KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
   Transcription
 
   Translation
 
   Folding, sorting and degradation
     03110 Chaperones and folding catalysts [BR:ko03110]
     03060 Protein export [PATH:ko03060]
     04141 Protein processing in endoplasmic reticulum [PATH:ko04141]
     04130 SNARE interactions in vesicular transport [PATH:ko04130]
     04131 SNAREs [BR:ko04131]
     04120 Ubiquitin mediated proteolysis [PATH:ko04120]
       K03178  UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.3.2.19]
       K10684  UBLE1A, SAE1; ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19]
       K10685  UBLE1B, SAE2, UBA2; ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]
       K10686  UBE1C, UBA3; ubiquitin-activating enzyme E1 C [EC:6.3.2.19]
       K10698  UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.3.2.19]
       K10699  UBE1L2, UBA6; ubiquitin-activating enzyme E1-like protein 2 [EC:6.3.2.19]
       K10573  UBE2A, UBC2, RAD6A; ubiquitin-conjugating enzyme E2 A [EC:6.3.2.19]
       K10574  UBE2B, RAD6B; ubiquitin-conjugating enzyme E2 B [EC:6.3.2.19]
       K06688  UBE2C, UBC11; ubiquitin-conjugating enzyme E2 C [EC:6.3.2.19]
       K06689  UBE2D_E, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19]
       K10687  UBE2F; ubiquitin-conjugating enzyme E2 F [EC:6.3.2.19]
       K10575  UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19]
       K04555  UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19]
       K10576  UBE2H, UBC8; ubiquitin-conjugating enzyme E2 H [EC:6.3.2.19]
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K10578  UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:6.3.2.19]
       K04554  UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19]
       K04552  UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19]
       K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6 [EC:6.3.2.19]
       K10579  UBE2M, UBC12; ubiquitin-conjugating enzyme E2 M [EC:6.3.2.19]
       K10580  UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:6.3.2.19]
       K10581  UBE2O; ubiquitin-conjugating enzyme E2 O [EC:6.3.2.19]
       K10582  UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19]
       K02207  UBE2R, UBC3, CDC34; ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19]
       K10583  UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S [EC:6.3.2.19]
       K10584  UBE2U; ubiquitin-conjugating enzyme E2 U [EC:6.3.2.19]
       K10688  UBE2W, UBC16; ubiquitin-conjugating enzyme E2 W [EC:6.3.2.19]
       K10585  UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:6.3.2.19]
       K04649  HIP2, UBC1; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19]
       K10586  BIRC6, BRUCE; baculoviral IAP repeat-containing protein 6 (apollon) [EC:6.3.2.19]
       K10587  UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:6.3.2.19]
       K10588  UBE3B; ubiquitin-protein ligase E3 B [EC:6.3.2.19]
       K10589  UBE3C; ubiquitin-protein ligase E3 C [EC:6.3.2.19]
       K04678  SMURF; E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19]
       K05632  AIP4, ITCH; atrophin-1 interacting protein 4 [EC:6.3.2.19]
       K05633  AIP5, WWP1; atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19]
       K05630  WWP2, AIP2; atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:6.3.2.19]
       K10590  TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19]
       K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
       K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:6.3.2.19]
       K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1 [EC:6.3.2.19]
       K10593  EDD1, UBR5; E3 ubiquitin-protein ligase EDD1 [EC:6.3.2.19]
       K10594  HERC1; E3 ubiquitin-protein ligase HERC1 [EC:6.3.2.19]
       K10595  HERC2; E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19]
       K10614  HERC3; E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19]
       K10615  HERC4; E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19]
       K10596  UBE4A; ubiquitin conjugation factor E4 A [EC:6.3.2.19]
       K10597  UBE4B, UFD2; ubiquitin conjugation factor E4 B [EC:6.3.2.19]
       K09561  STUB1, CHIP; STIP1 homology and U-box containing protein 1 [EC:6.3.2.19]
       K10598  PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
       K10599  PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:6.3.2.19]
       K10600  UBOX5, UIP5; U-box domain-containing protein 5
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K04556  PARK2; parkin [EC:6.3.2.19]
       K04506  SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19]
       K10054  PML, TRIM19; probable transcription factor PML
       K03175  TRAF6; TNF receptor-associated factor 6
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K10143  RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]
       K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:6.3.2.19]
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04706  PIAS1; E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-]
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K16064  PIAS3; E3 SUMO-protein ligase PIAS3 [EC:6.3.2.-]
       K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
       K10601  SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19]
       K10602  NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:6.3.2.19]
       K10603  AIRE; autoimmune regulator
       K10604  MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:6.3.2.19]
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K10606  FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19]
       K08285  TRIM18, MID1; midline 1 [EC:6.3.2.19]
       K10607  TRIM32, HT2A; tripartite motif-containing protein 32 [EC:6.3.2.19]
       K10608  TRIM37, MUL; tripartite motif-containing protein 37 [EC:6.3.2.19]
       K03868  RBX1, ROC1; RING-box protein 1
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K10260  FBXW7, SEL10; F-box and WD-40 domain protein 7
       K10099  FBXO2, NFB42; F-box protein 2
       K10291  FBXO4; F-box protein 4
       K03361  CDC4; F-box and WD-40 domain protein CDC4
       K10259  MET30; F-box and WD-40 domain protein MET30
       K03360  GRR1; F-box and leucine-rich repeat protein GRR1
       K03870  CUL2; cullin 2
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03869  CUL3; cullin 3
       K10456  KLHL19, KEAP1, INRF2; kelch-like protein 19
       K10447  KLHL9_13; kelch-like protein 9/13
       K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
       K03876  MEL26; BTB domain ubiquitin protein ligase cofactor
       K10609  CUL4; cullin 4
       K10610  DDB1; DNA damage-binding protein 1
       K10140  DDB2; DNA damage-binding protein 2
       K10570  ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
       K10571  DET1; de-etiolated-1
       K10611  RBX2, ROC2, RNF7; RING-box protein 2
       K10612  CUL5; cullin 5
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K10613  CUL7; cullin 7
       K10264  FBXW8; F-box and WD-40 domain protein 8
       K03358  APC11; anaphase-promoting complex subunit 11
       K03349  APC2; anaphase-promoting complex subunit 2
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
     04121 Ubiquitin system [BR:ko04121]
     04122 Sulfur relay system [PATH:ko04122]
     03050 Proteasome [PATH:ko03050]
     03051 Proteasome [BR:ko03051]
     03018 RNA degradation [PATH:ko03018]
 
   Replication and repair
 
   RNA family
 
 Environmental Information Processing
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K04681  RBL1; retinoblastoma-like protein 1
       K16332  RBL2; retinoblastoma-like protein 2
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04682  E2F4_5; transcription factor E2F4/5
       K04683  TFDP1; transcription factor Dp-1
       K09392  TFDP2; transcription factor Dp-2
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04377  MYC; Myc proto-oncogene protein
       K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K06623  CDKN2D, P19, INK4D; cyclin-dependent kinase inhibitor 2D
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K09993  CDKN1C, P57, KIP2; cyclin-dependent kinase inhibitor 1C
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03347  CUL1, CDC53; cullin 1
       K03868  RBX1, ROC1; RING-box protein 1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K06627  CCNA; cyclin A
       K02213  CDC6; cell division control protein 6
       K06628  CDC45; cell division control protein 45
       K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
       K06629  ASK, DBF4; activator of S phase kinase
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K05868  CCNB; cyclin B
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K06632  WEE1; wee1-like protein kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K06634  CCNH; cyclin H
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K06671  STAG1_2, SCC3, IRR1; cohesin complex subunit SA-1/2
       K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
       K08866  TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04802  PCNA; proliferating cell nuclear antigen
       K06644  SFN; stratifin
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K02603  ORC1; origin recognition complex subunit 1
       K02604  ORC2; origin recognition complex subunit 2
       K02605  ORC3; origin recognition complex subunit 3
       K02606  ORC4; origin recognition complex subunit 4
       K02607  ORC5; origin recognition complex subunit 5
       K02608  ORC6; origin recognition complex subunit 6
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast [PATH:ko04111]
       K06646  CLN3; G1/S-specific cyclin CLN3
       K04563  CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
       K06649  SWI4; regulatory protein SWI4
       K06648  SWI6; regulatory protein SWI6
       K12760  CLN1; G1/S-specific cyclin CLN1
       K06650  CLN2; G1/S-specific cyclin CLN2
       K03085  SIC1; substrate and inhibitor of the cyclin-dependent protein kinase CDC28
       K06647  MBP1; transcription factor MBP1
       K06651  CLB5_6; S-phase entry cyclin 5/6
       K02213  CDC6; cell division control protein 6
       K02603  ORC1; origin recognition complex subunit 1
       K02604  ORC2; origin recognition complex subunit 2
       K02605  ORC3; origin recognition complex subunit 3
       K02606  ORC4; origin recognition complex subunit 4
       K02607  ORC5; origin recognition complex subunit 5
       K02608  ORC6; origin recognition complex subunit 6
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
       K12414  TAH11; DNA replication licensing factor, required for pre-replication complex assembly
       K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
       K02309  DBF4; regulatory subunit for Cdc7p protein kinase
       K06628  CDC45; cell division control protein 45
       K12412  MCM1; pheromone receptor transcription factor
       K12413  WHI5; G1-specific transcriptional repressor WHI5
       K06652  FAR1; cyclin-dependent kinase inhibitor FAR1
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03347  CUL1, CDC53; cullin 1
       K03868  RBX1, ROC1; RING-box protein 1
       K03360  GRR1; F-box and leucine-rich repeat protein GRR1
       K03361  CDC4; F-box and WD-40 domain protein CDC4
       K06656  PCL1; G1/S-specific cyclin PLC1
       K06657  PCL2; G1/S-specific cyclin PLC2
       K06655  PHO85; negative regulator of the PHO system [EC:2.7.11.22]
       K06653  PHO81; CDK inhibitor PHO81
       K06654  PHO80; phosphate system cyclin PHO80
       K06658  PHO4; phosphate system positive regulatory protein PHO4
       K02646  PHO2; regulatory protein PHO2
       K06659  CLB3_4; G2/mitotic-specific cyclin 3/4
       K08866  TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06680  MAD3; spindle assembly checkpoint component MAD3
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K02307  DAM1; DASH complex subunit DAM1
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K02627  PDS1; cell cycle regulator
       K02365  ESP1; separase [EC:3.4.22.49]
       K12575  SLK19; kinetochore protein SLK19
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K12576  SPO12; sporulation-specific protein 12
       K12577  FOB1; DNA replication fork-blocking protein FOB1
       K06687  NET1, ESC5; nucleolar protein involved in exit from mitosis
       K06660  CDC5; cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]
       K02181  BFA1; cell cycle arrest protein BFA1
       K02179  BUB2; cell cycle arrest protein BUB2
       K06681  LTE1; Gdp/GTP exchange factor required for growth at low temperatures
       K06682  TEM1; Gtp-binding protein of the ras superfamily involved in termination of M-phase
       K06683  CDC15; cell division control protein CDC15 [EC:2.7.11.1]
       K06684  DBF2; cell cycle protein kinase DBF2 [EC:2.7.11.-]
       K06686  DBF20; cell cycle protein kinase DBF20 [EC:2.7.11.-]
       K06685  MOB1, Mats; MOB kinase activator 1
       K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
       K09202  SWI5; regulatory protein SWI5
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K02220  CLB1_2; G2/mitotic-specific cyclin 1/2
       K02555  MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
       K06667  CAK1; serine/threonine-protein kinase CAK1 [EC:2.7.11.22]
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
       K10259  MET30; F-box and WD-40 domain protein MET30
       K02515  HSL1; serine/threonine-protein kinase HSL1,negative regulator of Swe1 kinase [EC:2.7.11.-]
       K02516  PRMT5, HSL7; protein arginine N-methyltransferase 5 [EC:2.1.1.125]
       K06668  GIN4; serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
       K02544  MEC3; G2-specific checkpoint protein
       K06663  DDC1; DNA damage checkpoint protein
       K02830  HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
       K06662  HRAD17, RAD24; cell cycle checkpoint protein
       K02543  MEC1; cell cycle checkpoint protein MEC1
       K12578  LCD1, ddc2; DNA damage checkpoint protein LCD1
       K06661  RAD9; DNA repair protein RAD9
       K11272  MRC1; mediator of replication checkpoint protein 1
       K02831  RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K09175  RFXX; regulatory factor X, other
       K06665  SSN6; glucose repression mediator protein
       K06666  TUP1; glucose repression regulatory protein TUP1
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
       K06671  STAG1_2, SCC3, IRR1; cohesin complex subunit SA-1/2
       K06672  SCC2, NIPBL; cohesin loading factor subunit SCC2
       K06673  SCC4; cohesin loading factor subunit SCC4
       K06674  SMC2; structural maintenance of chromosome 2
       K06675  SMC4; structural maintenance of chromosome 4
       K06676  BRRN1, BRN1, CAPH; condensin complex subunit 2
       K06677  YCS4, CNAP1, CAPD2; condensin complex subunit 1
       K06678  YCG1, CAPG; condensin complex subunit 3
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
       K06646  CLN3; G1/S-specific cyclin CLN3
       K04563  CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
       K06649  SWI4; regulatory protein SWI4
       K06648  SWI6; regulatory protein SWI6
       K06650  CLN2; G1/S-specific cyclin CLN2
       K09358  MATA1; mating-type protein A1
       K09359  MATA2; mating-type protein A2
       K09235  RME1; zinc finger protein RME1
       K08139  HXT; MFS transporter, SP family, sugar:H+ symporter
       K12761  SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
       K12762  K12762, GPR1; G protein-coupled receptor GPR1
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K12763  SOK2; protein SOK2
       K12764  IME1; meiosis-inducing protein 1
       K12765  IME2; meiosis induction protein kinase IME2/SME1 [EC:2.7.11.1]
       K03085  SIC1; substrate and inhibitor of the cyclin-dependent protein kinase CDC28
       K06651  CLB5_6; S-phase entry cyclin 5/6
       K02213  CDC6; cell division control protein 6
       K12414  TAH11; DNA replication licensing factor, required for pre-replication complex assembly
       K02603  ORC1; origin recognition complex subunit 1
       K02604  ORC2; origin recognition complex subunit 2
       K02605  ORC3; origin recognition complex subunit 3
       K02606  ORC4; origin recognition complex subunit 4
       K02607  ORC5; origin recognition complex subunit 5
       K02608  ORC6; origin recognition complex subunit 6
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
       K06628  CDC45; cell division control protein 45
       K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
       K02309  DBF4; regulatory subunit for Cdc7p protein kinase
       K12766  MDS1, RIM11; serine/threonine-protein kinase MDS1/RIM11 [EC:2.7.11.1]
       K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
       K09243  UME6; transcriptional regulatory protein UME6
       K10878  SPO11; meiotic recombination protein SPO11
       K10872  DMC1; meiotic recombination protein DMC1
       K12768  ZIP1; synaptonemal complex protein ZIP1
       K12769  NDT80; meiosis-specific transcription factor NDT80
       K12770  GIP1; GLC7-interacting protein 1
       K12771  SPS1; sporulation-specific protein 1 [EC:2.7.11.1]
       K12772  SPS4; sporulation-specific protein 4
       K12773  SPR3; sporulation-regulated protein 3
       K06659  CLB3_4; G2/mitotic-specific cyclin 3/4
       K06660  CDC5; cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]
       K12576  SPO12; sporulation-specific protein 12
       K12575  SLK19; kinetochore protein SLK19
       K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
       K12774  MAM1; monopolin complex subunit MAM1
       K12775  LRS4; monopolin complex subunit LRS4
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K12776  MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1]
       K12777  RED1; protein RED1
       K12778  HOP1; meiosis-specific protein HOP1
       K12779  SUM1; suppressor of MAR1-1 protein
       K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
       K02544  MEC3; G2-specific checkpoint protein
       K06663  DDC1; DNA damage checkpoint protein
       K02830  HRAD1, RAD17; cell cycle checkpoint protein [EC:3.1.11.2]
       K06662  HRAD17, RAD24; cell cycle checkpoint protein
       K02543  MEC1; cell cycle checkpoint protein MEC1
       K06661  RAD9; DNA repair protein RAD9
       K02831  RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K02627  PDS1; cell cycle regulator
       K02365  ESP1; separase [EC:3.4.22.49]
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K12780  REC8; meiotic recombination protein REC8, fungi type
       K06671  STAG1_2, SCC3, IRR1; cohesin complex subunit SA-1/2
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K11582  SGO1; shugoshin
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K12781  MND2; anaphase-promoting complex subunit MND2
       K12782  AMA1; meiosis-specific APC/C activator protein AMA1
       K12783  SSP1; sporulation-specific protein 1
       K06683  CDC15; cell division control protein CDC15 [EC:2.7.11.1]
     04114 Oocyte meiosis [PATH:ko04114]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K08556  NR3C3, PGR; progesterone receptor
       K08557  NR3C4, AR; androgen receptor
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K11481  AURKA; aurora kinase A [EC:2.7.11.1]
       K02602  ORB; oo18 RNA-binding protein
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K08694  SPDY, RINGO; speedy
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K08836  SLK; STE20-like kinase [EC:2.7.11.1]
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K13056  C3H-4; CCCH zinc finger protein C3H-4
       K03868  RBX1, ROC1; RING-box protein 1
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K10292  FBXO5, EMI1; F-box protein 5
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K10318  FBXO43, EMI2; F-box protein 43
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K13054  REC8L; meiotic recombination protein REC8, animal type
       K13055  STAG3; cohesin complex subunit SA-3
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K06626  CCNE; cyclin E
       K11580  SGOL1; shugoshin-like 1
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
     04210 Apoptosis [PATH:ko04210]
     04115 p53 signaling pathway [PATH:ko04115]
 
   Cellular commiunity
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
       K08556  NR3C3, PGR; progesterone receptor
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02602  ORB; oo18 RNA-binding protein
       K08694  SPDY, RINGO; speedy
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K06627  CCNA; cyclin A
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K05868  CCNB; cyclin B
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K07827  KRAS, KRAS2; GTPase KRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06724  NRP1; neuropilin 1
       K06527  VCAM1; vascular cell adhesion molecule 1
       K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
       K06451  CD3E; T-cell surface glycoprotein CD3 epsilon chain
       K06452  CD3G; T-cell surface glycoprotein CD3 gamma chain
       K06490  ICAM1; intercellular adhesion molecule 1
       K05718  ITGAL; integrin alpha L
       K06464  ITGB2; integrin beta 2
       K06271  TLN; talin
       K04377  MYC; Myc proto-oncogene protein
       K08874  TRRAP; transformation/transcription domain-associated protein
       K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
       K10151  CCND2; cyclin D2
       K15304  RANBP3; Ran-binding protein 3
       K07936  RAN; GTP-binding nuclear protein Ran
       K14290  XPO1, CRM1; exportin-1
       K06751  MHC1; major histocompatibility complex, class I
       K08057  CALR; calreticulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K08054  CANX; calnexin
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05770  BZRP; benzodiazapine receptor
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
       K06635  PTTG; securin
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04802  PCNA; proliferating cell nuclear antigen
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04503  CCND1; cyclin D1
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K04690  FZDN, fz3; frizzled
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02085  APC; adenomatosis polyposis coli protein
       K12076  DLG1; disks large protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04448  JUN; transcription factor AP-1
       K15307  GPS2; G protein pathway suppressor 2
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K05429  IL2; interleukin 2
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05433  IL15; interleukin 15
       K05074  IL15RA; interleukin 15 receptor alpha
       K05405  IL6; interleukin 6
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K15308  TTP; tristetraprolin
       K08065  NFYB; nuclear transcription Y subunit beta
       K06752  MHC2; major histocompatibility complex, class II
       K04378  SRF; serum response factor
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09438  SPI1; transcription factor PU.1
       K02678  ETS, pnt; c-ets proto-oncogene protein
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04379  FOS; proto-oncogene protein c-fos
       K09203  EGR1; early growth response protein 1
       K12496  EGR2; early growth response protein 2
       K04502  FOSL1; fos-like antigen 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09052  CREM; cAMP response element modulator
       K09053  ATF1; activating transcription factor 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K09032  ATF3, LRF1; activating transcription factor 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09027  XBP1; X box-binding protein 1
       K15309  CRTC1, TORC1; CREB-regulated transcription coactivator 1
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16334  CRTC3, TORC3; CREB-regulated transcription coactivator 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09063  TCF3, E2A; transcription factor E2-alpha
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K09420  MYB; myb proto-oncogene protein
       K09421  MYBL; myb-related protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K15310  TP53INP1; tumor protein p53-inducible nuclear protein 1
       K09341  MSX; homeobox protein MSX
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05168 Herpes simplex infection [PATH:ko05168]
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: September 21, 2014