KEGG Orthology (KO) - Escherichia coli O104:H4 2009EL-2050 (EAEC)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
     00730 Thiamine metabolism [PATH:esm00730]
     00740 Riboflavin metabolism [PATH:esm00740]
     00750 Vitamin B6 metabolism [PATH:esm00750]
     00760 Nicotinate and nicotinamide metabolism [PATH:esm00760]
     00770 Pantothenate and CoA biosynthesis [PATH:esm00770]
     00780 Biotin metabolism [PATH:esm00780]
     00785 Lipoic acid metabolism [PATH:esm00785]
     00790 Folate biosynthesis [PATH:esm00790]
       O3M_08630 folE; GTP cyclohydrolase I
       O3M_19580 alkaline phosphatase
       O3M_10580 nudB; dihydroneopterin triphosphate pyrophosphatase
       O3M_03700 folB; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase
       O3M_20755 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase
       O3M_03100 folP; dihydropteroate synthase
       O3M_00545 dihydropteroate synthase
       O3M_00480 dihydropteroate synthase
       O3M_21205 folA; dihydrofolate reductase
       O3M_00535 dihydrofolate reductase
       O3M_07870 bifunctional folylpolyglutamate synthase/dihydrofolate synthase
       O3M_13930 ribA; GTP cyclohydrolase II
       O3M_02310 para-aminobenzoate synthase component II
       O3M_10860 pabB; aminodeoxychorismate synthase subunit I
       O3M_15055 4-amino-4-deoxychorismate lyase
       O3M_07930 folX; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
       O3M_12170 dihydromonapterin reductase
       O3M_05740 6-pyruvoyl tetrahydrobiopterin synthase
       O3M_05680 hypothetical protein
       O3M_19245 queuosine biosynthesis protein QueC
       O3M_05570 queF; 7-cyano-7-deazaguanine reductase
       O3M_17425 moaA; molybdenum cofactor biosynthesis protein A
       O3M_17415 moaC; molybdenum cofactor biosynthesis protein MoaC
       O3M_17405 moaE; molybdopterin guanine dinucleotide biosynthesis protein MoaE
       O3M_21395 mogA; molybdenum cofactor biosynthesis protein MogA
       O3M_17420 molybdenum cofactor biosynthesis protein B
       O3M_17185 molybdopterin biosynthesis protein MoeA
       O3M_05125 hypothetical protein
       O3M_24525 mobA; molybdopterin-guanine dinucleotide biosynthesis protein MobA
K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K08310 nudB; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]
K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
K18974 sul1; dihydropteroate synthase type 1 [EC:2.5.1.15]
K18824 sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85]
K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
K07589 folX; D-erythro-7,8-dihydroneopterin triphosphate epimerase [EC:5.1.99.7]
K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]
K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
     00670 One carbon pool by folate [PATH:esm00670]
       O3M_21205 folA; dihydrofolate reductase
       O3M_00535 dihydrofolate reductase
       O3M_12170 dihydromonapterin reductase
       O3M_18830 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
       O3M_06705 glyA; serine hydroxymethyltransferase
       O3M_06965 purN; phosphoribosylglycinamide formyltransferase
       O3M_23745 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
       O3M_02610 fmt; methionyl-tRNA formyltransferase
       O3M_04985 gcvT; glycine cleavage system aminomethyltransferase T
       O3M_23705 metH; B12-dependent methionine synthase
       O3M_05420 thyA; thymidylate synthase
       O3M_14470 purU; formyltetrahydrofolate deformylase
       O3M_24045 metF; 5,10-methylenetetrahydrofolate reductase
       O3M_04955 5-formyltetrahydrofolate cyclo-ligase family protein
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K13938 folM; dihydromonapterin reductase / dihydrofolate reductase [EC:1.5.1.50 1.5.1.3]
K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
     00830 Retinol metabolism
     00860 Porphyrin metabolism [PATH:esm00860]
     00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:esm00130]
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
     02000 Transporters [BR:esm02000]
     02044 Secretion system [BR:esm02044]
     02042 Bacterial toxins [BR:esm02042]
     02022 Two-component system [BR:esm02022]
     02035 Bacterial motility proteins [BR:esm02035]
     03037 Cilium and associated proteins
     04812 Cytoskeleton proteins [BR:esm04812]
     04147 Exosome [BR:esm04147]
     02048 Prokaryotic defense system [BR:esm02048]
     04030 G protein-coupled receptors
     04050 Cytokine receptors
     04054 Pattern recognition receptors
     03310 Nuclear receptors
     04040 Ion channels [BR:esm04040]
     04031 GTP-binding proteins
     04052 Cytokines and neuropeptides
     04515 Cell adhesion molecules
     04090 CD molecules [BR:esm04090]
     01504 Antimicrobial resistance genes [BR:esm01504]
       O3M_00505 beta-lactamase TEM
       O3M_00475 hypothetical protein
       O3M_00470 streptomycin phosphotransferase
       O3M_00390 tetracycline efflux protein
       O3M_17110 multidrug efflux system translocase MdfA
       O3M_13235 putative acetyltransferase
       O3M_00545 dihydropteroate synthase
       O3M_00480 dihydropteroate synthase
       O3M_00535 dihydrofolate reductase
       O3M_01555 sensor kinase CusS
       O3M_01640 sensor protein pcoS
       O3M_18740 sensor kinase CusS
       O3M_01560 DNA-binding transcriptional activator CusR
       O3M_01635 Transcriptional regulatory protein pcoR
       O3M_18735 DNA-binding transcriptional activator CusR
       O3M_13020 D-alanyl-D-alanine dipeptidase
       O3M_14890 sensor protein PhoQ
       O3M_14885 DNA-binding transcriptional regulator PhoP
       O3M_19155 multidrug efflux system transporter AcrA
       O3M_19160 multidrug efflux system protein AcrB
       O3M_19030 DNA-binding transcriptional regulator CueR
       O3M_02690 DNA-binding transcriptional regulator EnvR
       O3M_02685 hypothetical protein
       O3M_02680 acriflavine resistance protein
       O3M_03805 tolC; outer membrane channel protein
       O3M_07575 DNA-binding transcriptional activator EvgA
       O3M_01360 multidrug efflux system protein MdtE
       O3M_01355 multidrug transporter MdtF, RpoS-dependent
       O3M_12780 DNA-binding transcriptional activator MarA
       O3M_16670 outer membrane protein F
K18698 blaTEM; beta-lactamase class A TEM [EC:3.5.2.6]
K10673 strA; streptomycin 3"-kinase [EC:2.7.1.87]
K04343 strB; streptomycin 6-kinase [EC:2.7.1.72]
K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
K08160 mdfA; MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein
K18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-]
K18974 sul1; dihydropteroate synthase type 1 [EC:2.5.1.15]
K18824 sul2; dihydropteroate synthase type 2 [EC:2.5.1.15]
K18589 dfrA1; dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
K07660 phoP; two-component system, OmpR family, response regulator PhoP
K03585 acrA; membrane fusion protein, multidrug efflux system
K18138 acrB; multidrug efflux pump
K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
K18140 envR; TetR/AcrR family transcriptional regulator, acrEF/envCD operon repressor
K18141 acrE; membrane fusion protein, multidrug efflux system
K18142 acrF; multidrug efflux pump
K12340 tolC; outer membrane protein
K07690 evgA; two-component system, NarL family, response regulator EvgA
K18898 mdtE; membrane fusion protein, multidrug efflux system
K18899 mdtF; multidrug efflux pump
K13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator
K09476 ompF; outer membrane pore protein F
     00535 Proteoglycans
     00536 Glycosaminoglycan binding proteins
     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:esm00537]
     04091 Lectins
     04990 Domain-containing proteins not elsewhere classified
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

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Last updated: April 17, 2024