KEGG Orthology (KO) - Escherichia coli SMS-3-5 (environmental)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
     00730 Thiamine metabolism [PATH:ecm00730]
     00740 Riboflavin metabolism [PATH:ecm00740]
     00750 Vitamin B6 metabolism [PATH:ecm00750]
     00760 Nicotinate and nicotinamide metabolism [PATH:ecm00760]
     00770 Pantothenate and CoA biosynthesis [PATH:ecm00770]
     00780 Biotin metabolism [PATH:ecm00780]
     00785 Lipoic acid metabolism [PATH:ecm00785]
     00790 Folate biosynthesis [PATH:ecm00790]
       EcSMS35_2300 folE; GTP cyclohydrolase I
       EcSMS35_0413 phoA; alkaline phosphatase
       EcSMS35_1321 nudB; dATP pyrophosphohydrolase
       EcSMS35_3351 folB; dihydroneopterin aldolase
       EcSMS35_0153 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
       EcSMS35_3473 folP; dihydropteroate synthase
       EcSMS35_A0127 sul2; dihydropteroate synthase type-2
       EcSMS35_0050 folA; dihydrofolate reductase
       EcSMS35_A0121 dhfrV; dihydrofolate reductase type 5
       EcSMS35_2471 folC; tetrahydrofolate synthase/dihydrofolate synthase
       EcSMS35_1852 ribA; GTP cyclohydrolase II
       EcSMS35_3642 pabA; aminodeoxychorismate synthase, component II
       EcSMS35_1376 pabB; aminodeoxychorismate synthase
       EcSMS35_2031 pabC; aminodeoxychorismate lyase
       EcSMS35_2459 folX; D-erythro-7,8-dihydroneopterin triphosphate epimerase
       EcSMS35_1592 oxidoreductase, short chain dehydrogenase/reductase family
       EcSMS35_2894 queD; queuosine biosynthesis protein QueD
       EcSMS35_2910 conserved hypothetical protein
       EcSMS35_0487 queC; queuosine biosynthesis protein QueC
       EcSMS35_2934 queF; queuine synthase
       EcSMS35_0804 moaA; molybdenum cofactor biosynthesis protein A
       EcSMS35_0806 moaC; molybdenum cofactor biosynthesis protein C
       EcSMS35_0808 moaE; molybdopterin converting factor, subunit 2
       EcSMS35_0008 mog; molybdopterin biosynthesis protein Mog
       EcSMS35_0805 moaB; molybdenum cofactor biosynthesis protein B
       EcSMS35_0852 moeA; molybdopterin biosynthesis protein MoeA
       EcSMS35_3010 conserved hypothetical protein
       EcSMS35_4238 mobA; molybdopterin-guanine dinucleotide biosynthesis protein A
K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K08310 nudB; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]
K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
K18824 sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85]
K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
K07589 folX; D-erythro-7,8-dihydroneopterin triphosphate epimerase [EC:5.1.99.7]
K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
     00670 One carbon pool by folate [PATH:ecm00670]
       EcSMS35_0050 folA; dihydrofolate reductase
       EcSMS35_A0121 dhfrV; dihydrofolate reductase type 5
       EcSMS35_1592 oxidoreductase, short chain dehydrogenase/reductase family
       EcSMS35_0574 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
       EcSMS35_2704 glyA; serine hydroxymethyltransferase
       EcSMS35_2648 purN; phosphoribosylglycinamide formyltransferase
       EcSMS35_4455 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
       EcSMS35_3583 fmt; methionyl-tRNA formyltransferase
       EcSMS35_3037 gcvT; glycine cleavage system T protein
       EcSMS35_4472 metH; methionine synthase
       EcSMS35_2974 thyA; thymidylate synthase
       EcSMS35_1909 purU; formyltetrahydrofolate deformylase
       EcSMS35_4389 metF; 5,10-methylenetetrahydrofolate reductase
       EcSMS35_3045 5,10-methenyltetrahydrofolate synthetase
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
     00830 Retinol metabolism
     00860 Porphyrin metabolism [PATH:ecm00860]
     00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:ecm00130]
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
     02000 Transporters [BR:ecm02000]
     02044 Secretion system [BR:ecm02044]
     02042 Bacterial toxins [BR:ecm02042]
     02022 Two-component system [BR:ecm02022]
     02035 Bacterial motility proteins [BR:ecm02035]
     03037 Cilium and associated proteins
     04812 Cytoskeleton proteins [BR:ecm04812]
     04147 Exosome [BR:ecm04147]
     02048 Prokaryotic defense system [BR:ecm02048]
     04030 G protein-coupled receptors
     04050 Cytokine receptors
     04054 Pattern recognition receptors
     03310 Nuclear receptors
     04040 Ion channels [BR:ecm04040]
     04031 GTP-binding proteins
     04052 Cytokines and neuropeptides
     04515 Cell adhesion molecules
     04090 CD molecules [BR:ecm04090]
     01504 Antimicrobial resistance genes [BR:ecm01504]
       EcSMS35_A0130 blaT; beta-lactamase TEM
       EcSMS35_A0135 aadA; aminoglycoside adenylyltransferase
       EcSMS35_A0159 aminoglycoside 3'-phosphotransferase
       EcSMS35_A0128 strA; aminoglycoside resistance protein A
       EcSMS35_A0129 strB; aminoglycoside resistance protein B
       EcSMS35_A0153 tetA; tetracycline resistance protein, class A
       EcSMS35_0869 mdfA; multidrug translocase MdfA
       EcSMS35_A0117 cmlA; chloramphenicol acetyltransferase 2
       EcSMS35_A0127 sul2; dihydropteroate synthase type-2
       EcSMS35_A0121 dhfrV; dihydrofolate reductase type 5
       EcSMS35_0587 cusS; sensor kinase CusS
       EcSMS35_0588 cusR; transcriptional regulatory protein CusR
       EcSMS35_1685 ddpX; D-alanyl-D-alanine dipeptidase
       EcSMS35_1996 phoQ; sensor histidine kinase PhoQ
       EcSMS35_1995 phoP; DNA-binding response regulator PhoP
       EcSMS35_1836 eefA; multidrug efflux transport protein EefA
       EcSMS35_0506 acrA; acriflavine resistance protein A
       EcSMS35_0505 acriflavine resistance protein B
       EcSMS35_1835 eefB; multidrug efflux transport protein EefB
       EcSMS35_1834 eefC; multidrug efflux outer membrane protein EefC
       EcSMS35_0530 cueR; Cu(I)-responsive transcriptional regulator
       EcSMS35_3559 putative transcriptional regulator EnvR
       EcSMS35_3560 acrE; acriflavine resistance protein E
       EcSMS35_3330 tolC; outer membrane protein TolC
       EcSMS35_2519 evgA; positive transcription regulator EvgS
       EcSMS35_3816 mdtE; multidrug resistance protein MdtE
       EcSMS35_3817 mdtF; multidrug resistance protein MdtF
       EcSMS35_1639 marA; multiple antibiotic resistance protein MarA
       EcSMS35_2191 ompF; outer membrane protein F
K18698 blaTEM; beta-lactamase class A TEM [EC:3.5.2.6]
K00984 aadA; streptomycin 3"-adenylyltransferase [EC:2.7.7.47]
K19272 aph3-I; aminoglycoside 3'-phosphotransferase I [EC:2.7.1.95]
K10673 strA; streptomycin 3"-kinase [EC:2.7.1.87]
K04343 strB; streptomycin 6-kinase [EC:2.7.1.72]
K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
K08160 mdfA; MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein
K19271 catA; chloramphenicol O-acetyltransferase type A [EC:2.3.1.28]
K18824 sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
K07660 phoP; two-component system, OmpR family, response regulator PhoP
K03585 acrA; membrane fusion protein, multidrug efflux system
K03585 acrA; membrane fusion protein, multidrug efflux system
K18138 acrB; multidrug efflux pump
K18138 acrB; multidrug efflux pump
K18139 oprM; outer membrane protein, multidrug efflux system
K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
K18140 envR; TetR/AcrR family transcriptional regulator, acrEF/envCD operon repressor
K18141 acrE; membrane fusion protein, multidrug efflux system
K12340 tolC; outer membrane protein
K07690 evgA; two-component system, NarL family, response regulator EvgA
K18898 mdtE; membrane fusion protein, multidrug efflux system
K18899 mdtF; multidrug efflux pump
K13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator
K09476 ompF; outer membrane pore protein F
     00535 Proteoglycans
     00536 Glycosaminoglycan binding proteins
     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ecm00537]
     04091 Lectins
     04990 Domain-containing proteins not elsewhere classified
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: April 23, 2024