KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
   Transcription
 
   Translation
     03010 Ribosome [PATH:ko03010]
     03011 Ribosome [BR:ko03011]
     03016 Transfer RNA biogenesis [BR:ko03016]
     00970 Aminoacyl-tRNA biosynthesis [PATH:ko00970]
     03013 RNA transport [PATH:ko03013]
       K01164  POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
       K14522  POP3; ribonuclease P/MRP protein subunit POP3 [EC:3.1.26.5]
       K14523  RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
       K03538  POP4, RPP29; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
       K03537  POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
       K14524  POP6; ribonuclease P/MRP protein subunit POP6 [EC:3.1.26.5]
       K14525  RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
       K14526  POP7, RPP2; ribonuclease P/MRP protein subunit POP7 [EC:3.1.26.5]
       K14527  RPP20, POP7; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
       K14528  POP8; ribonuclease P/MRP protein subunit POP8 [EC:3.1.26.5]
       K14529  RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
       K03539  RPP1, RPP30; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
       K03540  RPR2, RPP21; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
       K14530  RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
       K18213  PRORP; proteinaceous RNase P [EC:3.1.26.5]
       K14533  RPM2; ribonuclease P protein component, mitochondrial [EC:3.1.26.5]
       K00784  rnz; ribonuclease Z [EC:3.1.26.11]
       K00974  cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
       K07936  RAN; GTP-binding nuclear protein Ran
       K14288  XPOT; exportin-T
       K14289  XPO5; exportin-5
       K03231  EEF1A; elongation factor 1-alpha
       K14290  XPO1, CRM1; exportin-1
       K14291  PHAX; phosphorylated adapter RNA export protein
       K12882  NCBP1, CBP80; nuclear cap-binding protein subunit 1
       K12883  NCBP2, CBP20; nuclear cap-binding protein subunit 2
       K05019  CLNS1A; chloride channel, nucleotide-sensitive, 1A
       K02516  PRMT5, HSL7; protein arginine N-methyltransferase 5 [EC:2.1.1.125]
       K14292  TGS1; trimethylguanosine synthase [EC:2.1.1.-]
       K14293  KPNB1; importin subunit beta-1
       K13151  SNUPN, RNUT1; snurportin-1
       K07562  NMD3; nonsense-mediated mRNA decay protein 3
       K14294  WIBG, PYM; partner of Y14 and mago
       K09291  TPR; nucleoprotein TPR
       K14295  NUP50, NPAP60; nuclear pore complex protein Nup50
       K14296  NUP153; nuclear pore complex protein Nup153
       K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
       K14297  NUP98, ADAR2; nuclear pore complex protein Nup98-Nup96
       K14298  RAE1; mRNA export factor
       K14004  SEC13; protein transport protein SEC13
       K14299  SEH1; nucleoporin SEH1
       K14300  NUP133; nuclear pore complex protein Nup133
       K14301  NUP107; nuclear pore complex protein Nup107
       K14302  NUP37; nuclear pore complex protein Nup37
       K14303  NUP160; nuclear pore complex protein Nup160
       K14304  NUP85; nuclear pore complex protein Nup85
       K14305  NUP43; nuclear pore complex protein Nup43
       K14306  NUP62; nuclear pore complex protein Nup62
       K14307  NUPL1; nucleoporin p58/p45
       K14308  NUP54; nuclear pore complex protein Nup54
       K14309  NUP93; nuclear pore complex protein Nup93
       K14310  NUP205; nuclear pore complex protein Nup205
       K14311  NUP188; nuclear pore complex protein Nup188
       K14312  NUP155; nuclear pore complex protein Nup155
       K14313  NUP35, NUP53; nuclear pore complex protein Nup53
       K14314  NUP210, GP210; nuclear pore complex protein Nup210
       K14315  NDC1, TMEM48; nucleoporin NDC1
       K14316  POM121, NUP121; nuclear pore complex protein Nup121
       K14317  NUP214, CAN; nuclear pore complex protein Nup214
       K14318  NUP88; nuclear pore complex protein Nup88
       K12172  RANBP2, NUP358; E3 SUMO-protein ligase RanBP2
       K14319  RANGAP1; Ran GTPase-activating protein 1
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K12160  SUMO, SMT3; small ubiquitin-related modifier
       K14320  AAAS; aladin
       K14321  NUPL2, CG1; nucleoporin-like protein 2
       K13129  SMN; survival motor neuron protein
       K13130  SIP1, GEMIN2; survival of motor neuron protein-interacting protein 1
       K13131  DDX20, GEMIN3; ATP-dependent RNA helicase DDX20 [EC:3.6.4.13]
       K13132  GEMIN4; gem associated protein 4
       K13133  GEMIN5; gem associated protein 5
       K13134  GEMIN6, SIP2; gem associated protein 6
       K13135  GEMIN7, SIP3; gem associated protein 7
       K13136  GEMIN8; gem associated protein 8
       K13137  STRAP, UNRIP; serine-threonine kinase receptor-associated protein
       K03245  EIF3J; translation initiation factor 3 subunit J
       K03246  EIF3I; translation initiation factor 3 subunit I
       K03247  EIF3H; translation initiation factor 3 subunit H
       K03248  EIF3G; translation initiation factor 3 subunit G
       K03249  EIF3F; translation initiation factor 3 subunit F
       K03250  EIF3E, INT6; translation initiation factor 3 subunit E
       K03251  EIF3D; translation initiation factor 3 subunit D
       K03252  EIF3C; translation initiation factor 3 subunit C
       K03253  EIF3B; translation initiation factor 3 subunit B
       K03254  EIF3A; translation initiation factor 3 subunit A
       K03236  EIF1A; translation initiation factor 1A
       K03113  EIF1, SUI1; translation initiation factor 1
       K03262  EIF5; translation initiation factor 5
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K03238  EIF2S2; translation initiation factor 2 subunit 2
       K03242  EIF2S3; translation initiation factor 2 subunit 3
       K03239  EIF2B1; translation initiation factor eIF-2B subunit alpha
       K03754  EIF2B2; translation initiation factor eIF-2B subunit beta
       K03680  EIF2B4; translation initiation factor eIF-2B subunit delta
       K03241  EIF2B3; translation initiation factor eIF-2B subunit gamma
       K03240  EIF2B5; translation initiation factor eIF-2B subunit epsilon
       K03243  EIF5B; translation initiation factor 5B
       K03260  EIF4G; translation initiation factor 4G
       K03259  EIF4E; translation initiation factor 4E
       K03257  EIF4A; translation initiation factor 4A
       K03258  EIF4B; translation initiation factor 4B
       K13126  PABPC; polyadenylate-binding protein
       K14322  PAIP1; polyadenylate-binding protein-interacting protein 1
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K14283  TACC3, maskin; transforming acidic coiled-coil-containing protein 3
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K15516  FMR; fragile X mental retardation protein
       K12876  RBM8A, Y14; RNA-binding protein 8A
       K12877  MAGOH; protein mago nashi
       K14323  CASC3, MLN51; protein CASC3
       K13025  EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
       K14324  SAP18; histone deacetylase complex subunit SAP18
       K13114  PNN; pinin
       K12875  ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
       K14325  RNPS1; RNA-binding protein with serine-rich domain 1
       K12881  THOC4, ALY; THO complex subunit 4
       K12812  UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
       K12878  THOC1; THO complex subunit 1
       K12879  THOC2; THO complex subunit 2
       K13174  THOC5; THO complex subunit 5
       K13175  THOC6; THO complex subunit 6
       K13176  THOC7; THO complex subunit 7
       K12880  THOC3; THO complex subunit 3
       K13171  SRRM1, SRM160; serine/arginine repetitive matrix protein 1
       K14284  NXF1_2, TAP; nuclear RNA export factor 1/2
       K14285  NXT1_2, P15; NTF2-related export protein 1/2
       K14543  MTR2; mRNA transport regulator MTR2
       K14326  UPF1, RENT1; regulator of nonsense transcripts 1 [EC:3.6.4.-]
       K14327  UPF2, RENT2; regulator of nonsense transcripts 2
       K14328  UPF3, RENT3; regulator of nonsense transcripts 3
       K14276  U1snRNA; U1 spliceosomal RNA
       K14277  U2snRNA; U2 spliceosomal RNA
       K14278  U4snRNA; U4 spliceosomal RNA
       K14279  U5snRNA; U5 spliceosomal RNA
       K14280  U6snRNA; U6 spliceosomal RNA
       K14483  U3snoRNA, snR17; U3 small nucleolar RNA
     03015 mRNA surveillance pathway [PATH:ko03015]
     03008 Ribosome biogenesis in eukaryotes [PATH:ko03008]
     03009 Ribosome biogenesis [BR:ko03009]
     03029 Mitochondrial biogenesis [BR:ko03029]
     03012 Translation factors [BR:ko03012]
 
   Folding, sorting and degradation
 
   Replication and repair
 
   RNA family
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
       K05405  IL6; interleukin 6
       K05055  IL6R; interleukin 6 receptor
       K04692  STAT3; signal transducer and activator of transcription 3
       K10160  TLR4; toll-like receptor 4
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04526  INS; insulin
       K04357  EGF; epidermal growth factor
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03868  RBX1, ROC1; RING-box protein 1
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K08008  NOX, GP91; NADPH oxidase
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K16451  TIMP1; metallopeptidase inhibitor 1
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K05437  EPO; erythropoietin
       K14736  TF; transferrin
       K06503  TFRC, CD71; transferrin receptor
       K05448  VEGFA; vascular endothelial growth factor A
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K16366  EDN1; endothelin-1
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12334  NPPA; natriuretic peptide A
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K12077  PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
       K01689  ENO, eno; enolase [EC:4.2.1.11]
       K01103  PFKFB; 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
       K02161  BCL2; apoptosis regulator BCL-2
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K00161  PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
       K00162  PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2; toll-like receptor 2
       K10160  TLR4; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; CD19 antigen
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K04737  IL3RA; interleukin 3 receptor alpha
       K05055  IL6R; interleukin 6 receptor
       K05071  IL4R; interleukin 4 receptor
       K05072  IL7R; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K06626  CCNE; cyclin E
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; BCL2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB; myb proto-oncogene protein
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K16172  IRS1; insulin receptor substrate 1
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K08267  RICTOR; rapamycin-insensitive companion of mTOR
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K05448  VEGFA; vascular endothelial growth factor A
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K08269  ULK1_2_3, ATG1; serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K08272  CAB39, MO25; calcium binding protein 39
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K17453  PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
       K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
       K07190  PHKA_B; phosphorylase kinase alpha/beta subunit
       K02183  CALM; calmodulin
       K00688  E2.4.1.1, glgP, PYG; starch phosphorylase [EC:2.4.1.1]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07192  FLOT; flotillin
       K07193  APS, SH2B2; SH2B adapter protein 2
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K07194  RHOQ, TC10; Ras homolog gene family, member Q
       K07195  EXOC7, EXO70; exocyst complex component 7
       K07196  TRIP10, CIP4; thyroid hormone receptor interactor 10
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07201  FOXO1; forkhead box protein O1
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K02158  BAD; BCL2-antagonist of cell death
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases

[ BRITE | KEGG2 | KEGG ]
Last updated: July 21, 2014