066740 ACACB; acetyl-CoA carboxylase 2 isoform X1
100055438 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform isoform X1
100070188 SLC27A1; long-chain fatty acid transport protein 1 isoform X1
100067009 SLC27A4; long-chain fatty acid transport protein 4
100069953 SLC27A2; very long-chain acyl-CoA synthetase
100146983 SLC27A3; long-chain fatty acid transport protein 3
100051678 SLC27A5; bile acyl-CoA synthetase
100063461 SLC27A6; long-chain fatty acid transport protein 6 isoform X1
100049847 CD36; platelet glycoprotein 4 isoform X1
100070207 PRKCQ; protein kinase C theta type isoform X1
100051333 PRKCD; protein kinase C delta type isoform X1
100070047 PTPA; serine/threonine-protein phosphatase 2A activator
100052283 SREBF1; sterol regulatory element-binding protein 1 isoform X1
100146249 IRS2; insulin receptor substrate 2 isoform X1
100053353 TRIB3; tribbles homolog 3
100057085 PYGB; glycogen phosphorylase, brain form isoform X1
100066726 PYGL; glycogen phosphorylase, liver form
100050345 PYGM; glycogen phosphorylase, muscle form
100050481 FOXO1; forkhead box protein O1
100055710 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
100054903 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2
100052233 G6PC; glucose-6-phosphatase
100062750 G6PC2; glucose-6-phosphatase 2
100064862 G6PC3; glucose-6-phosphatase 3 isoform X1
100033974 SLC2A2; solute carrier family 2, facilitated glucose transporter member 2
100051253 NR1H3; oxysterols receptor LXR-alpha isoform X1
100052399 NR1H2; oxysterols receptor LXR-beta
100060526 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
100052692 MLX; max-like protein X isoform X2
100059888 MLXIPL; carbohydrate-responsive element-binding protein isoform X7
100060001 MLXIP; MLX-interacting protein isoform X1
100009716 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform
100053394 PRKCE; protein kinase C epsilon type isoform X1
100055716 PPARGC1A; peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X3
100049840 PPARA; peroxisome proliferator-activated receptor alpha
100630736 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
100064671 AKT2; RAC-beta serine/threonine-protein kinase
100054961 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100061130 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
100062388 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100060245 MGEA5; protein O-GlcNAcase isoform X1
100056148 OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1
100034080 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
100067002 GFPT2; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
100061157 GFPT1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1
100056571 CRTC2; CREB-regulated transcription coactivator 2 isoform X1
100066388 CREB1; cyclic AMP-responsive element-binding protein 1
100062307 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1
100064828 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
100057002 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1
100067794 CREB3; LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3
100063153 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
100054803 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1
|
K04526 INS; insulin
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K05405 IL6; interleukin 6
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3; suppressor of cytokine signaling 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K17902 TBC1D4; TBC1 domain family member 4
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
K08748 SLC27A5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K08749 SLC27A6; solute carrier family 27 (fatty acid transporter), member 6
K06259 CD36; CD36 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K17605 PPP2R4; serine/threonine-protein phosphatase 2A activator
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K07187 IRS2; insulin receptor substrate 2
K19518 TRIB3; tribbles homolog 3
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K07201 FOXO1; forkhead box protein O1
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K08536 NR1H3; liver X receptor alpha
K08535 NR1H2; liver X receptor beta
K17962 PPARGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K15719 NCOAT; protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]
K09667 OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K00820 glmS; glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
K00820 glmS; glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ecb04933]
|
04934 Cushing's syndrome [PATH:ecb04934]
|
|
|
Infectious diseases
|
|
|
Drug resistance
|
KEGG Orthology (KO) - Equus caballus (horse)