KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K09782  AREG; amphiregulin
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
       K07365  NCK; NCK adaptor protein
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K05736  PAK7; p21-activated kinase 7 [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09783  BTC; betacellulin
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K09784  EREG; epiregulin
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05455  NRG1; neuregulin 1
       K05456  NRG2; neuregulin 2
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04377  MYC; Myc proto-oncogene protein
       K09593  GAB1; GRB2-associated-binding protein 1
       K05457  NRG3; neuregulin 3
       K05458  NRG4; neuregulin 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K02158  BAD; BCL2-antagonist of cell death
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
       K05405  IL6; interleukin 6
       K05055  IL6R; interleukin 6 receptor
       K04692  STAT3; signal transducer and activator of transcription 3
       K10160  TLR4; toll-like receptor 4
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04526  INS; insulin
       K04357  EGF; epidermal growth factor
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03868  RBX1, ROC1; RING-box protein 1
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K08008  NOX, GP91; NADPH oxidase
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K16451  TIMP1; metallopeptidase inhibitor 1
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K05437  EPO; erythropoietin
       K14736  TF; transferrin
       K06503  TFRC, CD71; transferrin receptor
       K05448  VEGFA; vascular endothelial growth factor A
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K16366  EDN1; endothelin-1
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12334  NPPA; natriuretic peptide A
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K12077  PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
       K01689  ENO, eno; enolase [EC:4.2.1.11]
       K01103  PFKFB; 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
       K02161  BCL2; apoptosis regulator BCL-2
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K00161  PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
       K00162  PDHB, pdhB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2; toll-like receptor 2
       K10160  TLR4; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; CD19 antigen
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K04737  IL3RA; interleukin 3 receptor alpha
       K05055  IL6R; interleukin 6 receptor
       K05071  IL4R; interleukin 4 receptor
       K05072  IL7R; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K06626  CCNE; cyclin E
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; BCL2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator BCL-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB; myb proto-oncogene protein
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
     04152 AMPK signaling pathway [PATH:ko04152]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K08272  CAB39, MO25; calcium binding protein 39
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K01103  PFKFB; 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatase [EC:2.7.1.105 3.1.3.46]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K07292  NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K04503  CCND1; cyclin D1
       K06627  CCNA; cyclin A
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K00021  HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
       K00507  SCD, desC; stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1]
       K01578  MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K18341  TBC1D1; TBC1 domain family member 1
       K07877  RAB2A; Ras-related protein Rab-2A
       K07901  RAB8A, MEL; Ras-related protein Rab-8A
       K07903  RAB10; Ras-related protein Rab-10
       K07905  RAB11B; Ras-related protein Rab-11B
       K07881  RAB14; Ras-related protein Rab-14
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K06259  CD36; CD36 antigen
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07207  TSC2; tuberous sclerosis 2
       K07206  TSC1; tuberous sclerosis 1
       K07208  RHEB; Ras homolog enriched in brain
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
     04150 mTOR signaling pathway [PATH:ko04150]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K16172  IRS1; insulin receptor substrate 1
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  GBL; G protein beta subunit-like
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K08267  RICTOR; rapamycin-insensitive companion of mTOR
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K05448  VEGFA; vascular endothelial growth factor A
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K08269  ULK1_2_3, ATG1; serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K08272  CAB39, MO25; calcium binding protein 39
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen(starch) synthase [EC:2.4.1.11]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K17453  PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
       K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
       K07190  PHKA_B; phosphorylase kinase alpha/beta subunit
       K02183  CALM; calmodulin
       K00688  E2.4.1.1, glgP, PYG; starch phosphorylase [EC:2.4.1.1]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07192  FLOT; flotillin
       K07193  APS, SH2B2; SH2B adapter protein 2
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K07194  RHOQ, TC10; Ras homolog gene family, member Q
       K07195  EXOC7, EXO70; exocyst complex component 7
       K07196  TRIP10, CIP4; thyroid hormone receptor interactor 10
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07201  FOXO1; forkhead box protein O1
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K02158  BAD; BCL2-antagonist of cell death
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K03173  TRAF2; TNF receptor-associated factor 2
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K06259  CD36; CD36 antigen
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K05228  POMC; proopiomelanocortin
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K05231  AGRP; agouti related protein
       K05232  NPY; neuropeptide Y
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06487  ITGAV; integrin alpha V
       K06493  ITGB3; integrin beta 3
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K11220  STAT1; signal transducer and activator of transcription 1
       K04451  TP53, P53; tumor protein p53
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K08362  NR1A2, THRB; thyroid hormone receptor beta
       K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
       K11644  SIN3A; paired amphipathic helix protein Sin3a
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K11404  HDAC3; histone deacetylase 3 [EC:3.5.1.98]
       K05547  NR1A1, THRA; thyroid hormone receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09101  NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
       K11255  NCOA2, TIF2, KAT13C; nuclear receptor coactivator 2
       K11256  NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K15146  MED4; mediator of RNA polymerase II transcription subunit 4
       K15162  MED12; mediator of RNA polymerase II transcription subunit 12
       K15164  MED13; mediator of RNA polymerase II transcription subunit 13
       K15156  MED14, RGR1; mediator of RNA polymerase II transcription subunit 14
       K15159  MED16; mediator of RNA polymerase II transcription subunit 16
       K15133  MED17; mediator of RNA polymerase II transcription subunit 17
       K15167  MED24; mediator of RNA polymerase II transcription subunit 24
       K15170  MED27; mediator of RNA polymerase II transcription subunit 27
       K15143  MED30; mediator of RNA polymerase II transcription subunit 30
       K15144  MED1; mediator of RNA polymerase II transcription subunit 1
       K04503  CCND1; cyclin D1
       K09183  GATA4; GATA-binding protein 4
       K17901  RCAN1, MCIP1; calcipressin-1
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K04377  MYC; Myc proto-oncogene protein
       K05852  PLN; phospholamban
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K02105  CTNNB1; catenin beta 1
       K02599  NOTCH; Notch
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05857  PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K01114  plcC; phospholipase C [EC:3.1.4.3]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K08231  SLC16A2; MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 2
       K08187  SLC16A10; MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K17902  TBC1D4, AS160; TBC1 domain family member 4
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K17903  RCAN2, ZAKI4; calcipressin-2
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K08747  SLCO1C; solute carrier organic anion transporter family, member 1C
       K01562  DIO1; type I thyroxine 5'-deiodinase [EC:1.97.1.10]
       K17904  DIO2; type II thyroxine 5'-deiodinase [EC:1.97.1.10]
       K07754  DIO3; thyroxine 5-deiodinase [EC:1.97.1.11]
       K05692  ACTB_G1; actin beta/gamma 1
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K02353  DVL; segment polarity protein dishevelled
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator BCL-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04358  FGF; fibroblast growth factor
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04513  RHOA; Ras homolog gene family, member A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05405  IL6; interleukin 6
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04496  CTBP; C-terminal binding protein
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K02159  BAX; apoptosis regulator BAX
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03868  RBX1, ROC1; RING-box protein 1
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06227  COS2; costal 2
       K06228  FU; fused [EC:2.7.11.1]
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K04662  BMP2_4; bone morphogenetic protein 2/4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  NR3C4, AR; androgen receptor
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
       K17002  MIR17; microRNA 17
       K17003  MIR18A; microRNA 18a
       K17005  MIR19; microRNA 19
       K17006  MIR20A; microRNA 20a
       K17008  MIR92A; microRNA 92a
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K17010  MIR221; microRNA 221
       K17011  MIR222; microRNA 222
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K16863  MIR21; microRNA 21
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16980  MIRLET7; microRNA let-7
       K17397  MIRLET7C; microRNA let-7c
       K07827  KRAS, KRAS2; GTPase KRas
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K09283  HMGA2; high mobility group AT-hook protein 2
       K17396  MIR107; microRNA 107
       K16986  MIR15A; microRNA 15a
       K16987  MIR15B; microRNA 15b
       K16988  MIR16; microRNA 16
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K06626  CCNE; cyclin E
       K16978  MIR126; microRNA 126
       K04438  CRK, CRKII; proto-oncogene C-crk
       K16972  MIR1; microRNA 1
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K16995  MIR29A; microRNA 29a
       K16996  MIR29B; microRNA 29b
       K16997  MIR29C; microRNA 29c
       K17398  DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
       K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
       K16970  MIR133A; microRNA 133a
       K16971  MIR133B; microRNA 133b
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K02163  BCLW; apoptosis regulator BCL-W
       K16974  MIR145; microRNA 145
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05448  VEGFA; vascular endothelial growth factor A
       K17017  MIR200C; microRNA 200c
       K17018  MIR141; microRNA 141
       K13376  TGFB2; transforming growth factor beta-2
       K17116  MIR183; microRNA 183
       K08007  VIL2; villin 2 (ezrin)
       K16993  MIR125A; microRNA 125a
       K16994  MIR125B; microRNA 125b
       K16865  PDCD4; programmed cell death protein 4
       K17023  MIR143; microRNA 143
       K17131  MIR192; microRNA 192
       K17371  MIR194; microRNA 194
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K17167  MIR215; microRNA 215
       K17366  MIR28; microRNA 28
       K17110  MIR30A_D_E; microRNA 30a/d/e
       K17111  MIR30B; microRNA 30b
       K17040  MIR30C; microRNA 30c
       K10373  TPM1; tropomyosin 1
       K17383  SPRY2; protein sprouty homolog 2
       K02161  BCL2; apoptosis regulator BCL-2
       K10139  SERPINB5; serpin B5
       K17009  MIR155; microRNA 155
       K16975  MIR203; microRNA 203
       K17150  MIR205; microRNA 205
       K09299  ZEB1_2; zinc finger homeobox protein 1/2
       K17112  MIR27A; microRNA 27a
       K17113  MIR27B; microRNA 27b
       K08670  ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
       K07410  CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
       K17183  MIR31; microRNA 31
       K17367  MIR99A; microRNA 99a
       K17041  MIR100; microRNA 100
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07436  CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.13.126]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K10149  TP63; tumor protein p63
       K16976  MIR375; microRNA 375
       K17379  MIR602; microRNA 602
       K09850  RASSF1; Ras association domain-containing protein 1
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K17460  BMF; Bcl-2-modifying factor
       K17042  MIR224; microRNA 224
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K17036  MIR363; microRNA 363
       K17378  MIR494; microRNA 494
       K17380  MIR615; microRNA 615
       K17381  MIR625; microRNA 625
       K17038  MIR25; microRNA 25
       K16982  MIR34A; microRNA 34a
       K17114  MIR96; microRNA 96
       K16864  MIR10A; microRNA 10a
       K17165  MIR23A; microRNA 23a
       K17394  MIR23B; microRNA 23b
       K17395  MIR23C; microRNA 23c
       K17020  MIR122; microRNA 122
       K13863  SLC7A1, ATRC1; solute carrier family 7 (cationic amino acid transporter), member 1
       K10145  CCNG1; cyclin G1
       K17024  MIR150; microRNA 150
       K17001  MIR223; microRNA 223
       K04381  STMN1; stathmin
       K17132  MIR342; microRNA 342
       K17376  MIR423; microRNA 423
       K04692  STAT3; signal transducer and activator of transcription 3
       K04377  MYC; Myc proto-oncogene protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K17119  MIR199B; microRNA 199b
       K17152  MIR324; microRNA 324
       K17137  MIR483; microRNA 483
       K16984  MIR26A; microRNA 26a
       K16985  MIR26B; microRNA 26b
       K17370  MIR152; microRNA 152
       K00558  DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
       K17144  MIR135; microRNA 135
       K02085  APC; adenomatosis polyposis coli protein
       K16172  IRS1; insulin receptor substrate 1
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K17015  MIR200A; microRNA 200a
       K17016  MIR200B; microRNA 200b
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K17461  RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs
       K17126  MIR124; microRNA 124
       K17369  MIR137; microRNA 137
       K17130  MIR128; microRNA 128
       K06620  E2F3; transcription factor E2F3
       K17365  MIR7; microRNA 7
       K07187  IRS2; insulin receptor substrate 2
       K17372  MIR326; microRNA 326
       K02599  NOTCH; Notch
       K11459  PCGF4, BMI1; polycomb group RING finger protein 4
       K17012  MIR146A; microRNA 146a
       K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
       K17025  MIR181A; microRNA 181a
       K17026  MIR181B; microRNA 181b
       K17027  MIR181C; microRNA 181c
       K17028  MIR181D; microRNA 181d
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K17000  MIR373; microRNA 373
       K17175  MIR520; microRNA 520
       K06256  CD44; CD44 antigen
       K16989  MIR103; microRNA 103
       K11592  DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
       K02329  FZD3; frizzled 3
       K06484  ITGA5; integrin alpha 5
       K05762  RDX; radixin
       K04513  RHOA; Ras homolog gene family, member A
       K17148  MIR193B; microRNA 193b
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K17442  ZFPM2, FOG2; zinc finger protein ZFPM2
       K06493  ITGB3; integrin beta 3
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19]
       K17033  MIR335; microRNA 335
       K06252  TN; tenascin
       K16973  MIR206; microRNA 206
       K17172  MIR451; microRNA 451
       K05658  ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]
       K17375  MIR345; microRNA 345
       K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
       K17151  MIR214; microRNA 214
       K10605  BRCA1; breast cancer type 1 susceptibility protein
       K17035  MIR106B; microRNA 106b
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K17178  MIR210; microRNA 210
       K16857  THBS1; thrombospondin 1
       K17391  IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:6.3.2.19]
       K16977  MIR9; microRNA 9
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K17118  MIR199A; microRNA 199a
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04364  GRB2; growth factor receptor-binding protein 2
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K10127  MDM4, MDMX; protein Mdm4
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K17129  MIR101; microRNA 101
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K17029  MIR195; microRNA 195
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K03099  SOS; son of sevenless
       K06279  SHC1; SHC- transforming protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17368  MIR129; microRNA 129
       K17449  SHC4; SHC- transforming protein 4
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K17039  MIR32; microRNA 32
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K12561  MARCKS; myristoylated alanine-rich C-kinase substrate
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K17377  MIR449A; microRNA 449a
       K11430  EZH2; histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K17373  MIR330; microRNA 330
       K17374  MIR331; microRNA 331
       K17390  CDCA5; sororin
       K17387  KIF23; kinesin family member 23
       K17389  MIR520C; microRNA 520c
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K15379  SLC45A3; solute carrier family 45, member 3
       K07606  VIM; vimentin
     05205 Proteoglycans in cancer [PATH:ko05205]
       K06256  CD44; CD44 antigen
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06106  CTTN, EMS1; cortactin
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K04393  CDC42; cell division control protein 42
       K04375  ELK1; ETS domain-containing protein Elk-1
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K04503  CCND1; cyclin D1
       K05692  ACTB_G1; actin beta/gamma 1
       K04437  FLNA; filamin
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10380  ANK; ankyrin
       K09593  GAB1; GRB2-associated-binding protein 1
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K10164  NANOG; homeobox protein Nanog
       K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
       K03685  rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
       K04692  STAT3; signal transducer and activator of transcription 3
       K16863  MIR21; microRNA 21
       K09069  TWIST; twist
       K16864  MIR10A; microRNA 10a
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K04660  DCN; decorin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06278  CAV1; caveolin 1
       K12958  CAV2; caveolin 2
       K12959  CAV3; caveolin 3
       K06497  CD63, MLA1, TSPAN30; CD63 antigen
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K13375  TGFB1; transforming growth factor beta-1
       K10159  TLR2; toll-like receptor 2
       K10160  TLR4; toll-like receptor 4
       K16865  PDCD4; programmed cell death protein 4
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05425  IL12B; interleukin 12B
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04377  MYC; Myc proto-oncogene protein
       K02105  CTNNB1; catenin beta 1
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09108  TFAP4; transcription factor AP-4
       K05448  VEGFA; vascular endothelial growth factor A
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16857  THBS1; thrombospondin 1
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K08122  LUM; lumican
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K13376  TGFB2; transforming growth factor beta-2
       K07964  HPSE; heparanase 1 [EC:3.2.1.166]
       K07965  HPSE2; heparanase 2 [EC:3.2.1.-]
       K06257  SDC1; syndecan 1
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K03985  PLAUR; plasminogen activator, urokinase receptor
       K06481  ITGA2; integrin alpha 2
       K05719  ITGB1; integrin beta 1
       K06251  VTN; vitronectin
       K06487  ITGAV; integrin alpha V
       K06493  ITGB3; integrin beta 3
       K05717  FN1; fibronectin 1
       K06588  ITGB5; integrin beta 5
       K05460  HGF; hepatocyte growth factor
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K06484  ITGA5; integrin alpha 5
       K16336  SDC2; syndecan 2
       K08007  VIL2; villin 2 (ezrin)
       K05762  RDX; radixin
       K05763  MSN; moesin
       K16338  SDC4; syndecan 4
       K04358  FGF; fibroblast growth factor
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K12461  FRS2; fibroblast growth factor receptor substrate 2
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K16867  NUDT16L1, SDOS; NUDT16-like protein 1
       K05760  PXN; paxillin
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K08107  GPC1; glypican 1
       K13769  IGF2; insulin-like growth factor 2
       K08109  GPC3; glypican 3 (OCI-5)
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K06224  HH; hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06255  HSPG2; heparan sulfate proteoglycan 2 (perlecan)
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K09543  HSPB2; heat shock protein beta-2
       K05697  PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04503  CCND1; cyclin D1
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02158  BAD; BCL2-antagonist of cell death
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K04688  RPS6KB; p70 ribosomal S6 kinase [EC:2.7.11.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K07827  KRAS, KRAS2; GTPase KRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K09438  SPI1; transcription factor PU.1
       K10056  JUP; junction plakoglobin
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K04503  CCND1; cyclin D1
       K04377  MYC; Myc proto-oncogene protein
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04526  INS; insulin
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K05459  IGF1; insulin-like growth factor 1
       K05086  INSRR; insulin receptor-related receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K02105  CTNNB1; catenin beta 1
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K04503  CCND1; cyclin D1
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02161  BCL2; apoptosis regulator BCL-2
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
       K08557  NR3C4, AR; androgen receptor
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3; semenogelase [EC:3.4.21.77]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
     04940 Type I diabetes mellitus [PATH:ko04940]
     04930 Type II diabetes mellitus [PATH:ko04930]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07296  ACDC; adiponectin
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K07594  IPF1, PDX1; insulin promoter factor 1
       K07595  MAFA; transcription factor MAFA
       K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K05004  KCNJ11; potassium inwardly-rectifying channel subfamily J member 11
       K05032  ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04852  CACNA1E; voltage-dependent calcium channel R type alpha-1E
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
     04950 Maturity onset diabetes of the young [PATH:ko04950]
     04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:ko04932]
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 10, 2014