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KO |
09100 Metabolism
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09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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00730 Thiamine metabolism [PATH:efa00730]
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EF2775 thiD; phosphomethylpyrimidine kinase
EF0371 class V aminotransferase
EF2072 class V aminotransferase
EF2934 thiI; thiazole biosynthesis protein ThiI
EF2777 hydroxyethylthiazole kinase
EF2776 thiE; thiamine-phosphate pyrophosphorylase
EF3119 hypothetical protein
EF2973 phoZ; alkaline phosphatase
EF3117 thiamin pyrophosphokinase
EF0228 adk; adenylate kinase
EF2767 transcriptional regulator
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K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
K00878 thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]
K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
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00740 Riboflavin metabolism [PATH:efa00740]
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00750 Vitamin B6 metabolism [PATH:efa00750]
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00760 Nicotinate and nicotinamide metabolism [PATH:efa00760]
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00770 Pantothenate and CoA biosynthesis [PATH:efa00770]
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00780 Biotin metabolism [PATH:efa00780]
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00785 Lipoic acid metabolism [PATH:efa00785]
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00790 Folate biosynthesis [PATH:efa00790]
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EF3267 folE; GTP cyclohydrolase I
EF2973 phoZ; alkaline phosphatase
EF3269 folB; dihydroneopterin aldolase
EF3268 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EF3265 folP; dihydropteroate synthase
EF1577 folA; dihydrofolate reductase
EF2928 bifunctional folylpolyglutamate synthase/dihydrofolate synthase family protein
EF1393 molybdopterin cofactor biosynthesis protein A
EF1392 moaC; molybdenum cofactor biosynthesis protein MoaC
EF1391 molybdenum cofactor biosynthesis family protein
EF2569 hypothetical protein
EF1385 molybdopterin-guanine dinucleotide biosynthesis protein A
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K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
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00670 One carbon pool by folate [PATH:efa00670]
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00830 Retinol metabolism
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00860 Porphyrin metabolism [PATH:efa00860]
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00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:efa00130]
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:efa02020]
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EF1704 sensory box histidine kinase
EF1703 phoP; alkaline phosphatase synthesis transcriptional regulatory protein PhoP
EF2973 phoZ; alkaline phosphatase
EF1759 phosphate ABC transporter substrate-binding protein
EF1705 phosphate-binding protein
EF3027 htrA; serine protease DO
EF0570 kdpD; sensor histidine kinase KdpD
EF0571 DNA-binding response regulator
EF0567 kdpA; potassium-transporting ATPase subunit A
EF0568 kdpB; potassium-transporting ATPase subunit B
EF0569 kdpC; potassium-transporting ATPase subunit C
EF1194 vicK; sensory box histidine kinase VicK
EF1193 vicR; DNA-binding response regulator VicR
EF2630 transcriptional regulator
EF0001 dnaA; chromosomal replication initiation protein
EF2752 ABC transporter ATP-binding protein
EF2751 permease
EF0927 sensor histidine kinase
EF0926 DNA-binding response regulator
EF2749 D-alanine--poly(phosphoribitol) ligase subunit 1
EF2748 dtlB; basic membrane protein DtlB
EF2747 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2
EF2746 dltD; dltD protein
EF0031 hypothetical protein
EF2050 ABC transporter ATP-binding protein
EF2049 ABC transporter permease
EF2298 vanSB; sensor histidine kinase VanSB
EF2299 vanRB; DNA-binding response regulator VanRB
EF2294 vanB; D-alanine--D-lactate ligase
EF2295 D-specific alpha-keto acid dehydrogenase
EF2293 vanX; D-alanyl-D-alanine dipeptidase
EF2297 vanYB; D-alanyl-D-alanine carboxypeptidase
EF2296 vanW; vancomycin B-type resistance protein VanW
EF1051 sensor histidine kinase
EF1050 DNA-binding response regulator
EF3322 citC; [citrate (pro-3S)-lyase] ligase
EF3321 citD; citrate lyase subunit gamma
EF3320 citE; citrate lyase subunit beta
EF3319 citF; citrate lyase subunit alpha
EF3318 citX; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EF3315 triphosphoribosyl-dephospho-CoA synthase
EF3316 malic enzyme family protein
EF1206 malate dehydrogenase, decarboxylating
EF1207 CCS family citrate carrier protein
EF3197 sensor histidine kinase
EF3196 response regulator
EF3194 murein hydrolase regulator LrgA
EF3193 antiholin-like protein LrgB
EF1821 agrBfs; agrBfs protein
EF1820 histidine kinase
EF1822 response regulator
EF2912 sensor histidine kinase
EF2911 LuxR family DNA-binding response regulator
EF2913 hypothetical protein
EF2159 glnA; glutamine synthetase, type I
EF0782 rpoN; RNA polymerase factor sigma-54
EF2219 sensor histidine kinase
EF2218 AraC family transcriptional regulator
EF2061 cydA; cytochrome d ubiquinol oxidase subunit I
EF2060 cydB; cytochrome d ubiquinol oxidase subunit II
EF3058 phosphotyrosine protein phosphatase
EF2917 UDP-N-acetylglucosamine 2-epimerase
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K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K02040 pstS; phosphate transport system substrate-binding protein
K02040 pstS; phosphate transport system substrate-binding protein
K04771 degP; serine protease Do [EC:3.4.21.107]
K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
K01548 kdpC; potassium-transporting ATPase KdpC subunit
K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
K07668 vicR; two-component system, OmpR family, response regulator VicR
K07668 vicR; two-component system, OmpR family, response regulator VicR
K02313 dnaA; chromosomal replication initiator protein
K11631 bceA; bacitracin transport system ATP-binding protein
K11632 bceB; bacitracin transport system permease protein
K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR
K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
K03739 dltB; membrane protein involved in D-alanine export
K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
K03740 dltD; D-alanine transfer protein
K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]
K11635 yxdL; putative ABC transport system ATP-binding protein
K11636 yxdM; putative ABC transport system permease protein
K18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
K18344 vanRB; two-component system, OmpR family, response regulator VanR
K15739 vanB; D-alanine---(R)-lactate ligase [EC:6.1.2.1]
K18347 vanH; D-specific alpha-keto acid dehydrogenase [EC:1.1.1.-]
K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
K18346 vanW; vancomycin resistance protein VanW
K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
K18941 arlR; two-component system, OmpR family, response regulator ArlR
K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]
K01646 citD; citrate lyase subunit gamma (acyl carrier protein)
K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10]
K05964 citX; holo-ACP synthase [EC:2.7.7.61]
K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
K11616 maeN; malate:Na+ symporter
K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
K07705 lytT; two-component system, LytTR family, response regulator LytT
K05338 lrgA; holin-like protein
K05339 lrgB; holin-like protein LrgB
K07813 agrB; accessory gene regulator B
K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
K07707 agrA; two-component system, LytTR family, response regulator AgrA
K11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
K11618 liaR; two-component system, NarL family, response regulator LiaR
K11622 liaF; lia operon protein LiaF
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K03092 rpoN; RNA polymerase sigma-54 factor
K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
K07720 yesN; two-component system, response regulator YesN
K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
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04010 MAPK signaling pathway
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway
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04014 Ras signaling pathway
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04015 Rap1 signaling pathway
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04310 Wnt signaling pathway
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04330 Notch signaling pathway
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04340 Hedgehog signaling pathway
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway
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04390 Hippo signaling pathway
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species
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04370 VEGF signaling pathway
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04371 Apelin signaling pathway
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04630 JAK-STAT signaling pathway
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04064 NF-kappa B signaling pathway
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04668 TNF signaling pathway
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04066 HIF-1 signaling pathway
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04068 FoxO signaling pathway
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04020 Calcium signaling pathway
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04070 Phosphatidylinositol signaling system
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04072 Phospholipase D signaling pathway
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04071 Sphingolipid signaling pathway
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04024 cAMP signaling pathway
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04022 cGMP-PKG signaling pathway
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04151 PI3K-Akt signaling pathway
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04152 AMPK signaling pathway
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04150 mTOR signaling pathway
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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02000 Transporters [BR:efa02000]
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02044 Secretion system [BR:efa02044]
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02042 Bacterial toxins [BR:efa02042]
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02022 Two-component system [BR:efa02022]
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02035 Bacterial motility proteins
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03037 Cilium and associated proteins
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04812 Cytoskeleton proteins [BR:efa04812]
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04147 Exosome [BR:efa04147]
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EF1961 eno; enolase
EF1526 gap-1; glyceraldehyde 3-phosphate dehydrogenase
EF1964 gap-2; glyceraldehyde-3-phosphate dehydrogenase
EF1963 pgk; phosphoglycerate kinase
EF1046 pyk; pyruvate kinase
EF1534 cyclophilin type peptidyl-prolyl cis-trans isomerase
EF2633 groEL; chaperonin, 60 kDa
EF1308 dnaK; dnak protein
EF1416 pgi; glucose-6-phosphate isomerase
EF3293 guaB; inosine 5'-monophosphate dehydrogenase
EF0201 tuf; elongation factor Tu
EF0687 HIT family protein
EF0255 ldh; L-lactate dehydrogenase
EF0641 ldh-2; L-lactate dehydrogenase
EF0228 adk; adenylate kinase
EF1687 apt; adenine phosphoribosyltransferase
EF2580 phenylhydantoinase
EF1069 galK; galactokinase
EF1929 glpK; glycerol kinase
EF2159 glnA; glutamine synthetase, type I
EF2973 phoZ; alkaline phosphatase
EF1778 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
EF1356 lpdA; dihydrolipoamide dehydrogenase
EF1661 bkdD; branched-chain alpha-keto acid dehydrogenase, E3 component, dihydrolipoamide dehydrogenase
EF1004 zwf; glucose-6-phosphate 1-dehydrogenase
EF1962 tpiA; triosephosphate isomerase
EF0195 gpm; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
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K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
K04043 dnaK; molecular chaperone DnaK
K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K02358 tuf; elongation factor Tu
K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
K00849 galK; galactokinase [EC:2.7.1.6]
K00864 glpK; glycerol kinase [EC:2.7.1.30]
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
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02048 Prokaryotic defense system [BR:efa02048]
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04030 G protein-coupled receptors
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04050 Cytokine receptors
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04054 Pattern recognition receptors
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03310 Nuclear receptors
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04040 Ion channels [BR:efa04040]
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04031 GTP-binding proteins
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04052 Cytokines and neuropeptides
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04515 Cell adhesion molecules
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04090 CD molecules [BR:efa04090]
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01504 Antimicrobial resistance genes [BR:efa01504]
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00535 Proteoglycans
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00536 Glycosaminoglycan binding proteins
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:efa00537]
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EF2973 phoZ; alkaline phosphatase
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K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
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04091 Lectins
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04990 Domain-containing proteins not elsewhere classified
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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