KEGG Orthology (KO)

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 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
     00250 Alanine, aspartate and glutamate metabolism [PATH:ko00250]
     00260 Glycine, serine and threonine metabolism [PATH:ko00260]
     00270 Cysteine and methionine metabolism [PATH:ko00270]
     00280 Valine, leucine and isoleucine degradation [PATH:ko00280]
     00290 Valine, leucine and isoleucine biosynthesis [PATH:ko00290]
     00300 Lysine biosynthesis [PATH:ko00300]
     00310 Lysine degradation [PATH:ko00310]
       K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]
       K00291  E1.5.1.8; saccharopine dehydrogenase (NADP+, L-lysine forming) [EC:1.5.1.8]
       K00292  E1.5.1.9; saccharopine dehydrogenase (NAD+, L-glutamate forming) [EC:1.5.1.9]
       K14157  AASS; alpha-aminoadipic semialdehyde synthase [EC:1.5.1.8 1.5.1.9]
       K00293  LYS9; saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]
       K00143  LYS2; L-aminoadipate-semialdehyde dehydrogenase [EC:1.2.1.31]
       K14085  ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
       K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
       K00164  OGDH, sucA; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
       K00658  DLST, sucB; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
       K00252  GCDH, gcdH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
       K01692  paaF, echA; enoyl-CoA hydratase [EC:4.2.1.17]
       K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
       K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
       K07515  HADHA; enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
       K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
       K07511  ECHS1; enoyl-CoA hydratase [EC:4.2.1.17]
       K00022  HADH; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
       K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
       K18201  AGPHD1; hydroxylysine kinase [EC:2.7.1.81]
       K18202  AGXT2L2; 5-phosphonooxy-L-lysine phospho-lyase [EC:4.2.3.134]
       K01582  E4.1.1.18, ldcC, cadA; lysine decarboxylase [EC:4.1.1.18]
       K14268  davT, gabT; 5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19]
       K00135  gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
       K03897  iucD; lysine N6-hydroxylase [EC:1.14.13.59]
       K03896  iucB; acetyl CoA:N6-hydroxylysine acetyl transferase [EC:2.3.1.102]
       K03894  iucA; N2-citryl-N6-acetyl-N6-hydroxylysine synthase [EC:6.3.2.38]
       K03895  iucC; aerobactin synthase [EC:6.3.2.39]
       K01843  kamA; lysine 2,3-aminomutase [EC:5.4.3.2]
       K01844  kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3]
       K18011  kamE; beta-lysine 5,6-aminomutase beta subunit [EC:5.4.3.3]
       K18012  kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11]
       K18013  kce; 3-keto-5-aminohexanoate cleavage enzyme
       K18014  kal; 3-aminobutyryl-CoA ammonia-lyase [EC:4.3.1.14]
       K01034  atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
       K01035  atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
       K00824  dat; D-alanine transaminase [EC:2.6.1.21]
       K13609  dpkA; delta1-piperideine-2-carboxylate reductase [EC:1.5.1.21]
       K00306  PIPOX; sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7]
       K06101  ASH1L; histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43]
       K11427  DOT1L, DOT1; histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
       K11420  EHMT; euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43]
       K15588  NSD1; histone-lysine N-methyltransferase NSD1 [EC:2.1.1.43]
       K11424  WHSC1, MMSET, NSD2; histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]
       K11425  WHSC1L1, NSD3; histone-lysine N-methyltransferase NSD3 [EC:2.1.1.43]
       K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43]
       K11423  SETD2, SET2; histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43]
       K11431  SETD7; histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43]
       K11428  SETD8; histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43]
       K11421  SETDB1; histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]
       K18494  SETDB2; histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43]
       K11433  SETMAR; histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43]
       K11419  SUV39H, CLR4; histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43]
       K11429  SUV420H; histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43]
       K09186  MLL1; histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]
       K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]
       K09188  MLL3; histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]
       K14959  MLL4; histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43]
       K09189  MLL5; histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43]
       K01423  E3.4.-.-;  [EC:3.4.-.-]
       K00474  E1.14.11.8; trimethyllysine dioxygenase [EC:1.14.11.8]
       K00128  E1.2.1.3; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
       K00149  ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
       K00471  E1.14.11.1; gamma-butyrobetaine dioxygenase [EC:1.14.11.1]
       K00473  PLOD1; procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4]
       K13645  PLOD2; procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4]
       K13646  PLOD3; lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]
       K13647  PLODN; procollagen-lysine,2-oxoglutarate 5-dioxygenase, invertebrate [EC:1.14.11.4]
       K11703  GLT25D; collagen beta-1,O-galactosyltransferase [EC:2.4.1.50]
     00330 Arginine and proline metabolism [PATH:ko00330]
     00340 Histidine metabolism [PATH:ko00340]
     00350 Tyrosine metabolism [PATH:ko00350]
     00360 Phenylalanine metabolism [PATH:ko00360]
     00380 Tryptophan metabolism [PATH:ko00380]
     00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:ko00400]
     01007 Amino acid related enzymes [BR:ko01007]
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
 
   Cellular commiunity
     04510 Focal adhesion [PATH:ko04510]
     04520 Adherens junction [PATH:ko04520]
     04530 Tight junction [PATH:ko04530]
       K06087  CLDN; claudin
       K06088  OCLN; occludin
       K06089  F11R, JAM1; junctional adhesion molecule 1
       K06735  JAM2; junctional adhesion molecule 2
       K06785  JAM3; junctional adhesion molecule 3
       K06786  JAM4, JCAM; junctional adhesion molecule 4
       K06090  CRB3; crumbs 3
       K06091  MPP5, PALS1; MAGUK p55 subfamily member 5
       K06092  INADL, PATJ; InaD-like protein
       K06093  PARD6; partitioning defective protein 6
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K04237  PARD3; partitioning defective protein 3
       K06094  LLGL; lethal(2) giant larvae protein
       K04393  CDC42; cell division control protein 42
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K06095  MPDZ, MUPP1, Patj; multiple PDZ domain protein
       K06096  VAPA; vesicle-associated membrane protein-associated protein A
       K06097  TJP3, ZO3; tight junction protein 3
       K05701  TJP1, ZO1; tight junction protein 1
       K06098  TJP2, ZO2; tight junction protein 2
       K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]
       K02105  CTNNB1; catenin beta 1
       K06099  CSDA, ZONAB; cold shock domain protein A
       K06100  SYMPK; symplekin
       K06101  ASH1L; histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06102  CGN; cingulin
       K05692  ACTB_G1; actin beta/gamma 1
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K10352  MYH; myosin heavy chain
       K17751  MYH6_7; myosin heavy chain 6/7
       K04513  RHOA; Ras homolog gene family, member A
       K05702  AF6, MLLT4; afadin
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K06103  CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
       K06104  AMOTL1, JEAP; angiomotin like 1
       K06105  TJP4, PILT; tight junction protein 4 (peripheral)
       K06106  CTTN, EMS1; cortactin
       K05691  CTNNA; catenin alpha
       K06107  EPB41, 4.1R; erythrocyte membrane protein band 4.1
       K05699  ACTN; actinin alpha
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05705  YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
       K06108  RAB3B; Ras-related protein Rab-3B
       K06109  RAB13; Ras-related protein Rab-13
       K06110  EXOC3, SEC6L1; exocyst complex component 3
       K06111  EXOC4, SEC8L1; exocyst complex component 4
       K05631  AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
       K05629  AIP1; atrophin-1 interacting protein 1
       K06112  MAGI3; membrane-associated guanylate kinase-related
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
     04540 Gap junction [PATH:ko04540]
     04550 Signaling pathways regulating pluripotency of stem cells [PATH:ko04550]
 
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Last updated: September 30, 2014