KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
     00230 Purine metabolism [PATH:hsa00230]
       53343 NUDT9; nudix hydrolase 9
       56985 ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
       11164 NUDT5; nudix hydrolase 5
       5236 PGM1; phosphoglucomutase 1
       55276 PGM2; phosphoglucomutase 2
       221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1 like 1
       5634 PRPS2; phosphoribosyl pyrophosphate synthetase 2
       5631 PRPS1; phosphoribosyl pyrophosphate synthetase 1
       5471 PPAT; phosphoribosyl pyrophosphate amidotransferase
       2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
       5198 PFAS; phosphoribosylformylglycinamidine synthase
       10606 PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
       158 ADSL; adenylosuccinate lyase
       471 ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
       353 APRT; adenine phosphoribosyltransferase
       22978 NT5C2; 5'-nucleotidase, cytosolic II
       84618 NT5C1A; 5'-nucleotidase, cytosolic IA
       93034 NT5C1B; 5'-nucleotidase, cytosolic IB
       30833 NT5C; 5', 3'-nucleotidase, cytosolic
       56953 NT5M; 5',3'-nucleotidase, mitochondrial
       100526794 NT5C1B-RDH14; NT5C1B-RDH14 readthrough
       284958 NT5DC4; 5'-nucleotidase domain containing 4
       4907 NT5E; 5'-nucleotidase ecto
       4860 PNP; purine nucleoside phosphorylase
       144811 LACC1; laccase domain containing 1
       3251 HPRT1; hypoxanthine phosphoribosyltransferase 1
       3614 IMPDH1; inosine monophosphate dehydrogenase 1
       3615 IMPDH2; inosine monophosphate dehydrogenase 2
       10201 NME6; NME/NM23 nucleoside diphosphate kinase 6
       29922 NME7; NME/NM23 family member 7
       4831 NME2; NME/NM23 nucleoside diphosphate kinase 2
       4833 NME4; NME/NM23 nucleoside diphosphate kinase 4
       4830 NME1; NME/NM23 nucleoside diphosphate kinase 1
       4832 NME3; NME/NM23 nucleoside diphosphate kinase 3
       654364 NME1-NME2; NME1-NME2 readthrough
       221264 AK9; adenylate kinase 9
       956 ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3
       377841 ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8
       953 ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1
       124583 CANT1; calcium activated nucleotidase 1
       9583 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4
       957 ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
       955 ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6
       131870 NUDT16; nudix hydrolase 16
       3704 ITPA; inosine triphosphatase
       7498 XDH; xanthine dehydrogenase
       318 NUDT2; nudix hydrolase 2
       8833 GMPS; guanine monophosphate synthase
       2766 GMPR; guanosine monophosphate reductase
       51292 GMPR2; guanosine monophosphate reductase 2
       9615 GDA; guanine deaminase
       2987 GUK1; guanylate kinase 1
       6240 RRM1; ribonucleotide reductase catalytic subunit M1
       50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       6241 RRM2; ribonucleotide reductase regulatory subunit M2
       51020 HDDC2; HD domain containing 2
       1716 DGUOK; deoxyguanosine kinase
       1633 DCK; deoxycytidine kinase
       374659 HDDC3; HD domain containing 3
       58497 PRUNE1; prune exopolyphosphatase 1
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       55811 ADCY10; adenylate cyclase 10
       2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
       2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
       2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
       2984 GUCY2C; guanylate cyclase 2C
       3000 GUCY2D; guanylate cyclase 2D, retinal
       2986 GUCY2F; guanylate cyclase 2F, retinal
       4881 NPR1; natriuretic peptide receptor 1
       4882 NPR2; natriuretic peptide receptor 2
       5136 PDE1A; phosphodiesterase 1A
       5153 PDE1B; phosphodiesterase 1B
       5137 PDE1C; phosphodiesterase 1C
       5138 PDE2A; phosphodiesterase 2A
       5139 PDE3A; phosphodiesterase 3A
       5140 PDE3B; phosphodiesterase 3B
       8654 PDE5A; phosphodiesterase 5A
       5145 PDE6A; phosphodiesterase 6A
       5158 PDE6B; phosphodiesterase 6B
       5146 PDE6C; phosphodiesterase 6C
       5147 PDE6D; phosphodiesterase 6D
       5148 PDE6G; phosphodiesterase 6G
       5149 PDE6H; phosphodiesterase 6H
       5152 PDE9A; phosphodiesterase 9A
       10846 PDE10A; phosphodiesterase 10A
       50940 PDE11A; phosphodiesterase 11A
       122622 ADSS1; adenylosuccinate synthase 1
       159 ADSS2; adenylosuccinate synthase 2
       271 AMPD2; adenosine monophosphate deaminase 2
       272 AMPD3; adenosine monophosphate deaminase 3
       270 AMPD1; adenosine monophosphate deaminase 1
       132 ADK; adenosine kinase
       100 ADA; adenosine deaminase
       51816 ADA2; adenosine deaminase 2
       122481 AK7; adenylate kinase 7
       205 AK4; adenylate kinase 4
       26289 AK5; adenylate kinase 5
       204 AK2; adenylate kinase 2
       203 AK1; adenylate kinase 1
       158067 AK8; adenylate kinase 8
       102157402 AK6; adenylate kinase 6
       50808 AK3; adenylate kinase 3
       954 ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2
       84284 NTPCR; nucleoside-triphosphatase, cancer-related
       5167 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1
       5169 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3
       5141 PDE4A; phosphodiesterase 4A
       5142 PDE4B; phosphodiesterase 4B
       5143 PDE4C; phosphodiesterase 4C
       5144 PDE4D; phosphodiesterase 4D
       5150 PDE7A; phosphodiesterase 7A
       27115 PDE7B; phosphodiesterase 7B
       8622 PDE8B; phosphodiesterase 8B
       5151 PDE8A; phosphodiesterase 8A
       2272 FHIT; fragile histidine triad diadenosine triphosphatase
       22875 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4
       9060 PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2
       9061 PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1
       646625 URAD; ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
       55821 ALLC; allantoicase
K13988 NUDT9; ADP-ribose diphosphatase [EC:3.6.1.13]
K01517 ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
K13987 NUDT5; ADP-ribose diphosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 2.7.7.96]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K18533 AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K12305 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00364 guaC; GMP reductase [EC:1.7.1.7]
K00364 guaC; GMP reductase [EC:1.7.1.7]
K01487 guaD; guanine deaminase [EC:3.5.4.3]
K00942 gmk; guanylate kinase [EC:2.7.4.8]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K07023 YGK1; 5'-deoxynucleotidase [EC:3.1.3.89]
K00904 DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
K00893 DCK; deoxycitidine/deoxyadenosine/deoxyguanosine kinase [EC:2.7.1.74 2.7.1.76 2.7.1.113]
K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
K01514 PRUNE; exopolyphosphatase [EC:3.6.1.11]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K08718 PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
K13756 PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
K13757 PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13759 PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13760 PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13761 PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K00856 ADK; adenosine kinase [EC:2.7.1.20]
K01488 add; adenosine deaminase [EC:3.5.4.4]
K19572 CECR1; adenosine deaminase CECR1 [EC:3.5.4.4]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K18532 AK6; adenylate kinase [EC:2.7.4.3]
K00944 AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
K01509 ENTPD2; adenosinetriphosphatase [EC:3.6.1.-]
K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K18424 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13485 PRHOXNB; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
K01477 alc; allantoicase [EC:3.5.3.4]
     00240 Pyrimidine metabolism [PATH:hsa00240]
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
     04024 cAMP signaling pathway [PATH:hsa04024]
       7432 VIP; vasoactive intestinal peptide
       1392 CRH; corticotropin releasing hormone
       1081 CGA; glycoprotein hormones, alpha polypeptide
       3972 LHB; luteinizing hormone subunit beta
       170589 GPHA2; glycoprotein hormone subunit alpha 2
       122876 GPHB5; glycoprotein hormone subunit beta 5
       7252 TSHB; thyroid stimulating hormone subunit beta
       5443 POMC; proopiomelanocortin
       2641 GCG; glucagon
       2695 GIP; gastric inhibitory polypeptide
       2488 FSHB; follicle stimulating hormone subunit beta
       4878 NPPA; natriuretic peptide A
       116 ADCYAP1; adenylate cyclase activating polypeptide 1
       153 ADRB1; adrenoceptor beta 1
       154 ADRB2; adrenoceptor beta 2
       1812 DRD1; dopamine receptor D1
       1816 DRD5; dopamine receptor D5
       135 ADORA2A; adenosine A2a receptor
       3360 HTR4; 5-hydroxytryptamine receptor 4
       3362 HTR6; 5-hydroxytryptamine receptor 6
       5732 PTGER2; prostaglandin E receptor 2
       117 ADCYAP1R1; ADCYAP receptor type I
       7434 VIPR2; vasoactive intestinal peptide receptor 2
       1394 CRHR1; corticotropin releasing hormone receptor 1
       1395 CRHR2; corticotropin releasing hormone receptor 2
       3973 LHCGR; luteinizing hormone/choriogonadotropin receptor
       7253 TSHR; thyroid stimulating hormone receptor
       4158 MC2R; melanocortin 2 receptor
       2740 GLP1R; glucagon like peptide 1 receptor
       2696 GIPR; gastric inhibitory polypeptide receptor
       139760 GPR119; G protein-coupled receptor 119
       2492 FSHR; follicle stimulating hormone receptor
       4881 NPR1; natriuretic peptide receptor 1
       2778 GNAS; GNAS complex locus
       1906 EDN1; endothelin 1
       1907 EDN2; endothelin 2
       1908 EDN3; endothelin 3
       6750 SST; somatostatin
       4852 NPY; neuropeptide Y
       51738 GHRL; ghrelin and obestatin prepropeptide
       5020 OXT; oxytocin/neurophysin I prepropeptide
       3350 HTR1A; 5-hydroxytryptamine receptor 1A
       3351 HTR1B; 5-hydroxytryptamine receptor 1B
       3352 HTR1D; 5-hydroxytryptamine receptor 1D
       3354 HTR1E; 5-hydroxytryptamine receptor 1E
       3355 HTR1F; 5-hydroxytryptamine receptor 1F
       1128 CHRM1; cholinergic receptor muscarinic 1
       1129 CHRM2; cholinergic receptor muscarinic 2
       1813 DRD2; dopamine receptor D2
       2550 GABBR1; gamma-aminobutyric acid type B receptor subunit 1
       9568 GABBR2; gamma-aminobutyric acid type B receptor subunit 2
       134 ADORA1; adenosine A1 receptor
       1909 EDNRA; endothelin receptor type A
       4886 NPY1R; neuropeptide Y receptor Y1
       6751 SSTR1; somatostatin receptor 1
       6752 SSTR2; somatostatin receptor 2
       6755 SSTR5; somatostatin receptor 5
       27198 HCAR1; hydroxycarboxylic acid receptor 1
       338442 HCAR2; hydroxycarboxylic acid receptor 2
       8843 HCAR3; hydroxycarboxylic acid receptor 3
       2867 FFAR2; free fatty acid receptor 2
       56670 SUCNR1; succinate receptor 1
       5733 PTGER3; prostaglandin E receptor 3
       5021 OXTR; oxytocin receptor
       2693 GHSR; growth hormone secretagogue receptor
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       55811 ADCY10; adenylate cyclase 10
       1259 CNGA1; cyclic nucleotide gated channel subunit alpha 1
       1260 CNGA2; cyclic nucleotide gated channel subunit alpha 2
       1261 CNGA3; cyclic nucleotide gated channel subunit alpha 3
       1262 CNGA4; cyclic nucleotide gated channel subunit alpha 4
       1258 CNGB1; cyclic nucleotide gated channel subunit beta 1
       54714 CNGB3; cyclic nucleotide gated channel subunit beta 3
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       814 CAMK4; calcium/calmodulin dependent protein kinase IV
       11149 BVES; blood vessel epicardial substance
       64091 POPDC2; popeye domain containing 2
       64208 POPDC3; popeye domain containing 3
       3776 KCNK2; potassium two pore domain channel subfamily K member 2
       610 HCN2; hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
       10021 HCN4; hyperpolarization activated cyclic nucleotide gated potassium channel 4
       10257 ABCC4; ATP binding cassette subfamily C member 4 (PEL blood group)
       10411 RAPGEF3; Rap guanine nucleotide exchange factor 3
       11069 RAPGEF4; Rap guanine nucleotide exchange factor 4
       6237 RRAS; RAS related
       22800 RRAS2; RAS related 2
       5337 PLD1; phospholipase D1
       5338 PLD2; phospholipase D2
       51196 PLCE1; phospholipase C epsilon 1
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       5906 RAP1A; RAP1A, member of RAS oncogene family
       5908 RAP1B; RAP1B, member of RAS oncogene family
       7074 TIAM1; TIAM Rac1 associated GEF 1
       10451 VAV3; vav guanine nucleotide exchange factor 3
       7409 VAV1; vav guanine nucleotide exchange factor 1
       7410 VAV2; vav guanine nucleotide exchange factor 2
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5058 PAK1; p21 (RAC1) activated kinase 1
       64411 ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
       387 RHOA; ras homolog family member A
       4301 AFDN; afadin, adherens junction formation factor
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       84152 PPP1R1B; protein phosphatase 1 regulatory inhibitor subunit 1B
       5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
       5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
       5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
       1385 CREB1; cAMP responsive element binding protein 1
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       9586 CREB5; cAMP responsive element binding protein 5
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       627 BDNF; brain derived neurotrophic factor
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2737 GLI3; GLI family zinc finger 3
       2735 GLI1; GLI family zinc finger 1
       5727 PTCH1; patched 1
       64399 HHIP; hedgehog interacting protein
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       6662 SOX9; SRY-box transcription factor 9
       268 AMH; anti-Mullerian hormone
       5465 PPARA; peroxisome proliferator activated receptor alpha
       8310 ACOX3; acyl-CoA oxidase 3, pristanoyl
       51 ACOX1; acyl-CoA oxidase 1
       4772 NFATC1; nuclear factor of activated T cells 1
       2149 F2R; coagulation factor II thrombin receptor
       572 BAD; BCL2 associated agonist of cell death
       3991 LIPE; lipase E, hormone sensitive type
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       4659 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
       10398 MYL9; myosin light chain 9
       7137 TNNI3; troponin I3, cardiac type
       5350 PLN; phospholamban
       487 ATP2A1; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
       489 ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
       488 ATP2A2; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
       6262 RYR2; ryanodine receptor 2
       2902 GRIN1; glutamate ionotropic receptor NMDA type subunit 1
       2903 GRIN2A; glutamate ionotropic receptor NMDA type subunit 2A
       2904 GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B
       2905 GRIN2C; glutamate ionotropic receptor NMDA type subunit 2C
       2906 GRIN2D; glutamate ionotropic receptor NMDA type subunit 2D
       116443 GRIN3A; glutamate ionotropic receptor NMDA type subunit 3A
       116444 GRIN3B; glutamate ionotropic receptor NMDA type subunit 3B
       2890 GRIA1; glutamate ionotropic receptor AMPA type subunit 1
       2891 GRIA2; glutamate ionotropic receptor AMPA type subunit 2
       2892 GRIA3; glutamate ionotropic receptor AMPA type subunit 3
       2893 GRIA4; glutamate ionotropic receptor AMPA type subunit 4
       1080 CFTR; CF transmembrane conductance regulator
       476 ATP1A1; ATPase Na+/K+ transporting subunit alpha 1
       477 ATP1A2; ATPase Na+/K+ transporting subunit alpha 2
       478 ATP1A3; ATPase Na+/K+ transporting subunit alpha 3
       480 ATP1A4; ATPase Na+/K+ transporting subunit alpha 4
       23439 ATP1B4; ATPase Na+/K+ transporting family member beta 4
       481 ATP1B1; ATPase Na+/K+ transporting subunit beta 1
       482 ATP1B2; ATPase Na+/K+ transporting subunit beta 2
       483 ATP1B3; ATPase Na+/K+ transporting subunit beta 3
       486 FXYD2; FXYD domain containing ion transport regulator 2
       5348 FXYD1; FXYD domain containing ion transport regulator 1
       6548 SLC9A1; solute carrier family 9 member A1
       84876 ORAI1; ORAI calcium release-activated calcium modulator 1
       490 ATP2B1; ATPase plasma membrane Ca2+ transporting 1
       492 ATP2B3; ATPase plasma membrane Ca2+ transporting 3
       493 ATP2B4; ATPase plasma membrane Ca2+ transporting 4
       491 ATP2B2; ATPase plasma membrane Ca2+ transporting 2
       775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
       776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
       778 CACNA1F; calcium voltage-gated channel subunit alpha1 F
       779 CACNA1S; calcium voltage-gated channel subunit alpha1 S
       5139 PDE3A; phosphodiesterase 3A
       5140 PDE3B; phosphodiesterase 3B
       5141 PDE4A; phosphodiesterase 4A
       5142 PDE4B; phosphodiesterase 4B
       5143 PDE4C; phosphodiesterase 4C
       5144 PDE4D; phosphodiesterase 4D
       10846 PDE10A; phosphodiesterase 10A
K05264 VIP; vasoactive intestinal peptide
K05256 CRH; corticotropin-releasing hormone
K08522 CGA; glycoprotein hormones alpha chain
K08521 LHB; lutropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K05251 TSHB; thyrotropin subunit beta
K05228 POMC; proopiomelanocortin
K05259 GCG; glucagon
K05258 GIP; gastric inhibitory polypeptide
K05250 FSHB; follitropin subunit beta
K12334 NPPA; natriuretic peptide A
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04144 DRD1; dopamine receptor D1
K05840 DRD5; dopamine receptor D5
K04266 ADORA2A; adenosine receptor A2a
K04160 HTR4; 5-hydroxytryptamine receptor 4
K04162 HTR6; 5-hydroxytryptamine receptor 6
K04259 PTGER2; prostaglandin E receptor 2
K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
K04590 VIPR2; vasoactive intestinal peptide receptor 2
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
K04249 TSHR; thyrotropin receptor
K04200 MC2R; melanocortin 2 receptor
K04581 GLP1R; glucagon-like peptide 1 receptor
K04580 GIPR; gastric inhibitory polypeptide receptor
K08424 GPR119; glucose-dependent insulinotropic receptor
K04247 FSHR; follicle stimulating hormone receptor
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05237 SST; somatostatin
K05232 NPY; neuropeptide Y
K05254 GHRL; ghrelin
K05243 OXT; oxytocin-neurophysin 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04153 HTR1; 5-hydroxytryptamine receptor 1
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04145 DRD2; dopamine receptor D2
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04265 ADORA1; adenosine receptor A1
K04197 EDNRA; endothelin receptor type A
K04204 NPY1R; neuropeptide Y receptor type 1
K04217 SSTR1; somatostatin receptor 1
K04218 SSTR2; somatostatin receptor 2
K04221 SSTR5; somatostatin receptor 5
K08401 HCAR1; hydroxycarboxylic acid receptor 1
K08402 HCAR2_3; hydroxycarboxylic acid receptor 2/3
K08402 HCAR2_3; hydroxycarboxylic acid receptor 2/3
K04328 FFAR2; free fatty acid receptor 2
K10042 SUCNR1; succinate receptor 1
K04260 PTGER3; prostaglandin E receptor 3
K04229 OXTR; oxytocin receptor
K04284 GHSR; growth hormone secretagogue receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04948 CNGA1; cyclic nucleotide gated channel alpha 1
K04949 CNGA2; cyclic nucleotide gated channel alpha 2
K04950 CNGA3; cyclic nucleotide gated channel alpha 3
K04951 CNGA4; cyclic nucleotide gated channel alpha 4
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K04953 CNGB3; cyclic nucleotide gated channel beta 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K21108 BVES; blood vessel epicardial substance
K26206 POPDC2; popeye domain-containing protein 2
K26207 POPDC3; popeye domain-containing protein 3
K04913 KCNK2; potassium channel subfamily K member 2
K04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2
K04957 HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K08014 RAPGEF3; Rap guanine nucleotide exchange factor 3
K04351 RAPGEF4; Rap guanine nucleotide exchange factor 4
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K12490 ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
K04513 RHOA; Ras homolog gene family, member A
K05702 AF6; afadin
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K15494 PPP1R1B; protein phosphatase 1 regulatory subunit 1B
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04355 BDNF; brain-derived neurotrophic factor
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K06230 GLI3; zinc finger protein GLI3
K16797 GLI1; zinc finger protein GLI1
K06225 PTCH1; patched 1
K06231 HHIP; hedgehog interacting protein
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K18435 SOX9; transcription factor SOX9 (SOX group E)
K04665 AMH; anti-mullerian hormone
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K03914 F2R; coagulation factor II (thrombin) receptor
K02158 BAD; Bcl-2-antagonist of cell death
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A
K12755 MYL9; myosin regulatory light chain 9
K12044 TNNI3; troponin I, cardiac muscle
K05852 PLN; phospholamban
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K04962 RYR2; ryanodine receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K13360 FXYD1; FXYD domain-containing ion transport regulator 1
K05742 SLC9A1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K16056 ORAI1; calcium release-activated calcium channel protein 1
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K05850 ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
     05030 Cocaine addiction [PATH:hsa05030]
     05031 Amphetamine addiction [PATH:hsa05031]
     05032 Morphine addiction [PATH:hsa05032]
       4988 OPRM1; opioid receptor mu 1
       1812 DRD1; dopamine receptor D1
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       140679 SLC32A1; solute carrier family 32 member 1
       3760 KCNJ3; potassium inwardly rectifying channel subfamily J member 3
       3763 KCNJ6; potassium inwardly rectifying channel subfamily J member 6
       3765 KCNJ9; potassium inwardly rectifying channel subfamily J member 9
       3762 KCNJ5; potassium inwardly rectifying channel subfamily J member 5
       773 CACNA1A; calcium voltage-gated channel subunit alpha1 A
       774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
       2554 GABRA1; gamma-aminobutyric acid type A receptor subunit alpha1
       2555 GABRA2; gamma-aminobutyric acid type A receptor subunit alpha2
       2556 GABRA3; gamma-aminobutyric acid type A receptor subunit alpha3
       2557 GABRA4; gamma-aminobutyric acid type A receptor subunit alpha4
       2558 GABRA5; gamma-aminobutyric acid type A receptor subunit alpha5
       2559 GABRA6; gamma-aminobutyric acid type A receptor subunit alpha6
       2560 GABRB1; gamma-aminobutyric acid type A receptor subunit beta1
       2562 GABRB3; gamma-aminobutyric acid type A receptor subunit beta3
       2561 GABRB2; gamma-aminobutyric acid type A receptor subunit beta2
       2565 GABRG1; gamma-aminobutyric acid type A receptor subunit gamma1
       2566 GABRG2; gamma-aminobutyric acid type A receptor subunit gamma2
       2567 GABRG3; gamma-aminobutyric acid type A receptor subunit gamma3
       2563 GABRD; gamma-aminobutyric acid type A receptor subunit delta
       2564 GABRE; gamma-aminobutyric acid type A receptor subunit epsilon
       55879 GABRQ; gamma-aminobutyric acid type A receptor subunit theta
       2568 GABRP; gamma-aminobutyric acid type A receptor subunit pi
       2569 GABRR1; gamma-aminobutyric acid type A receptor subunit rho1
       2570 GABRR2; gamma-aminobutyric acid type A receptor subunit rho2
       200959 GABRR3; gamma-aminobutyric acid type A receptor subunit rho3
       2550 GABBR1; gamma-aminobutyric acid type B receptor subunit 1
       9568 GABBR2; gamma-aminobutyric acid type B receptor subunit 2
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       2775 GNAO1; G protein subunit alpha o1
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       59345 GNB4; G protein subunit beta 4
       10681 GNB5; G protein subunit beta 5
       54331 GNG2; G protein subunit gamma 2
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       94235 GNG8; G protein subunit gamma 8
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       55970 GNG12; G protein subunit gamma 12
       51764 GNG13; G protein subunit gamma 13
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       2778 GNAS; GNAS complex locus
       156 GRK2; G protein-coupled receptor kinase 2
       157 GRK3; G protein-coupled receptor kinase 3
       2868 GRK4; G protein-coupled receptor kinase 4
       2869 GRK5; G protein-coupled receptor kinase 5
       2870 GRK6; G protein-coupled receptor kinase 6
       408 ARRB1; arrestin beta 1
       409 ARRB2; arrestin beta 2
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       5136 PDE1A; phosphodiesterase 1A
       5153 PDE1B; phosphodiesterase 1B
       5137 PDE1C; phosphodiesterase 1C
       5138 PDE2A; phosphodiesterase 2A
       5139 PDE3A; phosphodiesterase 3A
       5140 PDE3B; phosphodiesterase 3B
       5141 PDE4A; phosphodiesterase 4A
       5142 PDE4B; phosphodiesterase 4B
       5143 PDE4C; phosphodiesterase 4C
       5144 PDE4D; phosphodiesterase 4D
       5150 PDE7A; phosphodiesterase 7A
       27115 PDE7B; phosphodiesterase 7B
       8622 PDE8B; phosphodiesterase 8B
       5151 PDE8A; phosphodiesterase 8A
       10846 PDE10A; phosphodiesterase 10A
       50940 PDE11A; phosphodiesterase 11A
       134 ADORA1; adenosine A1 receptor
K04215 OPRM1; mu-type opioid receptor
K04144 DRD1; dopamine receptor D1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K15015 SLC32A; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05186 GABRG; gamma-aminobutyric acid receptor subunit gamma
K05186 GABRG; gamma-aminobutyric acid receptor subunit gamma
K05186 GABRG; gamma-aminobutyric acid receptor subunit gamma
K05184 GABRD; gamma-aminobutyric acid receptor subunit delta
K05185 GABRE; gamma-aminobutyric acid receptor subunit epsilon
K05192 GABRQ; gamma-aminobutyric acid receptor subunit theta
K05189 GABRP; gamma-aminobutyric acid receptor subunit pi
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K04265 ADORA1; adenosine receptor A1
     05033 Nicotine addiction [PATH:hsa05033]
     05034 Alcoholism [PATH:hsa05034]
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 18, 2024