KEGG Orthology (KO)

[ Brite menu | Organism menu | Download htext | Download json ]
    

1st Level  2nd Level  3rd Level  4th Level 

 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22428  FGF19_23; fibroblast growth factor 19/23
       K22429  FGF21; fibroblast growth factor 21
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, CD271; nerve growth factor receptor (TNFR superfamily member 16)
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K09593  GAB1; GRB2-associated-binding protein 1
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
       K07362  LAT; linker for activation of T cells
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K02183  CALM; calmodulin
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07831  MRAS; Ras-related protein M-Ras
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K12380  RASA3; Ras GTPase-activating protein 3
       K17630  RASA4, CAPRI; Ras GTPase-activating protein 4
       K17631  SYNGAP, RASA5; Ras/Rap GTPase-activating protein SynGAP
       K17632  RASAL1; RAS protein activator-like 1
       K17633  RASAL2; RAS protein activator-like 2
       K17634  RASAL3; RAS protein activator-like 3
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K05736  PAK7; p21-activated kinase 7 [EC:2.7.11.1]
       K04513  RHOA; Ras homolog gene family, member A
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02158  BAD; Bcl-2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K12358  FOXO4; forkhead box protein O4
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K05702  AF6, MLLT4; afadin
       K19613  SHOC2, SUR8; leucine-rich repeat protein SHOC2
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K13618  PLA1A; phospholipase A1 member A [EC:3.1.1.-]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K02678  ETS1, pnt; C-ets-1
       K21932  ETS2; C-ets-2
       K10632  BRAP; BRCA1-associated protein [EC:2.3.2.27]
       K14958  KSR1; kinase suppressor of Ras 1
       K18529  KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
       K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K17635  RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1
       K17636  RGL2; ral guanine nucleotide dissociation stimulator-like 2
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K17637  EXOC2, SEC5; exocyst complex component 2
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K09254  REL; c-Rel proto-oncogene protein
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K17638  RIN1; Ras and Rab interactor 1
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K07941  ARF6; ADP-ribosylation factor 6
     04015 Rap1 signaling pathway [PATH:ko04015]
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K07831  MRAS; Ras-related protein M-Ras
       K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
       K17697  DOCK4; dedicator of cytokinesis protein 4
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K02183  CALM; calmodulin
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04172  FPR1; formyl peptide receptor 1
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04357  EGF; epidermal growth factor
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22428  FGF19_23; fibroblast growth factor 19/23
       K22429  FGF21; fibroblast growth factor 21
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, CD271; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05631  AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
       K05629  AIP1; atrophin-1 interacting protein 1
       K06112  MAGI3; membrane-associated guanylate kinase-related
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08020  RAPGEF6, PDZGEF2; Rap guanine nucleotide exchange factor 6
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K07362  LAT; linker for activation of T cells
       K17698  FYB, ADAP; FYN binding protein
       K07361  LCP2; lymphocyte cytosolic protein 2
       K17699  SKAP1, SKAP55; src kinase associated phosphoprotein 1
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K06070  PKD; protein kinase D [EC:2.7.11.13]
       K04145  DRD2; dopamine receptor D2
       K04277  CNR1; cannabinoid receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K17700  RAP1GAP, RAPGAP; RAP1 GTPase activating protein 1
       K17701  SIPA1L1, E6TP1; signal-induced proliferation-associated 1 like protein 1
       K08013  SIPA1; signal-induced proliferation-associated gene 1
       K17702  SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like protein 2
       K17703  SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like protein 3
       K04680  ID1; DNA-binding protein inhibitor ID1
       K16857  THBS1; thrombospondin 1
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K17704  APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
       K06271  TLN; talin
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06493  ITGB3, CD61; integrin beta 3
       K05759  PFN; profilin
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05692  ACTB_G1; actin beta/gamma 1
       K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
       K04513  RHOA; Ras homolog gene family, member A
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06082  FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
       K04393  CDC42; cell division control protein 42
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K04237  PARD3; partitioning defective protein 3
       K06093  PARD6; partitioning defective protein 6
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
       K05702  AF6, MLLT4; afadin
       K05690  CTNND1; catenin (cadherin-associated protein), delta 1
       K17705  KRIT1; Krev interaction trapped protein 1
       K17706  RGS14; regulator of G-protein signaling 14
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K05718  ITGAL, CD11a; integrin alpha L
       K06461  ITGAM, CD11b; integrin alpha M
       K06464  ITGB2, CD18; integrin beta 2
       K05719  ITGB1, CD29; integrin beta 1
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
     04010 MAPK signaling pathway [PATH:ko04010]
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04349  RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
       K12326  RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08052  NF1; neurofibromin 1
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K09784  EREG; epiregulin
       K09782  AREG; amphiregulin
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22428  FGF19_23; fibroblast growth factor 19/23
       K22429  FGF21; fibroblast growth factor 21
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, CD271; nerve growth factor receptor (TNFR superfamily member 16)
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04370  LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04377  MYC; Myc proto-oncogene protein
       K04378  SRF; serum response factor
       K04379  FOS; proto-oncogene protein c-fos
       K04380  MAPT, TAU; microtubule-associated protein tau
       K04381  STMN1; stathmin
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K04391  CD14; monocyte differentiation antigen CD14
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K02308  DAXX; death-associated protein 6
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04405  ECSIT; evolutionarily conserved signaling intermediate in Toll pathway
       K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
       K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
       K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K04411  STK4, MST1; serine/threonine kinase 4
       K04412  STK3, MST2; serine/threonine kinase 3
       K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
       K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
       K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04434  MAPK8IP1, JIP1; mitogen-activated protein kinase 8 interacting protein 1
       K04435  MAPK8IP2, JIP2; mitogen-activated protein kinase 8 interacting protein 2
       K04436  MAPK8IP3, JIP3; mitogen-activated protein kinase 8 interacting protein 3
       K04437  FLNA; filamin
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04439  ARRB; beta-arrestin
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K16510  RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04451  TP53, P53; tumor protein p53
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K04453  MAX; Max protein
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04455  HSPB1; heat shock protein beta-1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04457  PPM1A, PP2CA; protein phosphatase 1A [EC:3.1.3.16]
       K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
       K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
       K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
       K21278  DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
       K04459  DUSP, MKP; dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48]
       K21946  DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
       K18498  DUSP9, MKP4; dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48]
       K20216  DUSP10; dual specificity phosphatase 10 [EC:3.1.3.16 3.1.3.48]
       K17614  DUSP3, VHR; dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48]
       K04460  PPP5C; serine/threonine-protein phosphatase 5 [EC:3.1.3.16]
       K04461  PPM1B, PP2CB; protein phosphatase 1B [EC:3.1.3.16]
       K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K09253  RELB; transcription factor RelB
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04341 Hedgehog signaling pathway - fly [PATH:ko04341]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
     04371 Apelin signaling pathway [PATH:ko04371]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
       K05405  IL6; interleukin 6
       K05055  IL6R, CD126; interleukin 6 receptor
       K04692  STAT3; signal transducer and activator of transcription 3
       K10160  TLR4, CD284; toll-like receptor 4
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04526  INS; insulin
       K04357  EGF; epidermal growth factor
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03868  RBX1, ROC1; RING-box protein 1 [EC:2.3.2.32]
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K21421  NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K16451  TIMP1; metallopeptidase inhibitor 1
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K05437  EPO; erythropoietin
       K14736  TF; transferrin
       K06503  TFRC, CD71; transferrin receptor
       K05448  VEGFA; vascular endothelial growth factor A
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K03982  SERPINE1, PAI1; plasminogen activator inhibitor 1
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K16366  EDN1; endothelin-1
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K00510  HMOX1; heme oxygenase 1 [EC:1.14.14.18]
       K12334  NPPA; natriuretic peptide A
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K12077  PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
       K01689  ENO, eno; enolase [EC:4.2.1.11]
       K01103  PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3  [EC:2.7.1.105 3.1.3.46]
       K02161  BCL2; apoptosis regulator Bcl-2
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K00161  PDHA, pdhA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
       K00162  PDHB, pdhB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
     04068 FoxO signaling pathway [PATH:ko04068]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K11431  SETD7; histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04411  STK4, MST1; serine/threonine kinase 4
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K12358  FOXO4; forkhead box protein O4
       K17847  FOXO6; forkhead box protein O6
       K04603  GRM1; metabotropic glutamate receptor 1
       K15010  HOMER; homer
       K17848  AGAP2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
       K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
       K05405  IL6; interleukin 6
       K05443  IL10, CSIF; interleukin 10
       K04692  STAT3; signal transducer and activator of transcription 3
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K11434  PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
       K09385  FOXG; forkhead box protein G
       K05868  CCNB1; G2/mitotic-specific cyclin-B1
       K21770  CCNB2; G2/mitotic-specific cyclin-B2
       K21771  CCNB3; G2/mitotic-specific cyclin-B3
       K04503  CCND1; G1/S-specific cyclin-D1
       K10151  CCND2; G1/S-specific cyclin-D2
       K10146  CCNG2; cyclin G2
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K06623  CDKN2D, P19, INK4D; cyclin-dependent kinase inhibitor 2D
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K16332  RBL2; retinoblastoma-like protein 2
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K08861  PLK2; polo-like kinase 2 [EC:2.7.11.21]
       K08862  PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
       K08863  PLK4; polo-like kinase 4 [EC:2.7.11.21]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K15618  BCL6; B-cell lymphoma 6 protein
       K15464  BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       K08336  ATG12; ubiquitin-like protein ATG12
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K05072  IL7R, CD127; interleukin 7 receptor
       K17845  KLF2; krueppel-like factor 2
       K04288  S1PR1, EDG1, CD363; sphingosine 1-phosphate receptor 1
       K04293  S1PR4, EDG6; sphingosine 1-phosphate receptor 4
       K10628  RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
       K10988  RAG2; recombination-activating protein 2
       K10305  FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
       K04357  EGF; epidermal growth factor
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05461  KITLG; KIT ligand
       K04526  INS; insulin
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K09593  GAB1; GRB2-associated-binding protein 1
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07831  MRAS; Ras-related protein M-Ras
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04513  RHOA; Ras homolog gene family, member A
       K07937  ARF1; ADP-ribosylation factor 1
       K07941  ARF6; ADP-ribosylation factor 6
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06856  IGH; immunoglobulin heavy chain
       K08089  FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
       K08090  MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
       K07983  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K13509  AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
       K13523  AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
       K19007  AGPAT5; lysophosphatidiate acyltransferase [EC:2.3.1.51]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00889  PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K00901  dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
       K01080  PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
       K05242  AVP; arginine vasopressin
       K10030  IL8, CXCL8; interleukin 8
       K04166  AGTR1; angiotensin II receptor type 1
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04603  GRM1; metabotropic glutamate receptor 1
       K04605  GRM2_3; metabotropic glutamate receptor 2/3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04604  GRM5; metabotropic glutamate receptor 5
       K04608  GRM6_7_8; metabotropic glutamate receptor 6/7/8
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04228  AVPR2; arginine vasopressin receptor 2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04262  PTGFR; prostaglandin F receptor
       K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
       K05050  CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K18441  CYTH; cytohesin
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K01528  DNM; dynamin GTPase [EC:3.6.5.5]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
       K04166  AGTR1; angiotensin II receptor type 1
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04138  ADRA2A; adrenergic receptor alpha-2A
       K04139  ADRA2B; adrenergic receptor alpha-2B
       K04140  ADRA2C; adrenergic receptor alpha-2C
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K04969  TRPC6; transient receptor potential cation channel subfamily C member 6
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K09260  MEF2A; MADS-box transcription enhancer factor 2A
       K09261  MEF2B; MADS-box transcription enhancer factor 2B
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K09262  MEF2D; MADS-box transcription enhancer factor 2D
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K04378  SRF; serum response factor
       K09183  GATA4; GATA-binding protein 4
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K19477  PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3, KCNU1; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K05849  SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K18154  RGS2; regulator of G-protein signaling 2
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K05852  PLN; phospholamban
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12755  MYL9; myosin regulatory light chain 9
       K04948  CNGA1; cyclic nucleotide gated channel alpha 1
       K04952  CNGB1; cyclic nucleotide gated channel beta 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K19021  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
       K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
       K13762  PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K03916  BDKRB2; bradykinin receptor B2
       K04213  OPRD1; delta-type opioid receptor
       K04265  ADORA1; adenosine A1 receptor
       K04268  ADORA3; adenosine A3 receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K05001  KCNJ8; potassium inwardly-rectifying channel subfamily J member 8
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02158  BAD; Bcl-2-antagonist of cell death
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K09784  EREG; epiregulin
       K09782  AREG; amphiregulin
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22428  FGF19_23; fibroblast growth factor 19/23
       K22429  FGF21; fibroblast growth factor 21
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, CD271; nerve growth factor receptor (TNFR superfamily member 16)
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; B-lymphocyte antigen CD19
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K05055  IL6R, CD126; interleukin 6 receptor
       K05071  IL4R, CD124; interleukin 4 receptor
       K05072  IL7R, CD127; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1A; collagen, type I, alpha
       K19719  COL2A; collagen, type II, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K08131  COL9A; collagen, type IX, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1, CD49a; integrin alpha 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06483  ITGA4, CD49d; integrin alpha 4
       K06484  ITGA5, CD49e; integrin alpha 5
       K06485  ITGA6, CD49f; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV, CD51; integrin alpha V
       K05719  ITGB1, CD29; integrin beta 1
       K06493  ITGB3, CD61; integrin beta 3
       K06525  ITGB4, CD104; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K06626  CCNE; G1/S-specific cyclin-E1
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; Bcl-2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator Bcl-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB, C-MYB; transcriptional activator Myb
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
     04152 AMPK signaling pathway [PATH:ko04152]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K08272  CAB39, MO25; calcium binding protein 39
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K05424  LEP; leptin
       K05062  LEPR, CD295; leptin receptor
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K19028  PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
       K19029  PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
       K01103  PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3  [EC:2.7.1.105 3.1.3.46]
       K19030  PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K07292  NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K04503  CCND1; G1/S-specific cyclin-D1
       K06627  CCNA; cyclin-A
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K00021  HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K11262  ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
       K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
       K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
       K01578  MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
       K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
       K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
       K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K18341  TBC1D1; TBC1 domain family member 1
       K07877  RAB2A; Ras-related protein Rab-2A
       K07901  RAB8A, MEL; Ras-related protein Rab-8A
       K07903  RAB10; Ras-related protein Rab-10
       K07905  RAB11B; Ras-related protein Rab-11B
       K07881  RAB14; Ras-related protein Rab-14
       K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K06259  CD36; CD36 antigen
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07207  TSC2; tuberous sclerosis 2
       K07206  TSC1; tuberous sclerosis 1
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
     04150 mTOR signaling pathway [PATH:ko04150]
       K13780  SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
       K06519  SLC3A2, MDU1, CD98; solute carrier family 3, member 2
       K14995  SLC38A9; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9
       K02145  ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:3.6.3.14]
       K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
       K02148  ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
       K02149  ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
       K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
       K02151  ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
       K02152  ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K20397  LAMTOR1; ragulator complex protein LAMTOR1
       K20398  LAMTOR2; ragulator complex protein LAMTOR2
       K04370  LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
       K20399  LAMTOR4; ragulator complex protein LAMTOR4
       K16344  LAMTOR5, HBXIP; ragulator complex protein LAMTOR5
       K09594  FLCN, BHD; folliculin
       K20400  FNIP1; folliculin-interacting protein 1
       K20401  FNIP2; folliculin-interacting protein 2
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K20402  DEPTOR; DEP domain-containing mTOR-interacting protein
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K11137  TELO2, TEL2; telomere length regulation protein
       K20403  TTI1; TELO2-interacting protein 1
       K10421  CLIP1, RSN; CAP-Gly domain-containing linker protein 1
       K20064  GRB10; growth factor receptor-bound protein 10
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K15705  RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K20404  DEPDC5; DEP domain-containing protein 5
       K20405  NPRL2; nitrogen permease regulator 2-like protein
       K20406  NPRL3; nitrogen permease regulator 3-like protein
       K20407  MIOS, MIO; WD repeat-containing protein mio
       K14299  SEH1; nucleoporin SEH1
       K20408  WDR24; WD repeat-containing protein 24
       K20409  WDR59; WD repeat-containing protein 59
       K14004  SEC13; protein transport protein SEC13
       K20394  SESN2; sestrin 2
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K08272  CAB39, MO25; calcium binding protein 39
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K20396  TBC1D7; TBC1 domain family member 7
       K07208  RHEB; Ras homolog enriched in brain
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K04690  FZDN, fz3; frizzled
       K03068  LRP5_6; low density lipoprotein receptor-related protein 5/6
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K16172  IRS1; insulin receptor substrate 1
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K20410  MAPKAP1, SIN1; target of rapamycin complex 2 subunit MAPKAP1
       K08267  RICTOR; rapamycin-insensitive companion of mTOR
       K20411  PRR5; proline-rich protein 5
       K04513  RHOA; Ras homolog gene family, member A
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell growth and death
 
   Cellular community - eukaryotes
     04510 Focal adhesion [PATH:ko04510]
     04520 Adherens junction [PATH:ko04520]
       K06081  PVRL1, CD111; poliovirus receptor-related protein 1
       K06531  PVRL2, CD112; poliovirus receptor-related protein 2
       K06592  PVRL3, CD113; poliovirus receptor-related protein 3
       K06593  PVRL4; poliovirus receptor-related 4
       K04237  PARD3; partitioning defective protein 3
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06082  FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K05627  BAIAP2, IRSP53; BAI1-associated protein 2
       K05753  WASF1; WAS protein family, member 1
       K05748  WASF2; WAS protein family, member 2
       K06083  WASF3; WAS protein family, member 3
       K05702  AF6, MLLT4; afadin
       K06084  LMO7, FBXO20; F-box protein 20
       K06085  SSX2IP, ADIP; synovial sarcoma, X breakpoint 2 interacting protein
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K05699  ACTN1_4; actinin alpha 1/4
       K05700  VCL; vinculin
       K05701  TJP1, ZO1; tight junction protein 1
       K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
       K05690  CTNND1; catenin (cadherin-associated protein), delta 1
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K05693  PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
       K05694  PTPRB, PTPB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
       K05698  PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K05705  YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05706  SNAI2, SLUG; snail 2
       K05707  SNAI1; snail 1
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04468  NLK; nemo like kinase [EC:2.7.11.24]
     04530 Tight junction [PATH:ko04530]
     04540 Gap junction [PATH:ko04540]
     04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
 
   Cellular community - prokaryotes
 
   Cell motility
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K17453  PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
       K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
       K07190  PHKA_B; phosphorylase kinase alpha/beta subunit
       K02183  CALM; calmodulin
       K00688  PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
       K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07192  FLOT; flotillin
       K07193  APS, SH2B2; SH2B adapter protein 2
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K07194  RHOQ, TC10; Ras homolog gene family, member Q
       K07195  EXOC7, EXO70; exocyst complex component 7
       K07196  TRIP10, CIP4; thyroid hormone receptor interactor 10
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K11262  ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
       K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07201  FOXO1; forkhead box protein O1
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K02158  BAD; Bcl-2-antagonist of cell death
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
     04922 Glucagon signaling pathway [PATH:ko04922]
     04923 Regulation of lipolysis in adipocyte [PATH:ko04923]
       K05251  TSHB; thyroid stimulating hormone, beta
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K04249  TSHR; thyroid stimulating hormone receptor
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
       K19477  PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]
       K08768  PLIN1; perilipin-1
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K16816  PNPLA2, ATGL; patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]
       K13699  ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
       K01054  MGLL; acylglycerol lipase [EC:3.1.1.23]
       K08753  FABP4, aP2; fatty acid-binding protein 4, adipocyte
       K08771  AQP7; aquaporin-7
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04265  ADORA1; adenosine A1 receptor
       K04260  PTGER3; prostaglandin E receptor 3
       K05232  NPY; neuropeptide Y
       K04204  NPY1R; neuropeptide Y receptor type 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K08521  LHB; luteinizing hormone beta polypeptide
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K12473  LDLR; low-density lipoprotein receptor
       K13885  SCARB1; scavenger receptor class B, member 1
       K16931  STAR; steroidogenic acute regulatory protein, mitochondrial
       K00498  CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
       K00512  CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
       K00044  HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
       K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
       K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
       K00070  HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
       K05250  FSH; follicle stimulating hormone
       K04247  FSHR; follicle stimulating hormone receptor
       K07434  CYP19A; aromatase [EC:1.14.14.14]
       K07410  CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
       K07408  CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
       K05498  GDF9_9B; growth differentiation factor 9/9B
       K16620  BMP6; bone morphogenetic protein 6
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04926 Relaxin signaling pathway [PATH:ko04926]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04924 Renin secretion [PATH:ko04924]
     04614 Renin-angiotensin system [PATH:ko04614]
     04925 Aldosterone synthesis and secretion [PATH:ko04925]
     04927 Cortisol synthesis and secretion [PATH:ko04927]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
     04962 Vasopressin-regulated water reabsorption [PATH:ko04962]
     04960 Aldosterone-regulated sodium reabsorption [PATH:ko04960]
       K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
       K08555  NR3C2, MR; mineralocorticoid receptor
       K04824  SCNN1A; amiloride-sensitive sodium channel subunit alpha
       K04825  SCNN1B; amiloride-sensitive sodium channel subunit beta
       K04827  SCNN1G; amiloride-sensitive sodium channel subunit gamma
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K04995  KCNJ1; potassium inwardly-rectifying channel subfamily J member 1
       K13358  SLC9A3R2, NHERF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2
       K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]
       K06644  SFN; stratifin
       K07827  KRAS, KRAS2; GTPase KRas
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K13359  FXYD4, CHIF; FXYD domain containing ion transport regulator 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04961 Endocrine and other factor-regulated calcium reabsorption [PATH:ko04961]
     04964 Proximal tubule bicarbonate reclamation [PATH:ko04964]
     04966 Collecting duct acid secretion [PATH:ko04966]
 
   Nervous system
 
   Sensory system
 
   Development
 
   Aging
     04211 Longevity regulating pathway - mammal [PATH:ko04211]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K11420  EHMT; euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K08339  ATG5; autophagy-related protein 5
       K14756  KL; klotho [EC:3.2.1.31]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
       K08331  ATG13; autophagy-related protein 13
       K17589  RB1CC1; RB1-inducible coiled-coil protein 1
       K19730  ATG101; autophagy-related protein 101
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K02159  BAX; apoptosis regulator BAX
       K04451  TP53, P53; tumor protein p53
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K10141  SESN1_3; sestrin 1/3
       K20394  SESN2; sestrin 2
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
     04212 Longevity regulating pathway - worm [PATH:ko04212]
       K19763  JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K19764  INS7; insulin-like neuropeptide
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K09408  FOXO3; forkhead box protein O3
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K14966  HCFC; host cell factor
       K17491  SMEK, PPP4R3; protein phosphatase 4 regulatory subunit 3
       K14739  MT1_2; metallothionein 1/2
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K19765  HSBP1; heat shock factor-binding protein 1
       K18463  CCDC53; WASH complex subunit CCDC53
       K18461  WASH1; WAS protein family homolog 1
       K09414  HSF1; heat shock transcription factor 1
       K19766  HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
       K19767  HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
       K19768  HSP12.6; heat shock protein 12.6
       K19769  SIP1; stress-induced protein 1
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
       K11204  GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K08035  FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K19770  RNASEK; ribonuclease kappa [EC:3.1.-.-]
       K12824  TCERG1, CA150; transcription elongation regulator 1
       K17705  KRIT1; Krev interaction trapped protein 1
       K19771  LIPL4; lipase
       K19772  LIPS17; triacylglycerol lipase
       K14938  NVD, DAF36; cholesterol 7-desaturase [EC:1.14.19.21]
       K07418  CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
       K14035  NR1IN; nuclear receptor subfamily 1 group I
       K13356  FAR; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]
       K19773  NHR80; nuclear hormone receptor family member NHR-80
       K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K10798  PARP; poly [ADP-ribose] polymerase [EC:2.4.2.30]
       K01358  clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
       K19762  HAF1; ATP-binding cassette, subfamily B, HAIF transporter
       K19774  DVE1; homeobox domain-containing protein
       K13113  UBL5, HUB1; ubiquitin-like protein 5
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K17794  TIM23; mitochondrial import inner membrane translocase subunit TIM23
       K04043  dnaK, HSPA9; molecular chaperone DnaK
       K04077  groEL, HSPD1; chaperonin GroEL
     04213 Longevity regulating pathway - multiple species [PATH:ko04213]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K08339  ATG5; autophagy-related protein 5
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K19805  ILP7; insulin-like peptide 7
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K18644  EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
       K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
       K09542  CRYAB; crystallin, alpha B
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K19764  INS7; insulin-like neuropeptide
       K08035  FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
       K19766  HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
       K19767  HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
       K19768  HSP12.6; heat shock protein 12.6
       K19769  SIP1; stress-induced protein 1
       K12762  GPR1; G protein-coupled receptor GPR1
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
       K19798  GIS1; transcriptional activator/repressor GIS1
       K19800  SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
       K03695  clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
       K01440  PNC1; nicotinamidase [EC:3.5.1.19]
       K11121  SIR2; NAD-dependent histone deacetylase SIR2 [EC:3.5.1.-]
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
     04930 Type II diabetes mellitus [PATH:ko04930]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07296  ACDC; adiponectin
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K07594  IPF1, PDX1; insulin promoter factor 1
       K07595  MAFA; transcription factor MAFA
       K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K05004  KCNJ11; potassium inwardly-rectifying channel subfamily J member 11
       K05032  ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
     04940 Type I diabetes mellitus [PATH:ko04940]
     04950 Maturity onset diabetes of the young [PATH:ko04950]
     04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:ko04932]
       K05405  IL6; interleukin 6
       K05055  IL6R, CD126; interleukin 6 receptor
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K08536  NR1H3, LXRA; liver X receptor alpha
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K09113  MLX; MAX-like protein X
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K05424  LEP; leptin
       K05062  LEPR, CD295; leptin receptor
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K05632  ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04448  JUN; transcription factor AP-1
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K09027  XBP1; X box-binding protein 1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K07415  CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K10030  IL8, CXCL8; interleukin 8
       K13375  TGFB1; transforming growth factor beta-1
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K02159  BAX; apoptosis regulator BAX
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
     04931 Insulin resistance [PATH:ko04931]
       K04526  INS; insulin
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K05405  IL6; interleukin 6
       K04692  STAT3; signal transducer and activator of transcription 3
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K17902  TBC1D4, AS160; TBC1 domain family member 4
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K14497  PP2C; protein phosphatase 2C [EC:3.1.3.16]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
       K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
       K08745  SLC27A1_4, FATP1, FATP4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
       K08746  SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
       K08772  SLC27A3, FATP3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
       K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
       K08749  SLC27A6, FATP6; solute carrier family 27 (fatty acid transporter), member 6
       K06259  CD36; CD36 antigen
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K17605  PPP2R4, PTPA; serine/threonine-protein phosphatase 2A activator
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K07187  IRS2; insulin receptor substrate 2
       K19518  TRIB3; tribbles homolog 3
       K00688  PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
       K07201  FOXO1; forkhead box protein O1
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
       K08536  NR1H3, LXRA; liver X receptor alpha
       K08535  NR1H2, LXRB; liver X receptor beta
       K17962  PPARGC1B, PGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
       K09113  MLX; MAX-like protein X
       K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
       K11533  fas; fatty acid synthase, bacteria type [EC:2.3.1.-]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K15719  NCOAT, MGEA5; protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]
       K09667  OGT; protein O-GlcNAc transferase [EC:2.4.1.255]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K00820  glmS, GFPT; glucosamine---fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
     04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
 
   Infectious diseases
 
   Drug resistance

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: February 23, 2018