KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
     04613 Neutrophil extracellular trap formation [PATH:ko04613]
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04624 Toll and Imd signaling pathway [PATH:ko04624]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04625 C-type lectin receptor signaling pathway [PATH:ko04625]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04658 Th1 and Th2 cell differentiation [PATH:ko04658]
     04659 Th17 cell differentiation [PATH:ko04659]
     04657 IL-17 signaling pathway [PATH:ko04657]
       K05493  IL17E, IL25; interleukin 17E
       K05164  IL17RA, CD217; interleukin 17 receptor A
       K05165  IL17RB, IL17RH1; interleukin 17 receptor B
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02373  FADD; FAS-associated death domain protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K21124  TRAF3IP2, ACT1; adaptor protein CIKS
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04379  FOS; proto-oncogene protein c-fos
       K09029  FOSB; protein FosB
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04502  FOSL1; fos-like antigen 1
       K05430  IL4; interleukin 4
       K05428  IL5; interleukin 5
       K05435  IL13; interleukin 13
       K21083  CCL17; C-C motif chemokine 17
       K16597  CCL11; C-C motif chemokine 11
       K05489  IL17A, CTLA8; interleukin 17A
       K05494  IL17F, ML1; interleukin 17F
       K05166  IL17RC, IL17RL; interleukin 17 receptor C
       K03174  TRAF3; TNF receptor-associated factor 3
       K03352  APC5, ANAPC5; anaphase-promoting complex subunit 5
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K06855  MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K19603  MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
       K10048  CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
       K09848  TRAF4; TNF receptor-associated factor 4
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K11849  USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
       K09849  TRAF5; TNF receptor-associated factor 5
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K12890  SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10030  IL8, CXCL8; interleukin 8
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K05509  CCL7; C-C motif chemokine 7
       K14625  CCL20; C-C motif chemokine 20
       K05405  IL6; interleukin 6
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K21100  DEFB4; beta-defensin 4
       K13908  MUC5; mucin-5
       K21126  S100A7; protein S100-A7
       K21127  S100A8; protein S100-A8
       K21128  S100A9; protein S100-A9
       K21129  LCN2; lipocalin 2
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K07994  MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
       K05491  IL17C, CX2; interleukin 17C
       K05168  IL17RE; interleukin 17 receptor E
       K04519  IL1B; interleukin 1 beta
       K04687  IFNG; interferon gamma
       K05490  IL17B, CX1; interleukin 17B
       K05492  IL17D, IL27; interleukin 17D
     04662 B cell receptor signaling pathway [PATH:ko04662]
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
 
   09152 Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04922 Glucagon signaling pathway [PATH:ko04922]
     04923 Regulation of lipolysis in adipocytes [PATH:ko04923]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
       K06259  CD36; CD36 antigen
       K08745  SLC27A1_4, FATP1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
       K08746  SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
       K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
       K08749  SLC27A6, FATP6; solute carrier family 27 (fatty acid transporter), member 6
       K08750  FABP1, L-FABP; fatty acid-binding protein 1, liver
       K08751  FABP2; fatty acid-binding protein 2, intestinal
       K08752  FABP3; fatty acid-binding protein 3, muscle and heart
       K08753  FABP4, aP2; fatty acid-binding protein 4, adipocyte
       K08754  FABP5; fatty acid-binding protein 5, epidermal
       K08755  FABP6; fatty acid-binding protein 6, ileal (gastrotropin)
       K08756  FABP7; fatty acid-binding protein 7, brain
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K08525  RXRB, NR2B2; retinoid X receptor beta
       K08526  RXRG, NR2B3; retinoid X receptor gamma
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K01641  HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
       K08757  APOA1; apolipoprotein A-I
       K08758  APOA2; apolipoprotein A-II
       K08759  APOC3; apolipoprotein C-III
       K09025  APOA5; apolipoprotein A-V
       K08761  PLTP; phospholipid transfer protein
       K00029  maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
       K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
       K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
       K00489  CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
       K07431  CYP8B1; sterol 12-alpha-hydroxylase [EC:1.14.14.139]
       K08536  NR1H3, LXRA; liver X receptor alpha
       K00488  CYP27A1; cholestanetriol 26-monooxygenase [EC:1.14.15.15]
       K08762  DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
       K01059  LPL; lipoprotein lipase [EC:3.1.1.34]
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
       K08763  OLR1; oxidised low-density lipoprotein receptor 1
       K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
       K07425  CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
       K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
       K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K10214  ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
       K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
       K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
       K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
       K08766  CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
       K00255  ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
       K00249  ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
       K08767  ANGPTL4, PGAR; angiopoietin-like 4
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing protein 1
       K08768  PLIN1; perilipin-1
       K17284  PLIN2, ADRP; perilipin-2
       K20254  PLIN4; perilipin-4
       K20255  PLIN5; perilipin-5
       K07296  ADIPOQ, ACDC; adiponectin
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K08769  UCP1, SLC25A7; solute carrier family 25 (mitochondrial uncoupling protein), member 7
       K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K08770  UBC; ubiquitin C
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K00864  glpK, GK; glycerol kinase [EC:2.7.1.30]
       K08771  AQP7; aquaporin-7
     04929 GnRH secretion [PATH:ko04929]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04926 Relaxin signaling pathway [PATH:ko04926]
       K21998  RLN1_2; relaxin 1/2
       K04306  RXFP1, LGR7; relaxin family peptide receptor 1
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K16366  EDN1; endothelin-1
       K04198  EDNRB; endothelin receptor type B
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K07994  MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
       K13375  TGFB1; transforming growth factor beta-1
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K12313  ACTA2; actin, aortic smooth muscle
       K06236  COL1A; collagen type I alpha
       K19720  COL3A; collagen type III alpha
       K06237  COL4A; collagen type IV alpha
       K21999  INSL3; insulin-like 3
       K04307  RXFP2, LGR8; relaxin family peptide receptor 2
       K22000  RLN3; relaxin 3
       K08397  RXFP3, RLN3R1; relaxin family peptide receptor 3
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K03099  SOS; son of sevenless
       K04439  ARRB; beta-arrestin
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-bound protein 2
       K22001  INSL5; insulin-like 5
       K08398  RXFP4, RLN3R2; relaxin family peptide receptor 4
       K04637  GNA15; guanine nucleotide-binding protein subunit alpha-15
     04935 Growth hormone synthesis, secretion and action [PATH:ko04935]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:ko04928]
     04916 Melanogenesis [PATH:ko04916]
     04924 Renin secretion [PATH:ko04924]
     04614 Renin-angiotensin system [PATH:ko04614]
     04925 Aldosterone synthesis and secretion [PATH:ko04925]
     04927 Cortisol synthesis and secretion [PATH:ko04927]
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7, TCF-1; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K03068  LRP5_6; low density lipoprotein receptor-related protein 5/6
       K02353  DVL; segment polarity protein dishevelled
       K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
       K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K09821  AGT, SERPINA8; angiotensinogen
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04166  AGTR1; angiotensin II receptor type 1
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K19464  PLEKHG5; pleckstrin homology domain-containing family G member 5
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10031  CXCL12; C-X-C motif chemokine 12
       K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04258  PTGER1; prostaglandin E receptor 1
       K04259  PTGER2; prostaglandin E receptor 2
       K04260  PTGER3; prostaglandin E receptor 3
       K04261  PTGER4; prostaglandin E receptor 4
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06237  COL4A; collagen type IV alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06485  ITGA6, CD49f; integrin alpha 6
       K06487  ITGAV, CD51; integrin alpha V
       K05719  ITGB1, CD29; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator Bcl-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K02158  BAD; Bcl-2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; C-crk adapter molecule crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
       K03898  KNG, BK; kininogen
       K16366  EDN1; endothelin-1
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05430  IL4; interleukin 4
       K05428  IL5; interleukin 5
       K05405  IL6; interleukin 6
       K05431  IL7; interleukin 7
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05435  IL13; interleukin 13
       K05433  IL15; interleukin 15
       K05426  IL23A; interleukin 23 subunit alpha
       K05437  EPO; erythropoietin
       K05414  IFNA; interferon alpha
       K04687  IFNG; interferon gamma
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K05071  IL4R, CD124; interleukin 4 receptor
       K04738  CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
       K05067  IL5RA, CD125; interleukin 5 receptor alpha
       K05055  IL6R, CD126; interleukin 6 receptor
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K05072  IL7R, CD127; interleukin 7 receptor
       K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
       K05074  IL15RA, CD215; interleukin 15 receptor alpha
       K05065  IL23R; interleukin 23 receptor
       K05079  EPOR; erythropoietin receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K15420  EML4; echinoderm microtubule-associated protein-like 4
       K05119  ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K11222  STAT4; signal transducer and activator of transcription 4
       K11225  STAT6; signal transducer and activator of transcription 6
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-bound protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K02678  ETS1, pnt; C-ets-1
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR, MLP1, MLP2; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K08525  RXRB, NR2B2; retinoid X receptor beta
       K08526  RXRG, NR2B3; retinoid X receptor gamma
       K08528  RARB, NR1B2; retinoic acid receptor beta
       K08550  ESR1, NR3A1; estrogen receptor alpha
       K08551  ESR2, NR3A2; estrogen receptor beta
       K09101  NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
       K11256  NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
       K04684  SP1; transcription factor Sp1
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP, PG; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K08527  RARA, NR1B1; retinoic acid receptor alpha
       K06627  CCNA; cyclin-A
       K10054  PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03347  CUL1, CDC53; cullin 1
       K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; G1/S-specific cyclin-E1
       K06618  RB1; retinoblastoma-associated protein
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K10140  DDB2; DNA damage-binding protein 2
       K03511  POLK; DNA polymerase kappa [EC:2.7.7.7]
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K22183  TERC; telomerase RNA component
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K23605  SMAD3; mothers against decapentaplegic homolog 3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
       K04496  CTBP; C-terminal binding protein [EC:1.1.1.428]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; Bcl-2-binding component 3
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K10456  KLHL19, KEAP1, INRF2; kelch-like protein 19
       K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
       K00510  HMOX1; heme oxygenase 1 [EC:1.14.14.18]
       K00355  NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
       K00799  GST, gst; glutathione S-transferase [EC:2.5.1.18]
       K23790  GSTP; glutathione S-transferase P [EC:2.5.1.18]
       K22182  TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  ELOC, TCEB1; elongin-C
       K03873  ELOB, TCEB2; elongin-B
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06052  JAG1, CD339; jagged-1
       K21635  JAG2; jagged-2
       K06051  DLL; delta
       K02599  NOTCH1; Notch 1
       K20994  NOTCH2; Notch 2
       K20995  NOTCH3; Notch 3
       K20996  NOTCH4; Notch 4
       K06054  HES1; hairy and enhancer of split 1
       K06055  HES5; hairy and enhancer of split 5
       K09091  HEY; hairy and enhancer of split related with YRPW motif
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K18806  KIF7; kinesin family member 7
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K21283  BMP2; bone morphogenetic protein 2
       K04662  BMP4; bone morphogenetic protein 4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  AR, NR3C4; androgen receptor
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3, PSA; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancer [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
     05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
     05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
     05203 Viral carcinogenesis [PATH:ko05203]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05225 Hepatocellular carcinoma [PATH:ko05225]
     05226 Gastric cancer [PATH:ko05226]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K04377  MYC; Myc proto-oncogene protein
       K09850  RASSF1; Ras association domain-containing protein 1
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04503  CCND1; G1/S-specific cyclin-D1
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K16857  THBS1; thrombospondin 1
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K19520  UPK3A, UPIII; uroplakin-3a
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04357  EGF; epidermal growth factor
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K00758  deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4]
       K05448  VEGFA; vascular endothelial growth factor A
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K10030  IL8, CXCL8; interleukin 8
       K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05224 Breast cancer [PATH:ko05224]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
     05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05171 Coronavirus disease - COVID-19 [PATH:ko05171]
       K25011  nsp1; SARS coronavirus host translation inhibitor nsp1
       K25012  nsp2; SARS coronavirus non-structural protein 2
       K25013  nsp3; SARS coronavirus non-structural protein 3 [EC:3.4.19.12]
       K25014  nsp4; SARS coronavirus non-structural protein 4
       K25015  nsp5; SARS coronavirus 3C-like proteinase [EC:3.4.22.69]
       K25016  nsp6; SARS coronavirus non-structural protein 6
       K25017  nsp7; SARS coronavirus non-structural protein 7
       K25018  nsp8; SARS coronavirus non-structural protein 8
       K25019  nsp9; SARS coronavirus non-structural protein 9
       K25020  nsp10; SARS coronavirus non-structural protein 10
       K25021  nsp12; Coronaviridae RNA-directed RNA polymerase [EC:2.7.7.48]
       K25022  nsp13; SARS coronavirus helicase [EC:5.6.2.5]
       K25023  nsp14; SARS coronavirus proofreading exoribonuclease [EC:3.1.13.-]
       K25024  nsp15; SARS coronavirus uridylate-specific endoribonuclease
       K25025  nsp16; SARS coronavirus 2'-O-methyltransferase [EC:2.1.1.-]
       K24152  S; SARS coronavirus spike glycoprotein
       K24151  E; SARS coronavirus envelope small membrane protein
       K24150  M; SARS coronavirus membrane protein
       K24106  N; SARS coronavirus nucleocapsid protein
       K24579  3a; SARS coronavirus accessory protein 3a
       K24580  6; SARS coronavirus accessory protein 6
       K24581  7a; SARS coronavirus accessory protein 7a
       K24582  7b; SARS coronavirus accessory protein 7b
       K24583  8; SARS coronavirus accessory protein 8
       K24584  10; SARS coronavirus accessory protein 10
       K09633  TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
       K09708  ACE2, ACEH; angiotensin-converting enzyme 2 [EC:3.4.17.23]
       K06724  NRP1, CD304; neuropilin 1
       K01283  ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
       K04303  MAS1; proto-oncogene Mas
       K04166  AGTR1; angiotensin II receptor type 1
       K21421  NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05405  IL6; interleukin 6
       K04519  IL1B; interleukin 1 beta
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K10030  IL8, CXCL8; interleukin 8
       K06059  ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05055  IL6R, CD126; interleukin 6 receptor
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K05429  IL2; interleukin 2
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K02981  RP-S2e, RPS2; small subunit ribosomal protein S2e
       K02985  RP-S3e, RPS3; small subunit ribosomal protein S3e
       K02984  RP-S3Ae, RPS3A; small subunit ribosomal protein S3Ae
       K02987  RP-S4e, RPS4; small subunit ribosomal protein S4e
       K02989  RP-S5e, RPS5; small subunit ribosomal protein S5e
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K02993  RP-S7e, RPS7; small subunit ribosomal protein S7e
       K02995  RP-S8e, RPS8; small subunit ribosomal protein S8e
       K02997  RP-S9e, RPS9; small subunit ribosomal protein S9e
       K02947  RP-S10e, RPS10; small subunit ribosomal protein S10e
       K02949  RP-S11e, RPS11; small subunit ribosomal protein S11e
       K02951  RP-S12e, RPS12; small subunit ribosomal protein S12e
       K02953  RP-S13e, RPS13; small subunit ribosomal protein S13e
       K02955  RP-S14e, RPS14; small subunit ribosomal protein S14e
       K02958  RP-S15e, RPS15; small subunit ribosomal protein S15e
       K02957  RP-S15Ae, RPS15A; small subunit ribosomal protein S15Ae
       K02960  RP-S16e, RPS16; small subunit ribosomal protein S16e
       K02962  RP-S17e, RPS17; small subunit ribosomal protein S17e
       K02964  RP-S18e, RPS18; small subunit ribosomal protein S18e
       K02966  RP-S19e, RPS19; small subunit ribosomal protein S19e
       K02969  RP-S20e, RPS20; small subunit ribosomal protein S20e
       K02971  RP-S21e, RPS21; small subunit ribosomal protein S21e
       K02973  RP-S23e, RPS23; small subunit ribosomal protein S23e
       K02974  RP-S24e, RPS24; small subunit ribosomal protein S24e
       K02975  RP-S25e, RPS25; small subunit ribosomal protein S25e
       K02976  RP-S26e, RPS26; small subunit ribosomal protein S26e
       K02978  RP-S27e, RPS27; small subunit ribosomal protein S27e
       K02977  RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
       K02979  RP-S28e, RPS28; small subunit ribosomal protein S28e
       K02980  RP-S29e, RPS29; small subunit ribosomal protein S29e
       K02983  RP-S30e, RPS30; small subunit ribosomal protein S30e
       K02998  RP-SAe, RPSA; small subunit ribosomal protein SAe
       K02925  RP-L3e, RPL3; large subunit ribosomal protein L3e
       K02930  RP-L4e, RPL4; large subunit ribosomal protein L4e
       K02932  RP-L5e, RPL5; large subunit ribosomal protein L5e
       K02934  RP-L6e, RPL6; large subunit ribosomal protein L6e
       K02937  RP-L7e, RPL7; large subunit ribosomal protein L7e
       K02936  RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae
       K02938  RP-L8e, RPL8; large subunit ribosomal protein L8e
       K02940  RP-L9e, RPL9; large subunit ribosomal protein L9e
       K02866  RP-L10e, RPL10; large subunit ribosomal protein L10e
       K02865  RP-L10Ae, RPL10A; large subunit ribosomal protein L10Ae
       K02868  RP-L11e, RPL11; large subunit ribosomal protein L11e
       K02870  RP-L12e, RPL12; large subunit ribosomal protein L12e
       K02873  RP-L13e, RPL13; large subunit ribosomal protein L13e
       K02872  RP-L13Ae, RPL13A; large subunit ribosomal protein L13Ae
       K02875  RP-L14e, RPL14; large subunit ribosomal protein L14e
       K02877  RP-L15e, RPL15; large subunit ribosomal protein L15e
       K02880  RP-L17e, RPL17; large subunit ribosomal protein L17e
       K02883  RP-L18e, RPL18; large subunit ribosomal protein L18e
       K02882  RP-L18Ae, RPL18A; large subunit ribosomal protein L18Ae
       K02885  RP-L19e, RPL19; large subunit ribosomal protein L19e
       K02889  RP-L21e, RPL21; large subunit ribosomal protein L21e
       K02891  RP-L22e, RPL22; large subunit ribosomal protein L22e
       K02894  RP-L23e, RPL23; large subunit ribosomal protein L23e
       K02893  RP-L23Ae, RPL23A; large subunit ribosomal protein L23Ae
       K02896  RP-L24e, RPL24; large subunit ribosomal protein L24e
       K02898  RP-L26e, RPL26; large subunit ribosomal protein L26e
       K02901  RP-L27e, RPL27; large subunit ribosomal protein L27e
       K02900  RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae
       K02903  RP-L28e, RPL28; large subunit ribosomal protein L28e
       K02905  RP-L29e, RPL29; large subunit ribosomal protein L29e
       K02908  RP-L30e, RPL30; large subunit ribosomal protein L30e
       K02910  RP-L31e, RPL31; large subunit ribosomal protein L31e
       K02912  RP-L32e, RPL32; large subunit ribosomal protein L32e
       K02915  RP-L34e, RPL34; large subunit ribosomal protein L34e
       K02918  RP-L35e, RPL35; large subunit ribosomal protein L35e
       K02917  RP-L35Ae, RPL35A; large subunit ribosomal protein L35Ae
       K02920  RP-L36e, RPL36; large subunit ribosomal protein L36e
       K02922  RP-L37e, RPL37; large subunit ribosomal protein L37e
       K02921  RP-L37Ae, RPL37A; large subunit ribosomal protein L37Ae
       K02923  RP-L38e, RPL38; large subunit ribosomal protein L38e
       K02924  RP-L39e, RPL39; large subunit ribosomal protein L39e
       K02927  RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
       K02928  RP-L41e, RPL41; large subunit ribosomal protein L41e
       K02929  RP-L44e, RPL44; large subunit ribosomal protein L44e
       K02941  RP-LP0, RPLP0; large subunit ribosomal protein LP0
       K02942  RP-LP1, RPLP1; large subunit ribosomal protein LP1
       K02943  RP-LP2, RPLP2; large subunit ribosomal protein LP2
       K06856  IGH; immunoglobulin heavy chain
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K05404  TLR7; toll-like receptor 7
       K10170  TLR8, CD288; toll-like receptor 8
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K05401  TLR3, CD283; toll-like receptor 3
       K12646  RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
       K12159  ISG15; ubiquitin cross-reactive protein
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K03174  TRAF3; TNF receptor-associated factor 3
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K17834  CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
       K12654  STING1, TMEM173, MITA; stimulator of interferon genes protein
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K12968  ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
       K14216  OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
       K14754  MX; interferon-induced GTP-binding protein Mx
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
       K04009  C3AR1; C3a anaphylatoxin chemotactic receptor
       K03990  C3; complement component 3
       K01335  CFB; complement factor B [EC:3.4.21.47]
       K01334  CFD; complement factor D [EC:3.4.21.46]
       K03994  C5; complement component 5
       K03995  C6; complement component 6
       K03996  C7; complement component 7
       K03997  C8A; complement component 8 subunit alpha
       K03998  C8B; complement component 8 subunit beta
       K03999  C8G; complement component 8 subunit gamma
       K04000  C9; complement component 9
       K06496  SELP, CD62P; selectin, platelet
       K03900  VWF; von Willebrand factor
       K03986  C1QA; complement C1q subcomponent subunit A
       K03987  C1QB; complement C1q subcomponent subunit B
       K03988  C1QG; complement C1q subcomponent subunit C
       K01330  C1R; complement component 1, r subcomponent [EC:3.4.21.41]
       K01331  C1S; complement component 1, s subcomponent [EC:3.4.21.42]
       K01332  C2; complement component 2 [EC:3.4.21.43]
       K03989  C4; complement component 4
       K03991  MBL; mannose-binding lectin
       K03992  MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-]
       K03993  MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104]
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K03917  F13A1; coagulation factor XIII A1 polypeptide [EC:2.3.2.13]
       K03906  F13B; coagulation factor XIII B polypeptide
       K03903  FGA; fibrinogen alpha chain
       K03904  FGB; fibrinogen beta chain
       K03905  FGG; fibrinogen gamma chain
     05164 Influenza A [PATH:ko05164]
     05162 Measles [PATH:ko05162]
     05168 Herpes simplex virus 1 infection [PATH:ko05168]
     05163 Human cytomegalovirus infection [PATH:ko05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05165 Human papillomavirus infection [PATH:ko05165]
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
     05310 Asthma [PATH:ko05310]
     05322 Systemic lupus erythematosus [PATH:ko05322]
     05323 Rheumatoid arthritis [PATH:ko05323]
       K05412  CD80; CD80 antigen
       K05413  CD86; CD86 antigen
       K06470  CD28; CD28 antigen
       K06538  CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
       K06752  MHC2; MHC class II antigen
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K05718  ITGAL, CD11a; integrin alpha L
       K06464  ITGB2, CD18; integrin beta 2
       K06490  ICAM1, CD54; intercellular adhesion molecule 1
       K05433  IL15; interleukin 15
       K05475  TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
       K05476  TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
       K06856  IGH; immunoglobulin heavy chain
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K05417  IL11; interleukin 11
       K05482  IL18, IL1F4; interleukin 18
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K05426  IL23A; interleukin 23 subunit alpha
       K05489  IL17A, CTLA8; interleukin 17A
       K05261  PTH; parathyroid hormone
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
       K02145  ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
       K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
       K02148  ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
       K02149  ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
       K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
       K02151  ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
       K02152  ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
       K02153  ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
       K02154  ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02155  ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
       K03661  ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
       K01371  CTSK; cathepsin K [EC:3.4.22.38]
       K14379  ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K12499  CCL5; C-C motif chemokine 5
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K05408  CCL3; C-C motif chemokine 3
       K14625  CCL20; C-C motif chemokine 20
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10030  IL8, CXCL8; interleukin 8
       K10031  CXCL12; C-X-C motif chemokine 12
       K05448  VEGFA; vascular endothelial growth factor A
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05465  ANGPT1; angiopoietin 1
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K04687  IFNG; interferon gamma
     05320 Autoimmune thyroid disease [PATH:ko05320]
     05321 Inflammatory bowel disease [PATH:ko05321]
     05330 Allograft rejection [PATH:ko05330]
     05332 Graft-versus-host disease [PATH:ko05332]
     05340 Primary immunodeficiency [PATH:ko05340]
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
     05417 Lipid and atherosclerosis [PATH:ko05417]
       K14462  APOB; apolipoprotein B
       K08760  APOA4; apolipoprotein A-IV
       K08757  APOA1; apolipoprotein A-I
       K12473  LDLR; low-density lipoprotein receptor
       K08763  OLR1; oxidised low-density lipoprotein receptor 1
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K04513  RHOA; Ras homolog gene family, member A
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02159  BAX; apoptosis regulator BAX
       K02158  BAD; Bcl-2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator Bcl-2
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K09364  POU2F, OTF; POU domain transcription factor, class 2
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
       K07408  CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
       K17683  CYP2A6; cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
       K17709  CYP2B6; cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
       K17718  CYP2C8; cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
       K19722  AGER, RAGE; receptor for advanced glycosylation end products
       K08008  NOX1, MOX1; NADPH oxidase 1
       K21421  NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
       K08010  NCF2, P67PHOX; neutrophil cytosolic factor 2
       K08012  NCF4, P40PHOX; neutrophil cytosolic factor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K04393  CDC42; cell division control protein 42
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K06490  ICAM1, CD54; intercellular adhesion molecule 1
       K10030  IL8, CXCL8; interleukin 8
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K06494  SELE, CD62E; selectin, endothelial cell
       K06496  SELP, CD62P; selectin, platelet
       K06527  VCAM1, CD106; vascular cell adhesion molecule 1
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K04077  groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
       K03283  HSPA1_6_8; heat shock 70kDa protein 1/6/8
       K26598  HSPA2; heat shock 70kDa protein 2
       K09489  HSPA4; heat shock 70kDa protein 4
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K10159  TLR2, CD282; toll-like receptor 2
       K05399  LBP; lipopolysaccharide-binding protein
       K04391  CD14; monocyte differentiation antigen CD14
       K05400  LY96, MD-2; lymphocyte antigen 96
       K10160  TLR4, CD284; toll-like receptor 4
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05842  TRIF; toll-like receptor adapter molecule 1
       K03174  TRAF3; TNF receptor-associated factor 3
       K10645  MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
       K12650  TANK; TRAF family member-associated NF-kappa-B activator
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K09447  IRF7; interferon regulatory factor 7
       K05411  IRF3; interferon regulatory factor 3
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K06259  CD36; CD36 antigen
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K08525  RXRB, NR2B2; retinoid X receptor beta
       K08526  RXRG, NR2B3; retinoid X receptor gamma
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K05730  VAV; guanine nucleotide exchange factor VAV
       K10169  TLR6, CD286; toll-like receptor 6
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K12499  CCL5; C-C motif chemokine 5
       K05408  CCL3; C-C motif chemokine 3
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K05482  IL18, IL1F4; interleukin 18
       K09490  HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
       K09054  ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K10950  ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K08860  EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K09027  XBP1; X box-binding protein 1
       K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
       K05679  ABCG1; ATP-binding cassette, subfamily G (WHITE), member 1
       K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K20053  VLDLR; very low-density lipoprotein receptor
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04396  CASP6; caspase 6 [EC:3.4.22.59]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K04451  TP53, P53; tumor protein p53
     05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
     05410 Hypertrophic cardiomyopathy [PATH:ko05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
     05414 Dilated cardiomyopathy [PATH:ko05414]
     05415 Diabetic cardiomyopathy [PATH:ko05415]
     05416 Viral myocarditis [PATH:ko05416]
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
     01000 Enzymes [BR:ko01000]
     01001 Protein kinases [BR:ko01001]
     01009 Protein phosphatases and associated proteins [BR:ko01009]
     01002 Peptidases and inhibitors [BR:ko01002]
       K06002  PGA; pepsin A [EC:3.4.23.1]
       K01377  PGC; gastricsin [EC:3.4.23.3]
       K04521  BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
       K07747  BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
       K01378  CYM; chymosin [EC:3.4.23.4]
       K01380  REN; renin [EC:3.4.23.15]
       K01379  CTSD; cathepsin D [EC:3.4.23.5]
       K01382  CTSE; cathepsin E [EC:3.4.23.34]
       K01386  E3.4.23.23; mucorpepsin [EC:3.4.23.23]
       K01383  BAR1; barrierpepsin [EC:3.4.23.35]
       K06004  E3.4.23.18; aspergillopepsin I [EC:3.4.23.18]
       K20737  EAPA; endothiapepsin [EC:3.4.23.22]
       K01381  PEP4; saccharopepsin [EC:3.4.23.25]
       K08245  E3.4.23.40; phytepsin [EC:3.4.23.40]
       K06007  PFAPG; plasmepsin I [EC:3.4.23.38]
       K06008  PFAPD; plasmepsin II [EC:3.4.23.39]
       K06009  YPS1_2; yapsin 1/2 [EC:3.4.23.41]
       K06005  SAP; candidapepsin [EC:3.4.23.24]
       K08565  NAPSA; napsin-A [EC:3.4.23.-]
       K22683  APF2; aspartyl protease family protein [EC:3.4.23.-]
       K22599  PR; HIV protease [EC:3.4.23.16 3.4.23.47]
       K25054  PR; HTLV-1 protease [EC:3.4.23.-]
       K01385  E3.4.23.42; thermopsin [EC:3.4.23.42]
       K03101  lspA; signal peptidase II [EC:3.4.23.36]
       K04505  PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
       K04522  PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
       K09595  HM13; minor histocompatibility antigen H13 [EC:3.4.23.-]
       K09596  SPPL2A; signal peptide peptidase-like 2A [EC:3.4.23.-]
       K09597  SPPL2B; signal peptide peptidase-like 2B [EC:3.4.23.-]
       K14212  SPPL2C, IMP5; signal peptide peptidase-like 2C [EC:3.4.23.-]
       K09598  SPPL3; signal peptide peptidase-like 3 [EC:3.4.23.-]
       K02654  pilD, pppA; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
       K02464  gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]
       K10966  tcpJ; toxin coregulated pilus biosynthesis protein J [EC:3.4.23.43 2.1.1.-]
       K02506  hofD, hopD; leader peptidase HopD [EC:3.4.23.43]
       K02278  cpaA, tadV; prepilin peptidase CpaA [EC:3.4.23.43]
       K07991  flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
       K06012  gpr; spore protease [EC:3.4.24.78]
       K01355  ompT; omptin [EC:3.4.23.49]
       K08566  pla; plasminogen activator [EC:3.4.23.48]
       K08477  pgtE; outer membrane protease E [EC:3.4.21.-]
       K13520  icsP, sopA; outer membrane protease [EC:3.4.23.-]
       K24552  ASPRV1; retroviral-like aspartic protease 1 [EC:3.4.23.-]
       K03605  hyaD, hybD; hydrogenase maturation protease [EC:3.4.23.-]
       K08315  hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]
       K06383  spoIIGA; stage II sporulation protein GA (sporulation sigma-E factor processing peptidase) [EC:3.4.23.-]
       K06000  E3.4.22.2; papain [EC:3.4.22.2]
       K20738  E3.4.22.6; chymopapain [EC:3.4.22.6]
       K20739  E3.4.22.30; caricain [EC:3.4.22.30]
       K20740  PPIV; glycyl endopeptidase [EC:3.4.22.25]
       K16292  CEP, CYSEP; KDEL-tailed cysteine endopeptidase [EC:3.4.22.-]
       K01363  CTSB; cathepsin B [EC:3.4.22.1]
       K01275  CTSC; cathepsin C [EC:3.4.14.1]
       K01373  CTSF; cathepsin F [EC:3.4.22.41]
       K01366  CTSH; cathepsin H [EC:3.4.22.16]
       K01371  CTSK; cathepsin K [EC:3.4.22.38]
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K09600  CTSM; cathepsin M [EC:3.4.22.-]
       K01374  CTSO; cathepsin O [EC:3.4.22.42]
       K09599  CTSP; cathepsin P [EC:3.4.22.-]
       K24378  CTSQ; cathepsin Q [EC:3.4.22.-]
       K09601  CTSR; cathepsin R [EC:3.4.22.-]
       K01368  CTSS; cathepsin S [EC:3.4.22.27]
       K01375  CTSL2, CTSV; cathepsin V [EC:3.4.22.43]
       K08569  CTSW; cathepsin W [EC:3.4.22.-]
       K08568  CTSZ; cathepsin X [EC:3.4.18.1]
       K24379  CTS8; cathepsin 8 [EC:3.4.22.-]
       K25899  GCP1, RDL1; germination-specific cysteine protease 1 [EC:3.4.22.-]
       K08570  EHCP; histolysain [EC:3.4.22.35]
       K13441  RCR3; cysteine protease
       K25900  RD21; cysteine proteinase RD21 [EC:3.4.22.-]
       K16290  XCP; xylem cysteine proteinase [EC:3.4.22.-]
       K08571  E3.4.22.51; cruzipain [EC:3.4.22.51]
       K13538  CPA; cysteine peptidase A [EC:3.4.22.-]
       K13537  CPB; cysteine peptidase B [EC:3.4.22.-]
       K08572  CPC; cysteine peptidase C [EC:3.4.22.-]
       K20741  VCATH; Baculoviridae V-cath endopeptidase [EC:3.4.22.50]
       K24271  Testin; testin-2
       K01372  BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40]
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K08573  CAPN3; calpain-3 [EC:3.4.22.54]
       K08574  CAPN5; calpain-5 [EC:3.4.22.-]
       K08575  CAPN6; calpain-6 [EC:3.4.22.-]
       K08576  CAPN7; calpain-7 [EC:3.4.22.-]
       K08577  CAPN8; calpain-8 [EC:3.4.22.-]
       K08578  CAPN9; calpain-9 [EC:3.4.22.-]
       K08579  CAPN10; calpain-10 [EC:3.4.22.-]
       K08580  CAPN11; calpain-11 [EC:3.4.22.-]
       K04740  CAPN12; calpain-12 [EC:3.4.22.-]
       K08581  CAPN13; calpain-13 [EC:3.4.22.-]
       K13442  CAPN14; calpain-14 [EC:3.4.22.-]
       K08582  CAPN15; calpain-15 [EC:3.4.22.-]
       K08583  CAPNS1, CAPN4; calpain, small subunit 1
       K08584  CAPNS2; calpain, small subunit 2
       K08585  CAPNN; calpain, invertebrate [EC:3.4.22.-]
       K25378  DEK1; calpain-type cysteine protease DEK1 [EC:3.4.22.-]
       K08586  tpr; thiol protease [EC:3.4.22.-]
       K25299  3C; Enterovirus protease 3C [EC:3.4.22.28]
       K25922  3C; Hepatitis A virus protease 3C [EC:3.4.22.28]
       K25293  2A; Enterovirus protease 2A [EC:3.4.22.29]
       K26801  NIa-pro; Potyvirus nuclear-inclusion-a endopeptidase [EC:3.4.22.44]
       K26012  L3; Adenoviridae endopeptidase [EC:3.4.22.39]
       K25923  nsP2; Alphavirus protease nsP2 [EC:3.4.22.-]
       K01364  speB; streptopain [EC:3.4.22.10]
       K08587  cloSI; clostripain [EC:3.4.22.8]
       K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
       K05609  UCHL3, YUH1; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
       K08588  BAP1, UCHL2; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
       K05610  UCHL5, UCH37; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
       K01369  LGMN; legumain [EC:3.4.22.34]
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K02186  CASP2; caspase 2 [EC:3.4.22.55]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04394  CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
       K04395  CASP5; caspase 5 [EC:3.4.22.58]
       K04396  CASP6; caspase 6 [EC:3.4.22.59]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K04401  CASP14; caspase 14 [EC:3.4.22.-]
       K13521  CASP15; caspase 15
       K20106  CED-3; cell death protein 3
       K20008  DCP1; death caspase-1 [EC:3.4.22.-]
       K20009  DRONC; caspase Dronc [EC:3.4.22.-]
       K20010  STRICA; Ser/Thr-rich caspase [EC:3.4.22.-]
       K04489  CASP3A; caspase 3A [EC:3.4.22.-]
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K22684  MCA1; metacaspase-1 [EC:3.4.22.-]
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K01304  pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
       K25013  nsp3; SARS coronavirus non-structural protein 3 [EC:3.4.19.12]
       K25924  nsP3; Alphacoronavirus papain-like proteinase 1/2 [EC:3.4.19.12 3.4.22.-]
       K11836  USP5_13, UBP14; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
       K11870  UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
       K11837  USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
       K11835  USP4_11, UBP12; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
       K11839  USP8, UBP5; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
       K11833  USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
       K11843  USP14, UBP6; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
       K11840  USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
       K11841  USP10, UBP3; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
       K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
       K11842  USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
       K11844  USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
       K21343  USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
       K11845  USP17, DUB3; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
       K11847  USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
       K11848  USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
       K11986  USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
       K11846  USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
       K21634  USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
       K11366  USP22_27_51, UBP8; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
       K11849  USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
       K11850  USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
       K11855  USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
       K21122  USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
       K11857  USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
       K11854  USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
       K11834  USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
       K11851  USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
       K11853  USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
       K11858  USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
       K11869  USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
       K11852  USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
       K11873  UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
       K11856  USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
       K11871  UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.4.19.12]
       K11872  UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
       K11874  UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
       K08589  rgpA_B; gingipain R [EC:3.4.22.37]
       K19237  kgp; gingipain K [EC:3.4.22.47]
       K01307  GGH; gamma-glutamyl hydrolase [EC:3.4.19.9]
       K01951  guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
       K01948  CPS1; carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
       K11540  CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
       K09473  puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
       K23150  E3.5.1.129; N5-(cytidine 5'-diphosphoramidyl)-L-glutamine hydrolase [EC:3.5.1.129]
       K07010  K07010; putative glutamine amidotransferase
       K25925  p150; Rubella virus protease/methyltransferase p150 [EC:3.4.22.-]
       K25015  nsp5; SARS coronavirus 3C-like proteinase [EC:3.4.22.69]
       K25926  nsp5; Alphacoronavirus 3C-like proteinase [EC:3.4.22.-]
       K25325  NS6; Norovirus 3C-like protease [EC:3.4.22.66]
       K12292  comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]
       K20344  blpA, lagD; ATP-binding cassette, subfamily C, bacteriocin exporter
       K13409  cvaB, mchF, raxB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
       K19223  lytF, cwlE; peptidoglycan DL-endopeptidase LytF [EC:3.4.-.-]
       K19224  lytE, cwlF; peptidoglycan DL-endopeptidase LytE [EC:3.4.-.-]
       K13694  mepS, spr; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]
       K19220  cwlS; peptidoglycan DL-endopeptidase CwlS [EC:3.4.-.-]
       K21471  cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
       K20742  ykfC; gamma-D-glutamyl-L-lysine dipeptidyl-peptidase [EC:3.4.14.13]
       K21473  ripA; peptidoglycan DL-endopeptidase RipA [EC:3.4.-.-]
       K21474  ripB; peptidoglycan DL-endopeptidase RipB [EC:3.4.-.-]
       K19303  mepH; murein DD-endopeptidase [EC:3.4.-.-]
       K13695  nlpC; probable lipoprotein NlpC
       K00764  purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
       K00265  gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
       K00284  GLU, gltS; glutamate synthase (ferredoxin) [EC:1.4.7.1]
       K00820  glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
       K01953  asnB, ASNS; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
       K10852  PENDE; isopenicillin-N N-acyltransferase [EC:2.3.1.164]
       K19200  IAL; isopenicillin-N N-acyltransferase like protein
       K06224  HH; hedgehog
       K11988  SHH; sonic hedgehog
       K11989  IHH; indian hedgehog
       K11990  DHH; desert hedgehog
       K08258  sspB2, sspP, scpA; staphopain A [EC:3.4.22.48]
       K13715  sspB; staphopain B [EC:3.4.22.-]
       K08592  SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
       K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
       K08593  SENP3; sentrin-specific protease 3 [EC:3.4.22.68]
       K08594  SENP5; sentrin-specific protease 5 [EC:3.4.22.68]
       K08595  SENP6; sentrin-specific protease 6 [EC:3.4.22.68]
       K08596  SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
       K08597  SENP8, NEDP1, DEN1; sentrin-specific protease 8 [EC:3.4.22.68]
       K02365  ESP1; separase [EC:3.4.22.49]
       K08342  ATG4; cysteine protease ATG4 [EC:3.4.22.-]
       K08598  yopJ; YopJ protease family
       K26818  pfpI; archaeal arginyl aminopeptidase [EC:3.4.11.27]
       K05687  PARK7; protein DJ-1 [EC:3.5.1.124]
       K05523  hchA; D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124]
       K05520  yhbO; deglycase [EC:3.5.1.124]
       K18881  DJ1D; D-lactate dehydratase [EC:4.2.1.130]
       K03152  thiJ; protein deglycase [EC:3.5.1.124]
       K18199  inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
       K25927  I7L; Poxviridae core protease I7 [EC:3.4.22.-]
       K08599  yopT; YopT peptidase [EC:3.4.22.-]
       K26083  ibpA, pfhB2; protein adenylyltransferase / cysteine protease [EC:2.7.7.108 3.4.22.-]
       K13440  avrPphB; cysteine protease avirulence protein AvrPphB [EC:3.4.22.-]
       K24041  yxeI; penicillin V amidase [EC:3.5.1.11]
       K01442  cbh; choloylglycine hydrolase [EC:3.5.1.24]
       K07284  srtA; sortase A [EC:3.4.22.70]
       K08600  srtB; sortase B [EC:3.4.22.71]
       K24447  artA; archaeosortase A [EC:3.4.22.-]
       K26423  S273R; Asfivirus cysteine protease S273R [EC:3.4.22.-]
       K11860  OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
       K11862  ZRANB1, TRABID; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
       K11861  VCPIP1, VCIP135; deubiquitinating protein VCIP135 [EC:3.4.19.12]
       K09602  OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
       K09603  OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
       K08601  CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
       K08659  pepDA, pepDB; dipeptidase [EC:3.4.-.-]
       K14358  SCRN; secernin
       K13439  avrRpt2; cysteine protease avirulence protein AvrRpt2 [EC:3.4.22.-]
       K07813  agrB; accessory gene regulator B
       K21075  UL36, UL48; Herpesviridae large tegument protein deneddylase [EC:3.4.19.12 3.4.22.-]
       K24154  UFSP1; Ufm1-specific protease 1
       K01376  UFSP2; Ufm1-specific protease 2 [EC:3.4.22.-]
       K18015  elaD, sseL; deubiquitinase [EC:3.4.22.-]
       K16291  erfK; L,D-transpeptidase ErfK/SrfK
       K19234  ynhG; L,D-transpeptidase YnhG
       K19235  ybiS; L,D-transpeptidase YbiS
       K19236  ycfS; L,D-transpeptidase YcfS
       K21470  ycbB; L,D-transpeptidase YcbB
       K25587  E3.4.17.25; glutathione-S-conjugate glycine hydrolase [EC:3.4.17.25]
       K13716  OTUD1; OTU domain-containing protein 1 [EC:3.4.19.12]
       K13717  OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
       K13718  OTUD4; OTU domain-containing protein 4 [EC:3.4.19.12]
       K12655  OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.4.19.12]
       K11863  ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
       K15235  JOSD; josephin [EC:3.4.19.12]
       K13719  OTU1, YOD1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
       K12348  ASAH1; acid ceramidase [EC:3.5.1.23]
       K13720  NAAA; N-(long-chain-acyl)ethanolamine deacylase [EC:3.5.1.60]
       K22762  DESI1, PPPDE2; desumoylating isopeptidase 1 [EC:3.4.-.-]
       K22763  DESI2, PPPDE1; deubiquitinase DESI2 [EC:3.4.19.12]
       K23008  USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]
       K24456  KY; kyphoscoliosis peptidase [EC:3.4.-.-]
       K20743  SGP; scytalidopepsin B [EC:3.4.23.32 3.4.26.2]
       K25185  TRABD2; metalloprotease TIKI [EC:3.4.-.-]
       K08658  RCE1, FACE2; intramembrane prenyl-peptidase [EC:3.4.26.1]
       K07052  K07052; CAAX protease family protein
       K11140  ANPEP, CD13; aminopeptidase N [EC:3.4.11.2]
       K11141  ENPEP, CD249; glutamyl aminopeptidase [EC:3.4.11.7]
       K01254  LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
       K01256  pepN; aminopeptidase N [EC:3.4.11.2]
       K13721  APE2; aminopeptidase 2 [EC:3.4.11.-]
       K01306  TRHDE; pyroglutamyl-peptidase II [EC:3.4.19.6]
       K08776  NPEPPS; puromycin-sensitive aminopeptidase [EC:3.4.11.14]
       K01257  LNPEP; cystinyl aminopeptidase [EC:3.4.11.3]
       K01260  RNPEP; aminopeptidase B [EC:3.4.11.6]
       K09604  ARTS1; adipocyte-derived leucine aminopeptidase [EC:3.4.11.-]
       K13722  trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-]
       K09605  RNPEPL1; arginyl aminopeptidase-like 1 [EC:3.4.11.-]
       K13723  ERAP2; endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-]
       K13724  AQPEP; aminopeptidase Q [EC:3.4.11.-]
       K09606  C9ORF3; aminopeptidase O [EC:3.4.11.-]
       K13725  PFAM1; M1-family aminopeptidase [EC:3.4.11.-]
       K03128  TAF2; transcription initiation factor TFIID subunit 2
       K01283  ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
       K09708  ACE2, ACEH; angiotensin-converting enzyme 2 [EC:3.4.17.23]
       K01392  THOP1; thimet oligopeptidase [EC:3.4.24.15]
       K01393  NLN; neurolysin [EC:3.4.24.16]
       K01405  PRD1; saccharolysin [EC:3.4.24.37]
       K01414  prlC; oligopeptidase A [EC:3.4.24.70]
       K01284  dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
       K01410  MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]
       K13726  MEPB; metallopeptidase MepB [EC:3.4.24.-]
       K08602  pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]
       K08603  npr; thermolysin [EC:3.4.24.27]
       K08604  hap, nprV; vibriolysin [EC:3.4.24.25]
       K01399  lasB; pseudolysin [EC:3.4.24.26]
       K08605  gelE; coccolysin [EC:3.4.24.30]
       K19351  mpl; zinc metalloproteinase [EC:3.4.24.-]
       K01401  aur; aureolysin [EC:3.4.24.29]
       K08777  nprB; neutral peptidase B [EC:3.4.24.-]
       K01400  nprE; bacillolysin [EC:3.4.24.28]
       K20273  zmpA; zinc metalloprotease ZmpA
       K20274  zmpB; zinc metalloprotease ZmpB
       K20744  npr; mycolysin [EC:3.4.24.31]
       K09607  ina; immune inhibitor A [EC:3.4.24.-]
       K01416  snpA; snapalysin [EC:3.4.24.77]
       K01404  GP63; leishmanolysin [EC:3.4.24.36]
       K13539  LMLN; leishmanolysin-like peptidase [EC:3.4.24.-]
       K01387  colA; microbial collagenase [EC:3.4.24.3]
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01397  MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
       K01402  MMP8; matrix metalloproteinase-8 (neutrophil collagenase) [EC:3.4.24.34]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K01396  MMP10; matrix metalloproteinase-10 (stromelysin 2) [EC:3.4.24.22]
       K07993  MMP11; matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-]
       K01413  MMP12; matrix metalloproteinase-12 (macrophage elastase) [EC:3.4.24.65]
       K07994  MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
       K07763  MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
       K07995  MMP15; matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-]
       K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
       K07997  MMP17; matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-]
       K07998  MMP19, MMP18; matrix metalloproteinase-19 (RASI) [EC:3.4.24.-]
       K07999  MMP20; matrix metalloproteinase-20 (enamelysin) [EC:3.4.24.-]
       K08000  MMP21; matrix metalloproteinase-21 [EC:3.4.24.-]
       K08001  MMP23; matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-]
       K08002  MMP24; matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-]
       K08003  MMP25; matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-]
       K08004  MMP26; matrix metalloproteinase-26 (matrilysin-2, endometase) [EC:3.4.24.-]
       K08005  MMP27; matrix metalloproteinase-27 [EC:3.4.24.-]
       K08006  MMP28; matrix metalloproteinase-28 (epilysin) [EC:3.4.24.-]
       K07761  5MMP; metalloendoproteinase 5-MMP [EC:3.4.24.-]
       K01406  prtC; serralysin [EC:3.4.24.40]
       K19957  HE; envelysin [EC:3.4.24.12]
       K19959  bftP; fragilysin [EC:3.4.24.74]
       K08076  E3.4.24.21; astacin [EC:3.4.24.21]
       K08778  ASTL; astacin-like metalloendopeptidase [EC:3.4.-.-]
       K01395  MEP1A; meprin A [EC:3.4.24.18]
       K08606  MEP1B; meprin B [EC:3.4.24.63]
       K18542  LCE; choriolysin L [EC:3.4.24.66]
       K18543  HCE; choriolysin H [EC:3.4.24.67]
       K05502  BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
       K13045  tld; tolloid [EC:3.4.24.-]
       K13046  tok; tolkin [EC:3.4.24.-]
       K09608  TLL1; tolloid-like protein 1 [EC:3.4.24.-]
       K13047  TLL2; tolloid-like protein 2 [EC:3.4.24.-]
       K20138  P40; flavastacin [EC:3.4.24.76]
       K20139  JG; jararhagin [EC:3.4.24.73]
       K20745  E3.4.24.49; bothropasin [EC:3.4.24.49]
       K20746  E3.4.24.42; atrolysin C [EC:3.4.24.42]
       K20747  E3.4.24.43; atroxase [EC:3.4.24.43]
       K21897  E3.4.24.52; trimerelysin I [EC:3.4.24.52]
       K20748  E3.4.24.58; russellysin [EC:3.4.24.58]
       K08607  ADAM1; disintegrin and metalloproteinase domain-containing protein 1 [EC:3.4.24.-]
       K06833  ADAM2; disintegrin and metalloproteinase domain-containing protein 2 [EC:3.4.24.-]
       K16071  ADAM7; disintegrin and metalloproteinase domain-containing protein 7 [EC:3.4.24.-]
       K06540  ADAM8, CD156a; disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-]
       K06834  ADAM9; disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-]
       K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
       K16067  ADAM11; disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-]
       K06835  ADAM12; disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-]
       K06836  ADAM15; disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]
       K06059  ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
       K16909  ADAM18; disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-]
       K08608  ADAM19; disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-]
       K08609  ADAM20; disintegrin and metalloproteinase domain-containing protein 20 [EC:3.4.24.-]
       K08610  ADAM21; disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-]
       K16068  ADAM22; disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-]
       K06837  ADAM23; disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-]
       K08611  ADAM24; disintegrin and metalloproteinase domain-containing protein 24 [EC:3.4.24.-]
       K08612  ADAM25; disintegrin and metalloproteinase domain-containing protein 25 [EC:3.4.24.-]
       K08613  ADAM26; disintegrin and metalloproteinase domain-containing protein 26 [EC:3.4.24.-]
       K08614  ADAM28; disintegrin and metalloproteinase domain-containing protein 28 [EC:3.4.24.-]
       K16069  ADAM29; disintegrin and metalloproteinase domain-containing protein 29 [EC:3.4.24.-]
       K08615  ADAM30; disintegrin and metalloproteinase domain-containing protein 30 [EC:3.4.24.-]
       K16070  ADAM32; disintegrin and metalloproteinase domain-containing protein 32 [EC:3.4.24.-]
       K08616  ADAM33; disintegrin and metalloproteinase domain-containing protein 33 [EC:3.4.24.-]
       K08617  ADAMTS1; a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-]
       K08618  ADAMTS2; a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14]
       K08619  ADAMTS3; a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-]
       K07764  ADAMTS4; a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82]
       K08620  ADAMTS5; a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-]
       K08621  ADAMTS6; a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-]
       K08622  ADAMTS7; a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-]
       K08623  ADAMTS8; a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-]
       K08624  ADAMTS9; a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-]
       K08625  ADAMTS10; a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]
       K08626  ADAMTS12; a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-]
       K08627  ADAMTS13; a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87]
       K08628  ADAMTS14; a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-]
       K08629  ADAMTS15; a disintegrin and metalloproteinase with thrombospondin motifs 15 [EC:3.4.24.-]
       K08630  ADAMTS16; a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-]
       K08631  ADAMTS17; a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-]
       K08632  ADAMTS18; a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-]
       K08633  ADAMTS19; a disintegrin and metalloproteinase with thrombospondin motifs 19 [EC:3.4.24.-]
       K09609  ADAMTS20; a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-]
       K08634  ADAMDEC1; ADAM-like, decysin 1 [EC:3.4.24.-]
       K01389  MME, CD10; neprilysin [EC:3.4.24.11]
       K08635  MMEL1, NEP; neprilysin [EC:3.4.24.11]
       K01415  ECE; endothelin-converting enzyme [EC:3.4.24.71]
       K07386  pepO; putative endopeptidase [EC:3.4.24.-]
       K09610  ECEL1; endothelin-converting enzyme-like 1 [EC:3.4.24.-]
       K06577  KEL, CD238; Kell blood group glycoprotein [EC:3.4.24.-]
       K08636  PHEX; phosphate-regulating neutral endopeptidase [EC:3.4.24.-]
       K08779  CPA1; carboxypeptidase A1 [EC:3.4.17.1]
       K08780  CPA3; carboxypeptidase A3 [EC:3.4.17.1]
       K08781  CPA5; carboxypeptidase A5 [EC:3.4.17.1]
       K08782  CPA6; carboxypeptidase A6 [EC:3.4.17.1]
       K01298  CPA2; carboxypeptidase A2 [EC:3.4.17.15]
       K08637  CPA4; carboxypeptidase A4 [EC:3.4.17.-]
       K01290  CPAN; carboxypeptidase A, invertebrate [EC:3.4.17.-]
       K01291  CPB1; carboxypeptidase B [EC:3.4.17.2]
       K01300  CPB2; carboxypeptidase B2 [EC:3.4.17.20]
       K08783  ECM14; extracellular matrix protein 14 [EC:3.4.17.-]
       K07752  CPD; carboxypeptidase D [EC:3.4.17.22]
       K01294  CPE; carboxypeptidase E [EC:3.4.17.10]
       K01296  CPM; carboxypeptidase M [EC:3.4.17.12]
       K01292  CPN1; carboxypeptidase N catalytic subunit [EC:3.4.17.3]
       K13023  CPN2; carboxypeptidase N regulatory subunit
       K23009  CPO; carboxypeptidase O [EC:3.4.17.-]
       K05996  cpt; carboxypeptidase T [EC:3.4.17.18]
       K08638  CPXM1; carboxypeptidase X1 [EC:3.4.17.-]
       K08639  CPXM2; carboxypeptidase X2
       K13022  CPZ; carboxypeptidase Z [EC:3.4.17.-]
       K23435  AGTPBP1, CCP1; cytosolic carboxypeptidase protein 1 [EC:3.4.17.24]
       K23436  AGBL1, CCP4; cytosolic carboxypeptidase protein 4 [EC:3.4.17.24]
       K23437  AGBL2_3, CCP2_3; cytosolic carboxypeptidase protein 2/3 [EC:3.4.17.-]
       K23438  AGBL5, CCP5; cytosolic carboxypeptidase protein 5 [EC:3.4.17.24]
       K23439  AGBL4, CCP6; cytosolic carboxypeptidase protein 6 [EC:3.4.17.24]
       K01308  yqgT; g-D-glutamyl-meso-diaminopimelate peptidase [EC:3.4.19.11]
       K08640  E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
       K07260  vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
       K08641  vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
       K18866  vanXY; zinc D-Ala-D-Ala dipeptidase/carboxypeptidase [EC:3.4.13.22 3.4.17.14]
       K17733  cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
       K01407  ptrA; protease III [EC:3.4.24.55]
       K01408  IDE, ide; insulysin [EC:3.4.24.56]
       K01411  NRD1; nardilysin [EC:3.4.24.61]
       K25894  SPP; stromal processing peptidase, chloroplastic [EC:3.4.24.-]
       K01422  AXL1; protease AXL1 [EC:3.4.24.-]
       K06972  PITRM1, PreP, CYM1; presequence protease [EC:3.4.24.-]
       K01412  PMPCA, MAS2; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
       K17732  PMPCB, MAS1; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K07263  pqqL; zinc protease [EC:3.4.24.-]
       K11142  LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
       K01255  CARP, pepA; leucyl aminopeptidase [EC:3.4.11.1]
       K07751  pepB; PepB aminopeptidase [EC:3.4.11.23]
       K09611  NPEPL1; probable aminopeptidase NPEPL1 [EC:3.4.11.-]
       K01268  LAP4; aminopeptidase I [EC:3.4.11.22]
       K01267  DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
       K01273  DPEP; membrane dipeptidase [EC:3.4.13.19]
       K01295  cpg; glutamate carboxypeptidase [EC:3.4.17.11]
       K01293  E3.4.17.4; Gly-Xaa carboxypeptidase [EC:3.4.17.4]
       K01274  pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-]
       K01439  dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
       K13049  PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]
       K14677  ACY1; aminoacylase [EC:3.5.1.14]
       K14262  DUG2; di- and tripeptidase [EC:3.4.-.-]
       K01258  pepT; tripeptide aminopeptidase [EC:3.4.11.4]
       K01270  pepD; dipeptidase D [EC:3.4.13.-]
       K13048  cps; carboxypeptidase Ss1 [EC:3.4.17.-]
       K01436  yhaA; amidohydrolase [EC:3.5.1.-]
       K21613  scmP; N-acetylcysteine deacetylase [EC:3.5.1.-]
       K01451  hipO; hippurate hydrolase [EC:3.5.1.32]
       K12940  abgA; aminobenzoyl-glutamate utilization protein A
       K12941  abgB; aminobenzoyl-glutamate utilization protein B
       K25379  iaaH; indole-3-acetyl-L-aspartate hydrolase [EC:3.5.1.134]
       K26141  PM20D2; Xaa-Arg dipeptidase [EC:3.4.13.4]
       K14664  ILR1; IAA-amino acid hydrolase [EC:3.5.1.-]
       K21604  IAR3, ILL6; jasmonoyl-L-amino acid hydrolase [EC:3.5.1.127]
       K14665  amhX; amidohydrolase [EC:3.5.1.-]
       K05823  dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]
       K08660  CNDP2; cytosolic nonspecific dipeptidase [EC:3.4.13.18]
       K05604  CNDP1; beta-Ala-His dipeptidase [EC:3.4.13.20]
       K15428  DUG1; Cys-Gly metallodipeptidase DUG1 [EC:3.4.13.-]
       K02083  allC; allantoate deiminase [EC:3.5.3.9]
       K23980  tpdA; cysteinylglycine-S-conjugate dipeptidase [EC:3.4.13.23]
       K20749  E3.4.24.32; beta-lytic metalloendopeptidase [EC:3.4.24.32]
       K08642  lasA; LasA protease [EC:3.4.24.-]
       K21472  lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
       K19304  mepM; murein DD-endopeptidase [EC:3.4.24.-]
       K08259  lytM; lysostaphin [EC:3.4.24.75]
       K01265  map; methionyl aminopeptidase [EC:3.4.11.18]
       K01271  pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
       K14213  PEPD; Xaa-Pro dipeptidase [EC:3.4.13.9]
       K01262  pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
       K14208  XPNPEP2; Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]
       K18573  ICP55; intermediate cleaving peptidase 55 [EC:3.4.11.26]
       K08326  ypdF; aminopeptidase [EC:3.4.11.-]
       K01390  iga; IgA-specific metalloendopeptidase [EC:3.4.24.13]
       K08643  zmpB; zinc metalloprotease ZmpB [EC:3.4.24.-]
       K08644  tetX; tentoxilysin [EC:3.4.24.68]
       K06011  boNT; botulinum neurotoxin [EC:3.4.24.69]
       K01264  APE3; aminopeptidase Y [EC:3.4.11.15]
       K05994  E3.4.11.10; bacterial leucyl aminopeptidase [EC:3.4.11.10]
       K19702  E3.4.11.24; aminopeptidase S [EC:3.4.11.24]
       K09612  iap; alkaline phosphatase isozyme conversion protein [EC:3.4.11.-]
       K19701  ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10]
       K14592  FOLH1, GCPII; glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
       K01301  NAALAD; N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21]
       K01302  CPQ; carboxypeptidase Q [EC:3.4.17.-]
       K06503  TFRC, CD71; transferrin receptor
       K23910  TFR2; transferrin receptor protein 2
       K00683  QPCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]
       K26499  NCLN; BOS complex subunit NCLN
       K19689  ampS, pepS, ampT; aminopeptidase [EC:3.4.11.-]
       K01299  E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
       K08645  lef; anthrax lethal toxin endopeptidase [EC:3.4.24.83]
       K20109  zmp1; Pro-Pro endopeptidase [EC:3.4.24.89]
       K19305  NPII; deuterolysin [EC:3.4.24.39]
       K08646  MEP; peptidyl-Lys metalloendopeptidase [EC:3.4.24.20]
       K01417  MEP; extracellular elastinolytic metalloproteinase [EC:3.4.24.-]
       K01305  iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]
       K03798  ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]
       K08956  AFG3; AFG3 family protein [EC:3.4.24.-]
       K08955  YME1; ATP-dependent metalloprotease [EC:3.4.24.-]
       K09552  SPG7; spastic paraplegia 7 [EC:3.4.24.-]
       K01261  pepA; glutamyl aminopeptidase [EC:3.4.11.7]
       K18530  frvX; putative aminopeptidase FrvX [EC:3.4.11.-]
       K20608  tet; tetrahedral aminopeptidase [EC:3.4.11.-]
       K20609  sgcX; putative aminopeptidase [EC:3.4.11.-]
       K01269  yhfE; aminopeptidase [EC:3.4.11.-]
       K07762  PAPPA; pappalysin-1 [EC:3.4.24.79]
       K08647  PAPPA2; pappalysin-2 [EC:3.4.24.-]
       K25978  G1L; Poxviridae metalloendopeptidase G1 [EC:3.4.24.-]
       K06013  STE24; STE24 endopeptidase [EC:3.4.24.84]
       K03799  htpX; heat shock protein HtpX [EC:3.4.24.-]
       K23010  OMA1; metalloendopeptidase OMA1, mitochondrial [EC:3.4.24.-]
       K07387  K07387; metalloprotease [EC:3.4.24.-]
       K01423  bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
       K01277  DPP3; dipeptidyl-peptidase III [EC:3.4.14.4]
       K07765  MBTPS2; S2P endopeptidase [EC:3.4.24.85]
       K06402  spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]
       K11749  rseP; regulator of sigma E protease [EC:3.4.24.-]
       K25380  EGY; zinc metalloprotease EGY, chloroplastic [EC:3.4.24.-]
       K16922  yydH; putative peptide zinc metalloprotease protein
       K06974  amzA, AMZ2, AMZ1; archaemetzincin [EC:3.4.-.-]
       K16203  dppA1; D-amino peptidase [EC:3.4.11.-]
       K02172  blaR1; bla regulator protein blaR1
       K02547  mecR1; methicillin resistance protein
       K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
       K09613  COPS5, CSN5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
       K11867  STAMBPL1; AMSH-like protease [EC:3.4.19.12]
       K11864  BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
       K11865  MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]
       K11866  STAMBP, AMSH; STAM-binding protein [EC:3.4.19.12]
       K20110  JAMM1; desampylase [EC:3.4.19.15]
       K23743  E3.4.24.33; peptidyl-Asp metalloendopeptidase [EC:3.4.24.33]
       K06336  tasA, cotN; spore coat-associated protein N
       K07261  mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]
       K22685  WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
       K24131  prsW; protease PrsW [EC:3.4.-.-]
       K23655  nleC; T3SS secreted effector NleC
       K23941  pipA, gogA, gtgA; PipA/GogA/GtgA family effector protease
       K21429  impA; immunomodulating metalloprotease
       K09933  mtfA; MtfA peptidase
       K26802  alpha; Alphanodavirus capsid protein alpha [EC:3.4.23.44]
       K25928  VP0; Enterovirus capsid protein VP0
       K01266  dmpA, dap; D-aminopeptidase [EC:3.4.11.19]
       K20750  bapA; beta-peptidyl aminopeptidase [EC:3.4.11.25]
       K08460  ADGRA1, GPR123; adhesion G protein-coupled receptor A1
       K08461  ADGRA2, GPR124; adhesion G protein-coupled receptor A2
       K08462  ADGRA3, GPR125; adhesion G protein-coupled receptor A3
       K04596  ADGRB1, BAI1; adhesion G protein-coupled receptor B1
       K04597  ADGRB2, BAI2; adhesion G protein-coupled receptor B2
       K04598  ADGRB3, BAI3; adhesion G protein-coupled receptor B3
       K08465  ADGRD1, GPR133; adhesion G-protein coupled receptor D1
       K08466  ADGRD2, GPR144; adhesion G-protein coupled receptor D2
       K04591  ADGRE1, EMR1; adhesion G protein-coupled receptor E1
       K08443  ADGRE2, EMR2, CD312; adhesion G protein-coupled receptor E2
       K08444  ADGRE3, EMR3; adhesion G protein-coupled receptor E3
       K08445  ADGRE4, EMR4; adhesion G protein-coupled receptor E4
       K08446  ADGRE5, CD97; CD97 antigen
       K08453  ADGRF1, GPR110; adhesion G-protein coupled receptor F1
       K08454  ADGRF2, GPR111; adhesion G-protein coupled receptor F2
       K08456  ADGRF3, GPR113; adhesion G-protein coupled receptor F3
       K08457  ADGRF4, GPR115; adhesion G-protein coupled receptor F4
       K08458  ADGRF5, GPR116; adhesion G-protein coupled receptor F5
       K08450  ADGRG1, GPR56; adhesion G-protein coupled receptor G1
       K08451  ADGRG2, GPR64; adhesion G-protein coupled receptor G2
       K08452  ADGRG3, GPR97; adhesion G-protein coupled receptor G3
       K08455  ADGRG4, GPR112; adhesion G-protein coupled receptor G4
       K08459  ADGRG5, GPR114; adhesion G-protein coupled receptor G5
       K08463  ADGRG6, GPR126; adhesion G-protein coupled receptor G6
       K08464  ADGRG7, GPR128; adhesion G-protein coupled receptor G7
       K04592  ADGRL1, LPHN1; adhesion G protein-coupled receptor L1
       K04593  ADGRL2, LPHN2; adhesion G protein-coupled receptor L2
       K04594  ADGRL3, LPHN3; adhesion G protein-coupled receptor L3
       K04595  ADGRL4, ELTD1; adhesion G protein-coupled receptor L4
       K18263  ADGRV1, GPR98, USH2C; adhesion G-protein coupled receptor V1
       K04600  CELSR1; cadherin EGF LAG seven-pass G-type receptor 1
       K04601  CELSR2; cadherin EGF LAG seven-pass G-type receptor 2
       K04602  CELSR3; cadherin EGF LAG seven-pass G-type receptor 3
       K01310  CTRB; chymotrypsin [EC:3.4.21.1]
       K08661  MCPT1; mast cell peptidase 1 [EC:3.4.21.-]
       K08662  MCPT2; mast cell peptidase 2 [EC:3.4.21.-]
       K01340  E3.4.21.59; tryptase [EC:3.4.21.59]
       K09614  CORIN; atrial natriuretic peptide-converting enzyme [EC:3.4.21.-]
       K01362  OVCH; ovochymase [EC:3.4.21.-]
       K20111  OVCH2; oviductin [EC:3.4.21.120]
       K09615  TPSG1; tryptase gamma 1 [EC:3.4.21.-]
       K08648  HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
       K20751  E3.4.21.99; spermosin [EC:3.4.21.99]
       K20752  E3.4.21.49; hypodermin C [EC:3.4.21.49]
       K01312  PRSS1_2_3; trypsin [EC:3.4.21.4]
       K01316  TMPRSS15, PRSS7; enterokinase [EC:3.4.21.9]
       K08664  PRSS8; prostasin [EC:3.4.21.-]
       K09624  PRSS12; neurotrypsin [EC:3.4.21.-]
       K09625  PRSS21; testisin [EC:3.4.21.-]
       K09626  PRSS22, BSSP4; brain-specific serine protease 4 [EC:3.4.21.-]
       K09628  PRSS27; serine protease 27 [EC:3.4.21.-]
       K09629  PRSS33; serine protease 33 [EC:3.4.21.-]
       K09630  PRSS36; polyserase 2 [EC:3.4.21.-]
       K25708  PRSS53; serine protease 53 [EC:3.4.21.-]
       K23440  PRSS56; serine protease 56 [EC:3.4.21.-]
       K23011  PRSS57, NSP4; serine protease 57 [EC:3.4.21.-]
       K22367  PRSS58; serine protease 58 [EC:3.4.21.-]
       K01327  ELANE; leukocyte elastase [EC:3.4.21.37]
       K01319  CTSG; cathepsin G [EC:3.4.21.20]
       K01350  PRTN3; myeloblastin [EC:3.4.21.76]
       K01352  GZMA; granzyme A [EC:3.4.21.78]
       K01353  GZMB; granzyme B [EC:3.4.21.79]
       K09616  GZMH, CTSGL2; granzyme H (cathepsin G-like 2) [EC:3.4.21.-]
       K08663  GZMK; granzyme K [EC:3.4.21.-]
       K08649  GZMM; granzyme M [EC:3.4.21.-]
       K01329  CMA1; chymase [EC:3.4.21.39]
       K01326  CELA1; pancreatic elastase I [EC:3.4.21.36]
       K01346  CELA2; pancreatic elastase II [EC:3.4.21.71]
       K01345  CELA3; pancreatic endopeptidase E [EC:3.4.21.70]
       K01311  CTRC; chymotrypsin C [EC:3.4.21.2]
       K01325  KLK1_2; tissue kallikrein [EC:3.4.21.35]
       K01324  KLKB1; plasma kallikrein [EC:3.4.21.34]
       K01351  KLK3, PSA; semenogelase [EC:3.4.21.77]
       K08666  KLK4, PRSS17; kallikrein 4 [EC:3.4.21.-]
       K09617  KLK5; kallikrein 5 [EC:3.4.21.-]
       K08667  KLK6, PRSS9; kallikrein 6 [EC:3.4.21.-]
       K08668  KLK7, PRSS6; kallikrein 7 [EC:3.4.21.117]
       K08650  KLK8, PRSS19; kallikrein 8 [EC:3.4.21.118]
       K09618  KLK9; kallikrein 9 [EC:3.4.21.-]
       K09619  KLK10, PRSSL1; kallikrein 10 [EC:3.4.21.-]
       K09620  KLK11, PRSS20; kallikrein 11 [EC:3.4.21.-]
       K09462  E3.4.21.119; glandular kallikrein 13 [EC:3.4.21.119]
       K09621  KLK12; kallikrein 12 [EC:3.4.21.-]
       K09463  KLK13; kallikrein 13 [EC:3.4.21.119]
       K09622  KLK14; kallikrein 14 [EC:3.4.21.-]
       K09623  KLK15; kallikrein 15 [EC:3.4.21.-]
       K01339  KLK16; g-renin [EC:3.4.21.54]
       K20137  BX; venombin A [EC:3.4.21.74]
       K24791  C1RL; complement C1r subcomponent-like protein [EC:3.4.21.-]
       K03992  MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-]
       K03993  MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104]
       K01330  C1R; complement component 1, r subcomponent [EC:3.4.21.41]
       K01331  C1S; complement component 1, s subcomponent [EC:3.4.21.42]
       K01332  C2; complement component 2 [EC:3.4.21.43]
       K01335  CFB; complement factor B [EC:3.4.21.47]
       K01334  CFD; complement factor D [EC:3.4.21.46]
       K01333  CFI; complement factor I [EC:3.4.21.45]
       K24132  Sp7; serine protease 7 [EC:3.4.21.-]
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K01320  F7; coagulation factor VII [EC:3.4.21.21]
       K01321  F9; coagulation factor IX (Christmas factor) [EC:3.4.21.22]
       K01314  F10; coagulation factor X [EC:3.4.21.6]
       K01323  F11; coagulation factor XI [EC:3.4.21.27]
       K01328  F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38]
       K01344  PROC; protein C (activated) [EC:3.4.21.69]
       K22079  E3.4.21.84; limulus clotting factor C [EC:3.4.21.84]
       K22080  E3.4.21.85; limulus clotting factor B [EC:3.4.21.85]
       K20753  E3.4.21.86; limulus clotting enzyme [EC:3.4.21.86]
       K01317  ACR; acrosin [EC:3.4.21.10]
       K08665  HPN; hepsin [EC:3.4.21.106]
       K24133  Sb; serine proteinase stubble [EC:3.4.21.-]
       K09631  HGFAC; hepatocyte growth factor activator [EC:3.4.21.-]
       K01343  PLAT; tissue plasminogen activator [EC:3.4.21.68]
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K01315  PLG; plasminogen [EC:3.4.21.7]
       K09633  TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
       K09634  TMPRSS3; transmembrane protease serine 3 [EC:3.4.21.-]
       K09635  TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-]
       K09636  TMPRSS5; transmembrane protease serine 5 [EC:3.4.21.-]
       K09637  TMPRSS6; transmembrane protease serine 6 [EC:3.4.21.-]
       K09638  TMPRSS7; transmembrane protease serine 7 [EC:3.4.21.-]
       K09639  TMPRSS8; transmembrane protease serine 8 [EC:3.4.21.-]
       K09640  TMPRSS9; transmembrane protease serine 9 [EC:3.4.21.-]
       K09750  TMPRSS11A; transmembrane protease serine 11A [EC:3.4.21.-]
       K09751  TMPRSS11B; transmembrane protease serine 11B [EC:3.4.21.-]
       K14359  TMPRSS11C; transmembrane protease serine 11C [EC:3.4.21.-]
       K09641  TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-]
       K09642  TMPRSS11E; transmembrane protease serine 11E [EC:3.4.21.-]
       K09752  TMPRSS11F; transmembrane protease serine 11F [EC:3.4.21.-]
       K18769  TMPRSS11G; transmembrane protease serine 11G [EC:3.4.21.-]
       K09643  TMPRSS13, TMPRSS11; transmembrane protease serine 13
       K09632  CTRL; chymotrypsin-like protease [EC:3.4.21.-]
       K04775  ydgD; protease YdgD [EC:3.4.21.-]
       K08670  ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
       K20671  PSH; serine protease persephone [EC:3.4.21.-]
       K23489  SVH1, Teq; HGF/MSP/plasminogen-like protein
       K20672  SPE; spatzle-processing enzyme [EC:3.4.21.-]
       K20673  GRASS; gram-positive specific serine protease [EC:3.4.21.-]
       K20674  MODSP; modular serine protease [EC:3.4.21.-]
       K24665  AZU1; azurocidin
       K16142  HP; haptoglobin
       K23441  MST1; hepatocyte growth factor-like protein
       K09644  LPA; apolipoprotein(a) [EC:3.4.21.-]
       K20675  SPIRIT; serine protease immune response integrator
       K20677  HAYAN; serine protease Hayan [EC:3.4.21.-]
       K20676  SPHEROIDE; spheroide [EC:3.4.21.-]
       K01318  sspA; glutamyl endopeptidase [EC:3.4.21.19]
       K04771  degP, htrA; serine protease Do [EC:3.4.21.107]
       K04772  degQ, hhoA; serine protease DegQ [EC:3.4.21.-]
       K04691  hhoB, degS; serine protease DegS [EC:3.4.21.-]
       K08784  HTRA1, PRSS11; HtrA serine peptidase 1 [EC:3.4.21.-]
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K08785  HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-]
       K08786  HTRA4; HtrA serine peptidase 4 [EC:3.4.21.-]
       K23012  TYSND1; peroxisomal leader peptide-processing protease [EC:3.4.21.-]
       K25895  DEGP1; protease Do-like 1, chloroplastic [EC:3.4.21.-]
       K25896  DEGP2; protease Do-like 2, chloroplastic [EC:3.4.21.-]
       K25897  DEGP9; protease Do-like 9 [EC:3.4.21.-]
       K08372  pepD; putative serine protease PepD [EC:3.4.21.-]
       K01337  E3.4.21.50; lysyl endopeptidase [EC:3.4.21.50]
       K09627  PRSS23; serine protease 23 [EC:3.4.21.-]
       K22686  NMA111; pro-apoptotic serine protease NMA111 [EC:3.4.21.-]
       K18544  sprA; streptogrisin A [EC:3.4.21.80]
       K18545  sprB; streptogrisin B [EC:3.4.21.81]
       K18546  sprC; streptogrisin C [EC:3.4.21.-]
       K18547  sprD; streptogrisin D [EC:3.4.21.-]
       K18548  sprE; glutamyl endopeptidase II [EC:3.4.21.82]
       K20136  alpha-LP; alpha-lytic endopeptidase [EC:3.4.21.12]
       K25929  C; Alphavirus capsid protein [EC:3.4.21.90]
       K01347  iga; IgA-specific serine endopeptidase [EC:3.4.21.72]
       K25328  NS3; Flavivirus serine protease NS3 catalytic subunit [EC:3.4.21.91 3.6.1.15 5.6.2.6]
       K01342  aprE; subtilisin [EC:3.4.21.62]
       K13274  wprA; cell wall-associated protease [EC:3.4.21.-]
       K08651  E3.4.21.66; thermitase [EC:3.4.21.66]
       K13276  bpr; bacillopeptidase F [EC:3.4.21.-]
       K01361  E3.4.21.96; lactocepin [EC:3.4.21.96]
       K08652  C5AP, scpA, scpB; C5a peptidase [EC:3.4.21.110]
       K13275  isp; major intracellular serine protease [EC:3.4.21.-]
       K20754  pstI; aqualysin 1 [EC:3.4.21.111]
       K01336  PRB1; cerevisin [EC:3.4.21.48 3.4.21.-]
       K18549  ALP; oryzin [EC:3.4.21.63]
       K20486  nisP, epiP; lantibiotic leader peptide-processing serine protease [EC:3.4.21.-]
       K08653  MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
       K01341  KEX2; kexin [EC:3.4.21.61]
       K01349  FURIN, PCSK3; furin [EC:3.4.21.75]
       K01359  PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
       K01360  PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
       K08671  PCSK4; proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-]
       K08654  PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
       K08672  PCSK6; proprotein convertase subtilisin/kexin type 6 [EC:3.4.21.-]
       K08673  PCSK7; proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-]
       K13050  PCSK9; proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-]
       K14645  K14645; serine protease [EC:3.4.21.-]
       K14647  vpr; minor extracellular serine protease Vpr [EC:3.4.21.-]
       K20755  E3.4.21.121; Lys-Lys/Arg-Xaa endopeptidase [EC:3.4.21.121]
       K13277  epr; minor extracellular protease Epr [EC:3.4.21.-]
       K14743  mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-]
       K17734  aprX; serine protease AprX [EC:3.4.21.-]
       K24454  patG; thiazoline dehydrogenase / protease [EC:1.3.3.16 3.4.-.-]
       K25898  CRSP; CO(2)-response secreted protease
       K14644  OSW3, RRT12; subtilase-type proteinase RRT12 [EC:3.4.21.-]
       K01280  TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
       K01322  PREP; prolyl oligopeptidase [EC:3.4.21.26]
       K08787  STE13; dipeptidyl aminopeptidase Ste13 [EC:3.4.14.-]
       K01278  DPP4, CD26; dipeptidyl-peptidase 4 [EC:3.4.14.5]
       K08655  DPP8; dipeptidyl-peptidase 8 [EC:3.4.14.5]
       K08656  DPP9; dipeptidyl-peptidase 9 [EC:3.4.14.5]
       K01303  APEH; acylaminoacyl-peptidase [EC:3.4.19.1]
       K01282  DAP2; dipeptidyl aminopeptidase B [EC:3.4.14.-]
       K08674  FAP; fibroblast activation protein, alpha [EC:3.4.21.-]
       K01354  ptrB; oligopeptidase B [EC:3.4.21.83]
       K22582  PREPL; prolyl endopeptidase-like [EC:3.4.21.-]
       K18574  ptpA; Xaa-Xaa-Pro tripeptidyl-peptidase [EC:3.4.14.12]
       K13702  ABHD10; abhydrolase domain-containing protein 10 [EC:3.1.1.93]
       K13704  ABHD12; abhydrolase domain-containing protein 12 [EC:3.1.1.23]
       K13705  ABHD12B; abhydrolase domain-containing protein 12B [EC:3.-.-.-]
       K24083  ABHD13; abhydrolase domain-containing protein 13 [EC:3.-.-.-]
       K25824  ABHD16A; abhydrolase domain-containing protein 16A [EC:3.1.1.23 3.1.-.-]
       K25825  ABHD16B; abhydrolase domain-containing protein 16B [EC:3.-.-.-]
       K01076  ABHD17; abhydrolase domain-containing protein 17 [EC:3.1.2.22]
       K13616  AADAC; arylacetamide deacetylase [EC:3.1.1.3]
       K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
       K13289  CTSA, CPY; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
       K01288  KEX1; carboxypeptidase D [EC:3.4.16.6]
       K09645  CPVL; vitellogenic carboxypeptidase-like protein [EC:3.4.16.-]
       K09646  SCPEP1; serine carboxypeptidase 1 [EC:3.4.16.-]
       K09757  SCPL8, SNG1; serine carboxypeptidase-like 8 [EC:3.4.16.- 2.3.1.92]
       K09756  SCPL19, SNG2; serine carboxypeptidase-like 19 [EC:3.4.16.- 2.3.1.91]
       K16296  SCPL-I; serine carboxypeptidase-like clade I [EC:3.4.16.-]
       K16297  SCPL-II; serine carboxypeptidase-like clade II [EC:3.4.16.-]
       K16298  SCPL-IV; serine carboxypeptidase-like clade IV [EC:3.4.16.-]
       K07258  dacC, dacA, dacD; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
       K07262  pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
       K17382  LACTB; serine beta-lactamase-like protein LACTB, mitochondrial
       K26579  clbP; colibactin biosynthesis peptidase
       K18988  ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-]
       K21469  pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
       K07259  dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
       K01358  clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
       K01281  pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
       K01338  lon; ATP-dependent Lon protease [EC:3.4.21.53]
       K08675  PRSS15, PIM1; ATP-dependent Lon protease [EC:3.4.21.53]
       K04076  lonB; ATP-dependent Lon protease [EC:3.4.21.53]
       K04770  lonH; Lon-like ATP-dependent protease [EC:3.4.21.-]
       K07177  K07177; Lon-like protease
       K25930  assemblin; Herpesviridae assemblin [EC:3.4.21.97]
       K21078  UL80; Cytomegalovirus capsid scaffolding protein [EC:3.4.21.97]
       K26507  BVRF2; Lymphocryptovirus capsid scaffolding protein [EC:3.4.21.97]
       K01356  lexA; repressor LexA [EC:3.4.21.88]
       K03503  umuD; DNA polymerase V [EC:3.4.21.-]
       K03100  lepB; signal peptidase I [EC:3.4.21.89]
       K13280  SEC11, sipW; signal peptidase I [EC:3.4.21.89]
       K09647  IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]
       K09648  IMP2; mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-]
       K01285  PRCP; lysosomal Pro-X carboxypeptidase [EC:3.4.16.2]
       K01276  DPP7; dipeptidyl-peptidase II [EC:3.4.14.2]
       K09649  PRSS16; thymus-specific serine protease [EC:3.4.-.-]
       K26798  NS3; Bovine viral diarrhea virus 1 serine protease NS3 [EC:3.4.21.113 3.6.1.15 5.6.2.6]
       K26799  Nsp4; Equine arterivirus serine peptidase [EC:3.4.21.114]
       K01259  pip; proline iminopeptidase [EC:3.4.11.5]
       K13698  ABHD4; abhydrolase domain-containing protein 4
       K13699  ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
       K13700  ABHD6; abhydrolase domain-containing protein 6 [EC:3.1.1.23]
       K13701  ABHD8; abhydrolase domain-containing protein 8
       K13703  ABHD11; abhydrolase domain-containing protein 11
       K13706  ABHD14; abhydrolase domain-containing protein 14
       K01253  EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
       K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
       K22368  EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
       K22369  EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
       K27108  ephA_B; epoxide hydrolase A/B [EC:3.3.2.-]
       K01054  MGLL; acylglycerol lipase [EC:3.1.1.23]
       K13617  PPME1; protein phosphatase methylesterase 1 [EC:3.1.1.89]
       K03797  E3.4.21.102, prc, ctpA; carboxyl-terminal processing protease [EC:3.4.21.102]
       K23911  RBP3; retinol-binding protein 3
       K08676  tri; tricorn protease [EC:3.4.21.-]
       K01434  pac; penicillin G amidase [EC:3.5.1.11]
       K12748  gca; glutaryl-7-aminocephalosporanic-acid acylase [EC:3.5.1.93]
       K04773  sppA; protease IV [EC:3.4.21.-]
       K04774  sohB; serine protease SohB [EC:3.4.21.-]
       K21511  C; Enterobacteria phage capsid assembly protease [EC:3.4.21.-]
       K26800  VP4; Infectious pancreatic necrosis birnavirus Vp4 peptidase [EC:3.4.21.115]
       K05995  pepE; dipeptidase E [EC:3.4.13.21]
       K13282  cphB; cyanophycinase [EC:3.4.15.6]
       K05998  E3.4.21.100; pseudomonalisin [EC:3.4.21.100]
       K05999  E3.4.21.101; xanthomonalisin [EC:3.4.21.101]
       K01279  TPP1, CLN2; tripeptidyl-peptidase I [EC:3.4.14.9]
       K08677  kscP, scpA; kumamolisin [EC:3.4.21.123]
       K20756  E3.4.21.103; physarolisin [EC:3.4.21.103]
       K23461  RHO; rhomboid [EC:3.4.21.105]
       K02857  RHBDL1_2_3; rhomboid-related protein 1/2/3 [EC:3.4.21.105]
       K09651  RHBDD1, RHBDL4; rhomboid-related protein 4 [EC:3.4.21.105]
       K09652  RHBDD2, RHBDL7; rhomboid domain-containing protein 2
       K09650  PARL, PSARL, PCP1; rhomboid-like protein [EC:3.4.21.105]
       K19225  gluP; rhomboid protease GluP [EC:3.4.21.105]
       K02441  glpG; rhomboid protease GlpG [EC:3.4.21.105]
       K07059  K07059; rhomboid family protein
       K06399  spoIVB; stage IV sporulation protein B [EC:3.4.21.116]
       K19390  PA; Influenza virus polymerase acidic protein
       K01297  ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
       K26761  gp21; Straboviridae prohead core protein protease [EC:3.4.-.-]
       K06904  GP4; Escherichia/Staphylococcus phage prohead protease
       K02730  PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
       K02726  PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
       K02728  PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
       K02731  PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
       K02729  PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
       K02725  PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
       K02727  PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
       K03432  psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
       K02738  PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
       K02739  PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
       K02735  PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
       K02734  PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
       K02737  PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
       K02732  PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
       K02736  PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
       K02740  PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]
       K02741  PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]
       K02733  PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]
       K03433  psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
       K01419  hslV, clpQ; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
       K13051  ASRGL1, iaaA; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
       K08657  TASP1; taspase, threonine aspartase, 1 [EC:3.4.25.-]
       K00681  ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
       K22602  hpxW; oxamate amidohydrolase [EC:3.5.1.126]
       K18592  GGT1_5, CD224; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
       K08303  prtC, trhP; U32 family peptidase [EC:3.4.-.-]
       K24847  rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase
       K24845  ubiV; O2-independent ubiquinone biosynthesis protein UbiV
       K24844  ubiU; O2-independent ubiquinone biosynthesis protein UbiU
       K03592  pmbA; PmbA protein
       K03568  tldD; TldD protein
       K23417  SPINK1; serine protease inhibitor Kazal-type 1
       K23418  SPINK2; serine protease inhibitor Kazal-type 2
       K23419  SPINK4; serine protease inhibitor Kazal-type 4
       K23420  SPINK5; serine protease inhibitor Kazal-type 5
       K23603  SPINK6_7_9; serine protease inhibitor Kazal-type 6/7/9
       K23604  SPINK8; serine protease inhibitor Kazal-type 8
       K23606  SPINK10_11; serine protease inhibitor Kazal-type 10/11
       K19924  SPINK13; serine protease inhibitor Kazal-type 13
       K23613  SPINK14; serine protease inhibitor Kazal-type 14
       K23615  SPIK5; ovoinhibitor
       K23614  SPIK7; ovomucoid
       K04661  FST; follistatin
       K23912  FSTL1; follistatin-related protein 1
       K23913  FSTL3; follistatin-related protein 3
       K23914  FSTL4; follistatin-related protein 4
       K23915  FSTL5; follistatin-related protein 5
       K23607  TMEFF1; tomoregulin-1
       K23608  TMEFF2; tomoregulin-2
       K23620  AMBP; protein AMBP
       K15619  SPINT1; Kunitz-type protease inhibitor 1
       K23421  SPINT2; Kunitz-type protease inhibitor 2
       K23422  SPINT3; Kunitz-type protease inhibitor 3
       K23423  SPINT4; Kunitz-type protease inhibitor 4
       K03909  TFPI; tissue factor pathway inhibitor
       K23087  TFPI2; tissue factor pathway inhibitor 2
       K04520  APP; amyloid beta A4 protein
       K08117  APLP2; amyloid-like protein 2
       K23621  WFIKKN; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein
       K23622  EPPIN; eppin
       K23623  WFDC8; WAP four-disulfide core domain protein 8
       K23624  PAPLN; papilin
       K23619  COL28A; collagen type XXVIII alpha
       K03984  SERPINA1, AAT; alpha-1-antitrypsin
       K03913  SERPINA5, PCI; protein C inhibitor
       K20734  SERPINA7, TBG; thyroxine-binding globulin
       K09821  AGT, SERPINA8; angiotensinogen
       K04525  SERPINA; serpin A
       K23425  SERPINB1; leukocyte elastase inhibitor
       K19821  SERPINB2, PAI2; plasminogen activator inhibitor 2
       K10139  SERPINB5; serpin B5
       K13964  SERPINB7; serpin B7
       K13965  SERPINB8; serpin B8
       K13966  SERPINB11_12; serpin B11/12
       K13963  SERPINB; serpin B
       K03911  SERPINC1, AT3; antithrombin III
       K03912  SERPIND1, HCF2; heparin cofactor II
       K03982  SERPINE1, PAI1; plasminogen activator inhibitor 1
       K16643  SERPINE2; glia-derived nexin
       K23429  SERPINE3; serpin E3
       K19614  SERPINF1, PEDF; pigment epithelium-derived factor
       K03983  SERPINF2, AAP; alpha-2-antiplasmin
       K04001  SERPING1, C1INH; C1 inhibitor
       K09501  SERPINH1, HSP47; serpin peptidase inhibitor, clade H, member 1
       K23412  SERPINI1; neuroserpin
       K23430  SERPINI2; serpin I2
       K20698  NEC; necrotic
       K25943  K2L; Orthopoxvirus serine proteinase inhibitor 3
       K08276  eco; ecotin
       K23635  WFDC1; WAP four-disulfide core domain protein 1
       K23636  WFDC2; WAP four-disulfide core domain protein 2
       K23637  WFDC3; WAP four-disulfide core domain protein 3
       K23638  SLPI, WFDC4; antileukoproteinase
       K23639  WFDC5; WAP four-disulfide core domain protein 5
       K23640  WFDC6; WAP four-disulfide core domain protein 6
       K23641  WFDC12; WAP four-disulfide core domain protein 12
       K23642  PI3, WFDC14; elafin
       K23413  ANOS1, KAL1, WFDC19; anosmin-1
       K13907  CSTA_B; cystatin-A/B
       K13897  CST1; cystatin-SN
       K13898  CST2; cystatin-SA
       K13899  CST3; cystatin-C
       K13900  CST4; cystatin-S
       K13901  CST5; cystatin-D
       K13902  CST6; cystatin-M
       K13903  CST7; cystatin-F
       K13904  CST8; cystatin-8
       K13905  CST9; cystatin-9
       K13906  CST11; cystatin-11
       K03898  KNG, BK; kininogen
       K23409  AHSG, FETUA; alpha-2-HS-glycoprotein
       K23410  HRG; histidine-rich glycoprotein
       K23411  FETUB; fetuin-B
       K04281  CAST; calpastatin
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K23592  PAI3; protease A inhibitor 3
       K16451  TIMP1; metalloproteinase inhibitor 1
       K22583  TIMP2; metalloproteinase inhibitor 2
       K16866  TIMP3; metalloproteinase inhibitor 3
       K22584  TIMP4; metalloproteinase inhibitor 4
       K03910  A2M; alpha-2-macroglobulin
       K23589  PZP; pregnancy zone protein
       K06530  CD109; CD109 antigen
       K23593  A2ML; alpha-2-macroglobulin-like protein
       K06894  yfhM; alpha-2-macroglobulin
       K03990  C3; complement component 3
       K03989  C4; complement component 4
       K03994  C5; complement component 5
       K23594  LXN; latexin
       K23595  RARRES1; retinoic acid receptor responder protein 1
       K23596  PCSK1N; proSAAS
       K06910  PEBP, TFS1; phosphatidylethanolamine-binding protein
       K23597  sspC; staphostatin B
       K10786  PRG2, MBP; bone marrow proteoglycan
       K22244  REG4; regenerating islet-derived protein 4
       K23598  iseA; iseA protein
       K04087  hflC; modulator of FtsH protease HflC
       K04088  hflK; modulator of FtsH protease HflK
       K23599  SZL; secreted Xwnt8 inhibitor sizzled
       K02222  SFRP5; secreted frizzled-related protein 5
     01003 Glycosyltransferases [BR:ko01003]
     01005 Lipopolysaccharide biosynthesis proteins [BR:ko01005]
     01011 Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
     01004 Lipid biosynthesis proteins [BR:ko01004]
     01008 Polyketide biosynthesis proteins [BR:ko01008]
     01006 Prenyltransferases [BR:ko01006]
     01007 Amino acid related enzymes [BR:ko01007]
     00199 Cytochrome P450 [BR:ko00199]
     00194 Photosynthesis proteins [BR:ko00194]
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 22, 2024