KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K05315  CACNA1N; voltage-dependent calcium channel alpha 1, invertebrate
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K05316  CACNA2DN; voltage-dependent calcium channel alpha-2/delta, invertebrate
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K05317  CACNBN; voltage-dependent calcium channel beta, invertebrate
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04370  MP1, MAP2K1IP1; mitogen-activated protein kinase kinase 1 interacting protein 1
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04377  MYC; Myc proto-oncogene protein
       K04378  SRF; serum response factor
       K04379  FOS; proto-oncogene protein c-fos
       K04380  MAPT, TAU; microtubule-associated protein tau
       K04381  STMN1; stathmin
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04391  CD14; CD14 antigen
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03173  TRAF2; TNF receptor-associated factor 2
       K02308  DAXX; death-associated protein 6
       K03175  TRAF6; TNF receptor-associated factor 6
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04405  ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
       K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
       K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
       K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K04411  STK4, MST1; serine/threonine kinase 4
       K04412  STK3, MST2; serine/threonine kinase 3
       K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
       K04435  MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
       K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
       K04437  FLNA; filamin
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04439  ARRB; beta-arrestin
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  MSK2, RPS6KA4; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04451  TP53, P53; tumor protein p53
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K04453  MAX; Max protein
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04455  HSPB1; heat shock protein beta-1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K09253  RELB; transcription factor RelB
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
       K11234  MFAL; mating pheromone alpha-factor
       K11235  MFA; mating pheromone A-factor
       K11213  STE2; pheromone alpha factor receptor
       K04627  STE3; pheromone a factor receptor
       K07972  GNB; guanine nucleotide-binding protein subunit beta, other
       K07973  GNG; guanine nucleotide-binding protein subunit gamma, other
       K04393  CDC42; cell division control protein 42
       K11236  CDC24; cell division control protein 24
       K11237  BEM1; bud emergence protein 1
       K11238  BNI1; cytokinesis protein
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K11228  STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.1]
       K11239  STE5; pheromone-response scaffold protein
       K11226  STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K11240  MSG5; tyrosine-protein phosphatase [EC:3.1.3.48]
       K11241  DIG1; down-regulator of invasive growth 1
       K11242  DIG2; down-regulator of invasive growth 2
       K11215  STE12; transcription factor STE12
       K12412  MCM1; pheromone receptor transcription factor
       K11243  FUS1; nuclear fusion protein
       K06652  FAR1; cyclin-dependent kinase inhibitor FAR1
       K11244  WSC; cell wall integrity and stress response component
       K11245  MID2; mating pheromone-induced death protein 2
       K04513  RHOA; Ras homolog gene family, member A
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K11229  BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.1]
       K08294  MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K09291  TPR; nucleoprotein TPR
       K06649  SWI4; regulatory protein SWI4
       K06648  SWI6; regulatory protein SWI6
       K11246  SHO1; SHO1 osmosensor
       K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
       K11232  YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
       K11233  SSK1; osomolarity two-component system, response regulator SSK1
       K11230  SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
       K11227  PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K01759  GLO1, gloA; lactoylglutathione lyase [EC:4.4.1.5]
       K09448  TEAD; transcriptional enhancer factor
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
 
   Cellular commiunity
     04510 Focal adhesion [PATH:ko04510]
     04520 Adherens junction [PATH:ko04520]
     04530 Tight junction [PATH:ko04530]
     04540 Gap junction [PATH:ko04540]
       K07372  GJA1, CX43; gap junction protein, alpha 1
       K07373  GJD2; gap junction delta-2 protein
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04357  EGF; epidermal growth factor
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K07374  TUBA; tubulin alpha
       K07375  TUBB; tubulin beta
       K08959  CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K05701  TJP1, ZO1; tight junction protein 1
       K04141  ADRB1; adrenergic receptor beta-1
       K04144  DRD1; dopamine receptor D1
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04145  DRD2; dopamine receptor D2
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
       K05252  GNRH; gonadotropin-releasing hormone
       K04280  GNRHR; gonadotropin-releasing hormone receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04393  CDC42; cell division control protein 42
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K08521  LHB; luteinizing hormone beta polypeptide
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K05250  FSH; follicle stimulating hormone
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K07763  MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04375  ELK1; ETS domain-containing protein Elk-1
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04503  CCND1; cyclin D1
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K04977  TRPM2; transient receptor potential cation channel subfamily M member 2
       K04996  KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
       K05005  KCNJ12; potassium inwardly-rectifying channel subfamily J member 12
       K04998  KCNJ4; potassium inwardly-rectifying channel subfamily J member 4
       K05007  KCNJ14; potassium inwardly-rectifying channel subfamily J member 14
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K18154  RGS2; regulator of G-protein signaling 2
       K17901  RCAN1, MCIP1; calcipressin-1
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K08794  CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
     04724 Glutamatergic synapse [PATH:ko04724]
     04727 GABAergic synapse [PATH:ko04727]
     04725 Cholinergic synapse [PATH:ko04725]
     04728 Dopaminergic synapse [PATH:ko04728]
     04726 Serotonergic synapse [PATH:ko04726]
     04720 Long-term potentiation [PATH:ko04720]
     04730 Long-term depression [PATH:ko04730]
     04723 Retrograde endocannabinoid signaling [PATH:ko04723]
     04721 Synaptic vesicle cycle [PATH:ko04721]
     04722 Neurotrophin signaling pathway [PATH:ko04722]
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K12457  NTF4; neurotrophin 4
       K04356  NTF3; neurotrophin 3
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
       K07193  APS, SH2B2; SH2B adapter protein 2
       K12459  SH2B1_3; SH2B adaptor protein 1/3
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K02161  BCL2; apoptosis regulator BCL-2
       K12460  KIDINS220, ARMS; ankyrin repeat-rich membrane spanning protein
       K12461  FRS2; fibroblast growth factor receptor substrate 2
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K09593  GAB1; GRB2-associated-binding protein 1
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K09408  FOXO3; forkhead box protein O3
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K02158  BAD; BCL2-antagonist of cell death
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K16172  IRS1; insulin receptor substrate 1
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K08888  MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K12462  ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
       K04513  RHOA; Ras homolog gene family, member A
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K10148  TP73; tumor protein p73
       K03175  TRAF6; TNF receptor-associated factor 6
       K12458  ZNF274; zinc finger protein 274
       K12463  PRDM4; PR domain zinc finger protein 4
       K12464  MAGED1, NRAGE; melanoma-associated antigen D1
       K12465  NGFRAP1; nerve growth factor receptor-associated protein 1
       K06630  YWHAE; 14-3-3 protein epsilon
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
       K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K12388  SORT1; sortilin
       K04505  PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
       K04522  PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
       K17002  MIR17; microRNA 17
       K17003  MIR18A; microRNA 18a
       K17005  MIR19; microRNA 19
       K17006  MIR20A; microRNA 20a
       K17008  MIR92A; microRNA 92a
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K17010  MIR221; microRNA 221
       K17011  MIR222; microRNA 222
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K16863  MIR21; microRNA 21
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16980  MIRLET7; microRNA let-7
       K17397  MIRLET7C; microRNA let-7c
       K07827  KRAS, KRAS2; GTPase KRas
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K09283  HMGA2; high mobility group AT-hook protein 2
       K17396  MIR107; microRNA 107
       K16986  MIR15A; microRNA 15a
       K16987  MIR15B; microRNA 15b
       K16988  MIR16; microRNA 16
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K06626  CCNE; cyclin E
       K16978  MIR126; microRNA 126
       K04438  CRK, CRKII; proto-oncogene C-crk
       K16972  MIR1; microRNA 1
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K16995  MIR29A; microRNA 29a
       K16996  MIR29B; microRNA 29b
       K16997  MIR29C; microRNA 29c
       K17398  DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
       K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
       K16970  MIR133A; microRNA 133a
       K16971  MIR133B; microRNA 133b
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K02163  BCLW; apoptosis regulator BCL-W
       K16974  MIR145; microRNA 145
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05448  VEGFA; vascular endothelial growth factor A
       K17017  MIR200C; microRNA 200c
       K17018  MIR141; microRNA 141
       K13376  TGFB2; transforming growth factor beta-2
       K17116  MIR183; microRNA 183
       K08007  VIL2; villin 2 (ezrin)
       K16993  MIR125A; microRNA 125a
       K16994  MIR125B; microRNA 125b
       K16865  PDCD4; programmed cell death protein 4
       K17023  MIR143; microRNA 143
       K17131  MIR192; microRNA 192
       K17371  MIR194; microRNA 194
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K17167  MIR215; microRNA 215
       K17366  MIR28; microRNA 28
       K17110  MIR30A_D_E; microRNA 30a/d/e
       K17111  MIR30B; microRNA 30b
       K17040  MIR30C; microRNA 30c
       K10373  TPM1; tropomyosin 1
       K17383  SPRY2; protein sprouty homolog 2
       K02161  BCL2; apoptosis regulator BCL-2
       K10139  SERPINB5; serpin B5
       K17009  MIR155; microRNA 155
       K16975  MIR203; microRNA 203
       K17150  MIR205; microRNA 205
       K09299  ZEB1_2; zinc finger homeobox protein 1/2
       K17112  MIR27A; microRNA 27a
       K17113  MIR27B; microRNA 27b
       K08670  ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
       K07410  CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
       K17183  MIR31; microRNA 31
       K17367  MIR99A; microRNA 99a
       K17041  MIR100; microRNA 100
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07436  CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.13.126]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K10149  TP63; tumor protein p63
       K16976  MIR375; microRNA 375
       K17379  MIR602; microRNA 602
       K09850  RASSF1; Ras association domain-containing protein 1
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K17460  BMF; Bcl-2-modifying factor
       K17042  MIR224; microRNA 224
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K17036  MIR363; microRNA 363
       K17378  MIR494; microRNA 494
       K17380  MIR615; microRNA 615
       K17381  MIR625; microRNA 625
       K17038  MIR25; microRNA 25
       K16982  MIR34A; microRNA 34a
       K17114  MIR96; microRNA 96
       K16864  MIR10A; microRNA 10a
       K17165  MIR23A; microRNA 23a
       K17394  MIR23B; microRNA 23b
       K17395  MIR23C; microRNA 23c
       K17020  MIR122; microRNA 122
       K13863  SLC7A1, ATRC1; solute carrier family 7 (cationic amino acid transporter), member 1
       K10145  CCNG1; cyclin G1
       K17024  MIR150; microRNA 150
       K17001  MIR223; microRNA 223
       K04381  STMN1; stathmin
       K17132  MIR342; microRNA 342
       K17376  MIR423; microRNA 423
       K04692  STAT3; signal transducer and activator of transcription 3
       K04377  MYC; Myc proto-oncogene protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K17119  MIR199B; microRNA 199b
       K17152  MIR324; microRNA 324
       K17137  MIR483; microRNA 483
       K16984  MIR26A; microRNA 26a
       K16985  MIR26B; microRNA 26b
       K17370  MIR152; microRNA 152
       K00558  DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
       K17144  MIR135; microRNA 135
       K02085  APC; adenomatosis polyposis coli protein
       K16172  IRS1; insulin receptor substrate 1
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K17015  MIR200A; microRNA 200a
       K17016  MIR200B; microRNA 200b
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K17461  RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs
       K17126  MIR124; microRNA 124
       K17369  MIR137; microRNA 137
       K17130  MIR128; microRNA 128
       K06620  E2F3; transcription factor E2F3
       K17365  MIR7; microRNA 7
       K07187  IRS2; insulin receptor substrate 2
       K17372  MIR326; microRNA 326
       K02599  NOTCH; Notch
       K11459  PCGF4, BMI1; polycomb group RING finger protein 4
       K17012  MIR146A; microRNA 146a
       K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
       K17025  MIR181A; microRNA 181a
       K17026  MIR181B; microRNA 181b
       K17027  MIR181C; microRNA 181c
       K17028  MIR181D; microRNA 181d
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K17000  MIR373; microRNA 373
       K17175  MIR520; microRNA 520
       K06256  CD44; CD44 antigen
       K16989  MIR103; microRNA 103
       K11592  DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
       K02329  FZD3; frizzled 3
       K06484  ITGA5; integrin alpha 5
       K05762  RDX; radixin
       K04513  RHOA; Ras homolog gene family, member A
       K17148  MIR193B; microRNA 193b
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K17442  ZFPM2, FOG2; zinc finger protein ZFPM2
       K06493  ITGB3; integrin beta 3
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K17033  MIR335; microRNA 335
       K06252  TN; tenascin
       K16973  MIR206; microRNA 206
       K17172  MIR451; microRNA 451
       K05658  ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]
       K17375  MIR345; microRNA 345
       K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
       K17151  MIR214; microRNA 214
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K17035  MIR106B; microRNA 106b
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K17178  MIR210; microRNA 210
       K16857  THBS1; thrombospondin 1
       K17391  IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:6.3.2.19]
       K16977  MIR9; microRNA 9
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K17118  MIR199A; microRNA 199a
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04364  GRB2; growth factor receptor-binding protein 2
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K10127  MDM4, MDMX; protein Mdm4
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K17129  MIR101; microRNA 101
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K17029  MIR195; microRNA 195
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K03099  SOS; son of sevenless
       K06279  SHC1; SHC- transforming protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17368  MIR129; microRNA 129
       K17449  SHC4; SHC- transforming protein 4
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K17039  MIR32; microRNA 32
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K12561  MARCKS; myristoylated alanine-rich C-kinase substrate
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K17377  MIR449A; microRNA 449a
       K11430  EZH2; histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K17373  MIR330; microRNA 330
       K17374  MIR331; microRNA 331
       K17390  CDCA5; sororin
       K17387  KIF23; kinesin family member 23
       K17389  MIR520C; microRNA 520c
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K15379  SLC45A3; solute carrier family 45, member 3
       K07606  VIM; vimentin
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: August 27, 2014