 Metabolism
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Genetic Information Processing
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 Environmental Information Processing
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Membrane transport
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Signal transduction
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02020 Two-component system [PATH:ko02020]
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 02022 Two-component system [BR:ko02022]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway -fly [PATH:ko04391]
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04370 VEGF signaling pathway [PATH:ko04370]
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04630 Jak-STAT signaling pathway [PATH:ko04630]
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K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K04687 IFNG; interferon gamma
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW1; interferon, omega 1
K05441 IFNK; interferon, kappa
K05442 IFNT1; interferon, tau-1
K05443 IL10, CSIF; interleukin 10
K05444 IL19_20_24; interleukin 19/20/24
K05445 IL22, IL-TIF; interleukin 22
K05446 IL26; interleukin 26
K05447 IL28_29, IFNL; interleukin 28/29 (interferon, lambda)
K04736 IL3; interleukin 3
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05428 IL5; interleukin 5
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05435 IL13; interleukin 13
K05436 TSLP; thymic stromal lymphopoietin
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05417 IL11; interleukin 11
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05421 BSF3, CLC; B-cell stimulating factor 3
K05422 CTF1, CT1; cardiotrophin 1
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23, alpha subunit p19
K04737 IL3RA; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB; cytokine receptor common subunit beta
K05055 IL6R; interleukin 6 receptor
K05056 IL11RA; interleukin 11 receptor alpha
K05057 OSMR; oncostatin M receptor
K05058 LIFR; leukemia inhibitory factor receptor
K05059 CNTFR; ciliary neurotrophic factor receptor
K05060 IL6ST, GP130; interleukin 6 signal transducer
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05062 LEPR; leptin receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K05066 CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
K05067 IL5RA; interleukin 5 receptor alpha
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05073 IL9R; interleukin 9 receptor
K05074 IL15RA; interleukin 15 receptor alpha
K05075 IL21R; interleukin 21 receptor
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05077 IL13RA2; interleukin 13 receptor alpha-2
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL; thrombopoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05134 IL10RA; interleukin 10 receptor alpha
K05135 IL10RB; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05139 IL22RA2; interleukin 22 receptor alpha 2
K05140 IL28RA; interleukin 28 receptor alpha
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS7, NAP4; suppressor of cytokine signaling 7
K04700 SOCSN; suppressor of cytokine signaling, invertebrate
K04701 CISH; cytokine inducible SH2-containing protein
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; cyclin D1
K10151 CCND2; cyclin D2
K10152 CCND3; cyclin D3
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K04703 SPRED; sprouty-related, EVH1 domain containing
K04704 SPRY; sprouty
K04705 STAM; signal transducing adaptor molecule
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:6.3.2.-]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05697 PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1; interleukin 1 receptor type I
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2
K09849 TRAF5; TNF receptor-associated factor 5
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
K10652 TRIM25, EFP; tripartite motif-containing protein 25
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; CD14 antigen
K10160 TLR4; toll-like receptor 4
K05400 LY96, MD-2; lymphocyte antigen 96
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03174 TRAF3; TNF receptor-associated factor 3
K05473 TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K05476 TNFSF13B, TNFSF20; tumor necrosis factor ligand superfamily member 13B
K05151 TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
K10577 UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
K04728 ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K10130 LRDD, PIDD; leucine-rich repeats and death domain-containing protein
K16072 ERC1; ELKS/RAB6-interacting/CAST family member 1
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator BCL-2
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic BCL2-related protein A1
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K10030 IL8, CXCL8; interleukin 8
K11859 TNFAIP3, A20; tumor necrosis factor, alpha-induced protein 3 [EC:3.-.-.-]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K12964 CCL4; C-C motif chemokine 4
K06527 VCAM1; vascular cell adhesion molecule 1
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K09253 RELB; transcription factor RelB
K16595 CCL13; C-C motif chemokine 13
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K10031 CXCL12; C-X-C motif chemokine 12
K06490 ICAM1; intercellular adhesion molecule 1
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; nerve growth factor receptor (TNFR superfamily member 16)
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; CD19 antigen
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 GBL; G protein beta subunit-like
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K06071 PKN; protein kinase N [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; thioesterase superfamily member 4
K04382 PPP2C; protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; protein phosphatase 2 (formerly 2A), regulatory subunit A
K04354 PPP2R2; protein phosphatase 2 (formerly 2A), regulatory subunit B
K11583 PPP2R3; protein phosphatase 2 (formerly 2A), regulatory subunit B''
K11584 PPP2R5; protein phosphatase 2 (formerly 2A), regulatory subunit B'
K04079 htpG, HSP90A; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; cyclin D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; cyclin D2
K10152 CCND3; cyclin D3
K06626 CCNE; cyclin E
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; BCL2-antagonist of cell death
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator BCL-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 NR2B1, RXRA; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB; myb proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K04451 TP53, P53; tumor protein p53
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
Signaling molecules and interaction
|
|
Cellular Processes
|
|
Transport and catabolism
|
|
Cell motility
|
|
Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
04210 Apoptosis [PATH:ko04210]
|
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K04721 TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04386 IL1R1; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K02373 FADD; FAS-associated death domain protein
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04726 BID; BH3 interacting domain death agonist
K02161 BCL2; apoptosis regulator BCL-2
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02310 DFFA, DFF45; DNA fragmentation factor, 45 kD, alpha subunit
K02311 DFFB, DFF40; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
K04727 PDCD8, AIF; programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-]
K01173 ENDOG; endonuclease G, mitochondrial
K04728 ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K03173 TRAF2; TNF receptor-associated factor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K04732 IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04736 IL3; interleukin 3
K04737 IL3RA; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB; cytokine receptor common subunit beta
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02158 BAD; BCL2-antagonist of cell death
K02159 BAX; apoptosis regulator BAX
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
|
04115 p53 signaling pathway [PATH:ko04115]
|
|
Cell communication
|
|
Organismal Systems
|
|
Human Diseases
|
|
Cancers
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL, DIP13A; DCC-interacting protein 13 alpha
K05689 CDHE, CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; cyclin D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K06237 COL4A; collagen, type IV, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator BCL-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K02158 BAD; BCL2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; proto-oncogene C-crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA_B; platelet derived growth factor A/B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04358 FGF; fibroblast growth factor
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 NR2B1, RXRA; retinoid X receptor alpha
K08525 NR2B2, RXRB; retinoid X receptor beta
K08526 NR2B3, RXRG; retinoid X receptor gamma
K08528 NR1B2, RARB; retinoic acid receptor beta
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K10054 PML, TRIM19; probable transcription factor PML
K08527 NR1B1, RARA; retinoic acid receptor alpha
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05405 IL6; interleukin 6
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K04453 MAX; Max protein
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; cyclin E
K06618 RB1; retinoblastoma-associated protein
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 EVI1; ecotropic virus integration site 1 protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 TCEB1; transcription elongation factor B, polypeptide 1
K03873 TCEB2; transcription elongation factor B, polypeptide 2
K03868 RBX1, ROC1; RING-box protein 1
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.-]
K01679 E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K06227 COS2; costal 2
K06228 FU; fused [EC:2.7.11.1]
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K04662 BMP2_4; bone morphogenetic protein 2/4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 NR3C4, AR; androgen receptor
K04079 htpG, HSP90A; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancers [PATH:ko05202]
|
K08367 RUNX1, AML1; runt-related transcription factor 1
K05090 CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04736 IL3; interleukin 3
K10053 RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11644 SIN3A; paired amphipathic helix protein Sin3a
K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K09438 SPI1; transcription factor PU.1
K04391 CD14; CD14 antigen
K06461 ITGAM; integrin alpha M
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K10056 JUP; junction plakoglobin
K10054 PML, TRIM19; probable transcription factor PML
K08527 NR1B1, RARA; retinoic acid receptor alpha
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K02162 BCL2A1; hematopoietic BCL2-related protein A1
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K04377 MYC; Myc proto-oncogene protein
K09063 TCF3, E2A; transcription factor E2-alpha
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K01558 WNT16; wingless-type MMTV integration site family, member 16
K03211 ETV6_7, yan; ETS translocation variant 6/7
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K01353 GZMB; granzyme B [EC:3.4.21.79]
K09186 MLL1; histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]
K15184 AFF1; AF4/FMR2 family member 1
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K15188 CCNT; cyclin T
K15187 MLLT1_3, ENL, AF9; YEATS domain-containing protein 1/3
K11427 DOT1L, DOT1; histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
K15612 LMO2; rhombotin-2
K15610 PBX3; pre-B-cell leukemia transcription factor 3
K09278 RUNX2, AML3; runt-related transcription factor 2
K04676 SMAD1; mothers against decapentaplegic homolog 1
K15605 KLF3; krueppel-like factor 3
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K11449 JMJD1C; jumonji domain-containing protein 1C [EC:1.14.11.-]
K09283 HMGA2; high mobility group AT-hook protein 2
K11447 UTX, UTY; histone demethylase [EC:1.14.11.-]
K11313 SUPT3H, SPT3; transcription initiation protein SPT3
K06532 PROM1; prominin 1
K05092 FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K08854 BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K08821 CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15613 MEIS1; homeobox protein Meis1
K15614 SIX1; homeobox protein SIX1
K15615 SIX4; homeobox protein SIX4
K15616 EYA1; eyes absent homolog 1 [EC:3.1.3.48]
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K00069 HPGD; 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141]
K05199 GRIA3; glutamate receptor 3
K00717 FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
K15607 TLX3, HOX11L2; T-cell leukemia homeobox protein 3
K09340 TLX1, HOX11; T-cell leukemia homeobox protein 1
K04182 CCR7; C-C chemokine receptor type 7
K15617 LDB1; LIM domain-binding protein 1
K15604 LYL1; protein lyl-1
K08024 HHEX, HEX, PRH; homeobox protein HEX
K06056 PTCRA; pre T-cell antigen receptor alpha
K09254 REL; c-Rel proto-oncogene protein
K03172 TRAF1; TNF receptor-associated factor 1
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K05413 CD86; CD86 antigen
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K15618 BCL6; B-cell lymphoma 6 protein
K06856 IGH; immunoglobulin heavy chain
K09035 CMAF, MAF; transcription factor Maf
K10151 CCND2; cyclin D2
K06590 ITGB7; integrin beta 7
K11424 WHSC1, MMSET, NSD2; histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]
K11253 H3; histone H3
K09383 PAX5; paired box protein 5
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 NR2B1, RXRA; retinoid X receptor alpha
K08525 NR2B2, RXRB; retinoid X receptor beta
K08526 NR2B3, RXRG; retinoid X receptor gamma
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K09633 TMPRSS2; transmembrane protease, serine 2
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K15619 SPINT1; Kunitz-type protease inhibitor 1
K04387 IL1R2; interleukin 1 receptor type II
K09431 ETV1; ets translocation variant 1
K15592 ETV4; ets translocation variant 4
K15593 ETV5; ets translocation variant 5
K15379 SLC45A3; solute carrier family 45, member 3
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
K09109 NMYC, MYCN; N-myc proto-oncogene protein
K04453 MAX; Max protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04451 TP53, P53; tumor protein p53
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K04684 SP1; transcription factor Sp1
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K02583 NGFR; nerve growth factor receptor (TNFR superfamily member 16)
K14970 MEN1, MNN1; menin
K13209 EWSR1; RNA-binding protein EWS
K09436 FLI1; friend leukemia integration 1 transcription factor
K05459 IGF1; insulin-like growth factor 1
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K09437 FEV; ETS oncogene family protein FEV
K09053 ATF1; activating transcription factor 1
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04728 ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K15620 GOLPH3, GPP34; golgi phosphoprotein 3
K09234 WT1; Wilms tumor protein 1
K04359 PDGFA_B; platelet derived growth factor A/B
K05069 IL2RB; interleukin 2 receptor beta
K15621 BAIAP3; BAI1-associated protein 3
K06571 TM4SF2, MXS1; transmembrane 4 superfamily member 2
K15622 MLF1; myeloid leukemia factor 1
K08559 NR4A3, NOR1; nuclear receptor subfamily 4 group A member 3
K14651 TAF15; transcription initiation factor TFIID subunit 15
K13098 TLS, FUS; RNA-binding protein FUS
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K05405 IL6; interleukin 6
K14242 NFKBIZ; NF-kappa-B inhibitor zeta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8, CXCL8; interleukin 8
K07201 FOXO1; forkhead box protein O1
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K15623 SS18, SSXT, SYT; protein SSXT
K15624 SSX1; protein SSX1
K15625 SSX2; protein SSX2
K15626 NUPR1, COM1; nuclear protein, 1
K15627 ASPSCR1, ASPL; tether containing UBX domain for GLUT4
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis [PATH:ko05204]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
K07827 KRAS, KRAS2; GTPase KRas
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; BCL2-antagonist of cell death
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; cyclin D1
K06618 RB1; retinoblastoma-associated protein
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K04451 TP53, P53; tumor protein p53
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; proto-oncogene C-crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; BCL2-antagonist of cell death
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K04364 GRB2; growth factor receptor-binding protein 2
K08091 GAB2; growth factor receptor bound protein 2-associated protein 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K06279 SHC; src homology 2 domain-containing transforming protein C
K04377 MYC; Myc proto-oncogene protein
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; cyclin D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 EVI1; ecotropic virus integration site 1 protein
K08367 RUNX1, AML1; runt-related transcription factor 1
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
05213 Endometrial cancer [PATH:ko05213]
|
05222 Small cell lung cancer [PATH:ko05222]
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 NR1B2, RARB; retinoic acid receptor beta
K08524 NR2B1, RXRA; retinoid X receptor alpha
K08525 NR2B2, RXRB; retinoid X receptor beta
K08526 NR2B3, RXRG; retinoid X receptor gamma
K04451 TP53, P53; tumor protein p53
K02161 BCL2; apoptosis regulator BCL-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04377 MYC; Myc proto-oncogene protein
K04453 MAX; Max protein
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; cyclin D1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; cyclin E
K06618 RB1; retinoblastoma-associated protein
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K06237 COL4A; collagen, type IV, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
Immune diseases
|
|
Neurodegenerative diseases
|
05010 Alzheimer's disease [PATH:ko05010]
|
05012 Parkinson's disease [PATH:ko05012]
|
05014 Amyotrophic lateral sclerosis (ALS) [PATH:ko05014]
|
K04451 TP53, P53; tumor protein p53
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04726 BID; BH3 interacting domain death agonist
K02161 BCL2; apoptosis regulator BCL-2
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K02158 BAD; BCL2-antagonist of cell death
K02084 APAF1; apoptotic protease-activating factor
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K11518 TOM40; mitochondrial import receptor subunit TOM40
K11519 DERL1; Derlin-1
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
K02308 DAXX; death-associated protein 6
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04569 CCS; copper chaperone for superoxide dismutase
K03781 katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
K07607 PRPH; peripherin
K04572 NEFL, NF-L; neurofilament light polypeptide
K04573 NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
K04574 NEFH, NF-H; neurofilament heavy polypeptide
K04575 ALS2; amyotrophic lateral sclerosis 2 protein
K07887 RAB5A; Ras-related protein Rab-5A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05613 SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
|
05016 Huntington's disease [PATH:ko05016]
|
05020 Prion diseases [PATH:ko05020]
|
|
Substance dependence
|
|
Cardiovascular diseases
|
|
Endocrine and metabolic diseases
|
|
Infectious diseases
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
05166 HTLV-I infection [PATH:ko05166]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1; neuropilin 1
K06527 VCAM1; vascular cell adhesion molecule 1
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06490 ICAM1; intercellular adhesion molecule 1
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06271 TLN; talin
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; cyclin D2
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K06751 MHC1; major histocompatibility complex, class I
K08057 CALR; calreticulin
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K04446 NFATC, NFAT; nuclear factor of activated T-cells, cytoplasmic
K08054 CANX; calnexin
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 BZRP; benzodiazapine receptor
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03356 APC9; anaphase-promoting complex subunit 9
K03357 APC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12416 SWM1, APC13; anaphase-promoting complex subunit SWM1
K06635 PTTG; securin
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04802 PCNA; proliferating cell nuclear antigen
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04503 CCND1; cyclin D1
K10152 CCND3; cyclin D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K04690 FZDN, fz3; frizzled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K12076 DLG1; disks large protein 1
K04359 PDGFA_B; platelet derived growth factor A/B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K15307 GPS2; G protein pathway suppressor 2
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K15308 TTP; tristetraprolin
K08065 NFYB; nuclear transcription Y subunit beta
K06752 MHC2; major histocompatibility complex, class II
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS, pnt; c-ets proto-oncogene protein
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K12496 EGR2; early growth response protein 2
K04502 FOSL1; fos-like antigen 1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09052 CREM; cAMP response element modulator
K09053 ATF1; activating transcription factor 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09032 ATF3, LRF1; activating transcription factor 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09027 XBP1; X box-binding protein 1
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09420 MYB; myb proto-oncogene protein
K09421 MYBL; myb-related protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04728 ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
K06641 CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K15310 TP53INP1; tumor protein p53-inducible nuclear protein 1
K09341 MSX; homeobox protein MSX
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05162 Measles [PATH:ko05162]
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05164 Influenza A [PATH:ko05164]
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05161 Hepatitis B [PATH:ko05161]
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05160 Hepatitis C [PATH:ko05160]
|
05168 Herpes simplex infection [PATH:ko05168]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05146 Amoebiasis [PATH:ko05146]
|
05144 Malaria [PATH:ko05144]
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05145 Toxoplasmosis [PATH:ko05145]
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K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; class II, major histocompatibility complex, transactivator
K06752 MHC2; major histocompatibility complex, class II
K14139 IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
K14140 IGTP; interferon gamma induced GTPase
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K14141 PFNL; profilin-like protein
K14142 TLR11; toll-like receptor 11
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNFA; tumor necrosis factor superfamily, member 2
K02161 BCL2; apoptosis regulator BCL-2
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4; toll-like receptor 4
K03283 HSPA1_8; heat shock 70kDa protein 1/8
K10159 TLR2; toll-like receptor 2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06485 ITGA6; integrin alpha 6
K05719 ITGB1; integrin beta 1
K14143 SAG; major surface antigen
K14144 MIC3; microneme protein
K13412 CPK; calcium-dependent protein kinase [EC:2.7.11.1]
K13845 AMA-1; apical merozoite antigen 1
K14145 RON2; rhoptry neck protein 2
K14146 RON4; rhoptry neck protein 4
K12473 LDLR; low-density lipoprotein receptor
K14147 GRA7; dense granule protein 7
K14148 ROP2; rhoptry protein 2
K14149 GRA3; dense granule protein 3
K14150 GRA5; dense granule protein 5
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; BCL2-antagonist of cell death
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04180 CCR5; C-C chemokine receptor type 5
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K14151 ROP16; rhoptry protein 16
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA; interleukin 10 receptor alpha
K05135 IL10RB; interleukin 10 receptor beta
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
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05140 Leishmaniasis [PATH:ko05140]
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05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
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05143 African trypanosomiasis [PATH:ko05143]
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KEGG Orthology (KO)