KEGG Orthology (KO)

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 Human Diseases
 
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   Immune diseases
 
   Neurodegenerative diseases
     05010 Alzheimer's disease [PATH:ko05010]
     05012 Parkinson's disease [PATH:ko05012]
     05014 Amyotrophic lateral sclerosis (ALS) [PATH:ko05014]
     05016 Huntington's disease [PATH:ko05016]
       K04644  CLTA, LCA; clathrin light chain A
       K04645  CLTB, LCB; clathrin light chain B
       K04646  CLTC; clathrin heavy chain
       K04559  HIP1; huntingtin interacting protein 1
       K11824  AP2A; AP-2 complex subunit alpha
       K11825  AP2B1; AP-2 complex subunit beta-1
       K11826  AP2M1; AP-2 complex subunit mu-1
       K11827  AP2S1; AP-2 complex subunit sigma-1
       K04533  HD; huntingtin
       K04638  ESRRBL1, HIPPI; estrogen-related receptor beta like 1
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04604  GRM5; metabotropic glutamate receptor 5
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K11828  DLG4, PSD95; discs large protein 4
       K05625  TGM2; transglutaminase 2 [EC:2.3.2.13]
       K09222  REST; RE1-silencing transcription factor
       K11644  SIN3A; paired amphipathic helix protein Sin3a
       K11829  RCOR1, COREST; REST corepressor 1
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K04355  BDNF; brain-derived neurotrophic factor
       K04648  DCTN1; dynactin 1
       K10424  DCTN2; dynactin 2
       K10426  DCTN4; dynactin 4
       K04647  HAP1; huntingtin-associated protein 1
       K10408  DNAH; dynein heavy chain, axonemal
       K10410  DNALI; dynein light intermediate chain, axonemal
       K10409  DNAI1; dynein intermediate chain 1, axonemal
       K11143  DNAI2; dynein intermediate chain 2, axonemal
       K10411  DNAL1; dynein light chain 1, axonemal
       K10412  DNAL4; dynein light chain 4, axonemal
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K03129  TAF4; transcription initiation factor TFIID subunit 4
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04684  SP1; transcription factor Sp1
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K11830  TFAM, MTTFA; transcription factor A, mitochondrial
       K11831  NRF1; nuclear respiratory factor 1
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K08769  UCP1, SLC25A7; solute carrier family 25 (mitochondrial uncoupling protein), member 7
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K10132  BBC3, PUMA; BCL2-binding component 3
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
       K02132  ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
       K02133  ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
       K02136  ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
       K02134  ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
       K02135  ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
       K02126  ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
       K02127  ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
       K02128  ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
       K02138  ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
       K02137  ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
       K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
       K02125  ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
     05020 Prion diseases [PATH:ko05020]
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

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Last updated: October 29, 2014