KEGG Orthology (KO)

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 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ko00061]
     00062 Fatty acid elongation [PATH:ko00062]
     00071 Fatty acid degradation [PATH:ko00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
     00073 Cutin, suberine and wax biosynthesis [PATH:ko00073]
     00100 Steroid biosynthesis [PATH:ko00100]
     00120 Primary bile acid biosynthesis [PATH:ko00120]
     00121 Secondary bile acid biosynthesis [PATH:ko00121]
     00140 Steroid hormone biosynthesis [PATH:ko00140]
     00561 Glycerolipid metabolism [PATH:ko00561]
     00564 Glycerophospholipid metabolism [PATH:ko00564]
     00565 Ether lipid metabolism [PATH:ko00565]
     00600 Sphingolipid metabolism [PATH:ko00600]
       K00654  E2.3.1.50; serine palmitoyltransferase [EC:2.3.1.50]
       K04708  E1.1.1.102; 3-dehydrosphinganine reductase [EC:1.1.1.102]
       K04709  LAG1; Acyl-CoA-dependent ceramide synthase [EC:2.3.1.24]
       K04710  CERS; ceramide synthetase [EC:2.3.1.24]
       K12348  ASAH1; acid ceramidase [EC:3.5.1.23]
       K12349  ASAH2; neutral ceramidase [EC:3.5.1.23]
       K01441  ACER, ASAH3; alkaline ceramidase [EC:3.5.1.23]
       K04711  YDC1; dihydroceramidase [EC:3.5.1.-]
       K04712  DEGS; sphingolipid delta-4 desaturase [EC:1.14.-.-]
       K04713  SUR2; sphinganine C4-monooxygenase [EC:1.14.13.169]
       K05848  YPC1; phytoceramidase [EC:3.5.1.-]
       K04714  SGMS; shingomyelin synthase [EC:2.7.8.27]
       K12350  SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
       K12351  SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
       K12352  SMPD3; sphingomyelin phosphodiesterase 3 [EC:3.1.4.12]
       K12353  SMPD4; sphingomyelin phosphodiesterase 4 [EC:3.1.4.12]
       K12354  ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase family member 7 [EC:3.1.4.12]
       K01117  E3.1.4.12; sphingomyelin phosphodiesterase [EC:3.1.4.12]
       K01123  E3.1.4.41; sphingomyelin phosphodiesterase D [EC:3.1.4.41]
       K04715  E2.7.1.138, CERK; ceramide kinase [EC:2.7.1.138]
       K01080  PPAP2; phosphatidate phosphatase [EC:3.1.3.4]
       K04716  SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
       K04717  SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K01634  E4.1.2.27; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
       K00720  UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
       K01201  GBA, srfJ; glucosylceramidase [EC:3.2.1.45]
       K17108  GBA2; non-lysosomal glucosylceramidase [EC:3.2.1.45]
       K07553  B4GALT6; beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]
       K01190  lacZ; beta-galactosidase [EC:3.2.1.23]
       K12309  GLB1, ELNR1; beta-galactosidase [EC:3.2.1.23]
       K04628  CGT, UGT8; 2-hydroxyacylsphingosine 1-beta-galactosyltransferase [EC:2.4.1.45]
       K01202  GALC; galactosylceramidase [EC:3.2.1.46]
       K01019  GAL3ST1; galactosylceramide sulfotransferase [EC:2.8.2.11]
       K01130  E3.1.6.1, aslA; arylsulfatase [EC:3.1.6.1]
       K01134  ARSA; arylsulfatase A [EC:3.1.6.8]
       K01186  NEU1; sialidase-1 [EC:3.2.1.18]
       K12357  NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
       K01189  GLA; alpha-galactosidase [EC:3.2.1.22]
       K07406  melA; alpha-galactosidase [EC:3.2.1.22]
       K07407  E3.2.1.22B, galA, rafA; alpha-galactosidase [EC:3.2.1.22]
     00590 Arachidonic acid metabolism [PATH:ko00590]
     00591 Linoleic acid metabolism [PATH:ko00591]
     00592 alpha-Linolenic acid metabolism [PATH:ko00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
     01004 Lipid biosynthesis proteins [BR:ko01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
     01003 Glycosyltransferases [BR:ko01003]
     00510 N-Glycan biosynthesis [PATH:ko00510]
     00513 Various types of N-glycan biosynthesis [PATH:ko00513]
     00512 Mucin type O-glycan biosynthesis [PATH:ko00512]
     00514 Other types of O-glycan biosynthesis [PATH:ko00514]
     00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate [PATH:ko00532]
     00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin [PATH:ko00534]
     00533 Glycosaminoglycan biosynthesis - keratan sulfate [PATH:ko00533]
     00535 Proteoglycans [BR:ko00535]
     00536 Heparan sulfate/heparin binding proteins [BR:ko00536]
     00531 Glycosaminoglycan degradation [PATH:ko00531]
     00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis [PATH:ko00563]
     00601 Glycosphingolipid biosynthesis - lacto and neolacto series [PATH:ko00601]
     00603 Glycosphingolipid biosynthesis - globo series [PATH:ko00603]
     00604 Glycosphingolipid biosynthesis - ganglio series [PATH:ko00604]
     00540 Lipopolysaccharide biosynthesis [PATH:ko00540]
     01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
     00550 Peptidoglycan biosynthesis [PATH:ko00550]
     00511 Other glycan degradation [PATH:ko00511]
       K01186  NEU1; sialidase-1 [EC:3.2.1.18]
       K12357  NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
       K01190  lacZ; beta-galactosidase [EC:3.2.1.23]
       K12111  ebgA; evolved beta-galactosidase subunit alpha [EC:3.2.1.23]
       K12112  ebgC; evolved beta-galactosidase subunit beta
       K12309  GLB1, ELNR1; beta-galactosidase [EC:3.2.1.23]
       K12373  HEXA_B; hexosaminidase [EC:3.2.1.52]
       K14459  HEX; hexosaminidase [EC:3.2.1.52]
       K01191  E3.2.1.24; alpha-mannosidase [EC:3.2.1.24]
       K12311  MAN2B1, LAMAN; lysosomal alpha-mannosidase [EC:3.2.1.24]
       K12312  MAN2B2; epididymis-specific alpha-mannosidase [EC:3.2.1.24]
       K01192  E3.2.1.25, MANBA, manB; beta-mannosidase [EC:3.2.1.25]
       K01227  E3.2.1.96; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96]
       K01206  FUCA; alpha-L-fucosidase [EC:3.2.1.51]
       K15923  AXY8, FUC95A, afcA; alpha-L-fucosidase 2 [EC:3.2.1.51]
       K01444  AGA, aspG; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]
       K01201  GBA, srfJ; glucosylceramidase [EC:3.2.1.45]
       K17108  GBA2; non-lysosomal glucosylceramidase [EC:3.2.1.45]
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
   Transport and catabolism
     04144 Endocytosis [PATH:ko04144]
     04147 Exosome [BR:ko04147]
     04145 Phagosome [PATH:ko04145]
     04142 Lysosome [PATH:ko04142]
       K02154  ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02155  ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
       K03661  ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
       K13289  CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
       K01363  CTSB; cathepsin B [EC:3.4.22.1]
       K01275  CTSC; cathepsin C [EC:3.4.14.1]
       K01379  CTSD; cathepsin D [EC:3.4.23.5]
       K01382  CTSE; cathepsin E [EC:3.4.23.34]
       K01373  CTSF; cathepsin F [EC:3.4.22.41]
       K01319  CTSG; cathepsin G [EC:3.4.21.20]
       K01366  CTSH; cathepsin H [EC:3.4.22.16]
       K09599  CTSP; cathepsin P [EC:3.4.22.-]
       K01371  CTSK; cathepsin K [EC:3.4.22.38]
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K09600  CTSM; cathepsin M [EC:3.4.22.-]
       K01374  CTSO; cathepsin O [EC:3.4.22.42]
       K01368  CTSS; cathepsin S [EC:3.4.22.27]
       K01375  CTSL2, CTSV; cathepsin V [EC:3.4.22.43]
       K08569  CTSW; cathepsin W [EC:3.4.22.-]
       K08568  CTSZ; cathepsin X [EC:3.4.18.1]
       K08565  NAPSA; napsin-A [EC:3.4.23.-]
       K01369  LGMN; legumain [EC:3.4.22.34]
       K01279  TPP1, CLN2; tripeptidyl-peptidase I [EC:3.4.14.9]
       K01189  GLA; alpha-galactosidase [EC:3.2.1.22]
       K12309  GLB1, ELNR1; beta-galactosidase [EC:3.2.1.23]
       K12316  GAA; lysosomal alpha-glucosidase [EC:3.2.1.20]
       K01201  GBA, srfJ; glucosylceramidase [EC:3.2.1.45]
       K01217  IDUA; L-iduronidase [EC:3.2.1.76]
       K01204  NAGA; alpha-N-acetylgalactosaminidase [EC:3.2.1.49]
       K01205  NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50]
       K01202  GALC; galactosylceramidase [EC:3.2.1.46]
       K01195  uidA, GUSB; beta-glucuronidase [EC:3.2.1.31]
       K12373  HEXA_B; hexosaminidase [EC:3.2.1.52]
       K01192  E3.2.1.25, MANBA, manB; beta-mannosidase [EC:3.2.1.25]
       K12311  MAN2B1, LAMAN; lysosomal alpha-mannosidase [EC:3.2.1.24]
       K01186  NEU1; sialidase-1 [EC:3.2.1.18]
       K01134  ARSA; arylsulfatase A [EC:3.1.6.8]
       K01135  ARSB; arylsulfatase B [EC:3.1.6.12]
       K12381  ARSG; arylsulfatase G [EC:3.1.6.-]
       K01132  GALNS; N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]
       K01137  GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]
       K01136  IDS; iduronate 2-sulfatase [EC:3.1.6.13]
       K01565  SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
       K01052  LIPA; lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
       K06129  LYPLA3; lysophospholipase III [EC:3.1.1.5]
       K01158  DNASE2; deoxyribonuclease II [EC:3.1.22.1]
       K12350  SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
       K12348  ASAH1; acid ceramidase [EC:3.5.1.23]
       K01444  AGA, aspG; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]
       K12382  PSAP, SGP1; saposin
       K12383  GM2A; ganglioside GM2 activator
       K01074  PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
       K06528  LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
       K06562  LAMP3; lysosomal-associated membrane protein 3
       K06501  CD68; CD68 antigen
       K06497  CD63, MLA1, TSPAN30; CD63 antigen
       K12384  SCARB2, LIMP2, CD36L2; lysosome membrane protein 2
       K12385  NPC1; Niemann-Pick C1 protein
       K13443  NPC2; Niemann-Pick C2 protein
       K12386  CTNS; cystinosin
       K12301  SLC17A5; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5
       K12347  SLC11A, NRAMP; natural resistance-associated macrophage protein
       K12387  LAPTM; lysosomal-associated transmembrane protein
       K05642  ABCA2; ATP-binding cassette, subfamily A (ABC1), member 2
       K05656  ABCB9, TAPL; ATP-binding cassette, subfamily B (MDR/TAP), member 9
       K06546  CD164, MGC24; CD164 antigen
       K12305  ENTPD4, LALP70; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
       K12388  SORT1; sortilin
       K12389  BTS, CLN3; battenin
       K12390  CLN5; ceroid-lipofuscinosis neuronal protein 5
       K12307  MSFD8, CLN7; MFS transporter, ceroid-lipofuscinosis neuronal protein 7
       K10532  HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78]
       K13444  SUMF1, FGE; sulfatase modifying factor 1
       K08239  GNPTAB; UDP-N-acetylglucosamine-lysosomal-enzyme [EC:2.7.8.17]
       K10087  GNPTG, GNPTAG; N-acetylglucosamine-1-phosphate transferase, gamma subunit
       K01125  NAGPA; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45]
       K06564  IGF2R; insulin-like growth factor 2 receptor
       K10089  M6PR; cation-dependent mannose-6-phosphate receptor
       K04644  CLTA, LCA; clathrin light chain A
       K04645  CLTB, LCB; clathrin light chain B
       K04646  CLTC; clathrin heavy chain
       K12391  AP1G1; AP-1 complex subunit gamma-1
       K12392  AP1B1; AP-1 complex subunit beta-1
       K12393  AP1M; AP-1 complex subunit mu
       K12394  AP1S1_2; AP-1 complex subunit sigma 1/2
       K12395  AP1S3; AP-1 complex subunit sigma-3
       K12396  AP3D1; AP-3 complex subunit delta-1
       K12397  AP3B; AP-3 complex subunit beta
       K12398  AP3M; AP-3 complex subunit mu
       K12399  AP3S; AP-3 complex subunit sigma
       K12400  AP4E1; AP-4 complex subunit epsilon-1
       K12401  AP4B1; AP-4 complex subunit beta-1
       K12402  AP4M1; AP-4 complex subunit mu-1
       K12403  AP4S1; AP-4 complex subunit sigma-1
       K12404  GGA; ADP-ribosylation factor-binding protein GGA
       K04992  MCOLN1; mucolipin 1
     04146 Peroxisome [PATH:ko04146]
     04140 Regulation of autophagy [PATH:ko04140]
 
   Cell motility
 
   Cell growth and death
 
   Cell communication
 
 Organismal Systems
 
 Human Diseases

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Last updated: July 10, 2014