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KO |
 09100 Metabolism
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09101 Carbohydrate metabolism
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 00010 Glycolysis / Gluconeogenesis [PATH:hsa00010]
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00020 Citrate cycle (TCA cycle) [PATH:hsa00020]
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00030 Pentose phosphate pathway [PATH:hsa00030]
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00040 Pentose and glucuronate interconversions [PATH:hsa00040]
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00051 Fructose and mannose metabolism [PATH:hsa00051]
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00052 Galactose metabolism [PATH:hsa00052]
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00053 Ascorbate and aldarate metabolism [PATH:hsa00053]
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00500 Starch and sucrose metabolism [PATH:hsa00500]
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00520 Amino sugar and nucleotide sugar metabolism [PATH:hsa00520]
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00620 Pyruvate metabolism [PATH:hsa00620]
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 84532 ACSS1; acyl-CoA synthetase short chain family member 1
55902 ACSS2; acyl-CoA synthetase short chain family member 2
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
1737 DLAT; dihydrolipoamide S-acetyltransferase
1738 DLD; dihydrolipoamide dehydrogenase
8050 PDHX; pyruvate dehydrogenase complex component X
124 ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide
125 ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
131 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
127 ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide
130 ADH6; alcohol dehydrogenase 6 (class V)
128 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
10327 AKR1A1; aldo-keto reductase family 1 member A1
5315 PKM; pyruvate kinase M1/2
5313 PKLR; pyruvate kinase L/R
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
98 ACYP2; acylphosphatase 2
97 ACYP1; acylphosphatase 1
217 ALDH2; aldehyde dehydrogenase 2 family member
224 ALDH3A2; aldehyde dehydrogenase 3 family member A2
219 ALDH1B1; aldehyde dehydrogenase 1 family member B1
501 ALDH7A1; aldehyde dehydrogenase 7 family member A1
223 ALDH9A1; aldehyde dehydrogenase 9 family member A1
134526 ACOT12; acyl-CoA thioesterase 12
160287 LDHAL6A; lactate dehydrogenase A like 6A
92483 LDHAL6B; lactate dehydrogenase A like 6B
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
197257 LDHD; lactate dehydrogenase D
2739 GLO1; glyoxalase I
3029 HAGH; hydroxyacylglutathione hydrolase
9380 GRHPR; glyoxylate and hydroxypyruvate reductase
4200 ME2; malic enzyme 2
10873 ME3; malic enzyme 3
4199 ME1; malic enzyme 1
5091 PC; pyruvate carboxylase
4190 MDH1; malate dehydrogenase 1
4191 MDH2; malate dehydrogenase 2
2271 FH; fumarate hydratase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
39 ACAT2; acetyl-CoA acetyltransferase 2
38 ACAT1; acetyl-CoA acetyltransferase 1
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K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K13997 PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00002 AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01512 acyP; acylphosphatase [EC:3.6.1.7]
K01512 acyP; acylphosphatase [EC:3.6.1.7]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K01067 E3.1.2.1; acetyl-CoA hydrolase [EC:3.1.2.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00102 LDHD; D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]
K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
K00049 GRHPR; glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]
K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
K00025 MDH1; malate dehydrogenase [EC:1.1.1.37]
K00026 MDH2; malate dehydrogenase [EC:1.1.1.37]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
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00630 Glyoxylate and dicarboxylate metabolism [PATH:hsa00630]
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00640 Propanoate metabolism [PATH:hsa00640]
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84532 ACSS1; acyl-CoA synthetase short chain family member 1
55902 ACSS2; acyl-CoA synthetase short chain family member 2
79611 ACSS3; acyl-CoA synthetase short chain family member 3
593 BCKDHA; branched chain keto acid dehydrogenase E1 subunit alpha
594 BCKDHB; branched chain keto acid dehydrogenase E1 subunit beta
1629 DBT; dihydrolipoamide branched chain transacylase E2
1738 DLD; dihydrolipoamide dehydrogenase
35 ACADS; acyl-CoA dehydrogenase short chain
8310 ACOX3; acyl-CoA oxidase 3, pristanoyl
51 ACOX1; acyl-CoA oxidase 1
3030 HADHA; hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
1962 EHHADH; enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
1892 ECHS1; enoyl-CoA hydratase, short chain 1
26275 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
23417 MLYCD; malonyl-CoA decarboxylase
18 ABAT; 4-aminobutyrate aminotransferase
5095 PCCA; propionyl-CoA carboxylase subunit alpha
5096 PCCB; propionyl-CoA carboxylase subunit beta
55862 ECHDC1; ethylmalonyl-CoA decarboxylase 1
84693 MCEE; methylmalonyl-CoA epimerase
4594 MMUT; methylmalonyl-CoA mutase
8802 SUCLG1; succinate-CoA ligase GDP/ADP-forming subunit alpha
8801 SUCLG2; succinate-CoA ligase GDP-forming subunit beta
8803 SUCLA2; succinate-CoA ligase ADP-forming subunit beta
4329 ALDH6A1; aldehyde dehydrogenase 6 family member A1
160287 LDHAL6A; lactate dehydrogenase A like 6A
92483 LDHAL6B; lactate dehydrogenase A like 6B
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
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K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00248 ACADS; butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K07515 HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K07514 EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07511 ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
K05605 HIBCH; 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K13524 ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
K01965 PCCA; propionyl-CoA carboxylase alpha chain [EC:6.4.1.3]
K01966 PCCB; propionyl-CoA carboxylase beta chain [EC:6.4.1.3 2.1.3.15]
K18426 ECHDC1; ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.-]
K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
K01899 LSC1; succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
K01900 LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
K01900 LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]
K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
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00650 Butanoate metabolism [PATH:hsa00650]
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00660 C5-Branched dibasic acid metabolism
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00562 Inositol phosphate metabolism [PATH:hsa00562]
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09102 Energy metabolism
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09103 Lipid metabolism
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00061 Fatty acid biosynthesis [PATH:hsa00061]
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31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
197322 ACSF3; acyl-CoA synthetase family member 3
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
27349 MCAT; malonyl-CoA-acyl carrier protein transacylase
2194 FASN; fatty acid synthase
54995 OXSM; 3-oxoacyl-ACP synthase, mitochondrial
84869 CBR4; carbonyl reductase 4
7923 HSD17B8; hydroxysteroid 17-beta dehydrogenase 8
109703458 HTD2; hydroxyacyl-thioester dehydratase type 2
51102 MECR; mitochondrial trans-2-enoyl-CoA reductase
55301 OLAH; oleoyl-ACP hydrolase
23305 ACSL6; acyl-CoA synthetase long chain family member 6
2182 ACSL4; acyl-CoA synthetase long chain family member 4
2180 ACSL1; acyl-CoA synthetase long chain family member 1
51703 ACSL5; acyl-CoA synthetase long chain family member 5
2181 ACSL3; acyl-CoA synthetase long chain family member 3
23205 ACSBG1; acyl-CoA synthetase bubblegum family member 1
81616 ACSBG2; acyl-CoA synthetase bubblegum family member 2
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K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K18660 ACSF3; malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
K11539 CBR4; carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit [EC:1.1.1.-]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
K22540 HTD2; 3-hydroxyacyl-thioester dehydratase, animal type [EC:4.2.1.-]
K07512 MECR; mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]
K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
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00062 Fatty acid elongation [PATH:hsa00062]
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00071 Fatty acid degradation [PATH:hsa00071]
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00073 Cutin, suberine and wax biosynthesis
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00100 Steroid biosynthesis [PATH:hsa00100]
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00120 Primary bile acid biosynthesis [PATH:hsa00120]
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00121 Secondary bile acid biosynthesis
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00140 Steroid hormone biosynthesis [PATH:hsa00140]
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00561 Glycerolipid metabolism [PATH:hsa00561]
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00564 Glycerophospholipid metabolism [PATH:hsa00564]
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00565 Ether lipid metabolism [PATH:hsa00565]
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00600 Sphingolipid metabolism [PATH:hsa00600]
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00590 Arachidonic acid metabolism [PATH:hsa00590]
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00591 Linoleic acid metabolism [PATH:hsa00591]
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00592 alpha-Linolenic acid metabolism [PATH:hsa00592]
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01040 Biosynthesis of unsaturated fatty acids [PATH:hsa01040]
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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00940 Phenylpropanoid biosynthesis
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00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
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00941 Flavonoid biosynthesis
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00944 Flavone and flavonol biosynthesis
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00942 Anthocyanin biosynthesis
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00943 Isoflavonoid biosynthesis
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00946 Degradation of flavonoids
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00901 Indole alkaloid biosynthesis
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00403 Indole diterpene alkaloid biosynthesis
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00950 Isoquinoline alkaloid biosynthesis
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00960 Tropane, piperidine and pyridine alkaloid biosynthesis
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00996 Biosynthesis of various alkaloids
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00232 Caffeine metabolism [PATH:hsa00232]
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00965 Betalain biosynthesis
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00966 Glucosinolate biosynthesis
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00402 Benzoxazinoid biosynthesis
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00311 Penicillin and cephalosporin biosynthesis
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00332 Carbapenem biosynthesis
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00261 Monobactam biosynthesis
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00331 Clavulanic acid biosynthesis
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00521 Streptomycin biosynthesis
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00524 Neomycin, kanamycin and gentamicin biosynthesis [PATH:hsa00524]
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00525 Acarbose and validamycin biosynthesis
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00401 Novobiocin biosynthesis
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00404 Staurosporine biosynthesis
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00405 Phenazine biosynthesis
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00333 Prodigiosin biosynthesis
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00254 Aflatoxin biosynthesis
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31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
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K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
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00998 Biosynthesis of various antibiotics
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00999 Biosynthesis of various plant secondary metabolites
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00997 Biosynthesis of various other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system
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04010 MAPK signaling pathway [PATH:hsa04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:hsa04012]
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04014 Ras signaling pathway [PATH:hsa04014]
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04015 Rap1 signaling pathway [PATH:hsa04015]
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04310 Wnt signaling pathway [PATH:hsa04310]
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04330 Notch signaling pathway [PATH:hsa04330]
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04340 Hedgehog signaling pathway [PATH:hsa04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:hsa04350]
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04390 Hippo signaling pathway [PATH:hsa04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
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04370 VEGF signaling pathway [PATH:hsa04370]
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04371 Apelin signaling pathway [PATH:hsa04371]
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04630 JAK-STAT signaling pathway [PATH:hsa04630]
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04064 NF-kappa B signaling pathway [PATH:hsa04064]
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04668 TNF signaling pathway [PATH:hsa04668]
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04066 HIF-1 signaling pathway [PATH:hsa04066]
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04068 FoxO signaling pathway [PATH:hsa04068]
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04020 Calcium signaling pathway [PATH:hsa04020]
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04070 Phosphatidylinositol signaling system [PATH:hsa04070]
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04072 Phospholipase D signaling pathway [PATH:hsa04072]
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04071 Sphingolipid signaling pathway [PATH:hsa04071]
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04024 cAMP signaling pathway [PATH:hsa04024]
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04022 cGMP-PKG signaling pathway [PATH:hsa04022]
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04151 PI3K-Akt signaling pathway [PATH:hsa04151]
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04152 AMPK signaling pathway [PATH:hsa04152]
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6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
6794 STK11; serine/threonine kinase 11
51719 CAB39; calcium binding protein 39
81617 CAB39L; calcium binding protein 39 like
92335 STRADA; STE20 related adaptor alpha
55437 STRADB; STE20 related adaptor beta
3952 LEP; leptin
3953 LEPR; leptin receptor
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
148 ADRA1A; adrenoceptor alpha 1A
9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
51094 ADIPOR1; adiponectin receptor 1
79602 ADIPOR2; adiponectin receptor 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5207 PFKFB1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
5208 PFKFB2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
5210 PFKFB4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
2203 FBP1; fructose-bisphosphatase 1
8789 FBP2; fructose-bisphosphatase 2
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5211 PFKL; phosphofructokinase, liver type
3172 HNF4A; hepatocyte nuclear factor 4 alpha
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
200186 CRTC2; CREB regulated transcription coactivator 2
1385 CREB1; cAMP responsive element binding protein 1
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
10891 PPARGC1A; PPARG coactivator 1 alpha
1994 ELAVL1; ELAV like RNA binding protein 1
595 CCND1; cyclin D1
890 CCNA2; cyclin A2
8900 CCNA1; cyclin A1
29904 EEF2K; eukaryotic elongation factor 2 kinase
1938 EEF2; eukaryotic translation elongation factor 2
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
23411 SIRT1; sirtuin 1
6517 SLC2A4; solute carrier family 2 member 4
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
3991 LIPE; lipase E, hormone sensitive type
3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase
6720 SREBF1; sterol regulatory element binding transcription factor 1
2194 FASN; fatty acid synthase
31 ACACA; acetyl-CoA carboxylase alpha
6319 SCD; stearoyl-CoA desaturase
79966 SCD5; stearoyl-CoA desaturase 5
32 ACACB; acetyl-CoA carboxylase beta
23417 MLYCD; malonyl-CoA decarboxylase
1374 CPT1A; carnitine palmitoyltransferase 1A
1375 CPT1B; carnitine palmitoyltransferase 1B
126129 CPT1C; carnitine palmitoyltransferase 1C
1149 CIDEA; cell death inducing DFFA like effector a
5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
23216 TBC1D1; TBC1 domain family member 1
5862 RAB2A; RAB2A, member RAS oncogene family
4218 RAB8A; RAB8A, member RAS oncogene family
10890 RAB10; RAB10, member RAS oncogene family
9230 RAB11B; RAB11B, member RAS oncogene family
51552 RAB14; RAB14, member RAS oncogene family
1080 CFTR; CF transmembrane conductance regulator
948 CD36; CD36 molecule (CD36 blood group)
3479 IGF1; insulin like growth factor 1
3480 IGF1R; insulin like growth factor 1 receptor
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
7249 TSC2; TSC complex subunit 2
7248 TSC1; TSC complex subunit 1
6009 RHEB; Ras homolog, mTORC1 binding
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
84335 AKT1S1; AKT1 substrate 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
5468 PPARG; peroxisome proliferator activated receptor gamma
8408 ULK1; unc-51 like autophagy activating kinase 1
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K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04135 ADRA1A; adrenergic receptor alpha-1A
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K19030 PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K13088 ELAVL1; ELAV-like protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K25893 CIDEA; cell death activator CIDE-A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K18341 TBC1D1; TBC1 domain family member 1
K07877 RAB2A; Ras-related protein Rab-2A
K07901 RAB8A; Ras-related protein Rab-8A
K07903 RAB10; Ras-related protein Rab-10
K07905 RAB11B; Ras-related protein Rab-11B
K07881 RAB14; Ras-related protein Rab-14
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K06259 CD36; CD36 antigen
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
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04150 mTOR signaling pathway [PATH:hsa04150]
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04075 Plant hormone signal transduction
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09133 Signaling molecules and interaction
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09140 Cellular Processes
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09150 Organismal Systems
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09151 Immune system
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09152 Endocrine system
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04911 Insulin secretion [PATH:hsa04911]
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04910 Insulin signaling pathway [PATH:hsa04910]
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3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
8660 IRS2; insulin receptor substrate 2
8471 IRS4; insulin receptor substrate 4
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5506 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
5507 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
5509 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
79660 PPP1R3B; protein phosphatase 1 regulatory subunit 3B
90673 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
89801 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
5260 PHKG1; phosphorylase kinase catalytic subunit gamma 1
5261 PHKG2; phosphorylase kinase catalytic subunit gamma 2
5257 PHKB; phosphorylase kinase regulatory subunit beta
5256 PHKA2; phosphorylase kinase regulatory subunit alpha 2
5255 PHKA1; phosphorylase kinase regulatory subunit alpha 1
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5836 PYGL; glycogen phosphorylase L
5837 PYGM; glycogen phosphorylase, muscle associated
5834 PYGB; glycogen phosphorylase B
5140 PDE3B; phosphodiesterase 3B
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5573 PRKAR1A; protein kinase cAMP-dependent type I regulatory subunit alpha
5576 PRKAR2A; protein kinase cAMP-dependent type II regulatory subunit alpha
5577 PRKAR2B; protein kinase cAMP-dependent type II regulatory subunit beta
5575 PRKAR1B; protein kinase cAMP-dependent type I regulatory subunit beta
3991 LIPE; lipase E, hormone sensitive type
5590 PRKCZ; protein kinase C zeta
5584 PRKCI; protein kinase C iota
6517 SLC2A4; solute carrier family 2 member 4
2319 FLOT2; flotillin 2
10211 FLOT1; flotillin 1
10603 SH2B2; SH2B adaptor protein 2
10580 SORBS1; sorbin and SH3 domain containing 1
867 CBL; Cbl proto-oncogene
868 CBLB; Cbl proto-oncogene B
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
23433 RHOQ; ras homolog family member Q
23265 EXOC7; exocyst complex component 7
9322 TRIP10; thyroid hormone receptor interactor 10
6720 SREBF1; sterol regulatory element binding transcription factor 1
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
2194 FASN; fatty acid synthase
5313 PKLR; pyruvate kinase L/R
3101 HK3; hexokinase 3
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
80201 HKDC1; hexokinase domain containing 1
2645 GCK; glucokinase
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
2308 FOXO1; forkhead box O1
10891 PPARGC1A; PPARG coactivator 1 alpha
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
2203 FBP1; fructose-bisphosphatase 1
8789 FBP2; fructose-bisphosphatase 2
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
2475 MTOR; mechanistic target of rapamycin kinase
57521 RPTOR; regulatory associated protein of MTOR complex 1
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6194 RPS6; ribosomal protein S6
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
1977 EIF4E; eukaryotic translation initiation factor 4E
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
6009 RHEB; Ras homolog, mTORC1 binding
572 BAD; BCL2 associated agonist of cell death
6464 SHC1; SHC adaptor protein 1
25759 SHC2; SHC adaptor protein 2
53358 SHC3; SHC adaptor protein 3
399694 SHC4; SHC adaptor protein 4
2885 GRB2; growth factor receptor bound protein 2
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
3265 HRAS; HRas proto-oncogene, GTPase
3845 KRAS; KRAS proto-oncogene, GTPase
4893 NRAS; NRAS proto-oncogene, GTPase
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
8569 MKNK1; MAPK interacting serine/threonine kinase 1
2872 MKNK2; MAPK interacting serine/threonine kinase 2
2002 ELK1; ETS transcription factor ELK1
8651 SOCS1; suppressor of cytokine signaling 1
8835 SOCS2; suppressor of cytokine signaling 2
9021 SOCS3; suppressor of cytokine signaling 3
122809 SOCS4; suppressor of cytokine signaling 4
5770 PTPN1; protein tyrosine phosphatase non-receptor type 1
5792 PTPRF; protein tyrosine phosphatase receptor type F
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3636 INPPL1; inositol polyphosphate phosphatase like 1
3632 INPP5A; inositol polyphosphate-5-phosphatase A
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K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K17453 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07192 FLOT; flotillin
K07193 SH2B; SH2B adapter protein 2
K06086 SORBS1; sorbin and SH3 domain containing protein 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K07194 RHOQ; Ras homolog gene family, member Q
K07195 EXOC7; exocyst complex component 7
K07196 TRIP10; thyroid hormone receptor interactor 10
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; Bcl-2-antagonist of cell death
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04375 ELK1; ETS domain-containing protein Elk-1
K04694 SOCS1; suppressor of cytokine signaling 1
K04695 SOCS2; suppressor of cytokine signaling 2
K04696 SOCS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
|
04922 Glucagon signaling pathway [PATH:hsa04922]
|
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
5140 PDE3B; phosphodiesterase 3B
2641 GCG; glucagon
2642 GCGR; glucagon receptor
2778 GNAS; GNAS complex locus
108 ADCY2; adenylate cyclase 2
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
1385 CREB1; cAMP responsive element binding protein 1
1386 ATF2; activating transcription factor 2
468 ATF4; activating transcription factor 4
10488 CREB3; cAMP responsive element binding protein 3
90993 CREB3L1; cAMP responsive element binding protein 3 like 1
64764 CREB3L2; cAMP responsive element binding protein 3 like 2
84699 CREB3L3; cAMP responsive element binding protein 3 like 3
148327 CREB3L4; cAMP responsive element binding protein 3 like 4
9586 CREB5; cAMP responsive element binding protein 5
55671 PPP4R3A; protein phosphatase 4 regulatory subunit 3A
57223 PPP4R3B; protein phosphatase 4 regulatory subunit 3B
139420 PPP4R3C; protein phosphatase 4 regulatory subunit 3C
5531 PPP4C; protein phosphatase 4 catalytic subunit
200186 CRTC2; CREB regulated transcription coactivator 2
23235 SIK2; salt inducible kinase 2
1387 CREBBP; CREB binding protein
2033 EP300; E1A binding protein p300
10891 PPARGC1A; PPARG coactivator 1 alpha
102724428 SIK; salt inducible kinase 1B (putative)
150094 SIK1; salt inducible kinase 1
2776 GNAQ; G protein subunit alpha q
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
2308 FOXO1; forkhead box O1
23411 SIRT1; sirtuin 1
5465 PPARA; peroxisome proliferator activated receptor alpha
3276 PRMT1; protein arginine methyltransferase 1
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
1374 CPT1A; carnitine palmitoyltransferase 1A
1375 CPT1B; carnitine palmitoyltransferase 1B
126129 CPT1C; carnitine palmitoyltransferase 1C
2998 GYS2; glycogen synthase 2
2997 GYS1; glycogen synthase 1
5257 PHKB; phosphorylase kinase regulatory subunit beta
5256 PHKA2; phosphorylase kinase regulatory subunit alpha 2
5255 PHKA1; phosphorylase kinase regulatory subunit alpha 1
5260 PHKG1; phosphorylase kinase catalytic subunit gamma 1
5261 PHKG2; phosphorylase kinase catalytic subunit gamma 2
810 CALML3; calmodulin like 3
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
801 CALM1; calmodulin 1
163688 CALML6; calmodulin like 6
51806 CALML5; calmodulin like 5
91860 CALML4; calmodulin like 4
5836 PYGL; glycogen phosphorylase L
5837 PYGM; glycogen phosphorylase, muscle associated
5834 PYGB; glycogen phosphorylase B
5207 PFKFB1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
6513 SLC2A1; solute carrier family 2 member 1
6514 SLC2A2; solute carrier family 2 member 2
2645 GCK; glucokinase
2203 FBP1; fructose-bisphosphatase 1
8789 FBP2; fructose-bisphosphatase 2
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5211 PFKL; phosphofructokinase, liver type
5223 PGAM1; phosphoglycerate mutase 1
5224 PGAM2; phosphoglycerate mutase 2
441531 PGAM4; phosphoglycerate mutase family member 4
5315 PKM; pyruvate kinase M1/2
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
160287 LDHAL6A; lactate dehydrogenase A like 6A
92483 LDHAL6B; lactate dehydrogenase A like 6B
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
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K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K05259 GCG; glucagon
K04583 GCGR; glucagon receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K19008 SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K07201 FOXO1; forkhead box protein O1
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
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04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
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04920 Adipocytokine signaling pathway [PATH:hsa04920]
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03320 PPAR signaling pathway [PATH:hsa03320]
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04929 GnRH secretion [PATH:hsa04929]
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04912 GnRH signaling pathway [PATH:hsa04912]
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04913 Ovarian steroidogenesis [PATH:hsa04913]
|
04915 Estrogen signaling pathway [PATH:hsa04915]
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04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
|
04917 Prolactin signaling pathway [PATH:hsa04917]
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04921 Oxytocin signaling pathway [PATH:hsa04921]
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04926 Relaxin signaling pathway [PATH:hsa04926]
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04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
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04918 Thyroid hormone synthesis [PATH:hsa04918]
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04919 Thyroid hormone signaling pathway [PATH:hsa04919]
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04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
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04916 Melanogenesis [PATH:hsa04916]
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04924 Renin secretion [PATH:hsa04924]
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04614 Renin-angiotensin system [PATH:hsa04614]
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04925 Aldosterone synthesis and secretion [PATH:hsa04925]
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04927 Cortisol synthesis and secretion [PATH:hsa04927]
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
|
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09157 Sensory system
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09158 Development and regeneration
|
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09149 Aging
|
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09159 Environmental adaptation
|
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09160 Human Diseases
|
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09161 Cancer: overview
|
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09162 Cancer: specific types
|
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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04930 Type II diabetes mellitus [PATH:hsa04930]
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04940 Type I diabetes mellitus [PATH:hsa04940]
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04950 Maturity onset diabetes of the young [PATH:hsa04950]
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04936 Alcoholic liver disease [PATH:hsa04936]
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712 C1QA; complement C1q A chain
713 C1QB; complement C1q B chain
714 C1QC; complement C1q C chain
717 C2; complement C2
720 C4A; complement C4A (Chido/Rodgers blood group)
721 C4B; complement C4B (Chido/Rodgers blood group)
718 C3; complement C3
719 C3AR1; complement C3a receptor 1
727 C5; complement C5
728 C5AR1; complement C5a receptor 1
3929 LBP; lipopolysaccharide binding protein
929 CD14; CD14 molecule
23643 LY96; lymphocyte antigen 96
7099 TLR4; toll like receptor 4
114609 TIRAP; TIR domain containing adaptor protein
4615 MYD88; MYD88 innate immune signal transduction adaptor
51135 IRAK4; interleukin 1 receptor associated kinase 4
3654 IRAK1; interleukin 1 receptor associated kinase 1
7189 TRAF6; TNF receptor associated factor 6
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
5970 RELA; RELA proto-oncogene, NF-kB subunit
4790 NFKB1; nuclear factor kappa B subunit 1
7124 TNF; tumor necrosis factor
3553 IL1B; interleukin 1 beta
3569 IL6; interleukin 6
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3576 CXCL8; C-X-C motif chemokine ligand 8
148022 TICAM1; TIR domain containing adaptor molecule 1
7187 TRAF3; TNF receptor associated factor 3
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
29110 TBK1; TANK binding kinase 1
3661 IRF3; interferon regulatory factor 3
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3605 IL17A; interleukin 17A
23765 IL17RA; interleukin 17 receptor A
84818 IL17RC; interleukin 17 receptor C
2919 CXCL1; C-X-C motif chemokine ligand 1
2920 CXCL2; C-X-C motif chemokine ligand 2
2921 CXCL3; C-X-C motif chemokine ligand 3
356 FASLG; Fas ligand
355 FAS; Fas cell surface death receptor
8772 FADD; Fas associated via death domain
7132 TNFRSF1A; TNF receptor superfamily member 1A
8717 TRADD; TNFRSF1A associated via death domain
841 CASP8; caspase 8
836 CASP3; caspase 3
8737 RIPK1; receptor interacting serine/threonine kinase 1
257397 TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3
6720 SREBF1; sterol regulatory element binding transcription factor 1
2194 FASN; fatty acid synthase
31 ACACA; acetyl-CoA carboxylase alpha
6319 SCD; stearoyl-CoA desaturase
79966 SCD5; stearoyl-CoA desaturase 5
23175 LPIN1; lipin 1
64900 LPIN3; lipin 3
9663 LPIN2; lipin 2
406999 MIR217; microRNA 217
23411 SIRT1; sirtuin 1
29896 TRA2A; transformer 2 alpha homolog
6434 TRA2B; transformer 2 beta homolog
9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
51094 ADIPOR1; adiponectin receptor 1
79602 ADIPOR2; adiponectin receptor 2
10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
2308 FOXO1; forkhead box O1
2309 FOXO3; forkhead box O3
10891 PPARGC1A; PPARG coactivator 1 alpha
5465 PPARA; peroxisome proliferator activated receptor alpha
1374 CPT1A; carnitine palmitoyltransferase 1A
37 ACADVL; acyl-CoA dehydrogenase very long chain
34 ACADM; acyl-CoA dehydrogenase medium chain
8310 ACOX3; acyl-CoA oxidase 3, pristanoyl
51 ACOX1; acyl-CoA oxidase 1
2168 FABP1; fatty acid binding protein 1
124 ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide
125 ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
131 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
127 ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide
128 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
130 ADH6; alcohol dehydrogenase 6 (class V)
217 ALDH2; aldehyde dehydrogenase 2 family member
224 ALDH3A2; aldehyde dehydrogenase 3 family member A2
219 ALDH1B1; aldehyde dehydrogenase 1 family member B1
501 ALDH7A1; aldehyde dehydrogenase 7 family member A1
223 ALDH9A1; aldehyde dehydrogenase 9 family member A1
1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
32 ACACB; acetyl-CoA carboxylase beta
23417 MLYCD; malonyl-CoA decarboxylase
1375 CPT1B; carnitine palmitoyltransferase 1B
126129 CPT1C; carnitine palmitoyltransferase 1C
50507 NOX4; NADPH oxidase 4
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
2932 GSK3B; glycogen synthase kinase 3 beta
1499 CTNNB1; catenin beta 1
6932 TCF7; transcription factor 7
83439 TCF7L1; transcription factor 7 like 1
6934 TCF7L2; transcription factor 7 like 2
51176 LEF1; lymphoid enhancer binding factor 1
595 CCND1; cyclin D1
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
6416 MAP2K4; mitogen-activated protein kinase kinase 4
5609 MAP2K7; mitogen-activated protein kinase kinase 7
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
9020 MAP3K14; mitogen-activated protein kinase kinase kinase 14
|
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03989 C4; complement component 4
K03990 C3; complement component 3
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03994 C5; complement component 5
K04010 C5AR1; C5a anaphylatoxin chemotactic receptor 1
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96; lymphocyte antigen 96
K10160 TLR4; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8; interleukin 8
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05489 IL17A; interleukin 17A
K05164 IL17RA; interleukin 17 receptor A
K05166 IL17RC; interleukin 17 receptor C
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K12793 MAP3K7IP3; TAK1-binding protein 3
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K17125 MIR217; microRNA 217
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K12897 TRA2; transformer-2 protein
K12897 TRA2; transformer-2 protein
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K09479 ACADVL; very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K08750 FABP1; fatty acid-binding protein 1, liver
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
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04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
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04931 Insulin resistance [PATH:hsa04931]
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04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
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04934 Cushing syndrome [PATH:hsa04934]
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)