KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
       K00431  TPO; thyroid peroxidase [EC:1.11.1.8]
       K05437  EPO; erythropoietin
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K04687  IFNG; interferon gamma
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05440  IFNW1; interferon, omega 1
       K05441  IFNK; interferon, kappa
       K05442  IFNT1; interferon, tau-1
       K05443  IL10, CSIF; interleukin 10
       K05444  IL19_20_24; interleukin 19/20/24
       K05445  IL22, IL-TIF; interleukin 22
       K05446  IL26; interleukin 26
       K05447  IL28_29, IFNL; interleukin 28/29 (interferon, lambda)
       K04736  IL3; interleukin 3
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05428  IL5; interleukin 5
       K05429  IL2; interleukin 2
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05432  IL9; interleukin 9
       K05433  IL15; interleukin 15
       K05434  IL21; interleukin 21
       K05435  IL13; interleukin 13
       K05436  TSLP; thymic stromal lymphopoietin
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05417  IL11; interleukin 11
       K05418  OSM; oncostatin M
       K05419  LIF; leukemia inhibitory factor
       K05420  CNTF; ciliary neurotrophic factor
       K05421  BSF3, CLC; B-cell stimulating factor 3
       K05422  CTF1, CT1; cardiotrophin 1
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05424  LEP; leptin
       K05425  IL12B; interleukin 12B
       K05426  IL23A; interleukin 23, alpha subunit p19
       K04737  IL3RA; interleukin 3 receptor alpha
       K04738  CSF2RB, IL3RB; cytokine receptor common subunit beta
       K05055  IL6R; interleukin 6 receptor
       K05056  IL11RA; interleukin 11 receptor alpha
       K05057  OSMR; oncostatin M receptor
       K05058  LIFR; leukemia inhibitory factor receptor
       K05059  CNTFR; ciliary neurotrophic factor receptor
       K05060  IL6ST, GP130; interleukin 6 signal transducer
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05062  LEPR; leptin receptor
       K05063  IL12RB1; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05065  IL23R; interleukin 23 receptor
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05067  IL5RA; interleukin 5 receptor alpha
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K05071  IL4R; interleukin 4 receptor
       K05072  IL7R; interleukin 7 receptor
       K05073  IL9R; interleukin 9 receptor
       K05074  IL15RA; interleukin 15 receptor alpha
       K05075  IL21R; interleukin 21 receptor
       K05076  IL13RA1; interleukin 13 receptor alpha-1
       K05077  IL13RA2; interleukin 13 receptor alpha-2
       K05078  TSLPR; thymic stromal-derived lymphopoietin receptor
       K05079  EPOR; erythropoietin receptor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05082  TPOR, MPL; thrombopoietin receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K05136  IL20RA; interleukin 20 receptor alpha
       K05137  IL20RB; interleukin 20 receptor beta
       K05138  IL22RA1; interleukin 22 receptor alpha 1
       K05139  IL22RA2; interleukin 22 receptor alpha 2
       K05140  IL28RA; interleukin 28 receptor alpha
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04692  STAT3; signal transducer and activator of transcription 3
       K11222  STAT4; signal transducer and activator of transcription 4
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11225  STAT6; signal transducer and activator of transcription 6
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K04698  SOCS5; suppressor of cytokine signaling 5
       K04699  SOCS7, NAP4; suppressor of cytokine signaling 7
       K04700  SOCSN; suppressor of cytokine signaling, invertebrate
       K04701  CISH; cytokine inducible SH2-containing protein
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K04703  SPRED; sprouty-related, EVH1 domain-containing protein
       K04704  SPRY1; protein sprouty homolog 1
       K17383  SPRY2; protein sprouty homolog 2
       K17385  SPRY4; protein sprouty homolog 4
       K04705  STAM; signal transducing adaptor molecule
       K04706  PIAS1; E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-]
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K16064  PIAS3; E3 SUMO-protein ligase PIAS3 [EC:6.3.2.-]
       K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2; toll-like receptor 2
       K10160  TLR4; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; CD19 antigen
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K04737  IL3RA; interleukin 3 receptor alpha
       K05055  IL6R; interleukin 6 receptor
       K05071  IL4R; interleukin 4 receptor
       K05072  IL7R; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K06626  CCNE; cyclin E
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; BCL2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB; myb proto-oncogene protein
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
     04030 G protein-coupled receptors [BR:ko04030]
     01020 Enzyme-linked receptors [BR:ko01020]
     04050 Cytokine receptors [BR:ko04050]
     03310 Nuclear receptors [BR:ko03310]
     04040 Ion channels [BR:ko04040]
     04031 GTP-binding proteins [BR:ko04031]
     04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04132  CHRM4; muscarinic acetylcholine receptor M4
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K04134  CHRMN; muscarinic acetylcholine receptor
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04138  ADRA2A; adrenergic receptor alpha-2A
       K04139  ADRA2B; adrenergic receptor alpha-2B
       K04140  ADRA2C; adrenergic receptor alpha-2C
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04144  DRD1; dopamine receptor D1
       K04145  DRD2; dopamine receptor D2
       K04146  DRD3; dopamine receptor D3
       K04147  DRD4; dopamine receptor D4
       K05840  DRD5; dopamine receptor D5
       K04148  DRD1N, DopR; dopamine D1-like receptor
       K14049  DRD2N; dopamine D2-like receptor
       K04149  HRH1; histamine receptor H1
       K04150  HRH2; histamine receptor H2
       K04151  HRH3; histamine receptor H3
       K04152  HRH4; histamine receptor H4
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04161  HTR5; 5-hydroxytryptamine receptor 5
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K05051  TAAR; trace amine associated receptor
       K04166  AGTR1; angiotensin II receptor type 1
       K04167  AGTR2; angiotensin II receptor type 2
       K05223  NMB; neuromedin B
       K05224  GRP; gastrin-releasing peptide
       K04168  NMBR; neuromedin B receptor
       K04169  GRPR; gastrin-releasing peptide receptor
       K04170  BRS3; bombesin-like receptor 3
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04010  C5AR1; C5a anaphylatoxin chemotactic receptor
       K04009  C3AR1; C3a anaphylatoxin chemotactic receptor
       K04171  GPR77; G protein-coupled receptor 77
       K04172  FPR1; formyl peptide receptor 1
       K04173  FPRL; formyl peptide receptor-like
       K05225  APLN; apelin
       K04174  APLNR; apelin receptor
       K05226  CCK; cholecystokinin
       K04194  CCKAR; cholecystokinin A receptor
       K04195  CCKBR; cholecystokinin B receptor
       K04196  CCKLR; cholecystokinin-like receptor
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K05228  POMC; proopiomelanocortin
       K05231  AGRP; agouti related protein
       K04199  MC1R; melanocortin 1 receptor
       K04200  MC2R; melanocortin 2 receptor
       K04201  MC3R; melanocortin 3 receptor
       K04202  MC4R; melanocortin 4 receptor
       K04203  MC5R; melanocortin 5 receptor
       K05232  NPY; neuropeptide Y
       K04204  NPY1R_4R_6R; neuropeptide Y receptor type 1/4/6
       K04205  NPY2R; neuropeptide Y receptor type 2
       K04207  NPY5R; neuropeptide Y receptor type 5
       K04209  NPYNR; neuropeptide Y receptor, invertebrate
       K04210  GPR83, GPR72; G protein-coupled receptor 83
       K05233  PYY; peptide YY
       K05234  PPY; pancreatic polypeptide
       K05235  NTS; neurotensin
       K05236  COPA; coatomer protein complex, subunit alpha (xenin)
       K04211  NTSR1; neurotensin receptor 1
       K04212  NTSR2; neurotensin receptor 2
       K04213  OPRD1; delta-type opioid receptor
       K04214  OPRK1; kappa-type opioid receptor
       K04215  OPRM1; mu-type opioid receptor
       K04216  OPRL1; nociceptin receptor
       K05237  SST; somatostatin
       K05238  CORT; cortistatin
       K04217  SSTR1; somatostatin receptor 1
       K04218  SSTR2; somatostatin receptor 2
       K04219  SSTR3; somatostatin receptor 3
       K04220  SSTR4; somatostatin receptor 4
       K04221  SSTR5; somatostatin receptor 5
       K05239  TAC1; tachykinin 1
       K05240  TAC2_3; tachykinin 2/3
       K05241  TAC4; tachykinin 4
       K04222  TACR1; tachykinin receptor 1
       K04223  TACR2; tachykinin receptor 2
       K04224  TACR3; tachykinin receptor 3
       K04225  TAKR; tachykinin-like receptor
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04228  AVPR2; arginine vasopressin receptor 2
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K05244  GAL; galanin
       K04230  GALR1; galanin receptor 1
       K04231  GALR2; galanin receptor 2
       K04232  GALR3; galanin receptor 3
       K04233  GALRN, AR; allatostatin receptor
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K01319  CTSG; cathepsin G [EC:3.4.21.20]
       K01352  GZMA; granzyme A [EC:3.4.21.78]
       K01315  PLG; plasminogen [EC:3.4.21.7]
       K01312  PRSS; trypsin [EC:3.4.21.4]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
       K04235  F2RL2, PAR3; coagulation factor II (thrombin) receptor-like 2
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04237  PARD3; partitioning defective protein 3
       K05246  HCRT; hypocretin (orexin) neuropeptide
       K04238  HCRTR1; hypocretin (orexin) receptor 1
       K04239  HCRTR2; hypocretin (orexin) receptor 2
       K05247  NPFF; neuropeptide FF-amide peptide
       K04240  NPFFR1; neuropeptide FF receptor 1
       K08375  NPFFR2; neuropeptide FF receptor 2
       K05248  UTS2; urotensin 2
       K04241  UTS2R; urotensin 2 receptor
       K05249  NMU; neuromedin U
       K05052  NMUR1; neuromedin U receptor 1
       K05053  NMUR2; neuromedin U receptor 2
       K04320  MCHR1; melanin-concentrating hormone receptor 1
       K05054  MCHR2; melanin-concentrating hormone receptor 2
       K05250  FSH; follicle stimulating hormone
       K04247  FSHR; follicle stimulating hormone receptor
       K05251  TSHB; thyroid stimulating hormone, beta
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K04249  TSHR; thyroid stimulating hormone receptor
       K04332  PTGDR; prostaglandin D2 receptor
       K04258  PTGER1; prostaglandin E receptor 1
       K04259  PTGER2; prostaglandin E receptor 2
       K04260  PTGER3; prostaglandin E receptor 3
       K04261  PTGER4; prostaglandin E receptor 4
       K04262  PTGFR; prostaglandin F receptor
       K04263  PTGIR; prostacyclin receptor
       K04264  TBXA2R; thromboxane A2 receptor
       K04265  ADORA1; adenosine A1 receptor
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04268  ADORA3; adenosine A3 receptor
       K04269  P2RY2; purinergic receptor P2Y, G protein-coupled, 2
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04271  P2RY4; pyrimidinergic receptor P2Y, G protein-coupled, 4
       K04272  P2RY6; pyrimidinergic receptor P2Y, G protein-coupled, 6
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04274  P2RY10; purinergic receptor P2Y, G protein-coupled, 10
       K04299  P2RY14; purinergic receptor P2Y, G protein-coupled, 14
       K08386  P2RY8; purinergic receptor P2Y, G protein-coupled, 8
       K08387  P2RY11; purinergic receptor P2Y, G protein-coupled, 11
       K08388  P2RY13; purinergic receptor P2Y, G protein-coupled, 13
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K04276  GPR35; G protein-coupled receptor 35
       K04277  CNR1; cannabinoid receptor 1
       K04278  CNR2; cannabinoid receptor 2 (macrophage)
       K04279  PTAFR; platelet-activating factor receptor
       K05252  GNRH; gonadotropin-releasing hormone
       K04280  GNRHR; gonadotropin-releasing hormone receptor
       K05253  TRH; thyrotropin-releasing hormone
       K04282  TRHR; thyrotropin-releasing hormone receptor
       K05254  GHRL; ghrelin
       K04284  GHSR; growth hormone secretagogue receptor
       K08374  KISS1R; KISS1 receptor
       K04285  MTNR1A; melatonin receptor type 1A
       K04286  MTNR1B; melatonin receptor type 1B
       K04287  GPR50; G protein-coupled receptor 50
       K04288  S1PR1, EDG1; sphingosine 1-phosphate receptor 1
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04290  S1PR3, EDG3; sphingosine 1-phosphate receptor 3
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04292  S1PR2, EDG5; sphingosine 1-phosphate receptor 2
       K04293  S1PR4, EDG6; sphingosine 1-phosphate receptor 4
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04295  S1PR5, EDG8; sphingosine 1-phosphate receptor 5
       K04296  LTB4R1; leukotriene B4 receptor 1
       K04297  LTB4R2; leukotriene B4 receptor 2
       K04303  MAS1; MAS1 oncogene
       K04306  LGR7; leucine-rich repeat-containing G protein-coupled receptor 7
       K04307  LGR8; leucine-rich repeat-containing G protein-coupled receptor 8
       K04308  LGR5, GPR49; leucine-rich repeat-containing G protein-coupled receptor 5
       K04309  LGR4, GPR48; leucine-rich repeat-containing G protein-coupled receptor 4
       K04322  CYSLTR1; cysteinyl leukotriene receptor 1
       K04323  CYSLTR2; cysteinyl leukotriene receptor 2
       K04576  CALCR; calcitonin receptor
       K04577  CALCRL; calcitonin receptor-like
       K05256  CRH; corticotropin-releasing hormone
       K05257  UCN2_3; urocortin 2/3
       K04578  CRHR1; corticotropin releasing hormone receptor 1
       K04579  CRHR2; corticotropin releasing hormone receptor 2
       K05258  GIP; gastric inhibitory polypeptide
       K04580  GIPR; gastric inhibitory polypeptide receptor
       K05259  GCG; glucagon
       K04581  GLP1R; glucagon-like peptide 1 receptor
       K04582  GLP2R; glucagon-like peptide 2 receptor
       K04583  GCGR; glucagon receptor
       K05260  GHRH; growth hormone-releasing hormone
       K04584  GHRHR; growth hormone releasing hormone receptor
       K05261  PTH; parathyroid hormone
       K04585  PTHR1; parathyroid hormone receptor 1
       K04586  PTHR2; parathyroid hormone receptor 2
       K05262  ADCYAP; adenylate cyclase activating polypeptide
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K05263  SCT; secretin
       K04588  SCTR; secretin receptor
       K05264  VIP; vasoactive intestinal peptide
       K04589  VIPR1; vasoactive intestinal peptide receptor 1
       K04590  VIPR2; vasoactive intestinal peptide receptor 2
       K04603  GRM1; metabotropic glutamate receptor 1
       K04605  GRM2_3; metabotropic glutamate receptor 2/3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04604  GRM5; metabotropic glutamate receptor 5
       K04608  GRM6_7_8; metabotropic glutamate receptor 6/7/8
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04617  GPR156, GABABL; gamma-aminobutyric acid type B receptor-like
       K05265  MLN; motilin
       K05266  MLNR; motilin receptor
       K05267  NPB; preproneuropeptide B
       K05268  NPBWR1; neuropeptides B/W receptor 1
       K08377  NPBWR2; neuropeptides B/W receptor 2
       K05269  PRH; Prolactin-releasing peptide
       K04314  PRLHR, GPR10; prolactin releasing hormone receptor
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K05175  GABRA; gamma-aminobutyric acid receptor subunit alpha
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K05184  GABRD; gamma-aminobutyric acid receptor subunit delta
       K05185  GABRE; gamma-aminobutyric acid receptor subunit epsilon
       K05186  GABRG; gmma-aminobutyric acid receptor subunit gamma
       K05189  GABRP; gamma-aminobutyric acid receptor subunit pi
       K05190  GABRR; gamma-aminobutyric acid receptor subunit rho
       K05192  GABRQ; gamma-aminobutyric acid receptor subunit theta
       K04803  CHRNA1; nicotinic acetylcholine receptor alpha-1
       K04804  CHRNA2; nicotinic acetylcholine receptor alpha-2
       K04805  CHRNA3; nicotinic acetylcholine receptor alpha-3
       K04806  CHRNA4; nicotinic acetylcholine receptor alpha-4
       K04807  CHRNA5; nicotinic acetylcholine receptor alpha-5
       K04808  CHRNA6; nicotinic acetylcholine receptor alpha-6
       K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
       K04810  CHRNA9; nicotinic acetylcholine receptor alpha-9
       K04811  CHRNA10; nicotinic acetylcholine receptor alpha-10
       K04812  CHRNB1; nicotinic acetylcholine receptor beta-1
       K04813  CHRNB2; nicotinic acetylcholine receptor beta-2
       K04814  CHRNB3; nicotinic acetylcholine receptor beta-3
       K04815  CHRNB4; nicotinic acetylcholine receptor beta-4
       K04816  CHRND; nicotinic acetylcholine receptor delta
       K04817  CHRNE; nicotinic acetylcholine receptor epsilon
       K04818  CHRNG; nicotinic acetylcholine receptor gamma
       K05215  P2RX1; P2X purinoceptor 1
       K05216  P2RX2; P2X purinoceptor 2
       K05217  P2RX3; P2X purinoceptor 3
       K05218  P2RX4; P2X purinoceptor 4
       K05219  P2RX5; P2X purinoceptor 5
       K05220  P2RX7; P2X purinoceptor 7
       K05221  P2RX6, P2RXL1; P2X purinoceptor 6
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K08521  LHB; luteinizing hormone beta polypeptide
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05201  GRIK1; glutamate receptor, ionotropic kainate 1
       K05202  GRIK2; glutamate receptor, ionotropic kainate 2
       K05203  GRIK3; glutamate receptor, ionotropic kainate 3
       K05204  GRIK4; glutamate receptor, ionotropic kainate 4
       K05205  GRIK5; glutamate receptor, ionotropic kainate 5
       K05206  GRID1; glutamate receptor delta-1 subunit
       K05207  GRID2; glutamate receptor delta-2 subunit
       K05193  GLRA1; glycine receptor alpha-1
       K05194  GLRA2; glycine receptor alpha-2
       K05195  GLRA3; glycine receptor alpha-3
       K05196  GLRB; glycine receptor beta
       K05222  TRPV1; transient receptor potential cation channel subfamily V member 1
       K05770  BZRP; benzodiazapine receptor
       K05771  NR3C1, GR; glucocorticoid receptor
       K05438  GH; growth hormone
       K05080  GHR; growth hormone receptor
       K05547  NR1A1, THRA; thyroid hormone receptor alpha
       K08362  NR1A2, THRB; thyroid hormone receptor beta
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K05439  PRL; prolactin
       K05081  PRLR; prolactin receptor
     04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10029  PPBP, CXCL7; platelet basic protein
       K10030  IL8, CXCL8; interleukin 8
       K05416  CXCL9; C-X-C motif chemokine 9
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K12672  CXCL11, I-TAC; C-X-C motif chemokine 11
       K10031  CXCL12; C-X-C motif chemokine 12
       K10032  CXCL13; C-X-C motif chemokine 13
       K10035  CXCL16; C-X-C motif chemokine 16
       K10034  CXCL15; C-X-C motif chemokine 15
       K05407  PF4, CXCL4; platelet factor 4
       K10033  CXCL14, SCYB14; C-X-C motif chemokine 14
       K05507  XCL, SCM1; C motif chemokine 1/2
       K05508  CX3CL1, NTT; C-X3-C motif chemokine 1
       K05514  CCLX; C-C motif chemokine, other
       K14625  CCL20; C-C motif chemokine 20
       K13072  CCL25; C-C motif chemokine 25
       K05512  CCL19, ELC; C-C motif chemokine 19
       K16062  CCL21, SLC; C-C motif chemokine 21
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12964  CCL4; C-C motif chemokine 4
       K05408  CCL3; C-C motif chemokine 3
       K16595  CCL13; C-C motif chemokine 13
       K05509  CCL7; C-C motif chemokine 7
       K12499  CCL5; C-C motif chemokine 5
       K05511  CCL15_23; C-C motif chemokine 15/23
       K16596  CCL8; C-C motif chemokine 8
       K16597  CCL11; C-C motif chemokine 11
       K05513  CCL28; C-C motif chemokine 28
       K16598  CCL27; C-C motif chemokine 27
       K05510  CCL6_9; C-C motif chemokine 6/9
       K05405  IL6; interleukin 6
       K05417  IL11; interleukin 11
       K05418  OSM; oncostatin M
       K05419  LIF; leukemia inhibitory factor
       K05420  CNTF; ciliary neurotrophic factor
       K05421  BSF3, CLC; B-cell stimulating factor 3
       K05422  CTF1, CT1; cardiotrophin 1
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05424  LEP; leptin
       K05430  IL4; interleukin 4
       K05435  IL13; interleukin 13
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05426  IL23A; interleukin 23, alpha subunit p19
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04736  IL3; interleukin 3
       K05428  IL5; interleukin 5
       K05429  IL2; interleukin 2
       K05431  IL7; interleukin 7
       K05432  IL9; interleukin 9
       K05433  IL15; interleukin 15
       K05434  IL21; interleukin 21
       K05436  TSLP; thymic stromal lymphopoietin
       K05437  EPO; erythropoietin
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K00431  TPO; thyroid peroxidase [EC:1.11.1.8]
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K04357  EGF; epidermal growth factor
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05440  IFNW1; interferon, omega 1
       K05441  IFNK; interferon, kappa
       K05442  IFNT1; interferon, tau-1
       K04687  IFNG; interferon gamma
       K05443  IL10, CSIF; interleukin 10
       K05444  IL19_20_24; interleukin 19/20/24
       K05445  IL22, IL-TIF; interleukin 22
       K05447  IL28_29, IFNL; interleukin 28/29 (interferon, lambda)
       K05446  IL26; interleukin 26
       K05478  TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
       K04721  TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05474  TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K05477  TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
       K05470  TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
       K05471  TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
       K05472  TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
       K05469  TNFSF4, OX40L; tumor necrosis factor ligand superfamily member 4
       K05479  TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
       K05475  TNFSF13, APRIL; tumor necrosis factor ligand superfamily member 13
       K05476  TNFSF13B, TNFSF20; tumor necrosis factor ligand superfamily member 13B
       K05480  EDA; ectodysplasin-A
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04667  INHB; inhibin, beta
       K04665  AMH; anti-mullerian hormone
       K04662  BMP2_4; bone morphogenetic protein 2/4
       K16621  BMP7; bone morphogenetic protein 7
       K04664  GDF5_6_7; growth differentiation factor 5/6/7
       K05489  IL17, CTLA8; interleukin 17
       K05490  IL17B, CX1; interleukin 17B
       K05493  IL17E, IL25; interleukin 17E
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K05482  IL18, IL1F4; interleukin 18
       K05050  IL8RB, CXCR2; interleukin 8 receptor beta
       K04175  IL8RA, CXCR1; interleukin 8 receptor alpha
       K04188  CXCR3, GPR9; C-X-C chemokine receptor type 3
       K04189  CXCR4; C-X-C chemokine receptor type 4
       K04190  CXCR5, BLR1; C-X-C chemokine receptor type 5
       K04191  CXCR6; C-X-C chemokine receptor type 6
       K04304  CXCR7, RDC1; C-X-C chemokine receptor type 7
       K04193  XCR1; XC chemokine receptor 1
       K04192  CX3CR1; CX3C chemokine receptor 1
       K04183  CCR8; C-C chemokine receptor type 8
       K04181  CCR6; C-C chemokine receptor type 6
       K04184  CCR9; C-C chemokine receptor type 9
       K04179  CCR4; C-C chemokine receptor type 4
       K04182  CCR7; C-C chemokine receptor type 7
       K04177  CCR2; C-C chemokine receptor type 2
       K04180  CCR5; C-C chemokine receptor type 5
       K04176  CCR1; C-C chemokine receptor type 1
       K04178  CCR3; C-C chemokine receptor type 3
       K04185  CCR10; C-C chemokine receptor type 10
       K05055  IL6R; interleukin 6 receptor
       K05060  IL6ST, GP130; interleukin 6 signal transducer
       K05056  IL11RA; interleukin 11 receptor alpha
       K05058  LIFR; leukemia inhibitory factor receptor
       K05057  OSMR; oncostatin M receptor
       K05059  CNTFR; ciliary neurotrophic factor receptor
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05062  LEPR; leptin receptor
       K05071  IL4R; interleukin 4 receptor
       K05076  IL13RA1; interleukin 13 receptor alpha-1
       K05063  IL12RB1; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05065  IL23R; interleukin 23 receptor
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K04738  CSF2RB, IL3RB; cytokine receptor common subunit beta
       K04737  IL3RA; interleukin 3 receptor alpha
       K05067  IL5RA; interleukin 5 receptor alpha
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K05072  IL7R; interleukin 7 receptor
       K05073  IL9R; interleukin 9 receptor
       K05074  IL15RA; interleukin 15 receptor alpha
       K05075  IL21R; interleukin 21 receptor
       K05078  TSLPR; thymic stromal-derived lymphopoietin receptor
       K05079  EPOR; erythropoietin receptor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05082  TPOR, MPL; thrombopoietin receptor
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K05136  IL20RA; interleukin 20 receptor alpha
       K05137  IL20RB; interleukin 20 receptor beta
       K05138  IL22RA1; interleukin 22 receptor alpha 1
       K05139  IL22RA2; interleukin 22 receptor alpha 2
       K05140  IL28RA; interleukin 28 receptor alpha
       K04722  TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
       K05148  TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K05160  TNFRSF25; tumor necrosis factor receptor superfamily member 25
       K05149  TNFRSF12A, FN14, TWEAKR; tumor necrosis factor receptor superfamily member 12A
       K05157  TNFRSF21, DR6; tumor necrosis factor receptor superfamily member 21
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K05152  TNFRSF14, HVEM; tumor necrosis factor receptor superfamily member 14
       K05143  TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05144  TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
       K05145  TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
       K05146  TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
       K05142  TNFRSF4, OX40; tumor necrosis factor receptor superfamily member 4
       K05154  TNFRSF18, GITR; tumor necrosis factor receptor superfamily member 18
       K05153  TNFRSF17, BCMA; tumor necrosis factor receptor superfamily member 17
       K05150  TNFRSF13B, TACI; tumor necrosis factor receptor superfamily member 13B
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K05162  EDAR; tumor necrosis factor receptor superfamily member EDAR
       K05163  EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
       K05155  TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
       K05156  TNFRSF19L, RELT; tumor necrosis factor receptor superfamily member 19-like
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04670  ACVR2A; activin receptor type-2A [EC:2.7.11.30]
       K13596  ACVR2B; activin receptor type-2B [EC:2.7.11.30]
       K04675  ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
       K13567  ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
       K04672  AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K04673  BMPR1A, ALK3; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
       K13578  BMPR1B, ALK6; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
       K05164  IL17R; interleukin 17 receptor
       K05165  IL17RB, IL17RH1; interleukin 17 receptor B
       K04386  IL1R1; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04387  IL1R2; interleukin 1 receptor type II
       K05173  IL18R1, IL1RRP; interleukin 18 receptor 1
       K05174  IL18RAP, ACPL; interleukin 18 receptor accessory protein
     04052 Cytokines [BR:ko04052]
     04512 ECM-receptor interaction [PATH:ko04512]
     04514 Cell adhesion molecules (CAMs) [PATH:ko04514]
     04516 Cell adhesion molecules and their ligands [BR:ko04516]
     04090 CD Molecules [BR:ko04090]
     04091 Lectins [BR:ko04091]
     02042 Bacterial toxins [BR:ko02042]
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
       K05439  PRL; prolactin
       K05081  PRLR; prolactin receptor
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K09408  FOXO3; forkhead box protein O3
       K00965  galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04503  CCND1; cyclin D1
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K04701  CISH; cytokine inducible SH2-containing protein
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K04698  SOCS5; suppressor of cytokine signaling 5
       K10322  SOCS6, CIS4; suppressor of cytokine signaling 6
       K04699  SOCS7, NAP4; suppressor of cytokine signaling 7
       K11220  STAT1; signal transducer and activator of transcription 1
       K04692  STAT3; signal transducer and activator of transcription 3
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K17106  WAP; whey acidic protein
       K17101  ELF5; E74-like factor 5
       K17107  CSN2; beta-casein
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K08521  LHB; luteinizing hormone beta polypeptide
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K00512  CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.99.9 4.1.2.30]
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K08551  NR3A2, ESR2; estrogen receptor beta
       K09444  IRF1; interferon regulatory factor 1
       K00501  TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
       K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K10151  CCND2; cyclin D2
       K04526  INS; insulin
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases

[ BRITE | KEGG2 | KEGG ]
Last updated: April 20, 2014