KEGG Orthology (KO) - Felis catus (domestic cat)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
     00730 Thiamine metabolism [PATH:fca00730]
     00740 Riboflavin metabolism [PATH:fca00740]
     00750 Vitamin B6 metabolism [PATH:fca00750]
     00760 Nicotinate and nicotinamide metabolism [PATH:fca00760]
     00770 Pantothenate and CoA biosynthesis [PATH:fca00770]
     00780 Biotin metabolism [PATH:fca00780]
     00785 Lipoic acid metabolism [PATH:fca00785]
     00790 Folate biosynthesis [PATH:fca00790]
       101092120 GCH1; GTP cyclohydrolase 1 isoform X1
       727689 ALPL; alkaline phosphatase, tissue-nonspecific isozyme precursor
       101083873 ALPI; intestinal-type alkaline phosphatase
       101087964 DHFR; dihydrofolate reductase isoform X1
       101092966 FPGS; folylpolyglutamate synthase, mitochondrial isoform X2
       101100943 GGH; gamma-glutamyl hydrolase
       101096347 PTS; 6-pyruvoyl tetrahydrobiopterin synthase
       101101210 SPR; sepiapterin reductase
       101095406 AKR1B1; aldo-keto reductase family 1 member B1
       101084388 carbonyl reductase [NADPH] 1
       101083875 carbonyl reductase [NADPH] 1-like
       101084134 carbonyl reductase [NADPH] 1-like
       105260891 carbonyl reductase [NADPH] 1-like
       102901316 carbonyl reductase [NADPH] 1-like
       100510801 AKR1C3; prostaglandin F synthase 1 isoform X2
       101087576 QDPR; dihydropteridine reductase
       101100920 PCBD1; pterin-4-alpha-carbinolamine dehydratase isoform X3
       101086943 PCBD2; pterin-4-alpha-carbinolamine dehydratase 2 isoform X3
       109492504 pterin-4-alpha-carbinolamine dehydratase-like
       101081741 PAH; phenylalanine-4-hydroxylase
       101090720 TH; tyrosine 3-monooxygenase
       101098575 TPH1; tryptophan 5-hydroxylase 1 isoform X2
       101082165 TPH2; tryptophan 5-hydroxylase 2
       101086723 MOCS1; molybdenum cofactor biosynthesis protein 1 isoform X4
       101089492 MOCS2; molybdopterin synthase catalytic subunit
       101096816 GPHN; gephyrin isoform X2
       101098093 MOCOS; molybdenum cofactor sulfurase isoform X1
K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K01930 FPGS; folylpolyglutamate synthase [EC:6.3.2.17]
K01307 GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
K00072 SPR; sepiapterin reductase [EC:1.1.1.153]
K00011 AKR1B; aldehyde reductase [EC:1.1.1.21]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00357 QDPR; dihydropteridine reductase [EC:1.5.1.34]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K00502 TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
K20967 MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC:4.1.99.22 4.6.1.17]
K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
K15376 GPHN; gephyrin [EC:2.10.1.1 2.7.7.75]
K15631 ABA3; molybdenum cofactor sulfurtransferase [EC:2.8.1.9]
     00670 One carbon pool by folate [PATH:fca00670]
       101087964 DHFR; dihydrofolate reductase isoform X1
       101082751 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X4
       101086816 MTHFD1; C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
       101083836 MTHFD2; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
       101093354 MTHFD2L; probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 isoform X1
       101091290 SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1
       101086266 SHMT1; serine hydroxymethyltransferase, cytosolic
       101087772 GART; trifunctional purine biosynthetic protein adenosine-3
       101081485 ATIC; bifunctional purine biosynthesis protein ATIC
       101080907 FTCD; formimidoyltransferase-cyclodeaminase isoform X1
       101085804 MTFMT; methionyl-tRNA formyltransferase, mitochondrial
       101084781 AMT; aminomethyltransferase, mitochondrial
       101101166 MTR; methionine synthase isoform X3
       101091231 TYMS; thymidylate synthase
       101091432 ALDH1L1; cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X1
       101088592 ALDH1L2; mitochondrial 10-formyltetrahydrofolate dehydrogenase
       101100576 MTHFR; methylenetetrahydrofolate reductase isoform X2
       101093689 5-formyltetrahydrofolate cyclo-ligase isoform X1
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K13402 MTHFD1L; monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3]
K00288 MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
K13403 MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
K13403 MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K13990 FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K00289 ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K00289 ALDH1L; formyltetrahydrofolate dehydrogenase [EC:1.5.1.6]
K25004 MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
     00830 Retinol metabolism [PATH:fca00830]
     00860 Porphyrin metabolism [PATH:fca00860]
     00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:fca00130]
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:fca01521]
     01524 Platinum drug resistance [PATH:fca01524]
     01523 Antifolate resistance [PATH:fca01523]
       101084221 FOLR1; folate receptor alpha
       101084733 folate receptor gamma-like
       101095853 FOLR2; folate receptor beta
       101086247 SLC19A1; reduced folate transporter isoform X3
       101100096 SLC46A1; proton-coupled folate transporter
       101092966 FPGS; folylpolyglutamate synthase, mitochondrial isoform X2
       101100943 GGH; gamma-glutamyl hydrolase
       101091231 TYMS; thymidylate synthase
       101087964 DHFR; dihydrofolate reductase isoform X1
       101091290 SHMT2; serine hydroxymethyltransferase, mitochondrial isoform X1
       101086266 SHMT1; serine hydroxymethyltransferase, cytosolic
       101100576 MTHFR; methylenetetrahydrofolate reductase isoform X2
       101094304 polyunsaturated fatty acid lipoxygenase ALOX12 isoform X2
       101087772 GART; trifunctional purine biosynthetic protein adenosine-3
       101081485 ATIC; bifunctional purine biosynthesis protein ATIC
       101095617 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
       101086544 IKBKG; NF-kappa-B essential modulator isoform X1
       100142683 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       101096604 RELA; transcription factor p65
       493755 TNF; tumor necrosis factor precursor
       768274 IL1B; interleukin-1 beta
       493687 IL6; interleukin-6 precursor
       101101279 ABCC1; multidrug resistance-associated protein 1 isoform X3
       101085924 ABCC2; ATP-binding cassette sub-family C member 2 isoform X1
       101098502 ABCC3; LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 3
       101096129 ABCC4; ATP-binding cassette sub-family C member 4 isoform X1
       101090542 ABCC5; multidrug resistance-associated protein 5 isoform X2
       101094017 ABCG2; broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K14609 SLC19A1; solute carrier family 19 (folate transporter), member 1
K14613 SLC46A1; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
K01930 FPGS; folylpolyglutamate synthase [EC:6.3.2.17]
K01307 GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
K00560 thyA; thymidylate synthase [EC:2.1.1.45]
K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
K25004 MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.53]
K00458 ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K05667 ABCC3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K05668 ABCC5; ATP-binding cassette, subfamily C (CFTR/MRP), member 5
K05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2
     01522 Endocrine resistance [PATH:fca01522]
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

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Last updated: April 24, 2024