 09100 Metabolism
|
|
 09120 Genetic Information Processing
|
|
09121 Transcription
|
|
09122 Translation
|
|
09123 Folding, sorting and degradation
|
03060 Protein export [PATH:ko03060]
|
04141 Protein processing in endoplasmic reticulum [PATH:ko04141]
|
04130 SNARE interactions in vesicular transport [PATH:ko04130]
|
04120 Ubiquitin mediated proteolysis [PATH:ko04120]
|
04122 Sulfur relay system [PATH:ko04122]
|
03050 Proteasome [PATH:ko03050]
|
 K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K06691 RPN13; 26S proteasome regulatory subunit N13
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K06696 PSME1; proteasome activator subunit 1 (PA28 alpha)
K06697 PSME2; proteasome activator subunit 2 (PA28 beta)
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K06699 PSME4; proteasome activator subunit 4
K13527 mpa; proteasome-associated ATPase
K03420 psmR; proteasome regulatory subunit
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K02741 PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]
K02733 PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]
K02740 PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]
K11598 PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]
K03432 psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
K03433 psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
K04687 IFNG; interferon gamma
K06700 PSMF1; proteasome inhibitor subunit 1 (PI31)
K11599 POMP, UMP1; proteasome maturation protein
|
03018 RNA degradation [PATH:ko03018]
|
|
09124 Replication and repair
|
|
09126 Chromosome
|
|
09125 Information processing in viruses
|
|
09130 Environmental Information Processing
|
|
09131 Membrane transport
|
|
09132 Signal transduction
|
02020 Two-component system [PATH:ko02020]
|
04010 MAPK signaling pathway [PATH:ko04010]
|
04013 MAPK signaling pathway - fly [PATH:ko04013]
|
04016 MAPK signaling pathway - plant [PATH:ko04016]
|
04011 MAPK signaling pathway - yeast [PATH:ko04011]
|
04012 ErbB signaling pathway [PATH:ko04012]
|
04014 Ras signaling pathway [PATH:ko04014]
|
04015 Rap1 signaling pathway [PATH:ko04015]
|
04310 Wnt signaling pathway [PATH:ko04310]
|
04330 Notch signaling pathway [PATH:ko04330]
|
04340 Hedgehog signaling pathway [PATH:ko04340]
|
04341 Hedgehog signaling pathway - fly [PATH:ko04341]
|
04350 TGF-beta signaling pathway [PATH:ko04350]
|
K04657 CHRD; chordin
K04658 NOG; noggin
K19558 NBL1; neuroblastoma suppressor of tumorigenicity 1
K23318 GREM; gremlin
K16857 THBS1; thrombospondin 1
K04660 DCN; decorin
K08121 FMOD; fibromodulin
K04668 LEFTY; left-right determination factor
K04661 FST; follistatin
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16620 BMP6; bone morphogenetic protein 6
K22687 INHBB; inhibin beta B chain
K14736 TF; transferrin
K04663 BMP5; bone morphogenetic protein 5
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K23377 THSD4, ADAMTSL6; thrombospondin type-1 domain-containing protein 4
K06825 FBN1; fibrillin 1
K19559 LTBP1; latent transforming growth factor beta binding protein 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04667 INHBA; inhibin beta A chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04666 NODAL; nodal
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K23100 HJV, RGMC; hemojuvelin
K06766 NEO1; neogenin
K26535 HFE; hereditary hemochromatosis protein
K23910 TFR2; transferrin receptor protein 2
K06503 TFRC, CD71; transferrin receptor
K23096 RGMA; repulsive guidance molecule A
K06847 RGMB; RGM domain family member B
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K26257 EMP3; epithelial membrane protein 3
K26316 LRRC32; transforming growth factor beta activator LRRC32
K26317 NRROS, LRRC33; transforming growth factor beta activator LRRC33
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K26168 IGSF1; immunoglobulin superfamily member 1
K10162 BAMBI; BMP and activin membrane-bound inhibitor
K04676 SMAD1; mothers against decapentaplegic homolog 1
K16790 SMAD5; mothers against decapentaplegic homolog 5
K16791 SMAD9, SMAD8; mothers against decapentaplegic homolog 9
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04677 SMAD6; mothers against decapentaplegic homolog 6
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K04679 MADHIP, SARA; MAD, mothers against decapentaplegic interacting protein
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K23106 HAMP; hepcidin
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K17694 ID3; DNA-binding protein inhibitor ID3
K17695 ID4; DNA-binding protein inhibitor ID4
K17696 EMC; DNA-binding protein inhibitor ID, other
K04681 RBL1; retinoblastoma-like protein 1
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K18499 SKIL; Ski-like protein
K26503 SKI; Ski oncogene
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
K19383 TGIF1; homeobox protein TGIF1
K19553 TGIF2; homeobox protein TGIF2
K04377 MYC; Myc proto-oncogene protein
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K04686 PITX2; paired-like homeodomain transcription factor 2
|
04390 Hippo signaling pathway [PATH:ko04390]
|
04391 Hippo signaling pathway - fly [PATH:ko04391]
|
04392 Hippo signaling pathway - multiple species [PATH:ko04392]
|
04370 VEGF signaling pathway [PATH:ko04370]
|
04371 Apelin signaling pathway [PATH:ko04371]
|
04630 JAK-STAT signaling pathway [PATH:ko04630]
|
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05435 IL13; interleukin 13
K22629 IL27, IL27A; interleukin 27 subunit alpha
K22631 IL31; interleukin 31
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05057 OSMR; oncostatin M receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05059 CNTFR; ciliary neurotrophic factor receptor
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K05445 IL22, IL-TIF; interleukin 22
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05139 IL22RA2; interleukin 22 receptor alpha 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K16689 UPD; unpaired
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K19599 DOME; cytokine receptor domeless
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K02161 BCL2; apoptosis regulator Bcl-2
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K05640 GFAP; glial fibrillary acidic protein
K04705 STAM; signal transducing adaptor molecule
K18026 PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K14365 FHL1, SLIM1; four and a half LIM domains protein 1
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
|
04064 NF-kappa B signaling pathway [PATH:ko04064]
|
04668 TNF signaling pathway [PATH:ko04668]
|
04066 HIF-1 signaling pathway [PATH:ko04066]
|
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K04692 STAT3; signal transducer and activator of transcription 3
K10160 TLR4, CD284; toll-like receptor 4
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K16451 TIMP1; metalloproteinase inhibitor 1
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05437 EPO; erythropoietin
K14736 TF; transferrin
K06503 TFRC, CD71; transferrin receptor
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K16366 EDN1; endothelin-1
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K12334 NPPA; natriuretic peptide A
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00844 HK; hexokinase [EC:2.7.1.1]
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00134 GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01689 ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11]
K00927 PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K00016 LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]
K02161 BCL2; apoptosis regulator Bcl-2
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K00161 PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
K00162 PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
|
04068 FoxO signaling pathway [PATH:ko04068]
|
04020 Calcium signaling pathway [PATH:ko04020]
|
04070 Phosphatidylinositol signaling system [PATH:ko04070]
|
04072 Phospholipase D signaling pathway [PATH:ko04072]
|
04071 Sphingolipid signaling pathway [PATH:ko04071]
|
04024 cAMP signaling pathway [PATH:ko04024]
|
04022 cGMP-PKG signaling pathway [PATH:ko04022]
|
04151 PI3K-Akt signaling pathway [PATH:ko04151]
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
|
04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
|
K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K12499 CCL5; C-C motif chemokine 5
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K14624 CCL2, MCP1; C-C motif chemokine 2
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K21094 CCL18; C-C motif chemokine 18
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10035 CXCL16; C-X-C motif chemokine 16
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K22627 CXCL17; C-X-C motif chemokine 17
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05435 IL13; interleukin 13
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05419 LIF; leukemia inhibitory factor
K05418 OSM; oncostatin M
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05445 IL22, IL-TIF; interleukin 22
K05446 IL26; interleukin 26
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05447 IFNL1, IL29; interferon lambda 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05441 IFNK; interferon kappa
K05442 IFNE; interferon epsilon
K04687 IFNG; interferon gamma
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05485 IL37, IL1F7; interleukin 37
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K22628 IL16; interleukin 16
K22632 IL32; interleukin 32
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05480 EDA; ectodysplasin-A
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05504 GDF15; growth differentiation factor 15
K05503 GDF2, BMP9; growth differentiation factor 2
K22670 BMP10; bone morphogenetic protein 10
K05500 INHA; inhibin, alpha
K05496 BMP3; bone morphogenetic protein 3
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05497 MSTN, GDF8; growth differentiation factor 8
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K05495 GDF1; growth differentiation factor 1
K22672 GDF3; growth differentiation factor 3
K04666 NODAL; nodal
K22673 GDF9; growth differentiation factor 9
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04185 CCR10; C-C chemokine receptor type 10
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05059 CNTFR; ciliary neurotrophic factor receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05057 OSMR; oncostatin M receptor
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05172 IL1RL2, IL1RRP2; interleukin 1 receptor-like 2
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05171 IL1RL1, ST2; interleukin 1 receptor-like 1
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K05168 IL17RE; interleukin 17 receptor E
K06454 CD4; T-cell surface glycoprotein CD4
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K05143 TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05160 TNFRSF25; tumor necrosis factor receptor superfamily member 25
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05157 TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K05163 EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05149 TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
K05144 TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
K05145 TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05146 TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
K05142 TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
K05154 TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K05155 TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
K05156 RELT, TNFRSF19L; tumor necrosis factor receptor superfamily member 19-like
K26541 RELL; RELT-like protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
|
04061 Viral protein interaction with cytokine and cytokine receptor [PATH:ko04061]
|
04512 ECM-receptor interaction [PATH:ko04512]
|
04514 Cell adhesion molecules [PATH:ko04514]
|
|
09140 Cellular Processes
|
|
09141 Transport and catabolism
|
|
09143 Cell growth and death
|
04110 Cell cycle [PATH:ko04110]
|
04111 Cell cycle - yeast [PATH:ko04111]
|
04112 Cell cycle - Caulobacter [PATH:ko04112]
|
04113 Meiosis - yeast [PATH:ko04113]
|
04114 Oocyte meiosis [PATH:ko04114]
|
04210 Apoptosis [PATH:ko04210]
|
04214 Apoptosis - fly [PATH:ko04214]
|
04215 Apoptosis - multiple species [PATH:ko04215]
|
04216 Ferroptosis [PATH:ko04216]
|
04217 Necroptosis [PATH:ko04217]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K17595 SPATA2; spermatogenesis-associated protein 2
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K00261 GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K01915 glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
K00688 PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K00522 FTH1; ferritin heavy chain [EC:1.16.3.1]
K13625 FTL; ferritin light chain
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00460 ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K12350 SMPD1, ASM; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04519 IL1B; interleukin 1 beta
K12191 CHMP2A; charged multivesicular body protein 2A
K12192 CHMP2B; charged multivesicular body protein 2B
K12193 VPS24, CHMP3; charged multivesicular body protein 3
K12194 CHMP4A_B, SNF7, VPS32A_B; charged multivesicular body protein 4A/B
K24782 CHMP4C, SNF7, VPS32C; charged multivesicular body protein 4C
K12195 CHMP6, VPS20; charged multivesicular body protein 6
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12197 CHMP1, VPS46, DID2; charged multivesicular body protein 1
K12198 CHMP5, VPS60; charged multivesicular body protein 5
K15053 CHMP7; charged multivesicular body protein 7
K04982 TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04383 IL1A; interleukin 1 alpha
K12967 IL33; interleukin 33
K10802 HMGB1; high mobility group protein B1
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K10160 TLR4, CD284; toll-like receptor 4
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K05401 TLR3, CD283; toll-like receptor 3
K12965 ZBP1, DAI; Z-DNA binding protein 1
K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
K14381 SQSTM1; sequestosome 1
K04079 HSP90A, htpG; molecular chaperone HtpG
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04727 AIFM1, PDCD8; apoptosis-inducing factor 1 [EC:1.-.-.-]
K11251 H2A; histone H2A
K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
K02161 BCL2; apoptosis regulator Bcl-2
|
04115 p53 signaling pathway [PATH:ko04115]
|
04218 Cellular senescence [PATH:ko04218]
|
|
09144 Cellular community - eukaryotes
|
|
09145 Cellular community - prokaryotes
|
|
09142 Cell motility
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
K06751 MHC1; MHC class I antigen
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06523 ICAM2, CD102; intercellular adhesion molecule 2
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
K24233 KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
K06742 NCR2, CD336; natural cytotoxicity triggering receptor 2
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K19251 HA; Influenza A virus hemagglutinin
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K06741 NCR1, CD335; natural cytotoxicity triggering receptor 1
K06743 NCR3, CD337; natural cytotoxicity triggering receptor 3
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K26356 LAT2, LAB; linker for activation of T-cells family member 2
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K06728 KLRK1, CD314; killer cell lectin-like receptor subfamily K member 1
K07988 HCST, DAP10; hematopoietic cell signal transducer
K06479 CD48, BCM1; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K07989 SH2D1B, EAT2; SH2 domain-containing protein 1B
K07990 SH2D1A, SAP; SH2 domain-containing protein 1A
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K24207 KLRA1, Ly49A; killer cell lectin-like receptor subfamily A member 1
K24208 KLRA3, Ly49C; killer cell lectin-like receptor subfamily A member 3
K24238 KLRA7, Ly49G2; killer cell lectin-like receptor subfamily A member 7
K24240 KLRA9, Ly49I; killer cell lectin-like receptor subfamily A member 9
K23459 KLRA4, LY49D; killer cell lectin-like receptor subfamily A member 4
K24239 KLRA8, Ly49H; killer cell lectin-like receptor subfamily A member 8
K07987 RAET1; retinoic acid early transcript 1
|
04612 Antigen processing and presentation [PATH:ko04612]
|
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K06696 PSME1; proteasome activator subunit 1 (PA28 alpha)
K06697 PSME2; proteasome activator subunit 2 (PA28 beta)
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K26598 HSPA2; heat shock 70kDa protein 2
K09489 HSPA4; heat shock 70kDa protein 4
K04079 HSP90A, htpG; molecular chaperone HtpG
K06751 MHC1; MHC class I antigen
K09490 HSPA5, BIP; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K08054 CANX; calnexin
K08055 B2M; beta-2-microglobulin
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K08058 TAPBP; TAP binding protein (tapasin)
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24231 KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K24233 KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
K24234 KLRC4, NKG2F; killer cell lectin-like receptor subfamily C4
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
K07982 KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
K08059 IFI30, GILT; interferon, gamma-inducible protein 30
K01369 LGMN; legumain [EC:3.4.22.34]
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K06454 CD4; T-cell surface glycoprotein CD4
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08061 RFX5; regulatory factor X 5
K08062 RFXANK; regulatory factor X-associated ankyrin-containing protein
K08063 RFXAP; regulatory factor X-associated protein
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K08064 NFYA, HAP2; nuclear transcription factor Y, alpha
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K08066 NFYC, HAP5; nuclear transcription factor Y, gamma
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K07366 GRAP2, GADS; GRB2-related adaptor protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12076 DLG1; disks large protein 1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K03099 SOS; son of sevenless
K04350 RASGRP1; RAS guanyl-releasing protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K06470 CD28; CD28 antigen
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K04687 IFNG; interferon gamma
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
K06051 DLL; delta
K20995 NOTCH3; Notch 3
K06061 MAML; mastermind
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11222 STAT4; signal transducer and activator of transcription 4
K10166 TBX21; T-box protein 21
K09279 RUNX3, AML2; runt-related transcription factor 3
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K09035 CMAF, MAF; transcription factor Maf
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
|
04659 Th17 cell differentiation [PATH:ko04659]
|
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09445 IRF4; interferon regulatory factor 4
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K05434 IL21; interleukin 21
K05075 IL21R, CD360; interleukin 21 receptor
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04079 HSP90A, htpG; molecular chaperone HtpG
K09093 AHR; aryl hydrocarbon receptor
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05445 IL22, IL-TIF; interleukin 22
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K08367 RUNX1, AML1; runt-related transcription factor 1
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K19598 IL27RA; interleukin 27 receptor alpha
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K10163 FOXP3, IPEX; forkhead box P3
K08527 RARA, NR1B1; retinoic acid receptor alpha
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
K05493 IL17E, IL25; interleukin 17E
K05164 IL17RA, CD217; interleukin 17 receptor A
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04502 FOSL1; fos-like antigen 1
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K21083 CCL17; C-C motif chemokine 17
K16597 CCL11; C-C motif chemokine 11
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K03174 TRAF3; TNF receptor-associated factor 3
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K09848 TRAF4; TNF receptor-associated factor 4
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K13088 ELAVL1, HUR; ELAV-like protein 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K14624 CCL2, MCP1; C-C motif chemokine 2
K05509 CCL7; C-C motif chemokine 7
K14625 CCL20; C-C motif chemokine 20
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21100 DEFB4; beta-defensin 4
K13908 MUC5; mucin-5
K21126 S100A7; protein S100-A7
K21127 S100A8; protein S100-A8
K21128 S100A9; protein S100-A9
K21129 LCN2; lipocalin 2
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K05491 IL17C, CX2; interleukin 17C
K05168 IL17RE; interleukin 17 receptor E
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K05490 IL17B, CX1; interleukin 17B
K05492 IL17D, IL27; interleukin 17D
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
04320 Dorso-ventral axis formation [PATH:ko04320]
|
04360 Axon guidance [PATH:ko04360]
|
04361 Axon regeneration [PATH:ko04361]
|
04380 Osteoclast differentiation [PATH:ko04380]
|
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K05415 IFNB; interferon beta
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K09030 FOSL2; fos-like antigen 2
K04502 FOSL1; fos-like antigen 1
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K09028 JUNB; transcription factor jun-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K08008 NOX1, MOX1; NADPH oxidase 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K14377 OSCAR; osteoclast-associated immunoglobulin-like receptor
K06512 LILR, CD85; leukocyte immunoglobulin-like receptor
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K14378 TREM2; triggering receptor expressed on myeloid cells 2
K06551 SIRPA_B1_G, CD172; signal-regulatory protein alpha/beta1/gamma
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K07361 LCP2; lymphocyte cytosolic protein 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05853 ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
K26770 TMEM64; transmembrane protein 64
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09438 SPI1; transcription factor PU.1
K09455 MITF; microphthalmia-associated transcription factor
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K04576 CALCR; calcitonin receptor
K06493 ITGB3, CD61; integrin beta 3
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K08091 GAB2; GRB2-associated-binding protein 2
K14380 FHL2; four and a half LIM domains protein 2
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K14381 SQSTM1; sequestosome 1
|
|
09149 Aging
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP, PG; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3, PSA; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K04692 STAT3; signal transducer and activator of transcription 3
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10161 TLR9, CD289; toll-like receptor 9
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05842 TRIF; toll-like receptor adapter molecule 1
K05409 TIRP, TRAM; TRIF-related adaptor molecule
K06745 PDL1, CD274; programmed cell death 1 ligand 1
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K09034 BATF; ATF-like basic leucine zipper transcriptional factor
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04350 RASGRP1; RAS guanyl-releasing protein 1
K06470 CD28; CD28 antigen
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
|
|
09162 Cancer: specific types
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
K12473 LDLR; low-density lipoprotein receptor
K22272 E2; Hepatitis C virus envelope glycoprotein E2
K13885 SCARB1; scavenger receptor class B, member 1
K06508 CD81, TAPA1, TSPAN28; CD81 antigen
K06087 CLDN; claudin
K06088 OCLN; occludin
K24861 E1; Hepatitis C virus envelope glycoprotein E1
K22497 NS2; Hepatitis C virus non-structural protein 2 [EC:3.4.22.-]
K22273 NS3; Hepatitis C virus serine protease / helicase NS3 [EC:3.4.21.98 3.6.1.15 3.6.4.13]
K22274 NS4A; Hepatitis C virus non-structural protein 4A
K22498 NS4B; Hepatitis C virus non-structural protein 4B
K22275 NS5A; Hepatitis C virus non-structural protein 5A
K22472 NS5B; Hepatitis C virus RNA-dependent RNA polymerase [EC:2.7.7.48]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K22271 Core; Hepatitis C virus core protein
K14217 IFIT1; interferon-induced protein with tetratricopeptide repeats 1
K03250 EIF3E, INT6; translation initiation factor 3 subunit E
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04692 STAT3; signal transducer and activator of transcription 3
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02158 BAD; Bcl-2-antagonist of cell death
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04451 TP53, P53; tumor protein p53
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K08524 RXRA, NR2B1; retinoid X receptor alpha
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K08536 NR1H3, LXRA; liver X receptor alpha
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05171 Coronavirus disease - COVID-19 [PATH:ko05171]
|
05164 Influenza A [PATH:ko05164]
|
K19251 HA; Influenza A virus hemagglutinin
K19392 NA; Influenza A/B virus neuraminidase [EC:3.2.1.18]
K19394 M2; Influenza A virus matrix protein 2
K19393 M1; Influenza A/B virus matrix protein 1
K19391 NP; Influenza virus nucleoprotein
K19390 PA; Influenza virus polymerase acidic protein
K19389 PB1; Influenza virus RNA-directed RNA polymerase catalytic subunit [EC:2.7.7.48]
K19388 PB2; Influenza virus polymerase basic protein 2
K19396 NS1; Influenza A virus non-structural protein 1
K19397 PB1F2; Influenza A virus protein PB1-F2
K19395 NEP, NS2; Influenza A virus nuclear export protein
K01340 E3.4.21.59; tryptase [EC:3.4.21.59]
K01315 PLG; plasminogen [EC:3.4.21.7]
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4]
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-]
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K09507 DNAJB1; DnaJ homolog subfamily B member 1
K09523 DNAJC3; DnaJ homolog subfamily C member 3
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10652 TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12653 NLRX1; NLR family member X1
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K10160 TLR4, CD284; toll-like receptor 4
K05404 TLR7; toll-like receptor 7
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K10030 IL8, CXCL8; interleukin 8
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14754 MX; interferon-induced GTP-binding protein Mx
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K14404 CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
K14396 PABPN1, PABP2; polyadenylate-binding protein 2
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K15047 HNRNPUL1, E1BAP5; heterogeneous nuclear ribonucleoprotein U-like protein 1
K14298 RAE1, GLE2; mRNA export factor
K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
K15045 RSAD2; radical S-adenosyl methionine domain-containing protein 2
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05692 ACTB_G1; actin beta/gamma 1
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K14290 XPO1, CRM1; exportin-1
K23940 KPNA1; importin subunit alpha-5
K15043 KPNA2_7; importin subunit alpha-1/8
K15042 KPNA5_6; importin subunit alpha-6/7
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K14624 CCL2, MCP1; C-C motif chemokine 2
K19264 gD; Simplexvirus envelope glycoprotein D
K06081 NECTIN1, PVRL1, CD111; poliovirus receptor-related protein 1
K06531 PVRL2, CD112; poliovirus receptor-related protein 2
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K15411 PILR; paired immunoglobulin-like type 2 receptor
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K19434 gH, UL22; Simplexvirus envelope glycoprotein H
K19435 gL, UL1; Simplexvirus envelope glycoprotein L
K06484 ITGA5, CD49e; integrin alpha 5
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K12794 CARD9; caspase recruitment domain-containing protein 9
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K19436 ICP0, RL2; Simplexvirus E3 ubiquitin-protein ligase ICP0
K04451 TP53, P53; tumor protein p53
K03990 C3; complement component 3
K03994 C5; complement component 5
K15412 CFP; complement factor properdin
K10159 TLR2, CD282; toll-like receptor 2
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K09447 IRF7; interferon regulatory factor 7
K05401 TLR3, CD283; toll-like receptor 3
K19439 US3; Simplexvirus serine/threonine-protein kinase US3 [EC:2.7.11.1]
K05842 TRIF; toll-like receptor adapter molecule 1
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04519 IL1B; interleukin 1 beta
K12499 CCL5; C-C motif chemokine 5
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K19438 US11; Simplexvirus RNA-binding protein
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K21075 UL36, UL48; Herpesviridae large tegument protein deneddylase [EC:3.4.19.12 3.4.22.-]
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K19437 RL1; Simplexvirus neurovirulence factor ICP34.5
K05414 IFNA; interferon alpha
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K19447 UL41; Simplexvirus virion host shutoff protein [EC:3.1.27.-]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K03239 EIF2B1; translation initiation factor eIF-2B subunit alpha
K03754 EIF2B2; translation initiation factor eIF-2B subunit beta
K03241 EIF2B3; translation initiation factor eIF-2B subunit gamma
K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
K03240 EIF2B5; translation initiation factor eIF-2B subunit epsilon
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K19444 UL48; Simplexvirus tegument protein VP16
K14966 HCFC1; host cell factor 1
K27390 HCFC2; host cell factor 2
K09364 POU2F, OTF; POU domain transcription factor, class 2
K19445 ICP4, RS1; Simplexvirus major viral transcription factor ICP4
K19441 US1; Simplexvirus transcriptional regulator ICP22
K19443 UL54; Simplexvirus mRNA export factor
K19446 US12; Simplexvirus ICP47 protein
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K19440 UL13; Simplexvirus serine/threonine-protein kinase UL13 [EC:2.7.11.1]
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K09228 KRAB; KRAB domain-containing zinc finger protein
K06731 BST2, CD317; bone marrow stromal cell antigen 2
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K02308 DAXX; death-associated protein 6
K15413 SP100; nuclear body protein Sp100
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K05653 ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3, GRP58; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K23212 UL46; Simplexvirus tegument protein VP11/12
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K12891 SRSF2_8, SFRS2A_B; serine/arginine-rich splicing factor 2/8
K12892 SRSF3, SFRS3; serine/arginine-rich splicing factor 3
K12893 SRSF4_5_6, SFRS4_5_6; serine/arginine-rich splicing factor 4/5/6
K12896 SRSF7, SFRS7; serine/arginine-rich splicing factor 7
K21123 SRSF9, SFRS9; serine/arginine-rich splicing factor 9
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K12881 THOC4, ALY; THO complex subunit 4
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K19448 UL39; Simplexvirus ribonucleoside-diphosphate reductase large subunit [EC:1.17.4.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05135 Yersinia infection [PATH:ko05135]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02084 APAF1; apoptotic protease-activating factor
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K02161 BCL2; apoptosis regulator Bcl-2
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K08061 RFX5; regulatory factor X 5
K08062 RFXANK; regulatory factor X-associated ankyrin-containing protein
K08063 RFXAP; regulatory factor X-associated protein
K08064 NFYA, HAP2; nuclear transcription factor Y, alpha
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K08066 NFYC, HAP5; nuclear transcription factor Y, gamma
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K06752 MHC2; MHC class II antigen
K06505 CD74, DHLAG; CD74 antigen
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K10059 CLEC4E, MINCLE; C-type lectin domain family 4 member E
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K14952 namH; UDP-MurNAc hydroxylase
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K14953 lpqH; ipoprotein LpqH
K14954 lprG; lipoprotein LprG
K14955 lprA; lipoprotein LprA
K02040 pstS; phosphate transport system substrate-binding protein
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K14956 esx, esat6, cfp10; ESAT-6 family protein
K05399 LBP; lipopolysaccharide-binding protein
K10159 TLR2, CD282; toll-like receptor 2
K05398 TLR1, CD281; toll-like receptor 1
K10169 TLR6, CD286; toll-like receptor 6
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04731 IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05482 IL18, IL1F4; interleukin 18
K05426 IL23A; interleukin 23 subunit alpha
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
K10161 TLR9, CD289; toll-like receptor 9
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K06563 CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K14957 LSP1; lymphocyte-specific protein 1
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K14958 KSR1; kinase suppressor of Ras 1
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K07438 CYP27B1; calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase) [EC:1.14.15.18]
K08539 VDR, NR1I1; vitamin D3 receptor
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06462 ITGAX, CD11c; integrin alpha X
K06464 ITGB2, CD18; integrin beta 2
K06461 ITGAM, CD11b; integrin alpha M
K06560 MRC, CD206, CD280; mannose receptor, C type
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02183 CALM; calmodulin
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K12478 EEA1; early endosome antigen 1
K07897 RAB7A; Ras-related protein Rab-7A
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K06528 LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
K21302 sapM; phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K13882 CORO1A; coronin-1A
K14949 pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:ko05146]
|
K08570 EHCP; histolysain [EC:3.4.22.35]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04455 HSPB1; heat shock protein beta-1
K10955 MUC2; mucin-2
K06236 COL1A; collagen type I alpha
K06237 COL4A; collagen type IV alpha
K05717 FN1; fibronectin 1
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K13968 CP112; cysteine proteinase
K13969 ADH112; adhesin
K13970 HGL; galactose-inhibitable lectin heavy subunit
K13971 LGL; galactose-inhibitable lectin light subunit
K13972 IGL; galactose-inhibitable lectin intermediate subunit
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13973 AP; pore-forming peptide ameobapore
K06856 IGH; immunoglobulin heavy chain
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13974 EHCBP; calcium-binding protein
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13975 PATMK; phagosome-associated TMK96
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05405 IL6; interleukin 6
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K10030 IL8, CXCL8; interleukin 8
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K06448 CD1; T-cell surface glycoprotein CD1
K04687 IFNG; interferon gamma
K19720 COL3A; collagen type III alpha
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K13976 EHPAK; p21-activated kinase
K13977 EHLIMA; LIM domain-containing protein
K05700 VCL; vinculin
K05699 ACTN1_4; actinin alpha 1/4
K01476 E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
K06464 ITGB2, CD18; integrin beta 2
K06461 ITGAM, CD11b; integrin alpha M
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K13279 PRDX1; peroxiredoxin 1 [EC:1.11.1.24]
K13963 SERPINB; serpin B
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K13978 ACTNL; actinin-like protein
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K23601 SREHP; serine-rich protein
K23602 EhSTIRP; serine-threonine-isoleucine rich protein
|
05144 Malaria [PATH:ko05144]
|
K13833 SPECT; sporozoite microneme protein
K13834 SPECT2; sporozoite microneme protein 2
K13835 CELTOS; cell-traversal protein for ookinetes and sporozoites
K13836 CSP; circumsporozoite protein
K06257 SDC1, CD138; syndecan 1
K16336 SDC2, CD362; syndecan 2
K13837 TRAP; thrombospondin-related anonymous protein
K04550 LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
K06508 CD81, TAPA1, TSPAN28; CD81 antigen
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K13838 MSP1; merozoite surface protein 1
K13839 MSP2; merozoite surface protein 2
K13840 MSP3; merozoite surface protein 3
K13841 MSP4; merozoite surface protein 4
K13842 MSP5; merozoite surface protein 5
K13843 MSP6; merozoite surface protein 6
K13844 MSP8; merozoite surface protein 8
K13845 AMA-1; apical merozoite antigen 1
K13846 PVDR, DBP; Duffy binding protein
K06574 ACKR1, DARC, CD234; atypical chemokine receptor 1
K13847 EBA175; erythrocyte-binding antigen 175
K06575 GYPA, CD235a; glycophorin A
K20925 GYPB, CD235b; glycophorin B
K13848 EBA140; erythrocyte-binding antigen 140
K06576 GYPC, CD236; glycophorin C
K13849 RBP; reticulocyte-binding protein
K13822 HBA; hemoglobin subunit alpha
K13823 HBB; hemoglobin subunit beta
K13850 PFEMP1; erythrocyte membrane protein 1
K13851 RIF; repetitive interspersed family protein
K13852 STEVOR; subtelomeric variable open reading frame
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K10030 IL8, CXCL8; interleukin 8
K05405 IL6; interleukin 6
K14624 CCL2, MCP1; C-C motif chemokine 2
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K04519 IL1B; interleukin 1 beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05482 IL18, IL1F4; interleukin 18
K06543 KLRB, CD161; killer cell lectin-like receptor subfamily B
K06728 KLRK1, CD314; killer cell lectin-like receptor subfamily K member 1
K23459 KLRA4, LY49D; killer cell lectin-like receptor subfamily A member 4
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04687 IFNG; interferon gamma
K06259 CD36; CD36 antigen
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06494 SELE, CD62E; selectin, endothelial cell
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06496 SELP, CD62P; selectin, platelet
|
05145 Toxoplasmosis [PATH:ko05145]
|
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K14139 IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
K14140 IGTP; interferon gamma induced GTPase
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K14141 PFNL; profilin-like protein
K14142 TLR11; toll-like receptor 11
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K05400 LY96, MD-2; lymphocyte antigen 96
K10160 TLR4, CD284; toll-like receptor 4
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K10159 TLR2, CD282; toll-like receptor 2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06485 ITGA6, CD49f; integrin alpha 6
K05719 ITGB1, CD29; integrin beta 1
K14143 SAG; major surface antigen
K14144 MIC3; microneme protein
K13412 CPK; calcium-dependent protein kinase [EC:2.7.11.1]
K13845 AMA-1; apical merozoite antigen 1
K14145 RON2; rhoptry neck protein 2
K14146 RON4; rhoptry neck protein 4
K12473 LDLR; low-density lipoprotein receptor
K14147 GRA7; dense granule protein 7
K14148 ROP2; rhoptry protein 2
K14149 GRA3; dense granule protein 3
K14150 GRA5; dense granule protein 5
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04180 CCR5, CD195; C-C chemokine receptor type 5
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K14151 ROP16; rhoptry protein 16
K05443 IL10, CSIF; interleukin 10
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K23534 PP2CHN; protein phosphatase [EC:3.1.3.16]
|
05140 Leishmaniasis [PATH:ko05140]
|
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05430 IL4; interleukin 4
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03990 C3; complement component 3
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K06461 ITGAM, CD11b; integrin alpha M
K06464 ITGB2, CD18; integrin beta 2
K06856 IGH; immunoglobulin heavy chain
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K16824 FCGR2C, CD32; low affinity immunoglobulin gamma Fc receptor II-c
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K01404 GP63; leishmanolysin [EC:3.4.24.36]
K06483 ITGA4, CD49d; integrin alpha 4
K05719 ITGB1, CD29; integrin beta 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K08012 NCF4, P40PHOX; neutrophil cytosolic factor 4
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K06752 MHC2; MHC class II antigen
K13536 MARCKSL1, MRP; MARCKS-related protein
K13537 CPB; cysteine peptidase B [EC:3.4.22.-]
K03231 EEF1A; elongation factor 1-alpha
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
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05142 Chagas disease [PATH:ko05142]
|
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K13729 TCAC2, TC52; thiol-dependent reductase 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05415 IFNB; interferon beta
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05408 CCL3; C-C motif chemokine 3
K04519 IL1B; interleukin 1 beta
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K23590 CRP; complement regulatory protein
K03990 C3; complement component 3
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K08571 E3.4.22.51; cruzipain [EC:3.4.22.51]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K03898 KNG, BK; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K23591 TS; trans-sialidase [EC:3.2.1.-]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05429 IL2; interleukin 2
|
05143 African trypanosomiasis [PATH:ko05143]
|
K14473 VSG; variant surface glycoprotein
K06856 IGH; immunoglobulin heavy chain
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K14474 TLTF; T-lymphocyte triggering factor
K01404 GP63; leishmanolysin [EC:3.4.24.36]
K23584 SRA; resistance-associated protein
K01392 THOP1; thimet oligopeptidase [EC:3.4.24.15]
K03898 KNG, BK; kininogen
K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
K12334 NPPA; natriuretic peptide A
K13537 CPB; cysteine peptidase B [EC:3.4.22.-]
K14475 ICP; inhibitor of cysteine peptidase
K08757 APOA1; apolipoprotein A-I
K23585 APOL1; apolipoprotein L1
K14477 HPR; haptoglobin-related protein
K13822 HBA; hemoglobin subunit alpha
K13823 HBB; hemoglobin subunit beta
K14478 HPHBR; haptoglobin-hemoglobin receptor
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05482 IL18, IL1F4; interleukin 18
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K14479 EP; procyclin
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06241 LAMA4; laminin, alpha 4
K00463 IDO, INDO; indoleamine 2,3-dioxygenase [EC:1.13.11.52]
K04234 F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
|
|
09163 Immune disease
|
05310 Asthma [PATH:ko05310]
|
05322 Systemic lupus erythematosus [PATH:ko05322]
|
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K11251 H2A; histone H2A
K11252 H2B; histone H2B
K11253 H3; histone H3
K11254 H4; histone H4
K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
K11087 SNRPD1, SMD1; small nuclear ribonucleoprotein D1
K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K10651 TRIM21, SSA1; tripartite motif-containing protein 21 [EC:2.3.2.27]
K11089 TROVE2, SSA2; 60 kDa SS-A/Ro ribonucleoprotein
K11090 LA, SSB; lupus La protein
K05699 ACTN1_4; actinin alpha 1/4
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04687 IFNG; interferon gamma
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41]
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42]
K03990 C3; complement component 3
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
|
05323 Rheumatoid arthritis [PATH:ko05323]
|
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05433 IL15; interleukin 15
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K06856 IGH; immunoglobulin heavy chain
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05482 IL18, IL1F4; interleukin 18
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05426 IL23A; interleukin 23 subunit alpha
K05489 IL17A, CTLA8; interleukin 17A
K05261 PTH; parathyroid hormone
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10031 CXCL12; C-X-C motif chemokine 12
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05465 ANGPT1; angiopoietin 1
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K04687 IFNG; interferon gamma
|
05320 Autoimmune thyroid disease [PATH:ko05320]
|
05321 Inflammatory bowel disease [PATH:ko05321]
|
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05064 IL12RB2; interleukin 12 receptor beta-2
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K11222 STAT4; signal transducer and activator of transcription 4
K05429 IL2; interleukin 2
K05482 IL18, IL1F4; interleukin 18
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K04448 JUN; transcription factor AP-1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04692 STAT3; signal transducer and activator of transcription 3
K05434 IL21; interleukin 21
K05075 IL21R, CD360; interleukin 21 receptor
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K10163 FOXP3, IPEX; forkhead box P3
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05445 IL22, IL-TIF; interleukin 22
K05071 IL4R, CD124; interleukin 4 receptor
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05443 IL10, CSIF; interleukin 10
K05435 IL13; interleukin 13
K09035 CMAF, MAF; transcription factor Maf
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
|
05330 Allograft rejection [PATH:ko05330]
|
K06751 MHC1; MHC class I antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K06752 MHC2; MHC class II antigen
K05429 IL2; interleukin 2
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
|
05332 Graft-versus-host disease [PATH:ko05332]
|
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K04687 IFNG; interferon gamma
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
|
05340 Primary immunodeficiency [PATH:ko05340]
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
05417 Lipid and atherosclerosis [PATH:ko05417]
|
05418 Fluid shear stress and atherosclerosis [PATH:ko05418]
|
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1, CD138; syndecan 1
K16336 SDC2, CD362; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 TXN, trxA; thioredoxin
K12336 NPPC; natriuretic peptide C
K01940 argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD, CD141; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5, CD144; cadherin 5, type 2, VE-cadherin
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06487 ITGAV, CD51; integrin alpha V
K06493 ITGB3, CD61; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K20607 MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1, MOX1; NADPH oxidase 1
K08009 CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K08010 NCF2, P67PHOX; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K12160 SUMO, SMT3; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
|
05410 Hypertrophic cardiomyopathy [PATH:ko05410]
|
05412 Arrhythmogenic right ventricular cardiomyopathy [PATH:ko05412]
|
05414 Dilated cardiomyopathy [PATH:ko05414]
|
05415 Diabetic cardiomyopathy [PATH:ko05415]
|
05416 Viral myocarditis [PATH:ko05416]
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:ko04930]
|
04940 Type I diabetes mellitus [PATH:ko04940]
|
K04526 INS; insulin
K01580 E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
K07817 PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
K01294 CPE; carboxypeptidase E [EC:3.4.17.10]
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K19863 ICA1; islet cell auto antigen 1
K06752 MHC2; MHC class II antigen
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05429 IL2; interleukin 2
K04687 IFNG; interferon gamma
K06751 MHC1; MHC class I antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
|
04950 Maturity onset diabetes of the young [PATH:ko04950]
|
04936 Alcoholic liver disease [PATH:ko04936]
|
04932 Non-alcoholic fatty liver disease [PATH:ko04932]
|
04931 Insulin resistance [PATH:ko04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
04934 Cushing syndrome [PATH:ko04934]
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
|
09182 Protein families: genetic information processing
|
03000 Transcription factors [BR:ko03000]
|
03021 Transcription machinery [BR:ko03021]
|
03019 Messenger RNA biogenesis [BR:ko03019]
|
03041 Spliceosome [BR:ko03041]
|
03011 Ribosome [BR:ko03011]
|
03009 Ribosome biogenesis [BR:ko03009]
|
03016 Transfer RNA biogenesis [BR:ko03016]
|
03012 Translation factors [BR:ko03012]
|
03110 Chaperones and folding catalysts [BR:ko03110]
|
04131 Membrane trafficking [BR:ko04131]
|
04121 Ubiquitin system [BR:ko04121]
|
03051 Proteasome [BR:ko03051]
|
K02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]
K02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]
K02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]
K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
K02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]
K02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]
K02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]
K02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]
K02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]
K02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]
K02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]
K02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]
K02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]
K02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]
K02740 PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]
K02741 PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]
K02733 PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]
K11598 PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]
K03061 PSMC2, RPT1; 26S proteasome regulatory subunit T1
K03062 PSMC1, RPT2; 26S proteasome regulatory subunit T2
K03063 PSMC4, RPT3; 26S proteasome regulatory subunit T3
K03064 PSMC6, RPT4; 26S proteasome regulatory subunit T4
K03065 PSMC3, RPT5; 26S proteasome regulatory subunit T5
K03066 PSMC5, RPT6; 26S proteasome regulatory subunit T6
K03028 PSMD2, RPN1; 26S proteasome regulatory subunit N1
K03032 PSMD1, RPN2; 26S proteasome regulatory subunit N2
K03033 PSMD3, RPN3; 26S proteasome regulatory subunit N3
K06693 PSMD9, RPN4; 26S proteasome regulatory subunit N4
K03035 PSMD12, RPN5; 26S proteasome regulatory subunit N5
K03036 PSMD11, RPN6; 26S proteasome regulatory subunit N6
K03037 PSMD6, RPN7; 26S proteasome regulatory subunit N7
K03038 PSMD7, RPN8; 26S proteasome regulatory subunit N8
K03039 PSMD13, RPN9; 26S proteasome regulatory subunit N9
K03029 PSMD4, RPN10; 26S proteasome regulatory subunit N10
K03030 PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
K03031 PSMD8, RPN12; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5
K06694 PSMD10; 26S proteasome non-ATPase regulatory subunit 10
K06696 PSME1; proteasome activator subunit 1 (PA28 alpha)
K06697 PSME2; proteasome activator subunit 2 (PA28 beta)
K06698 PSME3; proteasome activator subunit 3 (PA28 gamma)
K06699 PSME4; proteasome activator subunit 4
K06700 PSMF1; proteasome inhibitor subunit 1 (PI31)
K11599 POMP, UMP1; proteasome maturation protein
K11875 PSMG1, DSCR2, PAC1; proteasome assembly chaperone 1
K11876 PSMG2, PAC2; proteasome assembly chaperone 2
K11877 PSMG3, PAC3; proteasome assembly chaperone 3
K11878 PSMG4, PAC4; proteasome assembly chaperone 4
K11879 PBA1, POC1; proteasome chaperone 1
K11880 ADD66, PBA2, POC2; proteasome chaperone 2
K11881 IRC25, POC3; proteasome chaperone 3
K11882 POC4; proteasome chaperone 4
K03250 EIF3E, INT6; translation initiation factor 3 subunit E
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K26598 HSPA2; heat shock 70kDa protein 2
K04079 HSP90A, htpG; molecular chaperone HtpG
K04687 IFNG; interferon gamma
K11883 NOB1; RNA-binding protein NOB1
K11884 PNO1, DIM2; RNA-binding protein PNO1
K10839 RAD23, HR23; UV excision repair protein RAD23
K04523 UBQLN, DSK2; ubiquilin
K22254 UBQLNL; ubiquilin-like protein
K11885 DDI1; DNA damage-inducible protein 1
K11886 ECM29; proteasome component ECM29
K11887 PAAF1, RPN14; proteasomal ATPase-associated factor 1
K03034 RPN4; protein RPN4
K06695 PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein
K11888 CUT8, STS1; protein Cut8
K03432 psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]
K03433 psmB, prcB; proteasome beta subunit [EC:3.4.25.1]
K13527 mpa; proteasome-associated ATPase
K13571 pafA; proteasome accessory factor A [EC:6.3.1.19]
K13572 pafB; proteasome accessory factor B
K13573 pafC; proteasome accessory factor C
K24033 pafBC; proteasome accessory factor BC
K20814 dop; Pup amidohydrolase [EC:3.5.1.119]
K03420 psmR; proteasome regulatory subunit
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03032 DNA replication proteins [BR:ko03032]
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03036 Chromosome and associated proteins [BR:ko03036]
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03400 DNA repair and recombination proteins [BR:ko03400]
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03029 Mitochondrial biogenesis [BR:ko03029]
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09183 Protein families: signaling and cellular processes
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02000 Transporters [BR:ko02000]
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02044 Secretion system [BR:ko02044]
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02042 Bacterial toxins [BR:ko02042]
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02022 Two-component system [BR:ko02022]
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02035 Bacterial motility proteins [BR:ko02035]
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03037 Cilium and associated proteins [BR:ko03037]
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04812 Cytoskeleton proteins [BR:ko04812]
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04147 Exosome [BR:ko04147]
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02048 Prokaryotic defense system [BR:ko02048]
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04030 G protein-coupled receptors [BR:ko04030]
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04050 Cytokine receptors [BR:ko04050]
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04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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04052 Cytokines and neuropeptides [BR:ko04052]
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K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10, CSIF; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K22628 IL16; interleukin 16
K05489 IL17A, CTLA8; interleukin 17A
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K05494 IL17F, ML1; interleukin 17F
K05482 IL18, IL1F4; interleukin 18
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22, IL-TIF; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K22632 IL32; interleukin 32
K12967 IL33; interleukin 33
K22633 IL34; interleukin 34
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05485 IL37, IL1F7; interleukin 37
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K27353 IFNT; interferon tau
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K06854 THPO; thrombopoietin
K05436 TSLP; thymic stromal lymphopoietin
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05407 PF4, CXCL4; platelet factor 4
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K10035 CXCL16; C-X-C motif chemokine 16
K22627 CXCL17; C-X-C motif chemokine 17
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K24191 PROK; prokineticin
K25387 GPR15L; protein GPR15L
K25418 CYTL1; cytokine-like protein 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05480 EDA; ectodysplasin-A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04384 TGFBN; transforming growth factor beta, invertebrate
K05502 BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
K21283 BMP2; bone morphogenetic protein 2
K05496 BMP3; bone morphogenetic protein 3
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K22670 BMP10; bone morphogenetic protein 10
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K05495 GDF1; growth differentiation factor 1
K05503 GDF2, BMP9; growth differentiation factor 2
K22672 GDF3; growth differentiation factor 3
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05497 MSTN, GDF8; growth differentiation factor 8
K22673 GDF9; growth differentiation factor 9
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05504 GDF15; growth differentiation factor 15
K04666 NODAL; nodal
K05500 INHA; inhibin, alpha
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K04668 LEFTY; left-right determination factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K16859 PGF; placenta growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04355 BDNF; brain-derived neurotrophic factor
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05460 HGF; hepatocyte growth factor
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K05461 KITLG; KIT ligand
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05464 GAS6; growth arrest-specific 6
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K09821 AGT, SERPINA8; angiotensinogen
K03898 KNG, BK; kininogen
K05235 NTS; neurotensin
K05225 APLN; apelin
K05223 NMB; neuromedin B
K05224 GRP; gastrin-releasing peptide
K05226 CCK; cholecystokinin
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05244 GAL; galanin
K25482 GALP; galanin-like peptide
K25694 SPX; spexin
K05254 GHRL; ghrelin
K05265 MLN; motilin
K05249 NMU; neuromedin U
K25690 NMS; neuromedin S
K05247 NPFF; neuropeptide FF-amide peptide
K25692 NPVF; pro-FMRFamide-related neuropeptide VF
K25691 NPS; neuropeptide S
K05232 NPY; neuropeptide Y
K05234 PPY; pancreatic polypeptide
K05233 PYY; peptide YY
K05267 NPB; preproneuropeptide B
K23141 NPW; neuropeptide W
K05228 POMC; proopiomelanocortin
K18832 PENK; proenkephalin A
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K25696 PNOC; prepronociceptin
K25693 QRFP; orexigenic neuropeptide QRFP
K05243 OXT; oxytocin-neurophysin 1
K05237 SST; somatostatin
K05238 CORT; cortistatin
K05239 TAC1; tachykinin 1
K05240 TAC3; tachykinin 3
K05241 TAC4; tachykinin 4
K05248 UTS2; urotensin 2
K24267 UTS2B; urotensin-2B
K05242 AVP; arginine vasopressin
K05269 PRH; Prolactin-releasing peptide
K23140 KISS1; metastasis-suppressor KiSS-1
K05246 HCRT; hypocretin (orexin) neuropeptide
K25695 VGF; neurosecretory protein VGF
K19990 CHGA; chromogranin-A
K19991 CHGB; chromogranin-B
K25732 SCG2; secretogranin-2
K25733 SCG3; secretogranin-3
K25734 SCG5; neuroendocrine protein 7B2
K05252 GNRH; gonadotropin-releasing hormone
K05253 TRH; thyrotropin-releasing hormone
K21998 RLN1_2; relaxin 1/2
K22000 RLN3; relaxin 3
K21999 INSL3; insulin-like 3
K22001 INSL5; insulin-like 5
K05229 PMCH; pro-melanin-concentrating hormone
K13768 GAST; gastrin
K12332 CALC; calcitonin
K12333 ADM; adrenomedullin
K25343 ADM2; adrenomedullin-2
K08039 IAPP; islet amyloid polypeptide
K05256 CRH; corticotropin-releasing hormone
K23142 UCN; urcortin
K05257 UCN2_3; urocortin 2/3
K05258 GIP; gastric inhibitory polypeptide
K05259 GCG; glucagon
K05260 GHRH; growth hormone-releasing hormone
K05261 PTH; parathyroid hormone
K23143 PTH2, TIP39; tuberoinfundibular peptide of 39 residues
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K05263 SCT; secretin
K05264 VIP; vasoactive intestinal peptide
K22608 PTHLH, PTHRP; parathyroid hormone-related hormone
K08522 CGA; glycoprotein hormones alpha chain
K05250 FSHB; follitropin subunit beta
K08521 LHB; lutropin subunit beta
K10045 CGB; chorionic gonadotropin, beta polypeptide
K05251 TSHB; thyrotropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12336 NPPC; natriuretic peptide C
K16656 NXPH1; neurexophilin-1
K16657 NXPH2; neurexophilin-2
K16658 NXPH3; neurexophilin-3
K25711 NXPH4; neurexophilin-4
K04526 INS; insulin
K05424 LEP; leptin
K05439 PRL; prolactin
K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein
K05231 AGRP; agouti related protein
K08762 DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
K24235 CBLN; cerebellin
K07296 ADIPOQ, ACDC; adiponectin
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K13438 RETN; resistin
K20371 NUCB; nucleobindin
K13113 UBL5, HUB1; ubiquitin-like protein 5
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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K04519 IL1B; interleukin 1 beta
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05431 IL7; interleukin 7
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12499 CCL5; C-C motif chemokine 5
K16595 CCL13; C-C motif chemokine 13
K05407 PF4, CXCL4; platelet factor 4
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K10031 CXCL12; C-X-C motif chemokine 12
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06461 ITGAM, CD11b; integrin alpha M
K06491 NCAM, CD56; neural cell adhesion molecule
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16621 BMP7; bone morphogenetic protein 7
K06224 HH; hedgehog
K11988 SHH; sonic hedgehog
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K09782 AREG; amphiregulin
K09783 BTC; betacellulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K08523 HBEGF; heparin-binding EGF-like growth factor
K05460 HGF; hepatocyte growth factor
K06828 MDK; midkine
K13769 IGF2; insulin-like growth factor 2
K05455 NRG1; neuregulin 1
K16641 HDGF; hepatoma-derived growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K16642 PTN; pleiotrophin
K05448 VEGFA; vascular endothelial growth factor A
K25640 MPIG6B; megakaryocyte and platelet inhibitory receptor G6b
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K05717 FN1; fibronectin 1
K06825 FBN1; fibrillin 1
K23342 FBN2_3; fibrillin 2/3
K06252 TN; tenascin
K24354 SMOC; SPARC-related modular calcium-binding protein
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06251 VTN; vitronectin
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
K06238 COL6A; collagen type VI alpha
K16617 COL13A; collagen type XIII alpha
K06823 COL18A; collagen type XVIII alpha
K24340 COL19A; collagen type XIX alpha
K24355 COL23A; collagen type XXIII alpha
K24356 COL25A; collagen type XXV alpha
K26586 COLQ; acetylcholinesterase collagenic tail peptide
K05462 EFNA; ephrin-A
K06843 NTN1; netrin 1
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01314 F10; coagulation factor X [EC:3.4.21.6]
K03913 SERPINA5, PCI; protein C inhibitor
K03911 SERPINC1, AT3; antithrombin III
K03912 SERPIND1, HCF2; heparin cofactor II
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K16643 SERPINE2; glia-derived nexin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03909 TFPI; tissue factor pathway inhibitor
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K19252 VP1; Dependoparvovirus capsid protein VP1/VP2/VP3
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K19264 gD; Simplexvirus envelope glycoprotein D
K19257 gM, UL10; Herpesviridae envelope glycoprotein M
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K19287 env, gp160; HIV envelope glycoprotein gp160
K24266 gp120; HIV envelope glycoprotein gp120
K19258 tat; HIV protein Tat
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K24862 gp46; HTLV envelope surface glycoprotein gp46
K19288 p130; Alphavirus structral polyprotein
K19260 L1; Papillomaviridae major capsid protein L1
K19261 F; Pneumoviridae fusion glycoprotein F0
K19262 L5; Mastadenovirus fiber protein
K19263 A27L; Orthopoxvirus protein A27
K13836 CSP; circumsporozoite protein
K15125 fhaB; filamentous hemagglutinin
K16644 actA; actin-assembly inducing protein
K16645 hbhA; heparin binding hemagglutinin HbhA
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K16646 ANXA5; annexin A5
K09025 APOA5; apolipoprotein A-V
K14462 APOB; apolipoprotein B
K04524 APOE; apolipoprotein E
K04520 APP; amyloid beta A4 protein
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K05634 PRNP, PrP, CD230; prion protein
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06256 CD44; CD44 antigen
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10077 LAYN; layilin
K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K19031 CEMIP, KIAA1199; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
K06792 AGC1, CSPG1; aggrecan 1
K06795 BCAN; brevican
K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
K06848 HAPLN1, CRTL1; hyaluronan and proteoglycan link protein 1
K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
K18977 HPX; hemopexin
K19014 ITIH1, SHAP; inter-alpha-trypsin inhibitor heavy chain H1
K19015 ITIH2, SHAP; inter-alpha-trypsin inhibitor heavy chain H2
K24513 ITIH3, SHAP; inter-alpha-trypsin inhibitor heavy chain H3
K06794 NCAN, CSPG3; neurocan core protein
K19016 IMPG1, SPACR; interphotoreceptor matrix proteoglycan 1
K19017 IMPG2, SPACRCAN; interphotoreceptor matrix proteoglycan 2
K19018 TNFAIP6, TSG6; tumor necrosis factor-inducible gene 6 protein
K06793 VCAN, CSPG2; versican core protein
K09554 CDC37; cell division cycle protein 37
K19019 HABP4; intracellular hyaluronan-binding protein 4
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)