 Metabolism
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Genetic Information Processing
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 Environmental Information Processing
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Membrane transport
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Signal transduction
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02020 Two-component system [PATH:ko02020]
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 02022 Two-component system [BR:ko02022]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway -fly [PATH:ko04391]
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04370 VEGF signaling pathway [PATH:ko04370]
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04630 Jak-STAT signaling pathway [PATH:ko04630]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; nerve growth factor receptor (TNFR superfamily member 16)
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2; toll-like receptor 2
K10160 TLR4; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; CD19 antigen
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05071 IL4R; interleukin 4 receptor
K05072 IL7R; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 GBL; G protein beta subunit-like
K07203 FRAP; FKBP12-rapamycin complex-associated protein
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K06071 PKN; protein kinase N [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; thioesterase superfamily member 4
K04382 PPP2C; protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; protein phosphatase 2 (formerly 2A), regulatory subunit A
K04354 PPP2R2; protein phosphatase 2 (formerly 2A), regulatory subunit B
K11583 PPP2R3; protein phosphatase 2 (formerly 2A), regulatory subunit B''
K11584 PPP2R5; protein phosphatase 2 (formerly 2A), regulatory subunit B'
K04079 htpG, HSP90A; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen(starch) synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; cyclin D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; cyclin D2
K10152 CCND3; cyclin D3
K06626 CCNE; cyclin E
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; BCL2-antagonist of cell death
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator BCL-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 NR2B1, RXRA; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB; myb proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
K04451 TP53, P53; tumor protein p53
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
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04150 mTOR signaling pathway [PATH:ko04150]
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04075 Plant hormone signal transduction [PATH:ko04075]
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Signaling molecules and interaction
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04030 G protein-coupled receptors [BR:ko04030]
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01020 Enzyme-linked receptors [BR:ko01020]
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04050 Cytokine receptors [BR:ko04050]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
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04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
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04052 Cytokines [BR:ko04052]
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04512 ECM-receptor interaction [PATH:ko04512]
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K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06254 AGRN; agrin
K06255 HSPG2; heparan sulfate proteoglycan 2 (perlecan)
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K06256 CD44; CD44 antigen
K06257 SDC1; syndecan 1
K16338 SDC4; syndecan 4
K06258 SV2; MFS transporter, VNT family, synaptic vesicle glycoprotein 2
K06259 CD36; CD36 antigen
K06260 GP5; platelet glycoprotein V
K06261 GP1BA; platelet glycoprotein Ib alpha chain
K06262 GP1BB; platelet glycoprotein Ib beta chain
K06263 GP9; platelet glycoprotein IX
K06264 GP6; platelet glycoprotein VI
K06265 DAG1; dystroglycan 1
K06266 CD47; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
K06267 HMMR, RHAMM; hyaluronan-mediated motility receptor
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04514 Cell adhesion molecules (CAMs) [PATH:ko04514]
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K06492 CD58, LFA3; CD58 antigen
K06449 CD2; CD2 antigen
K05412 CD80; CD80 antigen
K06745 PDCD1LG1, CD274; programmed cell death 1 ligand 1
K06470 CD28; CD28 antigen
K05413 CD86; CD86 antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K06710 ICOSLG, ICOSL; inducible T-cell co-stimulator ligand
K06713 ICOS, AILIM; inducible T-cell co-stimulator
K06752 MHC2; major histocompatibility complex, class II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06454 CD4; CD4 antigen
K06751 MHC1; major histocompatibility complex, class I
K06458 CD8A; CD8A antigen, alpha polypeptide
K06459 CD8B; CD8B antigen, beta polypeptide
K06708 PDCD1LG2, CD273; programmed cell death 1 ligand 2
K06746 B7H3, CD276; immune costimulatory protein B7-H3
K06747 B7H4, VTCN1; immune costimulatory protein B7-H4
K06744 PDCD1, PD1; programmed cell death protein 1
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K06547 ALCAM; activated leukocyte cell adhesion molecule
K06456 CD6; CD6 antigen
K06539 PVR, NECL5; poliovirus receptor
K06567 CD226, DNAM1; CD226 antigen
K06531 PVRL2; poliovirus receptor-related protein 2
K16350 TIGIT; T-cell immunoreceptor with Ig and ITIM domains
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06490 ICAM1; intercellular adhesion molecule 1
K06523 ICAM2; intercellular adhesion molecule 2
K06486 ICAM3; intercellular adhesion molecule 3
K06467 CD22, SIGLEC2; CD22 antigen
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K06548 SN, SIGLEC1; sialoadhesin
K06477 SPN, CD43; sialophorin
K06592 PVRL3; poliovirus receptor-related protein 3
K06087 CLDN; claudin
K06088 OCLN; occludin
K06089 F11R, JAM1; junctional adhesion molecule 1
K06735 JAM2; junctional adhesion molecule 2
K06785 JAM3; junctional adhesion molecule 3
K06787 ESAM; endothelial cell adhesion molecule
K06533 CDH5; cadherin 5, type 2, VE-cadherin
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K06520 CD99, MIC2; CD99 antigen
K06461 ITGAM; integrin alpha M
K06544 SELPLG; selectin P ligand
K06496 SELP; selectin, platele
K06483 ITGA4; integrin alpha 4
K05719 ITGB1; integrin beta 1
K06585 ITGA9; integrin alpha 9
K06527 VCAM1; vascular cell adhesion molecule 1
K06590 ITGB7; integrin beta 7
K06779 MADCAM1; mucosal vascular addressin cell adhesion molecule 1
K06495 SELL; selectin, lymphocyte
K06815 GLYCAM1; glycosylation dependent cell adhesion molecule 1
K06474 CD34; CD34 antigen
K06816 GLG1, ESL1; golgi apparatus protein 1
K06494 SELE; selectin, endothelial cell
K06081 PVRL1; poliovirus receptor-related protein 1
K06736 CDH2, NCAD; cadherin 2, type 1, N-cadherin
K06491 NCAM; neural cell adhesion molecule
K06550 L1CAM; L1 cell adhesion molecule
K06781 CADM1, IGSF4, NECL2, TSLC1; cell adhesion molecule 1
K06775 NEGR1; neuronal growth regulator 1
K07522 NTNG1; netrin-G1
K07523 LRRC4C, NGL1; netrin-G1 ligand
K16359 NTNG2; netrin-G2
K16351 LRRC4, NGL2; netrin-G2 ligand
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K16360 LRRC4B, NGL3; netrin-G3 ligand
K06257 SDC1; syndecan 1
K16336 SDC2; syndecan 2
K16337 SDC3; syndecan 3
K16338 SDC4; syndecan 4
K06487 ITGAV; integrin alpha V
K06591 ITGB8; integrin beta 8
K06584 ITGA8; integrin alpha 8
K07377 NRXN; neurexin
K07378 NLGN; neuroligin
K06780 CADM3, IGSF4B, NECL1, TSLL1; cell adhesion molecule 3
K06756 NRCAM; neuronal cell adhesion molecule
K06759 CNTN1; contactin 1
K05693 PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
K06760 CNTN2; contactin 2
K06757 NFASC; neurofascin
K07379 CNTNAP1; contactin associated protein 1
K07380 CNTNAP2; contactin associated protein-like 2
K06770 MPZ; myelin protein zero
K06771 MAG, GMA, SIGLEC4; myelin associated glycoprotein
K05689 CDHE, CDH1; cadherin 1, type 1, E-cadherin
K06793 VCAN, CSPG2; versican core protein
K06485 ITGA6; integrin alpha 6
K06796 CDH3; cadherin 3, type 1, P-cadherin
K06797 CDH4; cadherin 4, type 1, R-cadherin
K06809 CDH15, CDH3, CDH14; cadherin 15, M-cadherin
K06766 NEO1; neogenin
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04516 Cell adhesion molecules and their ligands [BR:ko04516]
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04090 CD Molecules [BR:ko04090]
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04091 Glycan bindng proteins [BR:ko04091]
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02042 Bacterial toxins [BR:ko02042]
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Cellular Processes
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Transport and catabolism
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Cell motility
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02030 Bacterial chemotaxis [PATH:ko02030]
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02035 Bacterial motility proteins [BR:ko02035]
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02040 Flagellar assembly [PATH:ko02040]
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04810 Regulation of actin cytoskeleton [PATH:ko04810]
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K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04391 CD14; CD14 antigen
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05717 FN1; fibronectin 1
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05718 ITGAL; integrin alpha L
K06461 ITGAM; integrin alpha M
K06462 ITGAX; integrin alpha X
K06594 ITGAD; integrin alpha D
K06524 ITGAE; integrin alpha E
K05719 ITGB1; integrin beta 1
K06464 ITGB2; integrin beta 2
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K05720 FGD1; FYVE, RhoGEF and PH domain containing 1
K05722 FGD3; FYVE, RhoGEF and PH domain containing 3
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; proto-oncogene C-crk
K13708 DOCK1; dedicator of cytokinesis 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05729 ARHGEF6, PIXA; Rho guanine nucleotide exchange factor 6
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K05730 VAV; guanine nucleotide exchange factor VAV
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K05732 GRLF1; glucocorticoid receptor DNA-binding factor 1
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05736 PAK7; p21-activated kinase 7 [EC:2.7.11.1]
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K05737 GIT1; G protein-coupled receptor kinase interactor 1
K04514 ROCK; Rho-associated protein kinase [EC:2.7.11.1]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K06269 PPP1C; protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05740 DIAPH1; diaphanous 1
K05741 DIAPH2; diaphanous 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K00889 E2.7.1.68, PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00920 E2.7.1.149, PIP4K; 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149]
K00921 PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K05744 LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
K05745 DIAPH3, DRF3; diaphanous 3
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05746 ENAH, MENA; enabled
K05747 WAS; Wiskott-Aldrich syndrome protein
K05748 WASF2; WAS protein family, member 2
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05750 NCKAP1, NAP125; NCK-associated protein 1
K05751 ABI2; abl interactor 2
K05752 C3ORF10, HSPC300; chromosome 3 open reading frame 10
K05753 WASF1; WAS protein family, member 1
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05692 ACTB_G1; actin beta/gamma 1
K05759 PFN; profilin
K05760 PXN; paxillin
K08007 VIL2; villin 2 (ezrin)
K05762 RDX; radixin
K05763 MSN; moesin
K05764 TMSB4; thymosin, beta 4
K05765 CFL; cofilin
K05766 SSH; slingshot
K05700 VCL; vinculin
K16848 IQGAP1; Ras GTPase-activating-like protein IQGAP1
K05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2/3
K05768 GSN; gelsolin
K05699 ACTN; actinin alpha
K02085 APC; adenomatosis polyposis coli protein
K05769 ARHGEF4, ASEF; Rho guanine nucleotide exchange factor 4
|
04812 Cytoskeleton proteins [BR:ko04812]
|
|
Cell growth and death
|
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Cell communication
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04510 Focal adhesion [PATH:ko04510]
|
K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
K06237 COL4A; collagen, type IV, alpha
K06238 COL6A; collagen, type VI, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05098 KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05083 ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05732 GRLF1; glucocorticoid receptor DNA-binding factor 1
K13709 ARHGAP5; Rho GTPase-activating protein 5
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK; Rho-associated protein kinase [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K06269 PPP1C; protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K05692 ACTB_G1; actin beta/gamma 1
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K05699 ACTN; actinin alpha
K06271 TLN; talin
K04437 FLNA; filamin
K05760 PXN; paxillin
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06273 ZYX; zyxin
K06274 VASP; vasodilator-stimulated phosphoprotein
K05700 VCL; vinculin
K06275 PARV; parvin
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05736 PAK7; p21-activated kinase 7 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; proto-oncogene C-crk
K13708 DOCK1; dedicator of cytokinesis 1
K06277 RAPGEF1, GRF2; Rap guanine nucleotide exchange factor (GEF) 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC; src homology 2 domain-containing transforming protein C
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K04503 CCND1; cyclin D1
K10151 CCND2; cyclin D2
K10152 CCND3; cyclin D3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K02158 BAD; BCL2-antagonist of cell death
K02161 BCL2; apoptosis regulator BCL-2
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04520 Adherens junction [PATH:ko04520]
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04530 Tight junction [PATH:ko04530]
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04540 Gap junction [PATH:ko04540]
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Organismal Systems
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Human Diseases
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Cancers
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Immune diseases
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Neurodegenerative diseases
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Substance dependence
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Cardiovascular diseases
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05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
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K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K12563 SGCD; delta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K06265 DAG1; dystroglycan 1
K07610 DES; desmin
K10366 DMD; dystrophin
K05692 ACTB_G1; actin beta/gamma 1
K12567 TTN; titin [EC:2.7.11.1]
K12045 TNNT2; troponin T, cardiac muscle
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12044 TNNI3; troponin I, cardiac muscle
K12314 ACTC1; actin, alpha cardiac muscle
K10373 TPM1; tropomyosin 1
K10374 TPM2; tropomyosin 2
K09290 TPM3; tropomyosin 3
K10375 TPM4; tropomyosin 4
K12568 MYBPC3; myosin-binding protein C, cardiac-type
K12749 MYL3; myosin light chain 3
K10351 MYL2; myosin regulatory light chain 2
K12569 EMD; emerin
K12641 LMNA; lamin A/C
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04962 RYR2; ryanodine receptor 2
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K01283 E3.4.15.1, ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
K05459 IGF1; insulin-like growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03156 TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K16366 EDN1; endothelin-1
K09821 AGT; angiotensinogen
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05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
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K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K12563 SGCD; delta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K06265 DAG1; dystroglycan 1
K10366 DMD; dystrophin
K07610 DES; desmin
K05692 ACTB_G1; actin beta/gamma 1
K12569 EMD; emerin
K12641 LMNA; lamin A/C
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04962 RYR2; ryanodine receptor 2
K06736 CDH2, NCAD; cadherin 2, type 1, N-cadherin
K10056 JUP; junction plakoglobin
K05691 CTNNA; catenin alpha
K05699 ACTN; actinin alpha
K07601 DSC2; desmocollin 2
K12642 PKP2; plakophilin 2
K10381 DSP; desmoplakin
K07597 DSG2; desmoglein 2
K07372 GJA1, CX43; gap junction protein, alpha 1
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05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
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K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K12563 SGCD; delta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K06265 DAG1; dystroglycan 1
K07610 DES; desmin
K10366 DMD; dystrophin
K05692 ACTB_G1; actin beta/gamma 1
K12567 TTN; titin [EC:2.7.11.1]
K12045 TNNT2; troponin T, cardiac muscle
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12044 TNNI3; troponin I, cardiac muscle
K12314 ACTC1; actin, alpha cardiac muscle
K10373 TPM1; tropomyosin 1
K10374 TPM2; tropomyosin 2
K09290 TPM3; tropomyosin 3
K10375 TPM4; tropomyosin 4
K12568 MYBPC3; myosin-binding protein C, cardiac-type
K12749 MYL3; myosin light chain 3
K10351 MYL2; myosin regulatory light chain 2
K12569 EMD; emerin
K12641 LMNA; lamin A/C
K06856 IGH; immunoglobulin heavy chain
K04141 ADRB1; adrenergic receptor beta-1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05459 IGF1; insulin-like growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03156 TNFA; tumor necrosis factor superfamily, member 2
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05416 Viral myocarditis [PATH:ko05416]
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Endocrine and metabolic diseases
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Infectious diseases
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KEGG Orthology (KO)