KEGG Orthology (KO)

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 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ko00061]
     00062 Fatty acid elongation [PATH:ko00062]
     00071 Fatty acid degradation [PATH:ko00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
     00073 Cutin, suberine and wax biosynthesis [PATH:ko00073]
     00100 Steroid biosynthesis [PATH:ko00100]
     00120 Primary bile acid biosynthesis [PATH:ko00120]
     00121 Secondary bile acid biosynthesis [PATH:ko00121]
     00140 Steroid hormone biosynthesis [PATH:ko00140]
     00561 Glycerolipid metabolism [PATH:ko00561]
     00564 Glycerophospholipid metabolism [PATH:ko00564]
       K00006  GPD1; glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
       K00057  gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
       K00105  E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]
       K00111  glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
       K00112  glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
       K00113  glpC; glycerol-3-phosphate dehydrogenase subunit C [EC:1.1.5.3]
       K00629  GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
       K13506  GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
       K13507  GAT; glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase [EC:2.3.1.15 2.3.1.42]
       K00630  ATS1; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
       K13508  GPAT; glycerol-3-phosphate acyltransferase [EC:2.3.1.15]
       K00631  plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
       K03621  plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]
       K08591  plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]
       K13509  AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
       K19007  AGPAT5; lysophosphatidiate acyltransferase [EC:2.3.1.51]
       K13513  LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
       K13517  MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
       K13519  LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]
       K13523  AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
       K00655  plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
       K00649  GNPAT; glyceronephosphate O-acyltransferase [EC:2.3.1.42]
       K06123  AYR1; 1-acylglycerone phosphate reductase [EC:1.1.1.101]
       K00980  tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39]
       K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
       K01080  PPAP2; phosphatidate phosphatase [EC:3.1.3.4]
       K15728  LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
       K18693  DPP1; diacylglycerol diphosphate phosphatase / phosphatidate phosphatase [EC:3.1.3.81 3.1.3.4]
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K07029  dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K16368  DGK1; diacylglycerol kinase (CTP) [EC:2.7.1.174]
       K00994  CHPT1, CPT1; diacylglycerol cholinephosphotransferase [EC:2.7.8.2]
       K13644  CEPT1; choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2]
       K01114  plcC; phospholipase C [EC:3.1.4.3]
       K16619  plc, cpa; phospholipase C / alpha-toxin [EC:3.1.4.3]
       K18694  PGC1; phosphatidylglycerol phospholipase C [EC:3.1.4.-]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K16860  PLD3_4; phospholipase D3/4 [EC:3.1.4.4]
       K17717  pld; phospholipase D [EC:3.1.4.4]
       K00650  LCAT; lecithin-cholesterol acyltransferase [EC:2.3.1.43]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1 [EC:3.1.1.32 3.1.1.4]
       K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
       K13512  LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
       K13515  LPCAT3, MBOAT5; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
       K16818  DAD1; phospholipase A1 [EC:3.1.1.32]
       K06128  LYPLA1; lysophospholipase I [EC:3.1.1.5]
       K06129  LYPLA3; lysophospholipase III [EC:3.1.1.5]
       K06130  LYPLA2; lysophospholipase II [EC:3.1.1.5]
       K13333  PLB; lysophospholipase [EC:3.1.1.5]
       K01048  pldB; lysophospholipase [EC:3.1.1.5]
       K14676  NTE, NRE; lysophospholipid hydrolase [EC:3.1.1.5]
       K18695  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]
       K18696  GDE1; glycerophosphodiester phosphodiesterase [EC:3.1.4.46]
       K01126  E3.1.4.46, glpQ, ugpQ; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
       K00623  CHAT; choline O-acetyltransferase [EC:2.3.1.6]
       K01049  ACHE; acetylcholinesterase [EC:3.1.1.7]
       K00866  CKI1; choline kinase [EC:2.7.1.32]
       K14156  CHK; choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82]
       K06124  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75]
       K00968  PCYT1; choline-phosphate cytidylyltransferase [EC:2.7.7.15]
       K00993  EPT1; ethanolaminephosphotransferase [EC:2.7.8.1]
       K05939  aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]
       K00894  ETNK, EKI; ethanolamine kinase [EC:2.7.1.82]
       K00967  PCYT2; ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14]
       K05929  E2.1.1.103, NMT; phosphoethanolamine N-methyltransferase [EC:2.1.1.103]
       K04019  eutA; ethanolamine utilization protein EutA
       K03735  eutB; ethanolamine ammonia-lyase large subunit [EC:4.3.1.7]
       K03736  eutC; ethanolamine ammonia-lyase small subunit [EC:4.3.1.7]
       K14286  AGXT2L1, ETNPPL; ethanolamine-phosphate phospho-lyase [EC:4.2.3.2]
       K00551  PEMT; phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]
       K16369  CHO2; phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17]
       K00550  OPI3; methylene-fatty-acyl-phospholipid synthase [EC:2.1.1.16]
       K00570  pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
       K01521  cdh; CDP-diacylglycerol pyrophosphatase [EC:3.6.1.26]
       K00981  E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]
       K01004  pcs; phosphatidylcholine synthase [EC:2.7.8.24]
       K00998  pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
       K17103  CHO1, pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
       K08729  PTDSS1; phosphatidylserine synthase 1 [EC:2.7.8.-]
       K08730  PTDSS2; phosphatidylserine synthase 2 [EC:2.7.8.29]
       K01613  psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]
       K00995  pgsA, PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
       K01094  GEP4; phosphatidylglycerophosphatase GEP4 [EC:3.1.3.27]
       K01095  pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
       K01096  pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.1.3.81 3.1.3.4 3.6.1.27]
       K18697  pgpC; phosphatidylglycerophosphatase C [EC:3.1.3.27]
       K06131  clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
       K06132  clsC; cardiolipin synthase C [EC:2.7.8.-]
       K08744  CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
       K13511  TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
       K13535  CLD1; cardiolipin-specific phospholipase [EC:3.1.1.-]
       K13514  LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
       K00999  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11]
       K13516  MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
       K13621  BTA1; betaine lipid synthase
       K13622  btaA; S-adenosylmethionine-diacylglycerol 3-amino-3-carboxypropyl transferase
       K13623  btaB; S-adenosylmethionine-diacylgycerolhomoserine-N-methlytransferase
       K00096  araM, egsA; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
       K17104  E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
       K17105  E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
       K19664  carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
       K19665  pssA; archaetidylserine synthase [EC:2.7.8.38]
       K17830  GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
     00565 Ether lipid metabolism [PATH:ko00565]
     00600 Sphingolipid metabolism [PATH:ko00600]
     00590 Arachidonic acid metabolism [PATH:ko00590]
     00591 Linoleic acid metabolism [PATH:ko00591]
     00592 alpha-Linolenic acid metabolism [PATH:ko00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
     01004 Lipid biosynthesis proteins [BR:ko01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
       K11234  MFAL; mating pheromone alpha-factor
       K11235  MFA; mating pheromone A-factor
       K01383  BAR1; barrierpepsin [EC:3.4.23.35]
       K11213  STE2; pheromone alpha factor receptor
       K04627  STE3; pheromone a factor receptor
       K02218  CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]
       K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
       K19860  GPA1; guanine nucleotide-binding protein alpha-1 subunit
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K07973  GNG; guanine nucleotide-binding protein subunit gamma, other
       K19838  SST2; GTPase-activating protein SST2
       K11236  CDC24; cell division control protein 24
       K04393  CDC42; cell division control protein 42
       K19839  RGA1_2; Rho-type GTPase-activating protein 1/2
       K19840  BEM3; Rho-type GTPase-activating protein
       K11237  BEM1; bud emergence protein 1
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K19833  CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
       K11238  BNI1; cytokinesis protein
       K11228  STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
       K19841  STE50; protein STE50
       K11239  STE5; pheromone-response scaffold protein
       K11226  STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K19806  PTP2_3; tyrosine-protein phosphatase 2/3 [EC:3.1.3.48]
       K11240  MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]
       K19812  SDP1; dual-specificity protein phosphatase SDP1 [EC:3.1.3.48]
       K11215  STE12; transcription factor STE12
       K11241  DIG1; down-regulator of invasive growth 1
       K11242  DIG2; down-regulator of invasive growth 2
       K12412  MCM1; pheromone receptor transcription factor
       K11243  FUS1; nuclear fusion protein
       K06652  FAR1; cyclin-dependent kinase inhibitor FAR1
       K12760  CLN1; G1/S-specific cyclin CLN1
       K06650  CLN2; G1/S-specific cyclin CLN2
       K04563  CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
       K11244  WSC; cell wall integrity and stress response component
       K11245  MID2, MTL1; mating pheromone-induced death protein 2
       K19842  ROM1_2; RHO1 GDP-GTP exchange protein 1/2
       K19843  TUS1; Rho1 guanine nucleotide exchange factor TUS1
       K00888  PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K04513  RHOA; Ras homolog gene family, member A
       K19844  BEM2; GTPase-activating protein BEM2
       K19845  SAC7; GTPase-activating protein SAC7
       K17971  BNR1; BNI1-related protein 1
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K11229  BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
       K08294  MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K19846  SPA2; protein SPA2
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K19847  MLP1, KDX1; MPK-like protein 1
       K09265  RLM1; transcription factor RLM1
       K00706  E2.4.1.34; 1,3-beta-glucan synthase [EC:2.4.1.34]
       K15174  PAF1; RNA polymerase II-associated factor 1
       K06649  SWI4; regulatory protein SWI4
       K06648  SWI6; regulatory protein SWI6
       K02555  MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
       K02220  CLB1_2; G2/mitotic-specific cyclin 1/2
       K19848  HKR1; signaling mucin HKR1
       K19849  MSB2; signaling mucin MSB2
       K11246  SHO1; SHO1 osmosensor
       K19850  OPY2; protein OPY2
       K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
       K11232  YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
       K11233  SSK1; osomolarity two-component system, response regulator SSK1
       K11230  SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
       K11227  PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K19704  PTC1; protein phosphatase PTC1 [EC:3.1.3.16]
       K19815  HOT1; high-osmolarity-induced transcription protein 1
       K19807  SMP1; transcription factor SMP1
       K00006  GPD1; glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K09051  SKO1, ATF1, PCR1; ATF/CREB family transcription factor
       K06665  SSN6; glucose repression mediator protein
       K06666  TUP1; glucose repression regulatory protein TUP1
       K17741  GRE2; NADPH-dependent methylglyoxal reductase [EC:1.1.1.283]
       K03085  SIC1; substrate and inhibitor of the cyclin-dependent protein kinase CDC28
       K06651  CLB5_6; S-phase entry cyclin 5/6
       K02515  HSL1; serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
       K02516  PRMT5, HSL7; type II protein arginine methyltransferase [EC:2.1.1.320]
       K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
       K06009  YPS1_2; yapsin 1/2 [EC:3.4.23.41]
       K06630  YWHAE; 14-3-3 protein epsilon
       K19816  MSS11; transcription activator MSS11
       K09448  TEAD; transcriptional enhancer factor
       K19851  FLO11; flocculation protein FLO11
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04341 Hedgehog signaling pathway - Fly [PATH:ko04341]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases

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Last updated: December 8, 2016