 Metabolism
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 Genetic Information Processing
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Transcription
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Translation
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03010 Ribosome [PATH:ko03010]
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 03011 Ribosome [BR:ko03011]
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03016 Transfer RNA biogenesis [BR:ko03016]
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00970 Aminoacyl-tRNA biosynthesis [PATH:ko00970]
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03013 RNA transport [PATH:ko03013]
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K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
K14522 POP3; ribonuclease P/MRP protein subunit POP3 [EC:3.1.26.5]
K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
K03538 POP4, RPP29; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
K14524 POP6; ribonuclease P/MRP protein subunit POP6 [EC:3.1.26.5]
K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
K14526 POP7, RPP2; ribonuclease P/MRP protein subunit POP7 [EC:3.1.26.5]
K14527 RPP20, POP7; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
K14528 POP8; ribonuclease P/MRP protein subunit POP8 [EC:3.1.26.5]
K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
K03539 RPP1, RPP30; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
K03540 RPR2, RPP21; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
K00784 rnz; ribonuclease Z [EC:3.1.26.11]
K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
K07936 RAN; GTP-binding nuclear protein Ran
K14288 XPOT; exportin-T
K14289 XPO5; exportin-5
K03231 EEF1A; elongation factor 1-alpha
K14290 XPO1, CRM1; exportin-1
K14291 PHAX; phosphorylated adapter RNA export protein
K12882 NCBP1, CBP80; nuclear cap-binding protein subunit 1
K12883 NCBP2, CBP20; nuclear cap-binding protein subunit 2
K05019 CLNS1A; chloride channel, nucleotide-sensitive, 1A
K02516 PRMT5, HSL7; protein arginine N-methyltransferase 5 [EC:2.1.1.125]
K14292 TGS1; trimethylguanosine synthase [EC:2.1.1.-]
K14293 KPNB1; importin subunit beta-1
K13151 SNUPN, RNUT1; snurportin-1
K07562 NMD3; nonsense-mediated mRNA decay protein 3
K14294 WIBG, PYM; partner of Y14 and mago
K09291 TPR; nucleoprotein TPR
K14295 NUP50, NPAP60; nuclear pore complex protein Nup50
K14296 NUP153; nuclear pore complex protein Nup153
K03345 SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
K14297 NUP98, ADAR2; nuclear pore complex protein Nup98-Nup96
K14298 RAE1; mRNA export factor
K14004 SEC13; protein transport protein SEC13
K14299 SEH1; nucleoporin SEH1
K14300 NUP133; nuclear pore complex protein Nup133
K14301 NUP107; nuclear pore complex protein Nup107
K14302 NUP37; nuclear pore complex protein Nup37
K14303 NUP160; nuclear pore complex protein Nup160
K14304 NUP85; nuclear pore complex protein Nup85
K14305 NUP43; nuclear pore complex protein Nup43
K14306 NUP62; nuclear pore complex protein Nup62
K14307 NUPL1; nucleoporin p58/p45
K14308 NUP54; nuclear pore complex protein Nup54
K14309 NUP93; nuclear pore complex protein Nup93
K14310 NUP205; nuclear pore complex protein Nup205
K14311 NUP188; nuclear pore complex protein Nup188
K14312 NUP155; nuclear pore complex protein Nup155
K14313 NUP35, NUP53; nuclear pore complex protein Nup53
K14314 NUP210, GP210; nuclear pore complex protein Nup210
K14315 NDC1, TMEM48; nucleoporin NDC1
K14316 POM121, NUP121; nuclear pore complex protein Nup121
K14317 NUP214, CAN; nuclear pore complex protein Nup214
K14318 NUP88; nuclear pore complex protein Nup88
K12172 RANBP2, NUP358; E3 SUMO-protein ligase RanBP2
K14319 RANGAP1; Ran GTPase-activating protein 1
K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
K12160 SUMO, SMT3; small ubiquitin-related modifier
K14320 AAAS; aladin
K14321 NUPL2, CG1; nucleoporin-like protein 2
K13129 SMN; survival motor neuron protein
K13130 SIP1, GEMIN2; survival of motor neuron protein-interacting protein 1
K13131 DDX20, GEMIN3; ATP-dependent RNA helicase DDX20 [EC:3.6.4.13]
K13132 GEMIN4; gem associated protein 4
K13133 GEMIN5; gem associated protein 5
K13134 GEMIN6, SIP2; gem associated protein 6
K13135 GEMIN7, SIP3; gem associated protein 7
K13136 GEMIN8; gem associated protein 8
K13137 STRAP, UNRIP; serine-threonine kinase receptor-associated protein
K03245 EIF3J; translation initiation factor 3 subunit J
K03246 EIF3I; translation initiation factor 3 subunit I
K03247 EIF3H; translation initiation factor 3 subunit H
K03248 EIF3G; translation initiation factor 3 subunit G
K03249 EIF3F; translation initiation factor 3 subunit F
K03250 EIF3E, INT6; translation initiation factor 3 subunit E
K03251 EIF3D; translation initiation factor 3 subunit D
K03252 EIF3C; translation initiation factor 3 subunit C
K03253 EIF3B; translation initiation factor 3 subunit B
K03254 EIF3A; translation initiation factor 3 subunit A
K03236 EIF1A; translation initiation factor 1A
K03113 EIF1, SUI1; translation initiation factor 1
K03262 EIF5; translation initiation factor 5
K03237 EIF2S1; translation initiation factor 2 subunit 1
K03238 EIF2S2; translation initiation factor 2 subunit 2
K03242 EIF2S3; translation initiation factor 2 subunit 3
K03239 EIF2B1; translation initiation factor eIF-2B subunit alpha
K03754 EIF2B2; translation initiation factor eIF-2B subunit beta
K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
K03241 EIF2B3; translation initiation factor eIF-2B subunit gamma
K03240 EIF2B5; translation initiation factor eIF-2B subunit epsilon
K03243 EIF5B; translation initiation factor 5B
K03260 EIF4G; translation initiation factor 4G
K03259 EIF4E; translation initiation factor 4E
K03257 EIF4A; translation initiation factor 4A
K03258 EIF4B; translation initiation factor 4B
K13126 PABPC; polyadenylate-binding protein
K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K14283 TACC3, maskin; transforming acidic coiled-coil-containing protein 3
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K15516 FMR; fragile X mental retardation protein
K12876 RBM8A, Y14; RNA-binding protein 8A
K12877 MAGOH; protein mago nashi
K14323 CASC3, MLN51; protein CASC3
K13025 EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
K14324 SAP18; histone deacetylase complex subunit SAP18
K13114 PNN; pinin
K12875 ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
K14325 RNPS1; RNA-binding protein with serine-rich domain 1
K12881 THOC4, ALY; THO complex subunit 4
K12812 UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
K12878 THOC1; THO complex subunit 1
K12879 THOC2; THO complex subunit 2
K13174 THOC5; THO complex subunit 5
K13175 THOC6; THO complex subunit 6
K13176 THOC7; THO complex subunit 7
K12880 THOC3; THO complex subunit 3
K13171 SRRM1, SRM160; serine/arginine repetitive matrix protein 1
K14284 NXF1_2, TAP; nuclear RNA export factor 1/2
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K14543 MTR2; mRNA transport regulator MTR2
K14326 UPF1, RENT1; regulator of nonsense transcripts 1 [EC:3.6.4.-]
K14327 UPF2, RENT2; regulator of nonsense transcripts 2
K14328 UPF3, RENT3; regulator of nonsense transcripts 3
K14276 U1snRNA; U1 spliceosomal RNA
K14277 U2snRNA; U2 spliceosomal RNA
K14278 U4snRNA; U4 spliceosomal RNA
K14279 U5snRNA; U5 spliceosomal RNA
K14280 U6snRNA; U6 spliceosomal RNA
K14483 U3snoRNA, snR17; U3 small nucleolar RNA
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03015 mRNA surveillance pathway [PATH:ko03015]
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03008 Ribosome biogenesis in eukaryotes [PATH:ko03008]
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03009 Ribosome biogenesis [BR:ko03009]
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03012 Translation factors [BR:ko03012]
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Folding, sorting and degradation
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Replication and repair
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RNA family
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Environmental Information Processing
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Membrane transport
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Signal transduction
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02020 Two-component system [PATH:ko02020]
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02022 Two-component system [BR:ko02022]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway -fly [PATH:ko04391]
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04370 VEGF signaling pathway [PATH:ko04370]
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04630 Jak-STAT signaling pathway [PATH:ko04630]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K04692 STAT3; signal transducer and activator of transcription 3
K10160 TLR4; toll-like receptor 4
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K04527 INSR; insulin receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05083 ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03868 RBX1, ROC1; RING-box protein 1
K03872 TCEB1; transcription elongation factor B, polypeptide 1
K03873 TCEB2; transcription elongation factor B, polypeptide 2
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.-]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K08008 NOX, GP91; NADPH oxidase
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K16451 TIMP1; metallopeptidase inhibitor 1
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05437 EPO; erythropoietin
K14736 TF; transferrin
K06503 TFRC, CD71; transferrin receptor
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K03982 SERPINE1, PAI1; plasminogen activator inhibitor-1
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05121 TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K16366 EDN1; endothelin-1
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K12334 NPPA; natriuretic peptide A
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00844 HK; hexokinase [EC:2.7.1.1]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K01689 ENO, eno; enolase [EC:4.2.1.11]
K01103 PFKFB; 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
K02161 BCL2; apoptosis regulator BCL-2
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; nerve growth factor receptor (TNFR superfamily member 16)
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; CD19 antigen
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 GBL; G protein beta subunit-like
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K06071 PKN; protein kinase N [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; thioesterase superfamily member 4
K04382 PPP2C; protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; protein phosphatase 2 (formerly 2A), regulatory subunit A
K04354 PPP2R2; protein phosphatase 2 (formerly 2A), regulatory subunit B
K11583 PPP2R3; protein phosphatase 2 (formerly 2A), regulatory subunit B''
K11584 PPP2R5; protein phosphatase 2 (formerly 2A), regulatory subunit B'
K04079 htpG, HSP90A; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; cyclin D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; cyclin D2
K10152 CCND3; cyclin D3
K06626 CCNE; cyclin E
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; BCL2-antagonist of cell death
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator BCL-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 NR2B1, RXRA; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB; myb proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K04451 TP53, P53; tumor protein p53
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
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04150 mTOR signaling pathway [PATH:ko04150]
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K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 GBL; G protein beta subunit-like
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07204 RAPTOR; regulatory associated protein of mTOR
K08267 RICTOR; rapamycin-insensitive companion of mTOR
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K05448 VEGFA; vascular endothelial growth factor A
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K08269 ULK, ATG1; unc51-like kinase [EC:2.7.11.1]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04373 RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K03156 TNFA; tumor necrosis factor superfamily, member 2
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07298 STK11, LKB1; serine/threonine-protein kinase 11
K08271 LYK5, STRAD; protein kinase LYK5
K08272 CAB39, MO25; calcium binding protein 39
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
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04075 Plant hormone signal transduction [PATH:ko04075]
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Signaling molecules and interaction
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Cellular Processes
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Organismal Systems
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Immune system
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Endocrine system
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04911 Insulin secretion [PATH:ko04911]
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04910 Insulin signaling pathway [PATH:ko04910]
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K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2_3_4; insulin receptor substrate 2/3/4
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K06269 PPP1C; protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1, regulatory (inhibitor) subunit 3
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K02183 CALM; calmodulin
K00688 E2.4.1.1, glgP, PYG; starch phosphorylase [EC:2.4.1.1]
K13296 PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K07188 E3.1.1.79, LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
K06069 APKC; atypical protein kinase C [EC:2.7.11.13]
K07191 SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K07192 FLOT; flotillin
K07193 APS, SH2B2; SH2B adapter protein 2
K06086 SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
K04438 CRK, CRKII; proto-oncogene C-crk
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor (GEF) 1
K07194 RHOQ, TC10; Ras homolog gene family, member Q
K07195 EXOC7, EXO70; exocyst complex component 7
K07196 TRIP10, CIP4; thyroid hormone receptor interactor 10
K07197 SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
K11262 ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00844 HK; hexokinase [EC:2.7.1.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K07202 PGC1; peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03841 FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K01596 E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07204 RAPTOR; regulatory associated protein of mTOR
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K02158 BAD; BCL2-antagonist of cell death
K06279 SHC; src homology 2 domain-containing transforming protein C
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04375 ELK1; ETS domain-containing protein Elk-1
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K05696 PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K15909 SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
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04920 Adipocytokine signaling pathway [PATH:ko04920]
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03320 PPAR signaling pathway [PATH:ko03320]
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04912 GnRH signaling pathway [PATH:ko04912]
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04913 Ovarian Steroidogenesis [PATH:ko04913]
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04915 Estrogen signaling pathway [PATH:ko04915]
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04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
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04917 Prolactin signaling pathway [PATH:ko04917]
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04916 Melanogenesis [PATH:ko04916]
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04614 Renin-angiotensin system [PATH:ko04614]
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Circulatory system
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Digestive system
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Excretory system
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Nervous system
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Sensory system
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Development
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Environmental adaptation
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Human Diseases
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KEGG Orthology (KO)