KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
   Transcription
 
   Translation
 
   Folding, sorting and degradation
     03110 Chaperones and folding catalysts [BR:ko03110]
     03060 Protein export [PATH:ko03060]
     04141 Protein processing in endoplasmic reticulum [PATH:ko04141]
       K10956  SEC61A; protein transport protein SEC61 subunit alpha
       K09481  SEC61B, SBH2; protein transport protein SEC61 subunit beta
       K07342  SEC61G, SSS1, secE; protein transport protein SEC61 subunit gamma and related proteins
       K12275  SEC62; translocation protein SEC62
       K09540  SEC63; translocation protein SEC63
       K12666  OST1, RPN1; oligosaccharyltransferase complex subunit alpha (ribophorin I)
       K12667  SWP1, RPN2; oligosaccharyltransferase complex subunit delta (ribophorin II)
       K12668  OST2, DAD1; oligosaccharyltransferase complex subunit epsilon
       K12669  OST3, OST6; oligosaccharyltransferase complex subunit gamma
       K12670  WBP1; oligosaccharyltransferase complex subunit beta
       K00730  OST4; oligosaccharyl transferase complex subunit OST4
       K12691  OST5; oligosaccharyl transferase complex subunit OST5
       K07151  STT3; dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18]
       K01228  GCS1; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]
       K13999  CKAP4, CLIMP63; cytoskeleton-associated protein 4
       K14000  RRBP1; ribosome-binding protein 1
       K14001  SIL1, SLS1; nucleotide exchange factor SIL1
       K09486  HYOU1; hypoxia up-regulated 1
       K09490  HSPA5, BIP; heat shock 70kDa protein 5
       K09517  DNAJB11; DnaJ homolog subfamily B member 11
       K09521  DNAJC1; DnaJ homolog subfamily C member 1
       K09523  DNAJC3; DnaJ homolog subfamily C member 3
       K09530  DNAJC10; DnaJ homolog subfamily C member 10
       K14002  SCJ1; DnaJ-related protein SCJ1
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K05546  GANAB; alpha 1,3-glucosidase [EC:3.2.1.84]
       K08288  PRKCSH; protein kinase C substrate 80K-H
       K08054  CANX; calnexin
       K08056  PDIA3, GRP58; protein disulfide isomerase family A, member 3 [EC:5.3.4.1]
       K08057  CALR; calreticulin
       K01230  MAN1; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
       K10082  LMAN2, VIP36; lectin, mannose-binding 2
       K10080  LMAN1, ERGIC53; lectin, mannose-binding 1
       K10081  LMAN1L, ERGL; lectin, mannose-binding 1-like
       K14003  PREB, SEC12; prolactin regulatory element-binding protein
       K07953  SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
       K14004  SEC13; protein transport protein SEC13
       K14005  SEC31; protein transport protein SEC31
       K14006  SEC23; protein transport protein SEC23
       K14007  SEC24; protein transport protein SEC24
       K11718  HUGT; UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-]
       K10084  EDEM1; ER degradation enhancer, mannosidase alpha-like 1
       K10085  EDEM2; ER degradation enhancer, mannosidase alpha-like 2
       K10086  EDEM3; ER degradation enhancer, mannosidase alpha-like 3
       K09580  PDIA1, P4HB; protein disulfide-isomerase A1 [EC:5.3.4.1]
       K09582  PDIA4, ERP72; protein disulfide-isomerase A4 [EC:5.3.4.1]
       K09584  PDIA6, TXNDC7; protein disulfide-isomerase A6 [EC:5.3.4.1]
       K13996  EPS1; protein disulfide-isomerase [EC:5.3.4.1]
       K09586  ERP29; endoplasmic reticulum protein 29
       K13984  TXNDC5, ERP46; thioredoxin domain-containing protein 5
       K10950  ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
       K10976  ERO1LB; ERO1-like protein beta [EC:1.8.4.-]
       K10088  OS9; protein OS-9
       K14008  ERLEC1, XTP3B; endoplasmic reticulum lectin 1
       K13249  SSR1; translocon-associated protein subunit alpha
       K13250  SSR2; translocon-associated protein subunit beta
       K13251  SSR3; translocon-associated protein subunit gamma
       K04571  SSR4; translocon-associated protein subunit delta
       K14009  BCAP31, BAP31; B-cell receptor-associated protein 31
       K14010  TRAM1; translocating chain-associated membrane protein 1
       K11519  DERL1; Derlin-1
       K13989  DERL2_3; Derlin-2/3
       K14011  UBXN6, UBXD1; UBX domain-containing protein 6
       K14012  SHP1, UBX1, NSFL1C; UBX domain-containing protein 1
       K14013  UBX2, SEL1; UBX domain-containing protein 2
       K14014  SVIP; small VCP/p97-interacting protein
       K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
       K14015  NPLOC4, NPL4; nuclear protein localization protein 4 homolog
       K14016  UFD1; ubiquitin fusion degradation protein 1
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K09502  DNAJA1; DnaJ homolog subfamily A member 1
       K09503  DNAJA2; DnaJ homolog subfamily A member 2
       K09507  DNAJB1; DnaJ homolog subfamily B member 1
       K09508  DNAJB2; DnaJ homolog subfamily B member 2
       K09518  DNAJB12; DnaJ homolog subfamily B member 12
       K09525  DNAJC5; DnaJ homolog subfamily C member 5
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09485  HSP110; heat shock protein 110kDa
       K09555  BAG1; BCL2-associated athanogene 1
       K09556  BAG2; BCL2-associated athanogene 2
       K09562  HSPBP1; hsp70-interacting protein
       K14017  SNL1; HSP70 co-chaperone SNL1
       K09541  CRYAA; crystallin, alpha A
       K09542  CRYAB; crystallin, alpha B
       K13993  HSP20; HSP20 family protein
       K13719  OTU1, YOD1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
       K14018  PLAA, DOA1, UFD3; phospholipase A-2-activating protein
       K10839  RAD23, HR23; UV excision repair protein RAD23
       K04523  UBQLN, DSK2; ubiquilin
       K01456  E3.5.1.52, NGLY1, PNG1; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]
       K11863  ATXN3, MJD; Ataxin-3 [EC:3.4.22.-]
       K10597  UBE4B, UFD2; ubiquitin conjugation factor E4 B [EC:6.3.2.19]
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K14019  PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K02161  BCL2; apoptosis regulator BCL-2
       K09054  ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K14020  WFS1; wolfamin
       K08653  MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
       K07765  MBTPS2; S2P endopeptidase [EC:3.4.24.85]
       K09027  XBP1; X box-binding protein 1
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K03173  TRAF2; TNF receptor-associated factor 2
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K10661  MARCH6, DOA10; E3 ubiquitin-protein ligase MARCH6 [EC:6.3.2.19]
       K10578  UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:6.3.2.19]
       K04554  UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19]
       K10575  UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19]
       K04555  UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19]
       K14022  CUE1, KIS4; coupling of ubiquitin conjugation to ER degradation protein 1
       K14023  HRD3; ERAD-associated E3 ubiquitin-protein ligase component HRD3
       K10601  SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19]
       K14024  USA1; U1 SNP1-associating protein 1
       K10666  RNF5; E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19]
       K14025  SELS, VIMP; selenoprotein S
       K14026  SEL1, SEL1L; SEL1 protein
       K14027  HERPUD1, HERP; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
       K10636  AMFR, GP78; autocrine motility factor receptor [EC:6.3.2.19]
       K09561  STUB1, CHIP; STIP1 homology and U-box containing protein 1 [EC:6.3.2.19]
       K06689  UBE2D_E, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]
       K04556  PARK2; parkin [EC:6.3.2.19]
       K03868  RBX1, ROC1; RING-box protein 1
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K10099  FBXO2, NFB42; F-box protein 2
       K10100  FBXO6; F-box protein 6
     04130 SNARE interactions in vesicular transport [PATH:ko04130]
     04131 SNAREs [BR:ko04131]
     04120 Ubiquitin mediated proteolysis [PATH:ko04120]
     04121 Ubiquitin system [BR:ko04121]
     04122 Sulfur relay system [PATH:ko04122]
     03050 Proteasome [PATH:ko03050]
     03051 Proteasome [BR:ko03051]
     03018 RNA degradation [PATH:ko03018]
 
   Replication and repair
 
   RNA family
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K05315  CACNA1N; voltage-dependent calcium channel alpha 1, invertebrate
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K05316  CACNA2DN; voltage-dependent calcium channel alpha-2/delta, invertebrate
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K05317  CACNBN; voltage-dependent calcium channel beta, invertebrate
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04370  MP1, MAP2K1IP1; mitogen-activated protein kinase kinase 1 interacting protein 1
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04377  MYC; Myc proto-oncogene protein
       K04378  SRF; serum response factor
       K04379  FOS; proto-oncogene protein c-fos
       K04380  MAPT, TAU; microtubule-associated protein tau
       K04381  STMN1; stathmin
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04391  CD14; CD14 antigen
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03173  TRAF2; TNF receptor-associated factor 2
       K02308  DAXX; death-associated protein 6
       K03175  TRAF6; TNF receptor-associated factor 6
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04405  ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
       K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
       K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
       K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K04411  STK4, MST1; serine/threonine kinase 4
       K04412  STK3, MST2; serine/threonine kinase 3
       K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
       K04435  MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
       K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
       K04437  FLNA; filamin
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04439  ARRB; beta-arrestin
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  MSK2, RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04451  TP53, P53; tumor protein p53
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K04453  MAX; Max protein
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04455  HSPB1; heat shock protein beta-1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K09253  RELB; transcription factor RelB
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
       K07362  LAT; linker for activation of T cells
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K07371  BLNK; B-cell linker protein
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07367  CARD11; caspase recruitment domain-containing protein 11
       K07368  BCL10; B-cell CLL/lymphoma 10
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2
       K09849  TRAF5; TNF receptor-associated factor 5
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K10652  TRIM25, EFP; tripartite motif-containing protein 25 [EC:6.3.2.19]
       K05399  LBP; lipopolysaccharide-binding protein
       K04391  CD14; CD14 antigen
       K10160  TLR4; toll-like receptor 4
       K05400  LY96, MD-2; lymphocyte antigen 96
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05842  TRIF; toll-like receptor adapter molecule 1
       K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K03174  TRAF3; TNF receptor-associated factor 3
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K05477  TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K05476  TNFSF13B, TNFSF20; tumor necrosis factor ligand superfamily member 13B
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K10130  LRDD, PIDD; leucine-rich repeats and death domain-containing protein
       K16072  ERC1; ELKS/RAB6-interacting/CAST family member 1
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K03172  TRAF1; TNF receptor-associated factor 1
       K02162  BCL2A1; hematopoietic BCL2-related protein A1
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K10030  IL8, CXCL8; interleukin 8
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K12964  CCL4; C-C motif chemokine 4
       K06527  VCAM1; vascular cell adhesion molecule 1
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K09253  RELB; transcription factor RelB
       K16595  CCL13; C-C motif chemokine 13
       K05512  CCL19, ELC; C-C motif chemokine 19
       K16062  CCL21, SLC; C-C motif chemokine 21
       K10031  CXCL12; C-X-C motif chemokine 12
       K06490  ICAM1; intercellular adhesion molecule 1
     04668 TNF signaling pathway [PATH:ko04668]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K09558  BAG4; BCL2-associated athanogene 4
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2
       K09849  TRAF5; TNF receptor-associated factor 5
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K05632  AIP4, ITCH; atrophin-1 interacting protein 4 [EC:6.3.2.19]
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K10048  CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  MSK2, RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
       K08849  MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
       K15637  PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
       K17065  DNM1L; dynamin 1-like protein [EC:3.6.5.5]
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12499  CCL5; C-C motif chemokine 5
       K14625  CCL20; C-C motif chemokine 20
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K05508  CX3CL1, NTT; C-X3-C motif chemokine 1
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K05173  IL18R1, IL1RRP; interleukin 18 receptor 1
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K05433  IL15; interleukin 15
       K05419  LIF; leukemia inhibitory factor
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K09258  BCL3; B-cell CLL/lymphoma protein 3
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19]
       K03172  TRAF1; TNF receptor-associated factor 1
       K17072  IFI47; interferon gamma inducible protein 47
       K04379  FOS; proto-oncogene protein c-fos
       K09028  JUNB; transcription factor jun-B
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K07763  MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
       K16366  EDN1; endothelin-1
       K10165  NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
       K06490  ICAM1; intercellular adhesion molecule 1
       K06494  SELE; selectin, endothelial cell
       K06527  VCAM1; vascular cell adhesion molecule 1
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K03174  TRAF3; TNF receptor-associated factor 3
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05629  AIP1; atrophin-1 interacting protein 1
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04721  TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K02373  FADD; FAS-associated death domain protein
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K04396  CASP6; caspase 6 [EC:3.4.22.59]
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04726  BID; BH3 interacting domain death agonist
       K02161  BCL2; apoptosis regulator BCL-2
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02310  DFFA, DFF45; DNA fragmentation factor, 45 kD, alpha subunit
       K02311  DFFB, DFF40; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
       K04727  PDCD8, AIF; programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-]
       K01173  ENDOG; endonuclease G, mitochondrial
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K03173  TRAF2; TNF receptor-associated factor 2
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
       K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02582  NGFB; nerve growth factor, beta
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04736  IL3; interleukin 3
       K04737  IL3RA; interleukin 3 receptor alpha
       K04738  CSF2RB, IL3RB; cytokine receptor common subunit beta
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02158  BAD; BCL2-antagonist of cell death
       K02159  BAX; apoptosis regulator BAX
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
     04115 p53 signaling pathway [PATH:ko04115]
 
   Cell communication
 
 Organismal Systems
 
   Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K12649  DHX58, LGP2; ATP-dependent RNA helicase DHX58 [EC:3.6.3.14]
       K03174  TRAF3; TNF receptor-associated factor 3
       K12650  TANK; TRAF family member-associated NF-kappa-B activator
       K12651  AZI2; 5-azacytidine-induced protein 2
       K12652  TBKBP1; TANK-binding kinase 1-binding protein
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05440  IFNW1; interferon, omega 1
       K05442  IFNT1; interferon, tau-1
       K05441  IFNK; interferon, kappa
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02373  FADD; FAS-associated death domain protein
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K03173  TRAF2; TNF receptor-associated factor 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K03175  TRAF6; TNF receptor-associated factor 6
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K10030  IL8, CXCL8; interleukin 8
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K10652  TRIM25, EFP; tripartite motif-containing protein 25 [EC:6.3.2.19]
       K08601  CYLD, USLP2; ubiquitin thioesterase CYLD [EC:3.1.2.15]
       K12170  RNF125; E3 ubiquitin-protein ligase RNF125 [EC:6.3.2.19]
       K12159  ISG15; ubiquitin cross-reactive protein
       K08339  ATG5; autophagy-related protein 5
       K08336  ATG12; ubiquitin-like protein ATG12
       K12653  NLRX1; NLR family member X1
       K12654  TMEM173, MITA; transmembrane protein 173
       K12655  OTUD5, DUBA; OTU domain-containing protein 5 [EC:3.4.19.12]
       K12656  SIKE; suppressor of IKK-epsilon
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
       K09578  PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
       K00863  E2.7.1.29, DAK1, DAK2; dihydroxyacetone kinase [EC:2.7.1.29]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04662 B cell receptor signaling pathway [PATH:ko04662]
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K03173  TRAF2; TNF receptor-associated factor 2
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K06259  CD36; CD36 antigen
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K05228  POMC; proopiomelanocortin
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K05231  AGRP; agouti related protein
       K05232  NPY; neuropeptide Y
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
     04320 Dorso-ventral axis formation [PATH:ko04320]
     04360 Axon guidance [PATH:ko04360]
     04380 Osteoclast differentiation [PATH:ko04380]
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11220  STAT1; signal transducer and activator of transcription 1
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K05148  TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
       K03173  TRAF2; TNF receptor-associated factor 2
       K03175  TRAF6; TNF receptor-associated factor 6
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K05415  IFNB; interferon beta
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K09029  FOSB; protein FosB
       K09030  FOSL2; fos-like antigen 2
       K04502  FOSL1; fos-like antigen 1
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K09028  JUNB; transcription factor jun-B
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K08008  NOX, GP91; NADPH oxidase
       K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
       K08010  NCF2, P67PHOX; neutrophil cytosolic factor 2
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K08012  NCF4, P40PHOX; neutrophil cytosolic factor 4
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K07364  TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
       K14377  OSCAR; osteoclast-associated immunoglobulin-like receptor
       K06512  LILR; leukocyte immunoglobulin-like receptor
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
       K16824  FCGR2C, CD32; low affinity immunoglobulin gamma Fc region receptor II-c
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
       K14378  TREM2; triggering receptor expressed on myeloid cells 2
       K06551  SIRPA_B1_G; signal-regulatory protein alpha/beta1/gamma
       K07992  TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K07371  BLNK; B-cell linker protein
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09438  SPI1; transcription factor PU.1
       K09455  MITF; microphthalmia-associated transcription factor
       K01371  CTSK; cathepsin K [EC:3.4.22.38]
       K14379  ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
       K04576  CALCR; calcitonin receptor
       K06493  ITGB3; integrin beta 3
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K14380  FHL2; four and a half LIM domains protein 2
       K08601  CYLD, USLP2; ubiquitin thioesterase CYLD [EC:3.1.2.15]
       K14381  SQSTM1; sequestosome 1
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K02353  DVL; segment polarity protein dishevelled
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator BCL-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04358  FGF; fibroblast growth factor
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04513  RHOA; Ras homolog gene family, member A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05405  IL6; interleukin 6
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04496  CTBP; C-terminal binding protein
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K02159  BAX; apoptosis regulator BAX
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03868  RBX1, ROC1; RING-box protein 1
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06227  COS2; costal 2
       K06228  FU; fused [EC:2.7.11.1]
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K04662  BMP2_4; bone morphogenetic protein 2/4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  NR3C4, AR; androgen receptor
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K10610  DDB1; DNA damage-binding protein 1
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08665  HPN; hepsin (transmembrane protease, serine 1) [EC:3.4.21.-]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04735  RELA; transcription factor p65
       K09254  REL; c-Rel proto-oncogene protein
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04451  TP53, P53; tumor protein p53
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K12496  EGR2; early growth response protein 2
       K12497  EGR3; early growth response protein 3
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K15413  SP100; nuclear autoantigen Sp-100
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K11252  H2B; histone H2B
       K11254  H4; histone H4
       K02159  BAX; apoptosis regulator BAX
       K04364  GRB2; growth factor receptor-binding protein 2
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K06053  RBPSUH, RBPJK; recombining binding protein suppressor of hairless
       K06063  SNW1, SKIIP, SKIP; SNW domain-containing protein 1
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K03136  TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
       K03137  TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
       K15979  SND1; staphylococcal nuclease domain-containing protein 1
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K03124  TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06627  CCNA; cyclin A
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K16174  MRPS18B, MRPS18-2; small subunit ribosomal protein S18b, mitochondrial
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K10587  UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:6.3.2.19]
       K12076  DLG1; disks large protein 1
       K16175  SCRIB; protein scribble
       K05760  PXN; paxillin
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K05411  IRF3; interferon regulatory factor 3
       K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2
       K06618  RB1; retinoblastoma-associated protein
       K04681  RBL1; retinoblastoma-like protein 1
       K16332  RBL2; retinoblastoma-like protein 2
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K10691  UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19]
       K04448  JUN; transcription factor AP-1
       K11643  CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K11404  HDAC3; histone deacetylase 3 [EC:3.5.1.98]
       K11406  HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
       K11407  HDAC6_10; histone deacetylase 6/10 [EC:3.5.1.98]
       K11408  HDAC7; histone deacetylase 7 [EC:3.5.1.98]
       K11405  HDAC8; histone deacetylase 8 [EC:3.5.1.98]
       K11409  HDAC9; histone deacetylase 9 [EC:3.5.1.98]
       K11418  HDAC11; histone deacetylase 11 [EC:3.5.1.98]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K09504  DNAJA3; DnaJ homolog subfamily A member 3
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K03122  TFIIA1, GTF2A1, TOA1; transcription initiation factor TFIIA large subunit
       K03123  TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit
       K04378  SRF; serum response factor
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04513  RHOA; Ras homolog gene family, member A
       K05768  GSN; gelsolin
       K05699  ACTN; actinin alpha
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K09447  IRF7; interferon regulatory factor 7
       K05060  IL6ST, GP130; interleukin 6 signal transducer
       K04180  CCR5; C-C chemokine receptor type 5
       K04183  CCR8; C-C chemokine receptor type 8
       K04178  CCR3; C-C chemokine receptor type 3
       K04179  CCR4; C-C chemokine receptor type 4
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02158  BAD; BCL2-antagonist of cell death
       K10131  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       K03990  C3; complement component 3
       K06751  MHC1; major histocompatibility complex, class I
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K04451  TP53, P53; tumor protein p53
       K02161  BCL2; apoptosis regulator BCL-2
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04377  MYC; Myc proto-oncogene protein
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K04503  CCND1; cyclin D1
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
     04940 Type I diabetes mellitus [PATH:ko04940]
     04930 Type II diabetes mellitus [PATH:ko04930]
     04950 Maturity onset diabetes of the young [PATH:ko04950]
     04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:ko04932]
       K05405  IL6; interleukin 6
       K05055  IL6R; interleukin 6 receptor
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K08536  NR1H3, LXRA; liver X receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K09113  MLX; MAX-like protein X
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K05632  AIP4, ITCH; atrophin-1 interacting protein 4 [EC:6.3.2.19]
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K03173  TRAF2; TNF receptor-associated factor 2
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04448  JUN; transcription factor AP-1
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K09027  XBP1; X box-binding protein 1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K10030  IL8, CXCL8; interleukin 8
       K13375  TGFB1; transforming growth factor beta-1
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K02159  BAX; apoptosis regulator BAX
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
       K12473  LDLR; low-density lipoprotein receptor
       K13885  SCARB1; scavenger receptor class B, member 1
       K06508  CD81, TAPA1, TSPAN28; CD81 antigen
       K06087  CLDN; claudin
       K06088  OCLN; occludin
       K14216  OAS; 2'-5'-oligoadenylate synthetase
       K01165  RNASEL; ribonuclease L
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K03174  TRAF3; TNF receptor-associated factor 3
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K05415  IFNB; interferon beta
       K05401  TLR3; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K03175  TRAF6; TNF receptor-associated factor 6
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K09444  IRF1; interferon regulatory factor 1
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K10030  IL8, CXCL8; interleukin 8
       K04692  STAT3; signal transducer and activator of transcription 3
       K14217  IFIT1; interferon-induced protein with tetratricopeptide repeats 1
       K03250  EIF3E, INT6; translation initiation factor 3 subunit E
       K05414  IFNA; interferon alpha
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K04706  PIAS1; E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-]
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02158  BAD; BCL2-antagonist of cell death
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03173  TRAF2; TNF receptor-associated factor 2
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K06698  PSME3; proteasome activator subunit 3 (PA28 gamma)
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08536  NR1H3, LXRA; liver X receptor alpha
     05168 Herpes simplex infection [PATH:ko05168]
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K05477  TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
       K05152  TNFRSF14, HVEM; tumor necrosis factor receptor superfamily member 14
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K06081  PVRL1; poliovirus receptor-related protein 1
       K06531  PVRL2; poliovirus receptor-related protein 2
       K15411  PILRA; paired immunoglobulin-like type 2 receptor alpha
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K10159  TLR2; toll-like receptor 2
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K03175  TRAF6; TNF receptor-associated factor 6
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K10161  TLR9; toll-like receptor 9
       K05401  TLR3; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12499  CCL5; C-C motif chemokine 5
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05433  IL15; interleukin 15
       K05414  IFNA; interferon alpha
       K14217  IFIT1; interferon-induced protein with tetratricopeptide repeats 1
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K14216  OAS; 2'-5'-oligoadenylate synthetase
       K01165  RNASEL; ribonuclease L
       K03990  C3; complement component 3
       K03994  C5; complement component 5
       K15412  CFP; complement factor properdin
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K02207  UBE2R, UBC3, CDC34; ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19]
       K03347  CUL1, CDC53; cullin 1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K15410  EEF1D; elongation factor 1-delta
       K14840  NOP53, GLTSCR2; nucleolar protein 53
       K11674  MCRS1, INO80Q; microspherule protein 1
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K15409  SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
       K12890  SFRS1_9; splicing factor, arginine/serine-rich 1/9
       K12891  SFRS2; splicing factor, arginine/serine-rich 2
       K12892  SFRS3; splicing factor, arginine/serine-rich 3
       K12893  SFRS4_5_6; splicing factor, arginine/serine-rich 4/5/6
       K12896  SFRS7; splicing factor, arginine/serine-rich 7
       K10054  PML, TRIM19; probable transcription factor PML
       K15413  SP100; nuclear autoantigen Sp-100
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04451  TP53, P53; tumor protein p53
       K02308  DAXX; death-associated protein 6
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K14966  HCFC; host cell factor
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K03133  TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
       K03131  TAF6; transcription initiation factor TFIID subunit 6
       K03130  TAF5; transcription initiation factor TFIID subunit 5
       K03129  TAF4; transcription initiation factor TFIID subunit 4
       K14650  TAF3; transcription initiation factor TFIID subunit 3
       K03127  TAF13; transcription initiation factor TFIID subunit 13
       K03134  TAF10; transcription initiation factor TFIID subunit 10
       K15129  MED8; mediator of RNA polymerase II transcription subunit 8
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
       K11299  HMGN1; high-mobility group nucleosome-binding domain-containing protein 1
       K12881  THOC4, ALY; THO complex subunit 4
       K14284  NXF1_2, TAP; nuclear RNA export factor 1/2
       K15414  C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K06752  MHC2; major histocompatibility complex, class II
       K06505  CD74, DHLAG; CD74 antigen
       K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
       K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
       K06751  MHC1; major histocompatibility complex, class I
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08738  CYC; cytochrome c
       K02296  ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1
       K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
       K02633  PER; period circadian protein
     05169 Epstein-Barr virus infection [PATH:ko05169]
       K04012  CR2, CD21; complement receptor type 2
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
       K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
       K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
       K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
       K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
       K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
       K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
       K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
       K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
       K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
       K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
       K14290  XPO1, CRM1; exportin-1
       K07936  RAN; GTP-binding nuclear protein Ran
       K14317  NUP214, CAN; nuclear pore complex protein Nup214
       K06751  MHC1; major histocompatibility complex, class I
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K06477  SPN, CD43; sialophorin
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K15978  AKAP8L, HA95; A-kinase anchor protein 8-like protein
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04455  HSPB1; heat shock protein beta-1
       K09543  HSPB2; heat shock protein beta-2
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K03124  TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
       K15979  SND1; staphylococcal nuclease domain-containing protein 1
       K03136  TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
       K03137  TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
       K11406  HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
       K06063  SNW1, SKIIP, SKIP; SNW domain-containing protein 1
       K06065  NCOR2, SMRT; nuclear receptor co-repressor 2
       K06053  RBPSUH, RBPJK; recombining binding protein suppressor of hairless
       K09438  SPI1; transcription factor PU.1
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K13784  PTMA; prothymosin alpha
       K06468  FCER2, CD23; Fc receptor, IgE, low affinity II
       K08891  FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
       K04377  MYC; Myc proto-oncogene protein
       K04451  TP53, P53; tumor protein p53
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K03061  PSMC2, RPT1; 26S proteasome regulatory subunit T1
       K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2
       K03063  PSMC4, RPT3; 26S proteasome regulatory subunit T3
       K03064  PSMC6, RPT4; 26S proteasome regulatory subunit T4
       K03065  PSMC3, RPT5; 26S proteasome regulatory subunit T5
       K03066  PSMC5, RPT6; 26S proteasome regulatory subunit T6
       K03028  PSMD2, RPN1; 26S proteasome regulatory subunit N1
       K03032  PSMD1, RPN2; 26S proteasome regulatory subunit N2
       K03033  PSMD3, RPN3; 26S proteasome regulatory subunit N3
       K03035  PSMD12, RPN5; 26S proteasome regulatory subunit N5
       K03036  PSMD11, RPN6; 26S proteasome regulatory subunit N6
       K03037  PSMD6, RPN7; 26S proteasome regulatory subunit N7
       K03038  PSMD7, RPN8; 26S proteasome regulatory subunit N8
       K03039  PSMD13, RPN9; 26S proteasome regulatory subunit N9
       K03029  PSMD4, RPN10; 26S proteasome regulatory subunit N10
       K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
       K03031  PSMD8, RPN12; 26S proteasome regulatory subunit N12
       K06691  RPN13; 26S proteasome regulatory subunit N13
       K10881  SHFM1, DSS1; 26 proteasome complex subunit DSS1
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06627  CCNA; cyclin A
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K01510  ENTPD1_3_8; apyrase [EC:3.6.1.5]
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K06256  CD44; CD44 antigen
       K05718  ITGAL; integrin alpha L
       K06492  CD58, LFA3; CD58 antigen
       K06490  ICAM1; intercellular adhesion molecule 1
       K07606  VIM; vimentin
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19]
       K02161  BCL2; apoptosis regulator BCL-2
       K06856  IGH; immunoglobulin heavy chain
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06465  CD19; CD19 antigen
       K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K04687  IFNG; interferon gamma
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K05443  IL10, CSIF; interleukin 10
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 26, 2014