Membrane Trafficking - Homo sapiens (human)

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     KO
 Exocytosis
   Calcium ion-dependent exocytosis
   Small GTPases and associated proteins
     Rab GTPases
     Rab associated proteins
       117177 RAB3IP; RAB3A interacting protein
       5866 RAB3IL1; RAB3A interacting protein like 1
       22930 RAB3GAP1; RAB3 GTPase activating protein catalytic subunit 1
       25782 RAB3GAP2; RAB3 GTPase activating non-catalytic protein subunit 2
       22895 RPH3A; rabphilin 3A
       9501 RPH3AL; rabphilin 3A like (without C2 domains)
       87 ACTN1; actinin alpha 1
       81 ACTN4; actinin alpha 4
       89 ACTN3; actinin alpha 3 (gene/pseudogene)
       88 ACTN2; actinin alpha 2
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       6853 SYN1; synapsin I
       6854 SYN2; synapsin II
       8224 SYN3; synapsin III
       54843 SYTL2; synaptotagmin like 2
       84958 SYTL1; synaptotagmin like 1
       94120 SYTL3; synaptotagmin like 3
       94121 SYTL4; synaptotagmin like 4
       94122 SYTL5; synaptotagmin like 5
       6812 STXBP1; syntaxin binding protein 1
       134957 STXBP5; syntaxin binding protein 5
       9515 STXBP5L; syntaxin binding protein 5 like
       9342 SNAP29; synaptosome associated protein 29
       22999 RIMS1; regulating synaptic membrane exocytosis 1
       9699 RIMS2; regulating synaptic membrane exocytosis 2
       5877 RABIF; RAB interacting factor
       2622 GAS8; growth arrest specific 8
       11130 ZWINT; ZW10 interacting kinetochore protein
       4952 OCRL; OCRL, inositol polyphosphate-5-phosphatase
       3633 INPP5B; inositol polyphosphate-5-phosphatase B
       23216 TBC1D1; TBC1 domain family member 1
       9882 TBC1D4; TBC1 domain family member 4
       79774 GRTP1; growth hormone regulated TBC protein 1
       11138 TBC1D8; TBC1 domain family member 8
       54885 TBC1D8B; TBC1 domain family member 8B
       23158 TBC1D9; TBC1 domain family member 9
       23061 TBC1D9B; TBC1 domain family member 9B
       374403 TBC1D10C; TBC1 domain family member 10C
       26000 TBC1D10B; TBC1 domain family member 10B
       83874 TBC1D10A; TBC1 domain family member 10A
       79735 TBC1D17; TBC1 domain family member 17
       10133 OPTN; optineurin
       57553 MICAL3; microtubule associated monooxygenase, calponin and LIM domain containing 3
       64780 MICAL1; microtubule associated monooxygenase, calponin and LIM domain containing 1
       9645 MICAL2; microtubule associated monooxygenase, calponin and LIM domain containing 2
       85377 MICALL1; MICAL like 1
       79778 MICALL2; MICAL like 2
       5830 PEX5; peroxisomal biogenesis factor 5
       51555 PEX5L; peroxisomal biogenesis factor 5 like
       9381 OTOF; otoferlin
       3993 LLGL2; LLGL2, scribble cell polarity complex component
       3996 LLGL1; LLGL1, scribble cell polarity complex component
       5875 RABGGTA; Rab geranylgeranyltransferase alpha subunit
       5876 RABGGTB; Rab geranylgeranyltransferase beta subunit
K16779 RAB3IP; Rab-3A-interacting protein 
K16779 RAB3IP; Rab-3A-interacting protein 
K18270 RAB3GAP1; Rab3 GTPase-activating protein catalytic subunit 
K19937 RAB3GAP2; Rab3 GTPase-activating protein non-catalytic subunit 
K19938 RPH3A; rabphilin-3A 
K19939 RPH3AL; Rab effector Noc2 
K05699 ACTN1_4; actinin alpha 1/4 
K05699 ACTN1_4; actinin alpha 1/4 
K21073 ACTN2_3; actinin alpha 2/3 
K21073 ACTN2_3; actinin alpha 2/3 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K02183 CALM; calmodulin 
K19941 SYN; synapsin 
K19941 SYN; synapsin 
K19941 SYN; synapsin 
K17598 SYTL; synaptotagmin-like protein 
K17598 SYTL; synaptotagmin-like protein 
K17598 SYTL; synaptotagmin-like protein 
K17598 SYTL; synaptotagmin-like protein 
K17598 SYTL; synaptotagmin-like protein 
K15292 STXBP1; syntaxin-binding protein 1 
K08518 STXBP5; syntaxin-binding protein 5 
K08518 STXBP5; syntaxin-binding protein 5 
K08509 SNAP29; synaptosomal-associated protein 29 
K15291 RIMS1; regulating synaptic membrane exocytosis protein 1 
K15297 RIMS2; regulating synaptic membrane exocytosis protein 2 
K19952 RABIF; guanine nucleotide exchange factor 
K19942 GAS8; growth arrest-specific protein 8 
K19943 ZWINT; ZW10 interactor 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K18341 TBC1D1; TBC1 domain family member 1 
K17902 TBC1D4; TBC1 domain family member 4 
K19953 GRTP1; TBC1 domain family member 6 
K19951 TBC1D8_9; TBC1 domain family member 8/9 
K19951 TBC1D8_9; TBC1 domain family member 8/9 
K19951 TBC1D8_9; TBC1 domain family member 8/9 
K19951 TBC1D8_9; TBC1 domain family member 8/9 
K19944 TBC1D10; TBC1 domain family member 10 
K19944 TBC1D10; TBC1 domain family member 10 
K19944 TBC1D10; TBC1 domain family member 10 
K19945 TBC1D17; TBC1 domain family member 17 
K19946 OPTN; optineurin 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19948 MICALL1; MICAL-like protein 1 
K21068 MICALL2; MICAL-like protein 2 
K13342 PEX5; peroxin-5 
K13342 PEX5; peroxin-5 
K19949 OTOF; otoferlin 
K06094 LLGL; lethal(2) giant larvae protein 
K06094 LLGL; lethal(2) giant larvae protein 
K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60] 
K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] 
     Rho GTPases
   Tethering complex
   Others
 
 SNARE
 
 Endocytosis
 
 Endosome - Lysosome transport
 
 Protein recycling
   Rab GTPases and associated proteins
     Rab GTPases
     Rab4 associated proteins
     Rab11 associated proteins
     Others
       8411 EEA1; early endosome antigen 1
       10938 EHD1; EH domain containing 1
       30845 EHD3; EH domain containing 3
       30844 EHD4; EH domain containing 4
       4952 OCRL; OCRL, inositol polyphosphate-5-phosphatase
       3633 INPP5B; inositol polyphosphate-5-phosphatase B
       5147 PDE6D; phosphodiesterase 6D
       387849 REP15; RAB15 effector protein
       57553 MICAL3; microtubule associated monooxygenase, calponin and LIM domain containing 3
       64780 MICAL1; microtubule associated monooxygenase, calponin and LIM domain containing 1
       9645 MICAL2; microtubule associated monooxygenase, calponin and LIM domain containing 2
       85377 MICALL1; MICAL like 1
       79778 MICALL2; MICAL like 2
       10133 OPTN; optineurin
       23216 TBC1D1; TBC1 domain family member 1
       23102 TBC1D2B; TBC1 domain family member 2B
       9882 TBC1D4; TBC1 domain family member 4
       51256 TBC1D7; TBC1 domain family member 7
       107080638 TBC1D7-LOC100130357 readthrough
       27342 RABGEF1; RAB guanine nucleotide exchange factor 1
       5888 RAD51; RAD51 recombinase
       6624 FSCN1; fascin actin-bundling protein 1
       25794 FSCN2; fascin actin-bundling protein 2, retinal
       116983 ACAP3; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
       23527 ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
       9744 ACAP1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
       163486 DENND1B; DENN domain containing 1B
       57706 DENND1A; DENN domain containing 1A
       79958 DENND1C; DENN domain containing 1C
       10260 DENND4A; DENN domain containing 4A
       55667 DENND4C; DENN domain containing 4C
       9909 DENND4B; DENN domain containing 4B
K12478 EEA1; early endosome antigen 1 
K12483 EHD1; EH domain-containing protein 1 
K12476 EHD3; EH domain-containing protein 3 
K12477 EHD4; EH domain-containing protein 4 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36] 
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 
K20243 REP15; Rab15 effector protein 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19947 MICAL; protein-methionine sulfoxide oxidase MICAL [EC:1.14.13.-] 
K19948 MICALL1; MICAL-like protein 1 
K21068 MICALL2; MICAL-like protein 2 
K19946 OPTN; optineurin 
K18341 TBC1D1; TBC1 domain family member 1 
K20166 TBC1D2B; TBC1 domain family member 2B 
K17902 TBC1D4; TBC1 domain family member 4 
K20396 TBC1D7; TBC1 domain family member 7 
K20396 TBC1D7; TBC1 domain family member 7 
K20131 RABGEF1; Rab5 GDP/GTP exchange factor 
K04482 RAD51; DNA repair protein RAD51 
K17455 FSCN1_2; fascin 1/2 
K17455 FSCN1_2; fascin 1/2 
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K12489 ACAP; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 
K20160 DENND1; DENN domain-containing protein 1 
K20160 DENND1; DENN domain-containing protein 1 
K20160 DENND1; DENN domain-containing protein 1 
K20163 DENND4; DENN domain-containing protein 4 
K20163 DENND4; DENN domain-containing protein 4 
K20163 DENND4; DENN domain-containing protein 4 
   Others
 
 Endosome - Golgi transport
 
 Endoplasmic reticulum (ER) - Golgi transport
 
 Others

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Last updated: March 24, 2017