Messenger RNA Biogenesis - Homo sapiens (human)

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     KO 
 Eukaryotic type

   mRNA processing factors

   mRNA surveillance and transport factors

   mRNA degradation factors

     5'-3' decay

     3'-5' decay

       Core exosome factors

       Exosome cofactors

         22894 DIS3; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
         115752 DIS3L; DIS3 like exosome 3'-5' exoribonuclease
         5394 EXOSC10; exosome component 10
         10438 C1D; C1D nuclear receptor corepressor
         10200 MPHOSPH6; M-phase phosphoprotein 6
         55601 DDX60; DExD/H-box helicase 60
         91351 DDX60L; DExD/H-box 60 like

K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-] 
K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
K12592 C1D; exosome complex protein LRP1 
K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] 
K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] 

       TRAMP complex

       Ski complex

       Ccr4-NOT complex

       Pan complex

       Other 3'-5' decay factors

     Other degradation factors

 





 Prokaryotic type













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Last updated: April 9, 2024