KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
   Transcription
     03020 RNA polymerase [PATH:ko03020]
     03022 Basal transcription factors [PATH:ko03022]
       K03122  TFIIA1, GTF2A1, TOA1; transcription initiation factor TFIIA large subunit
       K03123  TFIIA2, GTF2A2, TOA2; transcription initiation factor TFIIA small subunit
       K03124  TFIIB, GTF2B, SUA7, tfb; transcription initiation factor TFIIB
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K03125  TAF1; transcription initiation factor TFIID subunit 1
       K03128  TAF2; transcription initiation factor TFIID subunit 2
       K03132  TAF7; transcription initiation factor TFIID subunit 7
       K14649  TAF8; transcription initiation factor TFIID subunit 8
       K14650  TAF3; transcription initiation factor TFIID subunit 3
       K03134  TAF10; transcription initiation factor TFIID subunit 10
       K03130  TAF5; transcription initiation factor TFIID subunit 5
       K03129  TAF4; transcription initiation factor TFIID subunit 4
       K03126  TAF12; transcription initiation factor TFIID subunit 12
       K03131  TAF6; transcription initiation factor TFIID subunit 6
       K14535  TAF9; transcription initiation factor TFIID subunit 9
       K03133  TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
       K03140  TAF14; transcription initiation factor TFIID/TFIIF subunit
       K03135  TAF11; transcription initiation factor TFIID subunit 11
       K03127  TAF13; transcription initiation factor TFIID subunit 13
       K14651  TAF15; transcription initiation factor TFIID subunit 15
       K03136  TFIIE1, GTF2E1, TFA1, tfe; transcription initiation factor TFIIE subunit alpha
       K03137  TFIIE2, GTF2E2, TFA2; transcription initiation factor TFIIE subunit beta
       K03138  TFIIF1, GTF2F1, TFG1; transcription initiation factor TFIIF subunit alpha
       K03139  TFIIF2, GTF2F2, TFG2; transcription initiation factor TFIIF subunit beta [EC:3.6.4.12]
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K10843  ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
       K10844  ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
       K10845  TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K10842  MNAT1; CDK-activating kinase assembly factor MAT1
       K06634  CCNH; cyclin H
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
     03000 Transcription factors [BR:ko03000]
     03021 Transcription machinery [BR:ko03021]
     03040 Spliceosome [PATH:ko03040]
     03041 Spliceosome [BR:ko03041]
 
   Translation
 
   Folding, sorting and degradation
 
   Replication and repair
     03030 DNA replication [PATH:ko03030]
     03032 DNA replication proteins [BR:ko03032]
     03036 Chromosome and associated proteins [BR:ko03036]
     03410 Base excision repair [PATH:ko03410]
     03420 Nucleotide excision repair [PATH:ko03420]
       K03723  mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]
       K03701  uvrA; excinuclease ABC subunit A
       K03702  uvrB; excinuclease ABC subunit B
       K03703  uvrC; excinuclease ABC subunit C
       K03657  uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
       K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       K03868  RBX1, ROC1; RING-box protein 1
       K10609  CUL4; cullin 4
       K10610  DDB1; DNA damage-binding protein 1
       K10140  DDB2; DNA damage-binding protein 2
       K10838  XPC; xeroderma pigmentosum group C-complementing protein
       K10839  RAD23, HR23; UV excision repair protein RAD23
       K10840  CETN2; centrin-2
       K10570  ERCC8, CKN1, CSA; DNA excision repair protein ERCC-8
       K10841  ERCC6, CSB, RAD26; DNA excision repair protein ERCC-6
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K10842  MNAT1; CDK-activating kinase assembly factor MAT1
       K06634  CCNH; cyclin H
       K10843  ERCC3, XPB; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
       K10844  ERCC2, XPD; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
       K10845  TTDA, GTF2H5, TFB5; TFIIH basal transcription factor complex TTD-A subunit
       K03141  TFIIH1, GTF2H1, TFB1; transcription initiation factor TFIIH subunit 1
       K03142  TFIIH2, GTF2H2, SSL1; transcription initiation factor TFIIH subunit 2
       K03143  TFIIH3, GTF2H3, TFB4; transcription initiation factor TFIIH subunit 3
       K03144  TFIIH4, GTF2H4, TFB2; transcription initiation factor TFIIH subunit 4
       K10846  ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
       K10847  XPA; DNA-repair protein complementing XP-A cells
       K07466  RFA1, RPA1, rpa; replication factor A1
       K10739  RFA2, RPA2; replication factor A2
       K10740  RPA3; replication factor A3
       K10741  RPA4; replication factor A4
       K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
       K10849  ERCC1; DNA excision repair protein ERCC-1
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04802  PCNA; proliferating cell nuclear antigen
       K10754  RFC1; replication factor C subunit 1
       K10755  RFC2_4; replication factor C subunit 2/4
       K10756  RFC3_5; replication factor C subunit 3/5
       K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
     03430 Mismatch repair [PATH:ko03430]
     03440 Homologous recombination [PATH:ko03440]
     03450 Non-homologous end-joining [PATH:ko03450]
     03460 Fanconi anemia pathway [PATH:ko03460]
     03400 DNA repair and recombination proteins [BR:ko03400]
 
   RNA family
 
 Environmental Information Processing
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K04681  RBL1; retinoblastoma-like protein 1
       K16332  RBL2; retinoblastoma-like protein 2
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04682  E2F4_5; transcription factor E2F4/5
       K04683  TFDP1; transcription factor Dp-1
       K09392  TFDP2; transcription factor Dp-2
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04377  MYC; Myc proto-oncogene protein
       K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K06623  CDKN2D, P19, INK4D; cyclin-dependent kinase inhibitor 2D
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K09993  CDKN1C, P57, KIP2; cyclin-dependent kinase inhibitor 1C
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03347  CUL1, CDC53; cullin 1
       K03868  RBX1, ROC1; RING-box protein 1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K06627  CCNA; cyclin A
       K02213  CDC6; cell division control protein 6
       K06628  CDC45; cell division control protein 45
       K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
       K06629  ASK, DBF4; activator of S phase kinase
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K05868  CCNB; cyclin B
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K06632  WEE1; wee1-like protein kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K06634  CCNH; cyclin H
       K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K06671  STAG1_2, SCC3, IRR1; cohesin complex subunit SA-1/2
       K06670  SCC1, MCD1, RAD21; cohesin complex subunit SCC1
       K08866  TTK, MPS1; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K04802  PCNA; proliferating cell nuclear antigen
       K06644  SFN; stratifin
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K02603  ORC1; origin recognition complex subunit 1
       K02604  ORC2; origin recognition complex subunit 2
       K02605  ORC3; origin recognition complex subunit 3
       K02606  ORC4; origin recognition complex subunit 4
       K02607  ORC5; origin recognition complex subunit 5
       K02608  ORC6; origin recognition complex subunit 6
       K02540  MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
       K02541  MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
       K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:3.6.4.12]
       K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:3.6.4.12]
       K02542  MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
       K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
     04115 p53 signaling pathway [PATH:ko04115]
 
   Cellular commiunity
 
 Organismal Systems
 
 Human Diseases

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Last updated: September 18, 2014