| |
KO |
 09100 Metabolism
|
|
|
09120 Genetic Information Processing
|
|
|
09130 Environmental Information Processing
|
|
|
 09140 Cellular Processes
|
|
|
09141 Transport and catabolism
|
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:hsa04110]
|
 04111 Cell cycle - yeast
|
04112 Cell cycle - Caulobacter
|
04113 Meiosis - yeast
|
04114 Oocyte meiosis [PATH:hsa04114]
|
04210 Apoptosis [PATH:hsa04210]
|
04214 Apoptosis - fly
|
04215 Apoptosis - multiple species [PATH:hsa04215]
|
04216 Ferroptosis [PATH:hsa04216]
|
04217 Necroptosis [PATH:hsa04217]
|
04115 p53 signaling pathway [PATH:hsa04115]
|
472 ATM; ATM serine/threonine kinase
11200 CHEK2; checkpoint kinase 2
545 ATR; ATR serine/threonine kinase
1111 CHEK1; checkpoint kinase 1
92344 GORAB; golgin, RAB6 interacting
1029 CDKN2A; cyclin dependent kinase inhibitor 2A
4193 MDM2; MDM2 proto-oncogene
4194 MDM4; MDM4 regulator of p53
7157 TP53; tumor protein p53
10848 PPP1R13L; protein phosphatase 1 regulatory subunit 13 like
1026 CDKN1A; cyclin dependent kinase inhibitor 1A
595 CCND1; cyclin D1
894 CCND2; cyclin D2
896 CCND3; cyclin D3
1019 CDK4; cyclin dependent kinase 4
1021 CDK6; cyclin dependent kinase 6
898 CCNE1; cyclin E1
9134 CCNE2; cyclin E2
1017 CDK2; cyclin dependent kinase 2
2810 SFN; stratifin
56475 RPRM; reprimo, TP53 dependent G2 arrest mediator homolog
891 CCNB1; cyclin B1
9133 CCNB2; cyclin B2
983 CDK1; cyclin dependent kinase 1
1647 GADD45A; growth arrest and DNA damage inducible alpha
4616 GADD45B; growth arrest and DNA damage inducible beta
10912 GADD45G; growth arrest and DNA damage inducible gamma
51512 GTSE1; G2 and S-phase expressed 1
25946 ZNF385A; zinc finger protein 385A
355 FAS; Fas cell surface death receptor
55367 PIDD1; p53-induced death domain protein 1
8797 TNFRSF10A; TNF receptor superfamily member 10a
8795 TNFRSF10B; TNF receptor superfamily member 10b
841 CASP8; caspase 8
637 BID; BH3 interacting domain death agonist
581 BAX; BCL2 associated X, apoptosis regulator
5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
27113 BBC3; BCL2 binding component 3
63970 TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1
10572 SIVA1; SIVA1 apoptosis inducing factor
598 BCL2L1; BCL2 like 1
596 BCL2; BCL2 apoptosis regulator
9540 TP53I3; tumor protein p53 inducible protein 3
9538 EI24; EI24 autophagy associated transmembrane protein
51246 SHISA5; shisa family member 5
64065 PERP; p53 apoptosis effector related to PMP22
64393 ZMAT3; zinc finger matrin-type 3
6477 SIAH1; siah E3 ubiquitin protein ligase 1
54205 CYCS; cytochrome c, somatic
317 APAF1; apoptotic peptidase activating factor 1
842 CASP9; caspase 9
836 CASP3; caspase 3
84883 AIFM2; apoptosis inducing factor mitochondria associated 2
3486 IGFBP3; insulin like growth factor binding protein 3
3479 IGF1; insulin like growth factor 1
5054 SERPINE1; serpin family E member 1
575 ADGRB1; adhesion G protein-coupled receptor B1
3732 CD82; CD82 molecule
7057 THBS1; thrombospondin 1
5268 SERPINB5; serpin family B member 5
1643 DDB2; damage specific DNA binding protein 2
50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
6241 RRM2; ribonucleotide reductase regulatory subunit M2
27244 SESN1; sestrin 1
143686 SESN3; sestrin 3
83667 SESN2; sestrin 2
5728 PTEN; phosphatase and tensin homolog
7249 TSC2; TSC complex subunit 2
55240 STEAP3; STEAP3 metalloreductase
64326 COP1; COP1 E3 ubiquitin ligase
25898 RCHY1; ring finger and CHY zinc finger domain containing 1
900 CCNG1; cyclin G1
901 CCNG2; cyclin G2
8493 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
7161 TP73; tumor protein p73
|
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K27356 PPP1R13L; RelA-associated inhibitor
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K26543 ZNF385A; zinc finger protein 385A
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K13773 TP53AIP1; p53-regulated apoptosis-inducing protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
|
04218 Cellular senescence [PATH:hsa04218]
|
|
|
09144 Cellular community - eukaryotes
|
|
|
09145 Cellular community - prokaryotes
|
|
|
09142 Cell motility
|
|
|
09150 Organismal Systems
|
|
|
09160 Human Diseases
|
|
|
09180 Brite Hierarchies
|
|
|
09190 Not Included in Pathway or Brite
|
KEGG Orthology (KO) - Homo sapiens (human)