KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
       K07362  LAT; linker for activation of T cells
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K07371  BLNK; B-cell linker protein
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07367  CARD11; caspase recruitment domain-containing protein 11
       K07368  BCL10; B-cell CLL/lymphoma 10
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2
       K09849  TRAF5; TNF receptor-associated factor 5
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K10652  TRIM25, EFP; tripartite motif-containing protein 25 [EC:6.3.2.19]
       K05399  LBP; lipopolysaccharide-binding protein
       K04391  CD14; CD14 antigen
       K10160  TLR4; toll-like receptor 4
       K05400  LY96, MD-2; lymphocyte antigen 96
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05842  TRIF; toll-like receptor adapter molecule 1
       K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K03174  TRAF3; TNF receptor-associated factor 3
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K03157  LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
       K05477  TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K05476  TNFSF13B, TNFSF20; tumor necrosis factor ligand superfamily member 13B
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-]
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K10130  LRDD, PIDD; leucine-rich repeats and death domain-containing protein
       K16072  ERC1; ELKS/RAB6-interacting/CAST family member 1
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K03172  TRAF1; TNF receptor-associated factor 1
       K02162  BCL2A1; hematopoietic BCL2-related protein A1
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K10030  IL8, CXCL8; interleukin 8
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K12964  CCL4; C-C motif chemokine 4
       K06527  VCAM1; vascular cell adhesion molecule 1
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K09253  RELB; transcription factor RelB
       K16595  CCL13; C-C motif chemokine 13
       K05512  CCL19, ELC; C-C motif chemokine 19
       K16062  CCL21, SLC; C-C motif chemokine 21
       K10031  CXCL12; C-X-C motif chemokine 12
       K06490  ICAM1; intercellular adhesion molecule 1
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2; toll-like receptor 2
       K10160  TLR4; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; CD19 antigen
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K04737  IL3RA; interleukin 3 receptor alpha
       K05055  IL6R; interleukin 6 receptor
       K05071  IL4R; interleukin 4 receptor
       K05072  IL7R; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K06626  CCNE; cyclin E
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; BCL2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB; myb proto-oncogene protein
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
       K04264  TBXA2R; thromboxane A2 receptor
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12757  MYL12; myosin regulatory light chain 12
       K05215  P2RX1; P2X purinoceptor 1
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K16059  STIM1; stromal interaction molecule 1
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K17704  APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
       K06271  TLN; talin
       K06476  ITGA2B; integrin alpha 2B
       K06493  ITGB3; integrin beta 3
       K17084  FERMT3, KIND3; kindlin 3
       K03903  FGA; fibrinogen alpha chain
       K03904  FGB; fibrinogen beta chain
       K03905  FGG; fibrinogen gamma chain
       K04298  P2RY12; purinergic receptor P2Y, G protein-coupled, 12
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04263  PTGIR; prostacyclin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05692  ACTB_G1; actin beta/gamma 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05732  GRLF1; glucocorticoid receptor DNA-binding factor 1
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06264  GP6; platelet glycoprotein VI
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06481  ITGA2; integrin alpha 2
       K05719  ITGB1; integrin beta 1
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K03900  VWF; von Willebrand factor
       K06260  GP5; platelet glycoprotein V
       K06261  GP1BA; platelet glycoprotein Ib alpha chain
       K06262  GP1BB; platelet glycoprotein Ib beta chain
       K06263  GP9; platelet glycoprotein IX
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K01832  TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
       K08508  SNAP23; synaptosomal-associated protein 23
       K08512  VAMP8; vesicle-associated membrane protein 8
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
       K06751  MHC1; major histocompatibility complex, class I
       K07980  KIR3DL; killer cell immunoglobulin-like receptor 3DL
       K07981  KIR2DL; killer cell immunoglobulin-like receptor 2DL
       K06541  KLRC; killer cell lectin-like receptor subfamily C
       K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
       K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K06490  ICAM1; intercellular adhesion molecule 1
       K06523  ICAM2; intercellular adhesion molecule 2
       K05718  ITGAL; integrin alpha L
       K06464  ITGB2; integrin beta 2
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04687  IFNG; interferon gamma
       K07982  KIR2DS; killer cell immunoglobulin-like receptor 2DS
       K06742  NCR2; natural cytotoxicity triggering receptor 2
       K07992  TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K06856  IGH; immunoglobulin heavy chain
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
       K06741  NCR1; natural cytotoxicity triggering receptor 1
       K06743  NCR3; natural cytotoxicity triggering receptor 3
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K06453  CD3Z; CD3Z antigen, zeta polypeptide
       K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K07361  LCP2; lymphocyte cytosolic protein 2
       K07362  LAT; linker for activation of T cells
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07984  SH3BP2; SH3-domain binding protein 2
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K07985  MIC; MHC class I-related protein
       K07986  ULBP; UL16 binding protein
       K07987  RAET1; retinoic acid early transcript 1
       K06728  KLRK1; killer cell lectin-like receptor subfamily K member 1
       K07988  HCST, DAP10; hematopoietic cell signal transducer
       K06479  CD48, BCM1; CD48 antigen
       K06582  CD244; natural killer cell receptor 2B4
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K07989  EAT2; EWS/FLI1 activated transcript 2
       K07990  SH2D1A, SAP; SH2 domain protein 1A
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K04721  TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K01353  GZMB; granzyme B [EC:3.4.21.79]
       K07818  PRF1; perforin 1
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04662 B cell receptor signaling pathway [PATH:ko04662]
       K06856  IGH; immunoglobulin heavy chain
       K06506  CD79A, IGA; CD79A antigen
       K06507  CD79B, IGB; CD79B antigen
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K12229  DAPP1, BAM32; dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
       K07371  BLNK; B-cell linker protein
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K07367  CARD11; caspase recruitment domain-containing protein 11
       K07368  BCL10; B-cell CLL/lymphoma 10
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K06508  CD81, TAPA1, TSPAN28; CD81 antigen
       K06465  CD19; CD19 antigen
       K04012  CR2, CD21; complement receptor type 2
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K03084  SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
       K06467  CD22, SIGLEC2; CD22 antigen
       K06504  CD72; CD72 antigen
       K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
       K06856  IGH; immunoglobulin heavy chain
       K08089  FCER1A; Fc receptor, IgE, high affinity I, alpha polypeptide
       K08090  MS4A2, FCER1B; membrane-spanning 4-domains, subfamily A, member 2
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K03084  SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K05430  IL4; interleukin 4
       K05435  IL13; interleukin 13
       K04736  IL3; interleukin 3
       K05428  IL5; interleukin 5
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05730  VAV; guanine nucleotide exchange factor VAV
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K07362  LAT; linker for activation of T cells
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
       K06856  IGH; immunoglobulin heavy chain
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K06478  PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
       K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12561  MARCKS; myristoylated alanine-rich C-kinase substrate
       K13536  MARCKSL1, MRP; MARCKS-related protein
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K01080  PPAP2; phosphatidate phosphatase [EC:3.1.3.4]
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K05768  GSN; gelsolin
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04393  CDC42; cell division control protein 42
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K05753  WASF1; WAS protein family, member 1
       K05748  WASF2; WAS protein family, member 2
       K06083  WASF3; WAS protein family, member 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
       K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
       K05765  CFL; cofilin
       K00889  E2.7.1.68, PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
       K07941  ARF6; ADP-ribosylation factor 6
       K04438  CRK, CRKII; proto-oncogene C-crk
       K12367  DOCK2; dedicator of cytokinesis protein 2
       K12488  ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
       K03084  SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K07362  LAT; linker for activation of T cells
       K12562  AMPH; amphiphysin
       K12559  MYO10; myosin X
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
 
   Endocrine system
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
     04320 Dorso-ventral axis formation [PATH:ko04320]
     04360 Axon guidance [PATH:ko04360]
     04380 Osteoclast differentiation [PATH:ko04380]
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11220  STAT1; signal transducer and activator of transcription 1
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K05473  TNFSF11, RANKL; tumor necrosis factor ligand superfamily member 11
       K05147  TNFRSF11A, RANK; tumor necrosis factor receptor superfamily member 11A
       K05148  TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
       K03173  TRAF2; TNF receptor-associated factor 2
       K03175  TRAF6; TNF receptor-associated factor 6
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K05415  IFNB; interferon beta
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K09029  FOSB; protein FosB
       K09030  FOSL2; fos-like antigen 2
       K04502  FOSL1; fos-like antigen 1
       K04448  JUN; transcription factor AP-1
       K04449  JUND; transcription factor jun-D
       K09028  JUNB; transcription factor jun-B
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K08008  NOX, GP91; NADPH oxidase
       K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
       K08010  NCF2, P67PHOX; neutrophil cytosolic factor 2
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K08012  NCF4, P40PHOX; neutrophil cytosolic factor 4
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K07364  TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
       K14377  OSCAR; osteoclast-associated immunoglobulin-like receptor
       K06512  LILR; leukocyte immunoglobulin-like receptor
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
       K16824  FCGR2C, CD32; low affinity immunoglobulin gamma Fc region receptor II-c
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
       K14378  TREM2; triggering receptor expressed on myeloid cells 2
       K06551  SIRPA_B1_G; signal-regulatory protein alpha/beta1/gamma
       K07992  TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K07371  BLNK; B-cell linker protein
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09438  SPI1; transcription factor PU.1
       K09455  MITF; microphthalmia-associated transcription factor
       K01371  CTSK; cathepsin K [EC:3.4.22.38]
       K14379  ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
       K04576  CALCR; calcitonin receptor
       K06493  ITGB3; integrin beta 3
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K08091  GAB2; growth factor receptor bound protein 2-associated protein 2
       K14380  FHL2; four and a half LIM domains protein 2
       K08601  CYLD, USLP2; ubiquitin thioesterase CYLD [EC:3.1.2.15]
       K14381  SQSTM1; sequestosome 1
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K10610  DDB1; DNA damage-binding protein 1
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08665  HPN; hepsin (transmembrane protease, serine 1) [EC:3.4.21.-]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04735  RELA; transcription factor p65
       K09254  REL; c-Rel proto-oncogene protein
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04451  TP53, P53; tumor protein p53
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K12496  EGR2; early growth response protein 2
       K12497  EGR3; early growth response protein 3
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K15413  SP100; nuclear autoantigen Sp-100
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K11252  H2B; histone H2B
       K11254  H4; histone H4
       K02159  BAX; apoptosis regulator BAX
       K04364  GRB2; growth factor receptor-binding protein 2
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K06053  RBPSUH, RBPJK; recombining binding protein suppressor of hairless
       K06063  SNW1, SKIIP, SKIP; SNW domain-containing protein 1
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K03136  TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
       K03137  TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
       K15979  SND1; staphylococcal nuclease domain-containing protein 1
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K03124  TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06627  CCNA; cyclin A
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K16174  MRPS18B, MRPS18-2; small subunit ribosomal protein S18b, mitochondrial
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K10587  UBE3A, E6AP; ubiquitin-protein ligase E3 A [EC:6.3.2.19]
       K12076  DLG1; disks large protein 1
       K16175  SCRIB; protein scribble
       K05760  PXN; paxillin
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K05411  IRF3; interferon regulatory factor 3
       K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2
       K06618  RB1; retinoblastoma-associated protein
       K04681  RBL1; retinoblastoma-like protein 1
       K16332  RBL2; retinoblastoma-like protein 2
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K10691  UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19]
       K04448  JUN; transcription factor AP-1
       K11643  CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K11404  HDAC3; histone deacetylase 3 [EC:3.5.1.98]
       K11406  HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
       K11407  HDAC6_10; histone deacetylase 6/10 [EC:3.5.1.98]
       K11408  HDAC7; histone deacetylase 7 [EC:3.5.1.98]
       K11405  HDAC8; histone deacetylase 8 [EC:3.5.1.98]
       K11409  HDAC9; histone deacetylase 9 [EC:3.5.1.98]
       K11418  HDAC11; histone deacetylase 11 [EC:3.5.1.98]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K09504  DNAJA3; DnaJ homolog subfamily A member 3
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K03122  TFIIA1, GTF2A1, TOA1; transcription initiation factor TFIIA large subunit
       K03123  TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit
       K04378  SRF; serum response factor
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04513  RHOA; Ras homolog gene family, member A
       K05768  GSN; gelsolin
       K05699  ACTN; actinin alpha
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K09447  IRF7; interferon regulatory factor 7
       K05060  IL6ST, GP130; interleukin 6 signal transducer
       K04180  CCR5; C-C chemokine receptor type 5
       K04183  CCR8; C-C chemokine receptor type 8
       K04178  CCR3; C-C chemokine receptor type 3
       K04179  CCR4; C-C chemokine receptor type 4
       K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02158  BAD; BCL2-antagonist of cell death
       K10131  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       K03990  C3; complement component 3
       K06751  MHC1; major histocompatibility complex, class I
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
       K02159  BAX; apoptosis regulator BAX
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02084  APAF1; apoptotic protease-activating factor
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02158  BAD; BCL2-antagonist of cell death
       K02161  BCL2; apoptosis regulator BCL-2
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K08060  CIITA; class II, major histocompatibility complex, transactivator
       K08061  RFX5; regulatory factor X 5
       K08062  RFXANK; regulatory factor X-associated ankyrin-containing protein
       K08063  RFXAP; regulatory factor X-associated protein
       K08064  NFYA; nuclear transcription factor Y, alpha
       K08065  NFYB; nuclear transcription Y subunit beta
       K08066  NFYC; nuclear transcription factor Y, gamma
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K06752  MHC2; major histocompatibility complex, class II
       K06505  CD74, DHLAG; CD74 antigen
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K05443  IL10, CSIF; interleukin 10
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K01368  CTSS; cathepsin S [EC:3.4.22.27]
       K10059  CLEC4E; C-type lectin domain family 4 member E
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K10074  CLEC7A; C-type lectin domain family 7 member A
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K12794  CARD9; caspase recruitment domain-containing protein 9
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K07368  BCL10; B-cell CLL/lymphoma 10
       K14952  namH; UDP-MurNAc hydroxylase
       K10165  NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K14953  lpqH; ipoprotein LpqH
       K14954  lprG; lipoprotein LprG
       K14955  lprA; lipoprotein LprA
       K02040  pstS; phosphate transport system substrate-binding protein
       K04043  dnaK; molecular chaperone DnaK
       K04077  groEL, HSPD1; chaperonin GroEL
       K14956  esxA, esat6; 6 kDa early secretory antigenic target
       K05399  LBP; lipopolysaccharide-binding protein
       K10159  TLR2; toll-like receptor 2
       K05398  TLR1; toll-like receptor 1
       K10169  TLR6; toll-like receptor 6
       K10160  TLR4; toll-like receptor 4
       K04391  CD14; CD14 antigen
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05482  IL18, IL1F4; interleukin 18
       K05426  IL23A; interleukin 23, alpha subunit p19
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K10048  CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
       K10049  CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
       K10161  TLR9; toll-like receptor 9
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K06563  CD209; CD209 antigen
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K14957  LSP1; lymphocyte-specific protein 1
       K08862  PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
       K14958  KSR1; kinase suppressor of Ras 1
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K07438  CYP27B; 25-hydroxyvitamin D3 1alpha-hydroxylase [EC:1.14.13.13]
       K08539  NR1I1, VDR; vitamin D3 receptor
       K13916  CAMP, LL37; cathelicidin antimicrobial peptide
       K03990  C3; complement component 3
       K04011  CR1, CD35; complement component (3b/4b) receptor 1
       K06462  ITGAX; integrin alpha X
       K06464  ITGB2; integrin beta 2
       K06461  ITGAM; integrin alpha M
       K06560  MRC; mannose receptor, C type
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K02183  CALM; calmodulin
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K12478  EEA1; early endosome antigen 1
       K07897  RAB7A; Ras-related protein Rab-7A
       K01379  CTSD; cathepsin D [EC:3.4.23.5]
       K02154  ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02155  ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
       K03661  ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
       K06528  LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
       K01078  E3.1.3.2; acid phosphatase [EC:3.1.3.2]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K13882  CORO1A; coronin-1A
       K14949  pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
       K06856  IGH; immunoglobulin heavy chain
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
       K16824  FCGR2C, CD32; low affinity immunoglobulin gamma Fc region receptor II-c
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05168 Herpes simplex infection [PATH:ko05168]
     05169 Epstein-Barr virus infection [PATH:ko05169]
       K04012  CR2, CD21; complement receptor type 2
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
       K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
       K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
       K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
       K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
       K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
       K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
       K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
       K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
       K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
       K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
       K14290  XPO1, CRM1; exportin-1
       K07936  RAN; GTP-binding nuclear protein Ran
       K14317  NUP214, CAN; nuclear pore complex protein Nup214
       K06751  MHC1; major histocompatibility complex, class I
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K06477  SPN, CD43; sialophorin
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K15978  AKAP8L, HA95; A-kinase anchor protein 8-like protein
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04455  HSPB1; heat shock protein beta-1
       K09543  HSPB2; heat shock protein beta-2
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K03124  TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
       K15979  SND1; staphylococcal nuclease domain-containing protein 1
       K03136  TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
       K03137  TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
       K11406  HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
       K06063  SNW1, SKIIP, SKIP; SNW domain-containing protein 1
       K06065  NCOR2, SMRT; nuclear receptor co-repressor 2
       K06053  RBPSUH, RBPJK; recombining binding protein suppressor of hairless
       K09438  SPI1; transcription factor PU.1
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K13784  PTMA; prothymosin alpha
       K06468  FCER2, CD23; Fc receptor, IgE, low affinity II
       K08891  FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
       K04377  MYC; Myc proto-oncogene protein
       K04451  TP53, P53; tumor protein p53
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K03061  PSMC2, RPT1; 26S proteasome regulatory subunit T1
       K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2
       K03063  PSMC4, RPT3; 26S proteasome regulatory subunit T3
       K03064  PSMC6, RPT4; 26S proteasome regulatory subunit T4
       K03065  PSMC3, RPT5; 26S proteasome regulatory subunit T5
       K03066  PSMC5, RPT6; 26S proteasome regulatory subunit T6
       K03028  PSMD2, RPN1; 26S proteasome regulatory subunit N1
       K03032  PSMD1, RPN2; 26S proteasome regulatory subunit N2
       K03033  PSMD3, RPN3; 26S proteasome regulatory subunit N3
       K03035  PSMD12, RPN5; 26S proteasome regulatory subunit N5
       K03036  PSMD11, RPN6; 26S proteasome regulatory subunit N6
       K03037  PSMD6, RPN7; 26S proteasome regulatory subunit N7
       K03038  PSMD7, RPN8; 26S proteasome regulatory subunit N8
       K03039  PSMD13, RPN9; 26S proteasome regulatory subunit N9
       K03029  PSMD4, RPN10; 26S proteasome regulatory subunit N10
       K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
       K03031  PSMD8, RPN12; 26S proteasome regulatory subunit N12
       K06691  RPN13; 26S proteasome regulatory subunit N13
       K10881  SHFM1, DSS1; 26 proteasome complex subunit DSS1
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06627  CCNA; cyclin A
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K01510  ENTPD1_3_8; apyrase [EC:3.6.1.5]
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K06256  CD44; CD44 antigen
       K05718  ITGAL; integrin alpha L
       K06492  CD58, LFA3; CD58 antigen
       K06490  ICAM1; intercellular adhesion molecule 1
       K07606  VIM; vimentin
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19]
       K02161  BCL2; apoptosis regulator BCL-2
       K06856  IGH; immunoglobulin heavy chain
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K06465  CD19; CD19 antigen
       K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K04687  IFNG; interferon gamma
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K05443  IL10, CSIF; interleukin 10
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 12, 2014