KEGG Orthology (KO) - Homo sapiens (human)

[ Brite menu | Organism menu | Download htext ]
    

1st Level  2nd Level  3rd Level  4th Level 

     KO
 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
     05010 Alzheimer's disease [PATH:hsa05010]
     05012 Parkinson's disease [PATH:hsa05012]
       135 ADORA2A; adenosine A2a receptor
       2774 GNAL; G protein subunit alpha L
       1813 DRD2; dopamine receptor D2
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       111 ADCY5; adenylate cyclase 5 
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha 
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta 
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma 
       1812 DRD1; dopamine receptor D1
       7317 UBA1; ubiquitin like modifier activating enzyme 1 
       7318 UBA7; ubiquitin like modifier activating enzyme 7
       7314 UBB; ubiquitin B
       7332 UBE2L3; ubiquitin conjugating enzyme E2 L3 
       9246 UBE2L6; ubiquitin conjugating enzyme E2 L6 
       118424 UBE2J2; ubiquitin conjugating enzyme E2 J2 
       51465 UBE2J1; ubiquitin conjugating enzyme E2 J1 
       7327 UBE2G2; ubiquitin conjugating enzyme E2 G2 
       7326 UBE2G1; ubiquitin conjugating enzyme E2 G1 
       5071 PARK2; parkin RBR E3 ubiquitin protein ligase
       6622 SNCA; synuclein alpha
       2861 GPR37; G protein-coupled receptor 37
       5413 SEPT5; septin 5 
       9627 SNCAIP; synuclein alpha interacting protein
       7345 UCHL1; ubiquitin C-terminal hydrolase L1 
       7054 TH; tyrosine hydroxylase 
       6531 SLC6A3; solute carrier family 6 member 3
       6570 SLC18A1; solute carrier family 18 member A1
       6571 SLC18A2; solute carrier family 18 member A2
       4535 ND1; NADH dehydrogenase, subunit 1 (complex I)
       4536 ND2; MTND2
       4537 ND3; NADH dehydrogenase, subunit 3 (complex I)
       4538 ND4; NADH dehydrogenase, subunit 4 (complex I)
       4539 ND4L; NADH dehydrogenase, subunit 4L (complex I)
       4540 ND5; NADH dehydrogenase, subunit 5 (complex I)
       4541 ND6; NADH dehydrogenase, subunit 6 (complex I)
       4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1 
       4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2 
       4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3 
       4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1 
       4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2 
       4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
       4697 NDUFA4; NDUFA4, mitochondrial complex associated 
       56901 NDUFA4L2; NDUFA4, mitochondrial complex associated like 2
       4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5 
       4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
       4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
       4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8 
       4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9 
       4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10 
       4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
       126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11 
       55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
       51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13 
       4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
       4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2 
       4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
       4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4 
       4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5 
       4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6 
       4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7 
       4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
       4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
       4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10 
       54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
       4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1 
       4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2 
       4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3 
       4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
       4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5 
       4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6 
       374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7 
       4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8 
       4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
       4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
       100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
       6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A 
       6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B 
       6391 SDHC; succinate dehydrogenase complex subunit C
       6392 SDHD; succinate dehydrogenase complex subunit D
       7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 
       4519 CYTB; cytochrome b
       1537 CYC1; cytochrome c1
       7384 UQCRC1; ubiquinol-cytochrome c reductase core protein I 
       7385 UQCRC2; ubiquinol-cytochrome c reductase core protein II 
       7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein 
       440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
       7381 UQCRB; ubiquinol-cytochrome c reductase binding protein 
       27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII 
       29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
       10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
       4514 COX3; cytochrome c oxidase III
       4512 COX1; cytochrome c oxidase subunit I
       4513 COX2; cytochrome c oxidase subunit II
       84701 COX4I2; cytochrome c oxidase subunit 4I2
       1327 COX4I1; cytochrome c oxidase subunit 4I1 
       9377 COX5A; cytochrome c oxidase subunit 5A 
       1329 COX5B; cytochrome c oxidase subunit 5B 
       1337 COX6A1; cytochrome c oxidase subunit 6A1 
       1339 COX6A2; cytochrome c oxidase subunit 6A2 
       1340 COX6B1; cytochrome c oxidase subunit 6B1 
       125965 COX6B2; cytochrome c oxidase subunit 6B2
       1345 COX6C; cytochrome c oxidase subunit 6C 
       1346 COX7A1; cytochrome c oxidase subunit 7A1 
       1347 COX7A2; cytochrome c oxidase subunit 7A2 
       9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
       1349 COX7B; cytochrome c oxidase subunit 7B 
       170712 COX7B2; cytochrome c oxidase subunit 7B2 
       1350 COX7C; cytochrome c oxidase subunit 7C 
       341947 COX8C; cytochrome c oxidase subunit 8C
       1351 COX8A; cytochrome c oxidase subunit 8A 
       498 ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
       506 ATP5B; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 
       509 ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 
       513 ATP5D; ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 
       514 ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 
       4508 ATP6; ATP synthase F0 subunit 6
       515 ATP5F1; ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1
       516 ATP5G1; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9)
       517 ATP5G2; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
       518 ATP5G3; ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9)
       10476 ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex subunit D 
       539 ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 
       522 ATP5J; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6 
       4509 ATP8; ATP synthase F0 subunit 8
       120892 LRRK2; leucine rich repeat kinase 2 
       65018 PINK1; PTEN induced putative kinase 1 
       11315 PARK7; Parkinsonism associated deglycase
       27429 HTRA2; HtrA serine peptidase 2 
       7416 VDAC1; voltage dependent anion channel 1
       7417 VDAC2; voltage dependent anion channel 2
       7419 VDAC3; voltage dependent anion channel 3
       291 SLC25A4; solute carrier family 25 member 4
       292 SLC25A5; solute carrier family 25 member 5
       293 SLC25A6; solute carrier family 25 member 6
       83447 SLC25A31; solute carrier family 25 member 31
       10105 PPIF; peptidylprolyl isomerase F 
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9 
       836 CASP3; caspase 3 
K04266 ADORA2A; adenosine receptor A2a
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K04145 DRD2; dopamine receptor D2
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04144 DRD1; dopamine receptor D1
K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
K10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]
K04551 UBB; ubiquitin B
K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
K04553 UBE2L6; ubiquitin-conjugating enzyme E2 L6 [EC:2.3.2.23]
K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04556 PARK2; parkin [EC:2.3.2.27]
K04528 SNCA; alpha-synuclein
K04243 GPR37; G protein-coupled receptor 37 (endothelin receptor type B-like)
K04557 SEPT5; septin 5
K04558 SNCAIP; synuclein, alpha interacting protein (synphilin)
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K05036 SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K08155 SLC18A1_2; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
K03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3]
K03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3]
K03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3]
K03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3]
K03882 ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3]
K03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3]
K03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
K02132 ATPeF1A; F-type H+-transporting ATPase subunit alpha
K02133 ATPeF1B; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
K02136 ATPeF1G; F-type H+-transporting ATPase subunit gamma
K02134 ATPeF1D; F-type H+-transporting ATPase subunit delta
K02135 ATPeF1E; F-type H+-transporting ATPase subunit epsilon
K02126 ATPeF0A; F-type H+-transporting ATPase subunit a
K02127 ATPeF0B; F-type H+-transporting ATPase subunit b
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02128 ATPeF0C; F-type H+-transporting ATPase subunit c
K02138 ATPeF0D; F-type H+-transporting ATPase subunit d
K02137 ATPeF0O; F-type H+-transporting ATPase subunit O
K02131 ATPeF0F6; F-type H+-transporting ATPase subunit 6
K02125 ATPeF08; F-type H+-transporting ATPase subunit 8
K08844 LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
K05687 PARK7; protein DJ-1
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
     05014 Amyotrophic lateral sclerosis (ALS) [PATH:hsa05014]
     05016 Huntington's disease [PATH:hsa05016]
     05020 Prion diseases [PATH:hsa05020]
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: December 4, 2016