KEGG Orthology (KO)

[ Brite menu | Organism menu | Download htext ]
    

1st Level  2nd Level  3rd Level  4th Level 

 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
     00230 Purine metabolism [PATH:ko00230]
       K13988  NUDT9; ADP-ribose pyrophosphatase [EC:3.6.1.13]
       K01515  nudF; ADP-ribose pyrophosphatase [EC:3.6.1.13]
       K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
       K13987  NUDT5; ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase [EC:3.6.1.13 3.6.1.58 3.6.1.-]
       K18453  NUDT23; ADP-ribose/FAD diphosphatase [EC:3.6.1.13 3.6.1.18]
       K08312  nudE; ADP-ribose diphosphatase [EC:3.6.1.-]
       K18447  NUDX14; ADP-sugar diphosphatase [EC:3.6.1.21]
       K01839  deoB; phosphopentomutase [EC:5.4.2.7]
       K01835  pgm; phosphoglucomutase [EC:5.4.2.2]
       K15778  pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
       K15779  PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
       K00948  PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
       K00764  purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
       K11787  GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
       K11788  ADE5; phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
       K01945  purD; phosphoribosylamine--glycine ligase [EC:6.3.4.13]
       K13713  purCD; fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
       K00601  E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
       K11175  purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
       K08289  purT; phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2]
       K01952  purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
       K01933  purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
       K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
       K11808  ADE2; phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21]
       K01589  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
       K01588  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
       K01923  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
       K01756  purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]
       K00602  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
       K01492  E2.1.2.3; phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.3]
       K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
       K11176  purO; IMP cyclohydrolase [EC:3.5.4.10]
       K00759  APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]
       K01081  E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
       K11751  ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
       K03787  surE; 5'-nucleotidase [EC:3.1.3.5]
       K08723  yjjG; 5'-nucleotidase [EC:3.1.3.5]
       K00892  gsk; inosine kinase [EC:2.7.1.73]
       K03783  punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K03784  deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K03815  xapA; xanthosine phosphorylase [EC:2.4.2.-]
       K01239  iunH; purine nucleosidase [EC:3.2.2.1]
       K10213  rihB; ribosylpyrimidine nucleosidase [EC:3.2.2.8]
       K00760  hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
       K15780  tilS-hprT; bifunctional protein TilS/HprT [EC:6.3.4.19 2.4.2.8]
       K00088  guaB; IMP dehydrogenase [EC:1.1.1.205]
       K00940  ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]
       K18533  AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
       K01510  ENTPD1_3_8; apyrase [EC:3.6.1.5]
       K14641  APY1_2; apyrase [EC:3.6.1.5]
       K14642  YND1; golgi apyrase [EC:3.6.1.5]
       K12304  CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
       K12305  ENTPD4, LALP70; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
       K01511  ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
       K16855  NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
       K01519  ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.19]
       K02428  rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
       K04765  mazG; ATP diphosphatase [EC:3.6.1.8]
       K00769  gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
       K03816  xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
       K00106  XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
       K00087  ygeS, xdhA; xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4]
       K13479  ygeT, xdhB; xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4]
       K13480  ygeU, xdhC; xanthine dehydrogenase iron-sulfur-binding subunit
       K13481  xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]
       K13482  xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]
       K11177  yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
       K11178  yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
       K13483  yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
       K01518  NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
       K18445  ndx1; diadenosine hexaphosphate hydrolase (ATP-forming) [EC:3.6.1.61]
       K01951  guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
       K00364  E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]
       K01487  E3.5.4.3, guaD; guanine deaminase [EC:3.5.4.3]
       K00942  E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00524  nrdJ; ribonucleotide reductase, class II [EC:1.17.4.1]
       K00525  E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
       K00526  E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
       K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
       K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
       K00527  nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2]
       K00904  DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
       K15518  dgk; deoxyguanosine kinase [EC:2.7.1.113]
       K01129  dgt; dGTPase [EC:3.1.5.1]
       K03040  rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
       K03043  rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
       K03046  rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
       K13797  rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
       K03048  rpoE; DNA-directed RNA polymerase subunit delta
       K03060  rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
       K03042  rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
       K03041  rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
       K03044  rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
       K03045  rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
       K13798  K13798, rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
       K03053  rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
       K03055  rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
       K03058  rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
       K03047  rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
       K03049  rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
       K03050  rpoE2; DNA-directed RNA polymerase subunit E" [EC:2.7.7.6]
       K03056  rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
       K03059  rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
       K03051  rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
       K03052  rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
       K03054  rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
       K02999  RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
       K03002  RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
       K03000  RPA12, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
       K03001  RPA14; DNA-directed RNA polymerase I subunit RPA14
       K03003  RPA34; DNA-directed RNA polymerase I subunit RPA34
       K03004  RPA43; DNA-directed RNA polymerase I subunit RPA43
       K03005  RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
       K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
       K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
       K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
       K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
       K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
       K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
       K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
       K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
       K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
       K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K02319  DPA, polB1; DNA polymerase I [EC:2.7.7.7]
       K02322  DPB1; DNA polymerase II large subunit [EC:2.7.7.7]
       K02323  DPB2; DNA polymerase II small subunit [EC:2.7.7.7]
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.-]
       K02685  PRI2; DNA primase large subunit [EC:2.7.7.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K01139  spoT, HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
       K01514  PRUNE, PPX1; exopolyphosphatase [EC:3.6.1.11]
       K01524  ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
       K00951  relA; GTP pyrophosphokinase [EC:2.7.6.5]
       K07816  E2.7.6.5X; putative GTP pyrophosphokinase [EC:2.7.6.5]
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K05851  E4.6.1.1A, cyaA; adenylate cyclase, class 1 [EC:4.6.1.1]
       K05873  E4.6.1.1B, cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K11265  ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
       K11029  cyaA; anthrax edema toxin adenylate cyclase [EC:4.6.1.1]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12320  GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
       K12321  GUCY2D_E_F; guanylate cyclase 2D/E/F [EC:4.6.1.2]
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K01769  E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
       K01120  cpdP; 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17]
       K13755  PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13762  PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
       K08718  PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
       K13756  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
       K13757  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
       K13758  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
       K13759  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
       K13760  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
       K13763  PDE6N; cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35]
       K13761  PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
       K18438  PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
       K13298  PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
       K01939  purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]
       K01490  AMPD; AMP deaminase [EC:3.5.4.6]
       K00856  E2.7.1.20, ADK; adenosine kinase [EC:2.7.1.20]
       K00893  DCK; deoxycitidine kinase [EC:2.7.1.74]
       K15519  dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]
       K01488  add, ADA; adenosine deaminase [EC:3.5.4.4]
       K01241  amn; AMP nucleosidase [EC:3.2.2.4]
       K01486  ade; adenine deaminase [EC:3.5.4.2]
       K01119  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6]
       K08693  yfkN; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5]
       K00939  adk, AK; adenylate kinase [EC:2.7.4.3]
       K18532  AK6, FAP7; adenylate kinase [EC:2.7.4.3]
       K00944  AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
       K01509  ENTPD2; adenosinetriphosphatase [EC:3.6.1.3]
       K06928  NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
       K10353  E2.7.1.76, dak; deoxyadenosine kinase [EC:2.7.1.76]
       K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
       K13293  PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
       K18436  PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
       K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
       K13294  PDEB2, PDE2B; cAMP-specific phosphodiesterase [EC:3.1.4.53]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K18424  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
       K00988  APA1_2; ATP adenylyltransferase [EC:2.7.7.53]
       K01525  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]
       K13811  PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
       K00955  cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
       K00860  cysC; adenylylsulfate kinase [EC:2.7.1.25]
       K01513  ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
       K00956  cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
       K00957  cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
       K00958  sat, met3; sulfate adenylyltransferase [EC:2.7.7.4]
       K00365  uaZ; urate oxidase [EC:1.7.3.3]
       K16838  pucL; urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:1.7.3.3 4.1.1.97]
       K16839  hpxO; FAD-dependent urate hydroxylase [EC:1.14.13.113]
       K07127  uraH, pucM, hiuH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]
       K13484  TTHL; 5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.97]
       K13485  PRHOXNB, URAD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
       K16840  hpxQ; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
       K16841  hpxA; allantoin racemase [EC:5.1.99.3]
       K01466  allB; allantoinase [EC:3.5.2.5]
       K16842  hpxB; allantoinase [EC:3.5.2.5]
       K01477  alc, ALLC; allantoicase [EC:3.5.3.4]
       K02083  allC; allantoate deiminase [EC:3.5.3.9]
       K14977  ylbA, UGHY; (S)-ureidoglycine aminohydrolase [EC:3.5.3.26]
       K18151  UAH; ureidoglycolate amidohydrolase [EC:3.5.1.116]
       K01483  allA; ureidoglycolate lyase [EC:4.3.2.3]
       K16856  ugl; ureidoglycolate lyase [EC:4.3.2.3]
       K01427  URE; urease [EC:3.5.1.5]
       K01428  ureC; urease subunit alpha [EC:3.5.1.5]
       K01429  ureB; urease subunit beta [EC:3.5.1.5]
       K01430  ureA; urease subunit gamma [EC:3.5.1.5]
       K14048  ureAB; urease subunit gamma/beta [EC:3.5.1.5]
       K00073  allD; ureidoglycolate dehydrogenase (NAD+) [EC:1.1.1.350]
       K00926  arcC; carbamate kinase [EC:2.7.2.2]
     00240 Pyrimidine metabolism [PATH:ko00240]
       K11540  CAD; carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
       K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
       K01954  K01954; carbamoyl-phosphate synthase [EC:6.3.5.5]
       K01955  carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
       K01956  carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
       K00609  pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
       K00610  pyrI; aspartate carbamoyltransferase regulatory subunit
       K00608  pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2]
       K01465  URA4, pyrC; dihydroorotase [EC:3.5.2.3]
       K17828  pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
       K02823  pyrDII; dihydroorotate dehydrogenase electron transfer subunit
       K00226  pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
       K00254  DHODH, pyrD; dihydroorotate dehydrogenase [EC:1.3.5.2]
       K13421  UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
       K00762  pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
       K01591  pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
       K00945  cmk; cytidylate kinase [EC:2.7.4.14]
       K13799  panC-cmk; pantoate ligase / cytidylate kinase [EC:6.3.2.1 2.7.4.14]
       K13800  CMPK1, UMPK; UMP-CMP kinase [EC:2.7.4.- 2.7.4.14]
       K13809  CMPK2; UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14]
       K09903  pyrH; uridylate kinase [EC:2.7.4.22]
       K00940  ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]
       K18533  AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
       K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
       K01510  ENTPD1_3_8; apyrase [EC:3.6.1.5]
       K14641  APY1_2; apyrase [EC:3.6.1.5]
       K14642  YND1; golgi apyrase [EC:3.6.1.5]
       K12304  CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
       K12305  ENTPD4, LALP70; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
       K01511  ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
       K01519  ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.19]
       K01937  pyrG, CTPS; CTP synthase [EC:6.3.4.2]
       K03040  rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
       K03043  rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
       K03046  rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
       K13797  rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
       K03048  rpoE; DNA-directed RNA polymerase subunit delta
       K03060  rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
       K03042  rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
       K03041  rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
       K03044  rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
       K03045  rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
       K13798  K13798, rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
       K03053  rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
       K03055  rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
       K03058  rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
       K03047  rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
       K03049  rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
       K03050  rpoE2; DNA-directed RNA polymerase subunit E" [EC:2.7.7.6]
       K03056  rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
       K03059  rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
       K03051  rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
       K03052  rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
       K03054  rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
       K02999  RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
       K03002  RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
       K03000  RPA12, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
       K03001  RPA14; DNA-directed RNA polymerase I subunit RPA14
       K03003  RPA34; DNA-directed RNA polymerase I subunit RPA34
       K03004  RPA43; DNA-directed RNA polymerase I subunit RPA43
       K03005  RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
       K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
       K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
       K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
       K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
       K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
       K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
       K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
       K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
       K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
       K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02319  DPA, polB1; DNA polymerase I [EC:2.7.7.7]
       K02322  DPB1; DNA polymerase II large subunit [EC:2.7.7.7]
       K02323  DPB2; DNA polymerase II small subunit [EC:2.7.7.7]
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.-]
       K02685  PRI2; DNA primase large subunit [EC:2.7.7.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K01494  dcd; dCTP deaminase [EC:3.5.4.13]
       K00876  udk, UCK; uridine kinase [EC:2.7.1.48]
       K01081  E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
       K11751  ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
       K03787  surE; 5'-nucleotidase [EC:3.1.3.5]
       K08723  yjjG; 5'-nucleotidase [EC:3.1.3.5]
       K00757  udp, UPP; uridine phosphorylase [EC:2.4.2.3]
       K01240  URH1; uridine nucleosidase [EC:3.2.2.3]
       K00761  upp, UPRT; uracil phosphoribosyltransferase [EC:2.4.2.9]
       K02825  pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
       K00207  DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
       K17722  preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1]
       K17723  preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1]
       K01464  DPYS, dht, hydA; dihydropyrimidinase [EC:3.5.2.2]
       K01431  UPB1; beta-ureidopropionase [EC:3.5.1.6]
       K09018  rutA; pyrimidine oxygenase [EC:1.14.99.46]
       K09024  rutF; flavin reductase [EC:1.5.1.-]
       K09020  rutB; ureidoacrylate peracid hydrolase [EC:3.5.1.110]
       K09021  rutC; aminoacrylate peracid reductase
       K09023  rutD; aminoacrylate hydrolase [EC:3.5.1.-]
       K16066  ydfG; malonic semialdehyde reductase [EC:1.1.1.-]
       K09019  rutE; 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-]
       K00756  E2.4.2.2, pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]
       K10213  rihB; ribosylpyrimidine nucleosidase [EC:3.2.2.8]
       K01485  codA; cytosine deaminase [EC:3.5.4.1]
       K04765  mazG; ATP diphosphatase [EC:3.6.1.8]
       K00384  trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
       K00527  nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2]
       K00524  nrdJ; ribonucleotide reductase, class II [EC:1.17.4.1]
       K00525  E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
       K00526  E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
       K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
       K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
       K16904  DCTPP1; dCTP diphosphatase [EC:3.6.1.12]
       K09887  E3.5.4.30; dCTP deaminase (dUMP-forming) [EC:3.5.4.30]
       K01520  dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]
       K00560  thyA, TYMS; thymidylate synthase [EC:2.1.1.45]
       K13998  DHFR-TS; dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
       K03465  E2.1.1.148, thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148]
       K01489  cdd, CDA; cytidine deaminase [EC:3.5.4.5]
       K00758  deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4]
       K03783  punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K03784  deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K00893  DCK; deoxycitidine kinase [EC:2.7.1.74]
       K15519  dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]
       K01493  comEB; dCMP deaminase [EC:3.5.4.12]
       K08728  E2.4.2.6; nucleoside deoxyribosyltransferase [EC:2.4.2.6]
       K00857  tdk, TK; thymidine kinase [EC:2.7.1.21]
       K00943  tmk, DTYMK; dTMP kinase [EC:2.7.4.9]
       K01119  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6]
       K08693  yfkN; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5]
       K01518  NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
       K16328  psuK; pseudouridine kinase [EC:2.7.1.83]
       K16329  psuG; pseudouridine-5'-phosphate glycosidase [EC:3.2.-.-]
       K16330  K16330; pseudouridine-5'-phosphate glycosidase / pseudouridine kinase [EC:3.2.-.- 2.7.1.83]
       K01718  E4.2.1.70; pseudouridylate synthase [EC:4.2.1.70]
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
   Transcription
 
   Translation
 
   Folding, sorting and degradation
 
   Replication and repair
     03030 DNA replication [PATH:ko03030]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02314  dnaB; replicative DNA helicase [EC:3.6.4.12]
       K02316  dnaG; DNA primase [EC:2.7.7.-]
       K03111  ssb; single-strand DNA-binding protein
       K03469  E3.1.26.4A, RNASEH1, rnhA; ribonuclease HI [EC:3.1.26.4]
       K03470  rnhB; ribonuclease HII [EC:3.1.26.4]
       K03471  rnhC; ribonuclease HIII [EC:3.1.26.4]
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.-]
       K02685  PRI2; DNA primase large subunit [EC:2.7.7.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10741  RPA4; replication factor A4
       K10740  RPA3; replication factor A3
       K04802  PCNA; proliferating cell nuclear antigen
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K10742  DNA2; DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12]
       K10743  RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
       K10744  RNASEH2B; ribonuclease H2 subunit B
       K10745  RNASEH2C; ribonuclease H2 subunit C
       K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.-.-.-]
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
     03032 DNA replication proteins [BR:ko03032]
     03036 Chromosome and associated proteins [BR:ko03036]
     03410 Base excision repair [PATH:ko03410]
       K10563  mutM, fpg; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
       K05522  nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
       K03660  OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
       K10773  NTH; endonuclease III [EC:4.2.99.18]
       K10567  NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
       K10568  NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
       K10569  NEIL3; endonuclease VIII-like 3
       K01247  alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
       K13529  ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
       K01246  tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
       K03648  UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]
       K03649  MUG, TDG; TDG/mug DNA glycosylase family protein [EC:3.2.2.-]
       K10800  SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
       K03575  mutY; A/G-specific adenine glycosylase [EC:3.2.2.-]
       K03652  MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
       K10801  MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
       K01142  E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]
       K01151  nfo; deoxyribonuclease IV [EC:3.1.21.2]
       K10771  APEX1; AP endonuclease 1 [EC:4.2.99.18]
       K10772  APEX2; AP endonuclease 2 [EC:4.2.99.18]
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K03512  POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
       K10802  HMGB1; high mobility group protein B1
       K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K10803  XRCC1; DNA-repair protein XRCC1
       K10776  LIG3; DNA ligase 3 [EC:6.5.1.1]
       K10798  PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
       K04802  PCNA; proliferating cell nuclear antigen
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.-.-.-]
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
     03420 Nucleotide excision repair [PATH:ko03420]
       K03723  mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]
       K03701  uvrA; excinuclease ABC subunit A
       K03702  uvrB; excinuclease ABC subunit B
       K03703  uvrC; excinuclease ABC subunit C
       K03657  uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K03868  RBX1, ROC1; RING-box protein 1
       K10609  CUL4; cullin 4
       K10610  DDB1; DNA damage-binding protein 1
       K10140  DDB2; DNA damage-binding protein 2
       K10838  XPC; xeroderma pigmentosum group C-complementing protein
       K10839  RAD23, HR23; UV excision repair protein RAD23
       K10840  CETN2; centrin-2
       K10570  ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
       K10841  ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K10842  MNAT1; CDK-activating kinase assembly factor MAT1
       K06634  CCNH; cyclin H
       K10843  ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
       K10844  ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
       K10845  TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K10846  ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
       K10847  XPA; DNA-repair protein complementing XP-A cells
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
       K10849  ERCC1; DNA excision repair protein ERCC-1
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04802  PCNA; proliferating cell nuclear antigen
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
     03430 Mismatch repair [PATH:ko03430]
       K03555  mutS; DNA mismatch repair protein MutS
       K07456  mutS2; DNA mismatch repair protein MutS2
       K03572  mutL; DNA mismatch repair protein MutL
       K03573  mutH; DNA mismatch repair protein MutH
       K03657  uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
       K01141  E3.1.11.1, sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
       K03601  xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
       K03602  xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
       K10857  exoX; exodeoxyribonuclease X [EC:3.1.11.-]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K03111  ssb; single-strand DNA-binding protein
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K06223  dam; DNA adenine methylase [EC:2.1.1.72]
       K10858  PMS2; DNA mismatch repair protein PMS2
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08737  MSH6; DNA mismatch repair protein MSH6
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08739  MLH3; DNA mismatch repair protein MLH3
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K04802  PCNA; proliferating cell nuclear antigen
       K10746  EXO1; exonuclease 1 [EC:3.1.-.-]
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
     03440 Homologous recombination [PATH:ko03440]
       K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
       K03111  ssb; single-strand DNA-binding protein
       K03629  recF; DNA replication and repair protein RecF
       K03584  recO; DNA repair protein RecO (recombination protein O)
       K06187  recR; recombination protein RecR
       K03553  recA; recombination protein RecA
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K03550  ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12]
       K03551  ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12]
       K01159  ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.22.4]
       K03655  recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12]
       K03582  recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
       K03583  recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
       K03581  recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K04066  priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:3.6.4.-]
       K02686  priB; primosomal replication protein N
       K04067  priC; primosomal replication protein N''
       K02317  dnaT; DNA replication protein DnaT
       K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
       K10865  MRE11; double-strand break repair protein MRE11
       K10868  XRS2; DNA repair protein XRS2
       K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
       K10957  RAD55; DNA repair protein RAD55
       K10958  RAD57; DNA repair protein RAD57
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K04482  RAD51; DNA repair protein RAD51
       K10873  RAD52; DNA repair and recombination protein RAD52
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K10881  SHFM1, DSS1; 26 proteasome complex subunit DSS1
       K10869  RAD51L1, RAD51B; RAD51-like protein 1
       K10870  RAD51L2, RAD51C; RAD51-like protein 2
       K10871  RAD51L3, RAD51D; RAD51-like protein 3
       K10879  XRCC2; DNA-repair protein XRCC2
       K10880  XRCC3; DNA-repair protein XRCC3
       K10959  RAD59; DNA repair protein RAD59
       K10875  RAD54L, RAD54; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-]
       K10877  RAD54B; DNA repair and recombination protein RAD54B [EC:3.6.4.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:3.6.4.12]
       K03165  TOP3; DNA topoisomerase III [EC:5.99.1.2]
       K08991  MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
       K10882  EME1, MMS4; crossover junction endonuclease EME1 [EC:3.1.22.-]
     03450 Non-homologous end-joining [PATH:ko03450]
     03460 Fanconi anemia pathway [PATH:ko03460]
     03400 DNA repair and recombination proteins [BR:ko03400]
 
   RNA family
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06724  NRP1; neuropilin 1
       K06527  VCAM1; vascular cell adhesion molecule 1
       K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
       K06451  CD3E; T-cell surface glycoprotein CD3 epsilon chain
       K06452  CD3G; T-cell surface glycoprotein CD3 gamma chain
       K06490  ICAM1; intercellular adhesion molecule 1
       K05718  ITGAL; integrin alpha L
       K06464  ITGB2; integrin beta 2
       K06271  TLN; talin
       K04377  MYC; Myc proto-oncogene protein
       K08874  TRRAP; transformation/transcription domain-associated protein
       K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
       K10151  CCND2; cyclin D2
       K15304  RANBP3; Ran-binding protein 3
       K07936  RAN; GTP-binding nuclear protein Ran
       K14290  XPO1, CRM1; exportin-1
       K06751  MHC1; major histocompatibility complex, class I
       K08057  CALR; calreticulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K08054  CANX; calnexin
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05770  BZRP; benzodiazapine receptor
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
       K06635  PTTG; securin
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04802  PCNA; proliferating cell nuclear antigen
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04503  CCND1; cyclin D1
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K04690  FZDN, fz3; frizzled
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02085  APC; adenomatosis polyposis coli protein
       K12076  DLG1; disks large protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04448  JUN; transcription factor AP-1
       K15307  GPS2; G protein pathway suppressor 2
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K05429  IL2; interleukin 2
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05433  IL15; interleukin 15
       K05074  IL15RA; interleukin 15 receptor alpha
       K05405  IL6; interleukin 6
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K15308  TTP; tristetraprolin
       K08065  NFYB; nuclear transcription Y subunit beta
       K06752  MHC2; major histocompatibility complex, class II
       K04378  SRF; serum response factor
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09438  SPI1; transcription factor PU.1
       K02678  ETS, pnt; c-ets proto-oncogene protein
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04379  FOS; proto-oncogene protein c-fos
       K09203  EGR1; early growth response protein 1
       K12496  EGR2; early growth response protein 2
       K04502  FOSL1; fos-like antigen 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09052  CREM; cAMP response element modulator
       K09053  ATF1; activating transcription factor 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K09032  ATF3, LRF1; activating transcription factor 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09027  XBP1; X box-binding protein 1
       K15309  CRTC1, TORC1; CREB-regulated transcription coactivator 1
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16334  CRTC3, TORC3; CREB-regulated transcription coactivator 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09063  TCF3, E2A; transcription factor E2-alpha
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K09420  MYB; myb proto-oncogene protein
       K09421  MYBL; myb-related protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K15310  TP53INP1; tumor protein p53-inducible nuclear protein 1
       K09341  MSX; homeobox protein MSX
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05168 Herpes simplex infection [PATH:ko05168]
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: October 29, 2014