KEGG Orthology (KO)

[ Brite menu | Organism menu | Download htext ]
    

1st Level  2nd Level  3rd Level  4th Level 

 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K05315  CACNA1N; voltage-dependent calcium channel alpha 1, invertebrate
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K05316  CACNA2DN; voltage-dependent calcium channel alpha-2/delta, invertebrate
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K05317  CACNBN; voltage-dependent calcium channel beta, invertebrate
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04370  MP1, MAP2K1IP1; mitogen-activated protein kinase kinase 1 interacting protein 1
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04377  MYC; Myc proto-oncogene protein
       K04378  SRF; serum response factor
       K04379  FOS; proto-oncogene protein c-fos
       K04380  MAPT, TAU; microtubule-associated protein tau
       K04381  STMN1; stathmin
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04391  CD14; CD14 antigen
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03173  TRAF2; TNF receptor-associated factor 2
       K02308  DAXX; death-associated protein 6
       K03175  TRAF6; TNF receptor-associated factor 6
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04405  ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
       K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
       K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
       K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K04411  STK4, MST1; serine/threonine kinase 4
       K04412  STK3, MST2; serine/threonine kinase 3
       K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
       K04435  MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
       K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
       K04437  FLNA; filamin
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04439  ARRB; beta-arrestin
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  MSK2, RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04451  TP53, P53; tumor protein p53
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K04453  MAX; Max protein
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04455  HSPB1; heat shock protein beta-1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K09253  RELB; transcription factor RelB
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
     02030 Bacterial chemotaxis [PATH:ko02030]
     02035 Bacterial motility proteins [BR:ko02035]
     02040 Flagellar assembly [PATH:ko02040]
     04810 Regulation of actin cytoskeleton [PATH:ko04810]
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04391  CD14; CD14 antigen
       K04526  INS; insulin
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05086  INSRR; insulin receptor-related receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05717  FN1; fibronectin 1
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05718  ITGAL; integrin alpha L
       K06461  ITGAM; integrin alpha M
       K06462  ITGAX; integrin alpha X
       K06594  ITGAD; integrin alpha D
       K06524  ITGAE; integrin alpha E
       K05719  ITGB1; integrin beta 1
       K06464  ITGB2; integrin beta 2
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04132  CHRM4; muscarinic acetylcholine receptor M4
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K05720  FGD1; FYVE, RhoGEF and PH domain containing 1
       K05722  FGD3; FYVE, RhoGEF and PH domain containing 3
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K04438  CRK, CRKII; proto-oncogene C-crk
       K13708  DOCK1; dedicator of cytokinesis protein 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K05729  ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K05730  VAV; guanine nucleotide exchange factor VAV
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K05732  GRLF1; glucocorticoid receptor DNA-binding factor 1
       K04513  RHOA; Ras homolog gene family, member A
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K05736  PAK7; p21-activated kinase 7 [EC:2.7.11.1]
       K13710  ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
       K05737  GIT1; G protein-coupled receptor kinase interactor 1
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K05740  DIAPH1; diaphanous 1
       K05741  DIAPH2; diaphanous 2
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K00889  E2.7.1.68, PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K00920  E2.7.1.149, PIP4K; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
       K00921  PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
       K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
       K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
       K05745  DIAPH3, DRF3; diaphanous 3
       K05627  BAIAP2, IRSP53; BAI1-associated protein 2
       K05746  ENAH, MENA; enabled
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K05748  WASF2; WAS protein family, member 2
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K05750  NCKAP1, NAP125; NCK-associated protein 1
       K05751  ABI2; abl interactor 2
       K05752  C3ORF10, HSPC300; chromosome 3 open reading frame 10
       K05753  WASF1; WAS protein family, member 1
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K05692  ACTB_G1; actin beta/gamma 1
       K05759  PFN; profilin
       K05760  PXN; paxillin
       K08007  VIL2; villin 2 (ezrin)
       K05762  RDX; radixin
       K05763  MSN; moesin
       K05764  TMSB4; thymosin, beta 4
       K05765  CFL; cofilin
       K05766  SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
       K05700  VCL; vinculin
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K05767  IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
       K05768  GSN; gelsolin
       K05699  ACTN; actinin alpha
       K02085  APC; adenomatosis polyposis coli protein
       K05769  ARHGEF4, ASEF; Rho guanine nucleotide exchange factor 4
     04812 Cytoskeleton proteins [BR:ko04812]
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K08556  NR3C3, PGR; progesterone receptor
       K08557  NR3C4, AR; androgen receptor
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K11481  AURKA; aurora kinase A [EC:2.7.11.1]
       K02602  ORB; oo18 RNA-binding protein
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K08694  SPDY, RINGO; speedy
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K08836  SLK; STE20-like kinase [EC:2.7.11.1]
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K13056  C3H-4; CCCH zinc finger protein C3H-4
       K03868  RBX1, ROC1; RING-box protein 1
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K10292  FBXO5, EMI1; F-box protein 5
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K10318  FBXO43, EMI2; F-box protein 43
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K13054  REC8L; meiotic recombination protein REC8, animal type
       K13055  STAG3; cohesin complex subunit SA-3
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K06626  CCNE; cyclin E
       K11580  SGOL1; shugoshin-like 1
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
     04210 Apoptosis [PATH:ko04210]
     04115 p53 signaling pathway [PATH:ko04115]
 
   Cell communication
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
       K08556  NR3C3, PGR; progesterone receptor
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02602  ORB; oo18 RNA-binding protein
       K08694  SPDY, RINGO; speedy
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K06627  CCNA; cyclin A
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K05868  CCNB; cyclin B
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K07827  KRAS, KRAS2; GTPase KRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases

[ BRITE | KEGG2 | KEGG ]
Last updated: July 28, 2014