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KO |
09100 Metabolism
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09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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00730 Thiamine metabolism [PATH:fca00730]
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00740 Riboflavin metabolism [PATH:fca00740]
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00750 Vitamin B6 metabolism [PATH:fca00750]
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00760 Nicotinate and nicotinamide metabolism [PATH:fca00760]
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00770 Pantothenate and CoA biosynthesis [PATH:fca00770]
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00780 Biotin metabolism [PATH:fca00780]
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00785 Lipoic acid metabolism [PATH:fca00785]
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00790 Folate biosynthesis [PATH:fca00790]
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101092120 GCH1; GTP cyclohydrolase 1 isoform X1
727689 ALPL; alkaline phosphatase, tissue-nonspecific isozyme precursor
101083873 ALPI; intestinal-type alkaline phosphatase
101087964 DHFR; dihydrofolate reductase isoform X1
101092966 FPGS; folylpolyglutamate synthase, mitochondrial isoform X2
101100943 GGH; gamma-glutamyl hydrolase
101096347 PTS; 6-pyruvoyl tetrahydrobiopterin synthase
101101210 SPR; sepiapterin reductase
101095406 AKR1B1; aldo-keto reductase family 1 member B1
101084388 carbonyl reductase [NADPH] 1
101083875 carbonyl reductase [NADPH] 1-like
101084134 carbonyl reductase [NADPH] 1-like
105260891 carbonyl reductase [NADPH] 1-like
102901316 carbonyl reductase [NADPH] 1-like
100510801 AKR1C3; prostaglandin F synthase 1 isoform X2
101087576 QDPR; dihydropteridine reductase
101100920 PCBD1; pterin-4-alpha-carbinolamine dehydratase isoform X3
101086943 PCBD2; pterin-4-alpha-carbinolamine dehydratase 2 isoform X3
109492504 pterin-4-alpha-carbinolamine dehydratase-like
101081741 PAH; phenylalanine-4-hydroxylase
101090720 TH; tyrosine 3-monooxygenase
101098575 TPH1; tryptophan 5-hydroxylase 1 isoform X2
101082165 TPH2; tryptophan 5-hydroxylase 2
101086723 MOCS1; molybdenum cofactor biosynthesis protein 1 isoform X4
101089492 MOCS2; molybdopterin synthase catalytic subunit
101096816 GPHN; gephyrin isoform X2
101098093 MOCOS; molybdenum cofactor sulfurase isoform X1
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K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K01930 FPGS; folylpolyglutamate synthase [EC:6.3.2.17]
K01307 GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
K00072 SPR; sepiapterin reductase [EC:1.1.1.153]
K00011 AKR1B; aldehyde reductase [EC:1.1.1.21]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00357 QDPR; dihydropteridine reductase [EC:1.5.1.34]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K20967 MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC:4.1.99.22 4.6.1.17]
K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
K15376 GPHN; gephyrin [EC:2.10.1.1 2.7.7.75]
K15631 ABA3; molybdenum cofactor sulfurtransferase [EC:2.8.1.9]
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00670 One carbon pool by folate [PATH:fca00670]
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101087964 DHFR; dihydrofolate reductase isoform X1
101082751 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X4
101086816 MTHFD1; C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
101083836 MTHFD2; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
101093354 MTHFD2L; probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1
101091290 SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1
101086266 SHMT1; serine hydroxymethyltransferase, cytosolic
101087772 GART; trifunctional purine biosynthetic protein adenosine-3
101081485 ATIC; bifunctional purine biosynthesis protein ATIC
101080907 FTCD; formimidoyltransferase-cyclodeaminase isoform X1
101085804 MTFMT; methionyl-tRNA formyltransferase, mitochondrial
101084781 AMT; aminomethyltransferase, mitochondrial
101101166 MTR; methionine synthase isoform X3
101091231 TYMS; thymidylate synthase
101091432 ALDH1L1; cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X1
101088592 ALDH1L2; mitochondrial 10-formyltetrahydrofolate dehydrogenase
101100576 MTHFR; methylenetetrahydrofolate reductase isoform X2
101093689 5-formyltetrahydrofolate cyclo-ligase isoform X1
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K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K13402 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
K00288 MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K13403 MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
K13403 MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K00289 ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K00289 ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K25004 MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
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00830 Retinol metabolism [PATH:fca00830]
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00860 Porphyrin metabolism [PATH:fca00860]
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00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:fca00130]
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09161 Cancer: overview
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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01521 EGFR tyrosine kinase inhibitor resistance [PATH:fca01521]
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01524 Platinum drug resistance [PATH:fca01524]
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01523 Antifolate resistance [PATH:fca01523]
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101084221 FOLR1; folate receptor alpha
101084733 folate receptor gamma-like
101095853 FOLR2; folate receptor beta
101086247 SLC19A1; reduced folate transporter isoform X3
101100096 SLC46A1; proton-coupled folate transporter
101092966 FPGS; folylpolyglutamate synthase, mitochondrial isoform X2
101100943 GGH; gamma-glutamyl hydrolase
101091231 TYMS; thymidylate synthase
101087964 DHFR; dihydrofolate reductase isoform X1
101091290 SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1
101086266 SHMT1; serine hydroxymethyltransferase, cytosolic
101100576 MTHFR; methylenetetrahydrofolate reductase isoform X2
101094304 polyunsaturated fatty acid lipoxygenase ALOX12 isoform X2
101087772 GART; trifunctional purine biosynthetic protein adenosine-3
101081485 ATIC; bifunctional purine biosynthesis protein ATIC
101095617 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
101086544 IKBKG; NF-kappa-B essential modulator isoform X1
100142683 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
101096604 RELA; transcription factor p65
493755 TNF; tumor necrosis factor precursor
768274 IL1B; interleukin-1 beta
493687 IL6; interleukin-6 precursor
101101279 ABCC1; multidrug resistance-associated protein 1 isoform X3
101085924 ABCC2; ATP-binding cassette sub-family C member 2 isoform X1
101098502 ABCC3; LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 3
101096129 ABCC4; ATP-binding cassette sub-family C member 4 isoform X1
101090542 ABCC5; multidrug resistance-associated protein 5 isoform X2
101094017 ABCG2; broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1
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K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K14609 SLC19A1; solute carrier family 19 (folate transporter), member 1
K14613 SLC46A1; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
K01930 FPGS; folylpolyglutamate synthase [EC:6.3.2.17]
K01307 GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K25004 MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
K00458 ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K05667 ABCC3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K05668 ABCC5; ATP-binding cassette, subfamily C (CFTR/MRP), member 5
K05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2
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01522 Endocrine resistance [PATH:fca01522]
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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