KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
       K05849  SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04144  DRD1; dopamine receptor D1
       K05840  DRD5; dopamine receptor D5
       K04150  HRH2; histamine receptor H2
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04161  HTR5; 5-hydroxytryptamine receptor 5
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04633  GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05852  PLN; phospholamban
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K16059  STIM1; stromal interaction molecule 1
       K18196  STIM2; stromal interaction molecule 2
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K16057  ORAI2; calcium release-activated calcium channel protein 2
       K16058  ORAI3; calcium release-activated calcium channel protein 3
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
       K05215  P2RX1; P2X purinoceptor 1
       K05216  P2RX2; P2X purinoceptor 2
       K05217  P2RX3; P2X purinoceptor 3
       K05218  P2RX4; P2X purinoceptor 4
       K05219  P2RX5; P2X purinoceptor 5
       K05220  P2RX7; P2X purinoceptor 7
       K05221  P2RX6, P2RXL1; P2X purinoceptor 6
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K04322  CYSLTR1; cysteinyl leukotriene receptor 1
       K04323  CYSLTR2; cysteinyl leukotriene receptor 2
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04166  AGTR1; angiotensin II receptor type 1
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K04169  GRPR; gastrin-releasing peptide receptor
       K04149  HRH1; histamine receptor H1
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K04211  NTSR1; neurotensin receptor 1
       K04229  OXTR; oxytocin receptor
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04297  LTB4R2; leukotriene B4 receptor 2
       K04279  PTAFR; platelet-activating factor receptor
       K04258  PTGER1; prostaglandin E receptor 1
       K04260  PTGER3; prostaglandin E receptor 3
       K04262  PTGFR; prostaglandin F receptor
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04222  TACR1; tachykinin receptor 1
       K04223  TACR2; tachykinin receptor 2
       K04224  TACR3; tachykinin receptor 3
       K04264  TBXA2R; thromboxane A2 receptor
       K04282  TRHR; thyrotropin-releasing hormone receptor
       K04194  CCKAR; cholecystokinin A receptor
       K04195  CCKBR; cholecystokinin B receptor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04636  GNA14; guanine nucleotide-binding protein subunit alpha-14
       K04637  GNA15; guanine nucleotide-binding protein subunit alpha-15
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K06856  IGH; immunoglobulin heavy chain
       K05857  PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K05865  TNNC1; troponin C, slow skeletal and cardiac muscles
       K12042  TNNC2; troponin C, skeletal muscle
       K02183  CALM; calmodulin
       K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
       K07190  PHKA_B; phosphorylase kinase alpha/beta subunit
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K13755  PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K00911  E2.7.1.127, ITPK; 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
       K04166  AGTR1; angiotensin II receptor type 1
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04138  ADRA2A; adrenergic receptor alpha-2A
       K04139  ADRA2B; adrenergic receptor alpha-2B
       K04140  ADRA2C; adrenergic receptor alpha-2C
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K04969  TRPC6; transient receptor potential cation channel subfamily C member 6
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K09260  MEF2A; MADS-box transcription enhancer factor 2A
       K09261  MEF2B; MADS-box transcription enhancer factor 2B
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K09262  MEF2D; MADS-box transcription enhancer factor 2D
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K04378  SRF; serum response factor
       K09183  GATA4; GATA-binding protein 4
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K05849  SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K18154  RGS2; regulator of G-protein signaling 2
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K05852  PLN; phospholamban
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12755  MYL9; myosin regulatory light chain 9
       K04948  CNGA1; cyclic nucleotide gated channel alpha 1
       K04952  CNGB1; cyclic nucleotide gated channel beta 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13762  PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K03916  BDKRB2; bradykinin receptor B2
       K04213  OPRD1; delta-type opioid receptor
       K04265  ADORA1; adenosine A1 receptor
       K04268  ADORA3; adenosine A3 receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K05001  KCNJ8; potassium inwardly-rectifying channel subfamily J member 8
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02158  BAD; BCL2-antagonist of cell death
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K08272  CAB39, MO25; calcium binding protein 39
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K01103  PFKFB; 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K07292  NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K04503  CCND1; cyclin D1
       K06627  CCNA; cyclin A
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K00021  HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
       K00507  SCD, desC; stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1]
       K01578  MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K18341  TBC1D1; TBC1 domain family member 1
       K07877  RAB2A; Ras-related protein Rab-2A
       K07901  RAB8A, MEL; Ras-related protein Rab-8A
       K07903  RAB10; Ras-related protein Rab-10
       K07905  RAB11B; Ras-related protein Rab-11B
       K07881  RAB14; Ras-related protein Rab-14
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K06259  CD36; CD36 antigen
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07207  TSC2; tuberous sclerosis 2
       K07206  TSC1; tuberous sclerosis 1
       K07208  RHEB; Ras homolog enriched in brain
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
     04030 G protein-coupled receptors [BR:ko04030]
     01020 Enzyme-linked receptors [BR:ko01020]
     04050 Cytokine receptors [BR:ko04050]
     03310 Nuclear receptors [BR:ko03310]
     04040 Ion channels [BR:ko04040]
     04031 GTP-binding proteins [BR:ko04031]
     04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04132  CHRM4; muscarinic acetylcholine receptor M4
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K04134  CHRMN; muscarinic acetylcholine receptor
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04138  ADRA2A; adrenergic receptor alpha-2A
       K04139  ADRA2B; adrenergic receptor alpha-2B
       K04140  ADRA2C; adrenergic receptor alpha-2C
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04144  DRD1; dopamine receptor D1
       K04145  DRD2; dopamine receptor D2
       K04146  DRD3; dopamine receptor D3
       K04147  DRD4; dopamine receptor D4
       K05840  DRD5; dopamine receptor D5
       K04148  DRD1N, DopR; dopamine D1-like receptor
       K14049  DRD2N; dopamine D2-like receptor
       K04149  HRH1; histamine receptor H1
       K04150  HRH2; histamine receptor H2
       K04151  HRH3; histamine receptor H3
       K04152  HRH4; histamine receptor H4
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04161  HTR5; 5-hydroxytryptamine receptor 5
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K05051  TAAR; trace amine associated receptor
       K04166  AGTR1; angiotensin II receptor type 1
       K04167  AGTR2; angiotensin II receptor type 2
       K05223  NMB; neuromedin B
       K05224  GRP; gastrin-releasing peptide
       K04168  NMBR; neuromedin B receptor
       K04169  GRPR; gastrin-releasing peptide receptor
       K04170  BRS3; bombesin-like receptor 3
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04010  C5AR1; C5a anaphylatoxin chemotactic receptor
       K04009  C3AR1; C3a anaphylatoxin chemotactic receptor
       K04171  GPR77; G protein-coupled receptor 77
       K04172  FPR1; formyl peptide receptor 1
       K04173  FPRL; formyl peptide receptor-like
       K05225  APLN; apelin
       K04174  APLNR; apelin receptor
       K05226  CCK; cholecystokinin
       K04194  CCKAR; cholecystokinin A receptor
       K04195  CCKBR; cholecystokinin B receptor
       K04196  CCKLR; cholecystokinin-like receptor
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K05228  POMC; proopiomelanocortin
       K05231  AGRP; agouti related protein
       K04199  MC1R; melanocortin 1 receptor
       K04200  MC2R; melanocortin 2 receptor
       K04201  MC3R; melanocortin 3 receptor
       K04202  MC4R; melanocortin 4 receptor
       K04203  MC5R; melanocortin 5 receptor
       K05232  NPY; neuropeptide Y
       K04204  NPY1R; neuropeptide Y receptor type 1
       K04205  NPY2R; neuropeptide Y receptor type 2
       K04206  NPY4R; neuropeptide Y receptor type 4
       K04207  NPY5R; neuropeptide Y receptor type 5
       K04208  NPY6R; neuropeptide Y receptor type 6
       K04209  NPYNR; neuropeptide Y receptor, invertebrate
       K04210  GPR83, GPR72; G protein-coupled receptor 83
       K05233  PYY; peptide YY
       K05234  PPY; pancreatic polypeptide
       K05235  NTS; neurotensin
       K05236  COPA; coatomer protein complex, subunit alpha (xenin)
       K04211  NTSR1; neurotensin receptor 1
       K04212  NTSR2; neurotensin receptor 2
       K04213  OPRD1; delta-type opioid receptor
       K04214  OPRK1; kappa-type opioid receptor
       K04215  OPRM1; mu-type opioid receptor
       K04216  OPRL1; nociceptin receptor
       K05237  SST; somatostatin
       K05238  CORT; cortistatin
       K04217  SSTR1; somatostatin receptor 1
       K04218  SSTR2; somatostatin receptor 2
       K04219  SSTR3; somatostatin receptor 3
       K04220  SSTR4; somatostatin receptor 4
       K04221  SSTR5; somatostatin receptor 5
       K05239  TAC1; tachykinin 1
       K05240  TAC2_3; tachykinin 2/3
       K05241  TAC4; tachykinin 4
       K04222  TACR1; tachykinin receptor 1
       K04223  TACR2; tachykinin receptor 2
       K04224  TACR3; tachykinin receptor 3
       K04225  TAKR; tachykinin-like receptor
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04228  AVPR2; arginine vasopressin receptor 2
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K05244  GAL; galanin
       K04230  GALR1; galanin receptor 1
       K04231  GALR2; galanin receptor 2
       K04232  GALR3; galanin receptor 3
       K04233  GALRN, AR; allatostatin receptor
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K01319  CTSG; cathepsin G [EC:3.4.21.20]
       K01352  GZMA; granzyme A [EC:3.4.21.78]
       K01315  PLG; plasminogen [EC:3.4.21.7]
       K01312  PRSS; trypsin [EC:3.4.21.4]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
       K04235  F2RL2, PAR3; coagulation factor II (thrombin) receptor-like 2
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04237  PARD3; partitioning defective protein 3
       K05246  HCRT; hypocretin (orexin) neuropeptide
       K04238  HCRTR1; hypocretin (orexin) receptor 1
       K04239  HCRTR2; hypocretin (orexin) receptor 2
       K05247  NPFF; neuropeptide FF-amide peptide
       K04240  NPFFR1; neuropeptide FF receptor 1
       K08375  NPFFR2; neuropeptide FF receptor 2
       K05248  UTS2; urotensin 2
       K04241  UTS2R; urotensin 2 receptor
       K05249  NMU; neuromedin U
       K05052  NMUR1; neuromedin U receptor 1
       K05053  NMUR2; neuromedin U receptor 2
       K04320  MCHR1; melanin-concentrating hormone receptor 1
       K05054  MCHR2; melanin-concentrating hormone receptor 2
       K05250  FSH; follicle stimulating hormone
       K04247  FSHR; follicle stimulating hormone receptor
       K05251  TSHB; thyroid stimulating hormone, beta
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K04249  TSHR; thyroid stimulating hormone receptor
       K04332  PTGDR; prostaglandin D2 receptor
       K04258  PTGER1; prostaglandin E receptor 1
       K04259  PTGER2; prostaglandin E receptor 2
       K04260  PTGER3; prostaglandin E receptor 3
       K04261  PTGER4; prostaglandin E receptor 4
       K04262  PTGFR; prostaglandin F receptor
       K04263  PTGIR; prostacyclin receptor
       K04264  TBXA2R; thromboxane A2 receptor
       K04265  ADORA1; adenosine A1 receptor
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04268  ADORA3; adenosine A3 receptor
       K04269  P2RY2; purinergic receptor P2Y, G protein-coupled, 2
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04271  P2RY4; pyrimidinergic receptor P2Y, G protein-coupled, 4
       K04272  P2RY6; pyrimidinergic receptor P2Y, G protein-coupled, 6
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04274  P2RY10; purinergic receptor P2Y, G protein-coupled, 10
       K04299  P2RY14; purinergic receptor P2Y, G protein-coupled, 14
       K08386  P2RY8; purinergic receptor P2Y, G protein-coupled, 8
       K08387  P2RY11; purinergic receptor P2Y, G protein-coupled, 11
       K08388  P2RY13; purinergic receptor P2Y, G protein-coupled, 13
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K04276  GPR35; G protein-coupled receptor 35
       K04277  CNR1; cannabinoid receptor 1
       K04278  CNR2; cannabinoid receptor 2 (macrophage)
       K04279  PTAFR; platelet-activating factor receptor
       K05252  GNRH; gonadotropin-releasing hormone
       K04280  GNRHR; gonadotropin-releasing hormone receptor
       K05253  TRH; thyrotropin-releasing hormone
       K04282  TRHR; thyrotropin-releasing hormone receptor
       K05254  GHRL; ghrelin
       K04284  GHSR; growth hormone secretagogue receptor
       K08374  KISS1R; KISS1 receptor
       K04285  MTNR1A; melatonin receptor type 1A
       K04286  MTNR1B; melatonin receptor type 1B
       K04287  GPR50; G protein-coupled receptor 50
       K04288  S1PR1, EDG1; sphingosine 1-phosphate receptor 1
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04290  S1PR3, EDG3; sphingosine 1-phosphate receptor 3
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2
       K04293  S1PR4, EDG6; sphingosine 1-phosphate receptor 4
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04295  S1PR5, EDG8; sphingosine 1-phosphate receptor 5
       K04296  LTB4R1; leukotriene B4 receptor 1
       K04297  LTB4R2; leukotriene B4 receptor 2
       K04303  MAS1; MAS1 oncogene
       K04306  LGR7; leucine-rich repeat-containing G protein-coupled receptor 7
       K04307  LGR8; leucine-rich repeat-containing G protein-coupled receptor 8
       K04308  LGR5, GPR49; leucine-rich repeat-containing G protein-coupled receptor 5
       K04309  LGR4, GPR48; leucine-rich repeat-containing G protein-coupled receptor 4
       K04322  CYSLTR1; cysteinyl leukotriene receptor 1
       K04323  CYSLTR2; cysteinyl leukotriene receptor 2
       K04576  CALCR; calcitonin receptor
       K04577  CALCRL; calcitonin receptor-like
       K05256  CRH; corticotropin-releasing hormone
       K05257  UCN2_3; urocortin 2/3
       K04578  CRHR1; corticotropin releasing hormone receptor 1
       K04579  CRHR2; corticotropin releasing hormone receptor 2
       K05258  GIP; gastric inhibitory polypeptide
       K04580  GIPR; gastric inhibitory polypeptide receptor
       K05259  GCG; glucagon
       K04581  GLP1R; glucagon-like peptide 1 receptor
       K04582  GLP2R; glucagon-like peptide 2 receptor
       K04583  GCGR; glucagon receptor
       K05260  GHRH; growth hormone-releasing hormone
       K04584  GHRHR; growth hormone releasing hormone receptor
       K05261  PTH; parathyroid hormone
       K04585  PTHR1; parathyroid hormone receptor 1
       K04586  PTHR2; parathyroid hormone receptor 2
       K05262  ADCYAP; adenylate cyclase activating polypeptide
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K05263  SCT; secretin
       K04588  SCTR; secretin receptor
       K05264  VIP; vasoactive intestinal peptide
       K04589  VIPR1; vasoactive intestinal peptide receptor 1
       K04590  VIPR2; vasoactive intestinal peptide receptor 2
       K04603  GRM1; metabotropic glutamate receptor 1
       K04605  GRM2_3; metabotropic glutamate receptor 2/3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04604  GRM5; metabotropic glutamate receptor 5
       K04608  GRM6_7_8; metabotropic glutamate receptor 6/7/8
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04617  GPR156, GABABL; gamma-aminobutyric acid type B receptor-like
       K05265  MLN; motilin
       K05266  MLNR; motilin receptor
       K05267  NPB; preproneuropeptide B
       K05268  NPBWR1; neuropeptides B/W receptor 1
       K08377  NPBWR2; neuropeptides B/W receptor 2
       K05269  PRH; Prolactin-releasing peptide
       K04314  PRLHR, GPR10; prolactin releasing hormone receptor
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K05175  GABRA; gamma-aminobutyric acid receptor subunit alpha
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K05184  GABRD; gamma-aminobutyric acid receptor subunit delta
       K05185  GABRE; gamma-aminobutyric acid receptor subunit epsilon
       K05186  GABRG; gmma-aminobutyric acid receptor subunit gamma
       K05189  GABRP; gamma-aminobutyric acid receptor subunit pi
       K05190  GABRR; gamma-aminobutyric acid receptor subunit rho
       K05192  GABRQ; gamma-aminobutyric acid receptor subunit theta
       K04803  CHRNA1; nicotinic acetylcholine receptor alpha-1
       K04804  CHRNA2; nicotinic acetylcholine receptor alpha-2
       K04805  CHRNA3; nicotinic acetylcholine receptor alpha-3
       K04806  CHRNA4; nicotinic acetylcholine receptor alpha-4
       K04807  CHRNA5; nicotinic acetylcholine receptor alpha-5
       K04808  CHRNA6; nicotinic acetylcholine receptor alpha-6
       K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
       K04810  CHRNA9; nicotinic acetylcholine receptor alpha-9
       K04811  CHRNA10; nicotinic acetylcholine receptor alpha-10
       K04812  CHRNB1; nicotinic acetylcholine receptor beta-1
       K04813  CHRNB2; nicotinic acetylcholine receptor beta-2
       K04814  CHRNB3; nicotinic acetylcholine receptor beta-3
       K04815  CHRNB4; nicotinic acetylcholine receptor beta-4
       K04816  CHRND; nicotinic acetylcholine receptor delta
       K04817  CHRNE; nicotinic acetylcholine receptor epsilon
       K04818  CHRNG; nicotinic acetylcholine receptor gamma
       K05215  P2RX1; P2X purinoceptor 1
       K05216  P2RX2; P2X purinoceptor 2
       K05217  P2RX3; P2X purinoceptor 3
       K05218  P2RX4; P2X purinoceptor 4
       K05219  P2RX5; P2X purinoceptor 5
       K05220  P2RX7; P2X purinoceptor 7
       K05221  P2RX6, P2RXL1; P2X purinoceptor 6
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K08521  LHB; luteinizing hormone beta polypeptide
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05201  GRIK1; glutamate receptor, ionotropic kainate 1
       K05202  GRIK2; glutamate receptor, ionotropic kainate 2
       K05203  GRIK3; glutamate receptor, ionotropic kainate 3
       K05204  GRIK4; glutamate receptor, ionotropic kainate 4
       K05205  GRIK5; glutamate receptor, ionotropic kainate 5
       K05206  GRID1; glutamate receptor delta-1 subunit
       K05207  GRID2; glutamate receptor delta-2 subunit
       K05193  GLRA1; glycine receptor alpha-1
       K05194  GLRA2; glycine receptor alpha-2
       K05195  GLRA3; glycine receptor alpha-3
       K05196  GLRB; glycine receptor beta
       K05222  TRPV1; transient receptor potential cation channel subfamily V member 1
       K05770  BZRP; benzodiazapine receptor
       K05771  NR3C1, GR; glucocorticoid receptor
       K05438  GH; growth hormone
       K05080  GHR; growth hormone receptor
       K05547  NR1A1, THRA; thyroid hormone receptor alpha
       K08362  NR1A2, THRB; thyroid hormone receptor beta
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K05439  PRL; prolactin
       K05081  PRLR; prolactin receptor
     04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
     04052 Cytokines [BR:ko04052]
     04512 ECM-receptor interaction [PATH:ko04512]
     04514 Cell adhesion molecules (CAMs) [PATH:ko04514]
     04516 Cell adhesion molecules and their ligands [BR:ko04516]
     04090 CD Molecules [BR:ko04090]
     04091 Lectins [BR:ko04091]
     02042 Bacterial toxins [BR:ko02042]
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
 
   Circulatory system
     04260 Cardiac muscle contraction [PATH:ko04260]
     04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K04926  KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
       K04894  KCNE1; potassium voltage-gated channel Isk-related subfamily E member 1
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K04838  SCN5A; voltage-gated sodium channel type V alpha
       K04839  SCN7A, SCN6A; voltage-gated sodium channel type VII alpha
       K04845  SCN1B; voltage-gated sodium channel type I beta
       K04848  SCN4B; voltage-gated sodium channel type IV beta
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04962  RYR2; ryanodine receptor 2
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K05865  TNNC1; troponin C, slow skeletal and cardiac muscles
       K12044  TNNI3; troponin I, cardiac muscle
       K12045  TNNT2; troponin T, cardiac muscle
       K10373  TPM1; tropomyosin 1
       K10374  TPM2; tropomyosin 2
       K09290  TPM3; tropomyosin 3
       K10375  TPM4; tropomyosin 4
       K12314  ACTC1; actin, alpha cardiac muscle
       K17751  MYH6_7; myosin heavy chain 6/7
       K10351  MYL2; myosin regulatory light chain 2
       K12749  MYL3; myosin light chain 3
       K12750  MYL4; myosin light chain 4
       K05852  PLN; phospholamban
       K04166  AGTR1; angiotensin II receptor type 1
       K04167  AGTR2; angiotensin II receptor type 2
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K08050  PPP1R1A; protein phosphatase 1 regulatory subunit 1A
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K09052  CREM; cAMP response element modulator
       K02161  BCL2; apoptosis regulator BCL-2
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
     04270 Vascular smooth muscle contraction [PATH:ko04270]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K09821  AGT; angiotensinogen
       K04166  AGTR1; angiotensin II receptor type 1
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K17687  CYP4A11; alkane 1-monooxygenase [EC:1.14.15.3]
       K17688  CYP4A22; alkane 1-monooxygenase [EC:1.14.15.3]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12327  CALD1; caldesmon
       K12313  ACTA2; actin, aortic smooth muscle
       K12315  ACTG2; actin, gamma-enteric smooth muscle
       K12328  PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04263  PTGIR; prostacyclin receptor
       K12332  CALCA; calcitonin
       K12333  ADM; adrenomedullin
       K04577  CALCRL; calcitonin receptor-like
       K08447  RAMP1; receptor activity modifying protein 1
       K08448  RAMP2; receptor activity modifying protein 2
       K08449  RAMP3; receptor activity modifying protein 3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12334  NPPA; natriuretic peptide A
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12336  NPPC; natriuretic peptide C
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
 
   Digestive system
     04970 Salivary secretion [PATH:ko04970]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K13504  VAMP2; vesicle-associated membrane protein 2
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04963  RYR3; ryanodine receptor 3
       K02183  CALM; calmodulin
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K18152  BST1; ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
       K13879  BEST2, VMD2L1; bestrophin-2
       K09867  AQP5; aquaporin-5
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
       K04945  KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K13855  SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K04975  TRPV6; transient receptor potential cation channel subfamily V member 6
       K13908  MUC5B, MG1; mucin-5B
       K13909  MUC7, MG2; mucin-7
       K13910  PRH1_2; salivary acidic proline-rich phosphoprotein 1/2
       K13911  PRB1_2; basic salivary proline-rich protein 1/2
       K13912  DMBT1; deleted in malignant brain tumors 1 protein
       K13897  CST1; cystatin-SN
       K13898  CST2; cystatin-SA
       K13899  CST3; cystatin-C
       K13900  CST4; cystatin-S
       K13901  CST5; cystatin-D
       K13913  HTN; histatin
       K13914  STATH; statherin
       K13915  LYZ; lysozyme C [EC:3.2.1.17]
       K12550  LPO; lactoperoxidase [EC:1.11.1.7]
       K13916  CAMP, LL37; cathelicidin antimicrobial peptide
     04971 Gastric acid secretion [PATH:ko04971]
     04972 Pancreatic secretion [PATH:ko04972]
     04976 Bile secretion [PATH:ko04976]
     04973 Carbohydrate digestion and absorption [PATH:ko04973]
     04974 Protein digestion and absorption [PATH:ko04974]
     04975 Fat digestion and absorption [PATH:ko04975]
     04977 Vitamin digestion and absorption [PATH:ko04977]
     04978 Mineral absorption [PATH:ko04978]
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases

[ BRITE | KEGG2 | KEGG ]
Last updated: September 16, 2014